F-18 PET Bone Scans Versus Tc-99m Bone Scans for the Diagnosis of Bone Metastases
F-18 PET Bone Scans Versus Tc-99m Bone Scans for the Diagnosis of Bone Metastases
The purpose of this study is to compare 18F-Fluoride PET bone scans to traditional 99mTc-MDP
 bone scan to determine if one is better for diagnosing bone metastases.
Compare the diagnostic sensitivity, specificity, and accuracy of 18F-Fluoride PET bone scans
 versus traditional 99mTc-MDP bone scans for detecting bone metastases.

 Determine if there is a significant change in clinical management between the two types of
 scans.

 Measure and compare the number of equivocal or uncertain findings that would have caused
 additional testing, particularly additional imaging studies, to be performed for confirmation
 when using 18F-Fluoride PET bone scans versus 99mTc-MDP bone scans.

 To quantify any adverse events resulting from either scan.

 To perform subgroup analyses according to cancer cell type.
Inclusion Criteria:

 -  Patient has cancer

 -  Has been referred for evaluation of bone metastases

 -  Patient or patient's legal representative can understand and consent to enrollment in
 the study

 -  Must be 18 years or older

 -  Can remain still during the scan (approximately one hour)

 -  Patient has Medicare

 Exclusion Criteria:

 -  Patient does not have Medicare

 -  Under the age of 18

 -  Cannot lie still for the necessary time