Factors Associated With Residual Disease In The Central Cone
Factors Associated With Residual Disease In The Central Cone
Cervical conization using the loop electrosurgical excision procedure (LEEP) is the standard
 treatment for patients with high-grade cervical intraepithelial neoplasia. Several studies
 have shown that excising a central cone reduces the rate of positive endocervical margins.
 The purpose of this study is to identify clinicopathological factors associated with residual
 disease in the central cone and to develop a predictive model to better determine which
 patients may require this additional procedure.
This study pretends to create a retrospective database including all patient who underwent a
 loop electrosurgical excision procedure by treatment for high-grade cervical intraepithelial
 neoplasia and create a a predictive model for top-hat resection in patients with high grade
 CIN
Inclusion Criteria:

 -  patients who underwent a loop electrosurgical excision procedure (LEEP)

 Exclusion Criteria:

 -  a diagnosis of micro-invasion or nonsquamous histology

 -  less than six months of follow-up

 -  incomplete information in their clinical charts.