Safety and Efficacy of NVXT Solution in Mild-to-Moderate Fungal Infection of the Toe Nail
Safety and Efficacy of NVXT Solution in Mild-to-Moderate Fungal Infection of the Toe Nail
This study will examine the safety, tolerability and efficacy of NVXT in a new formulation in
 patients with mild-to-moderate fungal infection of the toe nail.
This Phase IIa pilot multiple-dose study will examine the safety, tolerability and efficacy
 of NVXT in a new formulation in patients with mild-to-moderate fungal infection of the toe
 nail.
Inclusion Criteria:

 -  Clinically diagnosed onychomycosis

 -  Presence of dermatophyte fungal infection with no current topical or systemic
 antifungal therapy

 -  Clinical diagnosis of mild-to-moderate fungal infection of at least one toe involving
 10-50% of the nail area, without involvement of one of the lunular proximal regions

 -  Positive potassium hydroxide mount preparation

 -  Positive fungal culture for a dermatophyte

 Exclusion Criteria:

 -  Nail or anatomical abnormalities of the toe that may interfere with evaluations or
 dosing compliance