Clinical Study on the Harvesting Lymph Nodes With Carbon Nanoparticles for Advanced Gastric Cancer
Clinical Study on the Harvesting Lymph Nodes With Carbon Nanoparticles for Advanced Gastric Cancer
Carbon Nanoparticles (CNP),with a mean size of 150 nm,can be taken up selectively by
 lymphatics after injection into the tissue and draining regional lymph nodes are thereby
 colored black,which may provide surgeons the guidance to lymph node dissection and help them
 harvest lymph nodes after surgery,especially some small ones. but there was insufficient
 evidence to justify its efficacy for those purposes.Therefore,the investigators carried out a
 prospective randomized controlled trial on lymph node vital staining for lymph node
 dissection and harvesting in advanced gastric cancer to test this idea.
Carbon Nanoparticles (CNP),with a mean size of 150 nm,can be taken up selectively by
 lymphatics after injection into the tissue and draining regional lymph nodes are thereby
 colored black,which may provide surgeons the guidance to lymph node dissection and help them
 harvest lymph nodes after surgery,especially some small ones. but there was insufficient
 evidence to justify its efficacy for those purposes.Therefore,the investigators carried out a
 prospective randomized controlled trial on lymph node vital staining for lymph node
 dissection and harvesting in advanced gastric cancer to test this idea.
Inclusion Criteria:

 -  Histologically and CT confirmed resectable advanced gastric cancer

 -  No prior treatment

 -  No metastases

 Exclusion Criteria:

 -  Having allergic reaction

 -  Pregnant

 -  R0 resection is not achieved by gastrectomy with D2 lymphadenectomy according to
 Japanese gastric cancer treatment guidelines 2010 (ver. 3)