The Dose-Response Relationship of Rocuronium in Patients Taking Pyridostigmine
The Dose-Response Relationship of Rocuronium in Patients Taking Pyridostigmine
Pyridostigmine is a medication that is used in certain heart rate and blood pressure
 conditions. This medication, as a side effect, is known to also cause changes in the junction
 between a nerve and muscle. The changes caused at the nerve muscle junction by pyridostigmine
 could alter the effect of muscle relaxants (a medication used during surgery and anesthesia).
 The investigators are conducting this study to see whether patients taking pyridostigmine are
 more or less sensitive to rocuronium (a muscle relaxing medication used during surgery).
No subjects enrolled. No data collected.
Inclusion Criteria:

 -  Patients who take pyridostigmine for any reason or those who are matched by age, sex
 and weight to subjects taking pyridostigmine

 -  Patients who will be administered rocuronium during elective procedures as standard
 clinical care.

 Exclusion Criteria:

 -  Allergy to rocuronium

 -  Known neuromuscular disorder, patients suffering from myasthenia gravis

 -  Subjects taking medications known to impact neuromuscular transmission (ex.
 gentamicin).