DGB-01 Effects on Endurance Exercise
DGB-01 Effects on Endurance Exercise
The purpose of this research is to evaluate the effects of DGB-01 on performance of a 40-km
 time trial in trained male cyclists. The investigators believe that DGB-01 will improve
 performance on the time trial as measured by a reduction in the amount of time required to
 complete the distance, using a computerized cycle ergometer.
Inclusion Criteria:

 -  Healthy males who are trained cyclists with a maximal oxygen uptake relative to body
 weight equal to or greater than 45 ml O2/kg/min.

 -  Subjects must be in the competitive phase of their annual training cycle.

 -  Between ages of 18-60

 -  Availability- commitment of the subject/expected participation in the study for 97
 days.

 Exclusion Criteria:

 -  Specific allergy to milk proteins (this is different from lactose intolerance)

 -  Use of immunosuppressive medication in the case of organ transplants

 -  Planned surgeries.

 -  Kidney disorders

 -  Use of antihypertensive medications

 -  Cardiovascular disease

 -  Abnormal BUN, creatinine, hemoglobin, or hematocrit

 -  Body weight greater than 285 pounds

 -  A protein-restricted diet

 -  Subjects currently using dry whey protein supplements, N-acetylcysteine, or
 alpha-lipoic acid supplements. The wash-out period is 1 month for any of these
 supplements.

 -  All medications that can interfere with muscle mass such as corticosteroids (e.g.
 prednisone), testosterone replacement or anabolic drugs such as Megace