A Registered Cohort Study on Wilson's Disease
A Registered Cohort Study on Wilson's Disease
The aim of this study is to determine the clinical spectrum and natural progression of
 Wilson's Disease in a prospective multicenter natural history study, to assess the clinical,
 genetic, epigenetic features and biomarkers of patients with Wilson's Disease to optimize
 clinical management.
Inclusion Criteria:

 -  Patients with the genetic diagnosis of Wilson's Disease

 -  Asymptomatic Wilson's Disease carriers

 -  Relatives of Wilson's Disease patients or carriers

 -  Unrelated healthy controls

 -  Participants or Parent(s)/legal guardian(s) willing and able to complete the informed
 consent process

 Exclusion Criteria:

 * Participants are unable to comply with study procedures and visit schedule