Radiotherapy for Malignant Astrocytomas in the Elderly
Radiotherapy for Malignant Astrocytomas in the Elderly
A randomized trial comparing radiotherapy with supportive care in patients aged 70 years or
 older with newly diagnosed, histologically confirmed anaplastic astrocytoma or glioblastoma,
 and a Karnofsky performance status > 70.
Inclusion Criteria:

 -  Glioblastoma and anaplastic astrocytoma, supratentorial, histologically confirmed

 -  Brain CT scan or MRI within 28 days before surgery

 -  Age: 70 years or older

 -  Karnofsky performance status, 70 or more.

 -  Life expectancy over 12 weeks

 -  Informed consent

 Exclusion Criteria:

 -  Brain radiotherapy

 -  Chemotherapy

 -  Severe systemic disease