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this was a retrospective study ( 20022010 ) that was approved by the yaound gynaeco - obstetric and paediatric hospital s ethical committee .
the data collected included age , sex , past history , delay in presentation ( duration between onset of symptoms and presentation ) , initial visual acuity , type of corneal lesion , and visual acuity at last follow - up .
cases with corneal involvement resulting from an intraocular disease , such as glaucoma , were excluded . the world health organization s definition of blindness
was used :  corrected visual acuity in the better eye of less than 1/20.1 data analysis was performed using spss statistics version 17.0 ( ibm corporation , armonk , ny , usa ) and office excel 2007 ( microsoft corporation , redmond , wa , usa ) .
corneal pathologies were seen in 168 children , giving a prevalence of 2.1% ( table 1 ) .
there were 98 males and 70 females , representing 2.6% and 1.74% , respectively , of the male and female children ( table 1 ) .
this difference was statistically significant when these proportions were compared using the chi - square test ( p = 0.0086 ) .
ages ranged from 2 weeks to 15 years , with a mean (  standard deviation ) of 7.1  4.4 years and a median of 7.0 years .
children aged 05 years and 610 years , were the most represented groups ( n = 65 for each ) ( figure 1 )
it was approximately 1 day for cases with chemical injury ; 34 days for mechanical injury , with 25.7% ( n = 18/70 ) examined within 24 hours following injury ; 52 days for infections ; and 1,827 days for dystrophies .
predisposing factors included ocular trauma in 71 cases ( 43.3% ) ; ocular surface infection , including conjunctivitis and blepharoconjunctivitis , in 15 cases ( 8.9% ) ; the use of traditional eye medicine in eight cases ( 4.8% ) ; systemic disease in two cases , including stevens  johnson syndrome and xeroderma pigmentosum ( 1.2% ) ; family history of corneal dystrophy in two cases ( 1.2% ) ; and ocular herpes in one case ( 0.6% ) .
corneal pathology was unilateral in 86.3% of cases ( n = 145 ) and bilateral in 13.7% ( n = 23 ) .
the most frequent anatomical lesions were scars of unknown origin ( 16.1% ) and superficial foreign bodies ( 14.3% ) .
the most frequent etiologies of corneal pathologies were trauma ( 81 cases [ 48.2% ] ) and infection ( 47 cases [ 28.0% ] ) ( figure 2 ) .
trauma was the most frequent etiology in all age groups , with the highest prevalence of 58.5% ( n = 38 ) occurring amongst those aged 610 years .
out of the 109 cases , 51% registered an initial visual acuity of 0.3 ( table 2 ) .
visual acuity at last follow - up was available in 24 cases ( while there was inability to cooperate in ten cases ) . visual impairment and blindness were recorded in 12 cases ( 50% ) , with one case being bilateral ( table 2 ) .
refractive errors , conjunctivitis , trauma , eyelid , and orbital pathologies are usually the most prevalent.69 srinivas reported a prevalence of 26.3% amongst 4,022 indian children aged 016 years.10 onabolu et al reported a prevalence of 42% amongst 169 children aged 016 years in the gambia.11 the difference in prevalence of corneal pathologies in this study , compared to the others , could be due to differences in the relative frequencies of specific entities . in the gambia ,
vernal keratoconjunctivitis was reported in 22.5% of cases , as compared to 6% in this study . in the study from india ,
this is due to the strategies put in place to combat vitamin a deficiency . a significantly greater proportion of male than female children were affected by corneal pathologies .
srinivas reported a similar finding.10 this can be explained by the fact that trauma is the leading cause of corneal pathologies in children ; boys are usually more involved in outdoor play than girls , and indulge in more aggressive play , which predisposes them to injury .
identifiable risk factors were detected in 58.9% of cases , with ocular trauma being the most predominant . besides direct traumatic involvement ,
trauma has been identified as a risk factor for microbial keratitis.1214 contact lens wear was the most important risk factor for microbial keratitis in taiwanese children.15 the use of contact lenses is not common in our setting .
the mean time for presentation following mechanical injury was 34.3 days ; 25.7% of cases were seen within 24 hours . in a study on ocular trauma in children in douala,16 55.5% of the children were seen within the first 24 hours . in a study from ibadan,17 nigeria ,
accessibility of hospitals , the cost of medical care , and the use of self - medication and tem could explain the delay in presentation .
however , it was noted that , compared to urban dwellers , rural dwellers used tem more frequently .
tem mainly uses plant extracts ( citrus aurantifolia , allium cepa ) and human breast milk . in a study on the use of tem by corneal ulcer patients in south india ,
prajna et al reported the use of tem in 47.7% of cases.18 the most frequent etiology was trauma ( 48.2% of cases ) .
onabolu et al also reported trauma as the most frequent etiology ( 32.4%).11 srinivas , however , reported nutritional involvement as the leading etiology , with trauma ranking fourth .
al - bdour and azab also reported a preponderance of injury in this age group.19 these are children of primary school age , who are physically more active .
the lowest proportion of infective keratitis was from the 610 years age group ( 21.3% ) , and the highest ( 48.9% ) from the 05 years age group .
the age distribution of patients with childhood microbial keratitis from southern india shows a similar trend , with 18.9% from the 610 years age group.14 in our setting , the diagnosis of infective keratitis is usually made on a clinical basis , given that most cases use eye drops containing antibiotics before presentation .
considering visual acuity at last follow - up , 50% cases suffered visual impairment and blindness .
onabolu et al reported that 45% of children with corneal diseases suffered blindness from trauma and from congenital diseases.11 congenital diseases involving the cornea were uncommon ( 3% ) .
no case was reported by srinivas in india,10 while onabolu et al reported a prevalence of 16.9% in cases from the gambia.11 the most frequent congenital eye anomalies are cataract and glaucoma.20,21 this study is limited by the high number of patients lost to follow - up , and the lack of microbiology reports for cases with suspected microbial keratitis .
although the prevalence is low , corneal pathology in children leads to poor visual outcomes .
thus , parents , childhood health care givers , teachers , and children should be educated on the prevention of ocular injury .
purposeto describe the different corneal pathologies and determine the prevalence of corneal blindness amongst children aged 015 years , seen at the ophthalmology unit of a tertiary hospital in cameroon.patients and methodsthe medical records of all patients who presented to the ophthalmic unit between 2002 and 2010 were reviewed , retrospectively . 
 the records of children aged 015 years , presenting with corneal pathologies , were further reviewed . 
 data collected included age , sex , past medical history , initial visual acuity , type of corneal lesion , and visual acuity at last follow-up.resultsof the 7,922 children seen over the study period , 168 had corneal pathologies : a prevalence of 2.1% . 
 males were more affected than females ( male to female ratio : 1.4:1 ; p = 0.008 ) . 
 the age range was from 2 weeks to 15 years ( mean age : 7.1 years ; standard deviation : 4.4 years ) . 
 the leading etiologies were trauma ( 48.2% ; n = 81 ) and infection ( 28.0% ; n = 47 ) . amongst those with available follow - up data , visual impairment and blindness occurred in 50% of the cases 
 ( n = 12 ) , with one case being bilateral.conclusiontrauma is the most frequent cause of corneal blindness in children .