disease_position_superficial
superficial
Candida parapsilosis is an opportunistic human pathogen which may cause both superficial and systemic candidosis in the compromised host. Although less common than C. albicans, it has been associated with vaginitis, peritonitis, oral candidosis, urinary tract infection, septicaemia and endocarditis and represents approximately 5 to 10% of clinical yeast isolates. Meunier-Carpenter isolated C. parapsilosis from 13 out of 82 cancer patients with candidaemia (Am. J. Med. 71: 368-370, 1981). Candida parapsilosis appears to play an important role in the incidence of candida endocarditis. Odds (1979) in a review of 112 cases found 25.8% due to C. parapsilosis, 54.8% to C. albicans and the remainder to a variety of other yeasts. There appears to be a link between C. parapsilosis endocarditis and intra-venous drug abuse. Reisberg found this organism to be the most common blood culture isolate from drug abusers (Prog. Cardiovasc. Dis. 22: 193-204, 1976) and it has also been isolated from heroin syringes used by drug abusers (Brandstett et al., JAMA 243: 1073, 1980. Isolates from animals appear to be rare, although the organism has been implicated in cases of bovine mastitis. Candida parapsilosis has been shown to cause gastrointestinal overgrowth in antibiotic-treated mice, resulting in spread to visceral organs (Kennedy, Sabouraudia 21: 27-33, 1983) and to be lethal to alloxan-treated mice (Andriole et al., Yale. J. Biol. Med. 35: 96-112, 1962), however, attempts to infect untreated mice have failed. Equivocal results have been obtained in attempts to produce skin lesions in laboratory animals.
Mycotorula parapsilosis
Candida parapsilosis