You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["Outcome", "Participant", "Intervention"].

Please return the output as a JSON object of the format: {"Participant" : ["patients with COPD", ...], "Intervention" : ["Atenolol", ...], "Outcome" : ["blood pressure", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Treatment of hypertensive and hypercholesterolaemic patients in general practice . The effect of captopril , atenolol and pravastatin combined with life style intervention . OBJECTIVE To elucidate the effect on blood pressure and blood lipids of an angiotensin converting enzyme inhibitor ( captopril ) , and a beta-receptor blocking agent ( atenolol ) , given alone or in combination with a cholesterol reducing drug , the beta-hydroxy-methylglutaryl-coenzyme A reductase inhibitor pravastatin , in patients who were also encouraged to improve their lifestyle . DESIGN A longitudinal study consisting of three phases . I : Lifestyle intervention alone . II : Continued lifestyle intervention combined with captopril or atenolol . III : Continued lifestyle intervention combined with the same drugs as in phase II and in addition pravastatin or placebo . SETTING Fifty-four general practice surgeries in Norway . PARTICIPANTS Hypertensive patients , 210 females and 160 males , treated or untreated with antihypertensive drugs with a sitting diastolic blood pressure between 95 and 115 mmHg and a serum total cholesterol between 6.5 mmol/l ( 7.0 for those age 60-67 years ) and 9.0 mmol/l . RESULTS The antihypertensive effect of captopril and atenolol was not influenced by concurrent administration of pravastatin . The effect of pravastatin was not limited by concurrent medication with captopril or atenolol . Improvement in lifestyle seemed to reduce the need for supplementary treatment with diuretics . CONCLUSION Pravastatin can be used in combination with captopril or atenolol in the treatment of hypertensive and hypercholesterolaemic patients .
{"Intervention": ["angiotensin converting enzyme inhibitor ( captopril )", "cholesterol reducing drug", "lifestyle intervention combined with the same drugs as in phase II", "placebo", "diuretics", "pravastatin", "captopril", "beta-hydroxy-methylglutaryl-coenzyme A reductase inhibitor pravastatin", "pravastatin combined with life style intervention", "Continued lifestyle intervention combined with captopril or atenolol", "Continued", "Lifestyle intervention alone", "Pravastatin", "atenolol", "were also encouraged to improve their lifestyle", "beta-receptor blocking agent ( atenolol )"], "Outcome": ["Improvement in lifestyle", "supplementary treatment with diuretics"], "Participant": []}