You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["Outcome", "Participant", "Intervention"].

Please return the output as a JSON object of the format: {"Participant" : ["patients with COPD", ...], "Intervention" : ["Atenolol", ...], "Outcome" : ["blood pressure", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Short-term effects of systemic antibiotics during periodontal healing . OBJECTIVES To investigate the short-term effects of nonsurgical therapy ( scaling and root planing , SRP ) on the subgingival microbiota in chronic ( CP ) and aggressive ( AP ) periodontal disease . METHOD AND MATERIALS Ninety-seven CP and AP subjects underwent full-mouth SRP on 2 consecutive days . AP patients were randomly assigned to either receive systemic metronidazole plus amoxicillin ( AP+AB ) or were treated mechanically alone ( AP ) . Pathogens were identified with 16S rRNA oligodeoxynucleotide probes and dot-blot hybridization before and at days 2 , 3 , 4 , 7 , 10 , and 21 of healing . CP subjects were treated by scaling and root planing along with placebo tablets . RESULTS Initially , AP cell counts were 69.9- ( Porphyromonas gingivalis ) , 10.2- ( Aggregatibacter actinomycetemcomitans ) , 5.7- ( Tannerella forsythia ) , and 3.3-fold ( Prevotella intermedia ) enhanced compared to CP cell counts . Following SRP , immediate elimination occurred in single individuals of all three treatment groups at day 2 . After SRP plus antibiotic therapy ( AP+AB ) , the prevalence scores dropped beyond the levels of AP and CP , beginning at day 7 , and remained low until day 21 ( P =or < .05 ) . Clinical healing statistically benefited from SRP with no differences among the three treatment groups . CONCLUSION Nonsurgical therapy resulted in both a suppression and early elimination of single taxa immediately after completion of active treatment . Systemic antibiotics significantly accelerate the suppression of the periodontal microflora , but have limited effect on the elimination of target isolates during healing .
{"Intervention": ["systemic metronidazole plus amoxicillin ( AP+AB )", "antibiotics", "treated mechanically alone ( AP )", "placebo tablets .", "SRP plus antibiotic therapy"], "Outcome": ["effects", "AP cell counts", "16S rRNA oligodeoxynucleotide probes and dot-blot hybridization", "CP", "Clinical healing", "AP", "SRP plus antibiotic therapy", "periodontal microflora", "single taxa"], "Participant": ["periodontal healing .", "nonsurgical therapy ( scaling and root planing , SRP ) on the subgingival microbiota in chronic ( CP ) and aggressive ( AP ) periodontal disease ."]}