You will be shown the abstract of a medical clinical trial report. Your task is to extract all the findings from this report into a JSON array. Each finding should contain the following five elements:

- Intervention: The medical intervention being tested. This should be a text span copied from the input passage.
- Comparator: The baseline against which the intervention is being evaluated. This should be a text span copied from the input passage. If no comparator is reported, set to `null`.
- Outcome: The medical outcome whose effect is being measured. This should be a text span copied from the input passage.
- Effect: The effect of the intervention on the outcome, relative to the comparator. The effect should be one of the following three values: ("significantly increased", "significantly decreased", "no significant difference").
- Evidence: The evidence for the effect. This should be a text span copied from the input passage.

Please format your output as a JSON array. Each entry in the output should be an array containing the 5 elements listed above, in the following order: [<intervention>, <comparator>, <outcome>, <effect>, <evidence>].

For example, an output with two findings might read:
```
[["aspirin", "placebo", "headache severity", "significantly decreased", "Mean headache severity was significantly decreased in the aspirin group compared to the placebo group (p < 0.05)."], ["aspirin", "placebo", "weight loss", "no significant difference", "We did not observe any difference in weight loss between the group given aspirin relative to the control group"]]
```

There are 3 finding(s) in the abstract below. Please extract them. Output only the JSON array with these 3 findings. Do not include any additional text.

Abstract:
ABSTRACT: 
Background: Heavy exercise cause muscle damage associated with production of inflammatory
agents. The purpose of present study was to determine the effect of acute and 14-day Coenzyme Q10
supplementation on inflammatory, blood lactate and muscle damage in male middle-distance runners.
 <p> 
Methods: Eighteen male middle-distance runners in a randomized and quasi experimental study
were allocated into two equal groups: supplement group (n=9, Coenzyme Q10: 5mg/kg/day) and
placebo group (n= 9, Dextrose: 5mg/kg/day). After acute (1day) and 14-day supplementation, all
subjects were participated in a training like running (competitive 3000 meters). Blood samples were
obtained in the four phases: one hour before and 18-24 hours after two running protocols. Lactate,
serum interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), C-reactive protein (CRP) and
creatine kinase (CK) were analyzed. Repeated ANOVA and Bonferuni as a post hoc tests were used
to determine the changes in four stages. Differences between groups were determined by t-test.
 <p> 
Results: The results showed that acute and short-term Coenzyme Q10 supplementation had not
significant effect on basal parameters. The acute coenzyme Q10 supplementation attenuated only the
exercise-induced increase in response of the plasma CRP. The short-term (14-day) coenzyme Q10
supplementation attenuated the exercise-induced increase in response of the lactate, serum interleukin-
6, tumor necrosis factor-alpha, and CRP in male middle-distance runners. However, the acute
and short-term coenzyme Q10 supplementation had not any significant effect on the exerciseinduced
increase response of total serum creatine kinase.
 <p> 
Conclusion: Based on the present results, it can be concluded that the 14-day coenzyme Q10 supplementation
(5mg.kg-1.day-1) is more effective than the acute supplementation to overcome the
exercise-induced adverse responses in some oxidative, inflammatory and biochemical parameters.
Therefore, short-term coenzyme Q10 supplementation is recommended to reduce exercise-induced
adverse consequences.


Findings:
[["14-day coenzyme Q10 supplementation (5mg.kg-1.day-1)", "acute supplementation of Q10", "overcome the exercise-induced adverse responses", "significantly increased", "Based on the present results, it can be concluded that the 14-day coenzyme Q10 supplementation\r\r\r\r\n(5mg.kg-1.day-1) is more effective than the acute supplementation to overcome the\r\r\r\r\nexercise-induced adverse responses in some oxidative, inflammatory and biochemical parameters.\r\r\r\r\nTherefore, short-term coenzyme Q10 supplementation is recommended to reduce exercise-induced\r\r\r\r\nadverse consequences."], ["acute coenzyme Q10 supplementation ", "placebo", "exercise-induced increase in response of the plasma CRP", "significantly decreased", "The acute coenzyme Q10 supplementation attenuated only the\r\r\r\r\nexercise-induced increase in response of the plasma CRP. The short-term (14-day) coenzyme Q10\r\r\r\r\nsupplementation attenuated the exercise-induced increase in response of the lactate, serum interleukin-\r\r\r\r\n6, tumor necrosis factor-alpha, and CRP in male middle-distance runners. "], ["coenzyme Q10 supplementation ", "placebo", "levels of serum CK", "no significant difference", "the acute\r\r\r\r\nand short-term coenzyme Q10 supplementation had not any significant effect on the exerciseinduced\r\r\r\r\nincrease response of total serum creatine kinase."]]