Effect of Low Glycemic Index Diet on Body Composition and Mechanism of Obese Women
Effect of Low Glycemic Index Diet on Body Composition and Mechanism of Obese Women
Excessive body weight and obesity have reached epidemic proportions over the last few
 decades, which may cause many chronic diseases. Maintaining a healthy life style could
 decrease the risk for obesity, metabolic syndrome and cardiovascular disease. The study aimed
 to evaluate long-term low glycemic index (GI) diet intervention on lipid profile, body
 composition and the mechanism of obese women. The pilot study will recruit twenty healthy
 subjects, and served test food to determine low GI food. In the experiment period, twenty
 women age from 20-50 years will be recruited. To be included in the study, subjects should
 have a BMI above 24 kg/m2, or the either one (fat mass ≧ 30% or waistline > 80 cm). Before
 dietary intervention, participants will receive food choice table and dietary questionnaires
 to record their dietary intake.

 The study will be a randomized, crossover, controlled clinical trails. The experiment period
 have six weeks, each participants will provide low GI diet (lunch and dinner). On the 0, 3, 6
 week, subjects will measurement their body composition (body weight, body mass, waist and hip
 circumferences) and collect fasting blood samples to analysis the lipid profile, free fatty
 acid, blood sugar, insulin, adiponectin, leptin and fatty acid synthesis enzymes. Statistical
 analysis will be performed by paired t-test. The study expect that long-term low GI diet
 intervention have beneficial effects on regulate body composition of obese women.
Inclusion Criteria:

 -  BMI above 24 kg/m2, or the either one ( fat mass ≧ 30% or waistline > 80 cm )

 Exclusion Criteria:

 -  Cardiovascular disease

 -  type 2 diabetes mellitus or impaired glucose tolerance

 -  serious liver or renal disease, gastro-intestinal disease

 -  proceed serious diet control for formerly three months

 -  take any supplemental food products or medications known to influence lipid or
 carbohydrate metabolism