Impact of Art Therapy on Brain Connectivity in Recent Post-Stroke Aphasia
Impact of Art Therapy on Brain Connectivity in Recent Post-Stroke Aphasia
A stroke located in the left parieto-temporal junction is associated, in aphasic right-handed
 patients, with a poor prognosis for language recovery. The role of the right hemisphere in
 recovering post-stroke aphasia is still controversial. Our hypothesis, based on recent work
 in imaging, is that early activation of the right hemisphere linked to the practice of the
 visual arts could facilitate language recovery in extended posterior left strokes that
 completely disrupt language areas.
The investigators will evaluate, at inclusion and at 6 weeks, the reorganization of
 functional and structural brain connectivity maps before and after rehabilitation of aphasia
 with art therapy and standard orthophonic rehabilitation versus a control group that received
 only standard orthophonic rehabilitation.

 The investigators will include all consecutive patients with recent ischemic or hemorrhagic
 stroke with unilateral lesion(s) of the parieto-temporal left junction present on the
 Diffusion MRI (DWI) performed in acute phase at 24-48h.

 All patients will undergo 2 MRI with tensor diffusion sequences (structural connectivity) and
 fMRI (functional magnetic resonance imaging) resting state sequences (functional
 connectivity) at inclusion and 6 weeks after rehabilitation with or without art therapy.

 The investigators aimed to demonstrate that early activation of the right hemisphere related
 to the practice of the visual arts could facilitate the recovery of language in later strokes
 completely disrupting the language areas of the left hemisphere.
Inclusion Criteria:

 -  Patients with recent ischemic or haemorrhagic stroke with unilateral lesion (s) of the
 parieto-temporal left junction present on the Diffusion MRI (DWI) performed in acute
 phase at 24-48h

 -  Post stroke delay of 15 days to 2 months

 -  Existence of moderate to severe phasic disorders on Aphasia Rapid Test score (ART,
 score> 6, scale of 26 items)

 -  Patient able to read and understand French

 -  Rightful

 -  Normal and corrected vision and hearing

 -  Absence of pre-existing degenerative neurological disorder

 -  Patient having signed his consent

 -  Age ≥ 18 years

 Exclusion Criteria:

 -  Patients with contraindications to MRI or claustrophobic

 -  Patients under legal protection

 -  Patients with behavioral disorders or disabling neurovisual disorders making
 participation in art therapy impossible

 -  Mute patients, illiterate patients

 -  Patients leaving the neurological SSR department prematurely

 -  Patients not affiliated to a social security scheme

 -  Pregnant or lactating women.