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Paper text:

 aeadverse eventciconfidence intervalsdtpa - ipvdiphtheria - tetanus - acellular pertussis - inactivated polio vaccinedtwpdiphtheria ; tetanus and whole cell pertussis vaccineepiexpanded program on immunizationhibhaemophilus influenza type blflimits of flocculationsaeserious adverse eventsdstandard deviationwhoworld health organization diphtheria - tetanus - acellular pertussis - inactivated polio vaccine diphtheria ; tetanus and whole cell pertussis vaccine expanded program on immunization haemophilus influenza type b limits of flocculation serious adverse event world health organization
hhh , sk , nk and ovdm are employees of gsk group of companies and hhh and ovdm declare having gsk stocks .
da and t - wy were employees of the gsk group of companies at the time of the study .
the authors acknowledge : karin hardt ( employee of the glaxosmithkline group of companies ) for her role in developing the protocol ; murtaza shipchandler , chua tran thuy and greg bewick ( all employees of the glaxosmithkline group of companies ) , and supriya chauhan and janice tan ( quintiles on behalf of gsk vaccines ) for study coordination and project management ; prachee panda for providing writing support and jesse quigley - jones for editorial support and coordination of this publication ( both employees of the glaxosmithkline group of companies ) .
glaxosmithkline biologicals sa sponsored and funded the study conduct , analyses of data and the development and publication of the manuscript .
abstractthe introduction of combination vaccines plays a significant role in increasing vaccine acceptance and widening vaccine coverage . 
 primary vaccination against diphtheria , tetanus , pertussis , poliomyelitis and haemophilus influenza type b ( hib ) diseases has been implemented in vietnam . in this study 
 we evaluated the safety and reactogenicity of combined diphtheria - tetanus - pertussis - inactivated polio ( dtpa - ipv)/hib vaccine when administered as a booster dose in 300 healthy vietnamese children < 2  years of age ( mean age : 15.8 months ) . during the 4-day follow - up period , pain ( 31.7% ) and redness ( 27.3% ) 
 were the most frequent solicited local symptoms . 
 pain ( 2% ) was also the most frequent grade 3 local symptom . 
 one subject reported 2 serious adverse events that were not causally related to the study vaccine . 
 dtpa - ipv / hib conjugate vaccine was well tolerated as a booster dose in healthy vietnamese children aged < 2  years .