You will be shown the abstract of a medical clinical trial report. Your task is to extract all the findings from this report into a JSON array. Each finding should contain the following five elements:

- Intervention: The medical intervention being tested. This should be a text span copied from the input passage.
- Comparator: The baseline against which the intervention is being evaluated. This should be a text span copied from the input passage. If no comparator is reported, set to `null`.
- Outcome: The medical outcome whose effect is being measured. This should be a text span copied from the input passage.
- Effect: The effect of the intervention on the outcome, relative to the comparator. The effect should be one of the following three values: ("significantly increased", "significantly decreased", "no significant difference").
- Evidence: The evidence for the effect. This should be a text span copied from the input passage.

Please format your output as a JSON array. Each entry in the output should be an array containing the 5 elements listed above, in the following order: [<intervention>, <comparator>, <outcome>, <effect>, <evidence>].

For example, an output with two findings might read:
```
[["aspirin", "placebo", "headache severity", "significantly decreased", "Mean headache severity was significantly decreased in the aspirin group compared to the placebo group (p < 0.05)."], ["aspirin", "placebo", "weight loss", "no significant difference", "We did not observe any difference in weight loss between the group given aspirin relative to the control group"]]
```

There are 5 finding(s) in the abstract below. Please extract them. Output only the JSON array with these 5 findings. Do not include any additional text.

Abstract:
ABSTRACT: Objectives were to evaluate effects of (1) repetitive arthrocentesis on biomarkers of inflammation (prostaglandin E2, PGE2) and aggrecan synthesis (chondroitin sulfate-846; CS) in synovial fluid (SF); (2) exercise and superoxide dismutase (SOD) supplementation on biomarkers of inflammation, antioxidant status, and aggrecan synthesis, in horses. Preliminary trial. Standardbreds underwent four arthrocentesis procedures within 48 h and exhibited elevated CS and no changes in PGE2. Exercise trial. this randomized crossover design used twelve Standardbred mares which received either treatment (3000 IU d−1 oral SOD powder) or placebo (cellulose powder) for 6 wks which culminated with them running a repeated sprint exercise test (RSET). Samples were collected before (PRE), during (PEAK), and following exercise (POST). Exercise resulted in increased (P < 0.05) antioxidant defenses including erythrocyte SOD, total glutathione, glutathione peroxidase, gene transcripts for interferon-gamma, interleukin-10, and interleukin-1β in blood, and decreased plasma nitric oxide. Exercise increased (P < 0.05) SF CS and adjusted-PGE2, and higher (P < 0.05) CS and PGE2 were found in hock versus carpus joints. No treatment effects were detected. Results suggest normal adaptive responses likely due to exercise-induced tissue microdamage and oxidative stress. Additional research is needed to identify benefit(s) of SOD supplementation in horses.

Findings:
[["exercise", "no exercise", "erythrocyte SOD, total glutathione, glutathione peroxidase, gene transcripts for interferon-gamma, interleukin-10, and interleukin-1? in blood", "significantly increased", "Exercise resulted in increased (P \u003c 0.05) antioxidant defenses including erythrocyte SOD, total glutathione, glutathione peroxidase, gene transcripts for interferon-gamma, interleukin-10, and interleukin-1\u03b2 in blood, and decreased plasma nitric oxide."], ["exercise", "no exercise", "plasma nitric oxide", "significantly decreased", "Exercise resulted in increased (P \u003c 0.05) antioxidant defenses including erythrocyte SOD, total glutathione, glutathione peroxidase, gene transcripts for interferon-gamma, interleukin-10, and interleukin-1\u03b2 in blood, and decreased plasma nitric oxide."], ["exercise", "no exercise", "chondroitin sulfate-846 (CS) in synovial fluid (SF) and adjusted-PGE2, ", "significantly increased", "Exercise increased (P \u003c 0.05) SF CS and adjusted-PGE2, and higher (P \u003c 0.05) CS and PGE2 were found in hock versus carpus joints."], ["3000 IU d?1 oral superoxide dismutase (SOD) powder for 6?wks - treatment group (TRT)", "placebo (cellulose powder) for 6?wks", "erythrocyte SOD, total glutathione, glutathione peroxidase, gene transcripts for interferon-gamma, interleukin-10, and interleukin-1? in blood, and decreased plasma nitric oxide.", "no significant difference", "There were no TRT effects detected for any parameter measured (P \u003e 0.05)."], ["3000 IU d?1 oral superoxide dismutase (SOD) powder for 6?wks - treatment group (TRT)", "placebo (cellulose powder) for 6?wks", "erythrocyte SOD, total glutathione, glutathione peroxidase, gene transcripts for interferon-gamma, interleukin-10, and interleukin-1? in blood, and decreased plasma nitric oxide.", "no significant difference", "No treatment effects were detected."]]