Safety and Efficacy of Tazarotene Cream 0.1% Compared With Adapalene Gel 0.3% in the Treatment of Moderate to Severe Facial Acne Vulgaris
Safety and Efficacy of Tazarotene Cream 0.1% Compared With Adapalene Gel 0.3% in the Treatment of Moderate to Severe Facial Acne Vulgaris
Comparison of the safety and efficacy of Tazarotene Cream 0.1% compared with Adapalene Gel
 0.3% in treating moderate to severe facial acne vulgaris
Inclusion Criteria:

 -  Facial acne vulgaris characterized by the following: 25-100 facial inflammatory
 lesions (papules plus pustules); and 40 or more non-inflammatory lesions (open/closed
 comedones)); stable disease, non-rapidly regressing facial acne vulgaris; and, 3 or
 less facial nodules and/or cysts (diameter of 1cm or greater).

 -  Female subjects of childbearing potential must have a negative urine pregnancy test at
 baseline and practice reliable method of contraception throughout the study.

 Exclusion Criteria:

 -  Non-compliance with washout period

 -  Skin disease/disorder that might interfere with diagnosis or evaluation of acne
 vulgaris

 -  Allergy or sensitivity to any component of the test medications

 -  Cosmetic or surgical procedure complementary to the treatment of facial acne within 14
 days of the baseline visit