Study Comparing Tigecycline to Imipenem/Cilastatin in Complicated Intra-Abdominal Infections in Hospitalized Subjects
Study Comparing Tigecycline to Imipenem/Cilastatin in Complicated Intra-Abdominal Infections in Hospitalized Subjects
Purpose: To provide a mechanism for the emergency use of tigecycline in the appropriate
 clinical situations.
Inclusion Criteria:

 -  Male or female subjects, ≥ 8 years of age and a weight of ≥ 35 kilograms

 -  Subjects with selected culture-positive infections caused by a multiple
 antibiotic-resistant pathogen presumed to be susceptible to tigecycline

 -  Subjects who have failed or are intolerant of other available appropriate antibiotic
 therapies or whose pathogens are resistant to other available antibiotics

 Exclusion Criteria:

 -  Subjects who are moribund with an expected survival of less than 2 weeks.

 -  Subjects who have been designated as "Do Not Resuscitate", unless it is anticipated
 within a reasonable degree of medical certainty that they can achieve benefit from
 potentially curative antibiotic therapy

 -  Known or suspected hypersensitivity to tigecycline, tetracyclines, or other compounds
 related to this class of antibacterial agents