You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["HealthCareActivity", "InjuryOrPoisoning", "BodySubstance", "IntellectualProduct", "AnatomicalStructure", "SpatialConcept", "Chemical", "Bacterium", "MedicalDevice", "Organization", "BiomedicalOccupationOrDiscipline", "Finding", "BiologicFunction", "Virus", "ResearchActivity", "ClinicalAttribute", "PopulationGroup", "Eukaryote", "BodySystem", "Food", "ProfessionalOrOccupationalGroup"].

Please return the output as a JSON object of the format: {"Virus": ["HIV", ...], "Bacterium": ["MRSA", ...], "AnatomicalStructure": ["Lung", ...], "BodySystem": ["CNS", ...], "BodySubstance": ["Serum", ...], "Finding": ["Headache", ...], "InjuryOrPoisoning": ["Fracture", ...], "BiologicFunction": ["Death", ...], "HealthCareActivity": ["Biopsy", ...], "ResearchActivity": ["Clinical trial", ...], "MedicalDevice": ["Lenses", ...], "SpatialConcept": ["Camps", ...], "BiomedicalOccupationOrDiscipline": ["Forensic medicine", ...], "Organization": ["WHO", ...], "ProfessionalOrOccupationalGroup": ["Provider", ...], "PopulationGroup": ["Swimmers", ...], "Chemical": ["Gold", ...], "Food": ["Rice", ...], "IntellectualProduct": ["RPAM", ...], "ClinicalAttribute": ["Biomarker", ...], "Eukaryote": ["Dogs", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Placental Pathologic Associations with Morbidly Adherent Placenta: Potential insights into Pathogenesis The pathology that underlies morbidly adherent placenta (MAP) is poorly understood. The objective of this study was to describe the placental pathology, especially implantation site pathology, associated with MAP. This was a single institution, retrospective case-control study design examining placentas of patients who delivered between January 2008 and September 2013. MAP cases were defined by the need for clinical intervention at delivery beyond spontaneous placental delivery or simple manual extraction of the placenta. Controls consisted of patients with placentas sent for examination due to a history of maternal malignancy with no clinical suspicion of accreta. Placental pathologic findings of maternal vascular underperfusion (MVU), acute inflammation, chronic inflammation, fetal vascular obstruction and hemorrhage were recorded and compared using bivariable and multivariable analyses. Three categories of pathologic changes were seen more commonly in MAP placentas (N=101) than control placentas (N=110): chronic basal inflammation, villous changes of MVU and retromembranous and retromembranous / intervillous hemorrhage. In multivariable analyses adjusted for confounders, chronic basal villitis (aOR 5.6, 1.73-18.18), plasma cell deciduitis (aOR 2.63, 1.08-6.39), increased syncytial knots (aOR 3.92, 1.57-9.75), villous agglutination (aOR 24.85, 2.78-221.75), increased perivillous fibrin (aOR 5.08, 1.49-17.34), and the presence of subchorionic / intervillous thrombi (aOR 4.01, 1.63-9.86) remained associated with MAP. MAP is highly associated with evidence of intraparenchymal placental hemorrhage villous changes of MVU, and a lymphoplasmacytic infiltrate at the implantation site. The contribution of this basal chronic inflammatory infiltrate to MAP requires further investigation.
{"AnatomicalStructure": ["placental", "placentas", "fetal", "placenta", "Placental"], "Bacterium": [], "BiologicFunction": ["chronic basal inflammation", "retromembranous", "vascular obstruction", "subchorionic", "morbidly adherent placenta", "chronic inflammation", "malignancy", "Morbidly Adherent Placenta", "MAP", "maternal vascular underperfusion", "MVU", "accreta", "intervillous hemorrhage", "intraparenchymal placental hemorrhage", "hemorrhage", "chronic basal villitis", "Pathogenesis"], "BiomedicalOccupationOrDiscipline": [], "BodySubstance": [], "BodySystem": [], "Chemical": [], "ClinicalAttribute": [], "Eukaryote": [], "Finding": ["plasma cell deciduitis", "intervillous thrombi", "no", "lymphoplasmacytic infiltrate", "acute inflammation", "basal chronic inflammatory infiltrate", "increased syncytial knots", "increased perivillous fibrin", "history", "delivered"], "Food": [], "HealthCareActivity": ["examination", "placental delivery", "delivery", "intervention", "manual extraction"], "InjuryOrPoisoning": [], "IntellectualProduct": ["categories"], "MedicalDevice": [], "Organization": ["institution"], "PopulationGroup": [], "ProfessionalOrOccupationalGroup": [], "ResearchActivity": ["retrospective case-control study"], "SpatialConcept": ["implantation site"], "Virus": []}