Safety and Efficacy Study of Dual-axis Rotational Versus Standard Coronary Angiography
Safety and Efficacy Study of Dual-axis Rotational Versus Standard Coronary Angiography
The purpose of this study is to assess the clinical safety and efficacy of dual-axis
 rotational coronary angiography (DARCA) in the diagnosis of coronary artery disease by
 directly comparing it to standard coronary angiography (SA).
Dual-axis rotational coronary angiography (DARCA) was developed as an innovative adaptation
 of rotational angiography (RA), but it requires a longer coronary injection compared to
 standard coronary angiography (SA). The risk of complications from the contrast agent (such
 as discomfort, warmth, pain, hypotension and bradycardia) is increased with the use of DARCA.
 It remains to be evaluated whether this approach is also suitable for coronary angiography,
 especially using in the patients with complex coronary lesions. Previous studies revealed
 promising results, but the number of patients included did not provide sufficient statistical
 power to allow a valid comparison of DARCA with SA. The purpose of this study is to evaluate
 the feasibility, safety, clinical tolerance, and hemodynamic effect of DARCA in comparison to
 the well-established SA.
Inclusion Criteria:

 -  Age >18 years old

 -  A clinical indication for diagnostic coronary angiography to evaluate possible CAD

 Exclusion Criteria:

 -  Pregnancy

 -  Known allergy to iodinated contrast

 -  Renal insufficiency (>1.5mg/dL)

 -  Cardiogenic shock

 -  Acute myocardial infarction within one week

 -  Prior coronary artery bypass graft treatment

 -  Prior percutaneous coronary intervention treatment