Tokushima Night Guard for Recurrent Aphthous Stomatitis
Tokushima Night Guard for Recurrent Aphthous Stomatitis
The investigators will investigate whether the night guard can suppress the development of
 recurrent aphthous stomatitis (RAS). The investigators will record the patients' oral
 condition for 60 days before and after intervention with the night guard made of
 Ethylene-Vinyl Acetate copolymer (EVA). The patients' saliva will be analyzed for measurement
 of inflammatory cytokines or oxidative stress.
The study involved 20 patients (8 male and 12 female) with RAS. These patients suffered from
 RAS at least once a month. The investigators will record their oral condition for 60 days
 before and after intervention with the night guard made of EVA. Their saliva will be analyzed
 for further studies including measurement of inflammatory cytokines or oxidative stress.
Inclusion Criteria:

 -  Patients suffered from recurrent aphthous stomatitis at least once a month

 Exclusion Criteria:

 -  People do not have a experience of recurrent aphthous stomatitis