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Paper text:
mr . a.l . is a 27-year old male , who was originally diagnosed at the age of 6 with tourette s syndrome manifested by vocal tics , presented to his family physician with a 4-month history of hoarseness .
is treated for his tourette s syndrome using haloperidol 1 mg twice daily , clonazepam as needed and sertraline . on physical examination , he was found to have a hoarse voice and vocal tics .
direct flexible nasopharyngoscopy revealed a polypoid lesion originating from the free edge of the anterior left true vocal fold ( figure 1 ) .
this lesion was amenable to transoral endoscopic microsurgical resection using a carbon dioxide ( co2 ) laser , and after a discussion with the patient , he agreed to proceed with resection .
was also asked to completed the university of michigan voice - related quality of life ( v - rqol ) questionnaire which he scored 24 overall and considered his voice quality as poor .
no dysplasia or malignancy was identified and the lesion was diagnosed as a vocal cord polyp .
two weeks after endoscopic co2 resection of the left vocal fold lesion , repeat laryngoscopic examination revealed complete resolution of the lesion with no evidence of scarring or web .
repeated the v - rqol questionnaire post - operatively and scored 11 overall and rated his voice quality as very good .
the relationship between vocal trauma , smoking , and gastroesophageal reflux disease and vocal cord polyps is well documented.1 other rare cases of recurrent vocal cord polyps have been documented in relation to autoimmune diseases such as systemic lupus erythematosus and hashimoto s thyroiditis.2 while there is substantial evidence for vocal cord trauma , a review of literature failed to demonstrate previous documentation of a relationship between vocal tics or tourette syndrome and vocal fold lesions.410 the etiology , pathophysiology and clinical manifestations of vocal polyps and nodules are well understood .
traditionally , polyps are associated with intermittent intense vocal abuse and smoking while vocal nodules are thought to arise from chronic minor vocal cord abuse . in the case of mr .
, he has no history of using his voice professionally or episodes of intense trauma .
the cause of this patient s laryngeal lesion then is likely secondary to the history of chronic minor vocal cord abuse suffered from vocal tics in his tourette syndrome . in this way
, we also demonstrate that the minor laryngeal trauma has led to the development of a polyp rather than bilateral nodules .
as it has been shown previously , it can be difficult for a pathologist to distinguish polyps and nodules.11,12 as previously stated , we had treated his hoarseness by excising the causative lesion . on the other hand , should this situation recur in this patient given the continuing vocal tics , definitive treatment for the vocal tics should be pursued . unfortunately , unlike other incidences of vocal trauma , voice coaching would not be beneficial .
more recently , vincent et al.13 has shown the advantages of using botulinum toxin in the treatment of laryngeal tics . despite the possible confounding history of cigarette smoke exposure
moreover , the possibility of vocal cord polyps should not be isolated to those patients who use their voice professionally . with the evidence from this case report , further study into the prevalence of vocal cord lesions in patients with tourette syndrome manifested by vocal tics may be warranted .
hoarseness and dysphonia are often a result of vocal cord polyps which in turn , are linked to vocal trauma . 
 we report the case of vocal polyps in the setting of a 27-year old male with a history only remarkable for tourette syndrome . 
 we review the literature regarding etiology and pathophysiology of vocal cord lesions and propose vocal tics in tourette syndrome as an under - recognized etiology . in this way 
 , we also review therapies that may aid in treating not only the vocal cord lesions but also particularly in the setting of vocal tics .