You will be presented with the full text of a biomedical research paper. Please write an abstract for this paper. Your response should include the abstract and no additional text.

Paper text:
formal ethical approval from a medical ethical committee was not required for this research because it was carried out as part of the public health monitoring and evaluation of contacts and did not entail subjecting participants to medical treatment . from the onset of symptoms in the 2 mers - cov patients
( may 1 ) until their discharge from the hospital ( june 5 ) , they came into contact with 131 persons .
of these , 78 had unprotected exposure ( defined as > 15 min of face - to - face contact without wearing personal protective equipment ) and 53 had protected exposure ( defined as providing care while wearing adequate personal protection at all times ) . of the unprotected contacts , 29 were members of the patients travel group , 17 were aircraft contacts , and 32 were contacts in the netherlands before hospital admission ( 28 relatives plus 4 persons at a general medical practice and the hospital emergency department , including 1 health care worker ) .
the travel group had traveled with the 2 confirmed case - patients through saudi arabia during april 26may 10 and had direct contact with them .
four travelers reported direct contact with dromedary camels , 11 consumed unpasteurized camel milk , and 4 visited a local hospital .
one traveler accompanied 1 case - patient to 4 different hospitals and shared a hotel room with both case - patients ( 7 ) .
the aircraft contacts had been seated within 3 rows of the case - patients on the return flight .
all contacts were asked to take their temperature twice a day and report any episode of fever ( temperature > 38c ) , cough , diarrhea , or dyspnea for 14 days following their last possible exposure to the case - patients .
throat swabs were obtained from contacts on days 7 and 14 postexposure , and serum samples were drawn on days 7 and 21 postexposure ( technical appendix ) .
throat swab samples from 1 relative contact were unavailable ; a second serum sample was missing from 7 relatives , 3 aircraft contacts , and 1 travel contact ( a woman who had had no contact with animals , had not visited a hospital , and had no concurrent conditions ) .
eight contacts who reported symptoms ( 7 unprotected and 1 protected ) were sampled immediately after onset of symptoms . mers - cov reverse transcription pcr ( rt - pcr ) was performed on paired throat swabs from 106 ( 81% ) and serologic analysis on paired serum samples from 99 ( 76% ) of the 131 contacts ( table 1 ) .
pcr did not detect mers - cov rna from any throat swab or serum samples , and mers - cov 
specific igg responses were absent in serum samples tested ( 8) ( table 1 ) .
all specimens obtained from the symptomatic contacts tested negative by rt - pcr and analysis of paired serum samples for mers - cov .  
other contacts were those who had contact with the case - patients after their return to the netherlands : 28 relatives , plus 4 persons at a general medical practice and the hospital emergency department , including 1 health care worker .
all contacts also received an online questionnaire containing questions about demographics , type of contact , quality of information received , perceived severity and vulnerability , feelings of anxiety , interference of the measures with daily life , and knowledge of the measures and travel advice ( technical appendix ) . to evaluate the effect of monitoring , we used the revised impact of event scale ( ies - r ) , a validated questionnaire designed to assess current subjective distress for a specific traumatic life event ( 9 )
. the ies - r contains 22 items divided into 3 subscales : avoidance ( e.g. , avoidance of feelings ) , intrusion ( e.g. , nightmares ) and hyperarousal ( e.g. , anger ) .
the mean score on 3 subscale domains indicates the level of distress experienced ( 9 ) .
mean scores of unprotected contacts were compared with those of protected contacts by a wilcoxon rank - sum test or t - test .
a total subjective stress ies - r score with a maximum score of 88 ( likert scale of 04 [ 0 , never ; 1 , seldom ; 2 , sometimes ; 3 , often ; 4 , very often ] ) can be calculated .
we considered a score > 20 to be an indicator of posttraumatic stress disorder to enable comparison with previous studies ( 10,11 ) .
of 131 contacts , 72 ( 55% , 48 unprotected and 24 protected ) filled out the questionnaire .
the median age was 39 years ( range 977 years ) ; 53% were female , and 51% had at least a college education .
protected contacts were younger ( median of 31 vs. 48 years ) and had a higher education ( 88% vs. 31% ) than unprotected contacts .
the mean ies - r score of all contacts was 7.9 ( 95% ci 5.510.3 ) ; the score was > 20 for 16 ( 22% ) contacts .
unprotected contacts had a significantly higher mean ies - r score ( 10.4 95% ci 7.213.6 versus 2.9 , 95% ci 0.65.3 ) ; this result was also seen on the different subscale domains ( table 2 ) . *
we monitored 131 contacts of 2 case - patients with imported mers - cov infections in the netherlands .
laboratory testing did not indicate transmission of the virus , including among contacts with high - risk exposures or those who developed respiratory symptoms .
our findings agree with reports from greece and italy , in which no and limited secondary transmission , respectively , was found among close contacts of mers - cov patients ( 12,13 ) .
survey results show a substantial psychological effect of monitoring on contacts , especially unprotected contacts . as with other emerging infections , such as
marburg hemorrhagic fever and severe acute respiratory syndrome , quarantine or monitoring of contacts leads to psychological distress , measured by high ies - r scores ( 10,11,14 ) .
when stratifying by type of contact , the total mean ies - r score and the subscale scores were highest for unprotected contacts  those with the highest risk for exposure .
we found increased symptoms of posttraumatic stress disorder in a considerable number of contacts , similar to findings by hawryluck et al .
the survey response rate of 55% limits interpretation of results ; motives for noncompliance remain unknown .
, monitoring has contributed to the psychological effect . whether the number of questions induced stress is not known , but participants did not mention this as a concern .
our findings illustrate the feasibility of comprehensive follow - up of contacts of mers - cov patients and clarify the risk for asymptomatic secondary transmission .
the psychological effect of contact monitoring and the observed low rates of mers - cov transmission in several studies , including this investigation , indicate that thoughtful but limited assessment of close contacts is prudent .
identification of close contacts of those who are infected should be carefully considered , and decisions about monitoring and testing of contacts should be made primarily on the basis of clinical and epidemiologic risk factors .
technical appendix . laboratory methods used regarding middle east respiratory syndrome coronavirus and the results of the questionnaire study undertaken to assess contacts knowledge , quality of information , perceptions of severity and vulnerability , and interference of contact monitoring measures with daily life , the netherlands .
notification of 2 imported cases of infection with middle east respiratory syndrome coronavirus in the netherlands triggered comprehensive monitoring of contacts . 
 observed low rates of virus transmission and the psychological effect of contact monitoring indicate that thoughtful assessment of close contacts is prudent and must be guided by clinical and epidemiologic risk factors .