You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["Outcome", "Participant", "Intervention"].

Please return the output as a JSON object of the format: {"Participant" : ["patients with COPD", ...], "Intervention" : ["Atenolol", ...], "Outcome" : ["blood pressure", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Safety and pharmacokinetics of hyperimmune anti-human immunodeficiency virus ( HIV ) immunoglobulin administered to HIV-infected pregnant women and their newborns . Pediatric AIDS Clinical Trials Group Protocol 185 Pharmacokinetic Study Group . The pharmacokinetics and safety of hyperimmune anti-human immunodeficiency virus ( HIV ) intravenous immunoglobulin ( HIVIG ) were evaluated in the first 28 maternal-infant pairs enrolled in a randomized , intravenous immunoglobulin ( IVIG ) -controlled trial of HIVIG maternal-infant HIV transmission prophylaxis . Using 200 mg/kg , mean half-life and volume of distribution ( Vd ) in women were 15 days and 72 mL/kg , respectively , after one and 32 days and 154 mL/kg after three monthly infusions , with stable 4 mL/kg/day clearance . Transplacental passage occurred . Newborn single-dose half-life , Vd , and clearance were 30 days , 143 mL/kg , and 4 mL/kg/day , respectively . HIVIG rapidly cleared maternal serum immune complex-dissociated p24 antigen , and plasma HIV-1 RNA levels were stable . Mild to moderate adverse clinical effects occurred in 2 of 103 maternal and 2 of 25 infant infusions . No adverse hematologic , blood chemistry , or immunologic effects were seen . HIVIG is well-tolerated in HIV-infected pregnant women and their newborns , clears antigenemia , crosses the placenta , and exhibits pharmacokinetics similar to those of other immunoglobulin preparations .
{"Intervention": ["hyperimmune anti-human immunodeficiency virus ( HIV ) intravenous immunoglobulin ( HIVIG )", "hyperimmune anti-human immunodeficiency virus ( HIV ) immunoglobulin", "HIVIG"], "Outcome": ["HIVIG rapidly cleared maternal serum immune complex-dissociated p24 antigen , and plasma HIV-1 RNA levels", "Safety", "adverse hematologic , blood chemistry , or immunologic effects", "well-tolerated", "adverse clinical effects", "pharmacokinetics", "safety"], "Participant": ["28", "women", "intravenous immunoglobulin", "HIV", "their newborns", "pregnant women", "maternal-infant pairs", "HIV-infected"]}