Intravoxel Incoherent Motion Prognostic Value in the Initial Evaluation of Patients With Acute Ischemic Strokes Using 3 Tesla Magnetic Resonance Imaging
Intravoxel Incoherent Motion Prognostic Value in the Initial Evaluation of Patients With Acute Ischemic Strokes Using 3 Tesla Magnetic Resonance Imaging
Ischemic strokes are the first cause of handicap in adult people, the second cause of
 dementia and the third cause of death in France. Brain Magnetic Resonance (MR) initial
 assessment is mandatory to get the right diagnosis, to exclude hemorrhagic lesions and to
 determine the best treatment.

 The conventional diffusion weighted imaging sequence is used to establish the diagnosis and
 to estimate the volume of ischemic lesions. The perfusion weighted imaging sequences are also
 used to assess the diffusion-perfusion mismatch which is supposed to be the ischemic penumbra
 corresponding to territories that could be saved with appropriate treatments.

 IntraVoxel Incoherent Motion (IVIM) is a multi-b diffusion sequence which allows to extract
 four quantitative variables (D, D*, f, ADC) related to the true molecular diffusion and
 correlated to the microvascular perfusion.

 It's a quick sequence with no need of contrast injection and allowing a perfect
 coregistration with the true diffusion. It has been validated in many pathologies but not in
 acute strokes.

 The feasibility of this sequence in acute ischemic strokes has already been assessed with
 interesting results.

 The study aims to assess the correlation between the quantitative values of IVIM at initial
 MR exam and the modified Rankin Scale (mRS) score 3 months after an acute ischemic stroke.
Inclusion Criteria:

 -  Adult patients

 -  Admitted for an acute ischemic stroke

 -  Affiliated to a Social Security scheme

 Exclusion Criteria:

 -  Absolute contraindications to MRI

 -  Pregnant or breastfeeding woman