You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["RNA", "CellLine", "Protein", "DNA", "CellType"].

Please return the output as a JSON object of the format: {"DNA" : ["TAL1", ...], "RNA": ["mRNAs", ...], "CellLine": ["T cells", ...], "CellType": ["monocytes", ...], "Protein": ["IL-2", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

The cellular oncogene c-myb can interact synergistically with the Epstein-Barr virus BZLF1 transactivator in lymphoid cells. Regulation of replicative functions in the Epstein-Barr virus (EBV) genome is mediated through activation of a virally encoded transcription factor, Z (BZLF1). We have shown that the Z gene product, which binds to AP-1 sites as a homodimer and has sequence similarity to c-Fos, can efficiently activate the EBV early promoter, BMRF1, in certain cell types (i. e., HeLa cells) but not others (i. e., Jurkat cells). Here we demonstrate that the c-myb proto-oncogene product, which is itself a DNA-binding protein and transcriptional transactivator, can interact synergistically with Z in activating the BMRF1 promoter in Jurkat cells (a T-cell line) or Raji cells (an EBV-positive B-cell), whereas the c-myb gene product by itself has little effect. The simian virus 40 early promoter is also synergistically activated by the Z / c-myb combination. Synergistic transactivation of the BMRF1 promoter by the Z / c-myb combination appears to involve direct binding by the Z protein but not the c-myb protein. A 30-bp sequence in the BMRF1 promoter which contains a Z binding site (a consensus AP-1 site) is sufficient to transfer high-level lymphoid-specific responsiveness to the Z / c-myb combination to a heterologous promoter. That the c-myb oncogene product can interact synergistically with an EBV-encoded member of the leucine zipper protein family suggests c-myb is likely to engage in similar interactions with cellularly encoded transcription factors.
{"CellLine": ["HeLa cells", "Raji cells", "T - cell line", "Jurkat cells", "EBV - positive B - cell"], "CellType": ["lymphoid cells"], "DNA": ["cellular oncogene", "heterologous promoter", "EBV early promoter", "BMRF1 promoter", "30 - bp sequence", "the BMRF1 promoter", "c - myb", "AP - 1 sites", "BMRF1", "consensus AP - 1 site", "Z binding site", "simian virus 40 early promoter", "Epstein - Barr virus (EBV) genome", "c - Fos"], "Protein": ["c - myb protein", "leucine zipper protein family", "virally encoded transcription factor", "BZLF1", "DNA - binding protein", "leucine zipper", "c - myb oncogene product", "Z gene product", "Z protein", "transcriptional transactivator", "Z / c - myb combination", "Z", "c - myb proto - oncogene product", "cellularly encoded transcription factors", "homodimer", "transcription factors", "c - myb gene product", "EBV - encoded member", "Epstein - Barr virus BZLF1 transactivator"], "RNA": []}