Comparison of Two Types of Biopsy in Suspicious Axillary Lymph Nodes
Comparison of Two Types of Biopsy in Suspicious Axillary Lymph Nodes
Axillary lymph node status is a vital prognostic factor in breast cancer patients and
 provides crucial information for making treatment decisions. Ultrasound test with subsequent
 fine needle aspiration (FNA) biopsy in nodes with suspicious features remains the standard of
 axillary lymph node workup. Insufficient sampling and limited diagnostic accuracy of
 cytological test compromise the outcome the preoperative lymph node staging strategy
 especially in patients with intermediate suspicious nodes. This prospective study is to
 compare the performance of a crpo-assisted core biopsy with FNA.
This prospective study was planned to evaluate the superiority of a core needle biopsy device
 with a special cryo-assisted rotational design (Cassi II, USA) compared with FNA for biopsy
 of intermediately suspicious lymph nodes. Eligible patients would be randomized to one of two
 arms by 1:2 : Core with FNA or FNA alone. The diagnostic accuracy and adverse outcome of core
 and FNA would be compared.
Inclusion Criteria:

 -  Histologically confirmed invasive breast cancer.

 -  With axillary lymph node with thickened cortex.

 -  Planned for sentinel lymph node biopsy or axillary clearance.

 Exclusion Criteria:

 -  Nodes ultrasonographically normal.

 -  Nodes with hilar displacement .

 -  Palpable matted nodes.