The Use of L-Carnitine And CoQ10 Supplements In the Treatment of Cyclic Vomiting Syndrome (CVS)
The Use of L-Carnitine And CoQ10 Supplements In the Treatment of Cyclic Vomiting Syndrome (CVS)
This is a study with the principle goal being to learn about the use of L-Carnitine and
 CoQ10, two vitamin supplements that are currently being used to treat Cyclic Vomiting
 Syndrome, largely initiated by parents. We want to learn how effective these supplements are
 compared to standard treatment, at what dose, and what onset of action in order to initiate
 future prospective study on these supplements.
Inclusion Criteria:

 -  3 discrete episodes of vomiting

 -  normal health between episodes

 -  stereotypical clinical pattern

 -  no abnormal test results to account for vomiting (see exclusion criteria)

 Exclusion Criteria:

 -  abnormal UGI with small bowel follow-through revealing an anatomic anomaly,
 inflammatory or obstructive

 -  Significantly abnormal endoscopic biopsies (moderate to severe esophagitis, H. pylori)

 -  Abnormal abdominal ultrasound revealing hydronephrosis, cholelithiasis, pancreatitis

 -  Positive screening for endocrine disorder (diabetic ketoacidosis, Addison's)

 -  Positive screening for inborn errors of metabolism (hypoglycemia, lactic acidosis,
 hyperammonemia, organic acidemia, amino aciduria, elevated beta-ALA, porphobilinogen)