You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["Outcome", "Participant", "Intervention"].

Please return the output as a JSON object of the format: {"Participant" : ["patients with COPD", ...], "Intervention" : ["Atenolol", ...], "Outcome" : ["blood pressure", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Prognostic significance and beneficial effect of diltiazem on the incidence of early recurrent ischemia after non-Q-wave myocardial infarction : results from the Multicenter Diltiazem Reinfarction Study . Of 576 patients with non-Q-wave acute myocardial infarction enrolled in the Diltiazem Reinfarction Study , 246 ( 43 % ) had 1 or more episodes of angina at rest or with minimal effort during 10.5 days of treatment with either diltiazem ( 90 mg every 6 hours ) or placebo . Reinfarction ( 12.2 % vs 3.6 % , p less than 0.0001 ) or death ( 6.1 % vs 1.5 % , p = 0.003 ) was more likely to occur within 2 weeks of randomization in patients with postinfarction angina than in those without angina . Based on serial electrocardiographic data , 115 of the 246 patients with angina had transient ST-T changes and 131 did not . Comparison of the 14-day event rates in these 2 groups showed that the 115 patients with electrocardiographic evidence of ischemia had a higher frequency of reinfarction ( 20 % vs 5.3 % , p less than 0.001 ) , more extensive damage as assessed by peak MB-creatine kinase levels ( 91 +/- 76 vs 37 +/- 19 IU/liter , p = 0.059 [ Wilcoxon rank sum ] ) and a higher mortality rate ( 11.3 % vs 1.5 % , p = 0.001 ) . Angina associated with transient ST-T changes occurred in 70 of the 289 patients in the placebo group but in only 45 of the 287 patients in the diltiazem group -- a 28 % reduction in cumulative life-table incidence ( p = 0.0103 [ 2-tail , log rank ] ; 95 % confidence interval , 9.3 to 53.8 % ) . It is concluded that patients with early postinfarction angina are at increased risk of reinfarction and death , and angina associated with transient electrocardiographic changes identified a very high risk subset . This subset appeared to have a larger area of viable but jeopardized myocardium and benefited from prophylactic therapy with diltiazem .
{"Intervention": ["diltiazem", "placebo"], "Outcome": ["death", "reinfarction", "transient ST-T changes", "risk of", "angina associated with transient electrocardiographic", "jeopardized myocardium", "beneficial effect", "Angina", "Prognostic significance", "early recurrent ischemia", "ST-T", "higher mortality rate", "Reinfarction", "cumulative life-table incidence", "viable", "peak MB-creatine kinase levels", "changes", "extensive damage"], "Participant": ["early recurrent ischemia", "early postinfarction angina", "non-Q-wave acute myocardial infarction", "576"]}