Influence of U-relax on Vaginal Health Promotion and HPV DNA Test Change From Positive to Negative
Influence of U-relax on Vaginal Health Promotion and HPV DNA Test Change From Positive to Negative
The purpose of this study is to understand the effect of using oral U-relax on HPV infected
 women for vaginal environment health promotion, and the HPV DNA Test Index change from
 positive to negative. Long-term infection of HPV is associated with cervical cancer. U-relax
 contains Lactobacillus GR-1 and Lactobacillus RC-14 and has been approved of its benefits on
 treatment of BV, UTI, IBD and can improve vaginal environment health. Patients with positive
 result of HPV DNA test have no appropriate and aggressive treatment to reduce the risk of
 cervical cancer. This clinical trial tries to reveal the influence of oral U-relax and
 patients with HPV DNA test positive result.
This study is a prospective, double blind, randomized clinical trial. Vaginal health
 screening and HPV DNA Test are carried out from 80 patients with positive HPV DNA Test after
 conization for 6 months. All these patients will participant this study during the 360-day
 trial period. All health related conditions will be monitored at the same time.
Inclusion Criteria:

 -  female

 -  age over 30

 -  PAP Test with NEGATIVE FOR INTRAEPITHELIAL LESION OR MALIGNANCY result

 -  HPV DNA Index Test with POSITIVE result after conization for 6 months

 -  not pregnant

 Exclusion Criteria:

 -  cervical intraepithelial neoplasia before conization

 -  cervical cancer patient

 -  with GI surgery

 -  GI dysfunction

 -  need for long-term antibiotics treatment