<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>DevX101</author><text>Here is an image comparing the lethal dose of heroin vs fentanyl.&lt;p&gt;&lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.statnews.com&amp;#x2F;wp-content&amp;#x2F;uploads&amp;#x2F;2016&amp;#x2F;09&amp;#x2F;Heroin-Fentanyl-vials-NHSPFL-1024x576.jpg&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.statnews.com&amp;#x2F;wp-content&amp;#x2F;uploads&amp;#x2F;2016&amp;#x2F;09&amp;#x2F;Heroin-F...&lt;/a&gt;</text><parent_chain><item><author>esotericn</author><text>This article seems pretty low on detail. Almost all of it seems to be talking about, well, not the drug in question.&lt;p&gt;What, exactly, does &amp;quot;10x more powerful&amp;quot; mean?&lt;p&gt;Potency? Presumably it&amp;#x27;d then be prescribed in lower doses?</text></item></parent_chain></comment><story><title>Despite concerns, FDA approves new opioid 10x more powerful than Fentanyl</title><url>https://www.statnews.com/pharmalot/2018/11/02/fda-dsuvia-fentanyl-approval/</url></story>
<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>dogma1138</author><text>It’s the the binding strength which has direct impact on addiction and withdrawal which is a bit scary since Fentanyl is 100 times stronger than morphine already, heroine is only 5 times as strong for comparison.</text><parent_chain><item><author>esotericn</author><text>This article seems pretty low on detail. Almost all of it seems to be talking about, well, not the drug in question.&lt;p&gt;What, exactly, does &amp;quot;10x more powerful&amp;quot; mean?&lt;p&gt;Potency? Presumably it&amp;#x27;d then be prescribed in lower doses?</text></item></parent_chain></comment><story><title>Despite concerns, FDA approves new opioid 10x more powerful than Fentanyl</title><url>https://www.statnews.com/pharmalot/2018/11/02/fda-dsuvia-fentanyl-approval/</url></story>