The Effects of Multi-strain Probiotics in Adults With Diarrhea Predominant Irritable Bowel Syndrome
The Effects of Multi-strain Probiotics in Adults With Diarrhea Predominant Irritable Bowel Syndrome
The investigators will evaluate the efficacy of multi-strain probiotics in adults with
 diarrhea predominant irritable bowel syndrome.
Inclusion Criteria:

 -  willing to consent/undergo necessary procedures

 -  between the age of 19 and 75 years

 -  diarrhea predominant irritable bowel syndrome (satisfied with Rome II criteria)

 Exclusion Criteria:

 -  uncontrolled hypertension (Blood pressure > 180/110 mmHg)

 -  uncontrolled diabetes mellitus (FBS > 200 mg/dL)

 -  malignancy, cerebrovascular disease, cardiovascular disease

 -  history of abdominal surgery except appendectomy and hernia repair

 -  inflammatory bowel disease

 -  clinically or laboratory-confirmed gastroenteritis

 -  the use of motility drug or dietary fiber supplement in 2 weeks

 -  serum Cr > 2 x Upper normal limit

 -  AST or ALT > 2 x Upper normal limit

 -  Pregnancy, Lactating woman