You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["HealthCareActivity", "InjuryOrPoisoning", "BodySubstance", "IntellectualProduct", "AnatomicalStructure", "SpatialConcept", "Chemical", "Bacterium", "MedicalDevice", "Organization", "BiomedicalOccupationOrDiscipline", "Finding", "BiologicFunction", "Virus", "ResearchActivity", "ClinicalAttribute", "PopulationGroup", "Eukaryote", "BodySystem", "Food", "ProfessionalOrOccupationalGroup"].

Please return the output as a JSON object of the format: {"Virus": ["HIV", ...], "Bacterium": ["MRSA", ...], "AnatomicalStructure": ["Lung", ...], "BodySystem": ["CNS", ...], "BodySubstance": ["Serum", ...], "Finding": ["Headache", ...], "InjuryOrPoisoning": ["Fracture", ...], "BiologicFunction": ["Death", ...], "HealthCareActivity": ["Biopsy", ...], "ResearchActivity": ["Clinical trial", ...], "MedicalDevice": ["Lenses", ...], "SpatialConcept": ["Camps", ...], "BiomedicalOccupationOrDiscipline": ["Forensic medicine", ...], "Organization": ["WHO", ...], "ProfessionalOrOccupationalGroup": ["Provider", ...], "PopulationGroup": ["Swimmers", ...], "Chemical": ["Gold", ...], "Food": ["Rice", ...], "IntellectualProduct": ["RPAM", ...], "ClinicalAttribute": ["Biomarker", ...], "Eukaryote": ["Dogs", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Psychological Distress Is More Prevalent in Fertile Age and Premenopausal Women with PCOS Symptoms -15-yr Follow-up Polycystic ovary syndrome (PCOS) is associated with increased psychological distress; obesity and hyperandrogenism being suggested as key promoters. To investigate the prevalence of anxiety / depression and their coexistence in women with PCOS / PCOS symptoms at age s 31 and 46. The roles of obesity, hyperandrogenism and awareness of PCOS on psychological distress were also assessed. Population based follow-up. Northern Finland Birth Cohort 1966 with 15- year follow-up. At age 31 a questionnaire-based screening for oligoamenorrhea (OA) and hirsutism (H): 2188 asymptomatic (controls), 331 OA, 323 H, 125 OA + H (PCOS). 46 year old follow-up: 1576 controls, 239 OA, 231 H and 85 PCOS. Questionnaire-based screening for anxiety and depression symptoms (Hopkins Symptom Checklist-25) and previously diagnosed / treated depression at age 31 and 46. BMI, serum testosterone / free androgen index (FAI) and awareness of polycystic ovaries / PCOS on psychological distress were also assessed. Population-based prevalence of anxiety and/or depression in women with PCOS / PCOS symptoms at age s 31 and 46. Anxiety and/or depression symptoms, their coexistence and rate of depression were increased at age 31 and 46 in women with PCOS or isolated H compared with controls. High BMI or hyperandrogenism did not associate with increased anxiety or depression symptoms. The awareness of PCOS was associated with increased anxiety. Women with PCOS or isolated H present more often with anxiety and/or depression symptoms and their coexistence compared with controls. High BMI or hyperandrogenism did not provoke psychological distress in PCOS. The awareness of PCOS increased anxiety but did not associate with severe anxiety or depression.
{"AnatomicalStructure": [], "Bacterium": [], "BiologicFunction": ["anxiety", "Anxiety", "hirsutism", "OA", "PCOS", "Fertile", "hyperandrogenism", "awareness", "Premenopausal", "obesity", "H", "oligoamenorrhea", "polycystic ovaries", "depression", "Polycystic ovary syndrome"], "BiomedicalOccupationOrDiscipline": [], "BodySubstance": [], "BodySystem": [], "Chemical": [], "ClinicalAttribute": ["BMI"], "Eukaryote": [], "Finding": ["diagnosed", "asymptomatic", "Symptoms", "symptoms", "depression symptoms", "treated"], "Food": [], "HealthCareActivity": ["FAI", "follow-up", "Follow-up", "free androgen index"], "InjuryOrPoisoning": [], "IntellectualProduct": ["Hopkins Symptom Checklist-25"], "MedicalDevice": [], "Organization": [], "PopulationGroup": ["Women", "women"], "ProfessionalOrOccupationalGroup": [], "ResearchActivity": ["Questionnaire-based screening", "Population based follow-up", "questionnaire-based screening"], "SpatialConcept": ["Northern Finland"], "Virus": []}