["[Dialogue between User and Assistant on 2024-01-01 00:00]\n<User>Please memorize these classification examples and their labels:\n\nSample: The steroid recipients reported more adverse events .\n\nLabels: 4\n\nSample: The LF diet was associated with significant changes in fat-free body mass and energy expenditure from physical activity compared with the HF diet .\n\nLabels: 1\n\nSample: In the treatment group , significant increases in peak oxygen consumption , exercise time and metabolic equivalents ( MET ) levels were attained ( P = 0.001 , P = 0.001 , P = 0.003 , respectively ) .\n\nLabels: 4\n\nSample: CI-994 , an oral histone deacetylase inhibitor , has antineoplastic activity and synergism with gemcitabine preclinically .\n\nLabels: 0\n\nSample: To determine pharmacokinetic profiles of two times a day and three times a day dosage regimens of Endometrin , a micronized progesterone vaginal insert for luteal support in assisted reproductive technology , compared with a gel .\n\nLabels: 3\n\nSample: Serial blood samples were collected up to 120 hours after drug administration for pharmacokinetic analysis and the assessment of DPP IV activity , and blood samples were collected up to 2 hours after each meal until the next morning of drug administration to evaluate active GLP-1 , glucose , and insulin levels .\n\nLabels: 2\n\nSample: When aggressive treatment aimed at substantial reduction in IOP from baseline is used , loss of VF can be seen to be minimal in general .\n\nLabels: 1\n\nSample: The same pattern was observed in the infliximab plus MTX group , although the proportions of joints with damage at week 54 were generally larger in the placebo plus MTX group .\n\nLabels: 4\n\nSample: Participants were alloted into 3 groups which differed in RS rates to generate numbers : 1 , 2 and 4 seconds to generate each number .\n\nLabels: 2\n\nSample: alpha-Sarcoglycan deficiency results in a severe form of muscular dystrophy ( limb-girdle muscular dystrophy type 2D [ LGMD2D ] ) without treatment .\n\nLabels: 3\n\nSample: Patients stabilized on fosinopril 20 mg/day were randomized to receive either HCTZ 12.5 mg od or indapamide 2.5 mg od for 8 weeks , then crossed over to the alternate therapy for a further 8-week period .\n\nLabels: 2\n\nSample: They presented less akathisia and less medication intake .\n\nLabels: 4\n\nSample: Appropriateness of prescribing was examined according to different risk groups based on the Anatomical Therapeutic Chemical Classification System ( ATC codes ) .\n\nLabels: 2\n\nSample: Both extracts containing 3.0 microg and 15.0 microg produced significant decreases in skin prick test sensitivity ( P = .02 and P = .002 , respectively ) .\n\nLabels: 4\n\nSample: A comparison of the efficacy of chlordiazepoxide and lorazepam was done post randomisation .\n\nLabels: 2\n\nSample: The NC performance of advanced heart failure patients supported with continuous-flow and pulsatile-flow LVADs shows stabilization or improvement during support for up to 24 months .\n\nLabels: 1\n\nSample: Completely heparin-coated CPB can safely be performed in combination with reduced systemic heparinization .\n\nLabels: 1\n\nSample: Of 143 men evaluated for the study , 118 were randomised either to start PFME preoperatively and continue postoperatively ( group A ; n = 59 ) or to start postoperative PFME ( group B ; n = 59 ) .\n\nLabels: 1\n\nSample: The planning CT scans of 47 patients prospectively enrolled and treated with IMRT arm of a phase 2 trial ( NCT00193804 ) contoured for pelvic bone marrow in 2 sets ; whole bone ( WB ) , and freehand ( FH ) inner cavity of bone .\n\nLabels: 2\n\nSample: Nasopharyngeal carcinoma ( NPC ) is well known for its invasiveness and erosion of the base of the skull is not uncommon .\n\nLabels: 3\n\nSample: Thus , GEE is not an appropriate choice for this analysis .\n\nLabels: 4\n\nSample: Notably , the impact of xenon anaesthesia did not differ significantly from sevoflurane anaesthesia with regard to leucocyte function .\n\nLabels: 1\n\nSample: After achieving a sedation and reactivity score of 3-4 , the patients were placed lateral in knee chest position and lumbar puncture performed and test drug administered .\n\nLabels: 2\n\nSample: Exercise did not influence the maximum insulin concentration ( Cmax ) , while the time to Cmax was 22 min earlier for EX30 ( P = 0.04 ) .\n\nLabels: 4\n\nSample: A single daily 20 mg dose significantly decreases 24-h intragastric acidity .\n\nLabels: 0\n\nSample: Tesaglitazar may have the potential to prevent vascular complications and delay progression to diabetes in these patients .\n\nLabels: 1\n\nSample: Randomized controlled trial , in the French-speaking part of Switzerland , September 20 , 1998 , to December 31 , 1999 .\n\nLabels: 2\n\nSample: A lower rate of cardiovascular events was observed with roflumilast than with placebo in patients with COPD , indicating the lack of a cardiovascular safety signal when treating patients with COPD .\n\nLabels: 1\n\nSample: Average pain on the Brief Pain Inventory ( BPI ) was 4.7 at baseline , 4.4 after the 2-week placebo run-in , and 3.3 at 12 weeks ( 25 % decrease , P = 0.03 ) .\n\nLabels: 4\n\nSample: Several pharmacological agents that act as antagonists to the glutamate receptor have shown promise in limiting this progression .\n\nLabels: 3\n\nSample: The physiotherapy technique used was kinesiotherapy .\n\nLabels: 2\n\nSample: The water exercise session comprised a warm-up on land , activities of daily living ( ADL ) exercises , stretching , strength training , and relaxation in water .\n\nLabels: 2\n\nSample: All reported thrombotic CV events occurring on-treatment or within 14 days after study drug discontinuation were adjudicated by an independent panel of clinical experts blinded to treatment assignment .\n\nLabels: 2\n\nSample: There was no significant difference between the median pain scores of patients treated at the LI4 site and the sham site ( P = 0.87 ) .\n\nLabels: 4\n\nSample: Infants in both groups responded differently to mother 's milk odour ( either their own or another mother 's milk ) compared to the other stimuli on days 1 and 4 .\n\nLabels: 4\n\nSample: The marked acceleration of small bowel transit also seen with inert plastic particles may be due to increased upper gut secretions after stimulation of enteric nerves .\n\nLabels: 1\n\nSample: For the chlorhexidine group , positive skin culture rates remained significantly lower than the baseline rates for 24 hours to 3 days , whereas for the placebo group , beyond the first 2-hour follow-up , these values were not lower than baseline in any of the 3 sites .\n\nLabels: 4\n\nSample: Halitosis may be a problem in some healthy children , but it does not correlate well with mothers ' breath odor or common oral parameters .\n\nLabels: 1\n\nSample: The H ( 2 ) O ( 2 ) concentration decreased significantly after the first treatment period in both sequence 1 and 2 ( p < 0.05 , p = 0.01 , respectively ) .\n\nLabels: 4\n\nSample: Fifty patients were randomized into the control group and the treatment group equally .\n\nLabels: 2\n\nSample: The anterior insula and the frontal operculum are regarded as the primary taste cortex .\n\nLabels: 1\n\nSample: The aim of this study was to examine strategies carers use to cope with the burden of caring for a young person with FEP .\n\nLabels: 0\n\nSample: Specific IgE ( D.pt .\n\nLabels: 4\n\nSample: Among patients with symptomatic femoropopliteal peripheral artery disease , percutaneous transluminal angioplasty with a paclitaxel-coated balloon resulted in a rate of primary patency at 12 months that was higher than the rate with angioplasty with a standard balloon .\n\nLabels: 1\n\nSample: After 24 h in water , the specimens were thermocycled , and the bond strengths were measured in shear .\n\nLabels: 2\n\nSample: The reduction in body mass index and percent excess weight loss ( 66 % ) were similar in both groups .\n\nLabels: 4\n\nSample: Tools to predict death or spontaneous survival are necessary to inform liver transplantation ( LTx ) decisions in pediatric acute liver failure ( PALF ) , but such tools are not available .\n\nLabels: 0\n\nSample: Although improvement was maintained in both groups , mitral-valve areas were greater in the patients in the balloon-valvuloplasty group at three years ( 2.4 + / - 0.6 cm2 , vs. 1.8 + / - 0.4 cm2 in the surgery group , P < 0.001 ) .\n\nLabels: 4\n\nSample: Each participant met monthly with a dietitian for an average of 26 months .\n\nLabels: 2\n<Assistant>Sure I will remember them.", "[Dialogue between User and Assistant on 2024-01-02 00:00]\n<User>Here are some annotated classification examples:\n\nSample: Twenty-two subjects completed the study ( 1 1 per group ) .\n\nLabels: 4\n\nSample: After a mean of 7.9 years ( standard deviation = 1.8 years ) of follow-up , 61 women in the hormone therapy group were diagnosed with lung cancer compared with 54 in the placebo group ( incidence of lung cancer per year = 0.15 % vs 0.13 % , respectively ; HR of incidence = 1.17 , 95 % CI = 0.81 to 1.69 , P = .39 ) .\n\nLabels: 4\n\nSample: Subjects with COPD exacerbations were entered into a randomized biomarker-directed double-blind corticosteroid versus standard therapy study .\n\nLabels: 2\n\nSample: Using HLM , FCBT was associated with significantly greater change in OCD severity and child-reported functional impairment than PRT and marginally greater change in parent-reported accommodation of symptoms .\n\nLabels: 4\n\nSample: The incidence of PDPH relevant to the gauges of spinal needle used was not statistically different in C/S females .\n\nLabels: 4\n\nSample: The sensitivity , specificity , and accuracy of the standard management group were 100 % , 79 % , and 89 % , respectively .\n\nLabels: 4\n\nSample: Milk production and serum prolactin were measured before and during the trial , and domperidone concentration in milk was measured during drug treatment .\n\nLabels: 2\n\nSample: Venous blood samples were taken at 0 , 30 , 60 , 120 , 240 and 360 min after the administration of misoprostol .\n\nLabels: 2\n\nSample: In conclusion , the frequency of OI is higher in women than in men and is not modified by midodrine at the dose used .\n\nLabels: 1\n\nSample: Peak COMT inhibition was similar between active treatments , but extent of COMT inhibition was more sustained with 75 and 150 mg nebicapone than with 200 mg entacapone .\n\nLabels: 4\n\nSample: Inhaled mannitol is an osmotic agent that increases the water content of the airway surface liquid , and improves the clearance of mucus with the potential to improve lung function and respiratory health .\n\nLabels: 0\n\nSample: There were more women in group II ; 41 in group I and 59 in group II , P = 0.028 .\n\nLabels: 4\n\nSample: The algorithms used to address hypercalcemia and hypercalciuria in the PaTH trial proved effective in safely resolving clinical episodes of increased urinary or serum calcium and might therefore be helpful to clinicians caring for patients on PTH .\n\nLabels: 1\n\nSample: Correct classification of chronic heart failure ( CHF ) patients by dual evidence of congestion and adequate perfusion is the primary clinical focus for management .\n\nLabels: 0\n\nSample: Patients with hypertension of 2nd degree ( n = 55 , age 35-50 years ) were divided into 2 groups with similar age , sex , duration of hypertension , and office BP level .\n\nLabels: 2\n\nSample: The therapeutic effect of the distinctive medicine cup is better than the water cup group , and the water cup group is better than the empty cup group .\n\nLabels: 1\n\nSample: Intervention pharmacists were more likely than the control pharmacists to initiate conversation on dispensing a repeat prescription and to discuss extended support .\n\nLabels: 4\n\nSample: The incidence of PROM was recorded for each group as an indicator of the protective effect of vitamin C supplementation .\n\nLabels: 2\n\nSample: Pain , motor strength , and side effects were recorded for 24 h. Venous blood was collected from 18 children to determine the plasma concentrations of levobupivacaine and/or fentanyl before and 2 , 4 , 8 , 16 , 24 , and 26 or 30 h after the start of the epidural infusion .\n\nLabels: 2\n\nSample: Number of circulating EPC , EPC-outgrowth , intima media thickness , skin microvascular function and HbA1c were documented at baseline and/or after 4 weeks and 4 months .\n\nLabels: 2\n\nSample: NNS was recommended as a beneficial intervention for premature infants during intermittent nasogastric tube feeding .\n\nLabels: 1\n\nSample: There was a significant difference in follicle count among the 3 groups ( P = .005 ) .\n\nLabels: 4\n\nSample: Activated protein C ( APC ) resistance not related to the factor V Leiden mutation is a risk factor for venous thrombosis .\n\nLabels: 3\n\nSample: Results suggest that an interactive computer-based information program for cardiac catheterization may be more effective in improving patient understanding than conventional written consent information .\n\nLabels: 1\n\nSample: The most frequent cause ( 69.5 % ) of unreliability was excessive fixation losses .\n\nLabels: 4\n\nSample: The results suggest that patient education should not be initiated before assessing the patient 's cultural and social background .\n\nLabels: 1\n\nSample: Maternal antibody is associated with a reduced infant response to PnCRM7 but does not interfere with immune memory .\n\nLabels: 1\n\nSample: The serum concentrations of ceftazidime obtained were analyzed taking into account the characteristics of the burns patients ( multivariate correlation ) .\n\nLabels: 2\n\nSample: This was a randomized , double-blind , placebo-controlled trial conducted at a tertiary level hospital from May 2008 to June 2009 .\n\nLabels: 2\n\nSample: Nurses were also more thorough than doctors in examining the stomach and oesophagus .\n\nLabels: 4\n\nSample: Clinical , pulmonary , and inflammatory responses to these controllers were evaluated .\n\nLabels: 2\n\nSample: Significantly fewer patients had a urine output < 30 ml/h in the first 24-h after operation ( P = 0.046 ) in group 2 .\n\nLabels: 4\n\nSample: Lung function , respiratory rate ( RR ) , heart rate ( HR ) , oxygen saturation ( SaO2 ) and clinical score ( CS ) were monitored .\n\nLabels: 2\n\nSample: Hormone therapy lowered plasma cholesterol levels ( p < 0.001 ) and low-density lipoprotein cholesterol ( Kiogest , p < 0.001 ; Trisequens , p < 0.01 ) , whereas high-density lipoprotein cholesterol levels were unchanged ( Trisequens ) or reduced ( Kliogest , p < 0.01 ) , primarily because of a decrease in the high-density lipoprotein-2 subfraction ( p < 0.05 ) .\n\nLabels: 4\n\nSample: : Twenty-four adult TBI survivors , randomized to acupuncture or control arms .\n\nLabels: 2\n\nSample: We investigated the influence of preoperative administration of a supplement rich in arginine , omega-3 fatty acids , and RNA , Impact ( Japan ) , on inflammatory and immune responses in patients undergoing major surgery for cancer .\n\nLabels: 3\n\nSample: Furthermore , 29 % of the parents were not psychologically prepared to remove the dressing and 12 % were so reluctant that the dressing was removed at the urology outpatient clinic .\n\nLabels: 4\n\nSample: So it has a higher clinical application value .\n\nLabels: 1\n\nSample: Reduction of the contrast material volume by optimised bolus administration during a breath-hold 3D MR angiography and its clinical value .\n\nLabels: 3\n\nSample: Diamorphine provided modestly improved pain relief at 60minutes , mean difference 1cm ( 95 % confidence interval [ CI ] 0.5-1 .5 ) , and over the 3hours , mean difference 0.7 cm ( 95 % CI 0.3-1 .1 ) .\n\nLabels: 4\n<Assistant>I've captured all of this valuable information.", "[Dialogue between User and Assistant on 2024-01-03 00:00]\n<User>Please memorize these classification examples and their labels:\n\nSample: Of the 2607 eligible women , 1009 were randomly assigned to screening and 1598 to usual care .\n\nLabels: 4\n\nSample: Low dose of erythromycin could improve the successful rate of feeding in critically ill patients in ICU .\n\nLabels: 1\n\nSample: Mean changes from baseline CRP at week 8 in the primary group were -0.3 and -3.1 mg/l after treatments with placebo ( n = 43 ) and ustekinumab ( n = 46 ) , respectively ( P = 0.074 ) .\n\nLabels: 4\n\nSample: Low acculturation did not present a barrier to delivery of the intervention once the participant was enrolled .\n\nLabels: 4\n\nSample: The study was designed as a longitudinal , monocentric , prospective , controlled , and randomized cross-over study and included 12 postlingually deafened adults , who were experienced cochlear implant users .\n\nLabels: 2\n\nSample: Early - and late-treatment side effects .\n\nLabels: 2\n\nSample: Major adverse cardiac events ( MACE ) ( death , myocardial infarction , coronary revascularization , rehospitalization for heart failure ) will be assessed at 4 , 12 , and 24 months and time to MACE will be estimated .\n\nLabels: 2\n\nSample: The mean daily number of hot flushes was 6.4 ( SD 5.1 ) .\n\nLabels: 4\n\nSample: We assessed 18-24-month postpartum disease progression risk among women in a randomized trial assessing efficacy and safety of prophylactic maternal ARVs .\n\nLabels: 0\n\nSample: Participants were asked to determine their procedure allocation at the end of treatment .\n\nLabels: 2\n\nSample: The primary efficacy measure was the change from baseline on the Menopause Rating Scale I ; secondary measures included changes in its subscores and safety variables .\n\nLabels: 2\n\nSample: Overall , 66 % of women had ultrasonographic evidence of a residual full-thickness defect in the external anal sphincter after primary repair .\n\nLabels: 4\n\nSample: Despite no differences at baseline , only the n3-FA group decreased fasting insulin and HOMA-IR ( p < 0.010 ) .\n\nLabels: 4\n\nSample: No major side effects were noted in either groups .\n\nLabels: 4\n\nSample: To address these barriers , evidence based interventions need to move beyond isolated efficacy trials and report outcomes related to effectiveness and implementation .\n\nLabels: 1\n\nSample: Fimasartan had a good safety profile and was well tolerated after fasted single oral doses of 20-480 mg , a fed single oral dose of 240 mg , and fasted repeated oral doses of 120 and 360 mg in healthy subjects .\n\nLabels: 1\n\nSample: A prospective randomized study .\n\nLabels: 2\n\nSample: Antihistaminic treatment of allergic asthma or cough-type asthma , including cough associated with allergic rhinocojunctivitis , has been recently reconsidered prospectively since new very potent compounds , nonsedating with anti-allergic properties , are available .\n\nLabels: 0\n\nSample: At endpoint , there was a mean decrease of 8.5 + / - 0.7 ( 31.7 % ) in the YBOCS total score compared with baseline in the fluvoxamine CR treatment group versus a mean decrease of 5.6 + / - 0.7 ( 21.2 % ) in the placebo group ( p = .001 ) .\n\nLabels: 4\n\nSample: Medians of operation times in the LNF and ONF groups were 98 min and 74 min , respectively .\n\nLabels: 4\n\nSample: Dual-energy x-ray absorptiometry ( DXA ) scans of the lumbar spine and bilateral distal femora were performed preoperatively and at least 4 weeks postoperatively .\n\nLabels: 2\n\nSample: Topical tetracaine 0.5 % with intracameral lidocaine was safe and effective in patients having phacoemulsification with IOL implantation .\n\nLabels: 1\n\nSample: Mean Kt/Vs during the study were 1.27 ( 95 % confidence interval [ CI ] , 1.19 to 1.35 ) , 1.41 ( 95 % CI , 1.32 to 1.50 ) , 1.31 ( 95 % CI , 1.22 to 1.39 ) , and 1.41 ( 95 % CI , 1.33 to 1.49 ) for patients receiving standard dialysis , 4.5 hours of hemodialysis , hemodialysis with increased dialysate flow , and hemodialysis with 2 dialyzers , respectively .\n\nLabels: 4\n\nSample: Patients were randomly assigned to study and control groups .\n\nLabels: 2\n\nSample: Daily consumption of figs did not reduce low-density lipoprotein cholesterol .\n\nLabels: 1\n\nSample: Prophylactic intrapartum saline amnioinfusion is an effective technique for the reduction of lipid peroxidation and of the incidence of operative intervention for fetal distress but has no significant effect on overall operative delivery rates .\n\nLabels: 1\n\nSample: Bristol-Myers Squibb .\n\nLabels: 0\n\nSample: PD as an intervention is acceptable to patients and has reasonable endorsement by the majority of physicians .\n\nLabels: 1\n<Assistant>Thank you for sharing. I've noted this information.", "[Dialogue between User and Assistant on 2024-01-04 00:00]\n<User>Here are some examples with classification labels to remember:\n\nSample: Randomised controlled trial with cost-effectiveness analysis .\n\nLabels: 2\n\nSample: Group GTN received 0.2 % glyceryl trinitrate , group L received 10 % lidocaine , and group D received 2 % diltiazem ointment .\n\nLabels: 2\n\nSample: Regular use of anti-fungal shampoos represents a proven therapeutic strategy to improve the most common symptoms of flakes and itch .\n\nLabels: 3\n\nSample: This is a post-hoc analysis from the Extended-ESTABLISH trial , which was designed to estimate the impact of renal insufficiency on patients with ACS after percutaneous coronary intervention over the long term .\n\nLabels: 2\n\nSample: Overall acceptance of the delivered anaesthesia was lower in the K/P group .\n\nLabels: 4\n\nSample: This study was conducted to evaluate the pharmacokinetics and tolerability of quetiapine XR administered as a single dose ( 300 mg ) and multiple doses ( 300 , 600 , and 800 mg ) in Han Chinese patients with schizophrenia .\n\nLabels: 3\n\nSample: Olopatadine 0.2 % ( instilled twice-daily ) is safe , well tolerated , superior to the vehicle , and similar to olopatadine 0.1 % in preventing ocular itching .\n\nLabels: 1\n\nSample: Eleven patients with iSCI participated in a single training session with the gait rehabilitation robot Lokomat .\n\nLabels: 2\n\nSample: Gain was always higher in patients than in controls but showed no significant association with outcome or other clinical factors .\n\nLabels: 4\n\nSample: However , cupfed infants took less volume , over more time , than bottlefed for these initial feedings .\n\nLabels: 1\n\nSample: TG at 180 min , and FFA at 180 and 240 min were higher after SCHO breakfast than after CCHO breakfast .\n\nLabels: 4\n\nSample: Therefore , we want to determine whether six-monthly monitoring of well-controlled type 2 diabetes patients in primary care leads to equivalent cardiometabolic control compared to the generally recommended three-monthly monitoring .\n\nLabels: 0\n\nSample: One in five surrogates estimated the patient 's prognosis was greater than 20 % more optimistic than the physician 's prognostication .\n\nLabels: 4\n\nSample: A high Th2/Th1 ratio ( CCL22/CXCL10 ) at birth associated with both sensitization and eczema development .\n\nLabels: 4\n\nSample: A group-randomized efficacy trial of PnCRM7 ( vaccine serotypes 4 , 6B , 9V , 14 , 18C , 19F , and 23F ) was conducted on the Navajo and White Mountain Apache reservations from April 1997 to October 2000 .\n\nLabels: 2\n\nSample: Randomisation was carried out for each centre and was stratified according to the size ( more or less than 10 cm2 ) of the ulcerated area .\n\nLabels: 2\n\nSample: The 2 dosages investigated showed equal results .\n\nLabels: 4\n\nSample: The hydroxyrisperidone AUC was lower in individuals with the COMT mutant genotype .\n\nLabels: 4\n\nSample: The motor function of the affected limb was evaluated by Fugl-Meyer scale , activity of daily living by ADL scale , and pain by VAS , and the edema degree was investigated before and after treatment .\n\nLabels: 2\n\nSample: Despite the prevalence and associated family and infant morbidity , there are no controlled clinical treatment trials regarding this topic , to the authors ' knowledge .\n\nLabels: 3\n\nSample: Endothelium-dependent vasodilation ( EDV ) and endothelium-independent vasodilation ( EIV ) were measured by use of brachial artery ultrasonography in 75 asymptomatic patients with T2DM ( 56 men ; mean age , 58.6 + / - 6.4 years ; mean duration of diabetes , 8.4 + / - 7.5 years ) who underwent adenosine MPI .\n\nLabels: 4\n\nSample: Seventeen pharmacists recruited 142 patients ( 97 completions : 49 control , 48 intervention ) .\n\nLabels: 4\n\nSample: The 5-year estimated cumulative incidence of failure for the irradiated patients was local , 13 % ; regional , 3 % ; and distant , 13 % ; with no differences between HFRT and CFRT .\n\nLabels: 4\n\nSample: To compare GH responses to repeated bout of three different GH-releasing stimuli .\n\nLabels: 3\n\nSample: Patients recorded nausea and emesis in a diary .\n\nLabels: 2\n\nSample: Correlations and logistic regression analyses show the expected relationship among the various global and specific indicators .\n\nLabels: 4\n\nSample: Despite the progressive increase in the number of antidepressants , many patients with major depressive disorder continue to be symptomatic .\n\nLabels: 3\n\nSample: Accrual of disability during the RCT ( R ( 2 ) = 0.12 ; p < 0.0001 ) and annualised relapse rates during the trial correlated with physical outcome ( R ( 2 ) = 0.12 ; p < 0.0001 ) but not with cognition .\n\nLabels: 4\n\nSample: Stent restenosis occurred for one patient with the Wallflex stent .\n\nLabels: 4\n\nSample: To observe the clinical effect of Shengxueling Granule ( SXLG ) in treating idiopathic thrombocytopenic purpura ( ITP ) , and to study its possible mechanism .\n\nLabels: 3\n\nSample: For continuous infraclavicular nerve blocks , local anesthetic concentration and volume influence perineural infusion effects in addition to the total mass of local anesthetic administered .\n\nLabels: 1\n\nSample: Medication satisfaction at both time points was significantly associated in multiple regression analysis with improvement on 3 Positive and Negative Syndrome Scale ( PANSS ) factor scores ( positive symptoms p < .01 ; uncontrolled hostility/excitement , p < .0005 ; anxiety/depression , p < .04 ) and treatment with risperidone ( p < .03 ) ; at day 14 , significant association was also found with older age ( p = .01 ) .\n\nLabels: 4\n\nSample: The protective efficacy of consultation was 58 % ( 95 % CI , 3 % to 82 % ) .\n\nLabels: 4\n\nSample: Qualitative results were in good agreement with quantitative results .\n\nLabels: 4\n\nSample: The size of corneal flap created with 70 side-cut angle was more accurate compared with 115 side-cut angle .\n\nLabels: 1\n\nSample: ( 4 ) Long-term survival is closely related to treatment mode .\n\nLabels: 4\n\nSample: Malondialdehyde ( MDA ) , glutathione peroxidase ( GSH-Px ) , nitric oxide ( NO ) levels and neutrophil percentage were determined .\n\nLabels: 2\n\nSample: It was also increased after hemodilution in HG ( P < 0.042 ) .\n\nLabels: 4\n\nSample: No late complications or deaths occurred in the surgery groups .\n\nLabels: 4\n\nSample: The patients were randomly assigned to one of the two different treatment regimes : DOXY ( exclusively subgingival application of a 14 % doxycycline gel ) or SRP ( scaling and root planing with a sonic scaler ) .\n\nLabels: 2\n\nSample: Before exercise , standing heart rate and blood pressure were measured under each BWS condition .\n\nLabels: 2\n\nSample: Thirty-six patients were randomized , 19 to the UAS and 17 to the conventional group .\n\nLabels: 4\n\nSample: The study provided evidence to support that structured lipids may represent a next generation of IV fat emulsions that may be clinically advantageous compared with conventional LCT emulsions in certain clinical conditions .\n\nLabels: 1\n\nSample: Hyperandrogenism , lipid profiles , hirsutism scores , menstrual irregularity , insulin sensitivity and tumour necrosis factor - ( TNF - ) levels were measured at baseline and after the treatment period .\n\nLabels: 2\n\nSample: The increase in the forearm blood flow after isosorbide dinitrate was similar before and after 12 weeks of follow-up in both groups .\n\nLabels: 4\n\nSample: Jerseys had higher blood concentrations of Se than Holsteins 3 to 4 weeks prior to parturition and at parturition .\n\nLabels: 4\n<Assistant>I've successfully recorded all of this data.", "[Dialogue between User and Assistant on 2024-01-05 00:00]\n<User>These examples show different classes - please note the labels:\n\nSample: We evaluated patterns of tumor progression in patients with recurrent glioblastoma who were treated with bevacizumab ( BEV ) alone or in combination with irinotecan ( CPT-11 ) while participating in the BRAIN study .\n\nLabels: 3\n\nSample: The findings were more robust in patients receiving usual care for depression than in patients receiving enhanced care .\n\nLabels: 4\n\nSample: Positive correlations between response to rFVIII and body surface area ( r = 0.734 , p = 0.015 ) , body weight ( r = 0.762 , p = 0.01 ) , and plasma volume ( r = 0.659 , p = 0.03 ) were observed .\n\nLabels: 4\n\nSample: In a double-blind , placebo-controlled cross-over design , 15 patients were treated with a 3-week fixed titration scheme of modafinil and placebo .\n\nLabels: 2\n\nSample: However , if the OVD is removed , postoperative IOP spikes above 21 mm Hg appear related more to patient factors ( eg , predisposition in glaucoma patients ) and surgically induced trauma than to the specific long-chain non-cross-linked hyaluronan OVD used .\n\nLabels: 1\n\nSample: Responders ( i.e. , no MDD and 17-item Hamilton Rating Scale for Depression < or = 12 ) were stratified into higher and lower risk groups based on stability of remission during the last 6 weeks of CT. .\n\nLabels: 2\n\nSample: Patients with high-risk bleeding peptic ulcers after successful endoscopic therapy were randomly assigned as oral lansoprazole or intravenous esomeprazole group .\n\nLabels: 2\n\nSample: This study involved ambulatory patients attending a local hospital and university center .\n\nLabels: 2\n\nSample: Students were tested over time in grades 7 , 8 and 9 .\n\nLabels: 2\n\nSample: The mean pupil sizes at 40 min were 6.6 + / -0.8 and 6.0 + / -0.9 mm in the mixture and alternate drug groups respectively ( P = 0.050 , t-test ) .\n\nLabels: 4\n\nSample: There was no statistically significant difference in extubation times or VAS scores between the 2 groups .\n\nLabels: 4\n\nSample: However , other indicators of bipolar diathesis including recent maniclike symptoms and family history of bipolar disorder as well as summary measures of bipolar spectrum features were not associated with treatment resistance .\n\nLabels: 4\n\nSample: The groups did differ with respect to total operation time ( 73 min in the laparoscopy group vs. 88 min in the laparotomy group ) , hospital stay ( 2.2 days vs. 5.4 days ) and convalescence period ( 11 days vs. 24 days ) .\n\nLabels: 4\n\nSample: This study evaluates the baseline visual field test characteristics ( visual field status , reliability properties , etc. ) of patients who underwent eligibility visual field testing for entry to the OHTS .\n\nLabels: 3\n\nSample: There was no difference in the percentage of children with low fiber intake living in the United States ( 70 % ) and Italy ( 71 % ) .\n\nLabels: 4\n\nSample: Shoulder tendinitis and subacromial bursitis are acute , painful inflammatory musculoskeletal conditions that may recur as a result of overuse .\n\nLabels: 3\n\nSample: Type 2 diabetic patients with microalbuminuria have impaired endothelium-dependent and - independent vasodilation .\n\nLabels: 1\n\nSample: After misoprostol treatment , patients reported bleeding or spotting every day for the 14 days observed .\n\nLabels: 4\n\nSample: There were no statistically significant differences between the two mouthrinses in any of these measurements .\n\nLabels: 4\n\nSample: Concerns exist about deleterious renal effects of low-carbohydrate high-protein weight loss diets .\n\nLabels: 3\n\nSample: Angiotensin II receptor blockers ( ARBs ) have been reported to possibly improve coronary endothelial function and coronary microvascular function .\n\nLabels: 3\n\nSample: In glove study 2 , surgeons retaining outer gloves 1 hour into the case had a subsequent positive glove contamination rate of 23 % compared with 13 % among surgeons exchanging their original outer glove [ odds ratio ( 95 % confidence interval ) : 1.97 ( 1.02-3 .80 ) ; P = 0.0419 ] .\n\nLabels: 4\n\nSample: The main stratifying variable was maternal schooling dichotomized as < 6years and 6years .\n\nLabels: 2\n\nSample: Of the 106 dyads enrolled in the study , 80 children and 85 parents provided useable actigraphy data .\n\nLabels: 4\n\nSample: The preparations were filled with composite resin ( 1 ) , with composite resin using the incremental technique ( 2 ) , an experimental glass-fiber-reinforced ( 3 ) and polyester-reinforced ( 4 ) composite resin , a direct composite inlay ( 5 ) , a ceramic insert ( 6 ) , a Cerafil inlay ( 7 ) , and with an experimental direct filling using Dyract AP compomer ( 8 ) .\n\nLabels: 2\n<Assistant>Thanks for sharing. I've committed this to memory.", "[Dialogue between User and Assistant on 2024-01-06 00:00]\n<User>I'm providing classification data with labels for your reference:\n\nSample: The results of the Dix-Hallpike maneuver were negative for positional nystagmus in 16 ( 67 % ) of 24 patients in the CRP group and in 10 ( 38 % ) of 26 patients in the sham group ( P = .046 ) .\n\nLabels: 4\n\nSample: The secondary objective was the assessment of the tolerance of propafenone versus amiodarone .\n\nLabels: 3\n\nSample: In control group ( n = 3,321 ) mothers receive traditional management .\n\nLabels: 2\n\nSample: Early oral feeding ( EOF ) following colorectal surgery can accelerate patient recovery and shorten hospital stay .\n\nLabels: 0\n\nSample: The imaging protocols varied widely among the institutions .\n\nLabels: 4\n\nSample: Central serotonin dysfunction is thought to be involved in the etiology of major depression .\n\nLabels: 0\n\nSample: Lumbar spine appears to be affected to a higher degree .\n\nLabels: 1\n\nSample: The expression of VCAM-1 ( IL-4 / Th2-dependent ) and ICAM-1 ( INF-gamma/IL -1 ) on dermal vessels was compared in six patients with AD and six patients with ACD .\n\nLabels: 3\n\nSample: We hypothesized that greater carotid intima-media thickness and the presence of electrocardiographic left ventricular hypertrophy would be independently associated with increased ICH incidence .\n\nLabels: 3\n\nSample: The therapeutic relevance of the P2X7 receptor remains to be tested in patients .\n\nLabels: 1\n\nSample: All patients with histopathologically proven Stages IB-IVA cervical carcinoma , treated at our institution with PDR intracavitary BT between April 1996 and November 2007 , were included in this retrospective analysis .\n\nLabels: 2\n\nSample: There was no significant difference between the airway leak pressures of the two devices [ median ( IQR ) leak pressures 25 ( 22-30 ) vs 22 ( 20-28 ) cm H ( 2 ) O for the i-gel and LMA-U , respectively ; P = 0.083 , 95 % CI of the mean difference -0.32 to 4.88 cm H ( 2 ) O ] .\n\nLabels: 4\n\nSample: To compare the efficacy and safety of statin ( HMG-CoA reductase inhibitor ) monotherapy versus ezetimibe 10mg plus statin in older and younger adults with primary hypercholesterolaemia .\n\nLabels: 3\n\nSample: Patient delays in seeking treatment for stroke and delays within the Emergency Department ( ED ) are major factors in the lack of use of thrombolytic therapy for stroke .\n\nLabels: 3\n\nSample: This study evaluates the cost-effectiveness of this approach .\n\nLabels: 0\n\nSample: In the diode laser group , the average baseline intraocular pressure was 21.6 + / - 2.0 mm Hg before trabeculoplasty and 19.6 + / - 2.1 mm Hg ( or a 7.7 % + / - 11.5 % mean pressure reduction ) at 1 month , 19.3 + / - 2.6 mm Hg ( or a 6.9 % + / - 13.5 % mean reduction ) at 2 months , and 19.0 + / - 3.3 mm Hg ( or a 2.4 % + / - 16.9 % mean reduction ) at 3 months postoperatively .\n\nLabels: 4\n\nSample: Application of class I and II compressive hosiery resulted in LEP/TP decrease by 17 % ( 95 % confidence interval , 0.07 to 0.26 ) and 14 % ( 95 % confidence interval , 0.04 to 0.21 ) , respectively , suggestive of dermal edema reduction .\n\nLabels: 4\n\nSample: In parallel a significant decrease in carriage rate of antibiotic-resistant pneumococci was observed .\n\nLabels: 4\n\nSample: Stroke service based on treatment in a stroke unit combined with early supported discharge appears to improve the long-term clinical outcome compared with ordinary stroke unit care .\n\nLabels: 1\n\nSample: Outcomes were sternal separation measured by ultrasound in mm , pain during the performance of nine everyday tasks measured on a 100-mm visual analogue scale , and the quality and control of the performance of two tasks scored on a 100-mm visual analogue scale .\n\nLabels: 2\n\nSample: The conventional respiratory therapy was held in both groups , twice a day .\n\nLabels: 2\n\nSample: No significant difference was found between the intervention and control groups concerning overall psychological health .\n\nLabels: 4\n\nSample: Factors predicting non-enrollment were analyzed using multivariate logistic regression test .\n\nLabels: 2\n\nSample: There is no evidence of any benefit derived from the practice of applying suction to EBUS-guided biopsies .\n\nLabels: 1\n\nSample: No difference was observed between groups in mean scores on the General Health Questionnaire or the Bradford Somatic Inventory , or in number of complaints or patient-initiated consultations at 3 months .\n\nLabels: 4\n\nSample: Children ill at other times during the study period were , if possible , seen and assessed by the study team .\n\nLabels: 2\n\nSample: Of the 67 women , 32 ( 47 % ) completed the study ; the proportion completing was the same in both groups .\n\nLabels: 4\n\nSample: Horses were fasted overnight prior to receiving one of 4 ACE inhibitors intragastrically , administered at one of 2 dosages , using a randomized Latin square design ( benazepril : 0.5 and 0.25 mg/kg ; ramipril : 0.3 and 0.1 mg/kg ; quinapril : 0.25 and 0.125 mg/kg ; perindopril : 0.1 and 0.05 mg/kg ) .\n\nLabels: 2\n<Assistant>I've processed this information and will remember it.", "[Dialogue between User and Assistant on 2024-01-07 00:00]\n<User>Please observe these classification examples and their associated labels:\n\nSample: Patients were randomly assigned to two groups : the ceftriaxone group ( R-group , n = 95 ) and sulperazon group ( S-group , n = 95 ) .\n\nLabels: 2\n\nSample: Teeth were randomly assigned ( 10 teeth per group ) to three groups : ( 1 ) smear layer removed , ( 2 ) smear layer present , and ( 3 ) negative control .\n\nLabels: 2\n\nSample: An incisor with a circular shoulder preparation ( 1 mm ) was inserted in a primary mold .\n\nLabels: 2\n\nSample: Primary endpoint of the study is the absence of documented persistent atrial tachyarrhythmias relapse during the first 24 months after the blanking period .\n\nLabels: 4\n\nSample: Subjects consumed in random order three equi-carbohydrate meals based on a popular puffed rice cereal containing three levels of sucrose ( 0 , 21 and 43 g ) .\n\nLabels: 2\n\nSample: The postmeal glucose increase was 22mg/dL for meal 1 and 31mg/dL for meal 2 .\n\nLabels: 4\n\nSample: This technique is recommended for VATS surgery , especially if day-case procedures are being contemplated .\n\nLabels: 1\n\nSample: The main substudy analysis end point was death or myocardial infarction ( MI ) rates at the 6-month follow-up .\n\nLabels: 4\n\nSample: Behavioural and lifestyle counselling provided by specialized nurses with training in managing incontinence reduces incontinent events and incontinence pad use .\n\nLabels: 1\n\nSample: isrctn.org Identifier : ISRCTN60825437 .\n\nLabels: 0\n\nSample: Zero-balanced modified hemodiafiltration without addition of vacuum suction is effective in improving the elimination of bivalirudin after CPB and reducing the postoperative blood loss .\n\nLabels: 1\n\nSample: Nearly 40 % of fully adherent subjects ( receiving > 75 % of either psychotherapy or pharmacotherapy ) were in remission at follow-up ( odds ratio , 3.6 ; P = .04 ) .\n\nLabels: 4\n\nSample: One hundred ten patients were assessed for eligibility for the study ; 14 patients were not recruited because they resided outside the country ( 3 ) , refused participation ( 8 ) , or were not consented before independent ambulation ( 3 ) .\n\nLabels: 2\n\nSample: Additionally , patients in the intervention group participated in an 11-month community-based exercise programme led by physiotherapists .\n\nLabels: 2\n\nSample: It is inexpensive and its yield is relatively high for predicting liver and bone metastases .\n\nLabels: 1\n\nSample: These data encourage further controlled trials with more patients and longer periods of synthetic L-T ( 3 ) administration .\n\nLabels: 1\n\nSample: Adding inulin to pasta could be a preventive strategy for delaying the onset of atherosclerosis .\n\nLabels: 0\n\nSample: The 607 patients in the Collaborative Initial Glaucoma Treatment Study received standardized examinations of visual field at enrollment .\n\nLabels: 2\n\nSample: Additional imaging was necessary in 11 % of patients in the MRA group compared to 10 % in the DSA group ( p = 0.5 ) .\n\nLabels: 4\n\nSample: Although the number of patients and length of follow-up in this study was limited , a better visual outcome and diminished retreatment rate were observed in patients assigned to twofold illumination PDT scheme in comparison to those submitted to standard PDT regimen .\n\nLabels: 1\n\nSample: We also investigated if higher earnings and employment improved mortality of the participants .\n\nLabels: 3\n\nSample: Outcome measures were : borderline and general psychiatric symptomatology , suicide attempts , quality of life and use of care services .\n\nLabels: 2\n\nSample: Sick leave days ( primary outcome ) were self-reported via postal questionnaire every 4 weeks during the first 6 months post-surgery and at 12 months .\n\nLabels: 2\n\nSample: The most significant side effect of latanoprost was increased pigmentation of the iris which was observed in 15 patients ( 10.1 % ) .\n\nLabels: 4\n\nSample: The LT receptor antagonist was considered to be the most effective .\n\nLabels: 1\n\nSample: At T3 , significant reductions were observed in rhinitis ( 44 % in IT3 and 50 % in IT5 ; P < .001 ) , asthma ( 80.9 % in IT3 and 70.9 % in IT5 ; P < .001 ) scores , VAS ( P < .001 in both ) , RQLQ ( P < .001 in both ) and AQLQ ( P < .001 in both ) .\n\nLabels: 4\n\nSample: Blood conservation devices can be used as part of a comprehensive blood conservation program in the critical care setting without undue concern for exacerbating infectious processes .\n\nLabels: 1\n\nSample: NCT01484652 .\n\nLabels: 0\n\nSample: Safety and tolerability were monitored .\n\nLabels: 2\n\nSample: Arterial plus cardioplegic LF significantly reduced proinflammatory cytokine release after cardiopulmonary bypass , thus ameliorating postoperative indexes of lung function and overall respiratory outcome .\n\nLabels: 1\n\nSample: One-hundred and forty-five haemodialysis patients with the same weekly EPO dose s.c. for 3 months and a stable Hb ( maximum fluctuation of 1 mmol/l ) were randomized in a crossover study to group A ( 4 months i.v. then 4 months s.c. EPO ) or group B ( 4 months s.c. then 4 months i.v. EPO , with unchanged EPO dose ) .\n\nLabels: 2\n\nSample: The rates of graft-related complications and reinterventions were higher with endovascular repair , and new complications occurred up to 8 years after randomization , contributing to higher overall costs .\n\nLabels: 4\n\nSample: To collect the information necessary to design the methods and outcome variables for a larger trial of scheduled deep brain stimulation ( DBS ) for Tourette syndrome .\n\nLabels: 3\n\nSample: A total of 16 participants ( 7 men and 9 women ) performed a sustained-attention-to-response task before and after a 7.1-magnitude earthquake .\n\nLabels: 2\n\nSample: Ischemic heart disease is a leading worldwide cause of death .\n\nLabels: 3\n\nSample: Mean age was 47 years and duration of diabetes was 26 years .\n\nLabels: 4\n\nSample: In this relatively small group of overweight diabetics with low HDLCH rosuvastatin and fenofibrate exerted expected effects on lipid profile .\n\nLabels: 1\n\nSample: Pain intensity , morphine consumption , side effects , overall sedation and satisfaction scores were recorded and plasma cortisol was tested .\n\nLabels: 2\n\nSample: The difference between the usage of ACE inhibitors and spironolactone is significant in patients with systolic dysfunction equally qualifying for both medications .\n\nLabels: 1\n\nSample: Among current smokers , clopidogrel also reduced myocardial infarction , vascular death , and death from any cause compared with aspirin .\n\nLabels: 4\n\nSample: Rescuers ' physiologic signs were recorded before and after each session , and heart rate ( HR ) data were tracked continuously .\n\nLabels: 2\n\nSample: The plasma concentration of carboxyhemoglobin ( HbCO , as index for CO poisoning severity ) , Mb , CK-MB , and cTnI in these patients were further examined 24 hours , 72 hours and 1 week after the treatment , for difference between the two groups , and the correlation between the serum level of HbCO and the myocardial injury markers .\n\nLabels: 2\n\nSample: The clinicians who achieved the required quality of TA post assessments were likely to be able to carry out TA in an RCT with high fidelity .\n\nLabels: 4\n\nSample: Leg wound complications were significantly ( p < or = 0.02 ) reduced in group A ( 4 % [ 2 of 51 ] versus 19 % [ 11 of 58 ] ) .\n\nLabels: 4\n\nSample: Topical 2 % diclofenac in PLO appears to provide effective short-term reduction in elbow pain and wrist extensor weakness associated with chronic lateral epicondylitis .\n\nLabels: 1\n<Assistant>I understand. I'll keep this in mind.", "[Dialogue between User and Assistant on 2024-01-08 00:00]\n<User>Study these classification examples and pay attention to the categories:\n\nSample: Changes in drug delivery rate may result in clinically important changes in drug effects .\n\nLabels: 3\n\nSample: Compared with usual care , 2 different inexpensive interventions resulted in significant increases in appropriate management of OP after hip fracture .\n\nLabels: 1\n\nSample: Tolerability assessments were performed throughout the study .\n\nLabels: 2\n\nSample: A pragmatic and generalisable randomised controlled trial was undertaken to assess the use of the functional cardiac tests : angiography ( controls ) ; single photon emission computed tomography ( SPECT ) ; magnetic resonance imaging ( MRI ) ; stress echocardiography .\n\nLabels: 2\n\nSample: Of 338 patients with out-of-hospital cardiac arrest , 115 had a cardiac etiology , presented with ventricular fibrillation , and were shocked with an AED .\n\nLabels: 4\n\nSample: Ketorolac may be effective when administered by PCA device , and has a clear morphine-sparing effect .\n\nLabels: 1\n\nSample: The use of RFA that includes cost and time does not offer any clear added benefit on the midterm pain management of such patients .\n\nLabels: 1\n\nSample: There were no injuries to the frontal nerve in any of the dissections .\n\nLabels: 4\n\nSample: FFIS also improved pre-dose FEV1 beyond that of IPR-ALB in subjects who were older ( 65 years ) , male , and with both moderate and severe/very severe COPD .\n\nLabels: 4\n\nSample: IOP was assessed pre-dose and 2 hours after morning dosing at weeks 2 , 6 , and 12 .\n\nLabels: 2\n\nSample: However , aminophylline did not affect ST segment elevation .\n\nLabels: 4\n\nSample: Eosinophil cationic protein levels were evaluated by means of nasal lavage .\n\nLabels: 2\n\nSample: While STEALTH liposome encapsulation of cisplatin allowed the safe administration of five times the maximally tolerated dose of free cisplatin to dogs without concurrent hydration protocols , this did not translate into significantly prolonged DFS or OS .\n\nLabels: 1\n\nSample: A secondary data analysis from vaginal deliveries in a hospital-based cohort study from 24 maternity hospitals in South America .\n\nLabels: 2\n\nSample: Compared to the mailed information group , SS in the home-based group demonstrated significantly improved self-reported health and cognitive function ; CG demonstrated significantly improved self-reported health and coping strategies .\n\nLabels: 4\n\nSample: Both interventions increased vaccination rates in all age/sex groups .\n\nLabels: 4\n\nSample: Results support the usefulness of the DISC in further clinical and epidemiologic research ; however , closely spaced or repeated DISC interviews may result in significant diagnostic attenuation on retest .\n\nLabels: 1\n\nSample: Oxygen extraction ( arterial-coronary sinus O2 content ) was higher early after crystalloid cardioplegia ( 3.02 + / - 0.13 vs 2.35 + / - 0.22 mmol/L , p = 0.01 ) , possibly reflecting a difference in oxygen debt .\n\nLabels: 4\n\nSample: Intrinsic subtypes and the DBCG-RT profile was determined from microarray analysis based on fresh frozen tissue from 191 patients included in the Danish Breast Cancer Cooperative Group ( DBCG ) 82bc trial .\n\nLabels: 2\n\nSample: Similar reductions in triglycerides were observed across the three groups , and none of the treatments produced a significant change in HDL-C .\n\nLabels: 4\n\nSample: Infants were randomized to early iNO or to simulated initiation of iNO ( control ) .\n\nLabels: 2\n\nSample: Following arthroscopic acromioplasty , real acupuncture compared to sham acupuncture offered significantly greater improvement via : ( 1 ) lower pain level , ( 2 ) less analgesic use , ( 3 ) range of motion , and ( 4 ) patient satisfaction .\n\nLabels: 1\n\nSample: Participants and investigators were aware of assignment to fulvestrant or exemestane , but not of assignment to anastrozole or placebo .\n\nLabels: 2\n\nSample: Men had fewer coryza episodes ( 23 lysine , 39 placebo ; OR : 0.60 ; 95 % CI : 0.36 , 1.01 ; P = 0.05 ) , total number of days ill ( lysine : 130 ; placebo : 266 ; OR : 0.51 ; 95 % CI : 0.28 , 0.93 ; P = 0.03 ) , and mean days ill per person per week ( lysine : 0.21 0.23 ; placebo : 0.41 0.35 ; P = 0.04 ) .\n\nLabels: 4\n\nSample: Indirect markers of tissue hypoxia ( eg , expression of hypoxia-inducible factor-1 [ HIF-1 ] , vessel diameter , and number of vessels ) were also assessed .\n\nLabels: 2\n\nSample: It is important to know how the strategies used in performing the respective tasks vary with payoffs .\n\nLabels: 0\n\nSample: Home-based exercise is a feasible nonpharmacological intervention with the potential to alleviate postpartum depressive symptoms , especially in women with higher initial depressed mood scores as measured by the EPDS .\n\nLabels: 1\n\nSample: Outcomes were assessed using the 10-item Apathy Evaluation Scale and the Cornell Scale for Depression in Dementia .\n\nLabels: 2\n\nSample: Posttrial use of aspirin was assessed at the 7-year follow-up among 18 496 participants with no previous reported CVD .\n\nLabels: 2\n\nSample: At day 28 , PCR-uncorrected ACPR was 92 % in the DHA/PQP and 74 % in the AL arm ( OR : 4.05 ; 95 % CI : 1.89-8 .74 ; p < 0.001 ) .\n\nLabels: 4\n\nSample: Between March 1991 and April 1993 , 125 patients with metastatic RCC were randomized to receive IL-2 by intravenous bolus every 8 hours at either 720,000 IU/kg ( high-dose ) or 72,000 IU/kg ( low-dose ) to the maximum-tolerated number of doses ( or a maximum of 15 doses ) .\n\nLabels: 2\n\nSample: Verbal fluency decreased after both left-sided thalamotomy and thalamic stimulation .\n\nLabels: 1\n\nSample: The secondary outcomes were active wrist extension , flexion , radial deviation , and ulnar deviation , and the performance and satisfaction items of the Canadian Occupational Performance Measure ( COPM ) .\n\nLabels: 2\n\nSample: Rising costs and lowered reimbursements make value essential if laparoscopic cholecystectomy ( LC ) is to be offered to patients without condemning providers to financial loss .\n\nLabels: 3\n\nSample: The study also assesses the reduction in zinc and the omission of - carotene from original AREDS formulation .\n\nLabels: 3\n\nSample: The outcomes were considered satisfactory in the majority of cases by both the patient ( p = 0.78 ) and the physician ( p = 0.58 ) .\n\nLabels: 4\n\nSample: However , it benefited embryo quality , demonstrating the potential negative impact of high O2 tension on the in vitro embryo development .\n\nLabels: 1\n\nSample: According to a Fleming 2-stage phase 2 design , monotherapy was considered to be efficacious if at least 59 patients achieved VL < 200 copies/mL at 8 weeks of treatment ( primary endpoint ) .\n\nLabels: 2\n\nSample: We aimed to assess the effects of an enteral glucose supply on protein synthesis , proteolytic pathways , and proteome in human duodenal mucosa .\n\nLabels: 3\n\nSample: No differences were found between GPi DBS and STN DBS on the other neuropsychological tests .\n\nLabels: 4\n\nSample: The primary outcomes were the physical and the mental summary scales of the SF-36 .\n\nLabels: 4\n\nSample: Heart rates were comparable between groups , except after induction and after start of the procedure in which they were higher with ketamine-midazolam ( P < 0.05 ) .\n\nLabels: 4\n\nSample: Despite being comparable pretreatment , only the SIT group had a significant decrease in recollected total drug use during SIT .\n\nLabels: 4\n\nSample: Study groups were determined by subject BP , including hypertension ( BP > or = 95th percentile ) , borderline hypertension ( BP 75 to 95th percentile ) , and severe ADPKD ( BP < or = 75th percentile with > 10 renal cysts ) .\n\nLabels: 2\n\nSample: Doses of UH between 150 and 566 U/kg achieved therapeutic anti-Xa activity ( 0.35-0 .7 U/mL ) .\n\nLabels: 4\n\nSample: See Instructions for Authors for a complete description of levels of evidence .\n\nLabels: 2\n<Assistant>Noted. I'll remember these details.", "[Dialogue between User and Assistant on 2024-01-09 00:00]\n<User>I want you to learn from these classified examples:\n\nSample: No evidence was seen for an increase in serious or opportunistic infections .\n\nLabels: 4\n\nSample: As a follow-up in 1992 , fluorosis examinations using Dean 's index were conducted on 448 remaining subjects .\n\nLabels: 2\n\nSample: Patients received stimulation with either an asymmetric biphasic ( A ) or symmetric biphasic ( B ) square-wave pulse .\n\nLabels: 2\n\nSample: A total of 19,820 attacks were treated with telcagepant ( mean per patient = 31 ) and 10,981 with rizatriptan ( mean per patient = 35 ) .\n\nLabels: 4\n\nSample: Eighty-three percent of subjects completed the study ( 291 of 350 enrolled ) .\n\nLabels: 4\n\nSample: Changes in knowledge and skills were only weakly associated with improvements in guideline adherence .\n\nLabels: 4\n\nSample: During positive emotional image presentation there were significant differences between placebo and HT conditions within the medial frontal cortex .\n\nLabels: 4\n\nSample: Overall , short-term administration of QVA149 showed a good cardiovascular safety and tolerability profile in healthy subjects .\n\nLabels: 1\n\nSample: This analysis included 38,319 singleton pregnancies , of which 3,304 ( 8.6 % ) were preterm deliveries ( less than 37 completed weeks ) enrolled in the World Health Organization randomized trial of a new antenatal care model .\n\nLabels: 2\n\nSample: The rates of the combined primary end point of death , myocardial infarction , or recurrent ischemia after nine days were 27.9 % , 35.9 % , 34.7 % , 30.3 % , and 35.7 % in patients allocated to fondaparinux doses of 2.5 , 4 , 8 , and 12 mg and enoxaparin , respectively ( p = NS ) .\n\nLabels: 4\n\nSample: The primary outcome was ` blinded ' withdrawal of study drug due to unacceptable glycemic control ; GHb , glucose tolerance , lipids , and quality of life were also assessed .\n\nLabels: 2\n\nSample: Magnesium sulfate favorably affects rate control and seems to promote the conversion of long lasting episodes of paroxysmal atrial fibrillation to sinus rhythm , representing a safe , reliable and cost-effective alternative treatment strategy to diltiazem .\n\nLabels: 1\n\nSample: Optimal GH replacement , defined as treatment resulting in normalization of serum insulin-like growth factor-I ( IGF-I ) concentration , was achieved in 25 patients .\n\nLabels: 4\n\nSample: Evaluations of patient orientation and sedation were similar between the experimental and control groups .\n\nLabels: 4\n\nSample: The overall response rate was 52.9 % .\n\nLabels: 4\n\nSample: Subjects were randomized into three groups to receive 250 mg BID of plain or slow release ascorbic acid tablets or placebo daily for two months .\n\nLabels: 2\n\nSample: The implant of intraocular lenses ( IOLs ) following cataract surgery induces a foreign-body reaction to the IOL and a response on the part of the lens epithelial cells ( LECs ) .\n\nLabels: 0\n\nSample: Many children may be at heightened risk for fire and scald burns by virtue of their home environment .\n\nLabels: 1\n\nSample: There were no statistical differences by training modality for either mask regarding ease of fit or success of fit .\n\nLabels: 4\n\nSample: In addition , patients were treated with six cycles of CMF therapy .\n\nLabels: 2\n\nSample: 2 only ) [ corrected ] and before ( 0 h ) and 1 , 2 , 4 and 6 h after the fat intake for the determination of triglyceride ( TG ) , apolipoprotein B-48 ( apoB48 ) , remnant-like particle-TG ( RLP-TG ) , lactate , free fatty acid ( FFA ) , insulin , and glucose .\n\nLabels: 2\n\nSample: Clinical characteristics and vascular anatomy of CLI patients with ischaemic skin lesions who were unsuitable for revascularisation therapy show little variations by region of origin and diabetic status .\n\nLabels: 1\n\nSample: The difference in total cost per patient between day care and inpatient care was small ( 1789 Pounds ( 1539 Pounds to 2027 Pounds ) v 2021 Pounds ( 1834 Pounds to 2230 Pounds ) ) .\n\nLabels: 4\n\nSample: In total , 3 failures were observed in the form of debonding ( n = 1 ) and fracture ( n = 2 ) in the group of resin composite laminate veneers .\n\nLabels: 4\n\nSample: The PTM has potential to be an alternative to traditional physical/occupational therapy , although it is premature to recommend widespread use of this model in other regions .\n\nLabels: 1\n\nSample: Epworth Sleepiness Scale ( ESS ) scores and the Functional Outcomes of Sleep Questionnaire ( FOSQ ) scores were obtained at baseline , 1 month after randomization , and again after initiation of fixed CPAP in control subjects and after the sleep study in auto-CPAP patients .\n\nLabels: 2\n\nSample: Neither of the mentioned parameters changed significantly in the increased VE group .\n\nLabels: 4\n\nSample: As of October 1 , 1994 , 39 of the 50 patients assigned to chemoembolization and 40 of the 46 patients assigned to conservative management had died .\n\nLabels: 4\n\nSample: The purpose of this study was to examine the effects of 9 months of twice-weekly exercise training on strength , arm ergometry performance , and indices of psychological well-being and quality of life .\n\nLabels: 3\n\nSample: One hundred sixty-two infertile male patients with varicocele .\n\nLabels: 2\n<Assistant>I've processed this information and will remember it.", "[Dialogue between User and Assistant on 2024-01-10 00:00]\n<User>Here are training examples for classification. Note the labels carefully:\n\nSample: Steroid 5-reductase inhibitors are used to treat benign prostatic hyperplasia and androgenic alopecia , but the role of 5-dihydrotestosterone ( DHT ) in mediating testosterone 's effects on muscle , sexual function , erythropoiesis , and other androgen-dependent processes remains poorly understood .\n\nLabels: 0\n\nSample: Future studies will be necessary to determine the possible clinical and functional implications of these results .\n\nLabels: 1\n\nSample: Twenty-eight of 90 patients ( 31 % ) had evidence of bone metastases by bone scan .\n\nLabels: 4\n\nSample: Statistically lower change was noted in spherical aberration ( 0.011 m ) in the OPA group versus the OATz group ( 0.099 m ) ( P < .001 ) .\n\nLabels: 4\n\nSample: A campaign by a local tractor and equipment dealership to encourage farmers to purchase and install ROPS and seatbelt retrofit kits for older tractors .\n\nLabels: 2\n\nSample: The HSI can be used in health care settings to identify individuals at risk for HIV and to initiate HIV testing , early care , and risk-reduction counseling , necessary goals for effective HIV prevention efforts .\n\nLabels: 1\n\nSample: The prognostic significance of MGMT promoter methylation was equally strong in the RT arm and the RT/PCV arm for both progression-free survival and overall survival .\n\nLabels: 4\n\nSample: Medications were administered employing open-label design and flexible dosages , but with blind raters .\n\nLabels: 2\n\nSample: Patients were allocated randomly to receive daily subcutaneous injections with either saline ( n = 8 ) or rhGM-CSF 2.8 microg per kg body-weight ( n = 8 ) from 3 days before operation until 4 days afterwards .\n\nLabels: 2\n\nSample: It is known that several mechanisms are involved in the pathogenesis of IBS .\n\nLabels: 3\n\nSample: The online quizzes were administered to first-professional year pharmacy students in fall 2004 and fall 2005 .\n\nLabels: 2\n\nSample: The distance output of the monitors is inaccurate and should be noted with caution .\n\nLabels: 1\n\nSample: After successful stenting of 327 coronary lesions in 282 consecutive patients , the patients were randomized to receive ticlopidine ( 200 mg/day ) or cilostazol ( 200 mg/day ) .\n\nLabels: 4\n\nSample: Infants receiving intravenous antifungal prophylaxis were pre-identified during enrollment in the parent study .\n\nLabels: 2\n\nSample: Veterans Health Administration ( VA ) healthcare was used by 31.1 % of PTSD-positives and 11.4 % of PTSD-negatives ( p < 0.001 ) .\n\nLabels: 4\n\nSample: One hundred women of > 40 years undergoing assisted reproduction treatment were randomized between a GH treatment group and a placebo group .\n\nLabels: 2\n\nSample: This study aimed to investigate whether quality of life and cardiac function were affected by an upgrade to dual chamber pacing ( DDDR or DDIR ) following long-term ventricular stimulation .\n\nLabels: 3\n\nSample: Study results and review of the literature support the development of pediatric formulations of NSAIDs with greater COX-2 selectivity to improve postsurgical pain relief for children .\n\nLabels: 1\n\nSample: Over the last few years , a new generation of high-resolution ultrasound platforms with the `` power-mode '' feature has become available , that also enables the imaging of small vessel blood flow .\n\nLabels: 3\n\nSample: The benefit demonstrated in frequency of obstruction , severity of obstruction , and overall ability to breathe ( P < .05 ) was maintained at 2 years .\n\nLabels: 4\n\nSample: Randomization was performed according to birth date .\n\nLabels: 2\n\nSample: The results of the present study indicate that AA tends to inactivate the sympathetic nervous activity demonstrated by both HRV and meridian electrical conductance changes .\n\nLabels: 1\n\nSample: In a cross-over , double-blinded randomized study we tested whether 2-week periods of 5 , 25 or 50 Hz TENS applied to wrist flexor muscles , improved the score of the Fahn-Tolosa-Marin scale of nine patients with PWT .\n\nLabels: 2\n\nSample: Administration of a feeding formula enriched with fish oil was associated with decreased progression of pressure ulcers and a decrease in blood concentrations of C-reactive protein .\n\nLabels: 1\n\nSample: With repeated-measures analysis of variance , ciclesonide produced a significant decrease in alveolar nitric oxide and a significant improvement in ACT scores over time .\n\nLabels: 4\n\nSample: Pharmacokinetic studies showed no influence of gemcitabine on the pharmacokinetic parameters of Cilengitide and vice versa .\n\nLabels: 4\n\nSample: Group RCT .\n\nLabels: 2\n\nSample: PACIC is positively associated with quality of life , so efforts to align care with the Chronic Care Model may benefit this population .\n\nLabels: 1\n\nSample: We examined the influence of supplementation with selenomethionine on soluble tumor necrosis factor-alpha receptor type 1 ( sTNF-R1 ) and C-reactive protein ( CRP ) concentrations in patients with psoriasis who were treated with narrowband ultraviolet B.\n\nLabels: 3\n\nSample: Participants had a clinician diagnosis of COPD and had either been hospitalised or taken steroids or antibiotics for COPD in the previous three years ; their median age was 71 years .\n\nLabels: 2\n\nSample: For the first molar , anesthetic success for the IAN + mock IO and the IAN + IO etidocaine hydrochloride groups , respectively , were 81 % and 100 % .\n\nLabels: 4\n\nSample: The change in lung function ( FEV1 ) , bronchial response to MCh and adenosine monophosphate ( AMP ) , the fraction of nitric oxide in exhaled air ( FENO ) and quality of life ( QOL ) scores were measured .\n\nLabels: 2\n\nSample: The authors evaluated long-term clinical outcomes in selected acutely comatose patients with severe diffuse brain swelling and recent clinical signs of impending brain death who received a novel high-dose mannitol treatment compared with those who received conventional-dose mannitol in the emergency room .\n\nLabels: 3\n\nSample: Significant additional benefits of Comb over MedMgt and of Beh over CC were not found .\n\nLabels: 4\n\nSample: Primary endpoint is the number of re-operations within 12 months .\n\nLabels: 2\n\nSample: Data also indicate the intervention may help prevent treatment attrition .\n\nLabels: 1\n\nSample: At the end of therapy , five of 14 or 36 % of patients in group A versus 0 of 15 in group B had both normal serum ALT and nondetectable HCV RNA by polymerase chain reaction ( p = 0.017 ) .\n\nLabels: 4\n\nSample: Academic tertiary referral center .\n\nLabels: 2\n\nSample: The goal was to change ( or prevent ) related risk behaviors and the psychosocial variables that theoretically influence those behaviors .\n\nLabels: 3\n\nSample: A reduction of the acquisition time of almost 45 % could be achieved without substantial loss of quantitative motion information .\n\nLabels: 1\n\nSample: BMD of both femurs was measured using dual energy X-ray absorptiometry ( DXA ) before and after 12months of exercise , by an observer blind to the leg allocation .\n\nLabels: 2\n\nSample: Tumor tissue was assayed for EGFR expression by immunohistochemistry .\n\nLabels: 2\n\nSample: At week 52 , treatment with rituximab in both dose groups showed significant improvements in the HAQ DI compared to the MTX alone group ( -0.905 and -0.916 in the rituximab 500 mg plus MTX and 1,000 mg plus MTX groups , respectively , versus -0.628 in the MTX alone group ; P < 0.0001 ) .\n\nLabels: 4\n\nSample: No correlation was found between any of the satiety scores at any time-point with their comparable ghrelin levels .\n\nLabels: 4\n\nSample: Side effects and postoperative analgesic requirement ( tramadol , intramuscular ) also were recorded .\n\nLabels: 2\n\nSample: The reviewing function of the intervention was weak and sometimes failed to solve problems in the development of liaison or recall .\n\nLabels: 4\n<Assistant>I've captured all of this valuable information."]
[{"question": "Sentence: Cumulative incidence of ESRD from 5 different starting points : eGFR of 30 and 15mL/min/1 .73 m ( 2 ) and 1-year ESRD risk of 5 % , 10 % , and 20 % , estimated by a published 4-variable kidney failure risk equation .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: To assess efficacy and tolerability of FPND in the treatment of bilateral nasal polyposis in adults .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: The accelerometer data were categorized as either sedentary or non-sedentary minutes using six previously studied cut-points : 100 counts-per-minute ( CPM ) , 200 CPM , 300 CPM , 500 CPM , 800 CPM and 1100 CPM .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: A high-frequency steady-state visual evoked potential ( SSVEP ) has been suggested for the reduction of eye fatigue for SSVEP-based brain-computer interfaces ( BCIs ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: Significantly more effective ventilations ( visible chest rise ) were delivered using MMV ( 91 % ) when compared to MPV ( 79 % , P < 0.001 ) and BMV ( 59 % , P < 0.001 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Public-sector psychiatric patients with long histories of antipsychotic treatment and presumably long-standing tardive dyskinesia were randomly assigned to receive branched-chain amino acids or placebo .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: This randomized controlled trial aims to compare hand-assisted laparoscopic colectomy ( HALC ) with open colectomy ( OC ) in the management of right-sided colonic cancer .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: The groups were comparable in the etiology of heart disease , in the use of revascularization procedures , the use of balloon counterpulsation , and APACHE-II score ( 33 5 vs. 33 4 ) and SOFA score ( 11 1 vs. 11 1 ) at inclusion ; however , more patients in SC were subject to resuscitation before inclusion .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: A conceptual clarification of the domain of social relationships defines three aspects of social relationships ( structure , function and quality ) , which have both alcohol-specific and general components .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: In UC-MP , 12.5 % vs 14.1 % of patients receiving abatacept vs placebo were in remission at week 52 .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: After 24-week treatment , the clinical effect and safety were evaluated using the International Prostatic Symptom Score ( I-PSS ) , quality of life ( QOL ) , maximum flow rate ( Qmax ) , average flow rate ( Qave ) , residual urine volume ( RUV ) , total prostatic volume ( TPV ) , etc. .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: No adverse effects were reported in either group .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: This study compared the efficacy of the COX-2 specific inhibitor valdecoxib with naproxen and placebo , in treating symptomatic OA of the hip .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: Adverse effects at the application site were observed in subjects randomized to benvitimod 5mg q.d and b.i.d , but there were no observable dose effects in the dose-range evaluated .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Impaired fasting glucose patients with high cardiovascular risk may receive the greatest benefits from concomitant treatment with a statin and metformin .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: At the start of the run-in period ( and for the entire length of the study ) , rHuEpo administration was withdrawn ; patients whose haemoglobin ( Hb ) levels dropped at a level < 8.0 g/dl at one single monthly check , had to be withdrawn from the study .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Deficits in emotion regulation skills are possible factors maintaining major depressive disorder ( MDD ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Practices were randomized to receive either the intervention for hyperlipidaemia or for hypertension ; practices acted as control for the intervention not received .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: The fact that only a subgroup of these patients develops pathological gambling suggests an interaction between dopaminergic drug treatment and individual susceptibility factors .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: At baseline , daily hot flush frequency was 2.92.1 for the S - ( - ) equol group and 3.22.4 for the placebo group .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The effect of Chinese herbs was estimated by observing the recurrence rate of disease and side-effects of prednisone .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Finally , we analyzed the patient population suitable for this therapy according to the relationship between the grouping of patient body weight and curative effect .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Postmenopausal women had significantly higher total BF and percentage BF than did pre - and perimenopausal women .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Trial eligibility and compliance to inclusion were registered .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Noninferiority between the two treatments was demonstrated by similar CR rates ( P = 0.487 ) in the overall period .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: This study builds on past research by investigating the impact of Playworks separately for girls and boys .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Local irradiation has been reported to yield excellent relief of symptoms in 100 % of patients with hematuria , 80 % with urinary outflow obstruction , and 50-70 % with ureteral obstruction or pelvic pain secondary to locally advanced prostatic carcinoma .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: A significant reverse correlation between changes in serum 25 ( OH ) D concentrations and body fat mass was observed ( r = -0.319 , P = 0.005 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The decrease in gastric acidity during the daytime and during the total 24-hour period by all three treatments was significantly greater than after placebo ; a significant difference in acid inhibition was found between ranitidine and 40 mg omeprazole , but not between ranitidine and 20 mg omeprazole , nor between the two doses of omeprazole .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The quality improvement in INR control versus baseline was similar in the four groups .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: The purpose of this study is to determine whether having a history of incarceration affects response to primary care office-based buprenorphine/naloxone treatment .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: - 64.47 g.min / ml and placebo treatment .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Additionally , no patient in the treatment group developed chronic iliac crest dysesthesias ( 0 of 9 ) versus 7 of 10 patients ( 70 % ) in the control group ( P < 0.05 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Plasma insulin was greater in group T than in the PS and CPAP groups ( P < 0.01 and P < 0.01 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Patients received a combination of cisplatin ( 100 mg/m2 at d1 and d24 , 200 mg/m2 in total ) , vinblastine ( 4 mg/m2 at d1 and d24 , 8 mg/m2 in total ) , 5-fluorouracil in continuous infusion ( 1,000 mg/m2 from d1 to d3 , and from d24 to 26 , 6,000 mg/m2 in total ) and bifractionated radiotherapy ( two series of 21 Gy/14 fractions/9 days , 11 days apart ) followed by a new evaluation and surgical excision .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Bacterial endotoxins can induce the synthesis and release of vascular endothelial growth factor ( VEGF ) , which may alter vascular permeability and cause vascular leakage .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: For the first time , we have shown that the initial glycaemic response is reduced after a meal with higher compared with a meal with lower fat content in adolescents with T1DM given a rapid-acting insulin analogue preprandially .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: The probability of physically aggressive behavior for patients in the intervention group decreased from 0.27 to 0.12 .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Eyes with the aspheric IOL had lower spherical aberration than eyes with the spherical IOL and , related to that , a smaller myopic shift .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Because of a decline in estradiol levels , premenopausal , perimenopausal , and postmenopausal women experience symptoms related to vasomotor instability .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: Patients were randomly assigned to one of 2 groups with 25 patients in each group .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Of the remaining 41 N0-1 patients , 3 had disease progression and received no further therapy .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: These differences were not statistically significant .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Intervention in the TDM group involved patient follow-up by a clinical pharmacist to obtain and pharmacokinetically interpret serum vancomycin concentrations for dosage individualization .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Neuropsychological evaluation showed no significant differences between patients treated with dexamethasone and placebo .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Complications and need for supplement was noted .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Systolic arterial pressure was maintained more closely in the target range in the metaraminol group compared with the ephedrine group .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: To investigate whether exposure to a smoking-related facial age-progression technique impacts on quit smoking cognitions , nicotine dependence , and self-reported and objectively assessed smoking in young women in a randomized controlled trial .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: The interleukin-6 production differed significantly between group C and group F.\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Liver function tests -- total bilirubin ( T Bil ) , gamma GT ( GGT ) , albumin , alkaline phosphatase ( ALP ) , aspartate transferase ( AST ) , alanine transferase ( ALT ) -- and creatine kinase levels were obtained preoperatively and at 1 , 24 , 48 , and 72 hours postoperatively .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Study results should be available at the end of 2011 .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The mean increase in serum creatinine 48 hours after angiography was significantly greater in the furosemide group ( P = 0.01 ) than in the saline group .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Bleeding complications in AT-treated patients with and without DIC were higher compared with placebo ( major bleeding rates : 7.0 % vs. 5.2 % for patients with DIC , P = 0.6 ; 9.8 % vs. 3.1 % for patients without DIC , P = 0.02 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Etanercept monotherapy ameliorates disease activity in GC nave patients with PMR .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Statistically significant improvements were only noted in Group I ( p < 0.05 ) in the Timed `` Up & Go '' test score ( 27 vs. 20 sec . )\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: To study and compare the effects of complete nasal packing and nasal packing with airways ( uni/bilateral ) on blood pressure , arterial oxygen saturation , middle ear pressure , and post-operative subjective complaints .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: The 1-lpm group 's Spo2 range was 89-99 % .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Twenty-two patients were evaluable for a planned interim analysis .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: This study determines if 1-year administration of a replacement dose of dehydroepiandrosterone , 50 mg/d , orally administered , could have a beneficial influence on several determinants of the muscular function altered during aging .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Substantial improvement was more frequent with t-PA among lesions containing apparent thrombus ( in 36 % with t-PA versus 15 % with placebo ; p < 0.01 ) , as it was among patients evolving a non-Q wave MI ( 33 % versus 8 % ; p < 0.005 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Ultrathin flap LASIK and LASEK were randomly selected to treat high myopic patients with corneal thickness between 450 and 500 microm .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: This study tested the efficacy of an intervention for anxious adolescent boys experiencing bullying at school .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: During the follow-up period , overall 725 ventricular tachycardia ( VT ) / ventricular fibrillation ( VF ) episodes were recorded in 45 ( 49 % ) of 92 patients .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Combination of ondansetron and dexamethasone was more efficacious compared to ondansetron alone in the prevention of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Single dose of botulinum toxin type A ( Botox ) ( 200 or 300 U ) or placebo .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: This multicentre , double-blind , active-controlled study randomized 2639 patients aged 18-80 years to 104 weeks of treatment with metformin in addition to alogliptin 12.5 mg once daily ( n = 880 ) , alogliptin 25 mg once daily ( n = 885 ) or glipizide 5 mg once daily , titrated to a maximum of 20 mg ( n = 874 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Although we detected no significant difference between groups at 1 month after vaccine course , MenACWY-CRM and 4CMenB vaccines reduced meningococcal carriage rates during 12 months after vaccination and therefore might affect transmission when widely implemented .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: The primary end point occurred in 34.6 % of the patients in the monitoring group , as compared with 31.1 % of those in the conventional-treatment group ( hazard ratio , 1.13 ; 95 % confidence interval [ CI ] , 0.98 to 1.29 ; P = 0.10 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The duration of mechanical ventilation following operation in the MFU group was shorter than that in the control group ( 28.6 + / - 9.1 hrs vs 32.3 + / - 8.7 hrs ; P < 0.05 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Secondary outcome is further treatment seeking .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Hemodynamic parameters , oxygen saturation and tympanic temperature were measured and recorded before induction of anesthesia and at regular intervals thereafter .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: In particular , to discover whether a computerised assessment overestimates or underestimates the prevalence of psychiatric morbidity in relation to a human interviewer .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: The new model of the neck brace reduces the number of baseplate replacements during hands-free speech and is considered as a helpful device by 81 % of the participants .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Information about an increased risk of strut fracture does not induce psychological distress among well informed recipients of BScc valves .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Mean Hb concentration , severe anaemia , parasite prevalence , and anthropometric measurements were similar in each group .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The object of this analysis was to assess the possible correlation between iridium-192 source non-centering and angiographic-determined restenosis .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: To study the effect of dietary supplementation with PS on cholesterol and glucose metabolism in humans .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: Significant condition x time interaction effects were observed , indicating a decrease in platelet counts and an increase in diastolic blood pressure after the lymphatic treatment protocol [ corrected ] .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: This urinary metabolite ratio has previously been shown to be correlated with caffeine clearance .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Aerosolized bupivacaine significantly reduced postoperative pain in comparison with all other treatments ( p < 0.05 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Thirty ( 16 % ) versus 36 ( 20 % ) had received further surgical treatment : 9 ( 5 % ) compared with 25 ( 14 % ) had had a hysterectomy and 21 ( 11 % ) versus 11 ( 6 % ) had received repeat ablation .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The blood flow velocity of the superficial temporal artery was measured by means of a Doppler detector in 30 healthy volunteers under 2 different conditions , with and without the face pad .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Examine weight change in subjects receiving variable doses of transdermal nicotine replacement for smoking cessation .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: Overall success was achieved in 35 patients with the initial treatment ( i.e. , four treated with CVD , seven with KA/VE , 14 with TEC , and 10 with TEE ) and in nine more patients with a second-line regimen ( i.e. , two with CVD , five with KA/VE , and two with TEC ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Analgesic requirements and prostaglandin-related side effects were similar between groups .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Before and after 1 month , the snorers rated their daytime tiredness and completed the Nottingham Health Profile questionnaire .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: After six weeks both systolic and diastolic BP were effectively reduced by both treatments .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Fifteen eyes ( 12.5 % ) were excluded from the postoperative visits regime : 11 cases ( 18.9 % ) in the group of two visits and 4 cases ( 6.45 % ) in the group of three visits .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Adapalene gel 0.1 % was effective in the treatment of acne vulgaris in Japanese patients .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: The lack of sedative effects in the presence of marked analgesia was surprising in comparison with results of previous studies .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: The cost of PIC in Sweden is nearly five times greater than the cost of IOC .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: A traditional Ayurvedic supplement formulated to reduce sleep onset insomnia .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Twenty-three participants ( mean age 24 years ; SD 1.86 ; 14 females ) were exposed to 30 h of sleep deprivation during which they conducted physiological , social and cognitive tasks .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Liver biopsies were performed after administration of factor VIII or IX , before and 24 weeks after cessation of antiviral therapy .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Changes from baseline to posttest were compared in the treatment and control groups using analysis of variance .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Cerebral and cerebellar perfusions were calculated for each ROI using average number of counts per pixel .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: For a patient of known weight , one can calculate the iodine dose needed to provide a desired level of hepatic enhancement .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: There was no difference in post-test subscores for modules completed using the ` construct table ' format ( 78.1 + / - 1.4 ) or the ` table provided ' format ( 76.1 + / - 1.4 ; CI - 1.1 to 5.0 , P = 0.21 ) , and wholist and analytic styles had no interaction ( P = 0.75 ) or main effect ( P = 0.18 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Although follow-up medical care costs were $ 2200/patient lower with brachytherapy , total costs remained higher at 1 year ( $ 28 543 versus $ 26 737 , P = 0.46 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: There were significant differences between HIV-infected and uninfected women , with the former having less education , a history of more stillbirths , more STIs , and in this pregnancy , a lower BWT ( 2949 vs 3100 g , P < .0001 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}]