Gaming Console Home-Based Exercise for Adults With Cystic Fibrosis
Gaming Console Home-Based Exercise for Adults With Cystic Fibrosis
Physical activity and exercise have become an accepted and valued component of cystic
 fibrosis care. Regular physical activity and exercise can slow the rate of decline of
 pulmonary function, improve physical fitness, and enhance quality of life. However,
 motivating people to be more active is challenging. Supervised, facility-based exercise
 programs are expensive and labor intensive (since groups of patients with CF cannot exercise
 together in the same physical location). Home-based exercise using an interactive exergame
 device may be an effective way to improve adherence to an exercise program for patients with
 CF. Therefore, the primary objective of this study is to evaluate the effects of a 12-week,
 home-based exergame exercise intervention on aerobic capacity (peak VO2). The secondary
 endpoint is nasal potential difference, an indicator of how well sodium and chloride flow
 across the mucous membranes in the nose. Other outcomes include patient-reported quality of
 life and habitual physical activity level. Following baseline assessments participants will
 be begin a 12 week, partially-supervised exercise program consisting of at least 90 minutes
 per week of aerobic and resistance exercise training using the Nintendo Wii Fit Plus
 exergaming device. Participants will receive at least monthly follow-up phone calls to
 provide additional exercise counseling and motivation. After 12 weeks, they will continue
 with the exergame intervention for another 12 weeks, but without external supervision.
Inclusion Criteria:

 -  confirmed diagnosis of CF

 -  currently sedentary (<60 min/week of physical activity)

 -  stable clinical condition (no exacerbation in last 6 weeks)

 Exclusion Criteria:

 -  nasal surgery for polyposis in the past 2 years

 -  participating or have participated (in the past 30 days) in another clinical trial
 which can affect the outcomes of the proposed study

 -  unable to read/speak English

 -  recurrent pneumothorax (in the past 6 months)

 -  hemoptysis (hospitalized in the past 6 months)

 -  uncontrolled CF-related diabetes (HbA1c > 10%)