<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>tempestn</author><text>I don&amp;#x27;t really understand the comments here, and especially on the article itself, deriding this research because &amp;quot;people should just get off their butts and exercise&amp;quot; or similar.  I&amp;#x27;m sure the researchers wouldn&amp;#x27;t dispute the benefits of exercise.  But if there really is a safe, effective way to improve the metabolism and make it easier to keep off fat, why exactly is that a bad thing?  (Naturally the research is far too early on to know that, but hypothetically speaking.)  Of course you should continue to exercise and stay healthy in other ways, but that doesn&amp;#x27;t mean we shouldn&amp;#x27;t also look for other ways to make it easier for people to get to, or remain at, a healthy weight.</text><parent_chain></parent_chain></comment><story><title>McMaster researchers may have found a way to restore metabolism to youth levels</title><url>http://www.cbc.ca/news/canada/hamilton/news/want-to-eat-like-a-teen-again-science-may-have-found-a-way-1.2862231</url></story>
<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>eldude</author><text>Based on the findings of this article, the OTC EGCG should &amp;quot;restore metabolism to youth levels.&amp;quot;&lt;p&gt;Using a decarboxylase or AADC[0] inhibitor like EGCG[1] found in green tea extract limits peripheral serotonin metabolism, especially if you&amp;#x27;re supplementing with serotonin precursors like tryptophan or 5-HTP to avoid heart-valve issues.[2]&lt;p&gt;See Examine.com&amp;#x27;s note in the 5-HTP article[3] and the associated citation.[4] 800mg of EGCG 2 hours prior to supplementation demonstrated decarboxylase inhibition.&lt;p&gt;[0] &lt;a href=&quot;http://en.wikipedia.org/wiki/Aromatic_L-amino_acid_decarboxylase&quot; rel=&quot;nofollow&quot;&gt;http:&amp;#x2F;&amp;#x2F;en.wikipedia.org&amp;#x2F;wiki&amp;#x2F;Aromatic_L-amino_acid_decarboxy...&lt;/a&gt;&lt;p&gt;[1] &lt;a href=&quot;http://www.amazon.com/gp/product/B000MYW2ZA/&quot; rel=&quot;nofollow&quot;&gt;http:&amp;#x2F;&amp;#x2F;www.amazon.com&amp;#x2F;gp&amp;#x2F;product&amp;#x2F;B000MYW2ZA&amp;#x2F;&lt;/a&gt;&lt;p&gt;[2] &lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/15781732&quot; rel=&quot;nofollow&quot;&gt;http:&amp;#x2F;&amp;#x2F;www.ncbi.nlm.nih.gov&amp;#x2F;pubmed&amp;#x2F;15781732&lt;/a&gt;&lt;p&gt;[3] &lt;a href=&quot;http://examine.com/supplements/5-HTP/#summary5-1&quot; rel=&quot;nofollow&quot;&gt;http:&amp;#x2F;&amp;#x2F;examine.com&amp;#x2F;supplements&amp;#x2F;5-HTP&amp;#x2F;#summary5-1&lt;/a&gt;&lt;p&gt;[4] &lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/11374875&quot; rel=&quot;nofollow&quot;&gt;http:&amp;#x2F;&amp;#x2F;www.ncbi.nlm.nih.gov&amp;#x2F;pubmed&amp;#x2F;11374875&lt;/a&gt;</text><parent_chain></parent_chain></comment><story><title>McMaster researchers may have found a way to restore metabolism to youth levels</title><url>http://www.cbc.ca/news/canada/hamilton/news/want-to-eat-like-a-teen-again-science-may-have-found-a-way-1.2862231</url></story>