Wound Infiltration With Local Anesthetic Agent for Laparoscopic Appendectomy in Adult
Wound Infiltration With Local Anesthetic Agent for Laparoscopic Appendectomy in Adult
Acute appendicitis is one of the most common acute abdomens that need surgical intervention.
 Laparoscopic surgery much decreases postoperative pain of wound, however, pain remains an
 important determinant of recovery after surgery. Intraoperative local anesthetic agent
 infiltrated locally into surgical wound to relieve postoperative pain is a feasible and safe
 method suggested in some literature. However, there is no routine use of this method in
 clinical practice because its benefit is still unknown. Besides, very few evidence could be
 found in literature review. To date, there is still no double blinded, prospective,
 randomized control trial addressing in evaluation of its interest. In this study, the
 investigators aim at investigating the benefit of wound infiltration with local anesthetic
 agent (bupivacaine) for laparoscopic appendectomy in adult. The study design is a double
 blind, prospective, randomized control trial with a 1:1 allocation ratio. Fifty adult
 patients with appendicitis will be included. The control group undergo laparoscopic
 appendectomy without wound infiltration with local anesthetic agent, the intervention group
 undergo laparoscopic appendectomy with wound infiltration with local anesthetic agent
 intraoperatively. The clinical characteristics, outcomes, and patient's satisfaction will be
 recorded and analyzed. The investigators hope this study can provide a high level evidence in
 pain management of patient undergo laparoscopic surgery.
Including criteria:

 1. Clinical diagnosis of appendicitis and undergo laparoscopic appendectomy

 2. Age more than 20 years

 3. Well comprehensive in speaking Chinese

 Exclusion criteria:

 1. Age no more than 20 years

 2. Pregnancy

 3. Can not cooperate with evaluation

 4. Convert to open surgical method, resect more organs than appendix

 5. Using patient control analgesia

 6. Allergy to local anesthetic agent