Effects of Clobazam on Sleep and Daytime Function in Patients With Epilepsy
Effects of Clobazam on Sleep and Daytime Function in Patients With Epilepsy
The purpose of this study is to monitor the effect of Clobazam on sleep and daytime alertness
 in people with Epilepsy.
Many studies show that patients with epilepsy frequently have disrupted sleep, as well as a
 high level of daytime sleepiness. This may be due to a sleep disorder, nighttime seizures
 that lead to disrupted sleep, and other abnormalities. Sleep complaints are widely reported
 among patients with various epilepsy syndromes.

 Anti-seizure treatments may affect sleep. Effects vary by type of medication and other health
 issues. Generally, with improvement of seizure control, the sleep cycle improves and becomes
 more regular. However, some anti-seizure medications have been associated with insomnia.
 There have been studies that looked at sleep in relation to some anti-seizure medications.
 However, there are no currently available published reports on the effect of Clobazam (Onfi)
 on sleep.
Inclusion Criteria:

 -  adults aged 18 years or older

 -  diagnosis of epilepsy who are being considered for treatment with Clobazam

 Exclusion Criteria:

 -  known untreated moderate or severe sleep apnea

 -  major circadian rhythm disorders