You are presented with a paragraph from a COVID-19 literature. Classify the topics of this piece of text by choosing from the following categories:

- Epidemic Forecasting: The content relates to predictions about the spread of COVID-19.
- Treatment: The paragraph discusses therapeutic methods or medication for COVID-19.
- Prevention: The content covers measures to prevent the spread of COVID-19.
- Mechanism: The paragraph explains the biological mechanisms of the virus.
- Case Report: The content is a report of a COVID-19 case.
- Transmission: The paragraph discusses how COVID-19 is transmitted.
- Diagnosis: The content is about diagnosing COVID-19 in individuals.

Your classification should be provided as an element within a JSON array. The array should be formatted with topics enclosed in double quotes and separated by commas, following the JSON format, for example: ["Topic1", "Topic2", ...]. Include all applicable topics within the array. Your output should be a valid JSON array, and no additional text should be included in your response.

Article:

INTRODUCCION: en la actual pandemia de COVID-19, existe evidencia creciente que ha identificado el neurotropismo del virus SARS-CoV-2 y sus complicaciones neurologicas, incluida la enfermedad cerebrovascular isquemica y escasamente hemorragia cerebral (HC). OBJETIVO: describir las caracteristicas clinicas, radiologicas, de laboratorio y pronosticas de los pacientes con HC asociada al SARS-CoV-2. METODOS: se incluyeron pacientes consecutivos con prueba de PCR confirmatoria para infeccion por SARS-CoV-2 y HC. RESULTADOS: en un periodo de 90 dias, en un centro de referencia COVID-19 en Mexico, de 1108 pacientes con infeccion por SARS-CoV-2, se encontraron 4 pacientes (0.36%) con HC. Tenian una edad de 71(+/-12.2) anos, 2 eran mujeres. Se encontro que dos tenian factores de riesgo cardiovascular previos. En dos casos se encontro el origen en el nucleo dentado mientras que los otros dos correspondieron al talamo. Tres de los cuatro pacientes murieron. Postulamos que el descontrol hipertensivo, coagulopatia, trombocitopenia y la respuesta inmune inducida por el virus SARS-CoV-2 podrian desencadenar HC en un paciente con riesgo previo. CONCLUSIONES: la HC se asocia a la infeccion por SARS-CoV-2 con mal pronostico cuando se presenta. Los equipos de neurocirugia deben estar preparados para el tratamiento oportuno de estos pacientes. INTRODUCTION: In the current COVID-19 pandemic, there is a growing body of evidence that has identified the neurotropism of the SARS-CoV-2 virus and its neurological complications, including cerebrovascular disease, focusing mainly in ischemic and scarcely about hemorrhagic stroke (HS). OBJECTIVE: The objective of the study was to describe clinical, radiological, laboratory tests, and prognostic characteristics of patients with SARS-CoV-2 associated HS. METHODS: Consecutive patients with a confirmatory PCR test for SARS-CoV-2 infection and a HS demonstrated by head CT were included in the study. RESULTS: Over a period of 90 days, in a COVID-19 reference center in Mexico, out of a total of 1108 patients with SARS-CoV-2 infection, it found 4 patients (0.36%) who meet criteria. They had an age of 71 (+/-12.2) years, 2 were women. It was found that two had prior cardiovascular risk factors. Two of the HS originated in the dentate nucleus while the other two corresponded to the thalamus. Three of the four patients died. We suggest that catastrophic uncontrolled blood pressure, coagulopathy, thrombocytopenia, and immune response induced by SARS-CoV-2 could in a specific patient trigger HS. CONCLUSIONS: HS is associated to SARS-CoV-2 infection with poor prognosis when it presented. Neurosurgery teams should prepare for the timely and appropriate treatment of this patients.
["Case Report"]