A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Systolic Dysfunction
A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Systolic Dysfunction
The aim of this study is to assess whether increasing oral doses of Riociguat are safe and
 improve the well-being, symptoms and outcome in patients with pulmonary hypertension
 associated with left ventricular systolic dysfunction
Pharmacokinetics parameters were regarded as exploratory parameters. Adverse event data will
 be covered in Adverse events section.
Inclusion Criteria:

 -  Male and female patients with symptomatic pulmonary hypertension due to left
 ventricular systolic dysfunction despite optimized heart failure therapy

 Exclusion Criteria:

 -  Types of pulmonary hypertension other than group 2.1 of Dana Point Classification