You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["RNA", "CellLine", "Protein", "DNA", "CellType"].

Please return the output as a JSON object of the format: {"DNA" : ["TAL1", ...], "RNA": ["mRNAs", ...], "CellLine": ["T cells", ...], "CellType": ["monocytes", ...], "Protein": ["IL-2", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

[ Regulatory effect of insulin on glucocorticoid receptor in human peripheral leukocytes ] The regulatory effect of insulin on the specific binding power of glucocorticoid receptor (GR) of human leukocytes was assessed by the unoccupied receptor sites capable of combining with [3H] labelled dexamethasone measured at 3 and 24 h after incubation with various concentrations of insulin added to the medium. After 3 h incubation the specific binding power with [3H] Dex was decreased by 23. 3 + /-10. 0, 32. 2 + /-13. 2 and 54. 3 + /-9. 2% (P greater than 0. 05, P greater than 0. 05 and P less than 0. 01 as compared with the control value of 100 in the absence of insulin) respectively in the presence of 20 mU / L (physiological testing concentration), 200 mU / L (physiological upper limit) and 2, 000 mU / L (pharmacological concentration) insulin in the incubation medium. After 24 h incubation the decrease of these values increased respectively to 43. 5 + /-19. 0, 56. 1 + /-20. 7 and 80. 2 + /-15. 5 (P less than 0. 05, P less than 0. 01 and P less than 0. 01 compared with control). Thus the inhibitory effect of insulin on the GR binding power is both dose-and time-dependent, which strongly suggests that GR is tonically controlled by insulin concentration change under physiological conditions.
{"CellLine": [], "CellType": ["human peripheral leukocytes", "human leukocytes"], "DNA": [], "Protein": ["glucocorticoid receptor", "GR", "insulin", "glucocorticoid receptor (GR)", "unoccupied receptor sites"], "RNA": []}