Rheos® Diastolic Heart Failure Trial
Rheos® Diastolic Heart Failure Trial
The CVRx® Rheos® Diastolic Heart Failure Trial is a prospective, randomized, double blind
 trial with up to 60 subjects conducted at up to five centers in Europe. All subjects will be
 followed up to one year post implant.
Inclusion Criteria:

 -  Be at least 21 years of age.

 -  Have bilateral carotid bifurcations that are below the level of the mandible.

 -  Have a left ventricular ejection fraction ≥ 45%.

 -  Clinical Heart Failure with elevated BNP or NT-Pro-BNP.

 Exclusion Criteria:

 -  History of or suspected baroreflex failure or autonomic neuropathy.

 -  History of symptomatic bradyarrhythmias, pericardial constriction, infiltrative
 cardiomyopathy, cardiac valvular disease.

 -  Organ or hematologic transplant.

 -  History of prior surgery, radiation, or stent placement in carotid sinus region.

 -  History of severe chronic kidney disease.

 -  Life expectancy to less than one year.