You will be shown inclusion or exclusion criteria for a clinical trial. Given these criteria, your task is to extract all unique entities of the following types: ["Observation", "Condition", "Procedure", "Drug", "Temporal", "Multiplier", "Qualifier", "Negation", "ReferencePoint", "Scope", "Value", "Mood", "Device", "Visit", "Measurement", "Person"].

Please return the output as a JSON object of the format: {"Condition" : ["breast cancer", ...], "Device" : ["ports", ...], "Drug" : ["Atenolol", ...], "Measurement" : ["blood pressure", ...], "Mood" : ["suspected", ...], "Multiplier" : ["more than two", ...], "Negation" : ["no", ...], "Observation" : ["history", ...], "Person" : ["male", ...], "Procedure" : ["surgery", ...], "Qualifier" : ["severe", ...], "ReferencePoint" : ["enrollment", ...], "Scope" : ["infection", ...], "Temporal" : ["one day", ...], "Value" : ["50%", ...], "Visit" : ["ICU", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Informed consent as documented by signature (see informed consent form)
Primary ITP according to the definition of Rodeghiero et al. (52) and a platelet count of <30x109/l
Age range: 18-45 years
Previously treated patients, with failure or intolerance to first-line therapy, or relapse after first-line therapy, i.e. corticosteroids, intravenous immunoglobulin (IVIG), or anti-D immunoglobulins
{"Condition": ["relapse", "Primary ITP"], "Device": [], "Drug": ["intravenous immunoglobulin", "corticosteroids", "anti-D immunoglobulins", "IVIG"], "Measurement": ["definition of Rodeghiero", "platelet count"], "Mood": [], "Multiplier": [], "Negation": [], "Observation": ["Previously treated"], "Person": ["Age"], "Procedure": ["first-line therapy"], "Qualifier": ["intolerance", "failure"], "ReferencePoint": ["first-line therapy"], "Scope": ["definition of Rodeghiero et al. (52) and a platelet count of \u003c30x109/l"], "Temporal": ["after first-line therapy"], "Value": ["\u003c30x109/l", "18-45 years"], "Visit": []}