You will be shown inclusion or exclusion criteria for a clinical trial. Given these criteria, your task is to extract all unique entities of the following types: ["Observation", "Condition", "Procedure", "Drug", "Temporal", "Multiplier", "Qualifier", "Negation", "ReferencePoint", "Scope", "Value", "Mood", "Device", "Visit", "Measurement", "Person"].

Please return the output as a JSON object of the format: {"Condition" : ["breast cancer", ...], "Device" : ["ports", ...], "Drug" : ["Atenolol", ...], "Measurement" : ["blood pressure", ...], "Mood" : ["suspected", ...], "Multiplier" : ["more than two", ...], "Negation" : ["no", ...], "Observation" : ["history", ...], "Person" : ["male", ...], "Procedure" : ["surgery", ...], "Qualifier" : ["severe", ...], "ReferencePoint" : ["enrollment", ...], "Scope" : ["infection", ...], "Temporal" : ["one day", ...], "Value" : ["50%", ...], "Visit" : ["ICU", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Patients of familial cases of POF : 
Female subjects between 16 and 40 years or women older than 40 years with a cessation of ovarian function before the age of 40 years with increased levels of FSH 
Primary or secondary amenorrhea for more than three months with LH and FSH> 30mUI/ml 
No cases of fragile X syndrome in the family or blepharophimosis syndrome 
At least two cases in the family 
Origin Caucasian 
Patient signing the consent form for at least the blood sample 
Patient with Social Security 
Population Index related topics : 
The presence of cycles until the age of 40 years with proven fertility, at least one child 
Amenorrhea and FSH> 30mUI/ml according to the criteria of the index subject 
Men of the family of index case 
Population control : 
Women of Caucasian origin 
Women who had regular cycles until at least age 40 and at least one child 
Lack of land autoimmune (no history of thyroid disease or diabetes type 1) 
Woman signing the consent form for at least the blood sample
{"Condition": ["cessation of ovarian function", "Caucasian", "Amenorrhea", "fragile X syndrome", "regular cycles", "amenorrhea", "thyroid disease", "who had regular cycles until at least age 40", "autoimmune", "presence of cycles", "blepharophimosis syndrome", "diabetes type 1", "Caucasian origin"], "Device": [], "Drug": [], "Measurement": ["FSH", "LH", "levels of FSH"], "Mood": [], "Multiplier": ["At least two"], "Negation": ["no", "No"], "Observation": ["in the family", "history"], "Person": ["women", "age", "Women", "years", "Female"], "Procedure": [], "Qualifier": ["Primary", "secondary"], "ReferencePoint": ["older"], "Scope": ["thyroid disease or diabetes type 1", "Primary or secondary", "LH and FSH", "fragile X syndrome in the family or blepharophimosis syndrome"], "Temporal": ["for more than three months"], "Value": ["between 16 and 40 years", "older than 40 years", "increased", "\u003e 30mUI/ml", "before the age of 40 years", "until at least age 40", "until the age of 40 years"], "Visit": []}