You will be shown the abstract of a medical clinical trial report. Your task is to extract all the findings from this report into a JSON array. Each finding should contain the following five elements:

- Intervention: The medical intervention being tested. This should be a text span copied from the input passage.
- Comparator: The baseline against which the intervention is being evaluated. This should be a text span copied from the input passage. If no comparator is reported, set to `null`.
- Outcome: The medical outcome whose effect is being measured. This should be a text span copied from the input passage.
- Effect: The effect of the intervention on the outcome, relative to the comparator. The effect should be one of the following three values: ("significantly increased", "significantly decreased", "no significant difference").
- Evidence: The evidence for the effect. This should be a text span copied from the input passage.

Please format your output as a JSON array. Each entry in the output should be an array containing the 5 elements listed above, in the following order: [<intervention>, <comparator>, <outcome>, <effect>, <evidence>].

For example, an output with two findings might read:
```
[["aspirin", "placebo", "headache severity", "significantly decreased", "Mean headache severity was significantly decreased in the aspirin group compared to the placebo group (p < 0.05)."], ["aspirin", "placebo", "weight loss", "no significant difference", "We did not observe any difference in weight loss between the group given aspirin relative to the control group"]]
```

There are 4 finding(s) in the abstract below. Please extract them. Output only the JSON array with these 4 findings. Do not include any additional text.

Abstract:
ABSTRACT.STUDY OBJECTIVES: The aim of this study was to evaluate the efficacy and tolerability of novel combination naproxen sodium (NS) and diphenhydramine (DPH) in subjects with postoperative dental pain along with transient insomnia induced by 5 h sleep phase advance. The present studies aimed to demonstrate the added benefit and optimal dosages of the combination product over individual ingredients alone in improving sleep and pain.

ABSTRACT.METHODS: Each of the two studies was a two-centre, randomised, double-blind and double-dummy trial. In the first study, subjects were randomised into one of the following treatment arms: NS 440 mg/DPH 50 mg, NS 220 mg/DPH 50 mg, NS 440 mg or DPH 50 mg. In the second study, subjects received either NS 440 mg/DPH 25 mg, NS 440 mg or DPH 50 mg. The co-primary end-points in both studies were wake time after sleep onset (WASO) and sleep latency (SL) measured by actigraphy. Other secondary sleep and pain end-points were also assessed.

ABSTRACT.RESULTS: The intent-to-treat population included 712 and 267 subjects from studies one and two, respectively. In the first study, only the NS 440 mg/DPH 50 mg combination showed significant improvements in both WASO vs. NS alone (−70.3 min p = 0.0002) and SL vs. DPH alone (25.50 and 41.50 min respectively, p < 0.0001). In the second study, the NS 440 mg/DPH 25 mg combination failed to show any significant improvements vs. either component alone.

ABSTRACT.CONCLUSIONS: Only the NS 440 mg/DPH 50 mg combination demonstrated improvement in both sleep latency vs. DPH 50 mg and sleep maintenance (WASO) vs. NS 440 mg. There were no serious or unexpected adverse events reported in either study. Clinical Trial Registration: NCT01280591 (study 1); NCT01495858 (study 2)

Findings:
[["Naproxen sodium + diphenhydramine (440mg/25mg)", "Naproxen sodium", "Wake time after sleep onset improvement ", "no significant difference", "the NS 440 mg/DPH 25 mg combination failed to show any significant improvements vs. either component alone."], ["Naproxen sodium + diphenhydramine (440mg/25mg)", "Diphenhydramine ", "Wake time after sleep onset improvement ", "no significant difference", "NS 440 mg/DPH 25 mg combination failed to show any significant improvements vs. either component alone."], ["Naproxen sodium + diphenhydramine (440 mg/50 mg)", "Naproxen sodium", "Wake time after sleep onset improvement ", "significantly increased", "In the first study, only the NS 440 mg/DPH 50 mg combination showed significant improvements in both WASO vs. NS alone (\u221270.3 min p = 0.0002) and SL vs. DPH alone (25.50 and 41.50 min respectively, p \u003c 0.0001)."], ["Naproxen sodium + diphenhydramine (440mg/50mg)", "Diphenhydramine", "Sleep latency improvement ", "significantly increased", "In the first study, only the NS 440 mg/DPH 50 mg combination showed significant improvements in both WASO vs. NS alone (\u221270.3 min p = 0.0002) and SL vs. DPH alone (25.50 and 41.50 min respectively, p \u003c 0.0001)."]]