Rate of Duodenal-biliary Reflux Increases in Patients With Recurrent Common Bile Duct Stones
Rate of Duodenal-biliary Reflux Increases in Patients With Recurrent Common Bile Duct Stones
ERCP is the primary choice for removal of common bile duct stone (CBDS) currently. However,
 4-24% patients underwent recurrence after successful clearance of CBDS. Stone re-formation
 due to chronic inflammation of biliary duct is generally considered an important cause of
 CBDS recurrence, which is associated with duodenal-biliary reflux (DBR) after sphincterotomy.
 Although it was believed that DBR was the important cause of CBDS recurrence, the direct
 evidence was still lacking. Here we conducted a case control study to investigate the DBR
 rate in patients with recurrent CBDS after ERCP.
Inclusion Criteria:

 -  Patients with common bile duct stone underwent successful stone removal by ERCP in
 Xijing Hospital of Digestive Diseases.

 Exclusion Criteria:

 -  Gallbladder stones or hepatolithiasis;

 -  Stenosis of biliary duct;

 -  Incomplete common bile duct stone removal by ERCP;

 -  Common bile duct stent;

 -  Unable to provide informed consent.