The Glucosamine-study: The Effect of Glucosamine in Treatment of Chronic Low Back Pain
The Glucosamine-study: The Effect of Glucosamine in Treatment of Chronic Low Back Pain
Low back pain (LBP) is the most frequent cause of sick leave and disability pension, and
 degenerative and osteoarthritic (OA) changes is a significant cause of pain and disability.
 Some indications exist for symptomatic and possible cartilage-structurmodifying effect on
 knee- and hip-osteoarthritis with glucosamine sulphate (GS). The OA process in the lumbar
 spine is most likely to OA processes in knees and hips, hence GS could have comparable
 symptomatic and structural effect on lumbar OA.

 Study hypothesis: No difference in treatment effect exists between oral intake of GS- or
 placebo-capsules for patients' with chronic low back pain measured with Roland Morris
 Disability Questionnaire.
Inclusion Criteria:

 -  Low back pain for more than 6 months

 -  Patient older than 25 years old

 -  MRI findings comparable with lumbar degenerative/osteoarthritic changes.

 Exclusion Criteria:

 -  Spinal stenosis with neurological deficits

 -  Spinal prolapse with neurological deficits

 -  Rheumatoid arthritis, psoriatic arthritis,

 -  Old lumbar fractures

 -  Chronic pain syndromes (e.g. fibromyalgia)

 -  Psychosocial status not suitable for participation

 -  Pregnancy

 -  Breastfeeding

 -  Allergic to shellfish