Evaluation of Therapeutic Efficacy in Use of Chamomilla Gel, Chamomilla Infuse and Urea in Radiodermatitis
Evaluation of Therapeutic Efficacy in Use of Chamomilla Gel, Chamomilla Infuse and Urea in Radiodermatitis
This study aims to evaluate therapeutics interventions in radiodermatitis in patients with
 breast or head and neck cancer. The data collect is going to begin after determining the
 better dose in a dose-response curve that is being conduct now in the same institution. To
 evaluate the skin reaction will be applied scale of the Radiation Therapy Oncology Group
 (RTOG) - Acute Radiation Morbidity Scoring Criteria, Common Terminology Criteria for Adverse
 Events (CTCAE) and Radiation-Induced Skin Reaction Assessment Scale (RISRAS).
Hypothesis:

 Chamomila gel is more effective than urea (usual care); Chamomila infuse is more effective
 than urea (usual care); Chamomila gel is more effective than chamomila infuse; Chamomila
 infuse is more effective than chamomila gel; Chamomila gel is as effective than urea (usual
 care); Chamomila infuse is as effective than urea (usual care); Chamomila gel is as effective
 than chamomila infuse; Chamomila infuse is as effective than chamomila gel.
Inclusion Criteria:

 Being an adult, over the age of 18 years old; Owning diagnosis of breast or head and neck
 cancer; Being first referred to the radiotherapy protocol; Presenting radiodermatitis
 grades 1 or 2, second RTOG score, in the place where is receiving radiation therapy; No
 history of previous hypersensitivity reaction to chamomile or any plant of the Asteraceae
 or Compositae family or Urea; Demonstrate understanding to continue the intervention in
 their home environment when necessary.

 Exclusion Criteria:

 Medical prescription, during the process of data collection, some kind of intervention to
 prevent radiodermatitis