Study Investigating the Effects of UVC Beam and Laser Beam Therapy According to Standard Therapy in Patients With Covid-19 Diagnosis
Study Investigating the Effects of UVC Beam and Laser Beam Therapy According to Standard Therapy in Patients With Covid-19 Diagnosis
Clinical research study that evaluates the effect of Turkish Beam-Selective UV developed by
 RD GLOBAL ARAŞTIRMA GELİŞTİRME SAĞLIK İLAÇ İNŞAAT YATIRIMLARI A.Ş. use into Intravascular,
 Intrapulmonary, Intratracial, Intrarespiratory area. Bacteria, Fungal and Virus-based
 pathogens systematically to collect and evaluate specific clinical performance and safety
 data.

 This Clinical Research aims to investigate the effectiveness of the treatment group and
 control group mortality rates, intensive care hospitalization times, monitoring the virus
 load by PCR, and the treatment effectiveness of UVC application.

 This Clinical Research covers determining the treatment effectiveness and reliability of UVC
 application to patient groups, the details of which are determined in the protocol.
DESIGN

 Prospective, parallel, multicentre, randomized controlled study Ages between 40 and 75 years
 of age and positive symptoms such as fever, malaise, cough, and shortness of breath, or
 positive atypical pneumonia in CT findings or COVID-19 (SARS-CoV-2) test In the intensive
 care unit, which is accepted as COVID 19 infection and has been treated, patients will be
 treated with UVC radiation and laser beam treatment according to IKU principles in addition
 to Antimalarial therapy + Antiviral therapy + Anitibiotic therapy. Standard treatment
 consisting of Antimalarial therapy + Antiviral therapy + Antibiotic therapy will be applied
 to the control group. The dosage of the standard treatment consisting of antimalarial therapy
 + Antiviral therapy + Anitibiotic therapy, the number of days of treatment, and its active
 ingredient are indicated in the table.
Inclusion Criteria:

 -  Respiratory rate ≥ 30

 -  Dyspnea and breathing difficulties findings

 -  Cases with oxygen saturation below 90% despite nasal oxygen support of 5 liters /
 minute and above

 -  Cases with partial oxygen pressure below 70 mmHg despite nasal oxygen support of 5
 liters / minute and above

 -  PaO2 / FiO2 <300 Lactate> 4 mmol / L Bilateral infiltrations or multi-lobar
 involvement on chest x-ray or tomography

 -  Hypotension (systolic blood pressure <90 mmHg,> 40 mmHg drop from usual SKB, mean
 arterial pressure <65 mmHg)

 -  Skin perfusion disorder Organ dysfunction such as kidney function test, liver function
 test disorder, thrombocytopenia, confusion Presence of immunosuppressive disease-
 Presence of uncontrolled comorbidity with more than one feature

 -  Troponin height, arrhythmia

 -  COVID 19 Test positivity

 Exclusion Criteria:

 -  Under 40 years old

 -  Pregnant women and those with suspected pregnancy

 -  Those with a history of anaphylaxis

 -  Those with known DNA repair deficiencies:

 -  Those diagnosed with mental disorder,

 -  puerperant women and lactating women