You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["RNA", "CellLine", "Protein", "DNA", "CellType"].

Please return the output as a JSON object of the format: {"DNA" : ["TAL1", ...], "RNA": ["mRNAs", ...], "CellLine": ["T cells", ...], "CellType": ["monocytes", ...], "Protein": ["IL-2", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Human CD4 lymphocytes specifically recognize a peptide representing the fusion region of the hybrid protein pml / RAR alpha present in acute promyelocytic leukemia cells. Fusion proteins present in leukemic cells frequently contain a new amino acid at the fusion point. We tested whether a peptide (BCR1 / 25) encompassing the fusion region of the hybrid molecule pml / RAR alpha, which is selectively expressed by acute promyelocytic leukemia (APL) cells, can be recognized by human T lymphocytes in vitro. CD4 + lymphocytes, at both polyclonal and clonal level, recognized peptide BCR1 / 25 in an HLA-DR-- restricted fashion on presentation by autologous antigen-presenting cell (APC) or by APC expressing the HLA-DR11 restricting molecule. Control peptides corresponding to the normal pml and RAR alpha proteins were not recognized. One clone (DEG5) also exerted a high and specific cytotoxicity against autologous cells pulsed with BCR1 / 25. The autologous DE LCL containing a transduced pml / RAR alpha fusion gene and expressing a bcr1 type of the pml / RAR alpha hybrid protein induced the proliferation of DE anti-BCR1 / 25 T cell clones. It is concluded that the bcr1 type-pml / RAR alpha fusion protein of APL contains an antigenic site, absent from the normal parent molecules and recognized by human CD4 + lymphocytes.
{"CellLine": ["DE anti - BCR1 / 25 T cell clones", "autologous DE LCL", "human CD4 + lymphocytes", "DEG5", "APL", "autologous cells"], "CellType": ["Human CD4 lymphocytes", "autologous antigen - presenting cell", "APC", "human T lymphocytes", "acute promyelocytic leukemia (APL) cells", "human CD4 + lymphocytes", "CD4 + lymphocytes", "leukemic cells", "acute promyelocytic leukemia cells", "APL", "T lymphocytes"], "DNA": ["pml / RAR alpha fusion gene"], "Protein": ["bcr1 type", "HLA - DR", "Fusion proteins", "RAR alpha proteins", "fusion point", "HLA - DR11 restricting molecule", "hybrid protein", "pml", "bcr1 type - pml / RAR alpha fusion protein", "fusion region", "pml / RAR alpha"], "RNA": []}