A Pumpkin Seed, Isoflavonoid and Cranberry Mix in LUTS/BPH
A Pumpkin Seed, Isoflavonoid and Cranberry Mix in LUTS/BPH
The aim is to assess the efficacy of a mix of Pumpkin Seed Extract, Soy Germ Isoflavonoids
 and Cranberry (Novex®) in the management of mild to moderate LUTS in BPH patients. The
 patients will be evaluated based on the severity of LUTS, urological quality of life, and
 erectile function.
This is a single-arm prospective open-label trial investigating a combination of pumpkin
 seed, isoflavonoid and cranberry mix in improving LUTS, urological quality of life, and
 erectile function in BPH patients. The compound will be administered orally two tablets daily
 for 3 months. Recruited patients will be seen at 3 visits: initial visit (visit 1), 1-month
 visit (visit 2) and 3-month visit (visit 3) and their data will be collected in a dedicated
 case report form.
Inclusion Criteria:

 -  mild to moderate LUTS due to BPH for at least 6 months at the initial visit

 -  no previous therapy or are still symptomatic despite the current use of alpha-blockers

 Exclusion Criteria:

 -  International Prostate Symptom Score (IPSS) > 19

 -  Prostate cancer

 -  Urethral stenosis