Investigating a Model for Acute Ischemic Pain in Humans
Investigating a Model for Acute Ischemic Pain in Humans
The pathophysiology of acute ischemic pain is not well established. The aim of the present
 study was to investigate acute ischemic pain in humans with a view to establish a scientific
 model to perform future studies. The investigators examined whether peripheral nerve damage
 and acute inflammation occur during short episodes of acute ischemia.
Inclusion Criteria:

 -  patients over 40 years

 -  unilateral femoral-popliteal PAD, Fontaine grade II

 Exclusion Criteria:

 -  patients with pain at rest or other pain origin

 -  diabetic polyneuropathy

 -  deep vein thrombosis