You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["RNA", "CellLine", "Protein", "DNA", "CellType"].

Please return the output as a JSON object of the format: {"DNA" : ["TAL1", ...], "RNA": ["mRNAs", ...], "CellLine": ["T cells", ...], "CellType": ["monocytes", ...], "Protein": ["IL-2", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Nuclear factor of activated T cells contains Fos and Jun. The nuclear factor NF-AT (ref. 1) is induced in T cells stimulated through the T-cell receptor / CD3 complex, and is required for interleukin-2 (IL-2) gene induction. Although NF-AT has not been cloned or purified, there is evidence that it is a major target for immunosuppression by cyclosporin A (CsA) and FK506 (refs 2-7). NF-AT induction may require two activation-dependent events: the CsA-sensitive translocation of a pre-existing component and the CsA-resistant synthesis of a nuclear component. Here we report that the newly synthesized nuclear component of NF-AT is the transcription factor AP-1. We show that the inducible nuclear form of NF-AT contains Fos and Jun proteins. Furthermore, we identify a pre-existing NF-AT-binding factor that is present in hypotonic extracts of unstimulated T cells. On the basis of binding, reconstitution and cotransfection experiments, we propose that activation of NF-AT occurs in at least two stages: a CsA-sensitive stage involving modification and / or translocation of the pre-existing NF-AT complex, and a CsA-insensitive stage involving the addition of newly synthesized Fos or Fos / Jun proteins to the pre-existing complex.
{"CellLine": [], "CellType": ["unstimulated T cells", "activated T cells", "T cells"], "DNA": ["interleukin - 2 (IL - 2) gene"], "Protein": ["nuclear factor NF - AT", "Fos", "transcription factor", "nuclear component", "NF - AT complex", "pre - existing complex", "interleukin - 2", "Fos / Jun proteins", "T - cell receptor / CD3 complex", "Nuclear factor", "AP - 1", "pre - existing NF - AT - binding factor", "Jun", "IL - 2", "NF - AT"], "RNA": []}