Transcatheter Mitral Valvuloplasty Pilot Study
Transcatheter Mitral Valvuloplasty Pilot Study
This study is to evaluate the efficacy and safety of Transcatheter Mitral Valvuloplasty for
 Severe Mitral Regurgitation
Inclusion Criteria:

 -  Significant symptomatic mitral regurgitation (MR ≥ 3+) due to primary abnormality of
 the mitral apparatus [degenerative MR] in patients who have been determined to be at
 prohibitive risk for mitral valve surgery by a heart team, which includes a cardiac
 surgeon experienced in mitral valve surgery and a cardiologist experienced in mitral
 valve disease, and in whom existing comorbidities would not preclude the expected
 benefit from reduction of the mitral regurgitation.

 -  Age 19 and more

 -  Written informed consent

 Exclusion Criteria:

 -  Patients who cannot tolerate procedural anticoagulation or post-procedural
 antiplatelet regimen

 -  Active endocarditis of the mitral valve

 -  Rheumatic mitral valve disease

 -  Evidence of intracardiac, inferior vena cava (IVC) or femoral venous thrombus