<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>op00to</author><text>I use an iota-carrageenan nasal spray that has clinical evidence showing it&amp;#x27;s effective at reducing the duration of common cold, as well as some protection from COVID. Obviously, the COVID research is a bit flimsier. It&amp;#x27;s also cheap, and carrageenan is pretty inert. I use it any time I&amp;#x27;m around big groups of people for more than a few minutes.&lt;p&gt;[1] common cold: &lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.ncbi.nlm.nih.gov&amp;#x2F;pmc&amp;#x2F;articles&amp;#x2F;PMC7880062&amp;#x2F;#:~:text=Therefore%2C%20all%204%20clinical%20trials,absorbed%20from%20the%20nasal%20mucosa&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.ncbi.nlm.nih.gov&amp;#x2F;pmc&amp;#x2F;articles&amp;#x2F;PMC7880062&amp;#x2F;#:~:tex...&lt;/a&gt;.
[2] covid: &lt;a href=&quot;https:&amp;#x2F;&amp;#x2F;www.ncbi.nlm.nih.gov&amp;#x2F;pmc&amp;#x2F;articles&amp;#x2F;PMC8493111&amp;#x2F;&quot; rel=&quot;nofollow&quot;&gt;https:&amp;#x2F;&amp;#x2F;www.ncbi.nlm.nih.gov&amp;#x2F;pmc&amp;#x2F;articles&amp;#x2F;PMC8493111&amp;#x2F;&lt;/a&gt;</text><parent_chain><item><author>TonyTrapp</author><text>There&amp;#x27;s already some nasal sprays around that supposedly protect against Covid-19 in a similar way. However many places online just echo the copy from the manufacturers about the efficiency. Has anyone tried those sprays and can share their experience?</text></item></parent_chain></comment><story><title>A nasal spray protects against coronavirus including immune-evasive variants</title><url>https://www.helsinki.fi/en/news/pandemics/nasal-spray-protects-against-coronavirus-infection-effective-also-against-recent-immune-evasive-variants</url></story>
<instructions>Your goal is to analyze the following comment and estimate how highly it will be upvoted by the Hacker News community.</instructions><comment><author>jedberg</author><text>If you&amp;#x27;re talking about the nitric oxide spray, my friend used it at a conference and got COVID anyway, so where n=1, it didn&amp;#x27;t work.  But then again, almost all of us got COVID.  I was masked the whole time, he used the spray, others took no preventative measures, and it didn&amp;#x27;t seem to matter much.</text><parent_chain><item><author>TonyTrapp</author><text>There&amp;#x27;s already some nasal sprays around that supposedly protect against Covid-19 in a similar way. However many places online just echo the copy from the manufacturers about the efficiency. Has anyone tried those sprays and can share their experience?</text></item></parent_chain></comment><story><title>A nasal spray protects against coronavirus including immune-evasive variants</title><url>https://www.helsinki.fi/en/news/pandemics/nasal-spray-protects-against-coronavirus-infection-effective-also-against-recent-immune-evasive-variants</url></story>