Multidisciplinary Support Program in Chronic Hepatitis C
Multidisciplinary Support Program in Chronic Hepatitis C
Adherence to antiviral treatment in chronic hepatitis C (CHC) is an important factor to
 achieve sustained virological response (SVR). The aim of our study is to evaluate the
 efficacy of a multidisciplinary support program (MSP) in adherence to and efficacy of
 pegylated interferon alfa-2a and ribavirin compared to the conventional approach. We assessed
 447 patients with CHC receiving antiviral treatment distributed into 3 groups: control group
 (recruited 2002-2004, n= 147), MSP-pilot group (recruited 2005-2006, n=131), and
 MSP-validation group (recruited 2007-2009, n=169).
Adherence to antiviral treatment in chronic hepatitis C (CHC) is an important factor to
 achieve sustained virological response (SVR). The aim of our study is to evaluate the
 efficacy of a multidisciplinary support program (MSP) in adherence to and efficacy of
 pegylated interferon alfa-2a and ribavirin compared to the conventional approach. We assessed
 447 patients with CHC receiving antiviral treatment distributed into 3 groups: control group
 (follow-up 2002-2004, n= 147), MSP-pilot group (follow-up 2005-2006, n=131), and
 MSP-validation group (follow-up 2007-2009, n=169).A cost-effectiveness analysis was performed
 using a Markov model.
Inclusion Criteria:

 -  Patients with chronic hepatitis C eligible to receive antiviral treatment.

 Exclusion Criteria:

 -  Patients who had undergone previous antiviral treatment, those with human
 immunodeficiency virus (HIV) or hepatitis B virus (HBV) co-infection, and individuals
 included in other treatment protocols.