You will be shown inclusion or exclusion criteria for a clinical trial. Given these criteria, your task is to extract all unique entities of the following types: ["Observation", "Condition", "Procedure", "Drug", "Temporal", "Multiplier", "Qualifier", "Negation", "ReferencePoint", "Scope", "Value", "Mood", "Device", "Visit", "Measurement", "Person"].

Please return the output as a JSON object of the format: {"Condition" : ["breast cancer", ...], "Device" : ["ports", ...], "Drug" : ["Atenolol", ...], "Measurement" : ["blood pressure", ...], "Mood" : ["suspected", ...], "Multiplier" : ["more than two", ...], "Negation" : ["no", ...], "Observation" : ["history", ...], "Person" : ["male", ...], "Procedure" : ["surgery", ...], "Qualifier" : ["severe", ...], "ReferencePoint" : ["enrollment", ...], "Scope" : ["infection", ...], "Temporal" : ["one day", ...], "Value" : ["50%", ...], "Visit" : ["ICU", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

1. Age ≥ 18 years 
2. Patient with breast cancer, histologically proven, metastatic or locally advanced 
3. Patient treated by Eribulin between January and October 2014 (for the retrospective part) or between November 2014 and September 2015 (for the prospective part). 
4. Patient with at least an assessment of the response to Eribulin
{"Condition": ["breast cancer"], "Device": [], "Drug": ["Eribulin"], "Measurement": [], "Mood": [], "Multiplier": [], "Negation": [], "Observation": [], "Person": ["Age"], "Procedure": ["assessment of the response", "histologically"], "Qualifier": ["locally advanced", "metastatic"], "ReferencePoint": [], "Scope": ["histologically proven, metastatic or locally advanced", "between January and October 2014 (for the retrospective part) or between November 2014 and September 2015 (for the prospective part)"], "Temporal": ["between January and October 2014", "between November 2014 and September 2015"], "Value": ["\u2265 18 years", "proven"], "Visit": []}