<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>gambiting</author><text>Well, yeah, steroids are incredible, shame they have such severe side effects. Following a parvovirus B19 infection I developed severe joint problems(basically got advanced arthritis at the age of 28, how fun), and all it took to sort out was one steroid injection. I won&amp;#x27;t lie, for the next few days after the injection I felt like a superhuman, all the issues went away and in general I felt super great. Obviously that&amp;#x27;s not something you can continue doing because the side effects get really bad after a while, my doctor warned me that if the issues come back I probably won&amp;#x27;t be able to get another injection because the risk is too great, but for a one-off thing it was like a miracle cure.</text><parent_chain><item><author>csomar</author><text>Dexamethasone is a serious drug and corticosteroid [1]. It was prescribed for a friend after eye-surgery and having skin &amp;#x2F; eye inflammation problems, I used it (with no doctors advice) recklessly albeit with very small quantities.&lt;p&gt;The drug was hyper-effective. An unbelievably tiny quantity can remove any inflammation (eye, skin, hair skin rash, etc...). But the fall out and side-effects are no joke even for seemingly super minuscule doses. It was a horror story for me with horrible eye inflammation, small inflammations in different parts of the body and a skin rash I still struggle with until today. Mind you I took small localized doses and not an injection. I wasn&amp;#x27;t aware that it can travel through your skin, get into your blood and make a mess.&lt;p&gt;I think the research will need to specify potential side-effects and their probabilities. It&amp;#x27;s trade-off at the end of the day.&lt;p&gt;PS: Do not ever think of trying it without medical advice and doctor supervision.&lt;p&gt;[1]: &lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;en.wikipedia.org&amp;#x2F;wiki&amp;#x2F;Dexamethasone#Adverse_effects&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;en.wikipedia.org&amp;#x2F;wiki&amp;#x2F;Dexamethasone#Adverse_effects&lt;/a&gt;</text></item></parent_chain></comment><story><title>Coronavirus: Dexamethasone proves first life-saving drug?</title><url>https://www.bbc.com/news/health-53061281</url></story>
<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>ceejayoz</author><text>To be clear, it&amp;#x27;s generally advisable to only take a prescription drug under the direction of a doctor. This isn&amp;#x27;t unique to dexamethasone.&lt;p&gt;Steroids plus eyes can lead to glaucoma. My doc won&amp;#x27;t let me use them anywhere near the face.</text><parent_chain><item><author>csomar</author><text>Dexamethasone is a serious drug and corticosteroid [1]. It was prescribed for a friend after eye-surgery and having skin &amp;#x2F; eye inflammation problems, I used it (with no doctors advice) recklessly albeit with very small quantities.&lt;p&gt;The drug was hyper-effective. An unbelievably tiny quantity can remove any inflammation (eye, skin, hair skin rash, etc...). But the fall out and side-effects are no joke even for seemingly super minuscule doses. It was a horror story for me with horrible eye inflammation, small inflammations in different parts of the body and a skin rash I still struggle with until today. Mind you I took small localized doses and not an injection. I wasn&amp;#x27;t aware that it can travel through your skin, get into your blood and make a mess.&lt;p&gt;I think the research will need to specify potential side-effects and their probabilities. It&amp;#x27;s trade-off at the end of the day.&lt;p&gt;PS: Do not ever think of trying it without medical advice and doctor supervision.&lt;p&gt;[1]: &lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;en.wikipedia.org&amp;#x2F;wiki&amp;#x2F;Dexamethasone#Adverse_effects&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;en.wikipedia.org&amp;#x2F;wiki&amp;#x2F;Dexamethasone#Adverse_effects&lt;/a&gt;</text></item></parent_chain></comment><story><title>Coronavirus: Dexamethasone proves first life-saving drug?</title><url>https://www.bbc.com/news/health-53061281</url></story>