Evaluation of a Novel Technique to Investigate CAS Piezo Electric Sensors
Evaluation of a Novel Technique to Investigate CAS Piezo Electric Sensors
The proposed study is evaluating a novel technology, Carotid Stenotic Scan (CSS), developed
 by the sponsor, CVR Global. Study Design. This is a prospective cohort study that will
 compare a new application of a technology, the CSS device, to reference standards for
 assessment of carotid disease.
The overall objectives of this study are to demonstrate that the Carotid Stenotic Scan (CSS)
 can accurately detect significant carotid artery stenosis.

 Secondary objective is to relate changes in CSS signal to different degrees of stenosis. We
 obtain a "proof of concept" if the device correlates strongly with the established
 classification of atherosclerotic carotid disease derived various imaging modalities
 including magnetic resonance angiography (MRA) and computer tomographic angiography (CTA),
 conventional angiography, or carotid ultrasound.
Inclusion Criteria:

 -  Subjects over 18 referred for carotid duplex ultrasound.

 -  Subjects over 18 referred for CT angiography, MR angiography, or conventional
 angiography of the carotid arteries

 Exclusion Criteria:

 -  Previous history of carotid endarterectomy, carotid artery stent

 -  Previous surgery involving the neck (including thyroidectomy or parathyroidectomy)

 -  Patients with prosthetic heart valve

 -  Patients unable to provide informed consent.