Anti-mullerian Hormone Levels in Healthy Females
Anti-mullerian Hormone Levels in Healthy Females
The purpose of this study is to have a better understanding of the normal blood levels of AMH
 in females from 0-18 years of age and how the blood AMH levels correspond to a female's
 reproductive development.
Anti-mullerian hormone (AMH) is a chemical in the body that is found in the blood that can
 estimate the ability of a female to have her own children. It is widely used in adult female
 cancer patients to predict the onset of menopause and/or the inability to have children that
 can be associated with chemotherapy and/or radiation treatment. Normal blood levels of AMH
 are better understood in adults than in children and adolescents. The purpose of this study
 is to have a better understanding of the normal blood levels of AMH in females from 0-18
 years of age and how the blood AMH levels correspond to a female's reproductive development.
 With a better understanding of normal AMH levels in children, we may be able to better assess
 a girl's risk of not being able to have children if she is a cancer patient, and may be able
 to offer her and her family options to increase the chances of having her own children.
Inclusion Criteria:

 1. Pre- and post-pubertal females

 2. Ages 0-18 years old

 3. Tanner Stage I- V

 4. Undergoing routine outpatient surgical procedure

 1. Hernia repair (inguinal, umbilical, epigastric)

 2. Excision of benign mass

 3. laparoscopic cholecystectomy

 Exclusion Criteria:

 1. Previous diagnosis of an illness associated with premature ovarian failure (Turner's
 syndrome, Fragile X permutation carrier) or endocrine disorder associated with
 irregular menstrual cycles (Cushing's disease, poorly-controlled Thyroid disease,
 hyperprolactinemia, polycystic ovary syndrome, and congenital adrenal hyperplasia) or
 insulin-dependent diabetes mellitus or autoimmune disorders

 2. Previous diagnosis of any malignancy or any history of systemic/local chemotherapy,
 radiation therapy, or stem-cell transplant.

 3. Previous surgical excision of one ovary or both ovaries

 4. Pregnant females

 5. All inpatient surgical patients

 6. Undergoing non-routine outpatient surgical procedures

 1. Central venous catheter placement

 2. Supprelin insertion/removal

 3. Breast mass excision

 4. Gastrostomy tube insertion