You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["Outcome", "Participant", "Intervention"].

Please return the output as a JSON object of the format: {"Participant" : ["patients with COPD", ...], "Intervention" : ["Atenolol", ...], "Outcome" : ["blood pressure", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Financial and quality-of-life burden of dysfunctional uterine bleeding among women agreeing to obtain surgical treatment . PURPOSE In this study , we sought to 1 ) describe elements of the financial and quality-of-life burden of dysfunctional uterine bleeding ( DUB ) from the perspective of women who agreed to obtain surgical treatment ; 2 ) explore associations between DUB symptom characteristics and the financial and quality-of-life burden ; 3 ) estimate the annual dollar value of the financial burden ; and 4 ) estimate the most that could be spent on surgery to eliminate DUB symptoms for which medical treatment has been unsuccessful that would result in a $ 50,000/quality-adjusted life-year incremental cost-effectiveness ratio . METHODS We collected baseline data on DUB symptoms and aspects of the financial and quality-of-life burden for 237 women agreeing to surgery for DUB in a randomized trial comparing hysterectomy with endometrial ablation . Measures included out-of-pocket pharmaceutical expenditures , excess expenditures on pads or tampons , the value of time missed from paid work and home management activities , and health utility . We used chi2 and t tests to assess the statistical significance of associations between DUB characteristics and the financial and quality-of-life burden . The annual financial burden was estimated . RESULTS Pelvic pain and cramps were associated with activity limitations and tiredness was associated with a lower health utility . Excess pharmaceutical and pad and tampon costs were $ 333 per patient per year ( 95 % confidence interval [ CI ] , $ 263- $ 403 ) . Excess paid work and home management loss costs were $ 2,291 per patient per year ( 95 % CI , $ 1847- $ 2752 ) . Effective surgical treatment costing $ 40,000 would be cost-effective compared with unsuccessful medical treatment . CONCLUSION The financial and quality-of-life effects of DUB represent a substantial burden .
{"Intervention": ["financial and quality-of-life effects", "financial and quality-of-life burden", "Financial and quality-of-life burden", "baseline data on DUB symptoms and aspects of the financial and quality-of-life burden"], "Outcome": ["tiredness", "paid work and home management loss costs", "cost-effective", "Pelvic pain and cramps", "health utility", "Effective surgical treatment", "out-of-pocket pharmaceutical expenditures", "excess expenditures on pads or tampons", "the value of time missed from paid work and home management activities", "lower health utility", "activity limitations", "Excess pharmaceutical and pad and tampon costs"], "Participant": ["dysfunctional uterine bleeding among women agreeing to obtain surgical treatment ."]}