<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>ericmcer</author><text>I hate this because I want to believe technology and AI and will result in modern medicine where everyone has long healthy lives.&lt;p&gt;The reality that just eating right, sleeping and exercising is still our best health advice  is humorous and disheartening.</text><parent_chain><item><author>personalityson</author><text>&amp;quot;Scientists researching possible candidates for treating Alzheimer&amp;#x27;s disease found exercise outperformed all tested drugs for the ability to reverse dysregulated gene expression.&amp;quot;
&lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.nature.com&amp;#x2F;articles&amp;#x2F;s41598-022-22179-z&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.nature.com&amp;#x2F;articles&amp;#x2F;s41598-022-22179-z&lt;/a&gt;&lt;p&gt;&amp;quot;High fitness in middle age reduces the chance of dementia by ninety percent&amp;quot;
&lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.ergo-log.com&amp;#x2F;high-fitness-in-middle-age-reduces-chance-of-dementia-by-ninety-percent.html&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.ergo-log.com&amp;#x2F;high-fitness-in-middle-age-reduces-...&lt;/a&gt;</text></item></parent_chain></comment><story><title>What causes Alzheimer&apos;s? Scientists are rethinking the answer</title><url>https://www.quantamagazine.org/what-causes-alzheimers-scientists-are-rethinking-the-answer-20221208/</url></story>
<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>throwawaymaths</author><text>&amp;gt; High fitness in middle age reduces the chance of dementia by ninety percent&lt;p&gt;Not to be a sourpuss but I believe that a reasonable theory on this is that physical activity, especially activity that uses brain power, causes neuronal development which reroutes function around damage, without necessarily preventing or mitigating damage itself.</text><parent_chain><item><author>personalityson</author><text>&amp;quot;Scientists researching possible candidates for treating Alzheimer&amp;#x27;s disease found exercise outperformed all tested drugs for the ability to reverse dysregulated gene expression.&amp;quot;
&lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.nature.com&amp;#x2F;articles&amp;#x2F;s41598-022-22179-z&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.nature.com&amp;#x2F;articles&amp;#x2F;s41598-022-22179-z&lt;/a&gt;&lt;p&gt;&amp;quot;High fitness in middle age reduces the chance of dementia by ninety percent&amp;quot;
&lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.ergo-log.com&amp;#x2F;high-fitness-in-middle-age-reduces-chance-of-dementia-by-ninety-percent.html&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.ergo-log.com&amp;#x2F;high-fitness-in-middle-age-reduces-...&lt;/a&gt;</text></item></parent_chain></comment><story><title>What causes Alzheimer&apos;s? Scientists are rethinking the answer</title><url>https://www.quantamagazine.org/what-causes-alzheimers-scientists-are-rethinking-the-answer-20221208/</url></story>