Development of AECOPD Identification Tool (DETECT Study)
Development of AECOPD Identification Tool (DETECT Study)
This study is an observational, multi-center and cross sectional study,to develop an
 identification tool on purpose of differentiating COPD exacerbation from patients with
 respiratory symptoms in community hospitals of China.
This is an observational, multi-center and cross-sectional study to develop an AECOPD
 identification tool. Estimated totally 7 tertiary hospitals with experts in respiratory area
 will be involved as the study sites. These study sites will cover the regions of China
 (Eastern, Southern, Northern, Central, Western and Northeastern region), to be representative
 for the patient features all over the country. The patients will be enrolled in a
 "consecutive" way, which is, the investigators will recruit the patients who are eligible and
 consented to participate in this study without personal tendency.

 For the enrolled patients, a face to face visit between investigator and patient will be
 arranged. The evaluation for the symptoms and signs will be performed and the relevant data
 will be collected on the visit. In addition, other relevant tests (e.g. oxygen saturation,
 blood test, CAT, etc) and data (demographic, medical history, etc) will be collected on this
 visit.
Inclusion Criteria:

 -≥ 40 years old of age.

 -  Able to adequately understand written and verbal

 -  A signed and dated written informed consent must be obtained prior to the visits

 -  Patients see doctors due to suffering respiratory disease below:

 Disease type 1 - diagnosed moderate and severe stable COPD

 -  Patients with a diagnosis of COPD and documented record with predicted ratio of FEV1
 to forced vital capacity (FVC) < 0.70 before the study visit

 -  COPD with moderate to severe airflow obstruction (FEV1<0.8 predicted)

 Disease type 2 - AECOPD

 -  Patients with a diagnosis of COPD and documented record with predicted ratio of FEV1
 to forced vital capacity (FVC) < 0.70 before the study visit

 -  Patients consult the clinic or the emergency department because of acute worsening
 with an AECOPD (diagnosed by more than 2 clinical experts and refer to diagnosis
 criteria of Appendix 2)

 Disease type 3

 -Non-COPD patients with chronic respiratory symptoms such as cough, sputum and wheeze,
 dyspnea etc. (≥2 high risk factors )

 Exclusion Criteria:

 -  Patients with severe cardiovascular disease, including uncontrolled hypertension with
 drug treatment, unstable angina, myocardial infarction within the last 6 months, NYHA
 class II congestive heart failure, severe arrhythmia, pericardial effusion, etc.

 -  Patients with lung cancer, esophageal cancer or mediastinal tumors;

 -  Patients who participated in any drug clinical trials within 4 weeks before
 enrollment;

 -  Patients with severe infection, indicated for intravenous antibiotics, antifungal or
 antiviral therapy;

 -  Patients suffering from mental illness and poor compliance;

 -  Patients inappropriate for inclusion decided by investigator.