Tranexamic Acid in Major Vascular Surgery
Tranexamic Acid in Major Vascular Surgery
The purpose of this study is to determine whether tranexamic acid is effective in reducing
 intraoperative blood loss and necessity for haemotransfusion in patients undergoing open
 abdominal aortic aneurysm repair
Inclusion Criteria:

 -  Age > 50

 -  Able to give written informed consent

 -  Undergoing open abdominal aortic aneurysm repair

 Exclusion Criteria:

 -  Patients participating in a pharmaceutical clinical trial in the last 3 months

 -  Urgent/emergent surgery

 -  Allergy/intolerance to tranexamic acid

 -  History of seizures

 -  Acute Venous or Arterial Thrombosis

 -  Fibrinolytic conditions due to consumption coagulopathy

 -  Disseminated intravascular coagulation

 -  Haematuria

 -  Visual disturbances