Carotid Atherosclerotic Disease Following Childhood Scalp Irradiation
Carotid Atherosclerotic Disease Following Childhood Scalp Irradiation
Background: During the first half of the 20th century, scalp irradiation was a standard
 treatment for induction of epilation in children suffering from Tinea Capitis. These children
 are now more than 50 years old and the aim was to investigate the possible association
 between their childhood low dose irradiation exposure and development of carotid
 atherosclerotic disease in adulthood.

 Methods: The study included 145 individuals treated by irradiation in their childhood, and
 150 matched control subjects with no history of irradiation. B-mode ultrasound imaging and US
 Doppler were used to measure carotid and femoral stenosis and Intima-Media Thickness (IMT).
 Blood samples were taken for lipid profile and homocysteine evaluation.
Inclusion Criteria:

 -  age 18 or older

 -  childhood scalp irradiation or mach controls

 -  writen informed consent

 Exclusion Criteria:

 -  inability to give written informed consent