tDCS for Multiple System Atrophy With Cerebellar Feature
tDCS for Multiple System Atrophy With Cerebellar Feature
The aim of study is to investigate most effective site for control the motor coordination
 using transcranial direct current stimulation in multiple system atrophy with cerebellar
 feature
Participants receive transcranial direct current stimulation (tDCS) over M1, cerebellar
 cortex or sham stimulation for 30 minutes. The type of stimulation depends on random
 assignment. The participants have a 1 week of wash out period between each stimulation.

 The assessment will be done by International Cooperative Ataxia Rating Scale (ICARS),
 GAITRITE (CIR Systems Inc., Clifton, New Jersey, USA) and PEDOSCAN (DIERS PEDO, Germany) at
 baseline and immediately after each treatment.
Inclusion Criteria:

 -  1. Patients who meet the clinical criteria for probable multiple system atrophy with
 cerebellar features (MDS second consensus statement on the diagnosis of multiple
 system atrophy)

 -  2. Patients aged between 40 and 70

 -  3. Patients who do not have rigidity and bradykinesia

 -  4. Patients who have given voluntary consent after understanding the content of the
 clinical trial

 Exclusion Criteria:

 -  1. Patients with a serious cognitive disorder, behavioral disorder, or mental illness

 -  2. Patients have history of seizure, stroke, encephalitis, other degenerative
 neurological disease

 -  3. Patients with a serious medical disease

 -  Patients who concomitantly suffer from severe renal impairment, convulsions,
 stomach ulcers, moderate or more severe liver disease

 -  Patients with un-controlled high blood pressure or diabetes

 -  4. Patients who have taken another investigational products within 4 weeks prior to
 being enrolled in this clinical trial, or patients who are pregnant or breastfeeding