The Relationship Between Motor Cortex Oxygenation and Motor Function Recovery in Stroke Patients
The Relationship Between Motor Cortex Oxygenation and Motor Function Recovery in Stroke Patients
Stroke is the most common cause of motor function impairment. However, the functional
 impairment is not totally irreversible. Several mechanisms may involved in both the cortical
 and motor function recovery after onset of stroke, and most of them are related to changes of
 cortical perfusion and metabolism.

 Motor function recovery after stroke (especially middle cerebral artery territory lesion)
 frequently follow stereotypic pattern (brunnström stage).

 This study is designed to investigate the relationship between motor cortex
 oxygenation/metabolism and motor function recovery after stroke. To seek if there is similar
 stereotypic pattern of motor cortex oxygenation/metabolism change during the recover stage
 after stroke.
Participants receive evaluations (1/week for 3 months period) of

 -  motor function (Include: MMSE, brunnström stage, Fugl-Meyer Assessment of Physical
 Performance, Box and Block Test of Manual Dexterity, Functional Independence Measure)

 -  cortical perfusion detection during performing limb movements (using NIRS)

 Then use path analysis to investigate the relationship between motor cortex
 oxygenation/metabolism and motor function recovery after stroke.
Inclusion Criteria:

 -  Ischemic stroke(unilateral, onset within 7 days, without previous stroke history)

 -  Vital sign stable

 -  Upper extremity motor function impairment(brunnström stage I~III)

 Exclusion Criteria:

 -  with pacemakers

 -  Seizure history

 -  Serious dysrhythmias

 -  Poor cognition function(MMSE<13)