Effect of Dexmedetomidine on Bispectral Index and Propofol Requirements During Different Menstrual Cycle
Effect of Dexmedetomidine on Bispectral Index and Propofol Requirements During Different Menstrual Cycle
The study was done to evaluate the effects of the follicular and luteal phases of the
 menstrual cycle on sedation level at loss of consciousness and bispectral index reach to 50
 during propofol anesthesia, in patients with and without preoperative intravenous
 dexmedetomidine .
Inclusion Criteria:

 -  a regular menstrual cycle

 -  elective gynecologic surgery

 Exclusion Criteria:

 -  pregnancy

 -  breastfeeding

 -  obesity

 -  known hypersensitivity to drugs used in the study protocol;

 -  use of psychotropic drugs and steroids within 72 hours before the surgery

 -  central nervous system injury

 -  renal impairment

 -  alcoholism and opioid addiction.