HPV Integration and Tumorigenesis of Uterine Cervical Adenocarcinoma
HPV Integration and Tumorigenesis of Uterine Cervical Adenocarcinoma
This study aims to analyze the multi-omics results between uterine cervical adenocarcinoma
 patients with and without human papillomavirus (HPV) infections. The multi-omics profiles
 include genome wide association study (GWAS), whole exome sequencing, analysis of
 transcriptomics and metabolomics. The HPV integration status is interpreted by GWAS. A
 comprehensive multi-omics will reveal the role of HPV integration in the molecular mechanism
 of tumorigenesis and prognosis of uterine cervical adenocarcinoma.
Inclusion Criteria:

 -  Confirmed primary adenocarcinoma of the uterine cervix

 -  Signed an approved informed consents

 -  Feasible for biopsy

 Exclusion Criteria:

 -  Not meeting all of the inclusion criteria