Human Anaplasmosis in Eastern France
Human Anaplasmosis in Eastern France
Anaplasmosis is a tick-borne transmitted infection. Its clinical expression include fever,
 cytopenia and hepatitis.This infection was initially described in United States. In Europe,
 its epidemiology is not well known. Some isolated cases have been diagnosed in several
 country, were the tick Ixodes ricinus is known to transmitted another infection :the Lyme
 borreliosis.The purpose of our study is to look systematically for Anaplasmosis, in patient
 living in Eastern France, and presenting with compatible clinical symptoms using a new
 diagnosis tool : PCR in blood samples. So we will have new data about epidemiology in our
 country and the clinical symptoms that are associated with Anaplasmosis.
Inclusion Criteria:

 -  patient with at least one of following symptoms : fever or muscular pain or articular
 pain or respiratory signs or neurological signs or meningitis or erythema occurring
 during the three weeks after a tick bite-

 -  Or

 -  patient with fever with at least one of following criteria : thrombocytopenia,
 leucopenia, hepatitis, without any other cause that can explain these abnormalities.

 -  Or

 -  patient with tick-borne encephalitis, or primary stage Lyme borreliosis

 Exclusion Criteria:

 -  children less that 10 years

 -  pregnancy

 -  patients with an other diagnosis that can explain clinical symptoms or biological
 abnormalities

 -  antibiotherapy with cyclins during the days before inclusion