Thyroxin in Subclinical Hypothyroidism
Thyroxin in Subclinical Hypothyroidism
Subclinical hypothyroidism(SCH) is the elevated thyroid stimulating hormone (TSH) with normal
 free Thyroxine levels and it is a mild or compensated form of primary hypothyroidism. It has
 been suggested that SCH is more prevalent in infertile women (especially in women with
 ovulatory disorders.Various rates of SCH was reported in infertile women in different
 populations
Despite well-established recommendations on screening and treatment of overt hypothyroid in
 infertile women, there is a controversy regard the treatment of SCH in infertile women .

 There are few published data on the prevalence of SCH and the outcome of treatment of SCH in
 infertile women, many were conducted during IVF cycles . Moreover there are inconsistent
 results in these studies being authors advised to treat SCH before IVF and some other
 articles find out no any benefit regarding treatment with Thyroxine in SCH
Inclusion Criteria:

 1. Unexplained infertility

 2. TSH more than 2.5 and normal T3,T4 levels

 3. Negative for Anti-thyroid antibodies

 Exclusion Criteria:

 1. current history of overt hypo or hyperthyroidism

 2. recurrent pregnancy loss

 3. women having franked causes for infertility like tubal blockage, pelvic inflammatory
 disease, endometriosis , ,uterine factor

 4. Ovarian dysfunction or decreased ovarian reserve

 5. abnormal seminal fluid analysis or male factor