An Epidemiological Study on Antimicrobial Treatment of Nosocomial Infections in Clinical Practice
An Epidemiological Study on Antimicrobial Treatment of Nosocomial Infections in Clinical Practice
The present study is a retrospective cohort study on patients who suffered a nosocomial
 infection in major hospitals in Vietnam. Data relating to patient demography include age,
 gender; medical history; APACHE II score; background conditions, infection details and
 antimicrobial therapy; and all-caused mortality, time of hospitalization and intensive care.
 The investigators hypothesis is that antimicrobial treatment inappropriate is highly
 dependent on incidence of antibiotic resistant pathogens, nonfermentative Gram-negative
 bacilli and ESBL-producing enterobacteriaceae spp. Variables are demographic characteristics,
 background conditions, immunosuppressive therapy, antimicrobial susceptibility and
 inappropriate treatment is explored as possible predictors of mortality.
Inclusion Criteria:

 -  Patient was diagnosed as nosocomial infection defined according to criteria
 established by the US CDC. The diagnosis criteria for ventilator-associated pneumonia
 are modified from those established by the American College of Chest Physicians.

 -  Patient received empiric antimicrobial therapy within 24 hour from onset of infection
 and had antimicrobial susceptibility.

 Exclusion Criteria:

 -  A patient was in part of a controlled clinical trial for the current infection
 episode.

 -  Patients with suspected infections by virus or fungus or tuberculosis will be
 excluded.