Genetic and Phenotypic Characteristics of Mitral Valve Prolapse
Genetic and Phenotypic Characteristics of Mitral Valve Prolapse
Phenotypic characterisation of MVP by echocardiography in families. Identification of genes
 involved in MVP.
After clinical identification of patients with MVP, doctors organize 1st degree relative
 familial screening. A comprehensive echocardiography was carried out along with clinical
 examination. All echo data were stored for off-line analysis by a sonographer in our
 Core-lab. Blood was sample at the time of echocardiography in adult patients for DNA
 analyses. Follow-up for mitral valve changes will be performed after 5 years.
Inclusion Criteria:

 -  Patients of any age

 -  with typical mitral valve prolapse

 -  relatives examined during familial screening

 Exclusion Criteria:

 -  Refusal of the patient