You will be shown inclusion or exclusion criteria for a clinical trial. Given these criteria, your task is to extract all unique entities of the following types: ["Observation", "Condition", "Procedure", "Drug", "Temporal", "Multiplier", "Qualifier", "Negation", "ReferencePoint", "Scope", "Value", "Mood", "Device", "Visit", "Measurement", "Person"].

Please return the output as a JSON object of the format: {"Condition" : ["breast cancer", ...], "Device" : ["ports", ...], "Drug" : ["Atenolol", ...], "Measurement" : ["blood pressure", ...], "Mood" : ["suspected", ...], "Multiplier" : ["more than two", ...], "Negation" : ["no", ...], "Observation" : ["history", ...], "Person" : ["male", ...], "Procedure" : ["surgery", ...], "Qualifier" : ["severe", ...], "ReferencePoint" : ["enrollment", ...], "Scope" : ["infection", ...], "Temporal" : ["one day", ...], "Value" : ["50%", ...], "Visit" : ["ICU", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Female 
Age ≥18 years 
Patients with a lesion > 0.5 cm in largest diameter size, initially scored BI-RADS® 3, 4a, 4b or 4c in B-mode ultrasound 
Informed consent about histological examination (core cut biopsy (CCB), vacuum-assisted biopsy (VAB), fine needle aspiration (FNA) or surgery) has already been given in the course of clinical routine 
Signed informed consent of study participation
{"Condition": ["lesion"], "Device": [], "Drug": [], "Measurement": ["BI-RADS\u00ae", "largest diameter size"], "Mood": [], "Multiplier": [], "Negation": [], "Observation": [], "Person": ["Female", "Age"], "Procedure": ["B-mode ultrasound", "fine needle aspiration (FNA)", "vacuum-assisted biopsy (VAB)", "surgery", "histological examination", "core cut biopsy (CCB)"], "Qualifier": [], "ReferencePoint": [], "Scope": ["core cut biopsy (CCB), vacuum-assisted biopsy (VAB), fine needle aspiration (FNA) or surgery"], "Temporal": [], "Value": ["\u003e 0.5 cm", "3, 4a, 4b or 4c", "\u226518 years"], "Visit": []}