You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["RNA", "CellLine", "Protein", "DNA", "CellType"].

Please return the output as a JSON object of the format: {"DNA" : ["TAL1", ...], "RNA": ["mRNAs", ...], "CellLine": ["T cells", ...], "CellType": ["monocytes", ...], "Protein": ["IL-2", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

The effect of toremifene therapy on serum immunoglobulin levels in breast cancer. Estrogens and anti-estrogens enhance the number of immunoglobulin (Ig) -secreting cells in pokeweed mitogen (PWM) -stimulated lymphocyte cultures. Lymphocytes from patients who have received anti-estrogen therapy show similar enhancement of Ig-secreting cells after PWM stimulation. In this study the effect of anti-estrogen (toremifene) therapy on serum immunoglobulin (IgA, IgM, IgG) levels in breast cancer patients was investigated. Serum Ig levels were followed up to two years after or during the therapy. An unexpected finding was that the Ig levels decreased during the follow-up period. This decrease was seen in patients who responded to the therapy as well as in those who did not.
{"CellLine": ["PWM stimulation", "pokeweed mitogen (PWM) - stimulated lymphocyte cultures"], "CellType": ["immunoglobulin (Ig) - secreting cells", "Ig - secreting cells", "Lymphocytes"], "DNA": [], "Protein": ["IgG", "PWM", "IgA", "IgM", "serum immunoglobulin", "pokeweed mitogen"], "RNA": []}