Eye-ECG Approach to Emergencies : Diagnostic Performance of the HINTS Test
Eye-ECG Approach to Emergencies : Diagnostic Performance of the HINTS Test
Vertigo integrated with acute vestibular syndrome (AVS) is a frequent reason for emergency
 visits. The French and international literature estimates between 2 to 4% of vertigo
 prevalence among reasons for coming to emergencies. International classifications define AVS
 as vertigo or acute dizziness (less than one month) and persistent, gait instability, nausea
 or vomiting, nystagmus or an intolerance to head movements.

 In emergency departments, the clinical approach of vertiginous patients is difficult because
 the "vertigo" term is sometimes used in by patients, or because they use the terms
 "uneasiness", "vertigo", or "dizziness" without distinction. These terms sometimes include
 various sensations of "sleeping head", "blurred vision", "instability", "pitch" etc. A first
 difficulty is therefore to clarify these terms and organize syndrome expressed by the
 patient. A rigorous interrogation is therefore essential and can be time-consuming.

 Another difficulty is to carry out an exhaustive clinical examination including the
 assessment of the general condition and hydration, an ENT examination and a neurological
 examination. However, at the end of these steps, the orientation central or peripheral
 etiology is not simple. In the last consensus conference of the Barany Society (2014) the
 classification of VAS into three types was not sufficient to distinguish "benign" vertigo
 from "risky" dizziness (related to a central cause).
The HINTS test (Head Impulse, Nystagmus, Test of Skew) is a clinical test composed of 3
 oculomotor examinations: the search for high frequency vestibulo-ocular reflex during a
 passive impulse of the head (Head Impulse test), the detection of a spontaneous nystagmus and
 a vertical divergence. It has been developed to evaluate patients with AVS defined as vertigo
 or acute and persistent dizziness sometimes accompanied by nausea or vomiting, and/or gait
 instability, and/or nystagmus, and/or intolerance to head movements. This time saving is
 important, as a complete neurological examination usually takes between 10 and 15 minutes.
 The presence of at least one of the three items of central locator value is sufficient to
 diagnose a central cause of AVS, including normal early brain imaging. Some studies suggest
 that absence of these three criteria does not require an emergency neuroimaging examination
 and allows ambulatory management of the patient, in search of a peripheral cause of the ENT
 sphere.

 The STANDING clinical algorithm (SponTAneous, Nystagmus, Direction, head Impulse test,
 STANDING) was proposed by Vanni in 2015 for diagnosis of the AVS central causes in
 emergencies in a one-year prospective Italian monocentric study. The STANDING algorithm
 consists of clinical elements that can be evaluated in about 10 minutes at the patient's
 bedside: two oculomotor examinations (Head Impulse Test and detection of a nystagmus),
 detection of ataxia and practice of release maneuvers.

 Currently, the patient management with isolated AVS in the emergency room lacks an ideal
 diagnostic clinical test: efficient, non-invasive, inexpensive and painless.

 The investigators would like to know what diagnostic performance of the HINTS test
 (sensitivity and specificity) is when it is performed by emergency physicians on a population
 of patients with isolated AVS in emergency room. They can thus either be part of non-urgent
 outpatient care in the event of suspicion of a peripheral cause of the ENT sphere, or part of
 rapid and aggressive inpatient neurological care in the event of suspicion of a central
 cerebral cause.
Inclusion Criteria:

 -  French-speaking patient.

 -  Affiliated with social security or, failing that, with another health insurance
 system.

 -  Patient capable of giving free, informed and express consent

 -  Patient with an isolated AVS defined by a progression of more than one hour and less
 than one month and at least one of the following criteria:

 -  Vertigo (illusion of the subject moving in relation to surrounding objects or objects)
 surrounding with respect to the subject, a sensation of rotation, movement of the body
 in the plane vertical, unstable, described as a pitch or "rotating head"), sometimes
 associated with vegetative signs (nausea, vomiting, pallor, sweating, slowing of
 frequency cardiac),

 -  A nystagmus (spontaneous or positional),

 -  Ataxia characterized by gait disorders with imbalance type (which can dominate the
 symptomatology) with sways, a brittle gait or simple instability.

 A patient may be included several times during the study period provided that they are
 acute episodes separate.

 Exclusion Criteria:

 -  Patient with focal neurological signs concomitantly appearing with AVS: disorder of
 the language or writing, speech impairment, dysarthria, movement performance disorders
 voluntary, sensory motor deficit, involuntary abnormal movements. The vertiginous
 patients with ataxia meet the inclusion criteria provided they do not show any other
 sign neurological focal, in particular, other signs of cerebellar syndrome.

 -  Patient with a Glasgow score <15 or blood glucose < 0.70 g/l, MAP < 65 mm Hg, acute
 anemia and <7g/dl, transient dizziness having disappeared upon arrival in the
 emergency room, acute alcohol abuse, acute alcohol abuse, and acute drug intoxication,
 a history of oculomotor paralysis.

 -  Patient under guardianship or curatorship.

 -  Patient deprived of liberty.

 -  Patient under the protection of justice.