DEPORRA-CoProst: Assessment of New Fluorescence Imagery Techniques Using Prostate Chips From Transurethral Resections
DEPORRA-CoProst: Assessment of New Fluorescence Imagery Techniques Using Prostate Chips From Transurethral Resections
The aim of this study is divided in 4 different steps:

 -  the first step has two different purpose: assess the impact of the storage medium of
 fresh prostatic chips on fluorescence signal and adjust the entire chain
 (immunolabelling,counter-stain and imaging),

 -  the second step is the adaptation of immunolabelling protocol on histopathology slides,
 using fresh prostatic tissue,

 -  the third step is to validate the use of:

 1. the medical device created by the FEMTO-ST institute use for the detection of
 fluorescence signal on fresh tissue,

 2. the Light-CT scanner use for tissue structural observation.

 -  the four step is to check the preservation of morphological structure of tissue under
 the effect of laser excitation from the medical device.
Inclusion Criteria:

 -  Male patient over 18 years old.

 -  Patient scheduled for trans-urethral resection of prostate with:

 1. prostate specific antigen (PSA) blood level ≤ 4 ng/ml and age > 80 years old

 2. a suspected prostate cancer after a digital rectal examination (DRE) and a PSA
 blood level > 50 ng/ml or an existing prostate cancer

 -  Patient affiliated to social security or beneficiary of such a regime.

 Exclusion Criteria:

 -  Protected patient referred to in Articles L1121-6 to L1121-8 of the Code of Public
 Health