Green Light Therapy As a Non-Pharmacologic Intervention to Decrease Anxiety in Pregnant Women With Opioid Use Disorder
Green Light Therapy As a Non-Pharmacologic Intervention to Decrease Anxiety in Pregnant Women With Opioid Use Disorder
This is a clinical trial evaluating anxiety reduction for women with opioid use disorder
 affecting pregnancy. It is well documented that anxiety increases as pregnancy progresses. We
 hypothesize that women who undergo green light therapy (experimental arm) will have a smaller
 increase in anxiety scores compared to the women who undergo white light therapy (control
 arm).

 We will also look at how much opiate replacement therapy increases women require during the
 study period, and how much opiate they require during admission for delivery. We think this a
 is a low risk intervention in a pregnant population that has higher levels of anxiety when
 compared to the general population. We believe based on animal studies that this could be
 effective, and change the way we treat and support individuals with substance use disorder.

 The opioid epidemic has negatively impacted our society at many levels. Finding
 non-pharmacologic ways to support patients while in recovery/sustained sobriety that are
 simple and low cost would be a step forward in providing compassionate and comprehensive
 treatment to individuals affected by Opioid Use Disorder.
At time of enrollment, participants will be administered a States-Traits Anxiety Inventory
 (STAI) questionnaire, undergo screening for ACE score (adverse childhood experiences), and
 will be asked about basic demographic data. After they complete the initial surveys, the
 patient will be assigned to either the control group or the experimental group. They will be
 sent home with the light, along with instructions to use their light every night for 1-2
 hours as ambient lighting. We hope to enroll a maximum of 26 patients in this study with 1:1
 randomization (13 control, 13 experiment).

 At approximately halfway through the intervention, the PI will call the patient and ask how
 often she has been using the light, how long she uses the light for every night, and whether
 she has noticed any effects (either positive or negative).

 At the prenatal visit around 36 weeks gestation or at time of delivery, whichever is sooner,
 patients will be asked by the PI to turn in their light and also fill out the STAI once
 again.

 After delivery, the PI will review the medical record and record any change in opioid
 replacement therapy during pregnancy as well as the total dose of opiate required during the
 inpatient admission for delivery.

 We hope to enroll a maximum of 26 patients in this study with 1:1 randomization (13 control,
 13 experiment)
Inclusion Criteria:

 Pregnant women between 20 - 32 weeks gestation with a diagnosis of opiate use disorder
 receiving care through Banner University Medical Center North Mothers Over Medicine (MOMs)
 Clinic, a high-risk pregnancy clinic for women with substance use disorder complicating
 pregnancy

 Exclusion Criteria:

 1. Inability to speak or understand English

 2. Incarcerated individuals

 3. Age <18 yo