BLOSSOM: Behavioral Modification and Lorcaserin Second Study for Obesity Management
BLOSSOM: Behavioral Modification and Lorcaserin Second Study for Obesity Management
The purpose of this study is to assess the weight loss effect of lorcaserin during and at the
 end of 1 year of treatment in overweight and obese patients.
Randomized, double-blind, placebo-controlled, parallel-group assessment of the effects of
 lorcaserin hydrochloride during 52 weeks of administration to overweight or obese male and
 female volunteers aged 18 to 65 years inclusive.
Inclusion Criteria:

 -  Overweight and/or obese men and women with a body mass index (BMI) 30 to 45 kg/m2 with
 or without a comorbid condition (e.g., hypertension, dyslipidemia, CV disease, glucose
 intolerance, sleep apnea), or 27 to 29.9 kg/m2 with at least one comorbid condition.

 -  Ability to complete a 1 year study

 Exclusion Criteria:

 -  Pregnancy

 -  Diabetes mellitus (type I, II or other)

 -  History of symptomatic heart valve disease

 -  Serious or unstable current or past medical conditions