<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>francisofascii</author><text>I think there is a large percentage of people who got the original mRNA vaccine but don&amp;#x27;t plan on getting it again, due to being sick for several days or from other &amp;quot;long covid&amp;quot; or vaccine injury fears. So I wonder if that group would be more receptive.</text><parent_chain><item><author>sethammons</author><text>&amp;gt; “Unlike the mRNA vaccine which targets only the spike protein, CDO-7N-1 induces immunity to all major SARS-CoV-2 proteins and is highly effective against all major variants to date.&lt;p&gt;&amp;gt; “Importantly, the vaccine remains stable at 4°C for seven months, making it ideal for low- and middle-income countries.”&lt;p&gt;This being a more traditional vaccine, I wonder if any vaccine hold outs will be more receptive</text></item></parent_chain></comment><story><title>Covid-19 Intranasal Vaccine</title><url>https://news.griffith.edu.au/2024/08/27/game-changing-needle-free-covid-19-intranasal-vaccine/</url></story>
<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>ifyoubuildit</author><text>Is nasal delivery a traditional thing?&lt;p&gt;Assuming they actually mean that it would stop you from getting and transmitting covid with high probability, and that they&amp;#x27;re correct, thats a pretty attractive selling point.&lt;p&gt;But like with any other pharma innovation, I&amp;#x27;m not gonna be a part of the first commercial wave, or even the second or third unless I&amp;#x27;m incredibly worried about the alternative, which I&amp;#x27;m not at the moment (although let&amp;#x27;s see how hard this thing is &amp;quot;marketed&amp;quot; - am I going to be able to live life without it?).</text><parent_chain><item><author>sethammons</author><text>&amp;gt; “Unlike the mRNA vaccine which targets only the spike protein, CDO-7N-1 induces immunity to all major SARS-CoV-2 proteins and is highly effective against all major variants to date.&lt;p&gt;&amp;gt; “Importantly, the vaccine remains stable at 4°C for seven months, making it ideal for low- and middle-income countries.”&lt;p&gt;This being a more traditional vaccine, I wonder if any vaccine hold outs will be more receptive</text></item></parent_chain></comment><story><title>Covid-19 Intranasal Vaccine</title><url>https://news.griffith.edu.au/2024/08/27/game-changing-needle-free-covid-19-intranasal-vaccine/</url></story>