Bronchial Hyperreactivity in Atopic Dermatitis Patients - a 10 Year Follow-up
Bronchial Hyperreactivity in Atopic Dermatitis Patients - a 10 Year Follow-up
The investigators will contact 64 patients with atopic dermatitis (AD) who participated in a
 long-term tacrolimus ointment trial in Helsinki 10 years ago, and ask them to participate in
 this follow-up study. The investigators will do the same tests as 10 years ago, i.e.
 bronchial hyperreactivity, skin prick tests, serum-IgE, Mantoux-test (2 TU), and
 questionnaires about asthma and allergic rhinitis symptoms. The investigators also collect
 data about their AD medication during the last 10 years.

 The investigators hypothesis is that when the skin condition improves in patients with AD the
 brochial hyperreactivity improves. The investigators also want to study whether different
 treatments play a role in the development or resolution of bronchial hyperreactivity.
We will by letters and telephone contact all patients (n=64) who fulfill the inclusion
 criteria for this study.

 The testing in the study (bronchial hyperreactivity, skin prick testing, serum IgE) is
 cross-sectional, but we retrospectively collect data from the last 10 years about the skin
 condition and medication for atopic diseases.
Inclusion Criteria:

 -  Patient has participated in the FG-506-06-21 study in Helsinki

 -  Patient was tested for bronchial hyperreactivity in the years 1998-2000

 -  Patient gives signed informed consent to participate in this study