You will be shown inclusion or exclusion criteria for a clinical trial. Given these criteria, your task is to extract all unique entities of the following types: ["Observation", "Condition", "Procedure", "Drug", "Temporal", "Multiplier", "Qualifier", "Negation", "ReferencePoint", "Scope", "Value", "Mood", "Device", "Visit", "Measurement", "Person"].

Please return the output as a JSON object of the format: {"Condition" : ["breast cancer", ...], "Device" : ["ports", ...], "Drug" : ["Atenolol", ...], "Measurement" : ["blood pressure", ...], "Mood" : ["suspected", ...], "Multiplier" : ["more than two", ...], "Negation" : ["no", ...], "Observation" : ["history", ...], "Person" : ["male", ...], "Procedure" : ["surgery", ...], "Qualifier" : ["severe", ...], "ReferencePoint" : ["enrollment", ...], "Scope" : ["infection", ...], "Temporal" : ["one day", ...], "Value" : ["50%", ...], "Visit" : ["ICU", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Male or female patients = 18 and = 85 years of age
Women of child bearing potential must test negative on standard pregnancy test (urine or serum)
Patients with body weight = 55 kg and = 140 kg and body mass index (BMI) = 18 kg/m2
Patients diagnosed severe sepsis / septic shock at admission on Intensive Care Unit who can be enrolled within 90 min after admission OR patients diagnosed severe sepsis / septic shock during Intensive Care Unit stay who can be enrolled within 90 min after diagnosis
Patients where antibiotic therapy has already been started (prior to randomization)
Patient who are fluid responsive. Fluid responsiveness is defined as increase of > 10% in mean arterial pressure (MAP) after passive leg raising (PLR)
Signed informed consent by patient, legal representative or authorized person or deferred consent
{"Condition": ["child bearing potential", "fluid responsive", "severe sepsis", "septic shock"], "Device": [], "Drug": ["antibiotic therapy"], "Measurement": ["urine", "body weight", "body mass index (BMI)", "serum", "mean arterial pressure (MAP)", "standard pregnancy test"], "Mood": [], "Multiplier": [], "Negation": [], "Observation": [], "Person": ["Women", "age", "Male", "female"], "Procedure": [], "Qualifier": ["after passive leg raising (PLR)"], "ReferencePoint": ["randomization", "admission on Intensive Care Unit"], "Scope": ["Women of child bearing potential", "urine or serum"], "Temporal": ["prior to randomization", "at admission on Intensive Care Unit"], "Value": ["= 55 kg and = 140 kg", "negative", "\u003e 10%", "= 18 kg/m2", "= 18 and = 85 years"], "Visit": []}