You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["RNA", "CellLine", "Protein", "DNA", "CellType"].

Please return the output as a JSON object of the format: {"DNA" : ["TAL1", ...], "RNA": ["mRNAs", ...], "CellLine": ["T cells", ...], "CellType": ["monocytes", ...], "Protein": ["IL-2", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Expression of c-fos, c-jun and jun B in peripheral blood lymphocytes from young and elderly adults. The expression of c-fos, c-jun and jun B proto-oncogenes was studied in phytohemagglutinin (PHA) activated peripheral blood lymphocytes (PBL) from young and aged humans. Specific mRNAs for c-fos and c-jun were detectable within 30 min after cell activation and reached maximal levels within 2 h. Both c-fos and jun B mRNAs decreased to pre-activation levels within 6 h, while c-jun mRNA remained elevated. In PHA-activated PBL, no age-related differences were observed in c-fos or jun B mRNA expression. However, c-jun mRNA levels decreased significantly (1. 73 + /-0. 08 vs. 1. 16 + /-0. 09 arbitrary units, P < 0. 01, young vs. old) in PBL from elderly individuals activated with PHA. Because previous work has demonstrated that T cells from elderly individuals may display normal proliferative responses when activated via the anti-CD2 pathway, c-jun and jun B mRNA expression was also studied in anti-CD2-activated purified T cells. No age-related differences were found in the expression of either of these two proto-oncogenes by anti-CD2 activated T cells. These results suggest that the decreased IL-2 production and proliferative response displayed by PHA-activated PBL from elderly adults may be related to age-related changes in c-jun mRNA expression and in the ratio of c-fos to c-jun mRNA.
{"CellLine": ["PHA - activated PBL from elderly adults", "PHA - activated PBL", "elderly adults", "anti - CD2 - activated purified T cells", "phytohemagglutinin (PHA) activated peripheral blood lymphocytes"], "CellType": ["PBL", "T cells"], "DNA": ["c - fos", "jun B", "c - jun", "proto - oncogenes", "c - fos , c - jun and jun B proto - oncogenes"], "Protein": ["phytohemagglutinin", "PHA", "IL - 2", "anti - CD2"], "RNA": ["jun B mRNAs", "c - fos", "jun B", "c - jun mRNA", "c - fos and jun B mRNAs", "mRNAs"]}