The Changes of Body Fat Distribution in Obese Patients With PCOS After LSG
The Changes of Body Fat Distribution in Obese Patients With PCOS After LSG
Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with a prevalence of 5% to
 15% in premenopausal women. Patients with PCOS presents as abnormal menstruation, ovulation
 disorders and/or hyperandrogenemia, and often accompanied by insulin resistance and other
 metabolic abnormalities. Abdominal fat accumulation, overweightness and obesity are
 frequently present in patients with PCOS . Visceral adipose tissue (VAT) plays an important
 role in the pathogenesis of PCOS.Therefore，this study aim to investigate the changes of body
 fat distribution in obese women with PCOS after laparoscopic sleeve gastrectomy (LSG), and to
 explore the factors that may predict the changes in body fat distribution in PCOS patients
 after LSG.
Inclusion Criteria:

 1. Fmale aged 18- 45;

 2. Meet Rotterdam criteria(2003);

 3. body mass index (BMI)≥30 kg/m2

 Exclusion Criteria:

 1. Gender is male;

 2. Younger than 18 years old or older than 45 years old ;

 3. secondary obesity due to endocrine disorders;

 4. history of malignant tumors; 5）sever hepatic and renal disease;

 6) concurrent participation in other clinical trials; 7) sever endocrine and hereditary
 diseases; 8) mental illnesses that rendered them unable to provide informed consent; 9)
 patients declining to undergo complete study testing.