Serum Parameter Prior and After EUS-guided Fine Needle Aspiration of the Pancreas
Serum Parameter Prior and After EUS-guided Fine Needle Aspiration of the Pancreas
Endoscopic ultrasonography (EUS ) -guided fine needle aspiration (EUS -FNA ) of focal
 pancreatic lesions is an essential diagnostic procedure with high therapeutic effect in
 clinical routine.

 The aim of this study is to determine the levels of serum lipase, serum amylase and the tumor
 marker CA 19-9 prior and after EUS-FNA. In animal experiments on dogs, an increase of all
 three parameters was observed after surgery on the pancreas. For humans, these clinically
 important data are not yet available .

 It is assumed that the probability of pancreatitis with increased activity of lipase and
 amylase will rise with the number of puncture procedures as well as the size of the puncture
 needle. In addition, the post-interventional assessment of the tumor marker CA 19-9 could
 result in a false positive assumption of malignant neoplastic pancreatic lesion.
Inclusion Criteria:

 -  independent indication for pancreatic EUS-FNA

 -  age ≥ 18 years

 -  patient able to give informed consent

 Exclusion Criteria:

 -  Contraindications for EUS-FNA

 -  pregnancy

 -  no informed consent available

 -  known stenosis of esophagus or duodenum

 -  relevant coagulation disorders