Neurological Effects of Chemotherapy and Radiation Therapy in Patients With Colon Cancer
Neurological Effects of Chemotherapy and Radiation Therapy in Patients With Colon Cancer
RATIONALE: Learning about the long-term effects of chemotherapy and radiation therapy on
 brain function may help doctors plan cancer treatments.

 PURPOSE: This clinical trial is looking at the neurological effects of chemotherapy and
 radiation therapy in patients with colon cancer.
OBJECTIVES:

 Primary

 -  Identify the nature and long-term ramifications of CNS injury as a result of cancer
 treatment in patients with colon cancer.

 Secondary

 -  Analyze differences in cognitive measures and MRI data in these patients.

 -  Correlate MRI measures with cognitive performance in these patients.

 OUTLINE: Patients undergo cognitive performance assessment and MRI.

 PROJECTED ACCRUAL: A total of 42 patients will be accrued for this study.
DISEASE CHARACTERISTICS:

 -  Diagnosis of colon cancer

 -  Received chemotherapy and radiotherapy for colon cancer

 PATIENT CHARACTERISTICS:

 -  Not specified

 PRIOR CONCURRENT THERAPY:

 -  See Disease Characteristics