You will be presented with a collection of medical randomized controlled trial (RCT) reports addressing a shared clinical question -- for instance, the efficacy of a medical intervention on a disease or condition. Given the titles and abstracts of these reports, your task is to generate the conclusion of the systematic review article synthesizing the key findings. Your conclusion should be a few sentences long. In your response, include only the conclusion and no other text. The RCT reports are below.



Title 1:
Influence of fruit consumption and fluoride application on the prevalence of caries and erosion in vegetarians—a controlled clinical trial
Abstract 1:
Background / Objectives : Caries and erosion are common diseases of the dental hard tissues . The influence of vegetarianism on the development of caries and erosion has scarcely been investigated in the past . The aim of the present study was to evaluate the influence of fruit consumption and topical fluoride application on the prevalence of caries and erosion  in vegetarians . Subjects/ Methods : In 100 vegetarians and 100 nonvegetarians , a dental examination was performed . The indices for decayed , missing , filled teeth ( DMFT ) and surfaces ( DMFS ) were determined . DMFT and DMFS were subdivided into decayed teeth ( DT ) , filled teeth ( FT ) , decayed surfaces ( DS ) and filled surfaces ( FS ) . In addition , the hygiene index and the number of teeth with dental erosion ( DE ) , root caries ( RC ) and overhanging restoration margins ( ORM ) were recorded . A question naire assessed patients ’ eating habits , frequency of oral hygiene , dentist visits and  topical fluoride application . For statistical analysis , unpaired t-test , Mann – Whitney test and Pearson ’s chi-square test were applied . Results : Vegetarians had significantly more DT ( P<0.001 ) , DS ( P<0.001 ) , more teeth with DE ( P=0.026 ) , RC ( P=0.002 ) and ORM ( P<0.001 ) than nonvegetarians . Daily consumption of fruits was significantly more prevalent ( P<0.001 ) , and  topical fluoride application was less prevalent ( P<0.001 ) in vegetarians compared with nonvegetarians . In particular , fluoride-containing toothpaste ( P<0.001 ) and table salt ( P=0.039 ) were less frequently used in vegetarians . Conclusion : The presented data suggest that vegetarians have an increased risk for caries and erosion .  Topical fluoride application was shown to be effective in preventing caries , but not in preventing erosion


Title 2:
Effects of fluorotherapy on oral changes caused by a vegan diet.
Abstract 2:
AIM The aim of this paper was to investigate the effects of fluorotherapy on the oral health of subjects who had been following a vegan diet ( lacking in meat and animal derivatives ) for a long period of time ( at least 1 year and 6 months ) . METHODS A preliminary study ( t0 ) evaluated 50 subjects , all from northern Italy and aged 24 - 60 years ( 28 male and 22 female ) who had been following a vegan diet for a minimum of 18 months to a maximum of 20 years , and compared them with a control group of 50 individuals following a Mediterranean diet .  All vegan subjects showed oral changes such as white spots , lesions invisible to the naked eye and decreased salivary pH values ( ~5 - 6 ) . In a second study ( t1 ) , the 50 vegan subjects were r and omly divided into two subgroups of 25 . Subgroup SG1 underwent fluorotherapy with sodium fluoride ( Elmex fluoride gel ® 1.25 % ) administered once daily for 1 year . Subgroup SG2 served as controls and did not receive fluorotherapy . The following parameters were recorded before the start of fluorotherapy and again after 1 year : salivary pH ; Decayed , Missing , Filled teeth Index ; presence and location of white spots and lesions not visible to the naked eye ; Plaque Index , and Gingival Index . RESULTS In SG1 , larger lesions became smaller in diameter and small lesions disappeared , a statistically significant improvement compared with SG2 , despite the persistence of restricted eating habits and the oral hygiene conditions being similar to those at t0 . Salivary pH showed no significant change in either subgroup . CONCLUSION Daily application of a topical 1.25 % fluoride gel is effective in reducing the incidence of white spot lesions caused by a vegan diet
There was inconsistent evidence for a link between following a vegetarian diet and dental caries or the number of natural teeth .
Conclusions Within the limitations of the present study , the findings suggest that following a vegetarian diet may be associated with a greater risk of dental erosion