You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["RNA", "CellLine", "Protein", "DNA", "CellType"].

Please return the output as a JSON object of the format: {"DNA" : ["TAL1", ...], "RNA": ["mRNAs", ...], "CellLine": ["T cells", ...], "CellType": ["monocytes", ...], "Protein": ["IL-2", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

An 11-base-pair DNA sequence motif apparently unique to the human interleukin 4 gene confers responsiveness to T-cell activation signals. We have identified a DNA segment that confers responsiveness to antigen stimulation signals on the human interleukin (IL) 4 gene in Jurkat cells. The human IL-4 gene, of 10 kilobases, is composed of four exons and three introns. A cis-acting element (P sequence) resides in the 5' upstream region; no additional DNA segments with enhancer activity were identified in the human IL-4 gene. For further mapping purposes, a fusion promoter was constructed with the granulocyte / macrophage colony-stimulating factor basic promoter containing 60 base pairs of sequence upstream from the cap site of the mouse granulocyte / macrophage colony-stimulating factor gene and various lengths of the 5' upstream sequence of the IL-4 gene. The P sequence was located between positions-79 and-69 relative to the transcription start site of the human IL-4 gene, and this location was confirmed by base-substitution mutations. The plasmids carrying multiple copies of the P sequence showed higher responsiveness to the stimulation. The binding protein (s) that recognize the P sequence of the IL-4 gene were identified by DNA-mobility-shift assays. The binding of NF (P) (a DNA binding protein that specifically recognizes the P sequence) to the P sequence was abolished when oligonucleotides carrying base substitutions were used, indicating that the NF (P) interaction is sequence-specific and that binding specificity of the protein paralleled the sequence requirements for IL-4 expression in vivo. The P sequence does not share homology with the 5' upstream sequence of the IL-2 gene, even though surrounding sequences of the IL-4 gene share high homology with the IL-2 gene. We conclude that a different set of proteins recognize IL-2 and IL-4 genes.
{"CellLine": ["Jurkat cells"], "CellType": [], "DNA": ["60 base pairs of sequence", "IL - 4 gene", "11 - base - pair DNA sequence motif", "transcription start site", "mouse granulocyte / macrophage colony - stimulating factor gene", "human interleukin 4 gene", "5\u0027 upstream region", "DNA segment", "IL - 2 and IL - 4 genes", "the P sequence", "cap site", "cis - acting element", "5\u0027 upstream sequence", "granulocyte / macrophage colony - stimulating factor basic promoter", "fusion promoter", "The P sequence", "human IL - 4 gene", "introns", "DNA segments", "IL - 2 gene", "exons", "human interleukin (IL) 4 gene", "P sequence"], "Protein": ["IL - 4", "mouse granulocyte / macrophage colony - stimulating factor", "binding protein", "DNA binding protein", "proteins", "NF (P)"], "RNA": []}