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Paper text:
peritoneal dialysis ( pd ) as an alternative to hemodialysis ( hd ) is variably used for renal replacement therapy in patients with stage 5 chronic kidney disease who wait for or can not receive a renal transplant . the relatively high technique failure rate , mainly due to pd catheter malfunction , is an important reason for pd lagging behind hd .
there are several variations of the pd catheter configuration that may be associated with mechanical and infectious complications and influence peritoneal access longevity .
the most usual variations concern the intra - peritoneal segment ( straight or coiled with and without discs ) , the subcutaneous / extra - peritoneal part ( straight or swan - neck [ sn ] ) , and the number of cuffs ( single or double ) .
the benefit of one catheter over the other has not been conclusively demonstrated by comparative studies designed to evaluate the impact of different catheter configuration on technique complications .
in addition , most of the studies are underpowered by relatively short follow - up .
current clinical practice guidelines for peritoneal access do not clearly indicate the superiority of any particular design over the conventional straight tenckhoff catheter .
the aim of the present study was to evaluate retrospectively the impact of two extra - peritoneal catheter configurations , the straight and sn catheters , on technique , catheter and patient survival .
we performed a retrospective analysis of all pd catheters that were inserted in our center between november 1993 and february 2013 .
our study population comprised 85 consecutive patients , of which 58 were males and 27 were females with at least 3 months of follow - up , starting pd during the study period .
median age at pd initiation was 65 years ( range : 2191 ) and mean time of follow - up was 43.4  31.3 months .
twenty - six patients were diabetics , 52 patients were treated with automated pd ( apd ) , and 33 with continuous ambulatory pd ( capd ) .
two different types of pd catheters were used throughout the study period : double - cuff straight tenckhoff catheter ( quinton instrument company , seattle , wa , usa ) and double - cuff sn catheter ( quinton instrument company , bothell , wa , usa ) .
the insertion of all catheters was performed by the same surgeon using laparoscopic surgical technique .
patients were followed until death , renal transplantation , and transfer to other dialysis modality or another renal center .
survival curves ( patient , technique , and catheter ) were generated according to kaplan  meier method .
technique failure was defined as any situation where a patient on pd was transferred to hd for more than 3 months , excluding those patients that died , were successfully transplanted or recovered residual renal function .
catheter failure was defined as removal of a dysfunctional pd catheter due to catheter - related complications .
straight catheters were used in 38 patients ( straight group ) and sn catheters in 47 patients ( sn group ) .
straight catheters were mostly used in the first 6-year period while sn catheters in the last 6-year period .
a second catheter was placed due to mechanical or infectious reasons in similar numbers in both groups .
technique survival was significantly better in sn versus straight ( log - rank test , p = 0.01 ) while patient and catheter survival were similar ( p = 0.64 and p = 0.52 , respectively ) .
catheter failure was noted in 11 patients , six of straight group and five of sn group due to mechanical ( six patients ) or infectious ( five patients ) complications .
kaplan - meier curves for technique , patient , and catheter survival in both groups are shown in figures 13 , respectively .
technique survival in straight versus swan - neck catheters patient survival in straight versus swan - neck catheters catheter survival in straight versus swan - neck catheters
a better technique survival was found in our group of patients with sn catheters compared to conventional straight ones .
patient and catheter survival rates were similar for both groups of different extra - peritoneal catheter design .
the potential influence of pd catheters extra - peritoneal configuration on long - term outcomes has not been adequately clarified so far . in a recent meta - analysis ,
1-year and 2-year catheter survival between straight and sn pd catheters has been described in only four studies , two of which have been published before 2000 , and no significant difference has been shown .
similar results regarding shapes of the subcutaneous segment have been described in a previous meta - analysis as well .
however , the results of such meta - analyses should be interpreted with caution , mainly due to significant variations in methodologies and follow - up of the included studies .
indeed , local practices , and the length of follow - up are particularly important in comparing pd access outcomes . the only demographic difference between the two groups of our study was significantly higher frequency of apd use in sn catheters group .
this may be a potential confounding factor in the better technique survival noted in sn catheters group .
unfortunately , in the above - mentioned meta - analyses , data on pd submodality are lacking .
changes in pd solutions composition over the last few years and , in general , the improvements of overall practices in pd could also contribute to better technique survival observed in sn catheters group as these catheters have been increasingly used over the last decade in our unit .
this is consistent with the observation made by many investigators that the more recent studies displayed better catheter survival rates compared with the older ones .
however , this finding should be interpreted with caution due to the retrospective design of the study and the potential influence of many factors that our study was not appropriately designed to evaluate .
the similar catheter survival rate demonstrated for both groups appears to be the only conclusive result .
nevertheless , the type of peritoneal catheter is an important aspect regarding the outcome of pd . in the existing literature ,
there is no consensus about the type of catheter that is to be preferred for successful pd .
however , it is generally accepted that pd catheter selection should be based on the individual patient 's requirements as well as on local practices and experience .
our study , despite the abovementioned limitations , evaluated the long - term effect of two different extra - peritoneal catheter designs on patient and technique survival and provides the rationale for large randomized trials to definitely address the important issue of the optimal pd catheter .
peritoneal dialysis ( pd ) is limited mainly by a higher technique failure rate as compared to hemodialysis ( hd ) , catheter malfunction being an important reason . 
 intra- and extra - peritoneal catheter configuration may be associated with mechanical and infectious complications affecting method survival . 
 we report our experience with two extra - peritoneal catheter configurations : the straight and the swan - neck ( sn ) catheters . 
 a total of 85 consecutive patients , 58 males and 27 females were included in the study . among them , 
 26 were diabetics ; 52 were treated with automated pd ( apd ) and 33 with continuous ambulatory pd ( capd ) . 
 straight catheters were used in 38 patients ( straight group ) and sn catheters in 47 patients ( sn group ) . 
 straight catheters were mostly used in the first 6-year period while sn catheters in the last 6-year period . 
 the baseline demographics were similar between the two groups . a significantly higher frequency of apd use was observed in sn group . 
 technique survival was better with sn versus straight ( log - rank test , p = 0.01 ) while patient and catheter survival were similar . 
 a better technique survival is noted in our group of patients with sn catheters . 
 an additional factor could be the significantly higher frequency of apd use in this group . 
 changes in pd solutions composition could also contribute to improvement in technique survival . 
 the outcome for patients and catheter types used was similar .