Identification of Genetic Causes of Calcific Aortic Valve Disease
Identification of Genetic Causes of Calcific Aortic Valve Disease
This study aims to identify the molecular genetic causes of the variability in development of
 calcific aortic valve disease in bicuspid and tricuspid aortic valves and their associated
 aortic dilation.
Inclusion Criteria:

 -  Patients with a plan to undergo elective aortic valve replacement and/or ascending
 aortic surgery

 Exclusion Criteria:

 -  Age < 20 years

 -  Unable/unwilling to consent

 -  History of aortic valve replacement or transcatheter aortic valve replacement (TAVR)

 -  History of endocarditis

 -  History of rheumatic fever

 -  History of chest radiotherapy

 -  History of organ transplant