Muscle Tenderness and Hardness in Migraine Patients
Muscle Tenderness and Hardness in Migraine Patients
The aim of the study is to examine symptomatology, quantitative sensory test (QST)
 parameters, muscle tenderness and muscle hardness in migraine patients interictally and
 compare with healthy controls
Migraine patients exhibit different symptomatology and responses to treatment. For example do
 many migraine patients have neck symptoms, despite they apparently do not have any neck
 disorders.Furthermore the response to treatment differs between patients. Differences in
 symptomatology, QST parameters and muscle stiffness can be used to subdivide and phenotype
 migraine patients.

 The investigators are examining migraine patients with:

 A semistructured interview, Quantitative sensory testing (cold pain threshold, heat pain
 threshold and Pin Prick), Muscle tenderness (total tenderness score, local tenderness score
 and stimulus response curve), and muscle hardness with ultrasound elastography. All tests are
 performed the same day
Inclusion Criteria:

 -  Migraine Patients from the Danish Headache Centre. Migraine classified using the
 International Classification of Headache Disorders (ICHD3) criteria.

 Exclusion Criteria:

 -  Pregnant or lactating women

 -  Musculoskeletal injuries in the neck or shoulder

 -  Other primary headache disorders than migraine or Tension Type Headache

 -  On the time of examination: Migraine free for at least 48 hours

 -  On the time of examination: haven't trained the upper body for at least 48 hours

 -  On the time of examination: haven't used painkillers for at least 48 hours

 Healthy controls:

 Exclusion Criteria:

 -  Pregnant or lactating women

 -  Musculoskeletal injuries in the neck or shoulder

 -  Migraine disorders

 -  1. degree relatives with migraine disorders

 -  Over 1 day of tension type headache a month.

 -  On the time of examination: haven't trained the upper body for at least 48 hours

 -  On the time of examination: haven't used painkillers for at least 48 hours