A Registration Study on Depression in Patients With Epilepsy
A Registration Study on Depression in Patients With Epilepsy
The prevalence of comorbid depression in patients with epilepsy is as high as 30-50%. The
 depressive symptoms severely affect seizure severity and quality of life in patients with
 epilepsy. The aim of this study is to register the diagnosis and treatment for depression in
 patients with epilepsy from the East China, determining the incidence rate of comorbid
 depression in patients with epilepsy and the choices for the antidepressant treatment. At the
 same time, neuroimaging data such as brain MRI and blood sample will be collected to analyze
 some biomarkers for the comorbidity of epilepsy and depression.
Inclusion Criteria:

 -  At least 1 or more seizures with evidences demonstrated by EEG

 Exclusion Criteria:

 -  Severe psychotic symptoms such as hallucination and delusions

 -  Progressive central nervous system diseases such as acute stroke, brain malignant
 tumors, encephalitis, and Parkinson's disease etc.

 -  Severe cardiac, pulmonary, hepatic, and renal diseases

 -  Severe cognitive dysfunctions and physical disabilities