You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["Outcome", "Participant", "Intervention"].

Please return the output as a JSON object of the format: {"Participant" : ["patients with COPD", ...], "Intervention" : ["Atenolol", ...], "Outcome" : ["blood pressure", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Evaluation of a novel technique for wound closure using a barbed suture . BACKGROUND Suture knots present several disadvantages in wound closure , because they are tedious to tie and place ischemic demands on tissue . Bulky knots may be a nidus for infection , and they may extrude through skin weeks after surgery . Needle manipulations during knot-tying predispose the surgeon to glove perforation . A barbed suture was developed that is self-anchoring , requiring no knots or slack management for wound closure . The elimination of knot tying may have advantages over conventional wound closure methods . METHODS This prospective , randomized , controlled trial was designed to show that the use of barbed suture in dermal closure of the Pfannenstiel incision during nonemergent cesarean delivery surgery produces scar cosmesis at 5 weeks that is no worse than that observed with conventional closure using 3-0 polydioxanone suture . Cosmesis was assessed by review of postoperative photographs by a blinded , independent plastic surgeon using the modified Hollander cosmesis score . Secondary endpoints included infection , dehiscence , pain , closure time , and other adverse events . RESULTS The study enrolled 195 patients , of whom 188 were eligible for analysis . Cosmesis scores did not significantly differ between the barbed suture group and the control group . Rates of infection , dehiscence , and other adverse events did not significantly differ between the two groups . Closure time and pain scores were comparable between the groups . CONCLUSIONS The barbed suture represents an innovative option for wound closure . With a cosmesis and safety profile that is similar to that of conventional suture technique , it avoids the drawbacks inherent to suture knots .
{"Intervention": ["novel technique", "3-0 polydioxanone suture", "conventional closure", "barbed suture", "conventional suture", "wound closure using a"], "Outcome": ["pain", ", dehiscence", "Cosmesis scores", "Closure time and pain scores", "infection", "safety profile", "other adverse events", "Cosmesis", "dehiscence", "Rates of infection", "adverse events", "cosmesis", "closure time ,"], "Participant": ["cesarean", "195", "188", "dermal closure of the Pfannenstiel incision"]}