The Research of the Evaluation of Clinical Procedures in Gastroesophageal Varices in Patients With Liver Cirrhosis
The Research of the Evaluation of Clinical Procedures in Gastroesophageal Varices in Patients With Liver Cirrhosis
The purpose of this study is to evaluate the efficacy of two different endoscopic treatment
 in gastroesophageal varices in patients with liver cirrhosis: ligation versus ligation plus
 sclerotherapy in addition to cyanoacrylates
Gastroesophageal variceal bleeding, which often results from portal hypertention, is known as
 one of the most frequent death causes of patients with liver cirrhosis. When a patient has
 bleeding episode, it's very likely that he/she will develop another one in the future.
 Endoscopic treatments such as ligation, sclerotherapy or cyanocrylates are proved to decrease
 the risk of re-bleeding. The purpose of this study is to evaluate the efficacy of two
 different endoscopic treatments in patients who have both gastric and esophageal varices with
 liver cirrhosis: In addition to cyanoacrylates, ligation versus ligation plus sclerotherapy.
Inclusion Criteria:

 -  Patients with portal hypertension caused by liver cirrhosis who presented with an
 acute or recent episode of gastroesophageal variceal bleeding and have previously
 received endoscopic treatments of ligation and cyanoacrylate. Diagnosis of liver
 cirrhosis or mixed cirrhosis was based on results of liver biopsy or biochemical tests
 and liver imaging by ultrasonography.

 -  The extent of the varices range from Moderate to Severe.

 -  The age of the patients range from 18 to 72 years old.

 Exclusion Criteria:

 -  Patients who had other causes for portal hypertention(CTPV,Budd-Chiari syndrome,etc.)

 -  Patients with severe systemic disease (renal failure, heart failure,carcinoma other
 than liver cancer,etc.)

 -  Patients who had contraindications for ligation,sclerotherapy or cyanoacrylate.

 -  Patients who have previously received shunt or devascularization operation,TIPS.

 -  Patients who had portosystemic shunt according to the results of CT scan.