["[Dialogue between User and Assistant on 2024-01-01 00:00]\n<User>These labeled training examples are for classification:\n\nSample: The oxidative and inflammatory effects of iron during haemodialysis were also assessed .\n\nLabels: 3\n\nSample: Randomized , double-blind , placebo-controlled , intention-to-treat trial conducted between March 1998 and October 1999 in 40 medical centers in the United States .\n\nLabels: 2\n\nSample: Data were collected as part of a randomised controlled trial .\n\nLabels: 2\n\nSample: After the follow up ( > 2 years ) , the severity of ocular surface conditions was significantly milder in patients in group A than in group B ( P < 0.01 ) .\n\nLabels: 4\n\nSample: The qualitative results favoured lemon juice in reducing the amount of interfering extra-cardiac activity .\n\nLabels: 4\n\nSample: The goal was to identify emergent clinical characteristics of patients with definitive suicidal behavior ( DSB : preparatory act , suicide attempt , completed suicide ) .\n\nLabels: 0\n\nSample: There was a significant correlation between the greatest percentage fall in forced expiratory volume in 1 s ( FEV ( 1 ) ) ( r = 0.6 , P < 0.0001 ) , the dose-response slope ( r = 0.73 ) , cumulative dose ( r = 0.55 ) and PD15 ( r = 0.46 ) for mannitol and hypertonic saline .\n\nLabels: 4\n\nSample: A total of 42,376 men were randomized to systematic screening or usual care .\n\nLabels: 2\n\nSample: Apart from direct protection and reduced productivity loss during epidemics , the main reason to immunize healthcare workers ( HCWs ) against influenza is to provide indirect protection of frail patients through reduced transmission in healthcare settings .\n\nLabels: 0\n\nSample: Anesthesia was maintained with a mixture of oxygen and air and either enflurane or halothane .\n\nLabels: 2\n\nSample: Staging for liver fibrosis is recommended in the management of hepatitis C as an argument for treatment priority .\n\nLabels: 3\n\nSample: Immediate post-ICBS scores ( intervention group only ) significantly increased to 82 % ( p < 0.001 ) .\n\nLabels: 4\n\nSample: Thirty-four patients were randomized 1:1 to receive no glucose ( 0G group ) or low-dose glucose ( 0.1 g/kg/h for 1h followed by 0.05 g/kg/h for 1h ; LG group ) .\n\nLabels: 2\n\nSample: Furthermore , the decreases in absolute count of T suppressor cells plus cytotoxic T lymphocytes , and T helper cells in the TCM group were significantly lower than those in the placebo group after they took the capsules for 16 weeks ( both p < 0.05 ) .\n\nLabels: 4\n\nSample: 85 preterm infants were included in this study .\n\nLabels: 2\n\nSample: A dose-response relationship was observed with higher patch doses , which produced a higher percentage of cotinine replacement and better withdrawal symptom relief .\n\nLabels: 4\n\nSample: Patients were randomized at entry into the original study in 1986 to blinded treatment for 2 years with either a calcium ( placebo ) or an intermittent cyclical etidronate regimen , which most patients continued for a third year .\n\nLabels: 2\n\nSample: To compare the effect of monovision correction and multifocal intraocular lens ( IOL ) implantation on patient satisfaction , spectacle dependence , visual acuity , and dysphotopsia in cataract patients .\n\nLabels: 3\n\nSample: The new Biovision B-Scan Probe has greater resolution than its predecessors because of its posteriorly placed focus ( 25 mm inside the eye ) and the consequent reduction in size of the sound field .\n\nLabels: 3\n\nSample: Data were analyzed in a masked fashion .\n\nLabels: 2\n\nSample: This study examined whether short-term supplementation with pomegranate juice and extract is safe and well tolerated by MHD patients .\n\nLabels: 3\n\nSample: This study aimed to determine whether focused , scheduled telephone counselling during the first 3 months after MTBI decreases symptoms and improves functioning at 6 months .\n\nLabels: 0\n\nSample: Baseline features were comparable in both groups .\n\nLabels: 4\n\nSample: The aim of this study was to assess the effects of prophylactic polypropylene mesh in morbidly obese patients undergoing gastric by-pass surgery .\n\nLabels: 0\n\nSample: There are strong indications that the homeopathic after-bite gel reduces erythema development following mosquito bites .\n\nLabels: 4\n\nSample: Data from 255 edentate elders who participated in a randomised clinical trial were used .\n\nLabels: 2\n\nSample: Polyurethane cuffed endotracheal tubes can reduce the frequency of early postoperative pneumonia in cardiac surgical patients .\n\nLabels: 1\n\nSample: All efficacy variables improved progressively throughout the study .\n\nLabels: 4\n\nSample: Twenty-three rural health centres were stratified prior to random allocation to the new ( n = 11 ) or standard ( n = 12 ) model of care .\n\nLabels: 2\n\nSample: The primary efficacy endpoint was the proportion of patients with a complete response ( CR ; defined as no emetic episodes and no rescue medication ) during the first 24 hours after chemotherapy .\n\nLabels: 2\n\nSample: Each restoration was independently evaluated in terms of retention and the presence of caries at baseline and at 1 , 6 , 12 , and 24 months .\n\nLabels: 2\n\nSample: Between 1995 and 1996 , 100 patients were randomized to receive a prophylactic therapy for prevention of heterotopic ossification .\n\nLabels: 2\n\nSample: Prostate cancer ( PC ) screening with prostate-specific antigen ( PSA ) has been shown to decrease PC mortality by the European Randomized Study of Screening for Prostate Cancer ( ERSPC ) .\n\nLabels: 0\n\nSample: In 30 months , 3,298 patients were enrolled ( n = 1,649 in each arm ) .\n\nLabels: 4\n\nSample: Patients treated with celecoxib had lower pain scores than controls , pain scores correlating with local PGE2 level .\n\nLabels: 1\n\nSample: Repeat-sprint ability ( 6 20 m ) , countermovement and squat jumps , perceived muscle soreness , and fatigue were measured pretraining and over 48 h posttraining .\n\nLabels: 2\n\nSample: HIV prevalence was 19.8 % and 18.4 % , respectively , at businesses randomised to on-site and off-site VCT .\n\nLabels: 4\n\nSample: Primary baseline factors evaluated were CD4 cell count , vRNA level , gender , race , and age , using multivariable Cox , log-binomial , and linear regression models .\n\nLabels: 2\n\nSample: The relationship between baseline T2LV and Expanded Disability Status Scale ( EDSS ) was not significantly different between patients with RRMS and SPMS .\n\nLabels: 4\n\nSample: Primary end point was pain at 3 weeks , measured as the bodily pain subscale of Short Form-36 ( SF-36 ) .\n\nLabels: 2\n\nSample: This was a prospective study of 110 patients with early RA who were participating in the COBRA ( Combinatietherapie Bij Reumatode Artritis ) clinical trial and followup study , a randomized controlled trial comparing the efficacy of oral pulse prednisolone , methotrexate , plus sulfasalazine with sulfasalazine alone .\n\nLabels: 2\n\nSample: There was no evidence for such treatment difference in AG ( HR , 1.16 ; 95 % CI , 0.75 to 1.79 ; P = 0.69 ) and AA ( HR , 0.63 ; 95 % CI , 0.36 to 1.11 ; P = 0.11 ) patients .\n\nLabels: 4\n\nSample: Amoxiicillin with clavulanic acid in the treatment of patients with severe chronic obstructive pulmonary disease exacerbation .\n\nLabels: 0\n\nSample: In the intervention group , practice nurses ( PNs ) will be trained for their enhanced roles in this nurse-led collaborative care study .\n\nLabels: 2\n\nSample: This bronchoprotection diminished with regular treatment , although it remained significant ( P < .01 ) compared with placebo ( 68 microg ) versus salmeterol ( 144 microg , a 2.1-fold difference [ 95 % CI 1.2 to 3.8 ] ) and versus formoterol ( 230 microg , 3.4-fold difference [ 95 % CI 1.9 to 6.2 ] ) .\n\nLabels: 4\n\nSample: No study drug-related serious adverse events were observed .\n\nLabels: 4\n\nSample: However , they were less ill ( APACHE II score 17.2 vs 20.6 , P = 0.008 ) and had less severe renal failure at entry ( creatinine clearance 14 ml/min vs 4 ml/min , P < 0.0001 ) .\n\nLabels: 4\n\nSample: Carboplatin exposure-intensity was defined by substituting cumulative carboplatin exposure for total dose .\n\nLabels: 2\n\nSample: The subsequent 30 patients were randomly allocated to receive an intravenous bolus of 250 microg/kg lidocaine followed by an infusion of 13 microg x kg ( -1 ) x h ( -1 ) lidocaine or an equivalent volume of saline when shivering was observed .\n\nLabels: 2\n\nSample: ( These analyses are all on an intention-to-treat basis . )\n\nLabels: 4\n<Assistant>Appreciated. I'll retain these important details.", "[Dialogue between User and Assistant on 2024-01-02 00:00]\n<User>These are labeled examples for classification tasks:\n\nSample: No change was noted in all spectral densities in both cooling conditions , and only neurogenic spectral density increased without cooling .\n\nLabels: 4\n\nSample: The primary outcome was the proportion of the standardized estimated energy requirement that was delivered as enteral nutrition .\n\nLabels: 4\n\nSample: Cardiac resynchronization therapy ( CRT ) efficacy trials to date used atrial-synchronous biventricular pacing wherein there is no or minimal atrial pacing .\n\nLabels: 0\n\nSample: On day 6 , a single 40 mg dose of pravastatin was administered orally .\n\nLabels: 2\n\nSample: Media Smart achieved a reduction in eating disorder risk factors for high-depression participants and a reduced rate of growth in risk factor scores for low-depression participants .\n\nLabels: 1\n\nSample: Over the subsequent year , there were no significant differences in the total number of visits or telephone calls to the Family Practice Clinic by either group .\n\nLabels: 4\n\nSample: Eligibility criteria included early stage diagnosis , enrollment during last treatment visit , and the ability to receive the intervention in English .\n\nLabels: 2\n\nSample: Resistance exercise has been shown to increase arterial stiffness acutely with no definitive cause .\n\nLabels: 3\n\nSample: This review summarizes the key findings from the Collaborative Initial Glaucoma Treatment Study ( CIGTS ) , which was designed to evaluate whether medical therapy or trabeculectomy is the better initial treatment for patients with open-angle glaucoma ( OAG ) .\n\nLabels: 3\n\nSample: Patients had moderate symptoms of degenerative lumbar conditions ( mean LSS symptom score = 2.67 , SD = 0.71 ) and reported some difficulties with low back function ( mean LSS function score = 1.99 , SD = 0.61 ) .\n\nLabels: 4\n\nSample: Moreover , A peak of the treatment group after treatment was significantly lower < ( P < 0.05 ) and E/A ratio was significantly higher ( < P < 0.05 ) as compared with those of the control group .\n\nLabels: 4\n\nSample: Increasing sn-2 palmitate in infant formula reduces stool palmitate soaps .\n\nLabels: 1\n\nSample: The IOP was measured at the beginning of the study ( t-1 ) , after 15 days of pretreatment with placebo or PEA ( t0 ) , and at 15 , 30 , and 120 min after the iridotomy ( t1 , t2 , t3 ) .\n\nLabels: 2\n\nSample: The control participants received no further intervention , whereas training participants attended a weekly supervised pelvic floor muscle training class and performed daily home exercise for 16 weeks .\n\nLabels: 2\n\nSample: The effect of a sequential estradiol-norethisterone acetate regimen or placebo on lipid metabolism , antioxidative variables and fatty acid composition in serum was measured during the peak-estrogen phase in a randomized , double-blind , placebo-controlled study of 42 healthy postmenopausal women for 3 months .\n\nLabels: 2\n\nSample: Craving was assessed before and after watching the movie .\n\nLabels: 2\n\nSample: The concentration of tacrolimus remained similar between the two groups at 5-8 ng/ml during the initial 6 months , and was significantly decreased at 12 months compared to 6 months ( p < 0.05 ) , along with reduction of oral administration in the long-term group .\n\nLabels: 4\n\nSample: Whether cisplatin-based treatment induces caridiotoxicity in the short term , especially in non-small cell lung cancer ( NSCLC ) patients with cardiovascular comorbidity , has not been studied previously .\n\nLabels: 0\n\nSample: In addition , the ART approach was used for other primary teeth that had no pulpal involvement and no perceived pain before treatment .\n\nLabels: 2\n\nSample: Rates in the STI and control arms for first progression-of-disease event or death were 17.5 and 14.3 , respectively ( hazard ratio = 1.28 ; P = 0.22 ) .\n\nLabels: 4\n\nSample: Blood samples were obtained for creatine kinase ( CK ) and its MB isoform ( CK-MB ) within 36 h.\n\nLabels: 2\n\nSample: Pre-test , post-test and retention test assessments included the use of hand motion analysis and a global rating scale ( GRS ) .\n\nLabels: 2\n\nSample: Eleven ( 37.9 % ) patients treated with olanzapine relapsed compared with 9 ( 29 % ) of those receiving placebo ( chi = 0.53 , df = 1 , p = 0.5 ) .\n\nLabels: 4\n\nSample: The time and quality of anaesthesia and recovery were assessed in two postoperative standardized interviews .\n\nLabels: 2\n\nSample: The two respective nalbuphine solutions were injected into the cephalic vein at a rate of 20 mL/minute ( 0.33 mL/second ) .\n\nLabels: 2\n\nSample: Macroscopic hematuria occurred in eight patients , but there were no differences in complications rates between the three groups .\n\nLabels: 4\n\nSample: Intermittent pneumatic compression ( IPC ) devices prevent lower-extremity deep venous thrombosis ( LEDVT ) when used properly , but compliance remains an issue .\n\nLabels: 3\n\nSample: The whole ETT cuff was dripped either with 3 ml ( 4.5 mg ) of benzydamine hydrochloride or nothing five minutes prior to anesthesia induction .\n\nLabels: 2\n\nSample: Although GCPGC was cleared faster than pegfilgrastim , leading to a 19 % lower systemic exposure to pegylated G-CSF , the increase in ANC and CD34 ( + ) were ~ 20 % greater by GCPGC at 100 g/kg than pegfilgrastim .\n\nLabels: 4\n\nSample: To assess the effect of a comprehensive geriatric assessment and individually tailored intervention on mobility in older people .\n\nLabels: 3\n\nSample: The unanticipated decline in respiratory function immediately following physiotherapy was short-lived and not discernible in longer term outcomes measured by FEV ( 1 ) or physiotherapy requirements post-operatively .\n\nLabels: 1\n\nSample: To evaluate the effectiveness of a cognitive behavioral group-based intervention aimed at reducing depression and fostering quality of life and psychological well-being of multiple sclerosis patients through the promotion of identity redefinition , sense of coherence , and self-efficacy .\n\nLabels: 3\n\nSample: The symptom effects might be mediated by dietary influences on estrogen activity .\n\nLabels: 1\n\nSample: Ultrasonographers uploaded a set of four-chamber views from 10 consecutive screening examinations and a second set 3months later .\n\nLabels: 2\n\nSample: A statistically significant improvement in adherence was found in patients who received biofeedback when compared with those who did not ( 98.8 to 99.8 % [ 95 % CI ] and 95.5 to 97.5 % , respectively [ p < 0.001 ] ) .\n\nLabels: 4\n<Assistant>Understood. I'll keep these facts for future reference.", "[Dialogue between User and Assistant on 2024-01-03 00:00]\n<User>Please study these classification instances and their labels:\n\nSample: No statistically significant favorable effects were seen for garlic or vitamin supplements .\n\nLabels: 4\n\nSample: All patients showed improvements in visual acuity and fluorescein angiographic leakage and had resolution of their neurosensory detachment following treatment .\n\nLabels: 4\n\nSample: Subject variability for d-amphetamine pharmacokinetic parameters was low .\n\nLabels: 1\n\nSample: The time to complete the injections by bevel-up and by bevel-down methods were 165.5 + / - 31.3 and 152.5 + / - 27.4 seconds , respectively ( P < .015 ) .\n\nLabels: 4\n\nSample: The secondary objectives were to evaluate plasma concentrations of PSD503 , BP changes and pulse rate over 3h following administration and to assess safety and tolerability .\n\nLabels: 3\n\nSample: Only minimal adverse effects were experienced .\n\nLabels: 4\n\nSample: Obstruction occurred at a median ( IQR ) of 48 ( 24-60 ) s after the start of PPV .\n\nLabels: 4\n\nSample: We found 19 PMAs in 13 individuals , thus giving a prevalence of 19 % .\n\nLabels: 4\n\nSample: Similar to the lidocaine patch , the lidocaine spray produces cutaneous weak anesthesia at 30 minutes after treatment .\n\nLabels: 1\n\nSample: After 3 and 4 days of twice daily brushing with acid challenges on days 3 and 4 the strontium-based dentifrice demonstrated significantly better dentine occlusion than all other treatments ( p < 0.0001 ) .\n\nLabels: 4\n\nSample: We conducted a randomized study to determine whether any of three chemotherapy regimens was superior to cisplatin and paclitaxel in patients with advanced non-small-cell lung cancer .\n\nLabels: 0\n\nSample: Either methotrexate plus misoprostol or misoprostol alone effectively completed abortion in women with non-viable early pregnancy and represent acceptable medical alternatives to surgery or expectant management .\n\nLabels: 1\n\nSample: We randomly allocated 54 community health officers ( stratified on district and catchment area distance to a health facility : 10 km versus < 10 km ) to intervention ( one injection of oxytocin [ 10 IU ] one minute after birth ) and control ( no provision of prophylactic oxytocin ) arms .\n\nLabels: 4\n\nSample: Postprandial exercise is more effective for improving postprandial lipoprotein metabolism than preprandial exercise .\n\nLabels: 1\n\nSample: Female patients enrolled in a multicenter treatment trial for functional bowel disorders were studied pre - and posttreatment with the IBS-QOL and other health status measures .\n\nLabels: 2\n\nSample: The observed modifications appear to be related to oestrogen depletion per se rather than the degree of oestrogen suppression or the different therapeutic regimen administered .\n\nLabels: 1\n\nSample: A masked observer graded the ocular findings at the initial visit and at the conclusion of the treatment period .\n\nLabels: 2\n\nSample: In addition , wound areas treated with Suprathel required less frequent dressing changes .\n\nLabels: 4\n\nSample: The responses to the study diets differed by sex .\n\nLabels: 4\n\nSample: Lamotrigine and lithium were effective monotherapy for BDII depression , with comparable response and remission rates .\n\nLabels: 1\n\nSample: To examine the effects of a practical method to increase patient completion and filing of advance directives .\n\nLabels: 3\n\nSample: The enrollment began in 2006 .\n\nLabels: 2\n\nSample: A parallel , randomized , multicenter open-label , 1-year study of the OC Seasonale [ 30 microg ethinyl estradiol ( EE ) / 150 microg levonorgestrel ( LNG ) , and Nordette-28 ( 30 microg EE/150 microg LNG ) ] in sexually active , adult women ( 18-40 years ) of childbearing potential .\n\nLabels: 2\n\nSample: Thirty patients with depression were randomised to receive either active or inactive laser treatment .\n\nLabels: 2\n\nSample: Patients carrying the homozygote genotype of rs12768009 ( CYP2C19 8403AA ) , highly linked to rs4244285 ( CYP2C19 * 2 ) , showed a 26.8 % reduced clearance compared with patients with CYP2C19 8403 AG and GG alleles .\n\nLabels: 4\n\nSample: The median age was 48 years ( range , 28 to 76 years ) , median follow-up was 33 months , and median number of chemotherapy cycles in the maintenance group after random assignment was six .\n\nLabels: 4\n\nSample: While the number of patients recruited in this trial was too small to achieve statistically conclusive results , the trend in the results suggests a benefit of oral acyclovir in the treatment of HSV iridocyclitis in patients receiving topical corticosteroids and trifluridine prophylaxis .\n\nLabels: 1\n\nSample: Subjects were tested on a motion platform driven by a simulated ship-motion profile .\n\nLabels: 2\n\nSample: The target day for quitting smoking was usually day 8 .\n\nLabels: 2\n\nSample: In acupuncture and moxibustion group , acupuncture and grain sized moxibustion were given at Zhongwan ( CV 12 ) , Zhangmen ( LV 13 ) , Zusanli ( ST 36 ) , Yinlingquan ( SP 9 ) , Pishu ( BL 20 ) and Weishu ( BL 21 ) ; in medication group , Fluoxetine was orally taken for 20 mg after breakfast .\n\nLabels: 2\n\nSample: Prolonged ( delayed for any cause ) radiation was associated with poorer PFS ( hazard ratio [ HR ] , 1.98 ; 95 % confidence interval [ CI ] , 1.16-3 .38 ; p = 0.012 ) and OS ( HR , 1.88 ; 95 % CI , 1.08-3 .26 ; p = 0.024 ) in GOG 165 but not GOG 120 .\n\nLabels: 4\n\nSample: Additional factors must be weighed before selecting agents for Phase III trials , including safety , tolerability , activity , cost , and availability of these two agents in comparison with other agents currently in development for PD .\n\nLabels: 1\n\nSample: The Aga Khan University Hospital , Karachi in the year 2003-2004 .\n\nLabels: 2\n\nSample: Although this difference in OS is not significant , survival was improved in the randomized letrozole arm over the first 2 years of the study .\n\nLabels: 4\n\nSample: Both treatments demonstrated similar changes on the SF-36 .\n\nLabels: 4\n\nSample: Toxicity rates reported by physicians were always lower than those reported by patients .\n\nLabels: 4\n\nSample: BTDS was efficacious in the treatment of opioid-nave patients with moderate to severe chronic low back pain .\n\nLabels: 1\n\nSample: Seven men and 8 women ( mean age = 55.2 years , SD = 11.3 , range = 43-82 ) performed 3 treadmill tests with random assignment of testing condition : ( 1 ) no body weight support ( BWS ) - standard test , ( 2 ) 0 % BWS-harness in place but no use of external support , and ( 3 ) 15 % BWS-use of external support for 15 % of body mass .\n\nLabels: 2\n\nSample: In an open study , nicotine patches reduced seizures from 1.65 + / - 2.36 to 0.01 + / - 0.0 seizures per day ( p < 0.0001 ) .\n\nLabels: 4\n\nSample: A pragmatic cluster randomized trial in community pharmacies in four Australian states/territories in 2009 .\n\nLabels: 2\n\nSample: This is a prospective randomized open-label study in hypertensive outpatients .\n\nLabels: 2\n\nSample: The investigators and patients were blinded , and outcome was assessed with a verbal scale .\n\nLabels: 2\n\nSample: Comparisons between CG and TG were performed by a Wilcoxon non-parametric test .\n\nLabels: 2\n\nSample: It has been speculated about the potential influence of vigorous physical activity on modifying the age of onset of adiposity rebound .\n\nLabels: 0\n\nSample: Daily impact loading was assessed by using an accelerometer .\n\nLabels: 2\n\nSample: Most parents ( 90 % ) believed that male HPV vaccination was generally important .\n\nLabels: 4\n\nSample: Both groups reported significant improvements in HIV/STI/condom knowledge immediately following the intervention , compared to controls .\n\nLabels: 4\n\nSample: Three types of recruitment challenges not related to patients were identified and met during the trial : 1 ) organizational challenges , 2 ) challenges with finding eligible participants and 3 ) challenges with having professionals invite patients to participate .\n\nLabels: 4\n\nSample: The change from baseline at each treatment cycle was compared between groups using a weighted analysis of covariance model .\n\nLabels: 2\n\nSample: We assessed if serologic evidence of infection with H. pylori is associated with increased serum C-reactive protein ( CRP ) levels .\n\nLabels: 0\n\nSample: There were no statistical differences between the two arms for the primary outcome of DFS ( hazard ratio [ HR ] 0.91 , 95 % confidence interval [ CI ] 0.73-1 .15 ) or the secondary outcomes of DMFS ( HR 1.02 , 95 % CI 0.80-1 .32 ) and OS ( HR 1.09 , 95 % CI 0.82-1 .45 ) .\n\nLabels: 4\n<Assistant>I've captured all of this valuable information.", "[Dialogue between User and Assistant on 2024-01-04 00:00]\n<User>Please learn from these labeled classification instances:\n\nSample: In addition , the majority of subjects found FT easier to use ( 64 % [ 144/226 ] ) , easier to inject the insulin dose ( 65 % [ 148/227 ] ) and easier to push for injection ( 69 % [ 155/226 ] ) .\n\nLabels: 4\n\nSample: Our goals were to compare cognitive , language , behavioral , and educational outcomes of preterm children to term controls and to evaluate the impact of neonatal brain injury , indomethacin , and environmental risk factors on intellectual function at 12 years of age .\n\nLabels: 3\n\nSample: There were 27 control patients , 30 exercise patients , and 8 patients that had balance physiotherapy .\n\nLabels: 2\n\nSample: 21 general hospitals and three academic centres in the Netherlands .\n\nLabels: 2\n\nSample: Between February 2003 and December 2005 , a total of 63 out of 67 Swedish patients were analyzed : BKP ( n = 32 ) and control ( n = 31 ) .\n\nLabels: 4\n\nSample: Forty-six ASA I-II patients undergoing strabismus surgery with intraoperative awakening were randomly assigned to anesthesia by TCI of propofol + sufentanil group ( group SF ) or propofol + remifentanil spontaneous breathing .\n\nLabels: 2\n\nSample: This study investigates if MHFA training in a Swedish context provides a sustained improvement in knowledge about mental disorders , a better ability to be helpful in contacts with people who are ill and if it changes attitudes in a positive direction .\n\nLabels: 0\n\nSample: Patients in the collaborative-care arm with recognized depression will be offered a choice of evidence-based low-intensity psychological treatments based on cognitive and behavioral approaches .\n\nLabels: 2\n\nSample: Patients were divided into two groups of A ( treatment ) and B ( control ) .\n\nLabels: 2\n\nSample: Methadone is a drug of indisputable value in the treatment of cancer pain , and an unbalanced focus on the risks of inappropriate use rather than the benefits should not compromise the use of a relevant alternative to morphine in the management of cancer pain .\n\nLabels: 1\n\nSample: The primary outcome measure is the mean Sequential Organ Failure Assessment ( SOFA ) score while in the ICU .\n\nLabels: 2\n\nSample: An analysis of the surgeon as a factor on the functional outcome ( logMAR visual acuity ) , primary anatomic success ( retinal reattachment central to the aequator without any additional retina-affecting surgery including laser , cryo and macular pucker surgery ) and final anatomic success ( retinal reattachment one year postoperatively ) was carried out .\n\nLabels: 2\n\nSample: To determine whether a home-based exercise program is able to increase functional capacity ( FC ) and reduce heart rate variability ( HRV ) in postmenopausal women with coronary heart disease .\n\nLabels: 3\n\nSample: The most important risk factor for treatment failure was non-compliance , which was also associated with longer duration of therapy .\n\nLabels: 1\n\nSample: Major postoperative thrombotic events , as a potential consequence of antifibrinolytic treatment , were recorded .\n\nLabels: 2\n\nSample: The patients were randomly assigned to two groups , 60 in group A received TVT-O alone , while 60 in group B not only received TVT-O but also received biofeedback pelvic floor electrical stimulation .\n\nLabels: 2\n\nSample: one of piroxicam group was resigned , so that there was 19 person left to complete this study .\n\nLabels: 4\n\nSample: Twenty patients undergoing elective coronary bypass grafting were included in this randomized double-blind study .\n\nLabels: 2\n\nSample: ATD was associated with significantly lower attractiveness ratings for happy faces and attenuation of intensity/arousal ratings of angry faces .\n\nLabels: 4\n\nSample: Of 343 individuals enrolled , 49 received firategrast 150 mg , 95 received firategrast 600 mg , 100 received firategrast 900 mg or 1200 mg , and 99 received placebo .\n\nLabels: 4\n\nSample: Both dosages proved to be highly immunogenic , producing high seroconversion and seroprotection rates and geometric mean anti-HBs concentrations after 3 doses .\n\nLabels: 4\n\nSample: The combination group showed lower visual analogue scale scores than those of patients receiving either drug alone , both at rest and on coughing .\n\nLabels: 4\n\nSample: Although between 3 % and 16 % of women undergoing hysterectomy reported adverse changes in psychosocial well-being after surgery , similar percentages of women in the control groups reported such effects .\n\nLabels: 4\n\nSample: Upward orientation of the epidural needle bevel further improved the success rate to 96 % and 91 % for CSE-Q and CSE-S kits , respectively .\n\nLabels: 4\n\nSample: Plasma repaglinide and blood glucose concentrations were measured up to 7 hours .\n\nLabels: 2\n<Assistant>Thanks for letting me know. I'll keep track of this.", "[Dialogue between User and Assistant on 2024-01-05 00:00]\n<User>Here are some classification examples to learn from. Please pay attention to the labels:\n\nSample: Systolic arterial pressure was higher in the ketamine group 20 min after administration of the drug and upon arrival in the operating theater .\n\nLabels: 4\n\nSample: The primary outcome measure was change in BPRS total score from baseline .\n\nLabels: 2\n\nSample: Some forms of chronic pain are receptive to exercise therapy for maintenance of pain relief .\n\nLabels: 3\n\nSample: In group 1 , standard repair was performed ; in group 2 , microfractures of the greater tuberosity were performed to enhance tendon repair .\n\nLabels: 2\n\nSample: Intermittent transdermal NTG therapy is recommended to avoid the development of tolerance .\n\nLabels: 0\n\nSample: They were monitored for 12 weeks .\n\nLabels: 2\n\nSample: The scores of clinical symptoms of Chinese medicine decreased in both groups , which showed statistical significances compared with those before treatment ( P < 0.01 , P < 0.05 ) .\n\nLabels: 4\n\nSample: Analysis limited to those patients who accomplished a high attendance rate ( > 67 % ) showed similar results .\n\nLabels: 4\n\nSample: The present report includes analyses of secondary efficacy variables from this 12-week trial .\n\nLabels: 2\n\nSample: The remaining 45 implants were stable at every subsequent follow-up examination , and 6 months after implant placement , ISQ values were measured .\n\nLabels: 4\n\nSample: The uncertainty about optimum strategies and cost effectiveness have retarded widespread acceptance .\n\nLabels: 0\n\nSample: Smoking , but not alcohol consumption , was associated with an increased risk of thyroid enlargement in women ( OR = 3.94 , 95 % CI = 1.64-9 .48 ) .\n\nLabels: 4\n\nSample: The primary tolerability end point was treatment discontinuation .\n\nLabels: 2\n\nSample: Paracetamol is ineffective for decreasing the pain from heel prick in term neonates .\n\nLabels: 1\n\nSample: The internal consistency of the KAQ was 0.61 and its responsiveness , measured using change scores of knowledge before and after an educational intervention , was 0.75 .\n\nLabels: 4\n\nSample: Control participants ( n = 9 ) received 10 hr TIB on all study nights .\n\nLabels: 2\n\nSample: Most cardiac operations with cardiopulmonary bypass ( CPB ) are conducted with high oxygen partial pressure .\n\nLabels: 0\n\nSample: The primary endpoint was the percentage change from baseline in FEV ( 1 ) .\n\nLabels: 3\n\nSample: The tailoring + video-coaching participants will receive a computer-tailored web-based physical activity intervention ( ` My Activity Coach ' ) with brief coaching sessions with a physical activity expert over an online video calling program ( e.g. Skype ) .\n\nLabels: 2\n\nSample: The endpoints were times to virologic failure , safety event and regimen modification .\n\nLabels: 2\n\nSample: It was not possible to describe the data using a model without tolerance .\n\nLabels: 4\n\nSample: A decided advantage of ketorolac over fentanyl is the absence of nausea and vomiting in the intraoperative and postoperative periods .\n\nLabels: 1\n\nSample: Treatment period was 336 hours in subarachnoid hemorrhage patients and 168 hours in patients with complicated stroke or intracerebral hemorrhage patients .\n\nLabels: 2\n\nSample: At the end of the study period , we could find no significant difference between the two groups regarding haemorrhage , number of recurrences or complications .\n\nLabels: 4\n\nSample: The study enrolled 400 patients ( 400 eyes ) .\n\nLabels: 4\n\nSample: Patients assigned to fluoxetine attended more physician visits , exhibited a greater reduction in binge eating and vomiting , and had a greater improvement in psychological symptoms than those assigned to placebo .\n\nLabels: 4\n\nSample: Days with migraine were fewer by at least 50 % in 14 participants for active treatment versus placebo .\n\nLabels: 4\n\nSample: The chest function was measured using an electronic spirometer to determine the vital capacity ( VC ) , tidal volume ( TV ) , inspiratory reserve volume ( IRV ) , expiratory reserve volume , forced vital capacity ( FVC ) , forced expiratory volume ( FEV ) , FEV in 1-second ( FEV ) and the ratio of FEV to FVC ( FEV % ) .\n\nLabels: 2\n\nSample: In addition , little is known about how to handle sensitized patients with low levels of sensitization .\n\nLabels: 0\n\nSample: The lack of association between impedance baseline and heartburn severity indicates that other factors may contribute to heartburn perception in GERD .\n\nLabels: 1\n\nSample: The control group consisted of 10 , 42 and 53 cases , respectively , in which the Doppler results were not revealed .\n\nLabels: 2\n\nSample: With the use of either fostamatinib regimen in patients with RA , statistically significant , but not clinically significant , improvements in the ACR20 improvement response over placebo were achieved at 24 weeks , whereas a significant difference in the SHS was not seen .\n\nLabels: 1\n\nSample: Twenty-seven patients of septic shock with myocardial depression were divided into routine group ( 14 cases , level of blood glucose was 4.1 to 6.1 mmol/L ) and target group ( 13 cases , level of blood glucose was 6.2 to 8.3 mmol/L ) .\n\nLabels: 2\n\nSample: Many surgical patients are dependent on nicotine .\n\nLabels: 0\n\nSample: Nine patients received dentures made of conventional heat-cured acrylic resin , and eight patients received dentures made of rapid heat-cured acrylic resin .\n\nLabels: 2\n\nSample: AEs were typically characterized as mild and included infections , skin disorders , and dizziness .\n\nLabels: 4\n\nSample: Guidewire position was measured in the coronal and sagittal planes .\n\nLabels: 2\n\nSample: There were two toxicity-related lower extremity amputations in the melphalan-plus-TNF-alpha arm , and one disease progression-related upper extremity amputation in the melphalan-alone arm .\n\nLabels: 4\n\nSample: Biofeedback also produced greater reductions in straining , sensations of incomplete evacuation and anorectal blockage , use of enemas and suppositories , and abdominal pain ( all P < .01 ) .\n\nLabels: 4\n\nSample: No statistically significant difference was found between low vs. high dysplastic patients and between patients with sagittal contour realignment vs. patients with additional anterior slippage reduction ( p > 0.05 ) .\n\nLabels: 4\n\nSample: A randomized placebo controlled cross-over trial .\n\nLabels: 2\n\nSample: We used the emotional Stroop test and an implicit memory test to investigate whether alcohol hinders appraisal of social threat words in patients diagnosed with social phobia .\n\nLabels: 0\n\nSample: Humidity , temperature , HDM counts ( trap and vacuum samples ) , HDM allergen , and other details of the home environment were measured on four occasions over a period of 1 year .\n\nLabels: 2\n\nSample: Participants with traumatic complete SCI between C5 motor and T11 neurological levels who could receive macrophage therapy within 14 days of injury were randomly assigned in a 2:1 ratio to the treatment ( autologous incubated macrophages ) or control ( standard of care ) groups .\n\nLabels: 2\n\nSample: The efficacy of both treatments declined with increasing time since unprotected coitus ( p = 0.01 ) .\n\nLabels: 4\n\nSample: Decisions to upgrade were influenced by predictors of benefit in subgroup analyses of the RAFT study and other trials .\n\nLabels: 1\n\nSample: Patient anxiety and satisfaction can be affected by the consent document .\n\nLabels: 1\n\nSample: The efficacy of second-line platinum-based chemotherapy followed at progression by gefitinib was similar to first-line platinum-based chemotherapy , and epidermal growth factor receptor mutation types did not influence the efficacy of second-line platinum-based chemotherapy .\n\nLabels: 1\n\nSample: Further research is needed to study the long-term outcomes of TIW treatment .\n\nLabels: 1\n\nSample: PCP occurred most frequently with the daily 1-mg/kg regimen ( 22.0 cases/100 patient years ) , least frequently with the daily 2-mg/kg regimen ( 0 case/100 patient years ) and at intermediate frequency with the weekly regimen ( 9.5 cases/100 patient years ) .\n\nLabels: 4\n\nSample: Each treatment strategy resulted in a significant reduction in all exercise-induced variables of myocardial ischemia measured at 12 weeks .\n\nLabels: 4\n\nSample: Community clinical trial with randomised allocation .\n\nLabels: 2\n\nSample: A phase III , multicenter randomized controlled trial was conducted .\n\nLabels: 2\n\nSample: Psychotherapy outcome research : Methods for reporting variability and evaluating clinical significance .\n\nLabels: 2\n\nSample: To compare remifentanil , alfentanil and fentanyl in providing analgesia for retrobulbar block injection .\n\nLabels: 3\n\nSample: Mean LMA intracuff pressure was less in the pressure-limiting group versus the routine care group ( 40 + / - 6 vs. 114 + / - 57 mmHg , P < 0.001 ) .\n\nLabels: 4\n\nSample: Data supporting the effectiveness of platelets that are compatible according to cross-matching with a modified antigen capture enzyme-linked immunosorbent assay ( MAC-ELISA or MACE ) are limited .\n\nLabels: 0\n\nSample: Thyroidectomy can be performed under local anesthesia with monitored anesthesia care ( MAC ) with results similar to general anesthesia in an outpatient or inpatient surgery setting .\n\nLabels: 3\n\nSample: Continuous infusion of propofol for ERCP by direction of gastroenterologist yields no difference in the completion rate and adverse profiles when compared with conventional technique but it provides a better recovery profile .\n\nLabels: 1\n\nSample: The stratified randomized sample included 70 primary caregivers of children with HIV/AIDS .\n\nLabels: 2\n<Assistant>I've captured all of this valuable information.", "[Dialogue between User and Assistant on 2024-01-06 00:00]\n<User>The following are classification examples with their corresponding labels:\n\nSample: Here , we report the impact of OLAT on the outcome of patients with invasive aspergillosis .\n\nLabels: 0\n\nSample: 4,016 patients with blood pressure ( BP ) < 160/100 mm Hg who had been treated with an ACEI for > 3 months were enrolled .\n\nLabels: 2\n\nSample: Sixty patients were included into a prospective randomized trial to determine the influence of laparoscopic ( n = 30 ) or conventional ( n = 30 ) resection of colorectal tumors on postoperative pain and fatigue .\n\nLabels: 2\n\nSample: Repeated-measures design with 2 independent variables : group ( exercise and nonexercise control ) and time ( preexercise and 12 and 36 h postexercise ) .\n\nLabels: 2\n\nSample: Both groups showed progressive weight loss .\n\nLabels: 4\n\nSample: Patients received either ciprofloxacin 0.3 % / dexamethasone 0.1 % otic suspension 4 drops twice daily for 7 days or ofloxacin 0.3 % otic solution 5 drops twice daily for 10 days .\n\nLabels: 2\n\nSample: The predictive value of MRI for subsequent neurological impairment is not affected by therapeutic hypothermia .\n\nLabels: 1\n\nSample: Cigarette packaging is a key marketing strategy for promoting brand image .\n\nLabels: 0\n\nSample: A single dose of intramuscular betamethasone 12 mg was safe and as efficacious as prednisone in preventing the relapse of acute asthma .\n\nLabels: 1\n\nSample: Following intervention attentional biases of women who received CBT increased becoming comparable to non-depressed women .\n\nLabels: 4\n\nSample: Under fasting conditions total and maximum exposure , represented by geometric mean AUC ( 0-tlast ) - and C ( max ) - values , respectively were 466.7 h * ng/ml ( AUC ( 0-tlast ) ) and 21.9 ng/ml ( C ( max ) ) for Test and 507.8 h * ng/ml ( AUC ( 0-tlast ) ) and 22.0 ng/ml ( C ( max ) ) for Reference tablets .\n\nLabels: 4\n\nSample: Stroke occurred in 23 patients in the dronedarone group and 10 in the placebo group ( hazard ratio , 2.32 ; 95 % CI , 1.11 to 4.88 ; P = 0.02 ) .\n\nLabels: 4\n\nSample: The primary goal of tocolytic therapy is to reduce neonatal morbidity and mortality .\n\nLabels: 3\n\nSample: Women highly accept the non-RhD antibody screening program .\n\nLabels: 1\n\nSample: The primary outcome measure was change in pain intensity ( baseline vs. posttreatment average pain ) using a 0 to 100 mm Visual Analog Scale .\n\nLabels: 2\n\nSample: Birth certificate records were used to obtain additional information .\n\nLabels: 2\n\nSample: There was no statistical difference in the levels of S1001 and NSE between the two groups at T1 ( P > 0.05 ) .\n\nLabels: 4\n\nSample: Between-group differences were not significant for RMDQ or any secondary outcomes ( e.g. , pain ) at any time .\n\nLabels: 4\n\nSample: There was a within-group x time interaction for the ADLS , global rating of knee function , and crossover hop test scores .\n\nLabels: 4\n\nSample: Forty-one NYHA III to IV heart failure patients were divided into rapid and slow acetylators by population kinetic modeling .\n\nLabels: 2\n\nSample: Epithelial cells in the postoestrus group had higher cell area , cytoplasm area , cell diameter and cell perimeter measurements ( P < 0.01 ) .\n\nLabels: 4\n\nSample: A fifth course is unnecessary .\n\nLabels: 1\n\nSample: The change in ghrelin was inversely correlated with the change in body weight , body mass index , fat-free mass , and energy availability .\n\nLabels: 4\n\nSample: Also cervical gaps appeared to have no relation with the failure rate ( p = 0.057 at t = 1 and p = 0.833 at t = 2 ) However , together those variables have a significant influence on the survival rate ( p = 0.025 ) .\n\nLabels: 4\n\nSample: Baseline and 5-year follow-up renal structural variables were assessed by masked electron microscopic morphometric analyses from percutaneous renal biopsy specimens .\n\nLabels: 2\n\nSample: To compare the ACSM-CDC physical activity accumulation recommendation to the traditional recommendation , for impact on mood and physiological markers of fitness .\n\nLabels: 0\n\nSample: The Main Outcome Measure is the cumulative use of morphine within the first 48 hours after surgery ( measured by patient controlled analgesia PCA ) .\n\nLabels: 2\n\nSample: A prospective , blinded , parallel-group multi-center trial ( 2 sites ) , with balanced randomization [ 1:1 ] .\n\nLabels: 2\n\nSample: Early surgery or an intended six months of continued conservative treatment , with delayed surgery if needed .\n\nLabels: 2\n\nSample: To evaluate the therapeutic value of transcutaneous electrical nerve stimulation ( TENS ) at acupoints in slow transit constipation ( STC ) .\n\nLabels: 3\n\nSample: Of the 153 study patients , 79 were randomized to the 3-day bag change regimen , and 74 patients were in the no-change group .\n\nLabels: 4\n\nSample: The precision of variables to differentiate rofecoxib from placebo was evaluated using effect size ( i.e. , mean difference between rofecoxib versus placebo divided by pooled SD ) .\n\nLabels: 2\n\nSample: Patient satisfaction with esthetics , root sensitivity , and postoperative pain was also evaluated .\n\nLabels: 2\n\nSample: Treatment of psoriatic nail is difficult .\n\nLabels: 0\n\nSample: To affirm these previous findings through more objective , quantitative methodology , we now report data from a subset analysis of refractory partial epilepsy patients in the study who underwent Goldmann kinetic perimetry .\n\nLabels: 3\n\nSample: Findings indicated dissimilarities between subjective and objective measures of hot flashes .\n\nLabels: 1\n\nSample: Primary care in the Netherlands .\n\nLabels: 2\n\nSample: Correlation coefficients were calculated for each of these surrogates with proposed formulas for insulin sensitivity found in the literature .\n\nLabels: 2\n\nSample: The sensitivity was 98.2 % in the GA group ( confidence interval , 97-100 % ) and 98.1 % in the MS group ( confidence interval , 97-100 % ) ( P = 0.979 ) .\n\nLabels: 4\n\nSample: Median FSH serum levels were suppressed in both groups , but such suppression was lower among patients receiving letrozole , who showed significantly higher median FSH serum levels ( P < .0001 ) .\n\nLabels: 4\n\nSample: Dorzolamide caused a more bitter taste ( P = 0.01 ) than brimonidine purite .\n\nLabels: 4\n\nSample: Dietary intake was assessed via the Block Food Frequency Questionnaire at baseline and 8 weeks .\n\nLabels: 2\n<Assistant>Thanks for the update. I've recorded these facts.", "[Dialogue between User and Assistant on 2024-01-07 00:00]\n<User>Here are categorized examples with their respective labels:\n\nSample: Routine immediate PTCA does not confer additional benefit .\n\nLabels: 1\n\nSample: Episodes of mean arterial pressure ( MAP ) more than 100 mm Hg or less than 60 mm Hg for more than 1 min were defined as hypertensive or hypotensive events , respectively .\n\nLabels: 2\n\nSample: Fasting plasma glucose , postprandial plasma glucose ( PPG ) , glycated hemoglobin , serum triglycerides ( TG ) , total cholesterol , low-density lipoprotein cholesterol and high-density lipoprotein cholesterol ( HDL-C ) were determined before and after pioglitazone treatment .\n\nLabels: 2\n\nSample: Treatment options for wild-type BRAF melanoma patients remain limited .\n\nLabels: 0\n\nSample: Subjective knee function was better in the patients in the metal screw group ; they had less pain at rest , a higher Tegner score , a higher Lysholm score , and better subjective knee function at 2 years compared to the bioabsorbable screw group .\n\nLabels: 4\n\nSample: At Time 4 monitors and blunters in each of the treatment groups reported a significant decrease in A-state anxiety .\n\nLabels: 4\n\nSample: Risk of treatment failure with chloroquine + sulfadoxine-pyrimethamine was unacceptably high .\n\nLabels: 1\n\nSample: The primary efficacy variable ( over weeks 1-4 ) was the response to the question : `` Over the past week do you consider that you have had satisfactory relief from your IBS symptoms ? ''\n\nLabels: 2\n\nSample: Subjects received a 14-day course of either 4 x/day therapy of CBS ( 108 mg ) , tetracycline HCl ( 500 mg ) , and metronidazole ( 250 mg ) , or 5 x/day therapy of CBS ( 108 mg ) , tetracycline HCl ( 250 mg ) , and metronidazole ( 200 mg ) .\n\nLabels: 2\n\nSample: We studied 70 patients with esophageal cancer who were scheduled to undergo esophagectomy .\n\nLabels: 2\n\nSample: Subjects in this follow-up dismantling report were 96 children aged 2-10 who were part of the original study and who underwent anaesthesia and surgery .\n\nLabels: 2\n\nSample: Predictors of poor outcomes include the presence of significant pre - and postoperative pain .\n\nLabels: 0\n\nSample: A randomized clinical trial .\n\nLabels: 2\n\nSample: This was mediated by fewer infections , accelerated recovery from organ failure and reduced duration of hospitalization .\n\nLabels: 0\n\nSample: The questionnaire also showed that the CBT group had increased their knowledge and awareness about oral health .\n\nLabels: 4\n\nSample: Each participant performed intubation with each device while wearing standard uniform and CBRN-PPE .\n\nLabels: 2\n\nSample: At baseline , participants ( mean age , 51.1 years ; 45.0 % women ) smoked an average of 20 cigarettes per day with a median duration of 32 years .\n\nLabels: 4\n\nSample: There is growing evidence from experimental studies that the acupuncture dose or technique influences the speed of onset of hypoalgesia .\n\nLabels: 3\n\nSample: All patients were from one academic setting and all trial visits were conducted in usual clinical care .\n\nLabels: 2\n\nSample: Primary outcome measures are gestational weight gain , fasting glucose and insulin sensitivity , with a range of obstetric secondary outcome measures including birth weight .\n\nLabels: 2\n\nSample: Participant satisfaction with the course was high , and feedback highlighted that patients enjoyed the group format .\n\nLabels: 4\n\nSample: Prospective , randomized , placebo-controlled study ( Canadian Task Force classification I ) .\n\nLabels: 2\n\nSample: 117 patients with CIDP who met specific neurophysiological inflammatory neuropathy cause and treatment ( INCAT ) criteria participated in a randomised , double-blind , placebo-controlled , response-conditional crossover trial .\n\nLabels: 2\n\nSample: After the release of IMF , they were started on jaw exercises with the aid of wooden spatulae to overcome trismus due to muscle spasm .\n\nLabels: 2\n\nSample: In the 12-hour group , MgSO4 treatment was extended in seven women ( 6.9 % ) for progression to severe disease versus one ( 1.1 % ) in the 24-hour group ( P = .07 ) .\n\nLabels: 4\n\nSample: None of the dogs exhibited any clinical or neurologic abnormalities during the study .\n\nLabels: 4\n\nSample: Either sarpogrelate or ticlopidine was administered for at least 4 weeks after the procedure .\n\nLabels: 2\n\nSample: The study population was then divided into two subgroups of 129 and 114 patients by random allocation using computer generated numbers .\n\nLabels: 2\n\nSample: Control of diabetes was revaluated at three months post-treatment period .\n\nLabels: 2\n\nSample: However , the advantage of Volumatic is of marginal clinical relevance since the additional bronchodilation was a maximum of 140 ml FEV ( 1 ) and did not exceed the minimal patient-perceivable improvement .\n\nLabels: 4\n<Assistant>Thank you for sharing. I've noted this information.", "[Dialogue between User and Assistant on 2024-01-08 00:00]\n<User>Please observe these classification examples and their associated labels:\n\nSample: The measurement of blood pressure ( BP ) at home by patients with hypertension is increasingly used to assess and monitor BP .\n\nLabels: 0\n\nSample: Two patients in each group received treatment for endometritis .\n\nLabels: 4\n\nSample: At 5 minutes , 33 of 74 ( 44.6 % ) patients from the midazolam group were adequately sedated compared with 13 of 79 ( 16.5 % ) patients from the droperidol group , a difference of 28.1 % ( 95 % CI 12.9 % to 43.4 % ; P < .001 ) .\n\nLabels: 4\n\nSample: Therefore , we attempted controlled randomized study in order to compare classic appendectomy with laparoscopic appendectomy and confirm eventual advantages of caring base of appendix with hem-o-lok clips regarding ordinary accepted endoloop method during laparoscopic appendectomy .\n\nLabels: 0\n\nSample: The main impact of the intervention was through direct contact and motivating telephone calls to patients .\n\nLabels: 1\n\nSample: To test the causal relationship between sex hormones and cognitive skills in postmenopausal women .\n\nLabels: 3\n\nSample: Each year , two individualized counseling sessions were organized to the intervention families .\n\nLabels: 4\n\nSample: Four hundred and thirty consecutive adult patients with SAB were prospectively followed up for 3 months .\n\nLabels: 2\n\nSample: Mortality was similar between the two treatment groups .\n\nLabels: 4\n\nSample: For the total cohort ( N = 1022 ) , treatment with TRH was associated with motor delay ( odds ratio [ OR ] , 1.51 ; 95 % confidence interval [ CI ] 1.11 to 2.05 ) ; social delay ( OR 1.40 ; 95 % CI 1.01 to 1.95 ) ; sensory impairment ( OR , 2.00 ; 95 % CI 1.06 to 3.74 ) ; severe impairment ( OR , 1.75 ; 95 % CI 1.07 to 2.87 ) ; and a trend toward motor impairment ( OR , 1.50 ; 95 % CI .97 to 2.33 ) , early language impairment ( OR , 1.27 , 95 % CI .90 to 1.79 ) , and fine motor delay ( OR , 1.15 ; 95 % CI .83 to 1.60 ) .\n\nLabels: 4\n\nSample: The main efficacy parameter ( end-point ) was the proportion of patients who achieved complete disappearance of erythema and scaling ( treatment responders ) at the end of the initial phase ( 28 days or less ) and of the maintenance phase ( 28 days ) .\n\nLabels: 2\n\nSample: Breastfed infants showed greater liking of peaches , as did their mothers , who ate more fruits in general than did mothers who formula fed .\n\nLabels: 4\n\nSample: Adequate zinc is critical for immune function ; however , zinc deficiency occurs in > 50 % of human immunodeficiency virus ( HIV ) - infected adults .\n\nLabels: 0\n\nSample: These data indicate an important effect of underlying cardiac rhythm on the awake haemodynamic effects of NCPAP in patients with CHF .\n\nLabels: 1\n\nSample: Aliskiren/HCT single-pill combination treatment showed similar tolerability to aliskiren monotherapy .\n\nLabels: 4\n\nSample: No significant adverse events were reported and no virological failures occurred during the study .\n\nLabels: 4\n\nSample: Within the context of a broader cultural recognition of the protective function of parent involvement in the lives of adolescents , the findings of this study reinforce the potential value of a parent-adolescent partnership in managing chronic disease .\n\nLabels: 1\n\nSample: At the final analysis ( January , 2014 ) , median follow-up was 234 months ( IQR 156-296 ) for patients in the dacomitinib group and 244 months ( 115-389 ) for those in the placebo group .\n\nLabels: 4\n\nSample: This change was more prominent with RF than with other treatments in parallel with its greater hypotriglyceridemic capacity ( p < 0.05 compared with R and R ) .\n\nLabels: 4\n\nSample: A follow-up visit was scheduled 3 months after the end of therapy or participation in the control group .\n\nLabels: 2\n\nSample: Although the two drugs displayed similar efficacy in the resolution of acne lesions at 12 weeks , a significantly greater reduction in the number of comedones was seen at week 4 among patients treated with tretinoin gel microsphere ( p = 0.047 ) .\n\nLabels: 4\n\nSample: The clinical relevance is unclear .\n\nLabels: 1\n\nSample: Patients were randomized to receive either IN albuterol ( 0.15 mg/kg/dose every 30 min ) or CN albuterol ( 0.3 mg/kg/hr ) for a maximum of 2 hours .\n\nLabels: 2\n\nSample: The primary effectiveness endpoint was the proportion of patients who maintained pain control [ change from baseline in mean pain intensity ( 11-point numerical rating scale ) less than +1.5 for 3 consecutive days and no more than two doses of rescue medication per day for 3 consecutive days ) during the first week of open-label treatment .\n\nLabels: 2\n\nSample: The item fatigue showed substantial overlap with fitness and was therefore excluded .\n\nLabels: 2\n\nSample: The study revealed that the maximum extent of acute radiation side effects was reduced in the enzyme group : skin reactions ( mean : 0.97 vs 1.68 in the control group , P < 0.001 ) , vaginal mucosal reactions ( 0.55 vs 0.85 , P = 0.10 ) , genitourinary symptoms ( 0.93 vs 1.38 , P < 0.001 ) and gastrointestinal reactions ( 1.12 vs 1.30 , P = 0.12 ) .\n\nLabels: 4\n\nSample: There were significant improvements over time on most dimensions of health-related quality of life in both the intervention and control group to US norm population levels on most SF-36 dimensions and summary scores .\n\nLabels: 4\n\nSample: This is the first pharmacological investigation demonstrating the usefulness of a TVA task for high-resolution and repeated cognitive parameter estimation after cognitive-enhancing medication .\n\nLabels: 1\n\nSample: Data were analyzed using repeated measures mixed effects models ( MEMs ) that allow the inclusion of initial differences and uncompleted repeated measures , with the assumption of data missing at random .\n\nLabels: 2\n\nSample: Our findings , in keeping with other reports on COX-2 inhibitors , indicated that the inhibition of a COX-2 with a moderate dose of a selective COX-2 inhibitor did not induce clinically sufficient regression of adenomas in patients with FAP in a limited ( 6-month ) medication period .\n\nLabels: 1\n\nSample: Women with imminent delivery before 34.0 gestational weeks were eligible if they remained undelivered for > 7 days after a single course of antenatal BM .\n\nLabels: 2\n\nSample: For instance , CGI-I ratings of ` very much improved ' were linked to SANS percent changes of -90 to -67 , ` much improved ' to -50 to -42 , and ` minimally improved ' to -21 to -13 .\n\nLabels: 4\n<Assistant>Thank you for sharing. I've noted this information.", "[Dialogue between User and Assistant on 2024-01-09 00:00]\n<User>Please memorize these classification examples and their labels:\n\nSample: Group 1 was instructed to self-weigh at the same time once per day and group 2 was instructed to self-weigh immediately after waking up in the morning and immediately before going to bed every day for twelve weeks .\n\nLabels: 2\n\nSample: Flow cytometry was used to detect CD4 + ( T-helper ) and CD8 + cells ( T-suppressor ) with monoclonal antibodies .\n\nLabels: 2\n\nSample: A cross-sectional study involving a random representative sample of 2270 adults from southern Spain ( Malaga ) was undertaken .\n\nLabels: 2\n\nSample: Stone size has been identified as an important predictive factor for stone expulsion .\n\nLabels: 1\n\nSample: Our study enrolled 60 constipated female health worker volunteers .\n\nLabels: 2\n\nSample: Prenatal magnesium sulfate may reduce the risk of cerebral palsy or death in very preterm infants .\n\nLabels: 0\n\nSample: No difference was statistically significant .\n\nLabels: 4\n\nSample: The protocol included 4 experiments for each participant that were carried out in randomised order and comprised : GLP-1 infusion at a rate of 1 pmol/kg/min for 4h , GIP at a rate of 2 pmol/kg/min , GLP-1 + GIP and placebo infusion .\n\nLabels: 2\n\nSample: MEST patients received 30-minute MEST sessions twice daily for 7 to 14 days .\n\nLabels: 2\n\nSample: This is a randomised controlled trial comparing revascularisation or not , in addition to optimal medical therapy with ACE inhibitors , beta-blockers , aldosterone antagonists and an anti-thrombotic agent .\n\nLabels: 2\n\nSample: Our main outcomes were success or failure of airway and time to airway .\n\nLabels: 2\n\nSample: Outcome measures included disease-specific quality of life ( Anterior Cruciate Ligament-Quality of Life [ ACL-QOL ] Questionnaire ) , anterior tibial translation ( KT-1000 arthrometer side-to-side difference ) , the single-limb forward hop test ( limb symmetry index ) , and Tegner Activity Scale .\n\nLabels: 2\n\nSample: All patients had a tumor localised < or = 10 cm from the anal verge and a circumferential margin < or = 5 mm on a magnetic resonance scan .\n\nLabels: 2\n\nSample: Ondansetron administration reduces the need for sedation during TEE and improves patient comfort .\n\nLabels: 1\n\nSample: Although recommendations by the Advisory Committee on Immunization Practices included children who were 6 to 23 months of age at any point during the influenza season , our practices chose not to recall children 22 to 23 months of age , because they would have become > 24 months of age during the study period .\n\nLabels: 2\n\nSample: Also , there was a significant decrease in serum levels of B-type natriuretic peptide .\n\nLabels: 4\n\nSample: Histological evaluation demonstrated more intense tissue neoformation in the glue groups , particularly in the Coseal group .\n\nLabels: 1\n\nSample: Further study is needed to examine the clinical importance of gums and cross-reactive food antibodies in symptomatic individuals .\n\nLabels: 1\n\nSample: Blood loss during operation influenced the prognosis .\n\nLabels: 4\n\nSample: After propensity-score matching ( for risk adjustment ) , use of standard admission orders was not associated with significantly lower 30-day or 1-year mortality .\n\nLabels: 4\n\nSample: Leukotriene B ( 4 ) was not found in any sample and cysteinyl-leukotriene was not found in condensates collected with R-Tube or Anacon .\n\nLabels: 4\n\nSample: Supplemental oxygen is often given routinely to all patients suffering from an acute stroke , although clinical evidence for its efficacy is not available .\n\nLabels: 0\n\nSample: Median age and time from Fontan completion were 15 ( interquartile range [ IQR ] 11.7-18 .2 ) and 11.9 years ( IQR 9.0-15 .7 ) , respectively .\n\nLabels: 4\n\nSample: Simultaneously , a continuous intravenous infusion of C-leucine and H-phenylalanine ( both 9 mol kg h ) was performed .\n\nLabels: 2\n\nSample: The ranking of SR values ( Ra ) from the lowest to the highest was : NT < FDB < MDB < AOCDB .\n\nLabels: 4\n\nSample: We conducted a randomized , double-blind trial of 536 patients at 38 medical centers evaluating slow-release ( SR ) and moderate-release ( MR ) formulations of a polymer-based paclitaxel-eluting stent ( TAXUS ) for revascularization of single , primary lesions in native coronary arteries .\n\nLabels: 4\n\nSample: After a median follow-up of 58 months , 5-year overall survival rates were 74 % in group 1 and 69 % in group 2 ; disease-free survival rates were 68 % and 62 % , respectively .\n\nLabels: 4\n\nSample: Manipulative therapy consisted of manipulation and mobilisation of the spine .\n\nLabels: 2\n\nSample: An infection was diagnosed in 5 and 4 patients in the OIENS + glyc and OIENS groups , respectively , and in 12 control patients .\n\nLabels: 4\n\nSample: Tai Chi Chuan ( TCC ) is a moderate form of exercise that may improve functional capacity and QOL in these individuals .\n\nLabels: 3\n\nSample: This study provides a baseline assessment of smoke-free polices in MUH settings .\n\nLabels: 1\n<Assistant>I've processed this information and will remember it.", "[Dialogue between User and Assistant on 2024-01-10 00:00]\n<User>The following classification examples include important label information:\n\nSample: Findings also contribute to conceptual clarification of essential aspects of the side effect experience and provide a basis for measure and intervention refinement .\n\nLabels: 1\n\nSample: At week 28 , the mean pooled index was 1.4 ( 95 % CI 1.2-1 .6 ) in the combined treatment group and 0.8 ( 0.6-1 .0 ) in the sulphasalazine group ( p < 0.0001 ) .\n\nLabels: 4\n\nSample: Pre-procedural and post-procedural data were compared between these groups .\n\nLabels: 2\n\nSample: Cuffed catheters were no more difficult to insert but took slightly longer to remove ( 6 minutes + / - 4.7 vs 5 minutes + / - 3 , P = .39 ) and often required local anesthesia for removal , whereas noncuffed catheters did not ( 41 % vs 0 % , P = .001 ) .\n\nLabels: 4\n\nSample: Second examinations showed significantly lower mean PIPP scores after examination ( 1min ( P = 0.003 ) and 5min ( P = 0.025 ) ) , regardless of the type of drop used .\n\nLabels: 4\n\nSample: Each patient received local infiltration with adrenaline-containing ( 5 microg/ml ) lidocaine ( 1 % , 4 ml ) under different conditions .\n\nLabels: 2\n\nSample: In the second sequence , ventilator hyperinflation preceded manual hyperinflation .\n\nLabels: 2\n\nSample: No author has a financial or proprietary interest in any material or method mentioned .\n\nLabels: 0\n\nSample: No significant difference was found between the daily dose of insulin ( regular , 5.83 + / -5.01 units ; lispro , 4.27 + / -3.40 units ) , total amount of insulin used during hospitalization ( regular , 11.87 + / -10.78 units ; lispro , 12.77 + / -14.39 units ) , glucose excursion ( regular , 110.13 + / -25.86 mg/dl ; lispro , 106.77 + / -52.65 mg/dl ) , or length of hospital stay ( regular , 2.33 + / -1.23 days ; lispro , 2.69 + / -1.59 days ) .\n\nLabels: 4\n\nSample: Treatment outcomes ( subjective improvement , self recorded frequency of wetting ) were equally satisfactory in both groups .\n\nLabels: 4\n\nSample: Allocation was to 1 of 3 treatment groups : conventional brackets , active self-ligating , or passive self-ligating brackets .\n\nLabels: 2\n\nSample: However , the placebo-KT group did not show significant changes in pain , AROM , or proprioception .\n\nLabels: 4\n\nSample: This may be related to intestinal manipulation and mesenteric traction which are reduced in the extraperitoneal approach .\n\nLabels: 1\n\nSample: Moreover , patients who felt more `` rested '' after sleeping the night following a treatment session had lower levels of symptoms and global severity at the next session , controlling for their symptoms and severity scores the previous session .\n\nLabels: 4\n\nSample: Combined psychotherapy and pharmacotherapy did not produce a significant reduction in HIV drug risk beyond that seen in an assessment-only control group .\n\nLabels: 1\n\nSample: Compared with the PMI , the PRCI was rated as more helpful and suitable for the situation , helping women to feel more positive and better helping to sustain efforts to cope .\n\nLabels: 4\n\nSample: The effect of sedation was assessed every hour till BIS reaching 50-70 or SAS reaching grade 3-4 .\n\nLabels: 2\n\nSample: Pelvic floor muscle training ( PFMT ) is a treatment for stress urinary incontinence ( SUI ) that can be done individually or in a group .\n\nLabels: 3\n\nSample: After 12 weeks , linagliptin 2.5 mg twice daily and 5mg once daily both significantly reduced HbA1c ( placebo-adjusted changes from baseline -0.74 % ( 95 % CI -0.97 , -0.52 ) and -0.80 % ( 95 % CI -1.02 , -0.58 ) , respectively , both p < 0.0001 ) .\n\nLabels: 4\n\nSample: In a randomised , open label study 12 healthy volunteers applied the lyophilised fluorescein to one eye and one drop of conventional fluorescein ophthalmic solution to the fellow eye .\n\nLabels: 2\n\nSample: A total of 303 men ( mean age 60 years ) with preoperative normal erectile function who had undergone a BNSRRP 12 to 48 months before study were randomized ( 2:1 ) to tadalafil ( 201 ) or placebo ( 102 ) .\n\nLabels: 2\n\nSample: Nutritional and topical antioxidants and immuno-modulant compounds play a key role in maintaining healthy skin .\n\nLabels: 0\n\nSample: Forty two women with polycystic ovarian disease and primary recurrent spontaneous abortions .\n\nLabels: 2\n\nSample: Lichenification ( t = 2.5 , p = 0.024 ) , xerosis ( t = 10.2 , p < 0.001 ) and pruritus ( t = 13.7 , p < 0.0001 ) also diminished significantly .\n\nLabels: 4\n\nSample: At six months , we observed a SBP reduction of 10 mmHg - primary outcome - in 48 % of the intervention group and 43 % of the control group .\n\nLabels: 4\n\nSample: The authors tested the impact of these computer services on the management of 179 pregnant women who had used cocaine during pregnancy or 1 month before pregnancy ( as reported by the woman ) .\n\nLabels: 2\n\nSample: Subjects consumed 1 L/d of either a control enteral formula ( n = 25 ; control group ) or a formula supplemented with arginine , omega-3 fatty acids , and RNA ( n = 25 ; verum group ) for 1 week before surgery .\n\nLabels: 2\n\nSample: A randomised double-blind cross-over study enrolled 17 patients suffering from coronary heart disease ( CHD ) with stable angina of effort ( SAE ) .\n\nLabels: 2\n\nSample: Eight weeks of treatment significantly decreased systolic blood pressure and diastolic blood pressure in both the aliskiren group and ramipril group .\n\nLabels: 4\n\nSample: Patients with multifocal aspheric IOL had significantly higher accommodative amplitude than those with monofocal spherical IOL , improved about 2.3 2.8 D ( Z = -10.655 , P = 0.000 ; Z = -2.709 , P = 0.007 ) .\n\nLabels: 4\n\nSample: Heart rate and arterial blood pressures decreased post SDA and were consistently lower in X versus B ( p < 0.05 ) .\n\nLabels: 4\n\nSample: Structured treatment interruptions of highly-active antiretroviral therapy ( HAART ) might be particularly relevant for sub-Saharan Africa , where cost-saving strategies could help to increase the number of patients on HAART .\n\nLabels: 0\n\nSample: Skin-to-skin contact infants had lower infant teaching scores at six months , a difference that disappeared thereafter .\n\nLabels: 4\n\nSample: Baseline health history , physical examination , and laboratory data for 205 HPV16 DNA-positive women with no prior cytologic evidence of squamous intraepithelial lesions who were enrolled subsequently in a randomized clinical trial .\n\nLabels: 2\n\nSample: Sample conformed by 50 patients over 65 years ( 48 % casein , 52 % soybean ) without statistically significant differences in age nor cause of indication of the EN .\n\nLabels: 4\n\nSample: At week 6 , tanezumab marginally improved the average daily pain ( least-squares mean difference from placebo -0.47 , 90 % confidence interval -1.150 -0.209 ) and urgency episode frequency ( least-squares mean difference from placebo -1.37 , 90 % confidence interval -3.146 -0.401 ) .\n\nLabels: 4\n\nSample: The proportion in whom lesions were both detected and the distribution correctly assessed as WACA or ostial was higher with 3D fusion imaging compared to LGE imaging ( 54 % vs 28 % ; P = 0.014 ) .\n\nLabels: 4\n<Assistant>Thanks for letting me know. I'll keep track of this."]
[{"question": "Sentence: Death occurred , respectively , in 4 % , 3 % , and 4 % ; thromboembolic vascular events occurred in 3 % , 5 % , and 3 % ; and serious adverse events occurred in 22 % , 26 % , and 26 % of subjects .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: No serious adverse reaction was reported in each group .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The importance of the postprandial glycemic and insulinemic responses for appetite and energy intake ( EI ) is controversial .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Two hundred patients who were scheduled to undergo valve repair and/or replacement surgery with or without coronary surgery were enrolled in the study .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Experimental , blinded , randomized , crossover study .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: In Kaplan-Meier analyses , T ( > 0.05 ) > or = 10.6 hours ( P = 0.023 ) , AUC of total paclitaxel > or = 4.7 microg/mL x hour ( P = 0.047 ) , and AUC of unbound paclitaxel > or = 0.375 microg/mL x hour ( P = 0.095 ) were identified as being potential factors for peripheral neuropathy development .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: In pericardial blood of patients undergoing cardiac surgery with CPB , microparticles contribute to activation of the complement system via bound SAP and IgM .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Among patients with diarrhea , clonidine increased stool consistency , with a borderline significant improvement in fecal continence .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: The effervescent formulations produced a transient rise in pH immediately following dosing , and for 300 mg this rise was significantly different at 10-20 min compared with the standard tablet ( median pH 4.75 vs. 2.3 , P < 0.05 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Amrubicin did not improve survival when compared with topotecan in the second-line treatment of patients with SCLC .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Measurements will be performed by research assistants not aware of group assignment .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Tertiary care university hospital .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Results show that : ( 1 ) high rHuEPO doses ( groups A and C1 ) were associated with decreased ROM production , low alpha-T levels , and slightly increased - SH levels compared with corresponding groups on low rHuEPO doses ( groups B and C2 ) ; ( 2 ) treatment with CL-Es ( group C ) increased plasma alpha-T and decreased - SH levels ; these data were associated with decreased indices of lipid peroxidation , particularly MDA-4HNE 1evels , only in patients administered low rHuEPO doses ; ( 3 ) alpha-T concentration influenced RBC survival , which was remarkably decreased in HD patients ; patients treated with CL-Es showed a better degree of anemia correction ; and ( 4 ) alpha-T level correlated negatively with - SH level and seemed to be independent of the extent of peroxidation and oxidizability of plasma lipids .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Multicenter , randomized clinical trial of 411 participants .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Dietary , anthropometric , and morbidity data are also being collected .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Additives did not affect color change in the alizarin red group .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: There was no significant difference between vagotomized patients and community controls in the reporting of abdominal ( P = 0.2 ) or dyspeptic ( P = 0.9 ) complaints .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Baseline characteristics and development of hypertension on treatment were studied as prognostic factors .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Mean pain score was lower in the MI group at postoperative days 2 and 4 .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The Finnish Invasive Pneumococcal disease ( FinIP ) vaccine trial was designed to assess the effectiveness of a pneumococcal vaccine containing ten serotype-specific polysaccharides conjugated to Haemophilus influenzae protein D , tetanus toxoid , and diphtheria toxoid as the carrier proteins ( PHiD-CV10 ) against invasive pneumococcal disease .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Midazolam offers the benefits of amnesia , reduced alertness , and reduced blood pressure with no clinically significant adverse effects .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Study criteria included corrected distance visual acuity ( CDVA ) , wavefront aberrometry , and contrast visual acuity .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: By using regression analysis in a random-effects model , subjects receiving itraconazole had a decrease in sputum eosinophils of 35 % per week , with no decrease seen in the placebo arm ( P < .01 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Both intranasal and oral E2/NET ( A ) therapy improved the lipid profile of healthy postmenopausal women , with some effects being more pronounced after oral administration .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: None of the women in either group developed endometritis .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Cardiopulmonary bypass ( CPB ) evokes a systemic inflammatory response .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Punctal occlusion using cautery was performed in each eye after a specified time following the application of anaesthesia .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: A total of 304 patients were randomly assigned to receive posaconazole , and 298 patients were randomly assigned to receive fluconazole ( 240 ) or itraconazole ( 58 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: All the patients were hospitalized at the Gulhane Military Medical Academy , Department of Infectious Diseases and Clinical Microbiology .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Both groups showed significant implicit sequence learning throughout the experiment .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: In women treated with misoprostol , however , this choice depended on the initial success of misoprostol : in cases where misoprostol had caused complete evacuation , 76 % of the women would opt for the same treatment , whereas only 38 % of women who needed curettage after unsuccessful misoprostol would do so ( P < 0.01 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The polymorphic angiotensinogen ( AGT ) gene is one of the most promising candidates for essential hypertension .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: The addition of bismuth subcitrate can be considered a valuable adjuvant to triple therapy in those areas where H. pylori shows a high resistance to fluoroquinolones .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: clinicaltrials.gov Identifier : NCT00505596 .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: No evidence was found for additional beneficial effects of spouse participation in the cognitive-behavioral oriented self-management group treatment .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: No statistically significant difference was observed in terms of severity of symptoms at presentation .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: During surgery , the hyperglycemic index and the glycemic penalty index were lower in the ND-ind group ( p < 0.05 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Secondary outcomes were the mortality rate , the respiratory rate , dyspnoea score , arterial blood gases .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Photodynamic therapy of acne vulgaris using 5-ALA 0.5 % liposomal spray and IPL in combination with topical peeling agents is safe and efficacious , even in patients with acne recalcitrant to standard therapy .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: The aim of this randomized controlled trial was to investigate differences in occurrence of adverse events between three different combinations of manual treatment techniques used by manual therapists ( i.e. chiropractors , naprapaths , osteopaths , physicians and physiotherapists ) for patients seeking care for back and/or neck pain .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Each GP received a calibrated SECURUS before the start of the study and was asked to include 2 treated hypertensive patients and one newly diagnosed patient .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Limited solutions are available to relieve the discomfort associated with breast engorgement .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: However , post pre-treatment did not affect the bonding efficacy of the adhesives except for Clearfil New Bond .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: A study was designed to assess the acute hemodynamic and neurohumoral response to losartan in a controlled , blinded fashion .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: The total sedatives dosages ( mg : 5466.7 620.4 ) and average sedatives dosages [ mgh ( -1 ) kg ( -1 ) : 2.19 0.61 ] in CS group were significantly higher than those in CR group ( 4344.5 816.0 , 1.00 0.51 ) and DI group ( 4154.3 649.4 , 1.23 0.62 , all P < 0.01 ) , and there was no difference between CR group and DI group .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: We sought to determine whether mental imagery improves surgical performance of residents novice to cystoscopy .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: Non-parametric simulations were performed to quantify the uncertainty around the mean estimates and cost-effectiveness acceptability curves were made .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: Plasma concentrations were quantitated from repeated after-dosing blood samples by HPLC with ultraviolet detection for midazolam and HPLC with tandem mass spectrometry detection for cisapride and norcisapride .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Group B was used as control .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: After 14 + / - 1 months , single-photon absorptiometry of the wrist decreased by 1.8 % + / - 3.2 % in the untreated patients and 0.5 % + / - 4.1 % in the levothyroxine-treated patients ( p = NS ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The primary outcome was mental health problem severity as measured by the health of the nation outcome scales .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Effects on peripheral white blood cell ( WBC ) count , ex vivo whole blood lipopolysaccharide ( LPS ) - stimulated TNF - release and response to cutaneous allergen challenge were assessed concurrently with biomarkers for glucose tolerance and bone turnover .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Outcome parameters included objective ( duration , oxygen saturation ) and subjective measures ( standardised visual analogue scales ) of the endoscopy staff ( handling , insertion , retroflexion , tolerability , overall assessment ) and patients ( pain , unpleasantness , sore throat , choking , gagging , meteorism , anxiety , acceptability ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: A single , 8.5-mL dose of lidocaine formulation ( SHACT ) was administered ( to the portio , cervix , and uterus ) with a specially designed applicator .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Serum phosphorous decreased in all three treatment groups ( -0.038 , -0.268 and -0.257 mmol/l in the 3 , 6 and 9 g/day groups , respectively ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: From January 1992 to February 1997 , 957 patients with intermediate - or high-risk stage Ta T1 urothelial bladder cancer were randomized after transurethral resection to one of three treatment groups in the European Organization for Research and Treatment of Cancer Genito-Urinary Group phase 3 trial 30911 .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Educational programs that promote safe driving strategies among seniors are a popular approach for addressing this problem , but their safety benefit has yet to be demonstrated .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: The Lifestyle Interventions and Independence for Elders-Pilot study ( LIFE-P ) was a randomized controlled trial that compared a physical activity intervention to a non-exercise educational intervention among 424 older adults at risk for disability .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Subjects were studied twice for 2 consecutive nights , with each 2-night session approximately 1 week apart .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Cefonicid 1 g was given by intravenous infusion to alternate patients 30 minutes before the operation .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Poor neuromuscular control during sports activities is associated with non-contact lower extremity injuries .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: All subjects received different concentrations of pale sulfonated shale oil ( 2 % and 4 % ) , the active ingredient-free vehicle and a reference product containing 0.5 % hydrocortisone .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Two hundred singleton gestations with an indication for cervical ripening and induction of labor were randomized to receive either 50 microg of misoprostol intravaginally every 3 h or a 10-mg dinoprostone vaginal insert every 12 h for a maximum of 24 h. Statistical analysis included Student 's t test , the Mann-Whitney U test , chi2 analysis and Fisher 's exact test .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Among predominantly Hispanic diabetes patients in community safety net primary care clinics whose depression had improved over 1 year , more than one-third experienced symptom deterioration over the following year .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: The study was an open , randomized , 2-period , 2-sequence , 2-treatment crossover , involving 24 healthy male and female volunteers .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: The aim of this study was to investigate a possible relation between osteoporosis and bile acid turnover , measured as whole-body Se-75-HCAT retention ( WBR ) , in postmenopausal women .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: Age was an important predictor of completion of a first visit ( odds ratio 1.09 , 95 % confidence interval 1.02-1 .16 , P = 0.017 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: In alteplase treated AMI adjunctive dalteparin for 4-7 days seems to reduce the risk of early coronary artery occlusion and reinfarction .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: DHA status and fish oil supplementation were not associated with bone mass or markers of bone formation in adolescent boys , but IGF-1 increased with increasing DHA status .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: An agar well antimicrobial assay was performed with 3 E coli isolates that included a reference strain and 2 multidrug-resistant clinical isolates .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Analysis of week-to-week correspondence of the presence or absence of help-seeking episodes showed good agreement between TLFB and the agency records for most participants , although there was substantial variation .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: This study was conducted in 2 tertiary referral hospitals in United Kingdom over 4years .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: In infants with growth restriction at discharge there was a significant reduction of weight gain , fat mass gain , and bone mineral content deposition independently of the formula provided .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Echocardiography and angiograms were used to asses the pulmonary artery size .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: As long as the recommended doses are used , concomitant injections of ABO are safe and efficient , with no increase in adverse events .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: A randomized , open-label , multicenter trial .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Patients with symptomatic internal carotid artery stenosis50 % , enrolled in the International Carotid Stenting Study ( ICSS ) at a single centre , underwent detailed neuropsychological examinations before and 6 months after revascularisation .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: One of four questionnaire versions was distributed to participants .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: The Resynchronization-Defibrillation for Ambulatory Heart Failure Trial showed that implantable cardioverter defibrillator-CRT was associated with a significant reduction in the primary end point of all-cause mortality or heart failure hospitalization .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Major bleeding was seen in ten patients in the immediate group and seven in the standard care/rescue group ( 3.4 % vs 2.3 % , p = 0.47 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The purpose of this study is to evaluate the effects of moxibustion on blood pressure in individuals with pre - or stage I hypertension .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: From February 2003 to October 2008 , 80 patients with burn wounds of degree II were treated and randomly divided into two groups ( n = 40 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Effects of MOR on ISO MAC varied .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The WORC score at each postoperative time point was significantly better than the baseline value .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: When converted into the same units , mean difference between 24h urine protein and both PCR ( 0.03 g/day ) , and ACR ( 0.10 g/day ) , was small .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The greatest improvement in photodamage measures following 1 MAL-PDT were pigmentation , AK and erythema .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: Vitiligo is an acquired pigmentary disorder characterized by areas of depigmented skin resulting from loss of epidermal melanocytes .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: No patient experienced pulmonary toxicity severe enough to require hospitalization .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: The results provide evidence that the most common hip examination tests would likely be sufficiently reliable to allow agreement between examiners when discriminating between painful FAI and normal hips in a clinical setting .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "1"}, {"question": "Sentence: Improvements from baseline on the Sheehan disability scale ( -0.9 , 95 % confidence interval -1.5 to -0.2 ; P = 0.006 ) and global quality of life rating ( 0.7 , 0.2 to 1.2 ; P = 0.005 ) were significantly greater at six and 12 months in patients in the intervention group .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: To determine general practitioners ' concordance with clinical guidelines on the diagnosis and management of patients with dementia .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: CRS7 ( trend test ) was associated with risk for fibrosis progression ( P = 0.04 ) with adjusted hazard ratio of 1.27 ( 95 % confidence interval : 1.01-1 .58 ) and with cirrhosis ( P = 0.05 ) with adjusted odds ratio of 1.19 ( 1.00-1 .41 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: US National Cancer Institute at the National Institutes of Health .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: In the fi rst group , patients received unilateral valves aiming for total occlusion of one lobe .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: A short-term administration of allopurinol increases plasma concentrations of 1,25 ( OH ) 2D3 in mild to moderate renal failure , with or without hyperuricemia .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "0"}, {"question": "Sentence: Following a standardized study protocol we compared postoperative results on the operating day and one week , six weeks , six months and one year afterwards uni - and multivariate analysis and we also calculated the costs .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: In prostate needle biopsies the tumour grade is a strong factor for deciding therapy .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "3"}, {"question": "Sentence: Data were analyzed using the test for nonparametric data and Student t test for parametric data .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "2"}, {"question": "Sentence: Pain measured on the 10-point VAS scale was 2.44 in group I and 1.85 in group II ( P < 0.05 ) .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}, {"question": "Sentence: After an average of 87 months of follow-up , extracapsular cataract extraction and posterior chamber lens implantation reduced intraocular pressure by 4.4 + / - 3.3 mm Hg , reduced the number of medications by 1.28 + / - 0.86 , increased diopter vector of astigmatism by 1.49 , and was associated with visual field loss in six of 35 eyes .\n\nWhat are the labels for the above medical abstract sentence?", "answer": "4"}]