["[Dialogue between User and Assistant on 2024-01-01 00:00]\n<User>Here are categorized examples with their respective labels:\n\nSample: Students were randomly assigned to experimental conditions , and hypotheses were tested with a multiple-choice test and self-report scales .\n\nLabels: 2\n\nSample: Primary outcome measures were falls and resultant injuries occurring over the 12-month follow-up period .\n\nLabels: 2\n\nSample: 8-SQ group participants received 6 SQ injections with m30 and m42 `` annual '' boosters ; participants in the 8-IM group received intramuscular ( IM ) injections according to the same schedule .\n\nLabels: 2\n\nSample: To compare bleeding patterns after immediate vs. conventional oral contraceptive ( OC ) initiation .\n\nLabels: 3\n\nSample: The thiazolidinedione antidiabetic drug pioglitazone is metabolized mainly by cytochrome P450 ( CYP ) 2C8 and CYP3A4 in vitro .\n\nLabels: 3\n\nSample: Randomised , double-blind , controlled study .\n\nLabels: 2\n\nSample: 732 people were screened and 515 were randomly assigned to insulin glargine ( n = 250 ) or sitagliptin ( n = 265 ) .\n\nLabels: 4\n\nSample: In addition , the patients ' 12 daily activity scores were used to identify patients who were characterised by low levels of physical activity throughout the registration period .\n\nLabels: 2\n\nSample: women in the third trimester of pregnancy ( n = 890 ) were recruited by a research midwife while waiting for their antenatal clinic appointment .\n\nLabels: 2\n\nSample: A single dose of PCV7 induced significant increases in serotype-specific memory B-cell populations in peripheral blood indicating a T-dependent response .\n\nLabels: 4\n\nSample: Consecutive patients with acute lymphocytic leukemia in remission at the time of transplantation .\n\nLabels: 2\n\nSample: Methods for oral hygiene vary from country to country and from culture to culture .\n\nLabels: 0\n\nSample: Second , in a three-group , parallel , randomised , double-blind study , each group of four subjects received q.d. , over 8 days , 2.5 , 10 or 20 mg of MDL 100,240 orally .\n\nLabels: 2\n\nSample: A motor control laboratory in a university setting .\n\nLabels: 2\n\nSample: total knee arthroplasty is an effective means for relieving the symptoms associated with degenerative arthritis of the knee .\n\nLabels: 0\n\nSample: Fifty-seven patients completed baseline and 6-month assessments consisting of an interview , measures of body mass index , blood pressure , fasting blood chemistry , and accelerometry .\n\nLabels: 2\n\nSample: Analyses applied intention-to-treat longitudinal mixed models .\n\nLabels: 2\n\nSample: This study was initiated to evaluate the effect of a pain control infusion catheter in managing postoperative pain .\n\nLabels: 3\n\nSample: Though this study was not powered to directly compare the efficacy of the 2 drugs , topiramate showed superiority over frovatriptan at Month 2 in reduction of headache days , which was a secondary end point in the study ( P = .036 ) .\n\nLabels: 4\n\nSample: The primary efficacy variable was the change from baseline in total AM plus PM diary nasal symptom score over the first 15 days of treatment .\n\nLabels: 2\n\nSample: Baseline demographics did not differ with the exception of cord pH. For each subject , the percentage of temperatures in the target range was calculated .\n\nLabels: 4\n\nSample: Significant pain relief and improvement in disability were defined as 50 % or more .\n\nLabels: 2\n\nSample: Vaccinees were enrolled in a nasopharyngeal carriage study from February 2001 to January 2002 to assess the duration of protection against pneumococcal carriage induced by PnCRM7 .\n\nLabels: 2\n\nSample: Analysis of the 66 enroled patients having completed postoperative assessment was performed .\n\nLabels: 2\n\nSample: It also examined which clinical variables were independently correlated with tubular damage .\n\nLabels: 2\n\nSample: Povidone-iodine soaks are not helpful in the postoperative management of hand infections\n\nLabels: 1\n\nSample: Four hundred forty-nine patients with untreated Graves ' disease ( GD ) were randomly assigned to three groups according to ATD type and/or dosage : 15 mg/day MMI , 30 mg/day MMI and 300 mg/day PTU .\n\nLabels: 2\n\nSample: This improved with age and decreased after treatment .\n\nLabels: 4\n\nSample: The results of the induction therapy and survival in patients with different variants of the transcripts were also similar .\n\nLabels: 4\n\nSample: Children who had their tonsils removed by coblation were found to return to their normal diet far sooner than those who underwent bipolar dissection .\n\nLabels: 4\n\nSample: By 12 weeks , CD had further increased to 199 ( 118-550 ) m and MWD had more than doubled to 538 ( 250-1750 ) m ( P < 0.001 and P = 0.001 ) .\n\nLabels: 4\n\nSample: More steps were accumulated in the group-led versus the independent phase .\n\nLabels: 4\n\nSample: Quadriceps forces were similar between the groups at 18-month follow-up .\n\nLabels: 4\n<Assistant>Noted. I'll remember these details.", "[Dialogue between User and Assistant on 2024-01-02 00:00]\n<User>The following are classification examples with their corresponding labels:\n\nSample: Clinically significant adverse effects did not occur despite variable antipsychotic serum levels with or without sertraline .\n\nLabels: 1\n\nSample: A modified 4-point flexural testing technique was used to measure strength , and porcelain buttons were bonded to the beam between the 2 central loading points .\n\nLabels: 2\n\nSample: Twenty-six patients who had undergone resection of colorectal metastases were treated with intranodal injections of an autologous tumor lysate - and control protein [ keyhole limpet hemocyanin ( KLH ) ] - pulsed DC vaccine .\n\nLabels: 2\n\nSample: A secondary aim was to use the `` expert '' panel , in an attempt to distinguish between tooth cleaning efficacy of 4 head/model combinations of the oscillating rotating electric brush .\n\nLabels: 3\n\nSample: A subgroup of patients with stage Ta cancer in whom at least 1 tumor was resected 12 month before treatment showed the most benefit from long-term prophylactic treatment in terms of disease-free survival .\n\nLabels: 4\n\nSample: Subjects were 246 patients enrolled in the placebo arm of a randomized , controlled trial of tobramycin for inhalation .\n\nLabels: 2\n\nSample: However , no tests have compared these essential oils , i.e. Listerine ( ) , against their true vehicle controls .\n\nLabels: 0\n\nSample: Patients in group B were given operation alone .\n\nLabels: 2\n\nSample: Initially , epidural analgesia was more effective ( P = 0.01 ) , and three patients in the fentanyl group were given epidural due to unsatisfactory pain relief .\n\nLabels: 4\n\nSample: A randomized , double-blind , three-group experimental study : experimental ( therapeutic touch ) , placebo ( placebo therapeutic touch ) , and control ( usual care ) .\n\nLabels: 2\n\nSample: The control subjects were not offered any prophylactic therapy , but were free to receive treatment or exercises .\n\nLabels: 2\n\nSample: Observational data suggest that the use of statins may improve outcomes for such conditions as sepsis and pneumonia .\n\nLabels: 0\n\nSample: The identification of ring enhancement on T1-weighted images attests to the significant blood-pool effects of USPIO particles .\n\nLabels: 1\n\nSample: Australia , New Zealand and United Kingdom participants were randomised to receive a DA ( DA group ) or standard trial consent materials ( control group ) .\n\nLabels: 2\n\nSample: Use of repeated dialogic reading and hands-on activities facilitates vocabulary acquisition .\n\nLabels: 1\n\nSample: An advance directive redesigned to meet most adults ' literacy needs may better enable patients to engage in advance care planning .\n\nLabels: 1\n\nSample: To evaluate the effect on clinical outcome and antibiotic use of two strategies to diagnose ventilator-associated pneumonia and select initial treatment for this condition .\n\nLabels: 3\n\nSample: The study enrolled 73 patients ( WL , n = 38 ; RSL , n = 35 ) .\n\nLabels: 4\n\nSample: Chemotherapy followed by involved field radiotherapy , as compared with chemotherapy alone , is associated with better event-free survival , but no survival benefit is observed for patients for limited-stage aggressive non-Hodgkin 's lymphoma .\n\nLabels: 1\n\nSample: DESIGNS After a placebo run-in period , 27 patients with essential hypertension World Health Organization stages I and II were assigned randomly to 6-month double-blind treatment with either a diuretic ( hydrochlorothiazide plus triamterene ) or a converting enzyme inhibitor ( trandolapril ) , to which the calcium antagonist amlodipine could be added after 3 months if required for better blood pressure control .\n\nLabels: 3\n\nSample: One hundred seventy community-dwelling adults , aged 75 and older , with subthreshold depression .\n\nLabels: 2\n\nSample: The experimental group undertook up to 30 minutes of treadmill walking with body weight support via an overhead harness per day while the control group undertook up to 30 minutes of overground walking .\n\nLabels: 2\n\nSample: To investigate the effect of intravenous ( IV ) landiolol , a novel ( 1 ) - adrenergic blocker , on the minimum alveolar concentration ( MAC ) of sevoflurane in adult women .\n\nLabels: 3\n\nSample: However , physicians have been reluctant to use RVOT pacing because of concerns that defibrillation efficacy might be adversely affected .\n\nLabels: 0\n\nSample: There was no statistically significant reduction in the rate of ICU-acquired infections : 33.2 % in the standard insulin therapy group compared with 27.17 % in the intensive insulin therapy group ( RR : 0.82 ; 95 % CI : 0.63 to 1.07 ) .\n\nLabels: 4\n\nSample: Diaphragm dysfunction is a complication of cardiac surgery with partial or absent spontaneous recovery in most cases .\n\nLabels: 3\n\nSample: We conducted a randomized controlled crossover study to compare the efficacy of diuretics between furosemide alone and the combination of furosemide plus albumin in stable hypoalbuminemic CKD patients by measuring urine output and sodium .\n\nLabels: 2\n\nSample: Subjects were willing to spend on average $ 15.89 / wk ( range $ 1 to $ 75 ) to alleviate the problems of seasonal ragweed rhinitis .\n\nLabels: 4\n\nSample: Patients were randomized following surgical resection to receive treatment with either postoperative irradiation alone , or postoperative irradiation plus three cycles of cisplatin and 5-fluorouracil .\n\nLabels: 2\n\nSample: Porcine-derived surfactant , 50 mg/kg body weight , was instilled into the trachea .\n\nLabels: 2\n\nSample: After accounting for these risk factors , concurrent bevacizumab doubles the odds of a GI AE , but is not appreciably increased by continuation beyond chemotherapy .\n\nLabels: 1\n\nSample: Electrocardiograms were recorded and stored to evaluate changes in HRV .\n\nLabels: 2\n\nSample: On the basis of estimates adjusted for changes in the general population , each year was associated with a 6 % increase in the likelihood of receiving an opioid prescription from 2000 to 2010 .\n\nLabels: 4\n\nSample: Combination treatment did not lead to superior functioning and did not facilitate methylphenidate discontinuation .\n\nLabels: 4\n\nSample: The therapeutic course for both was six months .\n\nLabels: 2\n\nSample: Fifty ambulatory volunteers were recruited within 24 h of developing symptoms of the common cold for a randomized , double-blind , placebo-controlled trial of zinc .\n\nLabels: 2\n\nSample: These data suggest that stiffening of large elastic artery is reflected more by ambulatory than office BP elevations , systolic BP being much more important than diastolic .\n\nLabels: 1\n\nSample: The combination treatment seems to afford better BP control and appears to be a favourable therapeutic option in patients with renal disease and hypertension .\n\nLabels: 1\n\nSample: Best spectacle-corrected visual acuity decreased by logMAR 0.003 ( P = .883 ) over 3 months , 0.056 ( P = .092 ) over 6 months , and 0.12 ( P = .036 ) over 12 months .\n\nLabels: 4\n\nSample: Safety and reactogenicity profiles were comparable across groups .\n\nLabels: 4\n\nSample: We used a matched cohort design , aiming to follow up the 13 patients with confirmed awareness .\n\nLabels: 2\n<Assistant>I understand. I'll keep this in mind.", "[Dialogue between User and Assistant on 2024-01-03 00:00]\n<User>I have some labeled classification examples for you to study:\n\nSample: The predefined primary outcome measure was patient reported adequate symptom relief .\n\nLabels: 2\n\nSample: The signal intensities of injured myocardium , remote myocardium , left ventricular cavity , and air were measured in identical locations using anatomical landmarks and dedicated software .\n\nLabels: 2\n\nSample: We conclude that injections were as effective as splinting in LE .\n\nLabels: 1\n\nSample: Intermittent catheterization is the recommended standard treatment for neurogenic bladder dysfunction .\n\nLabels: 3\n\nSample: By intention to treat analysis , target lesion revascularization was required in 4 lesions , all of which were randomized to the predilatation group ( p = 0.04 ) .\n\nLabels: 4\n\nSample: Significant differences in response to induced ketosis were found among non-carriers of putative gain-of-function polymorphisms in rs1143627 and rs16944 in the IL1B gene and among variants of the polymorphism rs2251101 in the IDE gene .\n\nLabels: 4\n\nSample: The primary end point occurred in 2.4 % of patients treated with atorvastatin reload and in 8 % in the placebo arm ( p = 0.0088 ) .\n\nLabels: 4\n\nSample: Ninety-two percent of patients ( 36 of 39 ) in group B had an HBV DNA response ( median change of -4.6 log ( 10 ) copies/mL ) and improved liver chemistries ( P < or = 0.001 ) .\n\nLabels: 4\n\nSample: Microbiologic tests were performed on each endoscope afterwards .\n\nLabels: 2\n\nSample: Comparing the analysed possible risk factors age , euroSCORE and sRAGE changes , no difference was observed regarding 30-day mortality .\n\nLabels: 4\n\nSample: We compared basic material characteristics and MTS hip joint simulator wear rates of a crosslinked polyethylene ( Duration ) to those of conventional polyethylene .\n\nLabels: 2\n\nSample: For the secondary outcome measures `` poor outcome '' ( Rankin > 3 ) and `` excellent outcome '' ( Rankin 0 ) , we used the `` intention-to-treat '' principle .\n\nLabels: 2\n\nSample: 236 patients were recruited , 118 received standard therapy alone and 118 additional NIV .\n\nLabels: 4\n\nSample: For QLQ-CR38 , the mean scores for `` body image '' and `` future perspective '' were high at 79.6 and 69.7 respectively .\n\nLabels: 4\n\nSample: The primary outcome was change in executive functioning .\n\nLabels: 2\n\nSample: Chlorambucil plus ofatumumab is therefore an important treatment option for these patients who can not tolerate more intensive therapy .\n\nLabels: 1\n\nSample: It was observed that phoneme discrimination training benefits some but not all people with mild hearing loss .\n\nLabels: 1\n\nSample: To explore the action of pingxiao capsules ( PXC ) and its significance in the treatment of late stage mammary cancer ( LSMC ) .\n\nLabels: 3\n\nSample: Dyssynchrony was determined as the standard deviation of time to peak transverse strain between 12 segments of apical four - and two-chamber views , and contractile function as global longitudinal strain ( GLS ) by averaging longitudinal strain over these 12 segments .\n\nLabels: 4\n\nSample: Alternatively , cereal fiber in the diet may be a marker for another component of whole grains that imparts health advantages or a healthy lifestyle .\n\nLabels: 1\n\nSample: The participants with Type 1 diabetes had a total of 336 hypoglycaemic events with a rate of 42.89 events per patient per year .\n\nLabels: 4\n\nSample: To evaluate the addition of ezetimibe or placebo to on-going simvastatin treatment on attaining the LDL-C treatment target of < / = 2.60 mmol/L ( 100 mg/dL ) in coronary heart disease ( CHD ) patients with hypercholesterolemia .\n\nLabels: 3\n\nSample: Three factors contributed to poorer reliabilities for process measures : ( 1 ) an inability of reviewers to differentiate among cases with respect to the quality of management , ( 2 ) systematic bias from individual reviewers , and ( 3 ) systematic bias related to the professional training of the reviewer ( ie , physician or nurse practitioner ) .\n\nLabels: 4\n\nSample: Clinical scales resulted significantly related .\n\nLabels: 4\n\nSample: Of the 611 patients , 422 were alive after 10.32 1.43 years .\n\nLabels: 4\n\nSample: Noncompliance with referral to a physician for retesting and diagnosis is a concern in public cholesterol screening .\n\nLabels: 0\n\nSample: Results from this study will help to determine the efficacy of supervised twice-weekly pulmonary rehabilitation upon exercise capacity and quality of life in patients with bronchiectasis and will contribute to clinical practice guidelines for physiotherapists in the management of this population .\n\nLabels: 1\n\nSample: However , the preliminary analysis over 3 years indicates that the average cost of the procedure remains lower than the total cost of TURP for the same period .\n\nLabels: 1\n\nSample: Incidence of cough with losartan ( 29 % ) lower than that for lisinopril ( 72 % ; P < 0.01 ) and similar to that for hydrochlorothiazide ( 34 % ) .\n\nLabels: 4\n\nSample: Baseline CCT measurements obtained by the USP were significantly ( P < 0.0001 ) higher than that of SP-3000P by about 28m and 29m in sessions 1 and 2 , respectively .\n\nLabels: 4\n\nSample: This was a double blind placebo controlled , randomized , crossover study .\n\nLabels: 2\n\nSample: Primary outcomes are depressive symptoms and diabetes-specific emotional distress .\n\nLabels: 2\n\nSample: The results indicate that child maltreatment , psychopathy and HPA-axis reactivity interact to provide a confluence over aggressive behavior , and intervention efforts need to consider all these factors .\n\nLabels: 1\n\nSample: The 28-day low-GL diet led to 4 % lower fasting concentrations of IGF-1 ( 10.6 ng/ml , P = 0.04 ) and a 4 % lower ratio of IGF-1 / IGFBP-3 ( 0.24 , P = 0.01 ) compared with the high-GL diet .\n\nLabels: 4\n\nSample: Sixty cervical cancer post-operation patients with catheter due to uroschesis were randomly and equally divided into late treatment group ( acupuncture intervention was given from the over 15th day on after surgery ) and early treatment group ( acupuncture was given from the 7th day to the 14th day after surgery ) .\n\nLabels: 2\n<Assistant>I've processed this information and will remember it.", "[Dialogue between User and Assistant on 2024-01-04 00:00]\n<User>I want you to learn from these classified examples:\n\nSample: Variances of 24-h data ( pH above 3 and 4 , median pH , [ H + ] concentrations ) were significantly lower with rabeprazole than with omeprazole ( p < 0.0001 ) .\n\nLabels: 4\n\nSample: The only significant independent variable for the area of disclosed plaque was the subject ( p < 0.001 ) .\n\nLabels: 4\n\nSample: Of the 48 enrolled patients , 11 cases were excluded for failing to complete the initial work-up .\n\nLabels: 4\n\nSample: The same doctor obtained the saphenous vein of each patient by a uniform method .\n\nLabels: 2\n\nSample: PATIENTS , NURSES AND INTERVENTIONS : During a 6week period 145 consecutive adult patients admitted to the ICU after uncomplicated cardiothoracic surgery were randomized into two groups : for one group the documentation was carried out using a paper-based registration ( Paper ) , in the second group an ICIS was used for documentation .\n\nLabels: 2\n\nSample: The studies demonstrate patients on dialysis can be safely and effectively converted from IV paricalcitol or doxercalciferol to oral doxercalciferol .\n\nLabels: 1\n\nSample: This study demonstrates that combined antiplatelet therapy after stent placement in patients with acute myocardial infarction is associated with an overall better clinical and angiographic outcome than anticoagulant therapy .\n\nLabels: 1\n\nSample: Immediately after insulin administration , participants drank 500 mL of Ensure ( ) ( Abbott Australasia Pty. Ltd. , Botany , NSW , Australia ) ( providing 2,240 kJ of energy , 18.6 g of protein , 96 g of carbohydrate , and 3 g of fat ) .\n\nLabels: 2\n\nSample: The number of placebo and light sessions was matched with respect to season .\n\nLabels: 2\n\nSample: The increase of TAT-III and prothrombin fragments F1 + 2 in patients with caesarean sections was evidently lower than in normal deliveries and was not influenced significantly by aprotinin .\n\nLabels: 4\n\nSample: We evaluated the efficacy and feasibility of combining bevacizumab with trastuzumab and docetaxel in patients with HER2 - positive MBC who received 0-1 prior chemotherapy regimens for metastatic disease .\n\nLabels: 3\n\nSample: Patients assessed the level of pain with visual analog scales .\n\nLabels: 2\n\nSample: Causes of death were obtained from death certificates .\n\nLabels: 2\n\nSample: All had sputum retention , with an elevated C-reactive protein of 113 mg/L ( range 13-231 mg/L ) and a white-cell count of 14x10 ( 9 ) cells/L ( range 7-25x10 ( 9 ) cells/L ) .\n\nLabels: 2\n\nSample: We examined ezetimibe use trends in the US and Canada before and after the reporting of the ENHANCE trial .\n\nLabels: 0\n\nSample: Eyes were followed for a mean of 9.5 months after their last surgical procedure ( range , 2 weeks-21 months ) .\n\nLabels: 4\n\nSample: HSD had a longer duration of effect than mannitol ( p = .044 ) .\n\nLabels: 4\n\nSample: In addition , FC improved on DTT and oxygen saturation , increased , both at rest and peak exercise .\n\nLabels: 4\n\nSample: After administration of ionic CMs , the frequency of late allergy-like reactions was in the same range ( 0.42 % ) as for non-ionic CMs , but the frequency of immediate allergy-like reactions was much higher ( 6.99 % vs 0.52 % ) .\n\nLabels: 1\n\nSample: The letrozole/antagonist protocol is a cost-effective and patient-friendly protocol that may be used in poor ovarian responders for IVF/ICSI .\n\nLabels: 1\n\nSample: Hemodilution occurring with cardiopulmonary bypass imposes a risk for blood transfusion .\n\nLabels: 0\n\nSample: The purpose of this clinical study was to determine the effect of 1 - or 2-visit root canal treatment on the postoperative pain in the retreatment cases .\n\nLabels: 3\n\nSample: The objective of this study was to develop and qualify a physiologically based pharmacokinetic ( PBPK ) model for rivaroxaban doses of 10 and 20 mg in adults and to scale this model to the paediatric population ( 0-18 years ) to inform the dosing regimen for a clinical study of rivaroxaban in paediatric patients .\n\nLabels: 3\n\nSample: Reduction in thigh circumference of the treated areas exceeded those of the control areas for the upper , middle , and lower thigh in most subjects .\n\nLabels: 4\n\nSample: The outcome measures included operating time , complications , postoperative pain , return to normal activity , operating theater costs , and recurrences .\n\nLabels: 2\n\nSample: Among a subset of Latino patients , 95 % earned less than 25,000 US dollars and 73 % had an education of 6th grade or less .\n\nLabels: 4\n\nSample: We used two PP with antigonadotropic potencies , chlormadinone acetate ( CMA , 10 mg/day ) and cyproterone acetate ( CPA , 50 mg/day ) , administered orally for contraception in 187 SLE patients observed for 4634.6 months ( meanS.E . )\n\nLabels: 2\n\nSample: Eighteen patients had applanation tonometry , pulse wave analysis and echocardiography , before and after atenolol 75 mg , perindopril 4 mg and verapamil 240 mg , each given for 4 weeks , in a random order , with 2 weeks between medications .\n\nLabels: 4\n\nSample: This was a secondary analysis from a multicenter trial of 740 patients with suspected VAP randomized to bronchoscopy or endotracheal aspirate cultures ; all received empirical broad-spectrum antibiotics .\n\nLabels: 2\n\nSample: The overall postoperative pain was lower ( p = 0.026 ) when staples were used to anchor mesh .\n\nLabels: 4\n\nSample: Between October 1989 and July 1993 , a total of 1860 women at low medical risk in early pregnancy , who participated in a randomized controlled trial of in-hospital birth center care versus standard care , gave birth .\n\nLabels: 2\n\nSample: Oral controlled-release oxycodone was twice as potent as oral controlled-release morphine in this single-dose , relative potency assay .\n\nLabels: 1\n\nSample: Patients were excluded if they manifested wheezing , stridor , or angioedema or if they had taken antihistamines or glucocorticoids within 5 days of arrival at the ED .\n\nLabels: 2\n\nSample: 38 children undergoing open-heart surgery .\n\nLabels: 2\n\nSample: Thirty subjects were selected , originally diagnosed with moderate to severe generalized periodontitis , following a periodontal maintenance care programme ( PMC ) .\n\nLabels: 2\n\nSample: During the period , 38 infants , whose parents accepted participation , were enrolled in the study .\n\nLabels: 2\n\nSample: The AUC of PMEA was unaffected by food .\n\nLabels: 4\n\nSample: Different biological markers were measured to detect possible physiological changes .\n\nLabels: 2\n\nSample: To determine whether circulating levels of osteopontin ( OPN ) , osteoprotegerin ( OPG ) , total soluble receptor activator of nuclear factor-kappa B ligand ( total sRANKL ) , and high-sensitivity C-reactive protein ( hsCRP ) change in patients with rheumatoid arthritis ( RA ) during immunosuppressive therapy .\n\nLabels: 3\n\nSample: The mean duration of follow-up was 17.7 + / - 7.4 months .\n\nLabels: 2\n\nSample: Cation-containing drugs have the potential to affect the absorption of quinolones .\n\nLabels: 3\n\nSample: Of 248 neonates enrolled , 126 were randomly assigned to the nitric oxide group and 122 to the control group .\n\nLabels: 4\n\nSample: The month 12 clinical outcome for anecortave acetate was improved in patients for whom reflux was controlled and who were treated within the 6-month treatment window ( 57 % vs. 49 % ; 95 % CI , -4.3 % favoring PDT to +21.7 % favoring anecortave acetate ) .\n\nLabels: 4\n\nSample: Each intervention was directed at 1 of the aforementioned 2 antecedents over first and second grades in 19 urban schools .\n\nLabels: 2\n<Assistant>Sure I will remember them.", "[Dialogue between User and Assistant on 2024-01-05 00:00]\n<User>Here are some annotated classification examples:\n\nSample: Hemodynamic and blood gas measurements were performed at baseline , at 1 h after randomization , and at 24-h intervals for 2 days .\n\nLabels: 2\n\nSample: These data may not be applicable to other circumstances , but the blinding process for abstract review may impact substantially on program content for section meetings .\n\nLabels: 1\n\nSample: After 16 weeks , BREAD group obtained higher scores in question 3 ( referring to the sensation of satiety ) that were significant at time 3 ( 7 versus 5 ; p < 0.05 ) and time 4 ( 8 versus 4 ; p < 0.01 ) .\n\nLabels: 4\n\nSample: To compare the performance of the Airtraq , X-Lite , and direct laryngoscopes for tracheal intubation for elective thyroid surgery .\n\nLabels: 3\n\nSample: We aimed to determine the effect of ACE genotype on the response to moderate intensity circuit resistance training in chronic heart failure ( CHF ) patients .\n\nLabels: 0\n\nSample: Tryptophan hydroxylase 1 ( TPH1 ) , which encodes the rate-limiting enzyme tryptophan hydroxylase in the biosynthesis of serotonin , is a candidate gene in the development and treatment response of major depressive disorder ( MDD ) ; however , its actual role is uncertain .\n\nLabels: 0\n\nSample: After eight weeks , the eight recipients of cyclosporine had marked improvement in erythema ( P = 0.003 ) , erosion ( P = 0.02 ) , reticulation ( presence of white lacelike lesions ; P = 0.007 ) , and pain ( P = 0.002 ) , whereas the eight recipients of vehicle had no change or minimal improvement .\n\nLabels: 4\n\nSample: Parents completed an interview on past and current services .\n\nLabels: 2\n\nSample: Intervention teens who reported more successful communication had a 42 % lower Risky Driving Score ( 95 % CI = 0.37 , 0.94 ) than control parents with less successful communication .\n\nLabels: 4\n\nSample: Participants are randomly allocated to two intervention groups ( the child intervention group and the child intervention combined with a parent program ) and a wait-list control group .\n\nLabels: 2\n\nSample: To compare the acceptability , compliance , and effectiveness of two forms of cholestyramine resin in the treatment of hypercholesterolemia in children .\n\nLabels: 3\n\nSample: To investigate the influence of elevated glucose level on epicardial/microvascular flow and survival in patients with acute ST-segment elevation myocardial infarction ( STEMI ) treated with primary percutaneous coronary intervention ( PCI ) .\n\nLabels: 3\n\nSample: Response rates were 75 % ( 15/20 ) for botulinum toxin type A versus 15 % ( 3/20 ) for placebo on the HDSS ( p < .001 ) .\n\nLabels: 4\n\nSample: Anesthesia was induced with 1 mg.kg ( -1 ) propofol 2 min after the start of remifentanil infusion .\n\nLabels: 2\n\nSample: Following initial evaluation at 1 year , subjects were invited to participate in a 4 year safety study .\n\nLabels: 2\n\nSample: Differences between the regimens were assessed by multivariate analysis corrected for time and regimen sequence .\n\nLabels: 2\n\nSample: At 4 other snack times , the children were offered fruit ( apple , peach , pineapple , or all 3 types ) .\n\nLabels: 2\n\nSample: Adjusted in-hospital , 30-day and 2-year clinical outcomes indicated comparable cardiac death ( 2-year overlap vs non-overlap : 3.0 % vs 2.1 % , p = 0.36 ) , major adverse cardiac events ( 13.3 % vs 10.7 % , p = 0.19 ) , target-vessel MI ( 3.9 % vs 3.4 % , p = 0.40 ) , clinically driven target vessel revascularisation ( 7.7 % vs 6.5 % , p = 0.32 ) , and definite/probable stent thrombosis ( 1.4 % vs 0.9 % , p = 0.28 ) .\n\nLabels: 4\n\nSample: Fourth - and fifth-year students sitting for an optional multiple choice examination were randomized to receive one of four instruction options : number-correct marking ( the control group ) ; alert to unsafe ; mark deduction for unsafe ; or correction for guessing .\n\nLabels: 2\n\nSample: The pharmacokinetics was adequately described by a 2-compartment model .\n\nLabels: 4\n\nSample: Demographic information and perioperative and postoperative outcomes data were obtained and analyzed during a 2 - to 6-month follow-up .\n\nLabels: 2\n\nSample: A total of 9 % of simulated patients were correctly managed ( given correct drugs , plus condoms and partner notification cards ) , recommended drug treatment was given in only 41 % of visits , and appropriate counselling was given in 48 % of visits .\n\nLabels: 4\n\nSample: In the 26 women with an embryonic pole within the persistent sac , expulsion occurred in 5 ( 36 % ) of 14 with and 7 ( 54 % ) of 13 without gestational cardiac activity ( GCA ) ( p = .45 ) .\n\nLabels: 4\n\nSample: The median peak values of CK-MB in the adenosine and standard groups were 2 and 4 microg/L , respectively ( P = 0.033 ) .\n\nLabels: 4\n\nSample: The purpose of the present study was to compare continuous and intermittent paroxetine treatment in oriental PMDD women during 6 months follow up .\n\nLabels: 3\n\nSample: This study determined whether change in tolerance to rectal distension after psychological treatments was associated with : 1 ) change in abdominal pain ; 2 ) change in psychological symptoms ; 3 ) a reported history of sexual abuse .\n\nLabels: 3\n\nSample: The primary outcome measurements were improvement in middle-ear pressure and hearing thresholds at eight weeks .\n\nLabels: 2\n\nSample: Brimonidine lowered mean peak IOP significantly more than timolol at week 2 and month 3 ( P < .03 ) ; no significant difference was observed between the groups for this variable at other visits throughout the 1-year course of the study .\n\nLabels: 4\n\nSample: The mean age was 16 years ( SD = 1.31 ) .\n\nLabels: 2\n\nSample: The results with the high-dose schedule in this age group are comparable to those reported in similar patients who have undergone allogeneic bone marrow transplantation during a first remission .\n\nLabels: 1\n\nSample: At age 20 years , participants underwent a comprehensive ophthalmic examination including measurement of ocular biometry and visual acuity .\n\nLabels: 2\n\nSample: These findings suggest that individualized nutrition interventions can be delivered by experienced dietitians with a reasonable investment of resources .\n\nLabels: 1\n\nSample: The primary endpoint was progression-free survival in the intention-to-treat population .\n\nLabels: 2\n\nSample: A randomized controlled trial method was used with 118 mothers .\n\nLabels: 2\n\nSample: Specific inhibitory effects are more pronounced when gas is infused into the jejunum , which underlines the importance of the small intestine in postprandial gas retention .\n\nLabels: 1\n<Assistant>Thank you for sharing. I've noted this information.", "[Dialogue between User and Assistant on 2024-01-06 00:00]\n<User>These are labeled examples for classification tasks:\n\nSample: Shorter and more efficient tidal peritoneal dialysis ( TPD ) was compared with continuous equilibrating peritoneal dialysis ( CEPD ) therapy in ARF by using their adequacies as accepted standards and analyzing the solute reduction indices ( SRI ) .\n\nLabels: 0\n\nSample: Systemic AEs were not statistically different when M-M-R II was administered alone ( 8.6 % ) or concomitantly with VARIVAX ( 8.9 % ) .\n\nLabels: 4\n\nSample: Assessment of safety and clinical efficacy over a 1-month period included timed tests of gait and bradykinesia , Unified Parkinson 's Disease Rating Scale ( UPDRS ) , and additional clinical , neurophysiological , and neuropsychological parameters .\n\nLabels: 2\n\nSample: The fingertip was preferred by 54.8 % , the forearm by 25 % , and the palm by 20.2 % of the children .\n\nLabels: 4\n\nSample: Therefore , the relationship between contraceptive use and trace elements needs to be investigated .\n\nLabels: 0\n\nSample: One eye of each patient received a CeeOn Edge IOL and the fellow eye , an AcrySof or PhacoFlex IOL .\n\nLabels: 2\n\nSample: Antibiotic therapy may provide a window of opportunity for maternal treatment with corticosteroids to decrease the risk for neonatal morbidity among these preterm gestations .\n\nLabels: 1\n\nSample: Microperimetry revealed reduced sensitivity over the treated area in 7 bolus PDT vs 1 in standard treated eyes ( p = 0.008 ) .\n\nLabels: 4\n\nSample: Fine-needle-aspiration biopsies were performed twice during the estrogen phases and twice during the estrogen plus progestogen phases of treatment .\n\nLabels: 2\n\nSample: Noradrenaline levels were reduced in patients with PHDC - .\n\nLabels: 4\n\nSample: To study the clinical effects of the Chinese drug Yimusake , used alone or in combination with trazodone hydrochloride , on primary premature ejaculation ( PE ) .\n\nLabels: 3\n\nSample: Blood samples obtained before and after treatment were subjected to routine hematologic and serum biochemical analyses .\n\nLabels: 2\n\nSample: Patients randomly allocated to the control group ( CG ) received standard pharmacologic therapy .\n\nLabels: 2\n\nSample: Storage symptoms had disappeared in 1 patient and de novo storage symptoms had developed in 2 since the previous followup .\n\nLabels: 4\n\nSample: Economic benefit of algorithm-based interventions at infliximab failure is maintained throughout 1 year .\n\nLabels: 1\n\nSample: However , intervention was associated with an increase in the percentage of body fat in boys ( 0.97 % ; 95 % CI , 0.14-1 .81 ; P = .02 ) .\n\nLabels: 4\n\nSample: At baseline , there were no differences in demographic or delivery characteristics between the groups .\n\nLabels: 4\n\nSample: The outcome of laparoscopic single-site and three-port ovarian cystectomy were evaluated .\n\nLabels: 2\n\nSample: To evaluate the accuracy of refractive prediction of 4 intraocular lens ( IOL ) power calculation formulas in eyes with axial length ( AL ) greater than 25.0 mm and to propose a method of optimizing AL to improve the accuracy .\n\nLabels: 3\n\nSample: Interventions targeted for diabetes prevention and diabetes management are critical for persons with serious mental illness , particularly among those who also abuse substances .\n\nLabels: 1\n\nSample: A steady state was reached during the last 3 months .\n\nLabels: 4\n\nSample: We evaluated the anesthetic effects of lidocaine with epinephrine and/or bicarbonate injected into the epidural space by bolus or catheter injection .\n\nLabels: 3\n\nSample: The study enrolled 51 patients ( 76 eyes ) .\n\nLabels: 4\n\nSample: The 90 % confidence intervals for the `` test/reference '' mean ratios of the ln-transformed pharmacokinetic variables C ( max ) , AUC ( 0-t ) and AUC ( 0 - ) were clearly within the conventional bioequivalence range of 80-125 % .\n\nLabels: 4\n\nSample: A pharmacokinetic model was fitted to the paracetamol data .\n\nLabels: 2\n\nSample: 1/2-PN + GH ( n = 8 ) maintained TBN and fat but lost MM ( P = 0.038 ) .\n\nLabels: 4\n\nSample: This paper reports on a stepdown maintenance contingency and 1-year follow-up in 110 patients who were maintained on methadone ( 50 or 70 mg/day ) and who had completed a contingency management trial targeted to decreasing their opiate use .\n\nLabels: 0\n\nSample: Community ( n = 4 ) and Veterans Affairs ( VA ) NHs ( n = 4 ) .\n\nLabels: 2\n\nSample: Secondary outcomes included changes in sexual activity , sexual distress , Derogatis Interview for Sexual Functioning , lean body mass , fat mass , muscle strength and power , and physical function .\n\nLabels: 2\n\nSample: Both treatments improved homeostasis model assessment - ( HOMA - ) and homeostasis model assessment-insulin resistance ( HOMA-IR ) significantly .\n\nLabels: 4\n\nSample: We sought to identify relationship and partner-related moderating variables that influence the effectiveness of both a couples and a solo learning intervention designed to increase skin self-examination behavior in a sample of patients at risk for developing melanoma .\n\nLabels: 3\n\nSample: The benefit was most marked in patients with a baseline calculated GFR < or = 45 ml/min .\n\nLabels: 1\n\nSample: Primary outcome measures were visual analog scale pain scores for back pain , limb pain , and general pain .\n\nLabels: 2\n\nSample: These are potentially of genetic origin , since research in healthy subjects suggests that vulnerability for pathological gambling may be linked to variation in the dopamine receptor D4 ( DRD4 ) gene .\n\nLabels: 0\n\nSample: Results indicated that SA decreased significantly ( P < 0.05 ) 180 min following the 50 % 1RM condition .\n\nLabels: 4\n\nSample: The relationship between training volume and the impact on walking distance was explored by dividing training volume data into tertiles and relating them to the median change in maximum walking distance at 3 and 12 months .\n\nLabels: 2\n\nSample: Bivariate analysis revealed that the effectiveness of influenza vaccination was not modified by the severity of COPD , comorbid diseases , age , gender , or current smoking status .\n\nLabels: 4\n\nSample: Patients were randomly treated with cefotiam hexetil 200 mg bid over a 5 day period followed by 5 days of placebo , or with cefotiam hexetil 200 mg bid over a 10 day period .\n\nLabels: 2\n\nSample: Baseline mean barriers scores were lower than reported in previous Australian studies at 1.33 ( standard deviation : 0.92 ) .\n\nLabels: 4\n\nSample: Randomised controlled trial .\n\nLabels: 2\n\nSample: The persistent decrease in hematocrit suggests that plasma volume expansion plays a role in the attenuation of nitrate effects .\n\nLabels: 1\n\nSample: Patients showing a 10 % or greater improvement were compared between the two groups .\n\nLabels: 4\n<Assistant>Thanks for letting me know. I'll keep track of this.", "[Dialogue between User and Assistant on 2024-01-07 00:00]\n<User>The following are classification examples with their corresponding labels:\n\nSample: Hospital anxiety and depression scale , mental adjustment to cancer scale , Rotterdam symptom checklist , psychosocial adjustment to illness scale .\n\nLabels: 2\n\nSample: The link between acute physiological changes and improved outcomes associated with CLR remain to be determined .\n\nLabels: 1\n\nSample: Cystoid Macular Edema ( CME ) is one of the most common and sight threatening complications of uveitis .\n\nLabels: 0\n\nSample: Electron microscopic evaluation of barrier structure displayed prevalently ordered stratum corneum lipid layers and regular lamellar body extrusion in pimecrolimus-treated skin but inconsistent extracellular lipid bilayers and only partially filled lamellar bodies after betamethasone treatment .\n\nLabels: 4\n\nSample: To evaluate intercostal nerve block effectiveness with ropivacaine in patients undergoing emergency open cholecystectomy under general anesthesia compared with conventional management .\n\nLabels: 3\n\nSample: A good scientific research question with flexible study design and active involvement of the clinicians are important factors driving recruitment .\n\nLabels: 1\n\nSample: Patients in the aprotinin group received less blood per kilogram of body weight than patients in the placebo group ( 32 + / - 25 ml/kg compared with 52 + / - 34 m/kg , respectively ; p = 0.04 ) .\n\nLabels: 2\n\nSample: The aim of this study is to provide the scientific basis for disseminate the programme to the remaining primary health centres in Osakidetza , as a novel way of addressing prevention of DM2 .\n\nLabels: 1\n\nSample: The most frequent adverse events involved the central nervous system and occurred in comparable proportions in the 3 treatment groups .\n\nLabels: 4\n\nSample: The inter-patient variability in clearance was related to plasma creatinine and percent above ideal body weight .\n\nLabels: 4\n\nSample: An easily implemented school-based jumping intervention augments aBMD at the trochanteric region in the prepubertal and early pubertal skeleton .\n\nLabels: 1\n\nSample: Tooth sensitivity and oral irritation were the most common safety findings in the tray and dentifrice groups ( there were no adverse events in the paint-on group ) , and no subject discontinued treatment early because of a treatment-related adverse event .\n\nLabels: 4\n\nSample: Significant improvements were seen with ferric carboxymaltose in the distance on the 6-minute walk test and quality-of-life assessments .\n\nLabels: 4\n\nSample: Shear force was determined by averaging the stable shear force lasting for 10 measurement points .\n\nLabels: 2\n\nSample: Multisite randomized controlled double-blind trial with two treatment groups .\n\nLabels: 2\n\nSample: Current Controlled Trials ISRCTN94871417 .\n\nLabels: 0\n\nSample: The quality of life , morbidity of anxiety or depression of the intervention and the control group were comparable at the baseline ( P > 0.05 ) .\n\nLabels: 4\n\nSample: Prospective randomized trial ( Canadian Task Force classification I ) .\n\nLabels: 2\n\nSample: Both treatments resulted in significantly improved voice as rated by the patients .\n\nLabels: 1\n\nSample: The aim of this study was to determine the prevalence of asymptomatic recurrences of AF after an apparently successful catheter ablation procedure for AF .\n\nLabels: 0\n\nSample: The difference between groups was significant ( p < 0.05 ; 95 % CI , 10-146 .1 ) .\n\nLabels: 4\n\nSample: Parent , child , and clinician report measures of child anxiety were completed at 3 , 6 , and 12 months posttreatment .\n\nLabels: 2\n\nSample: This study found that a single drop of latanoprost significantly reduces intraocular pressure 8 h after dosing .\n\nLabels: 1\n\nSample: Significant predictors for the prescription of fluoroquinolones from both patient and GP data were identified .\n\nLabels: 4\n\nSample: The risk of severe decompression sickness ( DCS ) increases rapidly above 6248 m ( 20,500 ft ) and is greater when breathing higher proportions of inert gas .\n\nLabels: 0\n\nSample: Prepulse inhibition and working memory may both relate to PFC DA levels according to an inverted U-shaped curve function .\n\nLabels: 1\n\nSample: A total of 12 ( 75 % ) responders who received placebo and 19 ( 86 % ) who received bacillus Calmette-Guerin considered themselves to remain moderately or markedly improved at week 68 .\n\nLabels: 4\n\nSample: A dose-dependent reduction in troponin I levels was observed with Serp-1 at 8 , 16 , 24 , and 54 hours ( P < 0.05 ) and in creatine kinase-MB levels at 8 , 16 , and 24 hours after dose ( P < 0.05 ) .\n\nLabels: 4\n\nSample: Torcetrapib , a cholesteryl ester transfer protein ( CETP ) inhibitor , increases HDL cholesterol levels , but the functional effects associated with this mechanism remain uncertain .\n\nLabels: 0\n\nSample: Fifty patients were randomly assigned to receive routine antibiotic and anti-inflammatory treatment alone ( control patients ) or a combination of micronized purified flavonoid fraction with identical antibiotic and anti-inflammatory treatment ( micronized purified flavonoid fraction patients ) .\n\nLabels: 2\n\nSample: The 12-month intervention included 2 in-person orientation sessions followed by up to 30 telephone sessions .\n\nLabels: 2\n\nSample: For the dynamic-balance test , all groups decreased the ML COP movement on the dominant limb by a small amount ( ~ 5 mm ) ; however , the SFE group was able to decrease COP movement much more than the TCE group in the nondominant limb .\n\nLabels: 4\n\nSample: Colorectal cancer ( CRC ) screening rates are increasing , but they are still low , particularly in ethnic minority groups .\n\nLabels: 0\n\nSample: Falls are a common adverse event during hospitalization of older adults , and few interventions have been shown to prevent them .\n\nLabels: 0\n\nSample: Evaluation of oral treatment in vaginitis and vaginosis using Itraconazol and sechidazol , in comparison to topic treatment using vaginal ovules of acetonido of fluocinolona 0.50 mg , nistatina 100,000 U and metronidazol 500 mg .\n\nLabels: 3\n\nSample: The microbiologic parameters were also statistically significant .\n\nLabels: 4\n\nSample: A single-injection sciatic nerve block can reduce severe pain on the day of the surgery , whereas a continuous sciatic nerve block reduces moderate pain during mobilization on the first 2 postoperative days .\n\nLabels: 1\n\nSample: Agreement between subjective assessments was highest for GPs ' usual assessment ( agreement 73 % ; kappa 0.47 ; p = 0.03 ) , which also gave the highest area under the ROC curve ( 0.75 , 95 % CI : 0.52-0 .98 ) .\n\nLabels: 4\n\nSample: Intervention reduced both infection intensity and prevalence in the intervention arm as compared to control arm .\n\nLabels: 1\n\nSample: 16 patients ( 5 % ) in the TMP-SMX plus placebo group and 21 patients ( 7 % ) in the TMP-SMX plus doxycycline group developed culture-confirmed recurrent melioidosis ( HR 0.81 ; 95 % CI 0.42-1 .55 ) .\n\nLabels: 4\n\nSample: After treatment the scores of SS-QOL and FSS increased in the 3 groups , especially in the CM treatment group , showing significant difference ( P < 0.05 ) .\n\nLabels: 4\n\nSample: Patients received candesartan ( target of 32 mg once daily ) or matching placebo for 2 to 4 years .\n\nLabels: 4\n\nSample: Treatment with the antihistamine had no influence on PC20 , except when histamine was used as the bronchoconstricting agent .\n\nLabels: 4\n\nSample: To determine the efficacy of acetazolamide in the treatment of patients with acute mountain sickness and the effect of the drug on pulmonary gas exchange in acute mountain sickness .\n\nLabels: 3\n\nSample: However , patients treated with prednisone > or = 5 mg/day plus MTX had greater loss of BMD in the lumbar spine than patients treated with a similar dose of prednisone without MTX ( difference -8.08 % over 3 years ; p = 0.004 ) .\n\nLabels: 4\n\nSample: Two patients receiving dalteparin developed DVT ( one symptomatic and one asymptomatic ) .\n\nLabels: 4\n\nSample: Outcome variables were measured at the start and end of the study at subjects ' homes by a dietitian blinded to treatment assignment .\n\nLabels: 2\n<Assistant>Appreciated. I'll retain these important details.", "[Dialogue between User and Assistant on 2024-01-08 00:00]\n<User>Please observe these classification examples and their associated labels:\n\nSample: A double-blind , dose escalating tolerability study of DP-b99 in normal ( young - aged between 18 and 40 years and elderly - aged between 65 and 85 years ) healthy adult male volunteers was conducted .\n\nLabels: 2\n\nSample: A total of 16492 patients with type 2 diabetes mellitus and a history of , or at risk of , cardiovascular events were randomized to saxagliptin or placebo ( mean follow-up , 2.1 years ) .\n\nLabels: 4\n\nSample: Outcomes were assessed at baseline , 6 and 12 months .\n\nLabels: 2\n\nSample: The gauge of the needle ( # 30 ) , the irrigation cycles ( ie , 5 mL NaOCl , 5 mL 15 % EDTA , and 5 mL NaOCl ) , the irrigant flow rate ( 5 mL/min ) , and needle depth placement ( 1 mm from the working length [ WL ] ) were experimental constants .\n\nLabels: 2\n\nSample: The study had an open randomized crossover design with 1 week run-in without treatment and the two treatment periods of 2 weeks each .\n\nLabels: 2\n\nSample: The decreases in SBP and DBP according to 24-hour ABPM from baseline to week 8 were significant and similar in both groups .\n\nLabels: 4\n\nSample: Platelet factor 4 activity and platelet counts showed no differences among the groups .\n\nLabels: 4\n\nSample: The groups did not differ in total direct costs ( 3786/woman in psychoeducative group and 3830/woman in control group ) , nor in life satisfaction or general well-being .\n\nLabels: 4\n\nSample: Future influenza vaccine studies in elderly people should be based on subtype or lineage-specific endpoints .\n\nLabels: 1\n\nSample: No severe adverse effects were reported .\n\nLabels: 4\n\nSample: The notable exception was for objectively assessed troop PA , wherein girls in intervention troops accumulated significantly less sedentary ( x2 = 6.3 , p = .011 ) , significantly more moderate ( x2 = 8.2 , p = .004 ) , and more moderate-to-vigorous physical activity , ( x2 = 18.4 , p < .001 ) , than girls in control troops .\n\nLabels: 4\n\nSample: Excluding participants with baseline CVD ( 3.4 % ) , the HRs ( 95 % CIs ) for CHD and stroke were 0.94 ( 0.86-1 .02 ) and 1.02 ( 0.90-1 .17 ) , respectively .\n\nLabels: 4\n\nSample: Beliefs that changed were ( 1 ) perceived susceptibility to stroke , and ( 2 ) perceived benefit of exercise to reduce risk .\n\nLabels: 4\n\nSample: The rate of non-life-threatening surgical complications did not differ between the groups ( p = 0.98 ) .\n\nLabels: 4\n\nSample: Therefore , changes in the TG levels shown by the stratification may be related to the apolipoprotein E changes that are observed following CEE replacement .\n\nLabels: 1\n\nSample: Flapless implant placement yielded improved clinical , radiographic , and immunological outcomes compared with flapped implantation .\n\nLabels: 1\n\nSample: Our aim was to investigate the effects of reconstituted high-density lipoprotein ( rHDL ) infusions on plasma high-density lipoprotein ( HDL ) anti-inflammatory properties and ex vivo cholesterol efflux in patients with type 2 diabetes .\n\nLabels: 3\n\nSample: There was no significant difference between intraoperative subtraction pachymetry and postoperative AS-OCT measurements for femtosecond flaps ( P = .38 ) .\n\nLabels: 4\n\nSample: The main outcome measures were : changes in blood pressure ; blood total cholesterol ; diet ; activity level and health related quality of life 1 month and 4 months after the end of treatment .\n\nLabels: 2\n\nSample: The subjects were randomized in three groups to receive one of following supplementation ; quercetin + vitamin C ( 166 mg +133 mg/capsule ) , alpha-lipoic acid ( 300 mg/capsule ) or placebo for 4 weeks ( 3 capsules/day ) .\n\nLabels: 2\n\nSample: In a randomized , double-blind , parallel-group adaptive treatment trial , the authors identified 222 cigarette smokers who failed to show a reduction of more than 50 % in smoking after 1 week of nicotine patch treatment .\n\nLabels: 2\n\nSample: Dose-response curves show biphasic shocks to have higher cumulative success rates at all energies tested .\n\nLabels: 4\n\nSample: All patients were evaluable for efficacy .\n\nLabels: 4\n\nSample: No such difference was seen in the higher LDL cholesterol subgroups .\n\nLabels: 4\n\nSample: The primary efficacy parameter was time to resolution of diarrhea , defined as the first day of 2 consecutive days when the patient had hard or formed stools ( any number ) or < or = 2 stools of loose or watery consistency .\n\nLabels: 2\n\nSample: Restricted unilateral motor and sensory block was achieved in 30 % and 12.5 % of patients , respectively .\n\nLabels: 4\n\nSample: During the ensuing 24 months , repeated chelation therapy was administered weekly to 32 patients with high-normal body lead burdens ( at least 80 microg but less than 600 microg ) unless on repeated testing the body lead burden fell below 60 microg ; the other 32 patients served as controls and received weekly placebo infusions for 5 weeks every 6 months .\n\nLabels: 2\n\nSample: Sucralfate , a basic aluminum salt of sucrose sulfate , is supposed to have an antibacterial activity and is said to reduce the bacterial density of H. pylori .\n\nLabels: 3\n\nSample: To determine if treatment with an oral pancaspase inhibitor could reduce serum AST and ALT in patients with HCV .\n\nLabels: 3\n\nSample: No difference was seen in hip function , general complications , or mortality between the groups .\n\nLabels: 4\n\nSample: The primary analysis did not support the study hypothesis .\n\nLabels: 1\n\nSample: The effect of finasteride on PSA has been widely reported .\n\nLabels: 0\n\nSample: This was a single-centre randomized control trial ( RCT ) of 1,608 patients ( IVR = 803 ; usual care = 805 ) .\n\nLabels: 2\n\nSample: IRI clearance with the PS membrane was significantly higher than that with the CTA and PMMA membranes .\n\nLabels: 4\n\nSample: Of the 181 patients randomised , 92 and 89 were included in the intervention and the control groups , respectively .\n\nLabels: 2\n\nSample: Two randomized , double-blind , 4-week , multi-centre trials with identical methodology compared once-daily esomeprazole , 40 mg ( n = 241 ) or 20 mg ( n = 234 ) , with placebo ( n = 242 ) for the rigorous end-point of complete resolution of heartburn .\n\nLabels: 2\n\nSample: The primary objective is to evaluate superiority of the proposed HLA matching strategy in comparison to random graft assignment with respect to the primary endpoint ` time to first endothelial graft rejection ' .\n\nLabels: 2\n\nSample: In this study , we helped patients , who underwent 1-level , first-time lumbar microdiscectomy have a postoperative pain-free and comfortable period by using epidural meperidine-impregnated AFFGs .\n\nLabels: 1\n\nSample: pcCRC is associated with a significantly shorter OS and PFS as compared with other manifestations of mCRC .\n\nLabels: 1\n\nSample: Subgroup analyses among patients with moderately heavy or heavy work showed that the prevalence of low back pain during the previous 12 months decreased more in the intervention than in the control group .\n\nLabels: 4\n\nSample: The median macrophage volume fractions for polyethylene-on-zirconia bearing material ( n = 15 ) , CoCr-on-CoCr ( n = 9 ) , and alumina-on-alumina ( n = 11 ) were 0.02 , 0.04 , and 0.004 , respectively .\n\nLabels: 4\n<Assistant>I understand. I'll keep this in mind.", "[Dialogue between User and Assistant on 2024-01-09 00:00]\n<User>Here are some examples with classification labels to remember:\n\nSample: Assessment of the usefulness of antibiotic prophylaxis in inguinal hernioplasty .\n\nLabels: 3\n\nSample: Furthermore , we observed decreases in FAS mRNA expression and serum triglycerides as a result of a high calcium intake .\n\nLabels: 1\n\nSample: 24 patients requiring Intensive Care after major surgery or because suffering from severe head injury or major neurological impairment .\n\nLabels: 2\n\nSample: All dual-energy X-ray absorptiometry scans were analysed centrally , blinded by arm .\n\nLabels: 2\n\nSample: Primary outcome measures were prolonged abstinence from weeks 4-12 , 4-26 and 4-52 .\n\nLabels: 2\n\nSample: Tumor volume ( TV ) is one of the main reported factors determining the outcome of treatment in head-and-neck carcinomas .\n\nLabels: 3\n\nSample: Comprehensive drug use data ( urine specimens and self-report ) and other health and psychosocial data were collected weekly during treatment and research interviews at baseline , week 10 and week 22 .\n\nLabels: 2\n\nSample: During the trial , intensification increased most during the first year and then declined .\n\nLabels: 4\n\nSample: However , interruption of CPAP therapy is common and is associated with a decline in daytime function .\n\nLabels: 0\n\nSample: Body weight loss and increased physical fitness were the most important determinants of improved glucose tolerance and insulin sensitivity .\n\nLabels: 1\n\nSample: The 12-month estimated adjusted hazard for relapse and need for retreatment for the botulinum toxin group was 2.69 times that of the pneumatic dilatation group ( 95 % confidence interval ; 1.18-6 .14 ) .\n\nLabels: 4\n\nSample: Patients with AF received 4g intravenous magnesium sulfate or normal saline in a randomized , double-blinded fashion .\n\nLabels: 2\n\nSample: During the 40-d period , subjects expended an estimated 4682 2874 kcal just by playing AVG .\n\nLabels: 4\n\nSample: Reports have demonstrated that nutrient supplements , in particular vitamin-B complex ( Vit-B ) , can positively influence wound healing processes .\n\nLabels: 0\n\nSample: Kidney donors will accept a higher risk of death than is currently quoted , especially if risks are presented in terms of chance of survival .\n\nLabels: 1\n\nSample: Data were analyzed by group , as well as merged once all had received exercise intervention .\n\nLabels: 2\n\nSample: From March 1994 to March 1998 , 525 breast cancer patients ( estimated relapse risk > 70 % within 5 years with standard therapy ) were included in the Scandinavian Breast Group 9401 study .\n\nLabels: 2\n\nSample: To investigate the effect of a six-week programme of moderate intensity exercise on daytime ambulatory blood pressure ( 10.00 am to 10.00 pm ) among unmedicated , sedentary adults aged 25 years to 63 years with office blood pressure of 150 mmHg to 180 mmHg systolic and/or 91 mmHg to 110 mmHg diastolic .\n\nLabels: 3\n\nSample: In group 1 , high intensity S1 stimulation shortened the atrial effective refractory period most prominently at the site of S1 : ( mean + / - SD ) 13.3 + / - 6.4 % ( p < 0.001 ) , 8.1 + / - 3.8 % ( p < 0.001 ) , 4.8 + / - 4.3 % ( p < 0.001 ) , 3.7 + / - 4.7 % ( p < 0.001 ) and 0.5 + / - 2.6 % at 0 , 7 , 14 , 21 and 28 mm from the S1 site , respectively .\n\nLabels: 4\n\nSample: The latter may be due to a specific pharmacodynamic mechanism mediated through angiotensin II AT1 receptors .\n\nLabels: 1\n\nSample: To provide practical clinical guidelines to doctors who have no hemodynamic monitoring facilities in performing escharectomy during the shock period in extensively burned patients .\n\nLabels: 3\n\nSample: In nine catheter malpositions , undetected by ECG guidance , the angle between the catheter tip and the lateral wall of the superior vena cava exceeded 40 degrees on CXR .\n\nLabels: 4\n\nSample: There was no significant difference in terms of the hospital stay , complication rate , and continence function ; however , the mean pain intensity in the first postoperative week was significantly less in the PPH group ( 4.1 vs. 5.7 , P = 0.02 ) .\n\nLabels: 4\n\nSample: It is a simple randomized , clinical trial including 200 patients with acute appendicitis who were divided into two groups ( A1 and A2 ) .\n\nLabels: 2\n\nSample: With consumption of the whey drink , the AUCs were 56 % smaller ( glucose ; P < 0.05 ) and 60 % larger ( insulin ; P < 0.05 ) , respectively , than with the reference drink .\n\nLabels: 4\n\nSample: The optimal cut-off point for the MCIC for the HIT-6 was -8 points , on a total scale range of 42 points .\n\nLabels: 4\n\nSample: The rate of ADEs decreased from 25.8 to 18.3 per 100 patients per year in the intervention group .\n\nLabels: 4\n\nSample: Prospective randomized clinical trial of patients with bilateral operative cataract .\n\nLabels: 2\n\nSample: ED was defined as a Paediatric Anesthesia Emergence Delirium scale ( PAED ) 10 points .\n\nLabels: 2\n<Assistant>I've processed this information and will remember it.", "[Dialogue between User and Assistant on 2024-01-10 00:00]\n<User>Study these classification examples and pay attention to the categories:\n\nSample: Patients with locally advanced squamous cell carcinoma ( SCC ) of the esophagus were randomly allocated to either induction chemotherapy followed by chemoradiotherapy ( 40 Gy ) followed by surgery ( arm A ) , or the same induction chemotherapy followed by chemoradiotherapy ( at least 65 Gy ) without surgery ( arm B ) .\n\nLabels: 2\n\nSample: Baseline percentages of patients with moderate and severe hfPGA scores were 76 % and 24 % , respectively , for the adalimumab group and 74 % and 26 % , respectively , for the placebo group .\n\nLabels: 4\n\nSample: Our goal was to determine the most efficient measure of dental amalgam exposure for use in analyses concerning U-Hg in children .\n\nLabels: 3\n\nSample: To compare four different methods of handling missing data in a 60-week placebo controlled anti-obesity drug trial on topiramate .\n\nLabels: 3\n\nSample: The inclusion and exclusion criteria , definitions , and treatment protocols are those reported by the 2012 Expert Consensus Statement on catheter and surgical ablation of atrial fibrillation .\n\nLabels: 2\n\nSample: We evaluated the effect of the third year of SLIT in comparison to the second year .\n\nLabels: 3\n\nSample: Karnosfky status was required to be greater than 60 .\n\nLabels: 2\n\nSample: The total effective rate for clinical symptoms was significantly higher in Group A than in Group B with statistical difference ( 93.3 % vs 73.3 % , P < 0.05 ) .\n\nLabels: 4\n\nSample: After two years , two of the 113 restorations in the early treatment group required further treatment because of penetrating stain at a margin .\n\nLabels: 4\n\nSample: The ratio of randomisation depended on how many clinics were in each of nine strata .\n\nLabels: 2\n\nSample: To determine whether ondansetron is effective in treating the pruritus of cholestasis .\n\nLabels: 3\n\nSample: Resolution of all abdominal and gastrointestinal symptoms was considered a good response .\n\nLabels: 2\n\nSample: The control group was treated with a conventional arm rehabilitation programme without NMES .\n\nLabels: 2\n\nSample: We assessed whether DAPT continuation beyond 1 year after coronary stenting is beneficial .\n\nLabels: 0\n\nSample: At least 97.5 % of DTaP-Hib recipients had seroprotection against diphtheria , tetanus and Hib , and response to acellular pertussis antigens one month after primary vaccination .\n\nLabels: 4\n\nSample: Sertraline conferred significantly greater prophylaxis against depression recurrence than did placebo ( hazard ratio = 0.51 ; 95 % confidence interval , 0.31-0 .85 ; P = .02 ) .\n\nLabels: 4\n\nSample: Five of 18 patients in the clonidine-bupivacaine group received no postoperative morphine , compared to 1 of 15 in the bupivacaine group .\n\nLabels: 4\n\nSample: Seventy-two patients with malignant ascites were divided into two study groups .\n\nLabels: 2\n\nSample: However , our results did not show any impairment of learning of extinction after the administration of alcohol .\n\nLabels: 4\n\nSample: At the last visit , in the combined therapy subgroup , 1.7 % of patients showed no clinical improvement , 26.7 % showed a marked clinical improvement , and 71.6 % showed complete remission .\n\nLabels: 4\n\nSample: Acceptance of treatment and relatively high dropout rates pose a major problem for research in the treatment of anorexia nervosa .\n\nLabels: 1\n\nSample: Infants in the experimental group had significantly higher energy intake for the entire 7-day study period and achieved 90 kcal/kg per day ( 1 kcal = 4.184 kJ ) significantly sooner ( 7.38 + / - 3.381 days vs 9.44 + / - 3.578 days ) .\n\nLabels: 4\n\nSample: Effectiveness was determined by femoral vascular complications rate .\n\nLabels: 2\n\nSample: Prospective controlled multicentre trial with four months ' follow-up .\n\nLabels: 2\n\nSample: An important risk factor for cardiovascular disease , low heart rate variability , often has been found in depressed patients and has been associated with impulsivity .\n\nLabels: 0\n\nSample: The primary endpoint was the average dysphagia score during the first 6 mo. .\n\nLabels: 2\n\nSample: The objective of this study was to analyze the plasma concentration of 50 % enantiomeric excess ( S75R25 ) 0.5 % bupivacaine combined with 1:200,000 epinephrine in the parasacral ( PS ) and infragluteal ( IG ) sciatic nerve block ( SNB ) .\n\nLabels: 3\n\nSample: The aim of this study was to investigate the hypothesis that prevention of surgical site infection ( SSI ) is equally effective when patients receive single-dose ( SD ) or three-dose antibiotic prophylaxis with second-generation cephalosporin and metronidazole in elective colorectal surgery .\n\nLabels: 0\n\nSample: The composite of all-cause mortality and nonfatal cardiovascular event rate was not different in the OL-HDF and in the high-flux HD groups .\n\nLabels: 1\n\nSample: Landmark analysis and Cox proportional-hazards models showed that wall motion index ( WMI ) was a significant prognostic factor until 10 years of follow-up with hazard ratios ranging between 0.74 [ confidence interval ( CI ) 0.71-0 .78 ] and 0.90 ( CI 0.82-0 .98 ) associated with a 12 % improvement in left ventricular ejection fraction ( 0.4 WMI units ) .\n\nLabels: 4\n\nSample: Differences for the 2 groups in each treatment arm were not significant .\n\nLabels: 4\n\nSample: Patients in the behavioral , but not the drug counseling , treatment also received incentives contingent on submitting cocaine-free urine specimens .\n\nLabels: 2\n\nSample: The Term Breech Trial compared the safety of planned cesarean and planned vaginal birth for breech presentations at term .\n\nLabels: 0\n\nSample: However , the rate of crossover was significantly higher among patients randomized to receive CsA-based therapy ( 27.5 % vs. 9.3 % ; P < 0.001 ) .\n\nLabels: 4\n\nSample: Patients receiving low-dose spinal anesthesia were eligible for PACU discharge earlier than those receiving the standard dose ( P = 0.0036 ) .\n\nLabels: 4\n\nSample: Of the aspirin-treated subjects , 20 % were pain free at 2 hours versus only 6 % of placebo-treated subjects .\n\nLabels: 4\n\nSample: We examined the efficacy and safety of the serotonin selective reuptake inhibitor sertraline hydrochloride in patients with panic disorder .\n\nLabels: 0\n\nSample: 42 susceptibles with negative anti - HAV were selected in Zhengding , Hebei province .\n\nLabels: 2\n\nSample: Device failure was defined as buckling of the sheath that prevented adequate placement , kinking of the sheath after removal of the obturator or difficulty in passing instruments through the sheath .\n\nLabels: 2\n\nSample: On the other hand the ON-pathway as measured by dark vision and the scotopic ERG was affected as well .\n\nLabels: 1\n\nSample: No differences were found in symptom severity , individual symptom items , and in serious adverse events between the two arms .\n\nLabels: 4\n\nSample: Measurements take place at baseline ( entry of the study ) , after three months ( end of the exercise program ) and after six months ( follow-up ) .\n\nLabels: 2\n\nSample: Patients were randomly assigned to receive 10 days of treatment with prednisolone , acyclovir , both agents , or placebo .\n\nLabels: 2\n\nSample: Six schools were randomised to receive shoes and standard care ( deworming with albendazole and health education ) and six control schools to receive standard care only .\n\nLabels: 2\n\nSample: No significant difference between the 2 groups was found in the percentage of patients whose serum creatinine ( SCr ) test results returned to normal within 28 days ( P > 0.05 ) , nor were there a significant difference in safety evaluation ( P > 0.05 ) .\n\nLabels: 4\n\nSample: At discharge , IGFBP-1 was unchanged , but insulin was elevated compared with preoperative levels .\n\nLabels: 2\n\nSample: Statin Choice is a decision aid about taking statins .\n\nLabels: 0\n\nSample: Four hours of HCO-IHD accomplished a greater decrease in plasma IL-6 levels ( -30.3 % ) than 4 hours of HF-IHD ( 1.1 % ; P = 0.05 ) .\n\nLabels: 4\n\nSample: Fracture type significantly affected the performance of the Fixion nail .\n\nLabels: 1\n\nSample: The aim of this study was to assess and compare efficacy of cefuroxime and co-amoxiclav in the treatment of acute sinusitis in an Iranian sample population .\n\nLabels: 3\n\nSample: The aim of the present study was to quantitatively analyze peri-implant sulcular fluid ( PISF ) nitrite levels in a longitudinal study design to evaluate the potential changes in nitric oxide metabolism in relation to the clinical status of the peri-implant site and the loading style of the dental implants .\n\nLabels: 3\n\nSample: Fifty growing patients ( 26 males and 24 females ) with skeletal Class III and mandibular prognathism were selected .\n\nLabels: 2\n<Assistant>Wonderful. I'll remember these key points."]
[{"question": "Sentence: clinicaltrials.gov identifier : NCT00327691 .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Treatment with prolonged ( > or = 14 d ) mechanical ventilation was reduced from 99 of 212 ( 46.7 % ) to 72 of 208 ( 34.6 % ) ( p = 0.01 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: AS03-adjuvanted CC-H5N1 elicited a homologous hemagglutination inhibition antibody response that satisfied immunogenicity criteria 21 days after dose 2 and persisted at month 12 .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Of the women who participated in the randomized trial 74 % ( 482 of 655 ) were enrolled in the followup study .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The outcomes were the composite of death or myocardial infarction ( MI ) and its individual components .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Single doses of placebo/Seretide 250 ( total dose ex valve fluticasone 2000 mcg/salmeterol 200 mcg ) were administered via the devices .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: No significant difference ( P = 0.49 ) in mean URR was detected between sessions performed through femoral ( n = 213 ; 50.9 % ) and jugular ( n = 182 ; 49.5 % ) dialysis catheters .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The dose-response curves for neostigmine - and edrophonium-assisted antagonism of rocuronium bromide neuromuscular blockade for the single twitch and TOF ratio were not parallel .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Patients in the autotransfusion group had a significantly higher 24-hour postoperative hemoglobin concentration ( 11.9 g/dL ; SD , 1.41 g/dL ) than those in the control group ( 10.5 g/dL ; SD , 1.37 g/dL ) ( mean difference , 1.02 g/dL ; 95 % confidence interval , 1.60-0 .44 g/dL ; P = .0007 ) , as well as a 20 % reduction in the frequency of homologous blood product use ( 11/31 vs 5/30 ; P = .095 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Moreover , leptin and ghrelin secretions were not responsible for BMI changes .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: There was no significant difference between two groups in gender , age , disease course and volume of residual cavity ( P > 0.05 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Poor responders had lower blood pressure , more frequent diabetes , long-term use of loop diuretics , poorer baseline renal function , and lower urine output ( all P < .01 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Patients treated with dapsone gel combined with adapalene showed a significantly better response in reduction in non-inflammatory and total acne lesion count than those who received the moisturizer combination .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: There were 480 probe sets , corresponding to 449 genes , differentially expressed between TIA and controls ( false discovery rate correction for multiple comparisons , p 0.05 , absolute fold change 1.2 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: With longer follow-up , four cycles of TC was superior to standard AC ( DFS and OS ) and was a tolerable regimen in both older and younger patients .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Statistical analysis failed to demonstrate differences for 38/39 variables assessed at baseline .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The primary endpoint , progression-free survival ( PFS ) , was calculated from randomization date .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Immune responses to rotavirus were assessed by serum and stool IgA , and by serum 89-12 neutralising titres .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: PONV was significantly less likely in the propofol group at the early time points ( in the operating room and postanesthesia care unit ) but not at later time points ( postoperative day 1 or 2 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: If successful , this intervention could be disseminated to the entire U.S. Military as this project is designed to overcome the barriers and utilize the facilitators for weight loss that are unique to a military population .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Level III nursery at a Midwestern hospital .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Both of the menstrual management methods evaluated were well tolerated by subjects .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: A 50 % improvement was achieved in 29 , 27 , 26 , and 31 % of infliximab plus methotrexate in the same treatment groups , compared with 5 % of patients on placebo plus methotrexate ( p < 0.001 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Medical costs were twice as high for screened subjects , with considerable between-subject variability .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Chronic liver disease leads to fibrosis and cirrhosis of the liver .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: The adverse reactions were similar in the two treatment groups .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: There was no statistically significant difference between the lateral condensation , Touch 'n Heat + Ultrafil , and Microseal groups .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: This occurred in a patient receiving 5 microg/kg daily who experienced vasospasm and a coagulopathy resulting in arterial thrombosis .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: King Chulalongkorn Memorial Hospital .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: To study the effect of insulin treatment in combination with metformin or an insulin secretagogue , repaglinide , on glycaemic regulation in non-obese patients with type 2 diabetes .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: Although previous studies have attempted to identify predictors of outcome in schizophrenia , few have prospectively studied first episode patients for an adequate follow-up period .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: The primary outcomes are the frequency of antibiotic associated and C. difficile diarrhoea during 8-12 weeks follow-up .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: A cyclodextrin solution formulation of budesonide has been developed .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Forty eyes undergoing peribulbar anesthesia with 7 mL of anesthetic solution without vasoconstrictor were randomly divided into two groups : ropivacaine ( n = 20 ) and bupivacaine ( n = 20 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: The otamixaban dose selected at interim analysis was an intravenous bolus of 0.080 mg/kg followed by an infusion of 0.140 mg/kg per hour .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Given the extensive reach of mobile devices , this pilot study demonstrates the need for larger-scale testing of similar programs to address obesity-related behaviors in high-risk youth .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Sixty one mild-to-moderate degree CTS patients , aged 27-67 were randomly assigned to acupuncture ( Acu ) and night splinting ( NS ) groups .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: As determined by Kaplan-Meier analysis , the projected recurrence rate after 10 years in all surviving patients is 36 % ( 95 % CI , 23 % to 59 % ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The aim of the study was to examine the effect of oral phosphate and alendronate therapy on PTH sensitivity , bone turnover , and bone mineral density ( BMD ) in AGHD patients .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: All children were randomly assigned to receive either albendazole ( 15 mg/kg / day ) or placebo for 28 days .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: It was effective in spreading the health message conveyed by the campaign , regardless of the level and kind of emotive impact evoked .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: We aimed to determine the effects of treatment with intravenous immunoglobulin on bacterial infections in patients with hypogammaglobulinemia ( HGG ) after lung transplantation .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: women , but the data is insufficient to draw definite conclusions regarding the estrogenic effect .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: This study was conducted from October 1 , 2004 , through May 31 , 2008 , in the emergency department of an urban , tertiary care children 's hospital .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: A total of 171 patients received adalimumab + MTX ( mean dose , 6.20.8 mg/week ) and 163 patients received MTX alone ( mean dose , 6.60.6 mg/week , p < 0.001 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: All changes favored the CMHA-only condition .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Survival analyses were used to evaluate continuous outcomes , and chi2 and logistic regression analyses were used to evaluate discrete outcomes .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: We revised our complications , microorganism most common in the infectious complications , and their sensibility .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: The adverse event profile was similar between red clover isoflavones , and placebo and endocrine status did not differ .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Twenty-three patients undergoing primary elective coronary revascularization were randomized to one of two different techniques of myocardial protection .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Plasma kinetics of lansoprazole were determined .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Healthy 2-month old infants were randomized to receive 2 ( at the ages of 4 and 6 months ) or 3 ( at the ages of 2 , 4 , and 6 months ) PCV7 doses and a booster dose ( at the age of 12 months ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Patients were then retreated with 10 mg/kg CDP571 or placebo every 8 or 12 weeks to assess subsequent dosing intervals .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Participants received either 20 mg/day of policosanol or placebo for 12 weeks , followed by a 4-week washout and crossover to the other arm .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: ( 6 ) Use of the Group Sequential Double Triangular Test with sufficient power to determine superiority , inferiority , or equivalence .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: At discharge , patients and caregivers completed a satisfaction survey .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Before treatment all patients displayed signs of uterine hyperactivity as judged by a high resting pressure ( 7.5 + / - 0.4 kPa ) , high active pressure ( 24.0 + / - 0.8 kPa ) , and a high frequency of pressure cycles ( 13.3 + / - 0.5 contractions per 0.5 hour ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Such effects have been hypothesized to play a key role in the development of later therapeutic responses to treatment .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: It was hypothesised that the airway response to inhaled allergen after exposure to a combination of 400 ppb nitrogen dioxide ( NO2 ) and 200 ppb sulphur dioxide ( SO2 ) is increased 24-48 hours after exposure .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: The interrater reliability for the summarised coding system was fair , but a larger sample of medication regimens is needed to assess the non-summarised quality use of medicines coding system .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: In recent years , the cryoballoon-based technique is increasingly used as a promising alternative with a short learning curve .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: The averaged IMR of the 36 patients with STEMI after primary PCI was 31.6 U.\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: There were no serious adverse events .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Using well-known risk factors for restenosis and target lesion revascularization ( TLR ) , risk groups were formed to examine the absolute differences between PES and BMS .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Azithromycin ophthalmic solution in combination with warm compresses provided a significantly greater clinical benefit than warm compresses alone in treating the signs and symptoms of posterior blepharitis .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: The purpose was to determine the effects of small ( approximately 500 ml ) versus large ( approximately 1000 ml ) tidal volumes given with paediatric versus adult self-inflatable bags and approximately 50 % oxygen on respiratory parameters in patients during simulated basic life support ventilation .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: There was no significant changes in IL-1 , ICAM-1 and P-selectin , and a decrease in E-selectin concentrations after the procedures ( 52.0 + / - 17.5 ng/ml to 49.3 + / - 18.7 ng/ml ; p = 0.009 ) was observed .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: In addition , the intraoperative propofol C ( e ) in the lidocaine group during the periods of intubation , organ resection , closing of chest cavity and extubation was significantly lower ( P < 0.05 , n = 20 per group ) than that in the control group under the same hypnotic depth .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Milk and dairy products are the most important iodine sources .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: There is a trend for topiramate to be superior to naltrexone on critical measures of drinking ; however , the study did not have adequate statistical power to establish this fact .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: According to strict , predefined criteria for response , 68 % of desipramine-treated subjects and no subjects in the placebo group were considered positive responders .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Because of the small sample size , no detailed comparison of adverse event rates were warranted .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: To address the question of the optimal application time , we randomly assigned patients ( pts ) to pegfilgrastim on day + 1 ( Peg1 ) or day + 4 ( Peg4 ) after AHSCT .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: No difference in the number of children who went to sleep was seen .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Improvement was defined as a 17-item Hamilton Rating Scale for Depression ( HAM-D-17 ) score reduction of > or = 20 % .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: In a substudy of patients with coronary artery disease and left ventricular dysfunction who were enrolled in a randomized trial of medical therapy with or without CABG , we used single-photon-emission computed tomography ( SPECT ) , dobutamine echocardiography , or both to assess myocardial viability on the basis of prespecified thresholds .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Treatment with ZSP and retinamide decreased malignant transformation rate of severe dysplasia by 52.2 % and 43.2 % , respectively after 5 years of treatment .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The hemodynamic effects of mild blood cooling should be balanced against a potentially higher risk of cold discomfort .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: ClinicalTrials.gov Identifier : NCT00825812 .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Ibudilast is generally well tolerated in healthy adults when given as a single oral dose of 30 mg followed by 30 mg b.i.d. ( 60 mg day ( -1 ) ) for 14 days .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Expectation of pain at mammography was predictive of non-attendance .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The mean weight of the prostate was not significantly different statistically between the 2 groups at 63 + / - 23 g and 64 + / - 19 g in groups 1 and 2 , respectively ( P = .8 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Assessments were performed at baseline ( n = 82 ) and after 6 weeks ( T1 ; n = 75 ) and 6 months ( T2 ; n = 67 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: A total of 15 patients received placebo ( group A ) , 12 patients 500 microg icatibant ( group B ) and 14 patients 2000 microg icatibant ( group C ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: At the 1 year analysis , proinsulin levels decreased significantly in all groups receiving active intervention and were no longer associated with SLC30A8 genotype ( p = 0.86 ) after adjustment for insulin at baseline and 1 year .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Data were collected 4 times : ( 1 ) 1 week before the intervention , ( 2 ) the 6th session of the intervention , ( 3 ) the 12th session of the intervention , and ( 4 ) 1 month after the final session .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Mitral regurgitation has been associated with a poor prognosis in patients treated with thrombolytic therapy for AMI .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: There were fewer gastrointestinal adverse events with sevelamer carbonate .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The efficacy of long-pulsed Nd : YAG 1064 nm laser intervention against affected toenails is superior to that against fingernails .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: From the 6505 patients who were randomized in SHIFT , baseline creatinine and at least one follow-up measurement were available in 6160 patients .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: High concentrations of total omega-3 fatty acids , eicosapentaenoic and docosahexaenoic acids in red blood cells , and ornithine in plasma , all were associated with a significantly lower incidence of rejection , whereas high total omega-6 fatty acids were associated with a high rejection rate .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Left ventricular end-diastolic volumes were slightly lower in Group A than in Group B , although statistically this was not significant .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Three pediatric patients were excluded .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: To compare the antihypertensive efficacy and systemic tolerability of valsartan , a new angiotensin II receptor antagonist , with placebo and with an angiotensin converting enzyme ( ACE ) inhibitor , enalapril .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: Treatment was continued until complete remission plus two cycles , or until disease progression .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: At monthly intervals , corticosteroid dosages were reduced by algorithm in patients whose SLE Disease Activity Index ( SLEDAI ) score was stable or improved .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: The MLXIPL-rs3812316 was associated with lower baseline triglycerides ( P = 5.510 ( -5 ) ) and lower hypertriglyceridemia ( odds ratio , 0.73 ; 95 % confidence interval [ CI ] , 0.63-0 .85 ; P = 1.410 ( -6 ) in G-carriers versus CC ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Analyses were by intention-to-treat and per-protocol .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: The primary efficacy variable was the absolute change in central systolic BP ( CSBP ) from baseline to the final examination , measured by radial artery applanation tonometry and analyzed by parametric analysis of covariance .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Blood was sampled at regular time intervals .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}]