You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["Outcome", "Participant", "Intervention"].

Please return the output as a JSON object of the format: {"Participant" : ["patients with COPD", ...], "Intervention" : ["Atenolol", ...], "Outcome" : ["blood pressure", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

The role of the MA-sensitive leukocyte chemotaxis in rheumatoid arthritis . A randomized double-blind clinical trial of griseofulvin treatment . Polymorphonuclear leukocyte ( PMN ) chemotaxis is thought to play an essential role in the pathogenesis of rheumatoid arthritis . PMN chemotaxis is in part sensitive to microtubule antagonists ( MAs ) , e.g . colchicine . The antimycotic antibiotic griseofulvin inhibits the MA-sensitive PMN chemotaxis in vitro in concentrations far below those obtained in serum during antimycotic therapy . The role of the MA-sensitive chemotaxis in rheumatoid arthritis could thus be elucidated by a clinical trial of griseofulvin treatment . Griseofulvin ( n = 20 ) was tested in a randomized double-blind study versus placebo ( m = 19 ) during one year in patients with rheumatoid arthritis of mild-moderate activity . No beneficial effect of griseofulvin treatment was noted on clinical symptoms or laboratory parameters of rheumatoid arthritis . Moreover , the placebo-treated patients showed more improvement than the griseofulvin-treated patients . It is therefore suggested that the MA-sensitive chemotaxis plays a reparative role in the inflammatory lesions of rheumatoid arthritis .
{"Intervention": ["placebo", "Griseofulvin", ".", "placebo-treated", "griseofulvin", "griseofulvin-treated", "antimycotic therapy"], "Outcome": ["improvement", "beneficial effect"], "Participant": ["20", "19", "rheumatoid arthritis", "mild-moderate activity"]}