Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion
Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion
The effects colchicine administration for acute pericardial effusion after radiofrequency
 catheter ablation (RFCA) of atrial fibrillation on the recurrences of arrhythmia.
RFCA was started as a rhythm control of atrial fibrillation about 10 years before and the
 superiority of RFCA to medical treatment has been continuously reporting, so RFCA is globally
 performed nowadays. Acute pericardial effusion could occur during RFCA as complication, that
 might be developed to cardiac tamponade needed immediate pericardiocentesis. The inflammation
 developed after pericardiocentesis might be associated with the recurrences of atrial
 fibrillation, it could be presumed by the frequent occurrence of atrial fibrillation after
 open-heart surgery. The inflammation can be suppressed by administration of colchicine and
 the effects of colchicine have been proven to decrease the development of atrial
 fibrillation.
Inclusion Criteria:

 -  Patients needed to pericardiocentesis during RFCA for paroxysmal or persistent atrial
 fibrillation.

 Exclusion Criteria:

 -  Hypersensitivity on Colchicine

 -  The existence of intra-cardiac thrombus on trans-esophageal echocardiography

 -  Pregnancy