Salivary C- Reactive Protein, Mean Platelet Volume and Neutrophil Lymphocyte Ratio as Diagnostic Markers for Neonatal Sepsis
Salivary C- Reactive Protein, Mean Platelet Volume and Neutrophil Lymphocyte Ratio as Diagnostic Markers for Neonatal Sepsis
To evaluate reliability of salivary C-reactive protein ,mean platelet volume , neutrophil
 -lymphocyte ratio , and platelet lymphocyte ratio in diagnosis of neonatal sepsis
Inclusion Criteria:

 -  - Full term neonates of both genders from birth to the 28th day of life diagnosed with
 sepsis by history, clinical findings, laboratory findings, and blood culture. The
 clinical findings included the presence of three or more of the following:

 -  (1) temperature instability (hypothermia, hyperthermia) .

 -  (2) respiratory alterations (grunting, intercostal retractions, apnea, tachypnea,
 cyanosis) .

 -  (3) cardiovascular alterations (bradycardia, tachycardia, poor perfusion, hypotension)
 .

 -  (4) neurologic alterations (hypotonia, lethargy, seizures)

 -  (5) gastrointestinal alterations (feeding intolerance, abdominal distension). CRP
 values >10 mg/L were considered to be positive.

 Exclusion Criteria:

 -  - Preterm neonates .

 -  Neonates with CNS malformations, metabolic disorders, chromosomal abnormalities,
 intrauterine growth restriction, or birth asphyxia were excluded from the study