Heparin vs Placebo for Cardiac Catheterization
Heparin vs Placebo for Cardiac Catheterization
Patients undergoing cardiac catheterization will be randomized to 3 groups: no anticoagulant,
 low dose anticoagulant and high dose anticoagulant.
Patients undergoing diagnostic cardiac catheterization via the trans-radial approach will be
 randomly allocated (1:1:1) to receive either low-dose UFH (25 IU/Kg -maximal dose 3,000 IU),
 high-dose UFH 50 IU/kg -maximal dose 5,000 IU) or N/S 0.9%. After 30 minutes, patients will
 undergo a gradual wrist band release. Hematoma and radial artery occlusion will be assessed.
Inclusion Criteria:

 -  diagnostic cardiac catheterization; Small size sheath; patency of the ulno-palmar
 circulation

 Exclusion Criteria:

 abnormal ulno-palmar circulation; Prior radial artery thrombosis; Prior surgery close to
 the access site; Emergent cardiac catheterization; History of HIT or allergy to heparin;
 Patients requiring anticoagulation