China Inherited Ventricular Arrhythmias Registry
China Inherited Ventricular Arrhythmias Registry
This is an observational, prospective, multi-center registry, aiming at building a risk
 stratification for malignant inherited ventricular arrhythmias, including Brugada
 syndrome(Brs)、Long QT syndrome(LQTS)、Short QT syndrome(SQTS)、Early repolarization
 syndrome(ERS) and Catecholaminergic polymorphic ventricular tachycardia(CPVT). 500
 participants will be recruited from 10 centers in China, with clinical data to be abstracted
 from medical records, and blood samples to be collected for finding related genes and
 promising risk indicators. The follow-up should be made every 6 months.
In China, the prevalence and risk factors of malignant ventricular arrhythmias remain
 unclear. In addition, mainstream treatment relies on implantable devices and medication.
 China Malignant Ventricular Arrhythmias Study is a nation-wide complex consisting of several
 interrelated studies, with the aim of building a risk stratification as well as an efficient
 and economic strategy for early prevention and treatment.

 Inherited Ventricular Arrhythmias Registry, as a part of China Malignant Ventricular
 Arrhythmias Study, is an observational, prospective, multi-center registry, aiming at
 exploring the correlation between genotype and phenotype for inherited structural ventricular
 arrhythmias, thus helping molecular diagnosis and risk stratification of these conditions.
 500 patients with definitive diagnosis will be recruited consecutively from 10 major
 arrhythmia centers distributed in 6 areas in China. At study entry, participants will be
 interviewed and asked to sign the informed consent. Demographic characteristics, medical
 history, clinical features, laboratory tests, imaging pictures, medications, procedures, and
 in-hospital outcomes of patients will be abstracted from medical records by well-trained
 staffs. At the same time, blood samples will be collected to detect biological markers, like
 genes, inflammatory factors ,etc. Once enrolled, the participants will receive follow up
 every 6 mouths about condition of arrhythmia, medication, clinical events, etc.
Inclusion Criteria:

 -  diagnosed as Brugada syndrome(Brs)、Long QT syndrome(LQTS)、Short QT
 syndrome(SQTS)、Early repolarization syndrome(ERS) or Catecholaminergic polymorphic
 ventricular tachycardia(CPVT).

 Exclusion Criteria:

 -  patients were enrolled by other clinical trials.