You will be shown an abstract from a biomedical research paper. Given this abstract, your task is to extract all unique entities of the following types: ["RNA", "CellLine", "Protein", "DNA", "CellType"].

Please return the output as a JSON object of the format: {"DNA" : ["TAL1", ...], "RNA": ["mRNAs", ...], "CellLine": ["T cells", ...], "CellType": ["monocytes", ...], "Protein": ["IL-2", ...]}. The keys should be entity types and values should be lists of extracted entities belonging to the corresponding type. If you cannot find entities belonging to a specific type, the value should be [].

Only output the JSON object and do not include any additional text.

Abstract:

Nuclear transcription factors that bind to elements of the IL-2 promoter. Induction requirements in primary human T cells. Prior studies have identified several elements that contribute to the activity of the IL-2 promoter in the stimulated T cell line, Jurkat. The sites and their corresponding nuclear binding factors include: NF-kappa B, AP-1, AP-3, OCT-1, and NF-AT. The latter " nuclear factor for activated T cells " likely contributes to the tissue specificity of IL-2 gene expression. Using electrophoretic mobility shift assays, we have studied these transcription factors in primary T cells from human blood to verify their presence in a physiologic setting and to identify the signals that stimulate factor activity. All factors are induced in the nuclei of T cells upon activation with mitogens but not with exogenous IL-2 growth factor. However, the signaling requirements and sensitivity to protein synthesis inhibitors differ considerably. Only the activities for NF-AT and AP-1 sites require two signals for optimal induction, i. e., PMA plus either lectin or antibody to the CD3 or CD28 surface molecules. Other factors are induced by lectin, antibody, and / or PMA alone. After appropriate stimulation, both NF-AT and AP-1 are peculiarly sensitive to the protein synthesis inhibitor anisomycin. Our data correlate the activity of NF-AT and AP-1 in gel shift assays with the two signals requirements for IL-2 gene expression.
{"CellLine": ["T cell line", "Jurkat", "activated T cells"], "CellType": ["primary T cells", "primary human T cells", "T cells"], "DNA": ["The latter", "IL - 2 promoter", "NF - AT and AP - 1 sites", "IL - 2 gene"], "Protein": ["NF - AT", "mitogens", "OCT - 1", "AP - 3", "CD28 surface molecules", "transcription factors", "antibody", "nuclear factor for activated T cells", "Nuclear transcription factors", "AP - 1", "CD3", "NF - kappa B", "IL - 2", "lectin", "exogenous IL - 2 growth factor"], "RNA": []}