You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["HealthCareActivity", "InjuryOrPoisoning", "BodySubstance", "IntellectualProduct", "AnatomicalStructure", "SpatialConcept", "Chemical", "Bacterium", "MedicalDevice", "Organization", "BiomedicalOccupationOrDiscipline", "Finding", "BiologicFunction", "Virus", "ResearchActivity", "ClinicalAttribute", "PopulationGroup", "Eukaryote", "BodySystem", "Food", "ProfessionalOrOccupationalGroup"].

Please return the output as a JSON object of the format: {"Virus": ["HIV", ...], "Bacterium": ["MRSA", ...], "AnatomicalStructure": ["Lung", ...], "BodySystem": ["CNS", ...], "BodySubstance": ["Serum", ...], "Finding": ["Headache", ...], "InjuryOrPoisoning": ["Fracture", ...], "BiologicFunction": ["Death", ...], "HealthCareActivity": ["Biopsy", ...], "ResearchActivity": ["Clinical trial", ...], "MedicalDevice": ["Lenses", ...], "SpatialConcept": ["Camps", ...], "BiomedicalOccupationOrDiscipline": ["Forensic medicine", ...], "Organization": ["WHO", ...], "ProfessionalOrOccupationalGroup": ["Provider", ...], "PopulationGroup": ["Swimmers", ...], "Chemical": ["Gold", ...], "Food": ["Rice", ...], "IntellectualProduct": ["RPAM", ...], "ClinicalAttribute": ["Biomarker", ...], "Eukaryote": ["Dogs", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Propensity Score Matched Comparison of Partial to Whole Gland Cryotherapy for Intermediate-Risk Prostate Cancer: An analysis of the COLD registry data To compare the oncological and functional outcomes of partial versus whole - gland cryotherapy for men with intermediate-risk prostate cancer. Men with intermediate-risk prostate cancer treated with primary prostate cryotherapy from 1993-2013 were selected from the Cryo On-Line Data Registry for a 1:1 matched comparison between those undergoing whole - gland and partial prostate cryotherapy (targeted-ablation, unilateral/bilateral nerve-sparing ablations). A propensity score was developed based on age, pre-biopsy serum PSA, biopsy Gleason score, clinical stage, prostate volume, neoadjuvant androgen deprivation status, year of surgery and pre-treatment potency. Outcomes were biochemical progression-free survival (BPFS) using ASTRO and Phoenix criteria, 12-month continence (strictly pad-free) and sexual function (potency sufficient for sexual intercourse). After propensity score - matching, BPFS was compared using Kaplan-Meier analysis and functional outcomes using chi-square tests. In all, 897 men were identified (731 whole - gland and 166 partial). Post-matching, 166 pairs of men were analysed (mean follow-up 31 months). The 2/5 year BPFS rate was 87.2%/76.4% for whole - gland vs. 80.7%/70.0% for partial ablation using Phoenix (p=0.26) and 72.3%/69.6% for whole gland vs. 82.1%/75.0% for partial ablation using ASTRO criteria (p=0.10). Of 164 pairs, the 12-month continence rate was similar 94.1% vs. 95.1% (p=0.803). Of 139 pairs, the 12-month rate of successful intercourse was 29.5% for whole - gland and 46.8% for partial ablation (OR 2.1, p=0.003). The incidence of post-treatment urinary retention was 6.0% and 6.6% (p=0.88) following whole - gland and partial ablation respectively and that of rectourethral fistula was 1.2% and 0% (p=0.50) Conclusion: Partial ablation results in better post-treatment sexual function compared to whole - gland ablation in men with intermediate-risk prostate cancer. We did not observe a difference in early BPFS between the two groups.
{"AnatomicalStructure": ["gland", "Gland"], "Bacterium": [], "BiologicFunction": ["oncological", "intercourse", "sexual intercourse", "sexual function", "prostate cancer", "continence", "rectourethral fistula", "Prostate Cancer"], "BiomedicalOccupationOrDiscipline": [], "BodySubstance": ["pre-biopsy serum"], "BodySystem": [], "Chemical": ["PSA"], "ClinicalAttribute": [], "Eukaryote": [], "Finding": ["urinary retention", "Intermediate-Risk", "intermediate-risk"], "Food": [], "HealthCareActivity": ["Cryotherapy", "neoadjuvant androgen deprivation", "cryotherapy", "prostate cryotherapy", "surgery", "unilateral/bilateral nerve-sparing ablations", "targeted-ablation", "follow-up", "ablation", "treated with"], "InjuryOrPoisoning": [], "IntellectualProduct": ["Cryo On-Line Data Registry", "biochemical", "chi-square tests", "COLD registry data"], "MedicalDevice": [], "Organization": [], "PopulationGroup": ["men", "Men"], "ProfessionalOrOccupationalGroup": [], "ResearchActivity": ["matching", "analysed", "analysis", "matched"], "SpatialConcept": [], "Virus": []}