I've observed that when React's profiling mode is enabled, updating the profiling fields [here](https://github.com/facebook/react/blob/1d25aa5787d4e19704c049c3cfa985d3b5190e0d/packages/react-reconciler/src/ReactProfilerTimer.js#L46) and [here](https://github.com/facebook/react/blob/1d25aa5787d4e19704c049c3cfa985d3b5190e0d/packages/react-reconciler/src/ReactProfilerTimer.js#L69-L71) during the _render_ phase seems to cause a significant deopt in [`getHostSibling`](https://github.com/facebook/react/blob/1d25aa5787d4e19704c049c3cfa985d3b5190e0d/packages/react-reconciler/src/ReactFiberCommitWork.js#L858-L898) during the _commit_ phase for Chrome only. (Neither Safari nor Firefox seem to be affected by this.)

I have created a repro case with inline annotations here:
https://github.com/bvaughn/react-profiling-v8-deopt-repro#about-this-repro-case

(Note that the above repo is private. Please tag me here if you need access.)
this.lastEffect = null;
  this.expirationTime = NoWork;
  this.childExpirationTime = NoWork;
  this.alternate = null;
  if (enableProfilerTimer) {
    this.actualDuration = 0;
    this.actualStartTime = -1;
    this.selfBaseDuration = 0;
    this.treeBaseDuration = 0;
  }
  if (__DEV__) {
    this._debugID = debugCounter++;
    this._debugSource = null;
    this._debugOwner = null;
    this._debugIsCurrentlyTiming = false;
    if (!hasBadMapPolyfill && typeof Object.preventExtensions === 'function') {
      Object.preventExtensions(this);
    }
  }
}
const createFiber = function(
  tag: WorkTag,
  pendingProps: mixed,
  key: null | string,
  mode: TypeOfMode,
): Fiber {
  
  return new FiberNode(tag, pendingProps, key, mode);
};
function shouldConstruct(Component: Function) {