You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["Outcome", "Participant", "Intervention"].

Please return the output as a JSON object of the format: {"Participant" : ["patients with COPD", ...], "Intervention" : ["Atenolol", ...], "Outcome" : ["blood pressure", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Effects of water extracts of Graptopetalum paraguayense on blood pressure , fasting glucose , and lipid profiles of subjects with metabolic syndrome . This study was aimed to investigate the effects of water extracts of Graptopetalum paraguayense ( WGP , 4 g/d ) on blood pressure , blood glucose level , and lipid profiles in subjects with metabolic syndrome ( MS ) . Participants with MS ( n = 54 ) were randomly assigned to the placebo ( n = 28 ) and WGP groups ( n = 26 ) , and the intervention was administered for 12 weeks . Systolic blood pressure ( SBP ) , diastolic blood pressure ( DBP ) , fasting glucose ( FG ) , lipid profiles ( total cholesterol ( TC ) , triglyceride ( TG ) , low density lipoprotein cholesterol ( LDL-C ) , and high density lipoprotein ( HDL-C ) ) , and antioxidant enzymes activities ( catalase ( CAT ) , superoxide dismutase ( SOD ) , and glutathione peroxidase ( GPx ) ) were measured . Forty-two subjects completed the study ( placebo , n = 19 ; WGP , n = 23 ) . FG , SBP , and LDL-C levels were significantly lower and HDL-C level and antioxidant enzymes activities ( CAT and SOD ) were significantly higher after WGP supplementation . Blood pressure , FG , and lipid profiles were significantly correlated with antioxidant enzymes activities after supplementation ( P < 0.05 ) . The present study demonstrated a significant reduction in blood pressure , blood glucose , and lipid profiles and an increase in antioxidant enzymes activities in subjects with MS after WGP supplementation . Taken together , the antioxidative capacity of WGP might exert a beneficial effect on MS . This trial is registered with ClinicalTrials.gov NCT01463748 .
{"Intervention": ["water extracts of Graptopetalum paraguayense ( WGP , 4 g/d", "WGP", "placebo", "water extracts of Graptopetalum paraguayense"], "Outcome": ["total cholesterol ( TC )", "blood pressure", "antioxidant enzymes", "SBP", "triglyceride ( TG )", "Blood pressure", "lipid profiles", "low density lipoprotein cholesterol ( LDL-C )", "LDL-C levels", "diastolic blood pressure ( DBP ) , fasting glucose ( FG )", "fasting glucose", "high density lipoprotein ( HDL-C )", "blood glucose level", "blood glucose", "FG", "HDL-C level", "Systolic blood pressure ( SBP )", "antioxidant enzymes activities"], "Participant": ["subjects with MS", "n = 54", "subjects with metabolic syndrome", "subjects with metabolic syndrome ( MS ) . Participants with MS", "Forty-two subjects", "n = 23", "n = 19"]}