Metoclopramide for Post Traumatic Headache
Metoclopramide for Post Traumatic Headache
Nearly 1.5 million patients present to US emergency departments annually following head
 trauma. Headache is a frequent symptom of victims of head trauma. The purpose of this study
 is to see if an intravenous medication called metoclopramide can improve the symptoms of
 patients with acute post-traumatic headache.
Inclusion Criteria:

 Included patients will be adults who meet International Classification of Headache
 Disorders criteria for acute post-traumatic headache. These are as follows:

 -  Traumatic injury to the head has occurred

 -  Headache has developed within 7 days of injury to the head

 -  Headache is not better accounted for by another diagnosis (eg, previous history of
 migraine or tension-type headache)

 The headache must be rated as moderate or severe in intensity at the time of initial
 evaluation.

 Exclusion Criteria:

 Patients will be excluded if more than ten days have elapsed since the head trauma, if the
 headache has already been treated with an anti-dopaminergic medication, or for medication
 contra-indications including pheochromocytoma, seizure disorder, Parkinson's disease, use
 of MAO inhibitors, and use of anti-rejection transplant medications.