A Novel Myocardial Impedance Mapping System for Ablation of Post-infarction Ventricular Arrhytmias in Humans
A Novel Myocardial Impedance Mapping System for Ablation of Post-infarction Ventricular Arrhytmias in Humans
Precise identification of the infarct scar is essential for successful catheter ablation of
 ventricular arrhythmias in patients with chronic myocardial infarction. Voltage mapping of
 endocardial electrograms is currently used to delineate the necrotic scar but this is
 influenced by the direction of the activation wave front and is not sensitive enough to
 differentiate distinct degrees of transmural injury in the scar. Mapping of local myocardial
 electrical impedance may overcome these limitations.
Clinical series: Patients with chronic infarction undergoing catheter ablation of ventricular
 arrhythmias will be submitted to mapping of both voltage and tissue impedance. Likewise, the
 accuracy of the two maps identifying the extent and transmurality of the infarction will be
 assesssed by gadolinium imaging. The impedance system is already constructed and certified
 for clinical research use.
Inclusion Criteria:

 -  More than 18 yearts

 -  Chronic myocardial infarction

 -  Undergoing ventricular ablation of ventricular arrhythmias

 Exclusion Criteria:

 -  patients with device not suitable for cardiac magnetic ressonance (CMR)

 -  pregnacy