Observational Study of Dydrogesterone in Cycle Regularization
Observational Study of Dydrogesterone in Cycle Regularization
Dydrogesterone has been widely used worldwide for various gynecological and obstetric
 indications:

 -  Dydrogesterone is effective in cycle regulation treatment.

 -  Dydrogesterone is recognized as none interference to hypothalamus pituitary ovary (HPO)
 axis in the recommended dosage.

 -  Dydrogesterone might have non-negative effect on glucose and lipid metabolic.
The current study is designed as a prospective, non-interventional, observational study.
 Patients with irregular cycle diagnosed as AUB-O will be prescribed dydrogesterone as per
 physician's clinical practice.
Inclusion Criteria:

 -  Women aged 16 years or above with menses

 -  Patient who is suffering from irregular menstrual cycle for at least 3 months and has
 been diagnosed as AUB-O (irregular cycle is defined as cycle duration < 21days or >35
 days)

 -  Physicians have decided to prescribe dydrogesterone 10mg for cycle regulation
 treatment, orally taking dydrogesterone 10mg twice daily, from day16 to day 25 of each
 cycle, being consecutive at least 3 cycles

 -  Patient who is willing to sign written authorization

 Exclusion Criteria:

 -  Hyperprolactinemia and thyroid dysfunction.

 -  Patient took cycle regulation treatment including oral contraceptives, sex hormone or
 glucocorticoid in the past 1 month

 -  Women with estrogen deficiency related symptom

 -  Patient who meets the contraindications listed in Chinese label of dydrogesterone

 -  Pregnant and lactating patients

 -  Patient who is not suitable for the study according to physician's discretion