To determine a plane, we need three non-collinear points.
So, if we have 12 points in space, we can choose any three of them to determine a plane.
The number of ways to choose 3 points out of 12 is given by the combination formula, $\binom{12}{3}=\frac{12!}{3!(12-3)!}=220$.
Therefore, the maximum possible number of planes that can be determined by 12 points in space is $\boxed{220}$.
The answer is: 220
Below is a math problem. Provide a detailed, step-by-step solution.

### Problem:
A plane is uniquely determined by three non-collinear points. What is the maximum possible number of planes that can be determined by 12 points in space?

### Answer:
