Auricular Pressure for Postoperative Pain After Hemorrhoidectiomy: a Randomized Controlled Trial
Auricular Pressure for Postoperative Pain After Hemorrhoidectiomy: a Randomized Controlled Trial
Auricular pressure is effective for postoperative analgesia after hemorrhoidectomy, but the
 evidence is not sufficient.
This is a randomized, double-blind study to study the analgesic effect of auricular pressure
 pill on persistent pain after hemorrhoidectiomy. Baseline pain intensity scores (VAS>3) of
 the subjects will be collected 24 hours after the operation of the patients. Eligible
 subjects will be randomly assigned to receive auricular pressure pills or sham-auricular
 pressure pills. The treatment will last 5-7 days. Participants will receive auricular
 pressure once two days, and receive VAS, concomitant medication, PONV intensity scale and
 peripheral edema were recorded daily, and after the operation 24 hours, 3 days and 7 days the
 patients will receive anxiety and depression scale(HAD) , and VAS data will be collected by
 telephone at 3 and 6 months after the operation.

 The statistical analysis results will be subject to the full analysis set (FAS) results, and
 a sensitivity analysis will be performed comparing the per-protocol (PP). The main indicators
 will be analyzed by covariance analysis, with VAS results as the dependent variable, grouping
 as the random factor, and age, course of disease, surgical method and baseline as the
 covariables to correct the P value. The secondary indicator analgesic usage rate will be
 analyzed using logistic regression analysis. Whether analgesic will be used as a dependent
 variable, grouping as a random factor, and age, course of disease, surgical method and
 evaluation time point will be analyzed as covariables. Other outcome indicators will be
 analyzed by covariance analysis, and the model will be the same as that of the main
 indicators. P<0.05 considered as significant difference, and SPSS20.0 used for analysis.

 The purpose of this study was to seek high quality evidence-based medical evidence for
 intervention of auricular pressure pills on postoperative pain of hemorrhoidectomy.
Inclusion Criteria:

 1. Meet the diagnostic criteria of grade II-IV mixed hemorrhoids and meet the operation
 conditions;

 2. Age 18~65;

 3. External stripping and internal ligation of mixed hemorrhoids, general anesthesia or
 lumbar shu point anesthesia;

 4. VAS score ≥3 points after the implementation of analgesia pump;

 5. Improve clinical auxiliary examination and sign informed consent.

 Exclusion Criteria:

 1. Combined with inflammatory hemorrhoids, thrombotic hemorrhoids, perianal eczema,
 perianal abscess and other perianal diseases that affect the evaluation of curative
 effect;

 2. Combined with intestinal infectious diseases, intestinal polyps, rectal malignant
 tumors, etc;

 3. Combined with severe cardiovascular disease, immune deficiency, mental disorder, or
 severe liver and kidney dysfunction;

 4. Auricle skin lesions or auricle skin allergy to tape is difficult to tolerate
 treatment;

 5. Combined cognitive impairment could not complete the efficacy; evaluation;

 6. Pregnancy or planned pregnancy.