Prevention of Contrast-induced Nephropathy in Patients With Acute Myocardial Infarction
Prevention of Contrast-induced Nephropathy in Patients With Acute Myocardial Infarction
OBJECTIVE: To evaluate the efficacy of prevention of contrast induced nephropathy in patients
 with ST segment elevation myocardial infarction treated with primary percutaneous coronary
 intervention.

 DESIGN: Prospective study. SETTING: Three-center study Acute kidney injury was defined as a
 rise in creatinine >25% from baseline Serum creatinine will be measured at baseline and each
 day for the following 3 days and at 30 days.

 Patients will be randomised to:

 1. Standard treatment

 2. Standard treatment + acetylcystein for 2 days

 3. Standard treatment + Sodium bicarbonate 500 ml / followed by 100 ml/h for 5 hours

 4. Standard treatment + acetylcystein for 2 days + Sodium bicarbonate 500 ml / followed by
 100 ml/h for 5 hours
Inclusion Criteria:

 -  STEMI patients treated with primary PCI

 Exclusion Criteria:

 -  Cardiogenic shock