You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["Protein", "Chemical"].

Please return the output as a JSON object of the format: {"Chemical" : ["Dexamethasone", ...], "Protein" : ["BRCA-1", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Gemcitabine and Pemetrexed disodium in treating breast cancer.
Pemetrexed disodium (Alimta, LY231514) is a novel, multitargeted antifolate that inhibits thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyl transferase. This agent is broadly active in a wide variety of solid tumors, including breast cancer. Pemetrexed disodium has also shown clinically relevant activity in combination with gemcitabine (Gemzar). This combination is being evaluated for the treatment of metastatic breast cancer.
{"Chemical": ["gemcitabine", "thymidylate", "Alimta", "Pemetrexed disodium", "dihydrofolate", "glycinamide ribonucleotide formyl", "LY231514", "Gemzar", "Gemcitabine"], "Protein": ["dihydrofolate reductase", "thymidylate synthase", "glycinamide ribonucleotide formyl transferase"]}