You will be presented with a collection of medical randomized controlled trial (RCT) reports addressing a shared clinical question -- for instance, the efficacy of a medical intervention on a disease or condition. Given the titles and abstracts of these reports, your task is to generate the conclusion of the systematic review article synthesizing the key findings. Your conclusion should be a few sentences long. In your response, include only the conclusion and no other text. The RCT reports are below.



Title 1:
Mindfulness-Based Relapse Prevention for Substance Use Disorders: A Pilot Efficacy Trial
Abstract 1:
ABSTRACT The current study is the first r and omized-controlled trial evaluating the feasibility and initial efficacy of an 8-week outpatient Mindfulness-Based Relapse Prevention ( MBRP ) program as compared to treatment as usual ( TAU ) .  Participants were 168 adults with substance use disorders who had recently completed intensive inpatient or outpatient treatment . Assessment s were administered pre-intervention , post-intervention , and 2 and 4 months post-intervention . Feasibility of MBRP was demonstrated by consistent homework compliance , attendance , and participant satisfaction . Initial efficacy was supported by significantly lower rates of substance use in those who received MBRP as compared to those in TAU over the 4-month post-intervention period . Additionally , MBRP participants demonstrated greater decreases in craving , and increases in acceptance and acting with awareness as compared to TAU . Results from this initial trial support the feasibility and initial efficacy of MBRP as an aftercare approach for individuals who have recently completed an intensive treatment for substance use disorders
No differences were observed between meditation styles .
Results suggested large effects on measures of anxiety , depression and stress , and moderate effects on measures of emotional regulation and quality of life .
As to potential mechanisms of actions , results showed large effects on measures of mindfulness and compassion , and moderate effects on measures of acceptance .
In addition , changes in mindfulness levels strongly moderated clinical effect sizes .
CONCLUSION Meditation retreats are moderately to largely effective in reducing depression , anxiety , stress and in ameliorating the quality of life of participants