Management for Concomitant Gallstones and Common Bile Duct Stones.
Management for Concomitant Gallstones and Common Bile Duct Stones.
Choledocholithiasis is identified in approximately 3-10 % of patients with cholelithiasis.
 (1-3) While laparoscopic cholecystectomy (LC) is considered the treatment of choice in
 patients with gall bladder stones, there is a debate about the management of common bile duct
 (CBD) stones, (4) and this has led to a range of therapeutic strategies for the management of
 concomitant gallstones and CBD stones patients. Two-stage endoscopic management using
 endoscopic retrograde cholangiopancreatography (ERCP) followed by laparoscopic
 cholecystectomy is a common approach, although single-stage management by laparoscopic
 cholecystectomy with surgical exploration of the CBD is an alternative, with the single-stage
 approach more common in the open surgery era. Currently, it is unclear whether two-stage
 management is better than or at least equivalent to the single-stage surgical approach to
 choledocholithiasis. To address this, we undertook this study to compare these two
 approaches. The aim of this prospective randomized trial was to determine the best technique
 for the management of patients with concomitant gallstones and common bile duct stones, by
 comparing the success rate, complication rates, and longer-term follow-up outcomes.
Single stage approach Under General anaesthesia a5 trocar method will be used to access the
 abdominal cavity. Aconventional approach to laparoscopic cholecystectomy will be first
 udertaken with dissection of calot's triangle. The cystic duct will be pulled laterally to
 facilitate exposure of the anterior wall of the CBDand the CBD will be opened longitudinally
 for adistance of approximately 1to1.5 cm using laparoscopic scissors. A5mm flexible
 choledoscope will be used to identify the CBD stone(s) which will be removed by flushing
 sterile saline, passingastone basket, or electrohydraulic lithotrpsy as necessary to clear
 the CBD. A T-tube will be inserted into the CBD via the choledochotomy which will be closed
 by interrupted resorbable sutures, before completing the cholecystectomy. Cholangiography
 throuh T-tube be performed 14 14 days later and the T-tube will be removed immediately after
 Cholangiography if no residual CBD stones is identified. If residual stones are found then
 will be removed through the T-tube track using A choledoscope Two-stage approach The
 treatment process commenced with intial endoscopic treatment phase. This will be udertaken
 Under General anaesthesia and entailed ERCP and endoscopic sphincterectomy. The CBD stones
 will be removed using a basket or ballon, with lithotrpsy added if necessary. An endoscopic
 nasobiliary drainge will be inserted and kept in place until after laparoscopic
 cholecystectomy which perfermed 2 to 5 days later depending on the patients 's condition..
 Surgery will be delsyed if urine amylase is elevated or significant abdominal pain is
 present. 2 to 5 days after the operation, Cholangiography will be performed via endoscopic
 nasobiliary drainge tube. And the endoscopic nasobiliary drainge tube wii be removed if no
 residual CBD stones are seen.
Inclusion Criteria:

 Age 16 to 70 years; Clinical presentation with biliary colic with or without jaundice;
 Serum elevation of at least one of the following enzymes: aspartate aminotransferase,
 alanine aminotransferase, glutamyl transpeptidase, alkaline phosphatase, and total
 bilirubin; Radiological findings suggestive of gallstones and concomitant common bile duct
 stones, with abdominal ultrasound showing possible CBD stones or a dilated CBD >8 mm in
 diameter.

 only patients with MRCP evidence of a CBD stone(s) were eligible after meeting all the
 previous criteria.

 Exclusion Criteria:

 active acute pancreatitis, pregnancy, septic shock, intrahepatic gallstones, malignant
 pancreatic or biliary tumors, prior sphincterotomy, unfit for anesthesia and surgery,
 contraindications to MRCP and ERCP, liver cirrhosis, previous history of abdominal surgery
 (e.g., gastrectomy), and inability to give informed consent.