Given an abstract from a research paper, your task is to identify and label relationships between chemical compounds and genes mentioned in the abstract.

The relationship type must be one of ['DOWNREGULATOR', 'SUBSTRATE', 'INDIRECT-REGULATOR', 'PART-OF', 'MODULATOR-ACTIVATOR', 'REGULATOR', 'INHIBITOR', 'COFACTOR', 'UPREGULATOR', 'ACTIVATOR', 'ANTAGONIST', 'NOT', 'INDIRECT-DOWNREGULATOR', 'SUBSTRATE_PRODUCT-OF', 'INDIRECT-UPREGULATOR', 'AGONIST', 'PRODUCT-OF', 'MODULATOR', 'DIRECT-REGULATOR', 'UNDEFINED', 'AGONIST-INHIBITOR', 'AGONIST-ACTIVATOR', 'MODULATOR-INHIBITOR'].

Please format your output as a JSON array. Each entry in the array should express a single relation, formatted as ["<Entity_A>", "<RELATION_A_B>", "<Entity_B>"]. If no relations can be found, please output an empty JSON array [].

Abstract:

The primary structure of porcine aminoacylase 1 deduced from cDNA sequence. A cDNA encoding the complete amino acid sequence of aminoacylase 1 (N-acylamino acid aminohydrolase, ACY-1) [ EC 3.5.1.14 ], a dimeric metalloprotein having two Zn2 + in the molecule, which catalyzes the deacylation of N-acylated L-amino acids except L-aspartic acid, has been isolated from porcine kidney lambda gt10 cDNA library and sequenced. From sequence analysis of the cDNA and the N- and C-terminal amino acid analyses of the purified protein, it is deduced that porcine kidney ACY-1 consists of two identical subunits (M (r) 45,260), each of which consists of a single chain of 406 amino acids with acetylalanine at the N-terminus. A cDNA encoding porcine liver ACY-1 was also cloned. The amino acid sequence deduced from the nucleotide sequence of the cDNA from porcine liver was identical to that deduced for porcine kidney ACY-1. Northern blot analysis suggested that ACY-1 is more highly expressed in kidney than in liver. Comparison of the amino acid sequence of porcine ACY-1 with those of other Zn2 + -binding metalloenzymes showed no significant homologies in either the overall sequence or the consensus sequences for the metal binding sites. This indicates that ACY-1 is a new type of metalloprotein.
[["N-acylated L-amino acids", "SUBSTRATE", "N-acylamino acid aminohydrolase"], ["amino acid", "PART-OF", "ACY-1"], ["N-acylated L-amino acids", "SUBSTRATE", "ACY-1"], ["amino acid", "PART-OF", "porcine kidney ACY-1"], ["L-aspartic acid", "NOT", "metalloprotein"], ["amino acid", "PART-OF", "EC 3.5.1.14"], ["N-acylated L-amino acids", "SUBSTRATE", "aminoacylase 1"], ["nucleotide", "PART-OF", "porcine kidney ACY-1"], ["amino acid", "PART-OF", "Zn2 + -binding metalloenzymes"], ["L-aspartic acid", "NOT", "ACY-1"], ["amino acids", "PART-OF", "porcine kidney ACY-1"], ["acetylalanine", "PART-OF", "porcine kidney ACY-1"], ["N-acylated L-amino acids", "SUBSTRATE", "EC 3.5.1.14"], ["N-acylated L-amino acids", "SUBSTRATE", "metalloprotein"], ["amino acid", "PART-OF", "aminoacylase 1"], ["L-aspartic acid", "NOT", "EC 3.5.1.14"], ["L-aspartic acid", "NOT", "N-acylamino acid aminohydrolase"], ["L-aspartic acid", "NOT", "aminoacylase 1"], ["amino acid", "PART-OF", "N-acylamino acid aminohydrolase"], ["amino acid", "PART-OF", "porcine ACY-1"]]