Comparison of CNB and Surgical Specimens for ER, PgR, HER2 Status and Ki67 Index in Invasive Breast Cancer.
Comparison of CNB and Surgical Specimens for ER, PgR, HER2 Status and Ki67 Index in Invasive Breast Cancer.
-  This is a prospective, single-center, non-randomized, non-controlled study.

 -  The estrogen receptor (ER), progesterone receptor (PgR), HER2 status and Ki67 index of
 CNB specimen are critical biomarkers for making neoadjuvant therapy strategy in invasive
 breast cancer. The concordance of these biomarkers between CNB and surgical specimen was
 varied in previous retrospective reports. The aim of this study is to determine the
 discordance of these biomarkers between CNB and surgical specimen and the influence of
 making treatment strategy by the discordance.
Inclusion Criteria:

 -  • histologically confirmed primary invasive breast cancer by core needle biopsy

 Exclusion Criteria:

 -  • pathological diagnosed ductal carcinoma in situ or microinvasive breast cancer by
 core needle biopsy

 -  patient plans to receive neo-adjuvant system therapy