National Study on the Interest of EEG-fMRI in the Presurgical Evaluation of Partial Epilepsies Drug
National Study on the Interest of EEG-fMRI in the Presurgical Evaluation of Partial Epilepsies Drug
The main goal of this study is to evaluate the additional value of EEG-fMRI method in the
 presurgical evaluation of focal intractable epilepsy.

 To consider a patient for surgery, the main difficulty is to define accurately the
 epileptogenic zone. This definition is complex and is often supported by several types of
 exploration (MRI, FDG PET, neuropsychological testing, video-EEG...). In this study we will
 evaluate the adding value of the simultaneous recording of EEG and fMRI in the epileptogenic
 zone definition.
Inclusion Criteria:

 -  > 8 years old

 -  intractable focal epilepsy

 -  presurgical evaluation or "phase 1" planified

 -  with focal EEG activity : more than 3 EEG interictal epileptic events per hour

 -  patient and/or legal representant given their written consent for their participation
 in the study

 Exclusion Criteria:

 -  MRI contraindication

 -  pregnancy

 -  uncomfortable prolonged lying position

 -  frequent primary or secondary generalised seizure with tonic clonic movements (>2 per
 week)

 -  previous epilepsy surgery

 -  important mental retardation