HFNC Effect on BCSS in Patients With COPD
HFNC Effect on BCSS in Patients With COPD
The primary objective of this study is to look for a correlation between the use of high-flow
 nasal cannula in the outpatient setting in patients with previous chronic obstructive
 pulmonary disease exacerbation and the change in their Breathlessness, Cough, and Sputum
 Scale score. The hypothesis is that home use of high-flow nasal cannula will lead to a
 reduction in Breathlessness, Cough, and Sputum Scale score by 1.3.
This is a prospective pilot study. Targeted population include patients with chronic
 obstructive pulmonary disease , non-oxygen dependent, with a baseline normal bicarbonate on
 previous lab (within 6 months of enrollment). Patients will be randomly selected to be part
 of the study sample. Recruitment will occur in both inpatient and outpatient settings. An
 email briefly explaining the objectives of the study will be sent to Internal Medicine
 residents and Pulmonary Critical Care fellows to help in patients' recruitment. Patients will
 be enrolled in the study only after being seen by Dr. Abdo or Dr. Allen. The study is
 expected to finish by the end of January 2017 or twelve months post institutional review
 board approval. Patients will be recruited and enrolled over six months, and the collected
 data will be analyzed six months after the last patient was included in the study. The study
 will target a study sample of 30 as detailed in the statistical analysis section, where
 patients will be their own control (3 months without high-flow nasal cannula followed by 3
 months with high-flow nasal cannula).
Inclusion Criteria:

 One previous chronic obstructive pulmonary disease exacerbation in last year.

 Exclusion Criteria:

 Can not be oxygen dependant PaCO2 < 60