You will be shown inclusion or exclusion criteria for a clinical trial. Given these criteria, your task is to extract all unique entities of the following types: ["Observation", "Condition", "Procedure", "Drug", "Temporal", "Multiplier", "Qualifier", "Negation", "ReferencePoint", "Scope", "Value", "Mood", "Device", "Visit", "Measurement", "Person"].

Please return the output as a JSON object of the format: {"Condition" : ["breast cancer", ...], "Device" : ["ports", ...], "Drug" : ["Atenolol", ...], "Measurement" : ["blood pressure", ...], "Mood" : ["suspected", ...], "Multiplier" : ["more than two", ...], "Negation" : ["no", ...], "Observation" : ["history", ...], "Person" : ["male", ...], "Procedure" : ["surgery", ...], "Qualifier" : ["severe", ...], "ReferencePoint" : ["enrollment", ...], "Scope" : ["infection", ...], "Temporal" : ["one day", ...], "Value" : ["50%", ...], "Visit" : ["ICU", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Histologically confirmed locally advanced gastric (primary endpoint includes proximal and mid-body stomach) or esophagogastric adenocarcinoma; distal gastric (antral) adenocarcinomas are eligible for enrolment but will not be included in the primary analysis
Locally advanced disease as determined by endoscopic ultrasound (EUS) stage > primary tumor (T) 3 and/or any T, lymph nodes (N)+ disease without metastatic disease (Mx)
All patients must have diagnostic laparoscopy with diagnostic washings for cytology; both cytology positive and negative patients are eligible for enrolment, but only cytology negative patients will be included in the primary analyses; gross peritoneal disease is not eligible
Eastern Cooperative Oncology Group (ECOG) performance status =< 1
Eligible for surgery with curative intent
Absolute neutrophil count (ANC) >= 1250/ul
Hemoglobin >= 9 g/dL
Platelets >= 100,000/ul
Total bilirubin < 1.5 x upper limit of normal
Serum glutamic oxaloacetic transaminase (SGOT) and serum glutamate pyruvate transaminase (SGPT) < 2.5 x upper limit of normal for patients without liver metastases OR SGOT and SGPT < 5 x upper limit of normal for patients with liver metastases
Creatinine =< 1.5 x upper limit of normal
Measurable or non-measurable disease by Response Evaluation Criteria in Solid Tumor (RECIST) 1.1 will be allowed
Women of child-bearing potential and men must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry and for the duration of study participation, up until 30 days after final study treatment; should a woman become pregnant or suspect that she is pregnant while participating in this study, she should inform her treating physician immediately
Patients taking substrates, inhibitors, or inducers of cytochrome P450, family 3, subfamily A, polypeptide 4 (CYP3A4) should be encouraged to switch to alternative drugs whenever possible, given the potential for drug-drug interactions with irinotecan
Signed informed consent
{"Condition": ["adenocarcinomas", "adenocarcinoma gastric", "esophagogastric adenocarcinoma", "disease", "liver metastases"], "Device": [], "Drug": [], "Measurement": ["Hemoglobin", "Total bilirubin", "RECIST", "SGPT", "Creatinine", "cytology", "ECOG", "tern Cooperative Oncology Group (E formance status =\u003c", "serum glutamate pyruvate transaminase", "Absolute neutrophil count", "Platelets", "Response Evaluation Criteria in Solid Tumor", "ANC", "SGOT", "Serum glutamic oxaloacetic transaminase"], "Mood": [], "Multiplier": [], "Negation": ["without"], "Observation": [], "Person": [], "Procedure": ["laparoscopy", "endoscopic ultrasound", "surgery", "EUS", "washings for cytology"], "Qualifier": ["curative", "antral", "diagnostic", "distal gastric", "proximal stomach", "mid-body stomach", "Locally advanced", "locally advanced"], "ReferencePoint": [], "Scope": ["proximal and mid-body stomach", "SGOT and SGPT", "Serum glutamic oxaloacetic transaminase (SGOT) and serum glutamate pyruvate transaminase (SGPT)", "positive and negative", "gastric (primary endpoint includes proximal and mid-body stomach) or esophagogastric adenocarcinoma"], "Temporal": [], "Value": ["\u003e= 100,000/ul", "=\u003c 1.5 x upper limit of normal", "negative", "\u003e= 9 g/dL", "\u003c 1.5 x upper limit of normal", "positive", "\u003e= 1250/ul", "\u003e primary tumor (T) 3 and/or any T, lymph nodes (N)+ disease without metastatic disease (Mx)", "=\u003c 1", "\u003c 5 x upper limit of normal", "\u003c 2.5 x upper limit of normal", "1.1"], "Visit": []}