the Effect of Calcium Dobesilate on Non Dialysis Patients With CKD
the Effect of Calcium Dobesilate on Non Dialysis Patients With CKD
To investigate the feasibility of calcium dobesilate in the treatment of microvascular injury
 provides new ideas and theoretical basis for the prevention and treatment of chronic renal
 failure.
The deterioration of renal function is closely related to microvascular damage, calcium
 dobesilate is known as microcirculation protective agent, the investigators will further
 study its effect of non dialysis patients with chronic renal failure and explore the
 feasibility of calcium dobesilate in treatment of renal microvascular injury, the
 investigators will provide new ideas and theoretical basis for the prevention and treatment
 of chronic renal failure.
Inclusion Criteria:

 -  Enroll the non dialysis patients with chronic renal failure hospitalized in the
 Department of Nephrology of the Affiliated Hospital of Xuzhou Medical University.

 -  According to the glomerular filtration rate, the patients who were not required to be
 dialysate were at CKD3-5 (GFR between 10 and 59ml/min).

 Exclusion Criteria:

 -  Exclude those patients with diabetes, cardiovascular disease, severe infection, shock,
 dehydration, abnormal liver function, received glucocorticoid therapy, surgery and
 emergency dialysis.

 -  Eliminate those patients with respiratory disease(such as chronic obstructive
 pulmonary disease, bronchiectasis, asthma), cardiovascular diseases(such as acute and
 chronic cardiac insufficiency), blood system diseases (such as aplastic anemia,
 nutritional anemia and polycythemia vera).