Evaluation of Oxidative Stress and Effect of Levothyroxine Treatment on Oxidative Stress in Hashimoto Disease
Evaluation of Oxidative Stress and Effect of Levothyroxine Treatment on Oxidative Stress in Hashimoto Disease
Oxidative stress leads to or accompanies with numerous disease. Oxidative balance in
 subclinical hypothyroid or euthyroid state in Hashimoto disease are not known. Effect of
 levothyroxine therapy on oxidative balance are also not known in hashimoto disease.
oxidative stress markers will be measured initially(TAS,TOS,OSI,PARAOXONASE,ARYLESTERASA,PON1
 PHENOTYPİNG,LİPİDPEROXİD).After 3 months therapy with levothyroxine measurements will be
 repeated except PON1 phenotyping.
Inclusion Criteria:

 -  age more than 18 years

 Exclusion Criteria:

 -  inability to give a written consent

 -  other conditions and drug usage affect oxidative stress