The Correlation Between Oxidative Stress and Indinated Contrast-Media Nephrotoxicity
The Correlation Between Oxidative Stress and Indinated Contrast-Media Nephrotoxicity
Clinically, iodinated contrast-medium (CM) is widely used in angiography and computerized
 tomography. CM-induced nephropathy (CMIN) is one major complication after application of CM.
 Therefore, how to prevent CMIN is always one of the hot topics concerned by nephrologists,
 cardiologists, and radiologists.

 The present study is aimed to determine the norepinephrine concentration, oxidative markers,
 and tubular damage markers in the urine samples of patients undergoing intravenous
 pyelography (IVP).

 The working hypothesis is high-osmolarity contrast media (HOCM) causes more oxidative stress
 and greater tubular damage than iso-osmolarity contrast media (IOCM).
Inclusion Criteria:

 1. Adult patients (> 18 years old)

 2. Undergoing IVP with an appropriate medical indication

 3. Signing informed consent

 Exclusion Criteria:

 1. Without signing informed consent