Efficacy and Safety Clinical Trial of the Combination of Acetylsalicylic Acid, Sodium Bicarbonate and Citric Acid, Produced by Geolab Pharmaceutical Industries Ltd., Compared to Acetylsalicylic Acid (Aspirin ® - Bayer) in Patients With Episodic Tension-type Headache.
Efficacy and Safety Clinical Trial of the Combination of Acetylsalicylic Acid, Sodium Bicarbonate and Citric Acid, Produced by Geolab Pharmaceutical Industries Ltd., Compared to Acetylsalicylic Acid (Aspirin ® - Bayer) in Patients With Episodic Tension-type Headache.
This study aims is to evaluate, two hours after a single administration, the rate of
 sustained response produced by the association Geolab consisting of acetylsalicylic acid,
 sodium bicarbonate and anhydrous citric acid - oral powder, with the active comparator
 acetylsalicylic acid (Aspirin ® -- Bayer) - a simple tablet for the treatment of acute pain
 in patients with mild to moderate CTTE, using for both the visual analog scale pain - VAS.
The secondary objectives of the study are to evaluate:

 -  Modification of gastric pH after administration of drugs by measuring with
 gastroesophageal pH Monitor, comparing the results between the groups;

 -  The incidence of administration of rescue medications, through the accounts of patients
 and researchers, comparing the results between the groups;

 -  The percentage of improvement in time 30, 60, 90 and 120 minutes after administration,
 using the visual analog scale (VAS), comparing the results between the groups;

 -  Evaluate the gastric symptoms before and after treatment by clinical investigation of
 patients, comparing the results between the groups;

 -  Evaluate the change in associated symptoms (photophobia, phonophobia, nausea, vomiting),
 using 4-point scale (0 - absent 1 - mild 2 - moderate 3 - severe), comparing the results
 between the groups;

 -  Assess the quantitative and qualitative parameters related to adverse reactions,
 comparing the results between the groups.
Inclusion Criteria:

 -  Agreed to participate in the study expressed by signing the two copies of the informed
 consent and informed consent (IC) after approved by the IRB;

 -  Minimum age of 18 years;

 -  Clinical history of TTH, according to the criteria of the International Classification
 of Headache of the International Headache Society, in face of crisis.

 Exclusion Criteria:

 -  Headache, migraine

 -  Chronic Tension-Type Headache (CTTH)

 -  Altered mental status

 -  Vital signs changed

 -  established or suspected pregnancy and lactation

 -  History of allergy to components of study drugs

 -  Current treatment with methotrexate

 -  Current treatment with Antinauseants

 -  Current treatment with anticoagulants such as heparin or coumarin-derivative

 -  gastric or duodenal disorders, chronic or recurrent active

 -  Liver and kidney disease severe

 -  Use of medications that have drug interactions with AAS