Micrometastasis in Gastrointestinal Cancer
Micrometastasis in Gastrointestinal Cancer
Prognostic and predictive value of assessing the patients micrometastasis status in blood and
 bone marrow when diagnosed GI cancer. 2 different patient subgroups are currently studied,
 patients with cancer of the pancreas and patients with liver metastasis secondary to
 colorectal cancer.

 Our hypothesis is that patients with detective circulating tumor cells in the blood or
 disseminated tumour cells in their bone marrow at diagnosis have a more advanced disease than
 negative patients. This information may be of therapeutic interest.
Oncological and overall outcome of the included patients are consecutively registrated at the
 out-patient clinic. At end of follow-up these survival data are analysed according to the
 presence of tumor cells in blood and bone marrow, and the prognostic impact of their presence
 are assessed.
Inclusion Criteria:

 1. Histological proven adenocarcinoma of the pancreas

 2. Histological/radiological verified colorectal liver metastases

 3. Consent capable patient

 4. Signed written, informed consent

 Exclusion Criteria:

 1. Patient'history of other malignancy