Pilot Study of 18F-FLT PET
Pilot Study of 18F-FLT PET
Fractionated radiotherapy induces an observable change in the proliferative activity as
 assessed by pre-treatment and early-treatment 18F-FLT PET imaging. This study is designed to
 investigate 18F-FLT as a PET imaging agent for predicting treatment effectiveness in several
 tumors and will serve as a pilot study to a planned PO1 submission
Inclusion Criteria:

 -  Able to tolerate a PET/CT scan

 -  Age of 18 or older

 -  signed informed consent

 -  being considered for radiotherapy for treatment of CNS mets, Head and neck cancer,
 lung cancer, prostate cancer or esophageal cancer

 Exclusion Criteria:

 -  Prior XRT to site being studied

 -  severe claustrophobia or inability to tolerate PET/CT

 -  unable to provide written consent

 -  pregnant or breastfeeding women