Hormonal Levels in Men With Major Depressive Disorder
Hormonal Levels in Men With Major Depressive Disorder
Subjects will be 1000 men meeting the following inclusion criteria: 1) male, age 18-65 years;
 2) meeting DSM-IV criteria for major depressive disorder within the past one year, with a
 HAM-D score >12.

 Subjects will be excluded if they exhibit 1) a substance abuse or dependence disorder within
 the past year; 2) current psychotic symptoms; or 3) a history of bipolar disorder.

 Procedure

 After informed consent, eligible patients will have blood drawn for serum hormone levels;
 cortisol, DHEA-S and testosterone or they will provide a salivary sample for measurement of
 hormone levels.

 We will also test hormone level form 1000 healthy males (from blood or saliva) at the same
 age for comparison.
Inclusion Criteria:

 -  Male

 -  Major Depression Disorder

 -  18-65