Plasma Levels of GDF-9 and GDF-15 in Patients With Polycystic Ovary Syndrome.
Plasma Levels of GDF-9 and GDF-15 in Patients With Polycystic Ovary Syndrome.
The purpose of this study is to determine the plasma levels of GDF-9 and GDF-15, and their
 association with bone and cardiovascular parameters in patients with Polycystic Ovary
 Syndrome.
Inclusion Criteria:

 -  Female patients at ages 25-35 diagnosed with polycystic ovarian syndrome and
 idiopathic hirsutism

 Exclusion Criteria:

 -  acute infectious disease, a thyroid, pituitary, nutritional, inflammatory, hepatic,
 renal, or neoplastic disorder; history of cardiovascular disease or pulmonary
 embolism; a family history of coronary artery disease; smoking history; hypertension;
 diabetes mellitus; use of oral contraceptives, anti-androgens and drugs known to
 interfere with cytokine release, such as corticosteroids, immunosuppressors, or
 nonsteroidal antiinflammatory drugs.

 any medication known to affect hormonal or metabolic parameters.