You will be presented with the full text of a biomedical research paper. Please write an abstract for this paper. Your response should include the abstract and no additional text.

Paper text:
extranodal lymphoma of mucosa - associated lymphoid tissue ( malt ) can occur throughout the body . while the gastrointestinal tract is the most common site of involvement ,
research over the past several decades has shown that cancers such as lymphomas are a genetic disease and that particular genetic mutations can lead to a syndrome of different cancer histologies .
while many organs including the pancreas , the kidneys and the central nervous system can be involved in this cancer syndrome , no known association has been established between vhl and primary pulmonary cancers . here
, we describe the presentation and management of a woman with pulmonary malt lymphoma with a past medical history significant for vhl disease .
an asymptomatic 61-year - old woman with no history of tobacco use presented to thoracic clinic with bilateral pulmonary ground glass opacities
. she had a past medical history significant for vhl disease ( type 2b exon iii mutation ) .
manifestations of her vhl syndrome included a pancreatic neuroendocrine tumor , bilateral pheochromocytomas , spinal hemangioblastomas and benign renal cystic lesions . upon surveillance computed tomography ( ct ) imaging of the chest ,
a lesion in the right upper lobe became more solid - appearing ( fig . 
1a ) . positron emission tomography ( pet ) imaging revealed that the lesion was also pet - avid with a maximum standardized uptake value ( suv ) of 7.7 ( fig . 
1b ) . 
 figure  1:(a ) ct chest revealing right upper lobe solid lesion .
( b ) pet scan of the chest revealing pet - avid right upper lobe lesion .
( b ) pet scan of the chest revealing pet - avid right upper lobe lesion .
a percutaneous biopsy was performed , but the cytology report was equivocal , demonstrating rare atypical cells in a background of blood and histiocytes .
as this lesion was concerning for a primary lung cancer , a video - assisted thoracoscopic ( vats ) right upper lobectomy was performed in an effort to achieve a complete oncologic resection .
the operation was carried out in the usual manner , including isolating and dividing the superior pulmonary vein , artery and bronchus with an endo - gastrointestinal anastomosis stapling device .
furthermore , a lymph node dissection , including specimens from stations 10r and 4r , was performed .
the right upper lobe was 194 g and measured 12.5  11  3 cm . within it , a 3  2.5  2.5 cm yellow  tan mass consistent with the area of concern on imaging contained necrotic and hemorrhagic nodules .
this was initially diagnosed as a reactive process ; but because of the density of the lymphocytic infiltrate and the presence of a mass , molecular studies were performed .
these tests revealed a clonal b - cell process consistent with a diagnosis of extranodal marginal zone lymphoma of the malt type . 

figure  2:(a ) station 10r lymph node with hematoxylin and eosin ( h&e ) stain under 20 magnification with many lymphocytes apparent .
( b ) station 10r lymph node with cd-20 staining revealing b cells within a reactive germinal center under 20 magnification .
( c ) station 10r lymph node with cd-3 staining demonstrating t cells surrounding a reactive germinal center under 20 magnification . 

figure  3:right upper lobe lung mass under 20 magnification with staining for cd-20 and cd-3 showing a dense lymphoplasmacytic infiltrate mainly consisting of b cells ( a ) and fewer t cells ( b ) .
( a ) station 10r lymph node with hematoxylin and eosin ( h&e ) stain under 20 magnification with many lymphocytes apparent .
( b ) station 10r lymph node with cd-20 staining revealing b cells within a reactive germinal center under 20 magnification .
( c ) station 10r lymph node with cd-3 staining demonstrating t cells surrounding a reactive germinal center under 20 magnification .
right upper lobe lung mass under 20 magnification with staining for cd-20 and cd-3 showing a dense lymphoplasmacytic infiltrate mainly consisting of b cells ( a ) and fewer t cells ( b ) .
she remained in the hospital for 9 days following her surgery secondary to a prolonged air leak , which subsided without intervention .
postoperatively , she will be monitored by both the thoracic surgery and thoracic oncology services for recurrence .
cancer genetic syndromes occur when a single genetic mutation leads to a spectrum of cancer histologies in the same patient .
vhl disease is an example of one such syndrome that is inherited in an autosomal dominant fashion and affects 1 per 35 000 people .
inactivation of the vhl tumor suppressor gene via genetic mutations can lead to the development of several different malignant and benign tumors including renal cell carcinoma , pancreatic neuroendocrine tumors , pheochromocytoma , retinal angiomas and spinal hemangioblastomas .
primary lung lymphoma ( pll ) is defined as biopsy - proven lymphoma in the lung without the evidence of extra - pulmonary involvement   and accounts for < 1% of all lung tumors .
the most common of the plls is malt lymphoma , which is a low - grade b - cell lymphoma .
the diagnosis of pulmonary malt lymphoma can be mistaken for a reactive process , so additional studies such as molecular analyses to identify clonal populations of lymphocytes may be necessary to confirm the diagnosis .
because of the rarity of the disease , there are no definitive treatment guidelines , but surgery has been shown to be beneficial in patients with localized disease .
there is no known association between pulmonary malt lymphoma and vhl disease to date , but case reports have documented patients with vhl disease who developed other primary lung cancers including adenocarcinomas   and carcinoids .
furthermore , loss of heterozygosity of the vhl gene region has been reported in up to 83% of non - small cell lung cancer specimens .
however , given the limited number of reports , it is difficult to find a definitive association between vhl disease and primary lung cancers , including pulmonary malt lymphoma . to our knowledge
, this is the first reported case of a patient with vhl disease who developed a pulmonary malt lymphoma .
whereas the initial pathology report suggested a reactive process , further analysis was consistent with this tumor pathology .
surgeons and physicians in general need to have a high index of suspicion when managing patients with vhl disease and other cancer genetic syndromes in general .
furthermore , increased awareness of these tumor types in patients with familial syndromes may help guide surgical intervention in the future , as a lobectomy may not be necessary , and a non - anatomic wedge resection may be adequate .
a 61-year - old female with a past medical history significant for von hippel  lindau ( vhl ) syndrome presented with multiple bilateral pulmonary lesions found on surveillance computed tomography scan . 
 positron emission tomography demonstrated avidity in a lesion in the right upper lobe . 
 after an equivocal biopsy , a lobectomy via a thoracoscopic approach was performed as this lesion was concerning for a primary lung cancer . 
 pathology revealed a diagnosis of pulmonary mucosa - associated lymphoid tissue ( malt ) lymphoma . to our knowledge , this is the first reported case of a pulmonary malt lymphoma in a patient with vhl .