["[Dialogue between User and Assistant on 2024-01-01 00:00]\n<User>These are labeled examples for classification tasks:\n\nSample: The study included 34 patients ( 13 dersalazine sodium , 10 mesalazine , and 11 placebo ) .\n\nLabels: 4\n\nSample: Children were enrolled after a first or second UTI .\n\nLabels: 2\n\nSample: There were no grade 3 or 4 toxicities .\n\nLabels: 4\n\nSample: MTBS values were obtained using a universal testing machine ( cross-head speed = 0.5 mm/min ) .\n\nLabels: 2\n\nSample: High blood pressure is an important and modifiable cardiovascular disease risk factor that remains under-detected and under-treated .\n\nLabels: 3\n\nSample: Within-group changes and comparison between the isoflavone and casein placebo groups were determined by a mixed effects model .\n\nLabels: 2\n\nSample: They were carefully monitored , and the annual rate of recurrent ischemic stroke and major hemorrhagic complications were compared between the groups .\n\nLabels: 2\n\nSample: Within the framework of the TOMBOLA randomized controlled trial of alternative managements , 844 women aged 20 to 59 years with a single routine cytology test showing borderline nuclear abnormalities ( BNA ; broadly equivalent to atypical squamous cells of undetermined significance ) were assigned to follow-up by repeat cytology in primary care ( the first test was due 6 months after the initial BNA result ) .\n\nLabels: 2\n\nSample: For placebo nonremitters , both duloxetine ( OR = 3.52 [ 95 % CI : 2.21 , 5.62 ; P < 0.0001 ] ) and SSRIs ( OR = 2.38 [ 95 % CI : 1.45 , 3.89 ; P = 0.0006 ] ) showed significantly higher remission rates compared to placebo .\n\nLabels: 4\n\nSample: Macrolide antibiotics are active against oral anaerobic bacteria .\n\nLabels: 0\n\nSample: The aim of this study was to investigate the effect of a probiotic drink containing Lactobacillus casei Shirota ( LcS ) on immune function in a healthy non-immunocompromised older population .\n\nLabels: 3\n\nSample: Chronic constipation is a widespread condition .\n\nLabels: 0\n\nSample: Here we describe the disability , living circumstances , quality of life , and hospital costs of patients in CLOTS 3 .\n\nLabels: 0\n\nSample: There was no association between maternal recall and the level of patient-centredness demonstrated by the ` student ' .\n\nLabels: 4\n\nSample: There was no significant difference in the average number of steps between the TCC and the RCW ( 767.6 + / - 563.3 daily steps , P = 0.67 ) or the RCW and the half-shoe ( P = 0.15 ) .\n\nLabels: 4\n\nSample: After adjusting for age , HIV status , duration of prostitution , price per intercourse and condom use , and accounting for prevalence at enrollment and cluster-pairing effect , prevalence ratios ( intervention vs. placebo ) of NG infection were 0.77 ( P = NS ) , 1.07 ( P = NS ) , and 0.49 ( P = 0.05 ) at the first , second , and third follow-up visits , respectively .\n\nLabels: 4\n\nSample: There were 492 additional breast cancer events and 301 deaths occurred over a median 7.3 years ( range : 0.01-10 .8 years ) of follow-up .\n\nLabels: 4\n\nSample: To assess the efficacy of quetiapine , a recently introduced second generation antipsychotic medication , in reducing cognitive impairment in patients with schizophrenia .\n\nLabels: 3\n\nSample: LMWH can be used on an outpatient basis as a safer and more effective alternative to classical oral anticoagulant therapy for the secondary prophylaxis of selected patients with DVT .\n\nLabels: 1\n\nSample: Adjuvant treatment with docetaxel , as compared with vinorelbine , improves recurrence-free survival in women with early breast cancer .\n\nLabels: 1\n\nSample: A significant 25 % relative reduction in the albumin excretion rate occurred after 5 weeks of the 50-mg losartan dose , with further improvement over the subsequent 5 weeks with the 100-mg dose ( relative reduction , 34 % ) .\n\nLabels: 4\n\nSample: To compare outcomes of microincision cataract surgery ( MICS ) with coaxial phacoemulsification .\n\nLabels: 3\n\nSample: Multivariable analysis identified older age at diagnosis ( hazard ratio = 1.14 per year ; P < 0.001 ) , larger left ventricular ( LV ) end-diastolic M-mode dimension z-score ( hazard ratio = 1.49 ; P < 0.001 ) , and lower septal peak systolic tissue Doppler velocity z-score ( hazard ratio = 0.81 ; P = 0.01 ) as independent predictors of disease progression .\n\nLabels: 4\n\nSample: Hemodynamic values were measured at base line ( T0 ) , and then at 15 , 30 , 60 , 120 and 180 minutes after induction of general anesthesia ( T1 , T2 , T3 , T4 and T5 , respectively ) .\n\nLabels: 2\n\nSample: Five years later these individuals were invited to a second LE-MRI , and 176 of them ( 82 women , 94 men ) , who did not have a hospital diagnosis of MI , constitute the present study population .\n\nLabels: 2\n\nSample: Here we assess the effect of therapy on HRQOL and explore factors that influence the HRQOL profiles and subdomains .\n\nLabels: 3\n\nSample: Less than 3 % were using antihypertensives or statins .\n\nLabels: 4\n\nSample: Pentoxifylline suppresses the production of TNF-alpha .\n\nLabels: 0\n\nSample: The proportion of participants resuming cART before end of study and change in CD4 counts during the treatment interruption showed no benefit of vaccination .\n\nLabels: 1\n\nSample: However , due to methodological uncertainty no advice can be given regarding the implementation of the intervention in Dutch general practices .\n\nLabels: 1\n\nSample: However , a common work strategy and analysis of the data has recently been reached , and the first study results of the trial ( evaluating 180,000 men over a 10-year screening period ) are expected by the year 2007 .\n\nLabels: 4\n\nSample: Subjects having a heavier daily flow rating during the 21/7-day pre-extension cycle had greater daily flow ratings ( P < .001 ) and tended to have earlier occurrence of BTB during the extended regimen ( P = .07 ) than subjects with lighter daily flow ratings .\n\nLabels: 4\n\nSample: The surgical or chemotherapy regimen and histological type did not .\n\nLabels: 4\n\nSample: A multicenter , double-blind , randomized , clinical trial was performed .\n\nLabels: 2\n\nSample: Survival curves for the two groups did not statistically differ .\n\nLabels: 4\n\nSample: Its antioxidant and anti-inflammatory effects may help reduce the oxidative stress of the cochlea in SSNHL , implying a new direction in the treatment of this disease .\n\nLabels: 1\n\nSample: Furosemide also affected plasma and urine pharmacokinetic profiles .\n\nLabels: 1\n\nSample: Childbirth is not specifically associated with symptomatology following treatment for bulimia nervosa .\n\nLabels: 1\n\nSample: During the study lipid profile data were within the target levels .\n\nLabels: 4\n\nSample: Nineteen children ( twelve boys and seven girls with a mean age of nine years and eight months ) with spastic diplegia were enrolled .\n\nLabels: 2\n\nSample: PCT values for mesial contacts were 2.99 0.47 N for group 1 , 4.57 0.36 N for group 2 , and 3.03 0.79 N for group 3 .\n\nLabels: 4\n\nSample: One of the factors that may promote deterioration in quality of life and body composition in elderly men is the relative decline in serum testosterone levels with aging .\n\nLabels: 3\n\nSample: NT-pro-BNP level is increased in both systolic and diastolic heart failure ( HF ) and furthermore increases more during exercise .\n\nLabels: 0\n\nSample: Mean reductions in liver CC amplitude on magnetic resonance imaging and fluoroscopy were nonsignificant .\n\nLabels: 4\n\nSample: Large-scale clinical trials are required to verify these results .\n\nLabels: 1\n\nSample: Medical education experts have called for improved training in evidence-based medicine ( EBM ) and the increased use of e-learning technologies in medical education .\n\nLabels: 3\n\nSample: The present study examined the effect of orlistat on dietary intake , especially fat intake , during long-term weight maintenance .\n\nLabels: 0\n\nSample: Our treatment protocol is closed treatment for Class 1 fractures ; either closed or open treatment for Class 2 fractures ; and open treatment for Class 3 fractures .\n\nLabels: 2\n<Assistant>Got it. I will remember them.", "[Dialogue between User and Assistant on 2024-01-02 00:00]\n<User>Here are categorized examples with their respective labels:\n\nSample: This randomized trial with median followup approaching 9 years showed that cryoablation was inferior in attaining biochemical disease-free survival in patients with locally advanced prostate cancer ( cT2c-T3 ) .\n\nLabels: 1\n\nSample: Endocrine treatment with polyestradiol phosphate induced fewer and less distressing hot flashes than complete androgen ablation .\n\nLabels: 1\n\nSample: Ramosetron is a better antiemetic than granisetron for the long-term prevention of postoperative vomiting in children undergoing general anesthesia for tonsillectomy .\n\nLabels: 1\n\nSample: For difficulty with activities of daily living : those always active , 17 ( 37.8 % ) of 45 women ; those inconsistently active , 24 ( 40.0 % ) of 60 women ; and those always inactive , 39 ( 59.1 % ) of 66 women ( chi2 for trend P = .02 ) .\n\nLabels: 4\n\nSample: Early radiotherapy with concurrent chemotherapy after resection of stage II and III rectal cancer demonstrated a statistically significant advantage for disease-free survival compared with late radiotherapy with chemotherapy .\n\nLabels: 1\n\nSample: In all , 306 women ( aged 21-84 years ) were recruited and randomly assigned to placebo ( 153 ) or duloxetine ( 80-mg/day for 4 weeks increased to 120-mg/day for 8 weeks ; 153 ) .\n\nLabels: 2\n\nSample: CRITERIA FOR INCLUSION : Patients 1 month to 14 years old , who underwent some kind of manipulation or instrumentation ( mechanical ventilation , vascular cannulation , monitoring of intracranial pressure , thoracic or abdominal drainage , bladder catheterization , peritoneal dialysis , etc. ) and/or presented a neurological coma requiring a stay in the PICU of 3 or more days .\n\nLabels: 2\n\nSample: In ambroxol group ( n = 25 ) , patients were given ambroxol for a week before and after the elective coronary artery bypass grafting .\n\nLabels: 2\n\nSample: Secondary outcomes will include other gait parameters , sensorimotor and balance performances , cognitive indices , falls and fall related injury , fear of falling , Parkinson 's symptoms and data pertaining to possible harms .\n\nLabels: 2\n\nSample: This pilot study failed to demonstrate a benefit for galantamine augmentation of antidepressant medication in the treatment of depression in older adults .\n\nLabels: 1\n\nSample: Placebo-controlled studies are needed to clarify the role of atomoxetine in this population .\n\nLabels: 1\n\nSample: A total of 54 implants were placed ( 26 6 mm and 28 10 mm implants ) .\n\nLabels: 2\n\nSample: At week 144 , 146/189 ( 77 % ) versus 132/180 ( 73 % ) subjects in the unboosted ATV and ATV/r groups , respectively , maintained HIV RNA < 50 copies/mL .\n\nLabels: 4\n\nSample: Randomized trials comparing dosages and regimens of various antimicrobial agents for treatment of acute and persistent leptospirosis .\n\nLabels: 2\n\nSample: Inpatient and outpatient clinic , Breast Unit , `` San Giuseppe Moscati '' Hospital , Avellino , Italy .\n\nLabels: 2\n\nSample: The on study creatinine clearance ( CrCl ) , as estimated ( for up to 48 months ) by the Cockroft-Gault formula , was compared within and between treatment groups using analysis of variance to assess differences over time .\n\nLabels: 4\n\nSample: At monthly intervals , best-corrected visual acuity ( BCVA ) was measured and retinal morphology was assessed by standardized OCT , including intraretinal cysts ( IRCs ) , subretinal fluid ( SRF ) , and pigment epithelial detachment ( PED ) , presenting with a width 400 m or a height of 200 m. Results were correlated for each regimen , feature , and time .\n\nLabels: 2\n\nSample: Median length of stay ( 7.0 vs 5.0 days , P = .54 ) and readmission rate ( 15 % vs 4 % , P = .07 ) were not significantly higher in the elderly group .\n\nLabels: 4\n\nSample: In part A , patients received escalating doses to determine the maximum-tolerated dose ( MTD ) .\n\nLabels: 2\n\nSample: Two hundred thirty-eight patients with chronic low back disability of at least 6 months ' duration were included .\n\nLabels: 2\n\nSample: Oral famciclovir , 500 mg or 750 mg three times daily for 7 days , is an effective and well-tolerated therapy for herpes zoster that decreases the duration of the disease 's most debilitating complication , postherpetic neuralgia .\n\nLabels: 1\n\nSample: Despite considerable controversy over the inclusion of sucrose in the diets of people with diabetes , the acute metabolism of sucrose is not completely understood .\n\nLabels: 0\n\nSample: In contrast , mean long-interval intracortical inhibition ( LICI ) was increased by PGB ( 26 + / - 4 % of unconditioned response ) compared with placebo ( 45 + / - 8 % of unconditioned response ) , and mean cortical silent period ( CSP ) showed an increase from 139 + / - 8 ms or 145 + / - 8 ms after placebo to 162 + / - 7 ms or 161 + / - 10 ms after PGB .\n\nLabels: 4\n\nSample: Glucocorticoids are used in pleural tuberculosis to reduce inflammation-induced pathology , and their use also might reduce progression of HIV by suppressing immune activation .\n\nLabels: 0\n\nSample: It also includes 6 single item questions about : work status , frequency of social interactions , satisfaction with sexual relationships , days in bed , days with restricted activity and overall satisfaction with health status .\n\nLabels: 3\n\nSample: Peer services , or support provided by others who have experience in the behavioral health system , is a promising new avenue for helping those with behavioral health concerns move forward in their lives .\n\nLabels: 0\n\nSample: Supplements seemed well tolerated .\n\nLabels: 1\n<Assistant>Great! I've added this to my knowledge base.", "[Dialogue between User and Assistant on 2024-01-03 00:00]\n<User>Here are some annotated classification examples:\n\nSample: Objective cognitive impairment was assessed using a battery of 12 standardized neuropsychological measures yielding 16 indices .\n\nLabels: 2\n\nSample: All tested parameters ( ETDRS visual acuity ; computerized perimetry ; retinography ; fluorescein angiography ) , improved significantly ( p < 0.001 ) in Defibrotide-treated patients compared to controls .\n\nLabels: 4\n\nSample: Fourteen subjects completed the study and an ITT analysis ( n = 22 ) of the data showed no significant differences in WOMAC scores however , the data did reveal significant improvements in passive and active extension ROM ( 0.83 degrees + / - 1.54 vs. -1.54 degrees + / - 2.43 ; difference , 5.2 degrees + / - 2.2 , p = 0.028 ) and 6 MWD ( 150 + / - 48 ft vs. 12.5 + / - 31.5 ft ; difference , 136 + / - 57 ft , p = 0.03 ) in the Aquamin group compared to the placebo group ; respectively , following a 50 % reduction in NSAID use .\n\nLabels: 4\n\nSample: Sixty patients with an unsatisfactory colposcopy during the period of September 2007-November 2008 were recruited and randomly allocated to receive either two tablets of 200 microg misoprostol ( 400 microg ) or two tablets of similar-looking placebo vaginally .\n\nLabels: 2\n\nSample: Eighty-two patients were included , of whom 16 were included with both of their legs .\n\nLabels: 2\n\nSample: Additionally peripheral ( Aa ) blood levels of heart fatty acid binding protein ( HFABP ) , troponin T , CPK and CKMB as markers of myocardial injury were obtained .\n\nLabels: 2\n\nSample: Level I , therapeutic study .\n\nLabels: 2\n\nSample: Current guidelines in Japan recommend loxoprofen sodium ( loxoprofen ) , a pro-drug in the propionic acid class of nonselective NSAIDs , as first-line therapy in rheumatoid arthritis .\n\nLabels: 0\n\nSample: The aim of the present prospective study is to compare the safety and efficacy of propofol-ketamine versus propofol alone , managed by trained pediatricians , in children with cancer undergoing painful procedures .\n\nLabels: 0\n\nSample: The study was completed by 67 patients ( 89 % ) .\n\nLabels: 4\n\nSample: Patients tranquil or sedated at 20 minutes .\n\nLabels: 2\n\nSample: To compare the achieved refractive outcomes of patients undergoing cataract surgery with intraocular lens ( IOL ) power calculation performed by conventional immersion ultrasound ( US ) or partial coherence interferometry ( PCI ) .\n\nLabels: 3\n\nSample: To identify susceptibility markers to CysLT effects and montelukast response .\n\nLabels: 3\n\nSample: The combined intraindividual and assay/measurement residual error in everolimus blood concentrations was 31 % .\n\nLabels: 4\n\nSample: The limited curriculum time devoted to this topic may make it difficult to train physicians about complex employment issues during pregnancy .\n\nLabels: 1\n\nSample: Resistance training consisted of thrice weekly sessions of four exercises , 3-4 sets/exercise of 10-15 repetitions at 12-15 repetition maximum load .\n\nLabels: 2\n\nSample: Patients ' comfort levels were high for both treatments .\n\nLabels: 4\n\nSample: Data from this unblinded , pilot study suggest that noradrenalin is as effective and safe as terlipressin in patients with HRS .\n\nLabels: 1\n\nSample: The incidence of adverse effects was not statistically different .\n\nLabels: 1\n\nSample: At 6 hours pain scores were significantly lower for ropivacaine 0.5 % compared with saline for wound pain during mobilisation and pressure exerted to reach maximum pain tolerance .\n\nLabels: 4\n\nSample: Modified intention to treat analysis in 761 patients was performed .\n\nLabels: 4\n\nSample: Forty-five cases of elective cesarean section were randomly divided into 3 groups : no antibiotic was given ( group A ) , one antibiotic was given for three days ( group B ) , and only once antibiotic was used ( group C ) .\n\nLabels: 2\n\nSample: Visual acuity was estimated by transforming the Snellen chart readings into logMAR equivalents .\n\nLabels: 2\n\nSample: The VAS for pain , DASH score , Oxford Elbow Score , modified Mayo score , and hand grip strength all improved significantly from pre-injection to the 6-month follow-up in the PRP and CS groups .\n\nLabels: 4\n\nSample: No significant differences in the baseline characteristics were found between the two groups .\n\nLabels: 4\n\nSample: At final study visit , acetaminophen was used in 27 % and 21 % of placebo and glucosamine patients , respectively ( P = 0.40 ) , nonsteroidal antiinflammatory drugs were used in 29 % and 30 % ( P = 0.92 ) , and both were used in 20 % and 21 % ( P = 0.84 ) .\n\nLabels: 4\n\nSample: Change from CYC to CyA did not influence rate of relapses or time to relapse .\n\nLabels: 4\n\nSample: In addition , oseltamivir significantly reduced the duration of fever by 45.2 % ( p = 0.0051 ) , and the time to return to baseline health status by 5 days ( p = 0.0011 ) .\n\nLabels: 4\n\nSample: Most adverse morbid outcomes in high-risk patients undergoing major abdominal surgery are not reduced by use of combined epidural and general anaesthesia and postoperative epidural analgesia .\n\nLabels: 1\n\nSample: The purpose of this in vitro study was to evaluate how varying the water-to-powder ( WP ) ratio affects the setting expansion of white MTA ( WMTA ) and gray MTA ( GMTA ) .\n\nLabels: 0\n\nSample: We tested whether short-acting methylphenidate ( MPH ) , a drug that increases the availability of dopamine by blocking its reuptake , reduces energy intake and alters macronutrient preference and whether these effects are due to a mechanism of reduced hunger or food reinforcement .\n\nLabels: 3\n\nSample: The dosages of verapamil and procaine in V-P group and procaine group were doubled when the diagnosis of acute lung injury ( ALI ) or ARDS was confirmed .\n\nLabels: 2\n\nSample: Acutely agitated patients with schizophrenia or schizoaffective disorder treated with aripiprazole IM or haloperidol IM demonstrated similar effective and safe transition to their respective oral formulations .\n\nLabels: 1\n\nSample: These overall findings suggest that a limited bias is introduced by drug administration instructions .\n\nLabels: 1\n\nSample: Other limitations are short-term follow-up and absence of measurement of hemodynamic parameters or inflammatory mediators .\n\nLabels: 1\n\nSample: Public health initiatives have focused on opportunities for healthcare staff to deliver lifestyle advice routinely in primary and secondary care but there is no consistent approach to onward referrals and the rate of uptake of advice remains low .\n\nLabels: 0\n\nSample: At 1 year , the effects of the interaction plus booklet , and the booklet , on breast cancer awareness were largely sustained , although the interaction plus booklet remained much more effective .\n\nLabels: 4\n\nSample: Even though impact was small , results showed that when no intervention is implemented , obesity increases .\n\nLabels: 1\n\nSample: For all subjects , SBP , pulse pressure ( PP ) , and DBP were measured before treatment and at the terminal of a 6-week treatment .\n\nLabels: 2\n\nSample: The AUC of the Parsonnet score , Tu score and logistic regression for predicting likelihood of prolonged ICU stay were 0.701 , 0.689 and 0.764 , respectively .\n\nLabels: 4\n\nSample: Ejection fraction increased from 32 8 % to 47 18 % during that period .\n\nLabels: 4\n<Assistant>Got it. I will remember them.", "[Dialogue between User and Assistant on 2024-01-04 00:00]\n<User>The following classification examples include important label information:\n\nSample: Women were trained in oil application before exercise , at bedtime on exercise days ; the 12-week program included weekly group sessions with trained leaders guided by a prerecorded regimen ( allowing choice of program level ) plus 2 days of home exercise with the recorded regimen .\n\nLabels: 2\n\nSample: The odds for anemia ( < 100 g/L ) at 3 months was 7.7 ( 95 % CI 1.84-34 .9 ) times higher in the early compared to the delayed clamping group .\n\nLabels: 4\n\nSample: Further clinical trials in patients with renal impairment are warranted to define its role .\n\nLabels: 1\n\nSample: Two hundred twelve eyes were randomized to receive topical postoperative ketorolac 0.4 % four times daily ( Acular LS , Allergan ) or bromfenac 0.09 % twice daily ( Xibrom , ISTA Pharmaceuticals ) in an open label trial .\n\nLabels: 2\n\nSample: The increase in area at the stented portion was 0.4 + / - 0.8 mm2 in the CBA group and 1.2 + / - 0.5 mm2 in the PTCA group .\n\nLabels: 4\n\nSample: Cutaneous freeze injury coupled with a von Frey electronic device to assess the mechanical pain threshold is a convenient model that causes no discomfort .\n\nLabels: 1\n\nSample: All eyes were examined by corneal topography preoperatively as well as at 1 week and at 1 , 3 , and 6 months after surgery .\n\nLabels: 2\n\nSample: There was no difference in scores between guided use and self-directed use ( 10.7 marks versus 10.6 marks , p = 0.52 ) .\n\nLabels: 4\n\nSample: The impact of medical comorbidity on the efficacy and tolerability of duloxetine in elderly patients with major depressive disorder ( MDD ) was investigated in this study .\n\nLabels: 3\n\nSample: More than 70 % of children require analgesics after bilateral myringotomy and tube placement ( BMT ) .\n\nLabels: 0\n\nSample: Secondary analysis of data derived from a community-based randomized controlled trial of 430 homeless smokers .\n\nLabels: 2\n\nSample: There was no significant difference in improvement between the group randomised to the training visit and those in the control arm ( p = 0.80 ) .\n\nLabels: 4\n\nSample: GLP-1 is known to cause natriuresis in humans , but the effects on basic renal physiology are still partly unknown .\n\nLabels: 0\n\nSample: The purpose of this study was to assess the safety and efficacy of the adenosine regulating agent ( ARA ) acadesine for reducing long-term mortality among patients with post-reperfusion myocardial infarction ( MI ) .\n\nLabels: 3\n\nSample: In GnRH antagonist-treated ovarian stimulation cycles , luteal-phase GnRH agonist also increased ongoing pregnancy rate .\n\nLabels: 4\n\nSample: This study compares diagnostic test characteristics of 4 techniques for tip localization .\n\nLabels: 0\n\nSample: Primary events were registered during the study period in nine patients in the pioglitazone group and 10 patients in the non-pioglitazone group .\n\nLabels: 4\n\nSample: Outcome measures were prosthesis and implant failures , any complication , time needed to fully recover mental nerve function ( only for mandibular implants ) and patient preference .\n\nLabels: 2\n\nSample: Low complications rate in linked stent group , despite the lack of significant statistical differences , but indicate the effectiveness and success of the new technique .\n\nLabels: 1\n\nSample: We monitored 8-h nitrogen-corrected oxygen and carbon dioxide exchanges and breath hydrogen .\n\nLabels: 2\n\nSample: A total of 291 patients were enrolled at 29 sites in 9 European countries .\n\nLabels: 2\n\nSample: Vitamin E has a strong antioxidant capacity , and has been used in several ischemia-reperfusion studies .\n\nLabels: 0\n\nSample: Conversely , the probability that filgrastim strictly dominated pegfilgrastim for neutropenia ( ANC < 0.510 ( 9 ) / L ) is 5 % .\n\nLabels: 4\n\nSample: Cambodian rural health district .\n\nLabels: 2\n\nSample: Needle acupuncture resulted in modest improvement in function compared with control at 12 weeks ( -3.9 ; 95 % CI , -7.7 to -0.2 ) but was not significantly different from sham ( -1.7 ; 95 % CI , -6.1 to 2.6 ) and was not maintained at 1 year .\n\nLabels: 4\n\nSample: At the end of the first month , patients were randomized either to change to premixed insulins or to continue with self-mixed insulins for 2 months .\n\nLabels: 2\n\nSample: Secondary outcome measures were consistent with significant improvement in Osteoarthritis Research Society International responder index , HRQoL , and function .\n\nLabels: 4\n\nSample: Regular OT ( blood pressure after 5 min supine and after 2 min standing ) was carried out between 6:00 and 6:30 a.m. ; ` nocturial ' OT took place whenever the subject had to leave the bed at night to void .\n\nLabels: 2\n\nSample: Therefore , the aim of this study was to evaluate the effects of tedisamil and atenolol alone and in combination , on heart rate and QT interval duration at rest and during exercise tests .\n\nLabels: 3\n\nSample: However , patients on solifenacin plus tamsulosin vs placebo plus tamsulosin did show statistically significant reductions in urgency ( -2.18 vs -1.10 , p < 0.001 ) .\n\nLabels: 4\n\nSample: No differences in volume status and obesity at month 12 were observed , and improvements in hypervolemia were equal in both groups .\n\nLabels: 4\n\nSample: Modified intention-to-treat analyses were performed .\n\nLabels: 4\n\nSample: Perioperative hemodynamic parameters and BIS were measured , and the duration of anesthesia , operation and recovery time from anesthesia were recorded .\n\nLabels: 2\n\nSample: The 2 solutions provided similar duration of postoperative analgesia regardless of bone removal ( around 200 minutes ; P > .05 ) .\n\nLabels: 4\n\nSample: Therefore , the present study aimed to determine whether irisin concentration is increased after regular exercise training in humans .\n\nLabels: 0\n<Assistant>I've successfully recorded all of this data.", "[Dialogue between User and Assistant on 2024-01-05 00:00]\n<User>Here are some classification examples to learn from. Please pay attention to the labels:\n\nSample: During the first 24 hr postoperatively , the ITM group had improved pain control and a lower iv morphine requirement than the control group , both at rest and during deep breathing .\n\nLabels: 4\n\nSample: An unsolicited symptom , areactive edematous swelling of the whole thigh , occurred in 62 children ( 1.1 % ) , with 45 and 17 reports in groups 1 and 2 , respectively .\n\nLabels: 4\n\nSample: In a couple of studies , effective antidepressant treatment including electroconvulsive therapy led to an increase in BDNF serum levels .\n\nLabels: 0\n\nSample: We will model data using regression analysis to determine any differences between intervention and control groups .\n\nLabels: 2\n\nSample: A total of 1243 consecutive patients ( either premenopausal or postmenopausal ) surgically treated for unilateral invasive breast carcinoma with no evidence of metastases .\n\nLabels: 2\n\nSample: Blood samples were collected according to a predefined sampling schedule and up to 48.0 hours after administraton in each period .\n\nLabels: 2\n\nSample: The alpha1-adrenoceptor antagonist doxazosin has proved successful in treating patients with concurrent benign prostatic hyperplasia ( BPH ) and hypertension in short-term studies .\n\nLabels: 0\n\nSample: During the academic year 2007-08 , 106 medical students were randomized to receive either pelvic examination training by a gynecological teaching associate ( GTA ) alone or a standardized patient ( SP ) accompanied by an obstetrics and gynecology faculty member .\n\nLabels: 2\n\nSample: Baseline mean total cholesterol was 224 mg/dL ; LDL-C , 146 mg/dL ; high-density lipoprotein cholesterol , 48 mg/dL ; and triglycerides , 152 mg/dL .\n\nLabels: 2\n\nSample: Its use can significantly lower the usage of iodinated contrast and the number of selective cerebral circulation injections while not prolonging the length of the procedure or the fluoroscopy time .\n\nLabels: 1\n\nSample: A total of 3 therapy sessions of constant low-energy focused shock wave therapy was administered in weekly intervals in both groups .\n\nLabels: 2\n\nSample: A graded treadmill test was used to assess walking performance and peak physiological responses to exercise .\n\nLabels: 2\n\nSample: Prophylactic PDC , with or without dialysis , did not decrease the time to achieve a negative fluid balance after the Norwood procedure , did not alter physiological variables postoperatively , and was associated with more severe adverse events .\n\nLabels: 1\n\nSample: This study investigates the impact of a pioglitazone plus metformin therapy on biomarkers of inflammation and platelet activation in comparison to a treatment with glimepiride plus metformin .\n\nLabels: 0\n\nSample: The IABP was removed after 3.1 + / - 1.0 days in group 3 vs. 1.3 + / - 0.6 days in groups 1 and 2 , P < 0.001 .\n\nLabels: 4\n\nSample: However , whether EPA , DHA , or a combination of the 2 exerts these immunomodulatory effects is unclear .\n\nLabels: 0\n\nSample: Forty-eight men over 60 years old with decreased testosterone levels ( < or = 320 ng/dL ) comprised the study .\n\nLabels: 2\n\nSample: The test and endoscopy strategy increases endoscopy rates over usual practice in primary care .\n\nLabels: 1\n\nSample: Median survival times were 29.9 months for PCb , 26.9 for GDoc and 41.0 for Pw ( P = 0.037 ) .\n\nLabels: 4\n\nSample: Patients of stable angina pectoris treated with Radix Codonopsitis Pilosulae ( 50 cases ) or Nifedipine ( 20 cases ) were observed as well .\n\nLabels: 2\n\nSample: Methadone , with its long serum half-life ( thirty-five hours , compared with two hours for morphine ) could provide improved and prolonged pain relief .\n\nLabels: 0\n\nSample: Prospective randomized controlled trial using pre - and postintervention testing in hospitals .\n\nLabels: 2\n\nSample: Physiotherapy gymnasium and hydrotherapy pool .\n\nLabels: 2\n\nSample: Both the beta 1 Msp I marker and the beta 1 haplotype were linked with the resting rate-pressure product ( P = 0.007 and 0.003 , respectively ) , and all beta 1 markers showed linkage with the change in resting systolic blood pressure ( P = 0.00005 to 0.024 ) .\n\nLabels: 4\n\nSample: Using a cut-off of RAC over 20 % there was an 87.5 % sensitivity ( 95 % confidence interval [ CI ] : 45 % to 100 % ) and a 66.7 % specificity ( 95 % CI : 22 % to 96 % ) for an improvement in 6MWT of > 40 meters .\n\nLabels: 4\n\nSample: A multicenter randomized double-blind placebo-controlled trial .\n\nLabels: 2\n\nSample: Ropivacaine 7.5 mg/ml administered epidurally resulted in equally effective anaesthesia for Caesarean section as bupivacaine 5 mg/ml .\n\nLabels: 1\n\nSample: The effect of exercise on the plasma concentration of high-molecular weight ( HMW ) adiponectin ( i.e. the biologically active form of circulating adiponectin ) and the possible role of HMW adiponectin in mediating the exercise-induced enhancement of insulin action are not known .\n\nLabels: 3\n\nSample: Images obtained under scanning electron microscopy were analysed by three blinded examiners , and kappa statistics was used to evaluate calibration among examiners .\n\nLabels: 2\n\nSample: Children treated on protocol 87-01 received prednisone at a dose of 40 mg/m2/d ( standard risk , SR ) or 120 mg / m2/d ( high risk , HR ) ; those treated on protocol 91-01 received dexamethasone at a dose of 6 mg/m2 per day ( SR ) or 18 mg/m2 per day ( HR ) .\n\nLabels: 4\n\nSample: These differences were not statistically significant .\n\nLabels: 4\n\nSample: Fifty-three patients were randomized into 2 groups : control group ( n = 26 ) , which received calcium acetate as a phosphate binder throughout the study , and Ca-bread group ( n = 27 ) , which , after a 2-week washout period , received Ca-bread containing 2.5 % of elemental calcium ( by weight ) , which served as a phosphate binder .\n\nLabels: 2\n<Assistant>Got it. I will remember them.", "[Dialogue between User and Assistant on 2024-01-06 00:00]\n<User>I'm sharing some classification data with labels for you to learn:\n\nSample: University medical center .\n\nLabels: 2\n\nSample: Meanwhile , both intervention groups in the revised study continued to show significant gain in knowledge from baseline at 1 month ( P < .001 ) .\n\nLabels: 4\n\nSample: The maximum numbers of repetitions in each station was 12 .\n\nLabels: 2\n\nSample: The primary outcome was change in health-related quality of life and functioning ( SF-36 ) from baseline to 12 months .\n\nLabels: 2\n\nSample: Xuezhikang Capsule can inhibit the serum inflammatory factor in patients with NAFLD and hyperlipidemia .\n\nLabels: 1\n\nSample: This article also describes the steps of a double-blind trial in Ayurveda , which was hitherto considered difficult to perform .\n\nLabels: 0\n\nSample: To assess long-term golimumab efficacy/safety in patients with active psoriatic arthritis ( PsA ) .\n\nLabels: 3\n\nSample: Rates of treatment discontinuation were 18 % ( 28/157 ) in the tapentadol IR 50-mg group , 26 % ( 43/168 ) in the tapentadol IR 75-mg group , 35 % ( 60/172 ) in the oxycodone HCl IR 10-mg group , and 10 % ( 17/169 ) in the placebo group .\n\nLabels: 4\n\nSample: Transpupillary thermotherapy ( TTT ) with indocyanine green ( ICG ) dye enhancement ( TTT + ) and TTT alone were compared for safety and effectiveness as a treatment of occult subfoveal choroidal neovascularization in age-related macular degeneration .\n\nLabels: 3\n\nSample: More dislocations occurred in SL , but were counterbalanced by more lead malfunctions and excessive pacing thresholds in the JL group .\n\nLabels: 1\n\nSample: The results of our study revealed no influence of the Implant-link semi cement on the crestal bone level , regardless of the bone bed preparation technique .\n\nLabels: 4\n\nSample: Desaturation episodes were observed in two SB patients conversely to no episode during pressure support ventilation , probably because of the higher minute ventilation .\n\nLabels: 4\n\nSample: Analysis of QoL questionnaires showed overall improvement in both groups , with no significant difference between them .\n\nLabels: 4\n\nSample: These data support the use of the NEI VFQ-25 as a responsive and sensitive measure of vision-related function in neovascular AMD populations .\n\nLabels: 1\n\nSample: There were no significant differences between the 2 groups for height , weight , lean and fat mass .\n\nLabels: 4\n\nSample: In this study we compared how many participants recovered after each treatment .\n\nLabels: 0\n\nSample: To determine whether a new agent , paclitaxel , would further improve survival in NSCLC , the Eastern Cooperative Oncology Group conducted a randomized trial comparing paclitaxel plus cisplatin to a standard chemotherapy regimen consisting of cisplatin and etoposide .\n\nLabels: 3\n\nSample: There was modest evidence with respect to satiety by PPH consumption .\n\nLabels: 1\n\nSample: Gastric biopsy specimens were obtained from subjects with H. pylori-negative normal mucosa ( N = 12 ) , H. pylori-positive non-metaplastic gastritis ( N = 42 ) , H. pylori-positive intestinal metaplasia ( N = 21 ) and intestinal-type adenocarcinoma ( N = 20 ) .\n\nLabels: 2\n\nSample: The algorithm was not sensitive , however ; most subjects with fat intakes < or = 30 % of energy from fat failed to meet the behavioral criteria .\n\nLabels: 4\n\nSample: Intervention students were also more likely to believe that teens their age who engage in HIV risk behaviors are vulnerable to infection .\n\nLabels: 4\n\nSample: Subjects receiving cannabis reported improved appetite and sleep , with no significant side effects .\n\nLabels: 4\n\nSample: Intensive blood glucose control in patients with type 2 diabetes significantly increased treatment costs but substantially reduced the cost of complications and increased the time free of complications .\n\nLabels: 1\n\nSample: No difference in response to surgery was observed between the two groups at the time of evaluation , which took place , on average , 6 to 7 months after surgery .\n\nLabels: 4\n\nSample: While percentage of daytime ( 8 am-10 pm ) with intragastric pH > 4.0 on day 5 was overall similar across the groups , percentage of night-time ( 10 pm-8 am ) with intragastric pH > 4.0 was higher with the rabeprazole-ER groups ( 57.0-72 .4 % ) vs. esomeprazole 40 mg ( 32.8 % ) and rabeprazole-DR 20 mg ( 34.0 % ) .\n\nLabels: 4\n\nSample: Patients with depression use more health services than patients without depression .\n\nLabels: 0\n\nSample: Comparable findings were noted for similar actigraphic improvement criteria .\n\nLabels: 4\n\nSample: The active placebo device has a powerful effect on reported pain , which diminishes in the long-term .\n\nLabels: 1\n\nSample: Diurnal intraocular pressure ( IOP ) at 8 AM , 10 AM , and 4 PM and safety variables ( IOP was also measured at 8 PM at selected sites ) .\n\nLabels: 2\n\nSample: No patient suspended therapy because of side effects .\n\nLabels: 4\n\nSample: In group A the 24-h pH value obtained in the 6th month was higher ( p < 0.02 ) than that in the 3rd month of maintenance treatment .\n\nLabels: 4\n\nSample: A randomized , attention-controlled , two-group trial was conducted in a blackowned commercial gym with a sample of 366 predominantly healthy , obese African American women .\n\nLabels: 2\n\nSample: These findings would not support population screening for individuals at risk of social isolation with a view to averting service use by timely intervention .\n\nLabels: 1\n\nSample: In the full analysis , an increased risk of marked lung fibrosis was found again for patients who received tamoxifen simultaneously with radiotherapy ( with patients receiving radiotherapy alone as the referent , odds ratio = 2.9 ; 95 % CI = 1.3-6 .3 ; P = .007 ) .\n\nLabels: 4\n\nSample: At night , the response was slower and required a higher dose because more severe airway obstruction was present on awakening .\n\nLabels: 1\n\nSample: Combined with a model to predict fibrosis published previously , the nomogram presented here may assist in decision making for individual patients .\n\nLabels: 1\n\nSample: Secondary outcomes were prolonged and point-prevalence smoking abstinence rates at weeks 26 and 52 .\n\nLabels: 2\n\nSample: A similar trend in fibrinogen level was not statistically significant .\n\nLabels: 4\n\nSample: Married patients were 69.3 % and the most common presentation was breast lump ( s ) ( 88.5 % ) .\n\nLabels: 4\n<Assistant>Thanks for sharing. I've committed this to memory.", "[Dialogue between User and Assistant on 2024-01-07 00:00]\n<User>The following are classification examples with their corresponding labels:\n\nSample: No significant cardiac , renal , hepatic , or neurologic toxicity was observed .\n\nLabels: 4\n\nSample: Low-dose aspirin is standard treatment for prevention of cardiovascular events in at-risk patients .\n\nLabels: 3\n\nSample: Urapidil combined with phentolamine can control hypertension during extracorporeal circulation without causing hypotension .\n\nLabels: 1\n\nSample: The duration of analgesia , visual analogue scores for pain , motor blockade ( using a six-point modified Bromage scale ) , patient satisfaction scores , nausea , pruritus , heart rate , and blood pressure were recorded .\n\nLabels: 2\n\nSample: Current Controlled Trials ISRCTN15281875 .\n\nLabels: 0\n\nSample: Changes in visual acuity , recurrent retinal detachment , and incidence of complications .\n\nLabels: 2\n\nSample: In the < 800-g cohort ( n = 24 ) , glutamine-supplemented infants required fewer days on TPN ( 13 vs 21 days , p = .02 ) , had a shorter length of time to full feeds ( 8 vs 14 days , p = .03 ) , and needed less time on the ventilator ( 38 vs 47 days , p = .04 ) .\n\nLabels: 4\n\nSample: Sumatriptan 50-mg tablets were effective and generally well tolerated in the treatment of these patients presenting with migraine headaches that were self-described or physician-diagnosed as sinus headaches .\n\nLabels: 1\n\nSample: The mean time to first drink was 81.5 days .\n\nLabels: 4\n\nSample: All patients underwent staging pelvic lymphadenectomy .\n\nLabels: 0\n\nSample: Together , these findings highlight the importance of increased assessment and early intervention when these factors are present to potentially reduce treatment discontinuation and improve treatment outcomes in OEF/OIF veterans with PTSD .\n\nLabels: 1\n\nSample: The mean number of emetic events after maropitant treatment was significantly reduced compared with that after metoclopramide treatment ( P = 0.01 ) .\n\nLabels: 4\n\nSample: The mean caries increments at 21 months were 0.21 surfaces , 0.26 surfaces , 1.75 surfaces and 1.90 surfaces for the 1450 ppm F - , 500 ppm F - , placebo/1450 ppm F - , and placebo/500 ppm F - groups , respectively .\n\nLabels: 4\n\nSample: Twenty-four patients were randomized into 2 treatment groups , extensor tendon release and repair , and microtenotomy .\n\nLabels: 2\n\nSample: A small decrease in collagen-induced platelet aggregation was observed after administration of piroxicam alone or piroxicam + fondaparinux sodium .\n\nLabels: 1\n\nSample: This study is registered with ClinicalTrials.gov , number NCT00143598 , and Current Controlled Trials , number ISRCTN71334751 .\n\nLabels: 2\n\nSample: The number of patients who felt no pain ( VAS = 0 ) was higher with the flapless procedure ( 43 % at DO versus 20 % ) .\n\nLabels: 4\n\nSample: The total effective rate ( TBil + PTa ) was 90 % in the NAC group and 69 % in the placebo group .\n\nLabels: 4\n\nSample: Third , UK patients with no visible residual disease had a less favorable PFS compared with patients recruited from non-UK centers who were similarly debulked ( hazard ratio = 1.85 ; 95 % CI , 1.16 to 2.97 ; P = .010 ) .\n\nLabels: 4\n\nSample: Medical therapy , the cornerstone of managing epilepsy , still fails a substantial portion of patients .\n\nLabels: 0\n\nSample: A1c , body weight , and urinary glucose were compared between the two patient populations .\n\nLabels: 2\n\nSample: Fish in this study did not have overt clinical signs of nephrotoxicosis , but sustained massive tubular necrosis when given the exact therapeutic dose that has been used for channel catfish .\n\nLabels: 1\n\nSample: Bupropion SR in combination with counselling increased the abstinence rate compared with placebo , and was well tolerated .\n\nLabels: 1\n\nSample: Influenza vaccine was immunogenic in HIV-uninfected and HIV-infected pregnant women and provided partial protection against confirmed influenza in both groups of women and in infants who were not exposed to HIV .\n\nLabels: 1\n\nSample: Illness associated with bathing in marine waters contaminated with domestic sewage can no longer be viewed as minor , and indeed can have a substantial impact on the public health .\n\nLabels: 1\n\nSample: Intubation was attempted at 80 % first twitch depression of train-of-four .\n\nLabels: 4\n\nSample: Patients in both groups had significant improvement in all clinical symptoms .\n\nLabels: 4\n\nSample: All statistical tests will be performed with intention to treat .\n\nLabels: 2\n\nSample: Research is needed to replicate these findings and determine whether the antinociceptive effect of venlafaxine XR generalizes to persons with SCI pain without MDD .\n\nLabels: 1\n\nSample: The restorations were evaluated at baseline , and after 12 months using the modified USPHS criteria .\n\nLabels: 2\n\nSample: To compare the efficacy of Thio-tepa and Mitomycine C to obviate recurrence ; to compare cost-efficacy ratios ; to evaluate their facility of use and their complications .\n\nLabels: 3\n\nSample: The overall mean complaint score was significantly higher in the Spacelabs group than in the I.E.M group ( 2.24 vs. 1.78 ; P < 0.001 ) .\n\nLabels: 4\n\nSample: We conducted a randomized dispatch-assisted CPR simulation trial .\n\nLabels: 2\n\nSample: Our data indicated : ( a ) on average , the early-onset group experienced consistently more depressive symptoms than the adult-onset group ; ( b ) the pattern of symptoms remained level for both groups during the 2-year follow-up ; ( c ) both groups maintained parallel and stable course profiles over the 2-year follow-up ; and , ( d ) early age of onset was associated with higher rate of depressive relapse .\n\nLabels: 4\n\nSample: There were more adverse events experienced in the CLD group , with odds ratios of 1.9 for nausea ( 95 % confidence interval [ CI ] 1.0 - 3.6 ) , 3.8 for vomiting ( 95 % CI 1.3 - 11.3 ) , and 3.0 for headache ( 95 % CI 1.5 - 5.9 ) .\n\nLabels: 4\n\nSample: We measured serum levels of sIL-2R in 37 patients with CHC before and after treatment with recombinant interferon-alpha .\n\nLabels: 2\n\nSample: All subjects were tested on the FDP full-threshold C-20 program and the Humphrey Field Analyzer ( HFA ; Humphrey , Dublin , CA ) full-threshold program on one randomly selected eye .\n\nLabels: 2\n\nSample: DCBT1234-Lung KR was equivalent , if not better than the present day treatment with salbutamol , theophylline and bromhexine combination in COPD patients and this was ascertained using FEV1 and ABG values .\n\nLabels: 1\n\nSample: After 12 weeks , CoQ10-treated patients had significant increase in SOD activity ( p = 0.013 ) ; and decrease in MDA levels ( P = 0.003 ) compared with controls .\n\nLabels: 4\n\nSample: These results demonstrate that increasing the inorganic phosphorus content of the TPN formula decreases urinary calcium excretion by increasing renal tubular calcium resorption .\n\nLabels: 1\n\nSample: Boluses commenced from the onset of pain and continued for > 48 h as required ( pro re nata , PRN ) up to every hour for a numerical rating pain score ( NRPS , 0-10 ) > 2 .\n\nLabels: 2\n\nSample: To see whether telling peer reviewers that their signed reviews of original research papers might be posted on the BMJ 's website would affect the quality of their reviews .\n\nLabels: 3\n\nSample: Fourteen healthy subjects ( six men , mean age 23 + / - 1 ) underwent gastric emptying studies twice using the 14C octanoic acid and 13C glycin breath test after pre-treatment with saline or sumatriptan 6 mg s.c. Breath samples were taken before meal and at 15-min intervals for a period of 360 min postprandially .\n\nLabels: 2\n\nSample: The treatment group remained on aspirin and clopidogrel therapy till surgery , receiving intraoperative aprotinin .\n\nLabels: 2\n\nSample: Pharmacists provided recommendations in 148/706 ( 21.0 % ) therapies with 83.1 % acceptance .\n\nLabels: 4\n\nSample: Seventy-six people living with HIV who were actively taking ART and reported distress from ART-related side effects were randomly assigned to an MBSR program or a wait-list control ( WLC ) standard care condition .\n\nLabels: 2\n\nSample: Summary quality was similar ( mean rating 72.7 [ standard deviation ( SD ) 19.3 ] v. 74.9 [ SD 16.6 ] ) , as were assessments of completeness ( 73.4 [ SD 19.8 ] v. 78.2 [ SD 14.9 ] ) , organization ( 77.4 [ SD 16.3 ] v. 79.3 [ SD 17.2 ] ) and timeliness ( 70.3 [ SD 21.9 ] v. 66.2 [ SD 25.6 ] ) .\n\nLabels: 4\n\nSample: Prior to cementation the fit of both crowns was clinically evaluated by two calibrated and blinded examiners ; the marginal fit was also scored from replicas .\n\nLabels: 2\n<Assistant>Great! I've added this to my knowledge base.", "[Dialogue between User and Assistant on 2024-01-08 00:00]\n<User>Here are training examples for classification. Note the labels carefully:\n\nSample: Forty patients who were ASA I-II , between 18-50 years old , and who were scheduled for mastoidectomy operation were included in the study .\n\nLabels: 2\n\nSample: Substantial EPS ( defined as EPS requiring a dosage adjustment or use of medication to reduce EPS ) occurred less often with quetiapine ( median dosage , 200 mg/day ) than with risperidone ( median dosage , 3 mg/day ) ; odds ratio , 0.31 ( P < 0.03 ) .\n\nLabels: 4\n\nSample: Handling characteristics , surgical outcomes , Young 's modulus reduction , morphologic changes by scanning electron microscope , and saliva absorption test were analyzed .\n\nLabels: 2\n\nSample: This study compares moderators of initiation and maintenance of health behavior changes .\n\nLabels: 3\n\nSample: In these elderly patients with mixed dyslipidemia , R 5 , 10 , or 20 mg in combination with FA 135 mg improved the overall lipid profile , without new or unexpected safety issues .\n\nLabels: 1\n\nSample: One hundred eighty-eight nonsmoking men , aged 40 to 59 years , with prior coronary artery bypass graft surgery were randomized to colestipol/niacin plus diet therapy or placebo plus diet therapy .\n\nLabels: 2\n\nSample: Energy intake was increased at 6 months within the nutrition group ( P = .04 ) , but not the observation group , and TEE was not statistically different within either group at 6 months .\n\nLabels: 4\n\nSample: Subjects included 20 women and men ( 29.156.98 years of age , with a range of 18-47 years ) .\n\nLabels: 2\n\nSample: The course of treatment of the third group was significantly shorter than other groups , and the simultaneous symptoms occurred rarely .\n\nLabels: 1\n\nSample: Reproducibility assessment included calculation of the concordance correlation coefficient ( CCC ) .\n\nLabels: 2\n\nSample: Each patient 's outcome was evaluated 3 years after treatment by using Glasgow Outcome Scale .\n\nLabels: 2\n\nSample: Methacholine bronchial provocation test results improved significant in the active group ( P < .05 ) .\n\nLabels: 4\n\nSample: The study included 48 healthy volunteers ( 24 men , 24 women ) and used a double-blind , placebo-controlled , within-subjects design .\n\nLabels: 2\n\nSample: Fatal and nonfatal CHD and mortality .\n\nLabels: 2\n\nSample: Our results confirm that the high success rate obtained with both stents in randomized trials can be replicated in routine clinical practice .\n\nLabels: 1\n\nSample: Nine serious adverse events were reported in seven cases of which none were related to vaccines .\n\nLabels: 4\n\nSample: To test whether a preliminary in vitro susceptibility test of H. pylori to tinidazole and clarithromycin and a consequent specific regimen could improve the eradication rate .\n\nLabels: 3\n\nSample: Secondary outcome parameters include time to ADPKD-associated complications ( kidney function decrease , blood pressure control , renal pain , and albuminuria ) and safety end points .\n\nLabels: 2\n\nSample: com , number ISRCTN81456894 .\n\nLabels: 2\n\nSample: On average , verteporfin-treated patients received five treatments over the 24 months of follow-up .\n\nLabels: 4\n\nSample: Eighty-one patients with acute ischemic stroke participated in this double-blind , placebo-controlled , randomized trial of atorvastatin ( 80 mg ) vs. placebo , and/or irbesartan ( 150 mg ) vs. placebo .\n\nLabels: 2\n\nSample: There were no significant differences between the two groups in the mean ( 6 SD ) age ( 58.34 + / - 34.72 vs 66.04 + / - 36.45 months ) , arterial oxygen saturation ( 95.49 + / - 1.93 vs 95.56 + / - 1.97 ) or pulmonary score ( 4.04 + / - 1.55 vs 3.97 + / - 1.51 ) at recruitment and after treatment in the emergency department ( arterial oxygen saturation [ 96.34 + / - 1.60 vs 96.18 + / - 1.77 ] , pulmonary score [ 1.87 + / - 1.33 vs 1.64 + / - 1.31 ] ) .\n\nLabels: 4\n\nSample: All rabbits underwent an L5-L6 intertransverse process fusion with autogenous iliac crest bone graft .\n\nLabels: 2\n\nSample: There was no effect on the PDs of the ASA component : the extent of ASA inhibition of arachidonic acid-induced platelet aggregation was almost identical with and without omeprazole , with a percent mean ratio for treatment D versus A = 99.02 ( 90 % CI 98.32-99 .72 ) at 4 h after last dose .\n\nLabels: 4\n\nSample: This study demonstrated that participants in the VR integrated training group ( VR50 ) performed as well as , and in some cases , significantly outperformed , the traditional welding ( TW ) training group.The VR50 group was found to have a 41.6 % increase in overall certifications earned compared with the TW group .\n\nLabels: 4\n\nSample: In one of these patients , a perforation of the sinus membrane occurred .\n\nLabels: 4\n\nSample: Reported adherence was not associated with the type of treatment ( P = 0.73 ) but was better in children with private insurance ( P = 0.01 ) and for children with mothers reporting lower levels of parenting stress ( P = 0.03 ) .\n\nLabels: 4\n\nSample: Adverse effects were evaluated by a parent-rated questionnaire , weight , pulse and blood pressure .\n\nLabels: 2\n\nSample: The aim of this study was to investigate any pharmacokinetic interactions between eperisone hydrochloride and aceclofenac in healthy Korean men .\n\nLabels: 3\n\nSample: 4104 men and women , healthy heavy smokers/former smokers were randomised to five annual low-dose CT screenings or no screening .\n\nLabels: 2\n<Assistant>I've captured all of this valuable information.", "[Dialogue between User and Assistant on 2024-01-09 00:00]\n<User>The following are classification examples with their corresponding labels:\n\nSample: Secondary endpoints included the development of sepsis and severe sepsis during the ICU stay , the ICU length of stay , the hospital length of stay , and the duration of mechanical ventilation .\n\nLabels: 2\n\nSample: Uncertainty surrounding the incremental cost-effectiveness ratio ( difference in costs divided by difference in effects ) was calculated by bootstrapping from the original data .\n\nLabels: 2\n\nSample: This study confirms the good psychometric characteristics of Kessler 's psychological distress scale .\n\nLabels: 1\n\nSample: The difference between cleaning the teeth with cleaning brushes and additional cleaning with airflow before DIAGNOdent measurement was not statistically different ( P > 0.05 ; Wilcoxon signed-rank test ) .\n\nLabels: 4\n\nSample: In this randomized , single-blind , parallel group study , 32 healthy male volunteers received single oral doses of GI198745 ranging from 0.01 to 40 mg .\n\nLabels: 2\n\nSample: The relative odds for stroke was 1.91 for patients with hypertension , 1.73 for patients older than 75 years , and 3.26 for patients with both factors .\n\nLabels: 4\n\nSample: Both arms showed similar chemotherapy duration ( 3.8 and 4.1 months , respectively ) , progression-free survival ( 4.0 and 4.1 months ) and overall survival ( 9.9 and 9.3 months ) .\n\nLabels: 4\n\nSample: General practitioners appeared to operate enthusiast bias ' and issued more self-management plans to patients with uncontrolled asthma .\n\nLabels: 1\n\nSample: Two groups of pediatric house officers at the University of California Davis Health System completed a Maslach Burnout Survey ( MBS ) at the beginning and end of a three-month period in 2003 .\n\nLabels: 2\n\nSample: Compared with PAs in the control group , PAs who took the Web course elicited more complete family histories ( 7.2 vs 5.0 of a 13-member pedigree ; t = 2.3 , P < .05 ) and more detailed cancer histories ( 3.2 vs 2.3 of five affected family members ; t = 2.7 , P < .001 ) but did not make more genetics referrals .\n\nLabels: 4\n\nSample: This study investigated the number of spectral channels-or different pitches-that could be resolved by adult users of the CII and HiRes 90K cochlear implants when current steering was applied to three pairs of electrodes along the implanted array .\n\nLabels: 3\n\nSample: Angiotensin-converting enzyme inhibitors are a safe and effective form of treatment for erythrocytosis developing after renal transplantation .\n\nLabels: 1\n\nSample: The extruded TTs that could be collected from ears of some study patients were imaged with scanning electron microscopy ( SEM ) .\n\nLabels: 2\n\nSample: Endometrial thickness measured by transvaginal ultrasound scan increased slightly during the first year with tibolone and conjugated equine estrogen/medroxyprogesterone acetate , without any further progression .\n\nLabels: 4\n\nSample: We analyzed the long-term results of a Childrens Cancer Group ( CCG ) randomized study comparing cyclophosphamide , vincristine , methotrexate , and prednisone ( COMP ) versus LSA2L2 as treatment for childhood non-Hodgkin 's lymphoma .\n\nLabels: 3\n\nSample: Patients with 1 % to 79 % suppression were randomly assigned to the drug or its placebo that best treated their arrhythmia and followed every 4 months .\n\nLabels: 2\n\nSample: Three menstrual cycles were required .\n\nLabels: 2\n\nSample: In the intervention clusters , Aedes control was carried out using a community-based environmental management approach like provision of water container covers through community actors , clean-up campaigns , and dissemination of dengue information through schoolchildren .\n\nLabels: 2\n\nSample: Serum and blood lymphocytes were obtained regularly for 6 months .\n\nLabels: 2\n\nSample: Although zidovudine prophylaxis decreases the rate of transmission of the human immunodeficiency virus ( HIV ) type 1 substantially , a large number of infants still become infected .\n\nLabels: 0\n\nSample: Specific immunotherapy inhibits allergen-induced nasal eosinophilia .\n\nLabels: 0\n\nSample: The severity of cognitive impairment was T = 24.7 ( SD = 12.1 ) at screening and T = 26.7 ( SD = 12.4 ) at baseline .\n\nLabels: 4\n\nSample: Those with persistent limiting symptoms were offered the opportunity to participate in a trial of cognitive behavioural therapy .\n\nLabels: 2\n\nSample: The PORTAS-3 trial is designed as a multicentre , randomised controlled trial to compare two implantation strategies .\n\nLabels: 2\n\nSample: Forty-five consecutive patients were randomised to receive levosimendan in addition to the conventional therapy , its infusion starting in the operating theatre ( Group OT ) or in the ICU ( Group ICU ) when low-output syndrome was certified and were consequently dependent on classical inotropic support and IABP .\n\nLabels: 2\n\nSample: There were no differences in diarrheal outcomes , and all groups had significant weight gain .\n\nLabels: 4\n\nSample: The control group received standard treatment .\n\nLabels: 2\n\nSample: The mean ( standard deviation ) age was 50.4 ( 10.9 ) years ; most patients were female ( 64.4 % ) and white ( 77.7 % ) .\n\nLabels: 4\n\nSample: In acute cardiogenic pulmonary oedema ( ACPE ) , continuous positive airway pressure ( CPAP ) added to medical treatment improves outcome .\n\nLabels: 3\n\nSample: There are no pharmacokinetic grounds to deter co-administration of an MAOI-A and subcutaneous sumatriptan .\n\nLabels: 1\n\nSample: Statistically significantly more patients treated with 20 % ALA than with 15 % or 10 % ALA achieved complete clearance .\n\nLabels: 4\n\nSample: Intention-to-treat analysis showed a significant difference between GMT and SC on QoL and spirituality .\n\nLabels: 4\n\nSample: A significant reduction of MACCE rate in patients with the preoperative IABP counterpulsation in comparison to controls was noticed in the total population of high risk patients ( p = 0.001 ) and in the female subgroup ( p = 0.005 ) .\n\nLabels: 4\n\nSample: These changes are associated with a tendency towards shorter length of hospital stay .\n\nLabels: 1\n\nSample: MAS-XR elicits greater improvements than atomoxetine in each domain within 3 weeks of treatment , including attention , number of math problems attempted and correct , and overall clinical functioning .\n\nLabels: 4\n\nSample: However , individual susceptibility to protection was evident since some individuals were not protected at any time .\n\nLabels: 1\n<Assistant>Thanks for letting me know. I'll keep track of this.", "[Dialogue between User and Assistant on 2024-01-10 00:00]\n<User>Here are some classification examples to learn from. Please pay attention to the labels:\n\nSample: Total bleeds were significantly lower with ximelagatran compared with warfarin in elderly ( 40 % vs 45 % , P = 0.01 ) and younger ( 27 % vs 35 % , P < 0.001 ) patients .\n\nLabels: 4\n\nSample: Enhanced parent-child interactions were found to partially mediate relations between VIP and media exposure for families with a ninth grade or higher literacy level ( Sobel statistic = 2.49 ; P = .01 ) .\n\nLabels: 4\n\nSample: Video images were obtained and 12 anaesthetists rated a random selection of images .\n\nLabels: 2\n\nSample: gov number NCT 00789997 .\n\nLabels: 4\n\nSample: Analysis revealed that a scaling factor had to be used to balance the actual content differences between test products .\n\nLabels: 2\n\nSample: Chi-square , t tests , and analyses of variance and covariance .\n\nLabels: 2\n\nSample: TCA and SMR did not differ significantly concerning the reduction of myocardial ischemic load 6 months after the procedure .\n\nLabels: 1\n\nSample: Increases in muscle strength of the weight trainers were significant for all seven exercises ( 5 % -65 % ) , with the greatest gains in the shoulder and trunk muscles .\n\nLabels: 4\n\nSample: The majority of patients ( 62.2 % ) who received glimepiride achieved an HbA ( 1c ) value of < or = 7 % , compared with 26.0 % of patients receiving placebo ( P < 0.001 between groups ) .\n\nLabels: 4\n\nSample: eighty-nine patients were randomized into 2 groups using a random number table .\n\nLabels: 2\n\nSample: In this double-blind , randomized , controlled intervention trial , 144 female participants were supplemented daily with 400 micro g folic acid , 416 micro g [ 6S ] -5 - MTHF , 208 micro g [ 6S ] -5 - MTHF , or placebo .\n\nLabels: 2\n\nSample: Rotavirus is a leading cause of childhood gastroenteritis and death worldwide .\n\nLabels: 0\n\nSample: Patients , nurses , and physicians were satisfied with intervention procedures .\n\nLabels: 4\n\nSample: We analyzed outcomes and baseline characteristics of 11,975 nonsmokers , 11,117 ex-smokers and 17,507 current smokers in a multinational trial of thrombolysis for acute myocardial infarction .\n\nLabels: 0\n\nSample: The aim of this study was to establish whether glibenclamide , a selective KATP channel blocker , abolishes the ischemic preconditioning observed in humans during coronary angioplasty following repeated balloon inflations .\n\nLabels: 0\n\nSample: Consistent with the VAS score results , the Enamel Care group had respective statistically significant STSS score reductions of 77 % and 58 % greater than the control group ( p < 0.0001 ) .\n\nLabels: 4\n\nSample: Effect sizes between the subgroups `` Feeling like anyone else '' and `` Feeling almost like others '' and the group `` Feeling different '' were large for all dimensions ( 1.04-2 .07 ) .\n\nLabels: 2\n\nSample: In vitro fertilization or GIFT cycles with or without preparation ( pituitary suppression ) by GnRH-a administration in which suppression was continued or halted as gonadotropins were begun .\n\nLabels: 2\n\nSample: Analyses were performed on an intention-to-treat basis .\n\nLabels: 2\n\nSample: Unprovoked pain was measured hourly .\n\nLabels: 4\n\nSample: Two trials compared the effects of different MCT parameters on pain and function , grip strength , and sonographically graded tendon structure and hyperaemia .\n\nLabels: 2\n\nSample: Other end points were 70 % ACR responses at 3 and 6 months and other measures of disease activity at 3 and 6 months .\n\nLabels: 2\n\nSample: The incidence of complications was higher with combination treatment .\n\nLabels: 4\n\nSample: This study is registered , number ISRCTN 16571884 .\n\nLabels: 2\n\nSample: Endoscopic vein harvesting ( EVH ) is a widely accepted technique for coronary artery bypass grafting , with well-reported benefits .\n\nLabels: 0\n\nSample: The ratio of TXB2/6-K-PGF 1alpha and ST elevation were significantly higher in Group N than in Group D ( P < 0.01 ) .\n\nLabels: 4\n\nSample: Limiting the analysis to those treatments that were interrupted for filter clotting yielded similar results : 14.4 8.2 h for the AN69 ST membrane ( n = 62 ) versus 14.1 7.5 h for the original AN69 membrane ( n = 56 ) ( p = 0.93 ) .\n\nLabels: 4\n\nSample: WOMAC scores improved in all 3 groups over time , with no significant differences among groups .\n\nLabels: 4\n\nSample: The study was two limb , randomized , and single-blind .\n\nLabels: 2\n\nSample: In cases where coecal intubation is not obtained , conversion to examination with fluoroscopy should be possible .\n\nLabels: 1\n\nSample: To establish the efficacy of low-level laser therapy for tinnitus .\n\nLabels: 3\n\nSample: Both approaches were successful in controlling reflux .\n\nLabels: 4\n\nSample: Participants received 3 doses of outer-membrane protein ( OMP ) meningococcal vaccine developed in either Cuba or Norway or a control vaccine , with each dose given 2 months apart .\n\nLabels: 2\n\nSample: Its definite reason is unknown .\n\nLabels: 3\n\nSample: Repeated adenosine monophosphate ( AMP ) challenges are used to assess drug efficacy in clinical trials of mild , steroid-naive asthmatics .\n\nLabels: 3\n\nSample: Patients with borderline personality disorder respond to structured treatments in an outpatient setting with change in multiple domains of outcome .\n\nLabels: 1\n\nSample: In both groups , HA/migraine days decreased and MIDAS and HIT-6 scores improved .\n\nLabels: 4\n\nSample: House dust mite avoidance measures and dietary fatty acid modification , as implemented in this trial during infancy and early childhood , did not prevent the onset of asthma , eczema , or atopy in high-risk children .\n\nLabels: 1\n\nSample: As a society , improving the health of people throughout longer lives is a major public health goal .\n\nLabels: 0\n\nSample: A two-year SDD regimen in postmenopausal women significantly reduced the serum inflammatory biomarkers hs-CRP and MMP-9 and , among women more than five years postmenopausal , increased the HDL cholesterol level .\n\nLabels: 1\n\nSample: A total of 3 adverse events were reported in 2 subjects receiving ivabradine ; both fully recovered without sequelae .\n\nLabels: 4\n\nSample: Exercise occurred in participant-preferred locations ( eg , home , recreation center ) , with physiological data collected at a university-based exercise laboratory .\n\nLabels: 2\n\nSample: At the time of expected telithromycin maximum concentration , several electrocardiographic recordings were obtained at rest and during the course of a submaximal exercise test .\n\nLabels: 2\n\nSample: At week 24 , the adjusted mean changes in sitting DBP ( 24 hours postdose ) from baseline were -12.0 mm Hg [ 95 % confidence interval ( CI ) -1 0.4 to -13.6 ] in patients treated with candesartan cilexetil and -11.4 mm Hg ( 95 % CI -9.3 to -13.6 ) in patients treated with HCTZ .\n\nLabels: 4\n\nSample: Serum proprotein convertase subtilisin/kexin 9 ( PCSK9 ) binds to low-density lipoprotein ( LDL ) receptors , increasing the degradation of LDL receptors and reducing the rate at which LDL cholesterol is removed from the circulation .\n\nLabels: 0\n\nSample: Education has been advocated as an effective injury prevention intervention .\n\nLabels: 0\n\nSample: To compare the effect of nebulized racemic epinephrine to nebulized racemic albuterol on successful discharge from the emergency department ( ED ) .\n\nLabels: 3\n\nSample: Long-term S ( + ) - ketamine treatment is effective in causing pain relief in CRPS-1 patients with analgesia outlasting the treatment period by 50 days .\n\nLabels: 1\n\nSample: In trying to find an `` ideal '' relaxant we compared the relative potency of these drugs , and also measured pH , PaCO2 and skin temperature .\n\nLabels: 0\n\nSample: The NT-proB-type natriuretic peptide was analyzed at least three time points in 1,216 patients .\n\nLabels: 2\n\nSample: The costs for TEP were 2,428 Euros , 440 Euros more than for the Lichtenstein operation .\n\nLabels: 4\n\nSample: With the modified leaflet the odds ratio of successfully answering more than 70 % of questions was 13.5 ( 95 % confidence interval , 10.5-17 .5 ) compared with the unmodified leaflet .\n\nLabels: 4\n\nSample: There was no significant difference between groups in VAS scores , GH levels , blood levels of morphine and adverse effects .\n\nLabels: 4\n\nSample: Concerning the long-term efficacy , the paraplegia-triple-needling combined with the rehabilitation training achieves better result .\n\nLabels: 1\n\nSample: Within one health and social care managerial area in Northern Ireland .\n\nLabels: 2\n<Assistant>Perfect. I've stored this information in my memory."]
[{"question": "Sentence: Eighty-nine patients were randomized and received the study drug , 94 % completed the study , and 98 % were compliant with dosing .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Patients with neutropenia resulting from chemotherapy for acute myelogenous leukemia or the myelodysplastic syndrome are at high risk for difficult-to-treat and often fatal invasive fungal infections .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Patients with stroke with > or = 30 apnoeas and hypopnoeas per hour ( ( A+H ) / h ) with predominant obstructive sleep apnoea or hypopnoea were randomised to either CPAP treatment or conservative treatment for 8 weeks .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: NaP was better tolerated than PEG ( p < 0.001 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: We performed a prospective , double-blind , randomized , placebo-controlled study comparing intraoperative infiltration of 20 mililiters of bupivacaine ( treatment , group B ) versus saline ( placebo ) , with Gelfoam ( ) soaked into the iliac crest harvest site for patients undergoing elective cervical spinal surgery .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: To evaluate radiographic progression in patients with ankylosing spondylitis ( AS ) receiving two different doses of the tumour necrosis factor antagonist golimumab .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: The diagnosis of H. pylori infection depends on the timing of biopsies in relation to the beginning of proton-pump inhibitor treatment .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Randomized , controlled trial of 208 patients aged 65 years or older with polypharmacy ( > or = 5 chronic medications ) from a general medicine clinic of a Veterans Affairs Medical Center .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Both misoprostol and surgical evacuation are highly effective treatments for incomplete abortion ( misoprostol : 94.4 % , surgical : 100.0 % ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Coprimary end points are MACCE and stent thrombosis .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: A higher proportion of the intervention group than of the control group had a clinically relevant reduction of 70 % or more in the frequency of all incontinence episodes ( P < 0.001 ) , stress-incontinence episodes ( P = 0.009 ) , and urge-incontinence episodes ( P = 0.04 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: 195 irritable bowel syndrome with constipation patients received daily doses of 16 [ 8 microg twice daily ( b.d. ) ] , 32 ( 16 microg b.d. ) or 48 microg ( 24 microg b.d. ) lubiprostone or placebo b.d. for 3 months .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Primary outcomes including recurrent ischemic stroke , neurologic deterioration , periphery vascular events , and myocardial infarction were monitored .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Antiplatelet therapy plays a pivotal role in contemporary percutaneous coronary interventions ( PCI ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Nifedipine GITS caused only minor changes in plasma renin activity and plasma angiotensin II in young and older patients .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: RBC velocity tended to increase during CO inhalation ( +8 + / - 22 % ) , but this effect did not reach the level of significance ( P = 0.1 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: A significant reduction of anxiety compared with the placebo control was seen after a week 's treatment with Kavosporal forte , levels of anxiety being measured a priori from the combined scores of two self-rating scales and one observer-rated scale .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The WML burden and the effect of agalsidase beta 1 mg/kg biweekly on WML progression were assessed longitudinally in a Phase 4 agalsidase-beta placebo-controlled analysis of untreated and treated FD patients with mild-to-moderate renal involvement ( serum creatinine measurements of 1.2 mg/dl and < 3.0 mg/dl ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: At week 4 and subsequently , significantly more patients in the epoetin alfa group did not have RBV dosage reductions ( p < 0.011 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Safety data were evaluated up to 30 days after the last dose of medication .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Furthermore , intensity and time course of local reactions seemed to depend on the concentration of mistletoe lectins in those extracts .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Four hundred thirteen patients undergoing IVF .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: In this study , we compared the analgesia and side effects of a continuous infusion of ropivacaine 0.2 % and 0.3 % administered through an interscalene catheter for the first 48 hours after surgery .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Elderly persons often experience a reduced immune response to influenza vaccination .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Empiric therapy with cefdinir appears to be a reasonable choice for patients with uncomplicated urinary tract infection in whom cephalosporin treatment is indicated .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: However , the effects on reducing the size of the ovarian endometrial cyst and the size of uterus with adenomyosis are not significant .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: The subjects in the exercise group performed exercise with a bicycle ergometer in the supine position 1 h/d during bed rest .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Of these , 18 were followed up with funduscopy , gonioscopy , repeat measurement of intraocular pressure and visual field assessment .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Twenty-eight patients presenting with stage IIIB non-small cell carcinoma-were included into the CEBI 142 trial since January 1993 .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: The mean area under the curve from zero to infinitum ( AUC0-infinity ) for 1-hyoscyamine was 1.862 + / -0.580 microg/L x hr after intravenous , and 1.092 + / -0.381 microl/L x hr after ocular administration ( mean + / - sd , n = 6 ) , respectively .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: This study was designed to assess differences between lateral internal anal sphincterotomy and anal advancement flap for chronic anal fissure .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: This study provides good evidence that injection of absolute ethanol , multipolar electrocoagulation ( BICAP ) and Nd-YAG laser are equally safe and effective in the endoscopic therapy of acute bleeding peptic ulcers .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: A randomized controlled trial involving 604 employees covered by a managed behavioral health plan were identified in a 2-stage screening process as having significant depression .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Therapy that is effective in lowering intraocular pressure and free of adverse effects would be expected to be beneficial in patients who are at risk of disease progression .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Half of 1062 healthy infants were randomized at 7 months of age to the intervention group ( n = 540 ) to receive at 1 - to 6-month intervals individualized dietary counseling aimed at reducing their exposure to atherosclerosis risk factors .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: In comparison with the PLMA , PAx insertion time is longer and the ventilatory characteristics of this new device may be marginally inferior .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: We undertook a multicentre , open-label , randomised controlled trial at seven specialist ALS and respiratory centres in the UK .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Ineffective efforts ( IEs ) were similar among the studied ventilators .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: However , CMPS-SF and VAS were not significantly different between groups .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Additionally , the study demonstrates that NO in exhaled human breath can be measured rapidly , with high sensitivity , and in real time via the KNB , representing an affordable means to achieve this determination .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: After 2 months treatment , the TCM syndrome score in TCM-treated group was better , and the score of SAQ was higher than that in the control group ( all P < 0.01 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Continued follow-up monitoring of these children is necessary to assess neurobehavioral function , school performance , and possible susceptibility to disease .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: However , the between group differences were not statistically significant .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: A structured group reading programme induced a significant symptomatological cognitive and psychosocial amelioration in hospitalized patients with psychosis .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Three groups of 16 healthy subjects 55-70 y of age participated in a randomized , doubled-blinded , placebo-controlled intervention .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Evening-EA can significantly lower insomnia patients ' PSQI score , raise sleep rate , and reduce the hypnotic-taking frequency .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: To determine whether the administration of D-chiro-inositol , a putative insulin-sensitizing drug , would affect the concentration of circulating insulin , the levels of serum androgens , and the frequency of ovulation in lean women with the polycystic ovary syndrome .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: Patients in the ICU on study day 21 received a fourth dose .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: The overall incidence of OCR was higher with general anesthesia ( 63.3 % ) than with local anesthesia ( 14.4 % ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: GC was aspirated using an orogastric catheter and its volume and pH were measured .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: To assess the effect of patient completed agenda forms for the consultation and doctors ' education on identifying patients ' agendas on the outcome of consultations .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: One patient failed to decompress after successful stent deployment .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: In 3 Canadian centres , 100 patients undergoing Hematopoietic Stem Cell Transplantation will be randomized to either a restrictive ( target hemoglobin of 70-90 g/L ) or liberal ( target hemoglobin of 90-110 g/L ) red cell transfusion strategy , based daily hemoglobin values up to 100 days post-transplant .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: From July 2010 to June 2013 , 38 patients with degenerative scoliosis were randomly divided into spinal leveraging manipulation group and medicine group by coin tossing .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: In patients with recurrent duodenal ulcer , eradication of H. pylori by a regimen that does not have any direct action on the mucosa is followed by a marked reduction in the rate of recurrence , suggesting a causal role for H. pylori in recurrent duodenal ulcer .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Only compliance with almond intake advice related to blood pressure reduction ( systolic : r = -0.34 , n = 50 , P = 0.017 ; diastolic : r = -0.29 , n = 50 , P = 0.041 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The total effective rate was 78.6 % in the treatment group and 31.8 % in the control group , with significant difference between the two groups ( P < 0.05 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: To determine whether length of pre-operative treatment with gonadotrophin-releasing hormone agonists ( GnRHa ) may have different effects on uterine shrinkage and intra-operative blood loss , 36 patients with symptomatic uterine fibroids awaiting myomectomy were randomly divided into two groups .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: Both DAs lead to increased knowledge in healthy populations making hypothetical decisions , and use of the VCE did not improve knowledge or DC .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Statistically significant baseline-post-treatment changes were observed on the role , cognitive and social functioning scales as well as on the nausea and vomiting , pain and diarrhea symptoms .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Health centres in the South Sulawesi Province , Republic of Indonesia .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: This study was undertaken to evaluate ( 1 ) the feasibility and consumer satisfaction with a geriatrician-led supported discharge service for older adults living in residential care facilities ( RCF ) and ( 2 ) its impact on the uptake of Advanced Care Planning ( ACP ) and acute health care service utilisation .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Examinations were performed before and 1 , 30 , 180 days , one and two years after surgery .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: A total of consecutive 82 proteinuric patients treated with antihypertensive agents , including losartan , were randomized 10 mg of pravastatin or placebo with a 6-month treatment .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: There were significant dose-response relationships with CR oxybutynin for both UI episodes and dry mouth .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: ClinicalTrials.gov ; No. : NCT00685893 ; URL : www.clinicaltrials.gov .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: The serum concentrations of PICP ( 202.6 + / -11.5 vs 116.3 + / -5.4 microg/l ; mean + / - s.e.m. ) and ICTP ( 10.5 + / -0.6 vs 4.4 + / -0.3 microg/l ) doubled ( P < 0.001 ) during the first 6 months of GH treatment but returned to baseline by the end of the study ( 130.0 + / -10.4 and 5.6 + / -0.7 microg/l respectively ) , despite constantly elevated serum IGF-I levels ( 39.6 + / -4.1 nmol/l at 42 months vs 11.9 + / -0.9 nmol/l at baseline ; P < 0.001 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Mean percent reductions for the groups receiving 2 % dorzolamide twice daily and placebo twice daily were 13.1 % and 6.5 % , respectively .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Children allocated to RCC alone received more polypharmaceutical treatment .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: OS was not improved on the PG arm ( 6.2 months ) compared with the G arm ( 6.3 months ) ( P = 0.8477 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Patients who underwent cesarean delivery also received clindamycin ( 900 mg IV every 8 hours , for a total of three doses ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: The primary efficacy endpoint was sustained virologic response ( SVR ) , defined as undetectable HCV RNA ( < 50 IU/mL ) 24 weeks after the end of treatment .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: To evaluate the effects of Silymarin and/or vitamin E on OS markers and hemoglobin levels in patients on hemodialysis .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: Mean pain scores ranged from 1.3 to 4.9 .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The relatively simple electronic intervention evaluated can significantly improve the follow-up of FOBT + results .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: To compare lovastatin with placebo for prevention of the first acute major coronary event in men and women without clinically evident atherosclerotic cardiovascular disease with average total cholesterol ( TC ) and LDL-C levels and below-average high-density lipoprotein cholesterol ( HDL-C ) levels .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: The most frequently reported cardiovascular adverse events during double-blind treatment ( placebo vs frovatriptan twice daily ) were chest discomfort ( 2 % and 3 % ) , chest pain ( 2 % and 2 % ) , and hypertension ( 0 and 2 % ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Six had spinal cord injury with lesions ranging from C2 to C5-6 .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: We hypothesized that if PAS21 .5 and PAS25 increased corticospinal excitability by two entirely separate mechanisms then their effects might summate if we intermixed them in the same session .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: These differences were significant for ultrasound ( p < 0.001 ) and palpation ( p < 0.05 ) in large-for-gestational-age fetuses .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: One group ( group A ) received photopheresis for 1 year , the other group ( group B ) received no treatment at all .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Secondary outcomes included pregnancy as well as changes in fasting glucose and insulin .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: RSII with rocuronium followed by reversal with sugammadex allowed earlier re-establishment of spontaneous ventilation than with succinylcholine .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: This experimental study measured the biomechanics of SMT applied to C2 .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: However , the CORE group showed a sustained improvement in pain and functional status with two-fold differences at the end of the 6 months of follow-up .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Ibandronate , a potent , nitrogen-containing bisphosphonate developed for intermittent administration in postmenopausal osteoporosis , aims to overcome current adherence issues with daily and weekly oral bisphosphonates through once-monthly oral dosing .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Of the secondary outcomes , subcutaneous closure of the fat layer was associated with a longer admission time ( median 4 days ; IQR 3-5 versus 3 days ; IQR 3-5 , p-value 0.023 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Twice-daily dosing of calcipotriene was compared with its vehicle , for up to 8 weeks , in a double-blind study of 277 patients at 10 study centers in the United States .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: First patient controlled analgesia ( PCA ) request , cumulative morphine consumption and pain intensities within the first 72 h were compared .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Evidence on the real effectiveness of statins on acute coronary syndrome ( ACS ) incidence is scarce .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Variables associated with VF loss and VF variability may help identify patients who need greater clinical scrutiny .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Randomised controlled trial .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: The control group was not given this advice .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: The current study was conducted to investigate the dependence between progression-free survival ( PFS ) and overall survival ( OS ) in patients with metastatic renal cell carcinoma ( mRCC ) and to explore whether PFS can be used as an intermediate endpoint of OS in this patient population .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Participants with large-bowel adenomatous polyps diagnosed in the past 6 mo were randomly assigned to either the intervention ( n = 1037 ) or the control ( n = 1042 ) group and remained in the trial for 4 y. Three dietary assessment instruments were used to measure dietary change : food-frequency questionnaires ( in 100 % of the sample ) , 4-d food records ( in a 20 % random cohort ) , and 24-h dietary recalls ( in a 10 % random sample ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Multivitamins plus selenium in a single supplement , vs placebo , also reduced the risk of secondary events of combined outcomes for disease progression ( CD4 cell count 250/L , AIDS-defining conditions , or AIDS-related death , whichever occurred earlier [ adjusted HR , 0.56 ; 95 % CI , 0.33-0 .95 ; P = .03 ; AER , 6.48 / 100 person-years ; censoring rate , 0.90 ; 23 events ] ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Patients who have undergone the Fontan procedure have decreased cardiac output , increased systemic vascular resistance , abnormal diastolic function , and decreased exercise capacity compared with normal people .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Comfilcon A silicone hydrogel contact lenses were used during the trial .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Patients of group 1 ( n = 62 ) received of fixed combination of nebivolol and amlodipine , while those of group 2 ( n = 62 ) received free combination of nebivolol and amlodipine .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Both regimens were well tolerated with no serious adverse events .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}]