Genetic Polymorphisms of Interleukin-10 and TNF-α on Outcome of HCV-Related Chronic Liver Disease
Genetic Polymorphisms of Interleukin-10 and TNF-α on Outcome of HCV-Related Chronic Liver Disease
The prognosis of chronic hepatitis C virus (HCV)infeciton varies from minimal progressive
 disease to cirrhosis or hepatocellular carcinoma. Host genetic factors contribute to disease
 severity. It is known that cytokine gene (including tumor necrosis factor-alpha (TNF-alpha)
 and interleukin-10 (IL-10) polymorphism affect disease prognosis.This study aims to assess
 the effect of TNF-alpha and IL-10, and their interaction,on prognosis of HCV-related chronic
 liver disease
Inclusion Criteria:

 -  Anti-HCV-positive patients

 Exclusion Criteria:

 -  Anti-HCV-negative patients