The Effect of a Weight Management Program During Treatment With Olanzapine
The Effect of a Weight Management Program During Treatment With Olanzapine
The study is a prospective, randomized, open-label study.
The principal objective of this trial is to investigate the effect of a comprehensive
 behavioural treatment program on weight gain in schizophrenic patients under olanzapine
 treatment, and on subjective well-being.
Inclusion Criteria:

 -  Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV)
 criteria for schizophrenia

 -  Ages between 18 and 65

 -  Informed consent

 -  Weight gain of at least 1.5 kg in the first 4 weeks

 -  A sufficient understanding to participate adequately in the weight management program

 -  Patients must agree to cooperate with all tests and examinations required by the
 protocol.

 -  Each patient must understand the nature of the study and must sign an informed consent
 document.

 Exclusion Criteria:

 -  Serious, unstable somatic illnesses

 -  Illnesses associated with weight gain including renal and endocrine diseases

 -  Weight change greater than 3 kg in the preceding three months

 -  Weight gain less than 1.5 kg in the first 4 weeks