You will be presented with a collection of medical randomized controlled trial (RCT) reports addressing a shared clinical question -- for instance, the efficacy of a medical intervention on a disease or condition. Given the titles and abstracts of these reports, your task is to generate the conclusion of the systematic review article synthesizing the key findings. Your conclusion should be a few sentences long. In your response, include only the conclusion and no other text. The RCT reports are below.



Title 1:
Preliminary results of spinal cord compression recurrence evaluation (score-1) study comparing short-course versus long-course radiotherapy for local control of malignant epidural spinal cord compression.
Abstract 1:
PURPOSE To compare the results of short-course vs. long-course radiotherapy ( RT ) for metastatic spinal cord compression . METHODS AND MATERIAL S A total of 231 patients who underwent RT between January 2006 and August 2007 were included in this two-arm prospect i ve nonr and omized study . Patients received short-course ( n = 114 ) or long-course ( n = 117 ) RT . The primary endpoint was progression-free survival ( PFS ) . The secondary endpoints were local control ( LC ) , functional outcome , and overall survival ( OS ) . An additional 10 potential prognostic factors were investigated for outcomes . PFS and LC were judged according to motor function , not pain control . RESULTS The PFS rate at 12 months was 72 % after long-course and 55 % after short-course RT ( p = 0.034 ) . These results were confirmed in a multivariate analysis ( relative risk , 1.33 ; 95 % confidence interval , 1.01 - 1.79 ; p = 0.046 ) . The 12-month LC rate was 77 % and 61 % after long-course and short-course RT , respectively ( p = 0.032 ) . These results were also confirmed in a multivariate analysis ( relative risk , 1.49 ; 95 % confidence interval , 1.03 - 2.24 ; p = 0.035 ) . The corresponding 12-month OS rates were 32 % and 25 % ( p = 0.37 ) . Improvement in motor function was observed in 30 % and 28 % of patients undergoing long-course vs. short-course RT , respectively ( p = 0.61 ) . In addition to radiation schedule , PFS was associated with the interval to developing motor deficits before RT ( relative risk , 1.99 ; 95 % confidence interval , 1.10 - 3.55 ; p = 0.024 ) . LC was associated only with the radiation schedule . Post-RT motor function was associated with performance status ( p = 0.031 ) , tumor type ( p = 0.013 ) , interval to developing motor deficits ( p = 0.001 ) , and bisphosphonate administration ( p = 0.006 ) . OS was associated with performance status ( p < 0.001 ) , number of involved vertebrae ( p = 0.007 ) , visceral metastases ( p < 0.001 ) , ambulatory status ( p < 0.001 ) , and bisphosphonate administration ( p < 0.001 ) . CONCLUSION Short-course and long-course RT result ed in similar functional outcome and OS . Long-course RT was significant for improved PFS and improved LC
The review indicated that 10 and 6 Gy may produce superior overall response ( OR ) and complete response ( CR ) rates compared to 8 Gy , and 6 Gy may result in better partial response ( PR ) than 8 Gy .
8 Gy SFRT was the most commonly administered dose for palliation of bone metastases supporting its efficacy and safety .