Comparison Study of Different Tumor Biopsy Method for Sentinel Lymph Node Biopsy in Breast Cancer
Comparison Study of Different Tumor Biopsy Method for Sentinel Lymph Node Biopsy in Breast Cancer
Sentinel lymph node biopsy (SLNB) has become a mainstay surgery method in breast cance, and
 the identified number of sentinel lymph nodes determines its accuracy for axillary status.
 Retrospective study indicated that preoperative tumor biopsy results in more detected
 sentinel lymoh nodes. The clinical trail is designed to compare the effect of three tumor
 biopsy methods (preoperative vacuum-assisted biopsy, core needle biopsy, and intraoperative
 excisional biopsy) for sentinel lymph nodes.
OBJECTIVES:

 Compare the identification rate of sentinel lymph node in breast cancer patients with
 different tumor biopsy methods.

 Evaluate the false-negative rates of sentinel lymph nodes in patients with different tumor
 biopsy methods.

 OUTLINE:

 The patients were randomly divided into three group, vacuum-assisted biopsy, core needle
 biopsy, and intraoperative excisional biopsy. Preoperative vacuum-assisted biopsy and core
 needle biopsy were performed in 10 days before the final surgery. All patients received dual
 tracer (radiolabeled colloid and blue dye) guided SLNB.
Inclusion Criteria:

 -  clinically lymph node negative breast cancer patients T1-T3

 Exclusion Criteria:

 -  history of breast cancer locally advanced breast cancer and metastatic breast cancer
 proven axillary lymph node metastasis history of axillary excisional or incisional
 biopsy, or dissection history of neoadjuvant chemotherapy pregnancy non-consented
 patients