Citalopram for Sx/Util in Acute Coronary Syndrome Patients
Citalopram for Sx/Util in Acute Coronary Syndrome Patients
Symptoms (chest pain, shortness of breath, dizziness, etc.) and treatment usage (doctor or
 emergency room visits, testing, hospital days, etc.) in patients with Acute Coronary
 Syndromes are known to be related to emotional distress (Anxiety, Depression and Anger). In
 addition, behavioral treatment of emotional distress is known to decrease symptoms, and
 treatment usage. The present protocol tests whether the addition of a medication known to
 reduce emotional distress can also reduce symptoms and treatment usage.

 This will done by recruiting patients with ACS during their hospital stay, randomizing them
 to receive citalopram or placebo, and then examining their symptoms and treatment usage at 6
 months.
Not applicable. Study not funded.
Inclusion Criteria:

 -  Admission to hospital for chest pain/dyspnea, typical ECG changes plus positive
 tropinins

 Exclusion Criteria:

 -  age less than 18

 -  cognitive impairment (per MMSE)

 -  geographic unavailability for followup

 -  unwillingness to participate

 -  illiteracy

 -  Hx cardiac transplant

 -  untreated hypothyroidism

 -  hepatic dysfunction

 -  prior adverse reaction to citalopram

 -  history of Bipolar Disorder

 -  untreated Sleep Apnea

 -  chronic steroid therapy

 -  active substance abuse (e.g., within past year)

 -  near term mortal illness

 -  current mental health treatment

 -  signitificant suicide risk