S.A.F.E.BT System Extracorporeal Treatment With DIAPACT CRRT
S.A.F.E.BT System Extracorporeal Treatment With DIAPACT CRRT
The purpose of this study is to determine if Selective Adsorption System for Removal of
 Bacterial Toxins (S.A.F.E.BT) therapy is effective in the treatment of severe sepsis.
Is extracorporeal treatment effective in the treatment of sepsis
Inclusion Criteria

 -  Clinical diagnosis of Sepsis

 -  Mechanical ventilation due to acute pulmonary dysfunction

 -  One additional (second) acute sepsis-related organ dysfunction

 Exclusion Criteria

 -  Pregnant women and nursing mothers

 -  Conditions or medications associated with an increased risk of bleeding/complications
 from anticoagulation

 -  Previous episode of sepsis during this hospitalization

 -  PaO2/FiO2 ratio < 300

 -  Severe granulocytopenia (leukocytes <500 / μl)

 -  Acute hepatic diseases or severe liver failure or cirrhosis

 -  Chronic cardiovascular disease precluding extracorporeal treatment

 -  Human immunodeficiency virus complicated by AIDS defining illness

 -  Evidence of active bleeding - uncontrolled hemorrhage