Diagnosing of Acute Tuberculosis
Diagnosing of Acute Tuberculosis
Sweat proteins are analysed to investigate differences in protein markers in patients with
 acute tuberculosis and other pulmonary diseases (pneumonia, Bronchitis, chronic obstructive
 pulmonary disease (COPD)) and healthy individuals. Differences in sweat protein markers in
 patients with positive and negative tuberculosis Enzyme-linked-immuno-Spot (EliSpot) are
 investigated.

 Differences in sweat protein markers in the course of treatment in patients receiving
 tuberculostatic therapy are investigated.
Inclusion Criteria:

 -  Adult patients

 -  Ability to understand the purpose of the study, provide signed and dated informed
 consent by patient or his/her legal representative

 -  In-patients with acute tuberculosis, suspected tuberculosis or other pulmonary
 diseases (pneumonia, Bronchitis, COPD)

 Inclusion Criteria Healthy Donors:

 -  negative for Quantiferon- TB Gold Plus Test or ELISpot

 Exclusion Criteria:

 -  Initiation of tuberculostatic therapy before baseline

 -  Initiation of antibiotic therapy in patients with other pulmonary diseases > 6 hours
 before baseline