Swiss Autoimmune Hepatitis Cohort Study
Swiss Autoimmune Hepatitis Cohort Study
Research project in which biological material is sampled and health-related personal data is
 further used and collected.

 Coded data are used.
To collect high quality prospective data on a rare disease in order to elucidate
 epidemiology, natural history, response to treatment and outcome. In addition, a biobank
 allows addressing specific scientific issues on a variety of open questions. The cohort will
 provide a platform for carrying out scientific research projects on AIH. In addition, the
 cohort will allow collaborations with reference networks on AIH abroad.

 Measurements and procedures: Enrolment visit and one follow-up visit at least once a year are
 planned. An additional follow-up visit at 6 months postdiagnosis is planned for newly
 diagnosed patients.

 Whole blood is collected for biobanking once a year Optionally, if available and collected
 during normal clinical procedures, liver fragments are obtained.

 Number of subjects projected for the entire study (all sites combined): 500 (corresponding to
 1/3 of the estimated global AIH population residing in Switzerland, assuming a disease
 prevalence of 20:100,000)
Inclusion Criteria:

 -  diagnosis of AIH, either type I or type II

 -  Only patients living in Switzerland

 Exclusion Criteria:

 -  N/A