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Paper text:
until recently , the femoral approach was the preferably used method in interventional cardiology for diagnostics and therapy of coronary artery disease .
it has been perceived as being easy and facilitating quick access with relatively low risk . due to the results of latest studies ,
the use of the radial approach not only reduced incidence of local and general operation - related complications , but also proved to be preferred by patients [ 13 ] . despite the almost unequivocal results concerning the selection of the vessel approach , radial access continues to have its detractors .
the most common arguments brought up are the relatively large proportion of permanent radial artery occlusions following surgery and the need to learn a new method that is more difficult for the operator than the radial approach is .
thus , the largest opposition to this access is encountered in surgeons experienced in the femoral approach .
the analysis was performed in the department during the transition period from the femoral to the radial approach .
the aim of this paper was a retrospective comparison of safety between the femoral and radial approaches during coronal arterial angiography procedures conducted in patients hospitalized between the years 2008 and 2009 at the hemodynamics laboratory in the department of invasive cardiology in the military institute of medicine .
the analysis covered diagnostic and therapeutic coronary artery procedures in year 2008 when the femoral approach was preferred ( 90 patients ) and in the year 2009 when the radial approach was introduced ( 114 patients ) . in 2008 , all patients were submitted to the femoral approach but in the year 2009 , eleven ( 11 ) patients were subjected to the femoral approach whereas 103 to the radial approach .
time intervals ( 0102.2008 and 0405.2009 ) were selected accordingly to obtain comparable groups with respect to the number of patients with the femoral approach ( fa ) and the radial approach ( ra ) .
two patients were excluded from the fa group because of a previous , ineffective radial approach procedure and as a result the access was changed to femoral .
the opposite process ( a shift from the radial to the femoral approach ) was not observed . in the end ,
continuous variables are expressed as medians with 1 to 3 percentile and qualitative variables as percentages .
the normality of each continuous variable was at first tested with the shapiro - wilk w test . because there were non - normal variables in further analyses , nonparametric
basic demographic data , the type of procedure , and indications to coronary intervention were assessed ( table 1 ) and no differences between fa and ra groups were observed .
groups of patients were also analyzed with respect to ionizing radiation exposure , the volume of administered contrast agent , and procedure - related complications , which were divided into hemorrhagic ( major bleedings ) and local ( false aneurysm and large hematomas ) .
continuous variables are expressed as medians with 1 to 3 percentile and qualitative variables as percentages .
the normality of each continuous variable was at first tested with the shapiro - wilk w test . because there were non - normal variables in further analyses , nonparametric , two - sided tests were used .
basic demographic data , the type of procedure , and indications to coronary intervention were assessed ( table 1 ) and no differences between fa and ra groups were observed .
groups of patients were also analyzed with respect to ionizing radiation exposure , the volume of administered contrast agent , and procedure - related complications , which were divided into hemorrhagic ( major bleedings ) and local ( false aneurysm and large hematomas ) .
the analysis shows that there are differences in the volumes of contrast used during between the fa and ra groups ( figure 1 ) but no differences recorded in ionizing radiation dose ( figure 2 ) .
use of contrast agent was greater during the radial approach than in the femoral approach in each studied group .
patients were also compared with regard to complications , but no statistically significant differences were observed between the groups ( table 3 ) .
there was , however , a tendency to an increased number of complications in the fa group , accompanied with a borderline value using the fisher exact test ( p=0.058 ) .
it is noteworthy that despite there being no statistical differences in the ra group , no complications were reported , whereas in the fa group they did occur ( table 3 ) .
the aim of this work was to demonstrate the benefits of the radial approach in comparison to the femoral approach for patients with coronary interventions ( diagnostic or therapeutic ) .
we selected from among factors which can be easily assessed by retrospective analysis and contribute to patient benefit in terms of the volume of applied contrast agent , ionizing radiation dose , and incidence of complications . in short - term observations ,
in contrast , in patients requiring multiple ionizations for diagnostic and therapeutic purposes , some skin and hematopoietic disturbances were reported even in a short observation period . moreover
, the risk of carcinogenic activity of ionizing radiation can not be excluded , as was proven in patients submitted to ct diagnostics . between the compared groups ,
no statistically significant difference in absorbed ionizing radiation dose was found . in recently published studies ,
similar results were obtained by the stemi - radial team , who admittedly analyzed the time of fluoroscopy , not the radiation dose ; nonetheless , were no differences between groups .
however , there are studies which demonstrate a small but statistically significant difference in radiation dose , which was smaller in the femoral approach [ 3 , 5 ] .
contrast agent is crucial for radio - diagnostics because quality of obtained pictures depends on volume and quality of contrast agent .
however , it should be remembered that some complications such as cin ( contrast - induced nephropathy ) and hypersensitive reactions , are connected with excessive volume of contrast agent . in previous papers
, there were no differences in volume of contrast agent in terms of the vessel approach used   or the volume was greater in the radial approach .
our results are particularly interesting , because contrary to previous reports , they indicate that the volume of contrast agent is statistically greater in the radial approach procedure
. it corresponds , however , to the results of  the learning curve  in radial approach procedures .
please note that the period of 20082009 was a time when the department shifted from the femoral to the radial approach .
as mentioned previously , in 2008 most of the procedures were performed using the femoral approach . in the year 2009 , this relationship was reversed .
thus , in 2009 , our surgeons passed through consecutive stages of  the learning curve  .
most published reports were derived from sites with a long - standing use of and experience in the femoral and radial approaches .
this could explain the divergence between the aforementioned large studies and the presented retrospective analysis . in this study ,
the advantage of the radial approach with regard to peri - procedural complications was not proven .
it could be attributed to progress in intervention cardiology ( i.e. , new devices and new techniques ) which reduces the risk of complications regardless of the vessel approach used . with regard to the observed tendency
, a larger number of patients would be necessary to demonstrate the advantage of radial access .
therefore , large clinical studies demonstrate advantages of the radial approach . during the conducted analysis
, single defined complications were observed in the fa group but not in the ra group .
the increasingly frequently used and patient - preferred radial approach is as safe as the classic femoral approach with regard to peri - procedural complications and it does not increase patient exposure to ionizing radiation . at sites where the radial approach is not routine , the risk of larger contrast agent volume usage increases .
thus , in patients at risk of cin or who have renal deficiency or hypersensitivity to the contrast agent in their medical history , the classical femoral approach should be recommended .
backgroundthe femoral approach has been the preferably used access in interventional cardiology as well for coronary diagnostics as for percutaneous coronary intervention , being perceived as easy and facilitating quick access with relatively low risk . due to the results of the latest studies , 
 however , the radial approach has become increasingly popular . 
 the aim of this study was a safety analysis of cardiological interventional procedures ( i.e. , coronarography and pci ) according to the vessel approach.material/methodsthe 204 coronary interventions done in our department of interventional cardiology were retrospectively analyzed . 
 all the procedures were classified according to femoral or radial access . 
 the incidence of local complications ( e.g. , major bleedings and hematomas ) was assessed as well as the volume of contrast agent administered during the procedure and the radiation dose.resultsit has been shown that radial approach , which is obviously more comfortable for patients , reduces the risk of local complications ( 0 vs. 2.97% and 0 vs. 3.96% ) and does not lead to increased radiation exposure ( p=0.88 ) . 
 however , there could be a larger volume of contrast agent administered ( p=0.029 ) , which in some cases could increase the risk of contrast - induced nephropathy.conclusionsthe radial approach should be recommended as a first choice because it is safer than the classical femoral approach , but one must be cautious in choosing radial approach patients with renal insufficiency .