You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["HealthCareActivity", "InjuryOrPoisoning", "BodySubstance", "IntellectualProduct", "AnatomicalStructure", "SpatialConcept", "Chemical", "Bacterium", "MedicalDevice", "Organization", "BiomedicalOccupationOrDiscipline", "Finding", "BiologicFunction", "Virus", "ResearchActivity", "ClinicalAttribute", "PopulationGroup", "Eukaryote", "BodySystem", "Food", "ProfessionalOrOccupationalGroup"].

Please return the output as a JSON object of the format: {"Virus": ["HIV", ...], "Bacterium": ["MRSA", ...], "AnatomicalStructure": ["Lung", ...], "BodySystem": ["CNS", ...], "BodySubstance": ["Serum", ...], "Finding": ["Headache", ...], "InjuryOrPoisoning": ["Fracture", ...], "BiologicFunction": ["Death", ...], "HealthCareActivity": ["Biopsy", ...], "ResearchActivity": ["Clinical trial", ...], "MedicalDevice": ["Lenses", ...], "SpatialConcept": ["Camps", ...], "BiomedicalOccupationOrDiscipline": ["Forensic medicine", ...], "Organization": ["WHO", ...], "ProfessionalOrOccupationalGroup": ["Provider", ...], "PopulationGroup": ["Swimmers", ...], "Chemical": ["Gold", ...], "Food": ["Rice", ...], "IntellectualProduct": ["RPAM", ...], "ClinicalAttribute": ["Biomarker", ...], "Eukaryote": ["Dogs", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Preliminary Randomized Controlled Trial of Habit Reversal Training for Treatment of Hair Pulling in Youth This study evaluated the treatment efficacy of habit reversal training (HRT) relative to treatment as usual (TAU) for children and adolescents aged 7-17 years with a primary diagnosis of trichotillomania (TTM). An initial assessment consisting of semistructured interviews and rating scales was conducted. Participants (N = 40, 85% female) meeting diagnostic criteria for TTM were randomized to either 8 weekly sessions of HRT by trained therapists or 8 weeks of TAU. One week after the final HRT session or final TAU week, patients completed a posttreatment assessment, followed by 1- and 3- month follow-up assessments. All assessments were conducted by a trained rater who was blinded to treatment condition. The group by time analysis of variance yielded a significant interaction on the National Institute of Mental Health - Trichotillomania Severity Scale Total Score (F1,38 = 16.47, p < 0.001, η(2)p = 0.30). The mean score decreased from 12.67 ± 4.60 at baseline to 5.62 ± 4.38 at posttreatment in the HRT group (t20 = 5.99, p < 0.001, d = 1.31), whereas the TAU group changed from 10.42 ± 4.35 to 9.32 ± 4.11 (t18 = 1.34, p = 0.20, d = 0.31). The Massachusetts General Hospital-Hair Pulling Scale Total Score decreased from 15.14 ± 3.86 at baseline to 7.14 ± 5.54 at posttreatment in the HRT group (t20 = 6.16, p < 0.001, d = 1.34); the TAU group changed from 14.16 ± 4.51 to 12.26 ± 4.34 (t18 = 1.50, p = 0.15, d = 0.34). On the Clinical Global Impressions-Improvement, 16/21 participants (76%) were rated as treatment responders in the HRT group versus 4/19 (21%) in the TAU group (χ(2) = 12.13, p < 0.001, V = 0.55). At 1- month follow-up, 10-12 treatment responders who completed the assessment maintained improvement. At 3- month follow-up, six of eight maintained improvement. HRT can be an effective treatment for TTM in youth.
{"AnatomicalStructure": [], "Bacterium": [], "BiologicFunction": ["TTM", "Hair Pulling", "trichotillomania"], "BiomedicalOccupationOrDiscipline": [], "BodySubstance": [], "BodySystem": [], "Chemical": [], "ClinicalAttribute": [], "Eukaryote": [], "Finding": [], "Food": [], "HealthCareActivity": ["Treatment", "assessment", "posttreatment assessment", "evaluated", "assessments", "follow-up", "posttreatment", "Habit Reversal Training", "treatment", "HRT", "habit reversal training"], "InjuryOrPoisoning": [], "IntellectualProduct": ["Clinical Global Impressions-Improvement", "diagnostic criteria"], "MedicalDevice": [], "Organization": ["National Institute of Mental Health"], "PopulationGroup": ["participants", "responders", "group", "Participants"], "ProfessionalOrOccupationalGroup": ["rater"], "ResearchActivity": ["study", "diagnosis", "blinded", "Randomized Controlled Trial", "randomized"], "SpatialConcept": [], "Virus": []}