<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>doodlebugging</author><text>About 40 years ago I boarded my horse with an old cowboy who used DMSO as a horse liniment. He had been using it for years any time one of his mounts was worked pretty hard or when someone brought a lame horse to him. He would rub the joints, calves, and thighs of the horse down good with DMSO for a few days and then they were good to go again.&lt;p&gt;He also used it on his wife. He told me that she had type I diabetes and neuropathy as a result. Her feet were always cold from poor circulation. That was true until he happened to rub her feet one day after treating a horse. Her feet warmed up in minutes and became normal pink again. After that, he used it on her feet and legs since it improved circulation.&lt;p&gt;You can say what you will about it being reactive and possibly not good for you but she was able to dance again and get back on her horse so it definitely does have some benefit. They did this for at least 30 years and both of them were past 75 years old when they passed away.&lt;p&gt;Like another poster said, it is used as a carrier for some medications since it pulls them straight into the bloodstream. I don&amp;#x27;t think it&amp;#x27;s magic but I also don&amp;#x27;t think you&amp;#x27;ll suffer much using it even with bare hands.&lt;p&gt;As far as lye is concerned, the sodium hydroxide in this paper, you can easily make that yourself with wood ash and water. It is pretty handy if you are tanning hides since the treatment of a raw hide with lye causes the hair to slip right off leaving a smooth skin ready for the next step.</text><parent_chain><item><author>sbierwagen</author><text>The paper: &lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.science.org&amp;#x2F;doi&amp;#x2F;10.1126&amp;#x2F;science.abm8868&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.science.org&amp;#x2F;doi&amp;#x2F;10.1126&amp;#x2F;science.abm8868&lt;/a&gt;&lt;p&gt;The &amp;quot;soap and solvent&amp;quot; is sodium hydroxide (lye) and DMSO at 120 degC. Those are... fairly... well behaved chemicals, but lye is stout stuff and DMSO attacks nitrile gloves.&lt;p&gt;You could imagine a remediation process that uses this process but the combo ain&amp;#x27;t exactly Dawn dish soap. I&amp;#x27;d almost prefer pyroprocessing over it.</text></item></parent_chain></comment><story><title>Simple mix of soap and solvent could help destroy ‘forever chemicals’</title><url>https://www.science.org/content/article/simple-mix-soap-and-solvent-could-help-destroy-forever-chemicals</url></story>
<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>chasil</author><text>DMSO is &lt;i&gt;not&lt;/i&gt; well-behaved. It easily penetrates human skin, and carries solutes with it. Don&amp;#x27;t touch!&lt;p&gt;&amp;quot;DMSO can cause contaminants, toxins, and medicines to be absorbed through the skin, which may cause unexpected effects.&lt;p&gt;&amp;quot;Because DMSO easily penetrates the skin, substances dissolved in DMSO may be quickly absorbed. Glove selection is important when working with DMSO. Butyl rubber, fluoroelastomer, neoprene, or thick (15 mil &amp;#x2F; 0.4  mm) latex gloves are recommended. Nitrile gloves, which are very commonly used in chemical laboratories, may protect from brief contact but have been found to degrade rapidly with exposure to DMSO.&amp;quot;&lt;p&gt;&lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;en.m.wikipedia.org&amp;#x2F;wiki&amp;#x2F;Dimethyl_sulfoxide&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;en.m.wikipedia.org&amp;#x2F;wiki&amp;#x2F;Dimethyl_sulfoxide&lt;/a&gt;</text><parent_chain><item><author>sbierwagen</author><text>The paper: &lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.science.org&amp;#x2F;doi&amp;#x2F;10.1126&amp;#x2F;science.abm8868&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.science.org&amp;#x2F;doi&amp;#x2F;10.1126&amp;#x2F;science.abm8868&lt;/a&gt;&lt;p&gt;The &amp;quot;soap and solvent&amp;quot; is sodium hydroxide (lye) and DMSO at 120 degC. Those are... fairly... well behaved chemicals, but lye is stout stuff and DMSO attacks nitrile gloves.&lt;p&gt;You could imagine a remediation process that uses this process but the combo ain&amp;#x27;t exactly Dawn dish soap. I&amp;#x27;d almost prefer pyroprocessing over it.</text></item></parent_chain></comment><story><title>Simple mix of soap and solvent could help destroy ‘forever chemicals’</title><url>https://www.science.org/content/article/simple-mix-soap-and-solvent-could-help-destroy-forever-chemicals</url></story>