Allogenic Cord Blood Transfusion in Patients With Autism
Allogenic Cord Blood Transfusion in Patients With Autism
Autism is one of those disorders in Autism spectrum disorders (ASD), which characterized by
 social interaction abnormalities, impaired verbal and non-verbal communication, and
 repetitive, obsessive behavior, while the therapeutic effect of current treatments remains
 limited progress.

 The possible reason for ASD is neural hypoperfusion and immune deregulation. The Human
 Umbilical Cord Blood Mononuclear Cells (hUCB-MNCs) have been shown to have the ability to
 modulate the immune response and enhance angiogenesis, suggesting the novel and promising
 therapeutic strategy. In this study, the safety and efficacy of hUCB-MNCs infusion will be
 evaluated in patients with Autism.
Autism Spectrum Disorders (ASD) are heterogeneous neuro-developed disorders. Autism is the
 most common disorder of the diseases characterized by dysfunctions in response social
 interaction and communication, as well as the presence of repetitive and stereotyped
 behaviors. Recent reports of a sharp increase in the number of children with autism. The
 exact etiology of autism remains unclear. Compliance, the definition of effective treatments
 for autism is particularly difficult.

 Although it has been understood, it can be a question of immune dysregulation. Examination of
 the inflammatory cytokines, dysfunction of the immune system and the immune system. The Human
 Umbilical Cord Blood Mononuclear Cells (hUCB-MNCs) have been shown to have the ability to
 modulate the immune response and enhance angiogenesis, suggesting the novel and promising
 therapeutic strategy. The Our study suggest that infusion of cord blood mononuclear cells
 will affect Autism.
Inclusion Criteria:

 -  Confirmed diagnosis: autistic type disorder (ASD).

 -  Systemic speech underdevelopment

 -  The presence of attention deficit hyperactivity disorder as a comorbid state

 -  Cognitive impairment

 Exclusion Criteria:

 -  organic pathology of the brain according to CT, MRI

 -  the presence of the following diseases in history: heart failure in the stage of
 decompensation, stroke in history less than 1 year ago, blood diseases;

 -  decompensation of chronic and endocrinological diseases;

 -  acute respiratory viral and bacterial infections, period less than 1 month after the
 acute phase.

 -  HIV infection, hepatitis B and C.

 -  oncological diseases, chemotherapy in the anamnesis;

 -  tuberculosis.

 -  Severe form of intellectual disability.

 -  Cerebral palsy.

 -  epilepsy.