Probenecid, a prototypical uricosuric agent and chemical inhibitor of organic anion transporters known to target OAT3, was shown to be effective in limiting influenza A virus infection in vitro (50% inhibitory concentration [IC(50)] of 5.0 &#215; 10(-5) to 5.0 &#215; 10(-4) &#956;M; P &lt; 0.005) and in vivo (P &lt; 0.05).
C0021400
Influenza