PTNS on Urinary and Global Quality of Life in MS Patients
PTNS on Urinary and Global Quality of Life in MS Patients
This is a single-centered, prospective, longitudinal, observational cohort study of patients
 with MS who suffer from lower urinary tract symptoms (LUTS) and are refractory to two prior
 treatment modalities who have elected to pursue PTNS therapy for LUTS.
Inclusion Criteria:

 -  Diagnosis of Multiple Sclerosis

 -  Lower urinary tract symptoms (urinary frequency, urgency and/or incontinence)

 -  Failed prior first and second line therapy (behavioral and pharmacotherapy)

 -  Electing for Posterior Tibial Nerve Stimulation therapy for urinary symptoms

 -  Patients performing Intermittent Catheterization are Eligible

 Exclusion Criteria:

 -  Indwelling catheters (urethral or suprapubic)

 -  Currently pregnant or planning pregnancy

 -  Unable to attend weekly office visits for PTNS

 -  Urodynamic findings of bladder outlet obstruction

 History of:

 bladder reconstruction (augmentation cystoplasty, catheterizable channel) cystectomy
 bladder stones pacemaker or defibrillator malignancy of bladder sacral neuromodulation
 intravesical injection of onabotulinum toxin within 9 months