You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["Outcome", "Participant", "Intervention"].

Please return the output as a JSON object of the format: {"Participant" : ["patients with COPD", ...], "Intervention" : ["Atenolol", ...], "Outcome" : ["blood pressure", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

A comparison of albuterol solution nebulized versus albuterol powder given by breath activated metered dose inhaler . The goal of the present study was to compare the efficacy of nebulized vs powdered albuterol in patients with exacerbated bronchial asthma who required hospitalization . From January to May 1990 known asthmatics admitted with acute exacerbation were included by established criteria . Two groups were randomized . Group I for Albuterol powder 200 micrograms inhaled q 4 hours . Group II with Albuterol nebulized solution 2.5 mg inhaled q 4 hrs . Force Vital Capacity and Force Expiratory Volume in one second were measured with a pressure differential transducer upon admission , 30 minutes and 24-hours following therapies . Absolute FEV1 improvement was calculated . Statistical analysis was performed using student 's T-Test and Fisher 's exact Test with significance established at p > 0.01 % . Fifteen patients enrolled in both groups , two patients of group I were excluded from the statistic analysis due to refusal to continue with the therapy . Both groups were comparable with respect to sex , asthma exacerbations/year , smoking history and hospital length of stay . FVC and FEV1 were comparable also . In contrast , there were significant difference when the absolute improvement were compared . The mean +/- SE for FEV1 absolute improvement at the first 30 min was 0.42 +/- 0.08 lts for the Group I versus 0.65 +/- 0.6 lts in the Group II . In the next 24 hours , Group I was 0.16 +/- 0.2 lts versus 0.30 +/- 0.7 lts in Group II ( p > .01 ) . We conclude that although the dose equivalence of both delivery systems have not been established in our study , the nebulized solution was more effective during the first 24 hours of hospitalization than the dry powder .
{"Intervention": ["powdered albuterol", "Albuterol powder", "dry powder", "nebulized solution", "albuterol solution nebulized", "Albuterol nebulized solution", "albuterol powder", "nebulized"], "Outcome": ["Force Vital Capacity and Force Expiratory Volume", "mean +/- SE for FEV1", "FVC and FEV1", "Absolute FEV1 improvement"], "Participant": ["From January to May 1990", "exacerbated bronchial asthma who required hospitalization", "acute exacerbation", "Fifteen"]}