HCG Versus Spontaneous LH in Intrauterine Insemination (IUI ) Cycles
HCG Versus Spontaneous LH in Intrauterine Insemination (IUI ) Cycles
We recently reported the superiority of the natural cycle to a natural cycle controlled by
 the administration of human chorionic gonadotropin (hCG) for planning the frozen-thawed
 embryo transfer cycles, demonstrating a probable negative impact of exogenous hCG on
 endometrial receptivity.Based on the above findings we conducted the first prospective study
 that assesses whether there is a difference in pregnancy rate after intrauterine insemination
 (IUI) in a natural cycle with spontaneous luteinizing hormone (LH) rise compared to natural
 cycles controlled by hCG for final ovulation.
Inclusion Criteria:

 -  age ≤ 36 years,

 -  regular menstrual cycles,

 -  body mass index (BMI) between 18 and 29 kg/m²,

 -  basal levels of FSH (≤ 12 IU/l),

 -  estradiol (≤ 80 pg/ml) and progesterone (≤ 1.6ng/ml) on day one of the cycle, normal
 hysterosalpingography (maximum 3 months prior starting the cycle).

 -  The use of donor sperm was also accepted as inclusion criteria.

 Exclusion Criteria:

 -  PCOS

 -  endometriosis