You are presented with a paragraph from a COVID-19 literature. Classify the topics of this piece of text by choosing from the following categories:

- Epidemic Forecasting: The content relates to predictions about the spread of COVID-19.
- Treatment: The paragraph discusses therapeutic methods or medication for COVID-19.
- Prevention: The content covers measures to prevent the spread of COVID-19.
- Mechanism: The paragraph explains the biological mechanisms of the virus.
- Case Report: The content is a report of a COVID-19 case.
- Transmission: The paragraph discusses how COVID-19 is transmitted.
- Diagnosis: The content is about diagnosing COVID-19 in individuals.

Your classification should be provided as an element within a JSON array. The array should be formatted with topics enclosed in double quotes and separated by commas, following the JSON format, for example: ["Topic1", "Topic2", ...]. Include all applicable topics within the array. Your output should be a valid JSON array, and no additional text should be included in your response.

Article:

The coronavirus pandemic is caused by the SARS-CoV-2. Vaccination appears to offer the way out of this pandemic. Vaccines against this virus make use of the SARS-CoV-2's spike protein, an essential protein on the surface of the virus that it uses to attach itself to the host cells. In viral vector vaccines (AstraZeneca, Sputnik, Johnson & Johnson) the gene for the spike protein is introduced into an adenovirus. Following vaccination, the modified adenovirus will infect cells of the host, which will subsequently start to produce the spike protein, causing an immune response. RNA vaccines (Pfizer, Moderna) only introduce messenger RNA for the spike protein into host cells, which the messenger RNA uses to produce spike protein. Viral vector vaccines and RNA vaccines are not only faster to develop and safer to produce than traditional vaccines, they are also easier to modify to new viruses and virus variants. The latter may be of great importance for future pandemics.
["Mechanism", "Treatment"]