An EHR-based Platform To Facilitate Outcomes and Research Methods in Cerebrovascular Diseases
An EHR-based Platform To Facilitate Outcomes and Research Methods in Cerebrovascular Diseases
In this protocol, the investigators present methods and preliminary results from the
 PLATFORM-CVD Study, an EHR-based multicenter cohort. This study will focus on assessing the
 distribution of major cerebrovascular diseases, determining the risk factors associated with
 disease incidence and worse in-hospital outcomes, as well as describing the quality of care.
 Data from this cohort will be used to develop suitable prediction models for cerebrovascular
 diseases using real-world data and to understand how outcomes for cerebrovascular diseases
 would change with quality improvement interventions.
Adherence to healthcare quality measures is needed to reduce the burden of cerebrovascular
 disease and improve clinical outcomes. Electronic health records (EHRs) can facilitate the
 standardization of care provision and the improvement of disease prediction and prevention.
 Although the EHRs in clinical settings are increasingly prevalent in China, they are rarely
 used for healthcare research. the investigators aimed to conduct an EHR-based registry study
 to improve the healthcare and outcomes for cerebrovascular diseases.

 Twenty-four hospitals were enrolled in the PLATFORM-CVD Study in January 2018. Data
 collection began on February 1st, 2019. Historical data from January 2017 are abstracted
 first and prospective data are continuously reported until May 20th, 2020. Data were
 abstracted from the medical records, including hospital information system, laboratory
 information management system, and picture archiving and communication systems by an
 extract-transform-load tool. The EHR system included diagnostic information for cerebral
 infarctions (I63), nontraumatic intracerebral hemorrhages (I61), nontraumatic subarachnoid
 hemorrhages (I60), transient cerebral ischemic attacks and related syndromes (G45),
 intracranial and intraspinal phlebitis and thrombophlebitis (G08), vascular dementia (F01),
 and other aneurysms (I72). The quality of stroke care was assessed by 21 evidence-based
 performance measures. In-hospital outcomes were calculated including mortality, length of
 stay, and costs.

 The PLATFORM-CVD Study leverages EHRs to better understand incident cerebrovascular diseases
 in China. Data from this cohort will serve as a unique platform for quality assessment and
 improvement for acute treatment and secondary prevention of cerebrovascular diseases, as well
 as in-hospital outcome risk predictions and health economic evaluations.
Inclusion Criteria:

 -  Patients were included in the registry if they were hospitalized with a primary
 diagnose of：

 -  cerebral infarction (I63)

 -  nontraumatic intracerebral hemorrhage (I61)

 -  nontraumatic subarachnoid hemorrhage (I60)

 -  transient cerebral ischemic attack and related syndromes (G45)

 -  intracranial and intraspinal phlebitis and thrombophlebitis (G08)

 -  vascular dementia (F01)

 -  other aneurysms (I72)

 Exclusion Criteria:

 -  Patients diagnosed with other diseases.