You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["RNA", "CellLine", "Protein", "DNA", "CellType"].

Please return the output as a JSON object of the format: {"DNA" : ["TAL1", ...], "RNA": ["mRNAs", ...], "CellLine": ["T cells", ...], "CellType": ["monocytes", ...], "Protein": ["IL-2", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Surrogate thyroglobulin receptors and T cell proliferation in Hashimoto 's thyroiditis. Immunoglobulin molecules on the surface of a B lymphocyte are the endogenous " receptors " to which specific antigens bind. Studies in mice have shown that a monoclonal antibody, conjugated with palmitate to provide a lipid tail, can be inserted into the cell membrane to provide a " surrogate " antigen receptor. We have investigated whether a palmitate conjugate of a human monoclonal antibody specific for thyroglobulin (TG) could function as a surrogate TG receptor on blood mononuclear cells separated into fractions enriched for T cells or depleted of T cells (non-T cells). Using flow cytometry, we detected surrogate TG receptors on non-T (but not on T) cells from 11 of 11 individuals studied (5 Hashimoto patients and 6 control donors). In contrast, endogenous TG receptors could only be detected on non-T cells from 1 of 3 Hashimoto patients and from 0 of 4 control donors. Because of the efficient binding of TG by surrogate receptors on non-T cells, we assessed the ability of such cells to present TG to T cells. Proliferation in response to TG was observed in T cells from only 1 of 5 Hashimoto patients. This low frequency of response was no different from that previously detected using cultures of T cells and autologous dendritic cells. Therefore, the successful generation of surrogate receptors on non-T cells is not associated with more efficient TG presentation of T cells. Furthermore, the significance of the present study is that the T cells, not the antigen-presenting cells, are likely to be the limiting element in the T cell proliferative response to TG and other thyroid autoantigens.
{"CellLine": [], "CellType": ["antigen - presenting cells", "autologous dendritic cells", "blood mononuclear cells", "non - T cells", "B lymphocyte", "the T cells", "non - T (but not on T) cells", "such cells", "T cell", "T cells"], "DNA": [], "Protein": ["palmitate conjugate", "surrogate receptors", "surrogate TG receptor", "Immunoglobulin molecules", "thyroglobulin (TG)", "thyroid autoantigens", "endogenous TG receptors", "thyroglobulin receptors", "monoclonal antibody", "human monoclonal antibody", "surrogate \" antigen receptor", "thyroglobulin", "surrogate TG receptors", "TG"], "RNA": []}