Micromegaly and Discrepancy Between Growth Hormone and IGF1 at the Diagnosis and Follow-up of Acromegalic Patients
Micromegaly and Discrepancy Between Growth Hormone and IGF1 at the Diagnosis and Follow-up of Acromegalic Patients
The diagnosis and the follow-up of acromegalic patients are based on the mesurement of Growth
 hormone (GH) and IGF1 rates. However, the literature described some cases of patient for whom
 the investigators observed a discrepancy between GH and IGF1 rates. Since the acromegaly is a
 rare disease and this phenomenon concerns about 30% of these patients, there is a lack of
 investigations about consequences that this discordance may induces. In this study, the
 investigators aimed at assessing if patients with discordance between GH and IGF1 rates
 present a different risk of recurrence and complications related to acromegaly, from patients
 with concordant results.
Inclusion criteria:

 -  Acromegaly followed up in one of the center (Montpellier, Nimes or Béziers hospital,
 independent endocrinologist) between 2010 and 2021

 -  Age over 18 years old

 -  Measurement of GH and IGF1 rates at the last visit control available

 Exclusion criteria:

 -  Lost to follow-up

 -  Status about complications related to acromegaly unknown