Prospective Project to Identify Biomarkers of Morbidity and Mortality in Cardiovascular Interventional Patients
Prospective Project to Identify Biomarkers of Morbidity and Mortality in Cardiovascular Interventional Patients
The objective of CAREBANK study is to establish definitive relationships with human cardiac
 samples and clinical phenotypes in patients undergoing cardiac procedures. Specifically, the
 investigators aim at comparing atrial phenotypes from atrial fibrillation patients and
 controls. The work consists of three broad categories: A) role of atrial cardiomyopathy in
 atrial fibrillation; B) genetic defects predisposing to atrial fibrillation; and C) the role
 of inflammation in atrial fibrillation.
The investigators aim to A) compare atrial cardiomyopathy findings from the tissue samples to
 clinical phenotype and adverse events B) study the association of genetic defects
 predisposing to atrial fibrillation with atrial cardiomyopathy findings in the tissue samples
 C) assess the role of inflammation in atrial fibrillation by comparing circulating cytokine
 profiles, purinergic signaling and atrial cardiomyopathy findings in tissue samples.
Inclusion Criteria:

 -  Any open-heart cardiac surgery

 -  Written informed consent

 -  All-comers design

 Exclusion Criteria:

 -  No informed consent