Analysis of a Beneficial Effect of Prolonges Topical Steroid Treatment After Low-risk Penetrating Keratoplasty
Analysis of a Beneficial Effect of Prolonges Topical Steroid Treatment After Low-risk Penetrating Keratoplasty
PURPOSE: To assess the impact of duration of topical steroid treatment on the incidence of
 endothelial graft rejection following normal-risk penetrating keratoplasty (PK). DESIGN:
 Prospective, institutional, longitudinal, randomized interventional trial including 406 eyes
 (age: 52 >= 19 years; follow-up: 42 >= 18months). METHODS: Postoperative treatment started
 with prednisolone acetate 1% eye drops five times daily and was tapered over the first 6
 months. Patients were then randomised into either short-term (stop topical steroid treatment)
 or long-term treatment (continue steroids once daily until 12 months).
PURPOSE: To assess the impact of duration of topical steroid treatment on the incidence of
 endothelial graft rejection following normal-risk penetrating keratoplasty (PK). DESIGN:
 Prospective, institutional, longitudinal, randomized interventional trial including 406 eyes
 (age: 52 >= 19 years; follow-up: 42 >= 18 months). METHODS: Postoperative treatment started
 with prednisolone acetate 1% eye drops five times daily and was tapered over the first 6
 months. Patients were then randomised into either short-term (stop topical steroid treatment)
 or long-term treatment (continue steroids once daily until 12 months). <=
Inclusion Criteria:

 -  Low risk keratoplasty

 Exclusion Criteria:

 -  High risk keratoplasty