You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["RNA", "CellLine", "Protein", "DNA", "CellType"].

Please return the output as a JSON object of the format: {"DNA" : ["TAL1", ...], "RNA": ["mRNAs", ...], "CellLine": ["T cells", ...], "CellType": ["monocytes", ...], "Protein": ["IL-2", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Mineralocorticoids and mineralocorticoid receptors in mononuclear leukocytes in patients with pregnancy-induced hypertension. To examine the role of mineralocorticoids in the pathophysiology of pregnancy-induced hypertension (PIH), we studied plasma aldosterone and 18-hydroxycorticosterone levels in 25 women with PIH and 25 normal pregnant women, as controls. Furthermore, we evaluated the mineralocorticoid receptor (MR) status in mononuclear leukocytes in the 2 groups. MR count was significantly (P less than 0. 0005) decreased in the PIH group (148 + /-9 binding sites / cell) compared with the control group (300 + /-17 binding sites / cell; mean + /-SEM). Plasma aldosterone in women with PIH was 281 + /-61 pmol / L; in normal pregnant women it was 697 + /-172 pmol / L (P less than 0. 025). Plasma 18-hydroxycorticosterone was also significantly (P less than 0. 025) lower (PIH, 1071 + /-149 pmol / L; controls, 1907 + /-318 pmol / L). These values were determined at the onset of clinical symptoms of PIH. These results can not be explained by receptor down-regulation due to higher levels of mineralocorticoids in PIH; a hitherto unknown mineralocorticoid may, thus, be responsible for the hypertension and altered MR status.
{"CellLine": [], "CellType": ["mononuclear leukocytes"], "DNA": [], "Protein": ["mineralocorticoid receptor", "the mineralocorticoid receptor (MR)", "mineralocorticoid receptors", "MR"], "RNA": []}