Safety and Efficacy Study of a New Device for Making Neochordae in Mitral Valve Repair
Safety and Efficacy Study of a New Device for Making Neochordae in Mitral Valve Repair
Mitral prolapse is a common cardiac disease whose patients are at higher risk for serious
 complications. Mitral valve (MV) repair offers several important advantages compared with
 valve replacement and it achieves excellent midterm and long-term results. Two major problems
 of using pre-measured expanded polytetrafluoroethylene(ePTFE) neochordae (the loop technique)
 are deciding the length of the neochordae and tying the knot at the intended length.
 Therefore, a great need still exists to find new method to simplify and precise the length of
 neochordae. 20 patients with mitral valve prolapse who undergo mitral valve repair using
 neochorda will be recruited in this study. Trans thoracic echocardiography (TTE) will be done
 preoperatively for all patients. Two, three, and four chamber view of each patient will be
 pre-operatively recorded. The device will be set with extracted measurements. Artificial
 corda loops are made using CV-4 ePTFE sutures. After artificial chordae replacement, the ring
 annuloplasty will be done. Follow up: A leakage test after attaching the 1st loop; Post
 operative trans esophageal echocardiography (TEE) and determining the severity of mitral
 regurgitation [Wall motion Score Index (WMSI), Mitral Annulus Area (MAA), LVEF, End Systolic
 Volume (ESV), End Diastolic Volume (EDV), Iso-Volemic Relaxation Time (IVRT), (IVRT/(QE-QE^')
 ,Chamber Relaxation velocity)/(Myocard relaxation velocity(E/E^' ), HR]; TEE 3 months after
 discharge; Cross clamp time; Intubation period in ICU.
Inclusion Criteria:

 -  Patients with Mitral valve prolapse who undergo mitral valve repair using neochorda

 Exclusion Criteria:

 -  Nothing