Immunological Memory Induced by the 13valent Pneumococcal Conjugate(PCV13) and 23valent Plain Polysaccharide Vaccine(PPV23) in HIV-infected Patients
Immunological Memory Induced by the 13valent Pneumococcal Conjugate(PCV13) and 23valent Plain Polysaccharide Vaccine(PPV23) in HIV-infected Patients
The purpose of this study is to determine the effect of a combined vaccination schedule of
 the 13-valent pneumococcal conjugate (PCV13) and 23valent plain polysaccharide vaccine
 (PPV23) on the establishment of immunological memory in HIV-infected adults on ART.
Inclusion Criteria:

 -  CD4 T cell count >200cells/μl

 -  on ART

 Exclusion Criteria:

 -  no previously recorded allergy to PCV, PPV23

 -  no intravenous immunoglobulin (IVIG) given within the previous 6 months

 -  no other vaccine given within the previous 6 months