Usage of Multiple Drugs in Treatment of Postoperative Vomiting After Laparoscopic Appendectomy
Usage of Multiple Drugs in Treatment of Postoperative Vomiting After Laparoscopic Appendectomy
To compare and evaluate the antiemetic effect and the safety of ondansetron, inhalational
 isopropyl alcohol and super hydration on adult patients after laparoscopic appendectomy.
This prospective double-blind study done on 240 patients admitted to surgical I.C.U after
 laparoscopic appendectomy. Those who had preoperative Koivuranta vomiting score of more than
 3 enrolled in our study. Every group contains 80 patients. Patients of group A received
 ondansetron 4 mg intravenous immediately once reached to I.C.U and another same dose after 6
 hours while patients of group B received isopropyl alcohol 70% inhalation every 15 min for 4
 times then repeated after 6 hours. The last group C received intravenous normal saline at
 rate of 20 ml/kg over 30 minute and repeated by the same dose after 6 hours. The duration of
 the study was 24 hours post-operatively. As PONV is self-limited within 24 hours.
Inclusion Criteria:

 postoperative nausea and vomiting

 Exclusion Criteria:

 systemic disease as diabetes or hypertension local gastric diseases