<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>vikramkr</author><text>I&amp;#x27;ll just note that the link between amyloid and alzheimers isn&amp;#x27;t concrete and is actually an incredibly controversial area of research[0]. The most recent attempt at treating alzheimers via amyloid is not going so well[1]. So, the causality implied by this article (poor sleep -&amp;gt; amyloid buildup -&amp;gt; alzheimers) isn&amp;#x27;t necessarily on the strongest theoretical footing.&lt;p&gt;[0]&lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.nature.com&amp;#x2F;articles&amp;#x2F;d41586-018-05719-4&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.nature.com&amp;#x2F;articles&amp;#x2F;d41586-018-05719-4&lt;/a&gt;&lt;p&gt;[1]&lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.sciencemag.org&amp;#x2F;news&amp;#x2F;2020&amp;#x2F;11&amp;#x2F;biogen-s-alzheimer-s-drug-candidate-takes-beating-fda-advisers&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.sciencemag.org&amp;#x2F;news&amp;#x2F;2020&amp;#x2F;11&amp;#x2F;biogen-s-alzheimer-s...&lt;/a&gt;</text><parent_chain></parent_chain></comment><story><title>Poor Sleep Linked with Future Amyloid-β Build Up</title><url>https://www.the-scientist.com/news-opinion/poor-sleep-linked-with-future-amyloid-build-up-67923</url></story>
<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>asdfasgasdgasdg</author><text>People will be tempted to infer causation here, but it&amp;#x27;s important to note that no evidence of causation is presented. It is most likely that some third condition causes both poor sleep and amyloid-b accumulation (since correlation usually doesn&amp;#x27;t indicate causation).</text><parent_chain></parent_chain></comment><story><title>Poor Sleep Linked with Future Amyloid-β Build Up</title><url>https://www.the-scientist.com/news-opinion/poor-sleep-linked-with-future-amyloid-build-up-67923</url></story>