Meta-analysis identified 19 genome-wide significant single nucleotide polymorphisms (SNPs) in C9orf72 on chromosome 9p21.2 (lowest p = 2.6 &#215; 10(-12) ) and 1 SNP in UNC13A on chromosome 19p13.11 (p = 1.0 &#215; 10(-11) ) as shared susceptibility loci for ALS and FTD-TDP.
C0002736
Amyotrophic Lateral Sclerosis