Given an abstract from a research paper, your task is to identify and label relationships between chemical compounds and genes mentioned in the abstract.

The relationship type must be one of ['DOWNREGULATOR', 'SUBSTRATE', 'INDIRECT-REGULATOR', 'PART-OF', 'MODULATOR-ACTIVATOR', 'REGULATOR', 'INHIBITOR', 'COFACTOR', 'UPREGULATOR', 'ACTIVATOR', 'ANTAGONIST', 'NOT', 'INDIRECT-DOWNREGULATOR', 'SUBSTRATE_PRODUCT-OF', 'INDIRECT-UPREGULATOR', 'AGONIST', 'PRODUCT-OF', 'MODULATOR', 'DIRECT-REGULATOR', 'UNDEFINED', 'AGONIST-INHIBITOR', 'AGONIST-ACTIVATOR', 'MODULATOR-INHIBITOR'].

Please format your output as a JSON array. Each entry in the array should express a single relation, formatted as ["<Entity_A>", "<RELATION_A_B>", "<Entity_B>"]. If no relations can be found, please output an empty JSON array [].

Abstract:

Alpha-2B adrenergic receptor mediated hemodynamic profile of etomidate. Etomidate has been used since 1972 as an inductor and in maintaining anesthesia. There are multiple mechanisms that account for the biologic effects of etomidate. One of the most prominent features of this drug is that it provides anesthesia without gross changes in hemodynamic parameters. This feature allows using etomidate in patients with considerable cardiopulmonary compromise avoiding the characteristic hypotension produced by other anesthetics. The mechanism that provides the basis for its cardiovascular stability is the capacity to bind and stimulate peripheral alpha-2B adrenergic receptors with a subsequent vasoconstriction. Alterations in the function or number of these receptors may account for abnormal responses during etomidate induction.
[["etomidate", "REGULATOR", "Alpha-2B adrenergic receptor"]]