Intraoperative Ultrasound in Patients Undergoing Transsphenoidal Surgery for Pituitary Adenoma
Intraoperative Ultrasound in Patients Undergoing Transsphenoidal Surgery for Pituitary Adenoma
Pituitary adenoma can be difficult to cure with approximately a third of patients in
 contemporary series' undergoing incomplete resection. Over the last decade or so a handful of
 groups have described the use intraoperative ultrasound to improve resection. Although
 limited, these proof-of-concept studies suggest intraoperative ultrasound is a safe and
 effective technological adjunct to transsphenoidal surgery for pituitary adenoma.

 In this prospective development study 30 adult patients will undergo transsphenoidal surgery
 for pituitary adenoma with prototype intraoperative ultrasound devices. The primary outcomes
 will be technical feasibility and device safety. The secondary outcomes will be complete
 versus incomplete radiological resection, endocrinological remission, the occurrence of
 postoperative complications, operating time, and length of stay.
Inclusion Criteria:

 -  adult patients

 -  undergoing transsphenoidal surgery

 -  diagnosis of pituitary adenoma on pre-operative MRI

 -  able to provide consent

 Exclusion Criteria:

 -  patients less than 18 years of age

 -  patients undergoing transcranial surgery

 -  diagnosis other than that of pituitary adenoma on pre-operative MRI e.g., meningioma

 -  unable to provide consent e.g., mental illness or later withdrawing consent.