Antibiotic Prophylaxis in Transurethral Prostate Resection (TURP) and Transurethral Bladder Tumour Resection (TURB)
Antibiotic Prophylaxis in Transurethral Prostate Resection (TURP) and Transurethral Bladder Tumour Resection (TURB)
To investigate the use of antibiotic prophylaxis in patients undergoing TURP and TURB. The
 investigators set up a prospective, randomized controlled trial in which (after exclusion of
 risk factors) patients will be randomized in receiving levofloxacin (Tavanic) orally or no
 antibiotics. The exclusion criteria for TURP are a pre-operative transurethral catheter or >
 100 urinary white blood cells in the pre-operative urine sample. The exclusion criteria for
 TURB are a pre-op catheter or clinical signs of infection.
Main objective:

 To investigate the safety of omitting antibiotic prophylaxis in TURP (transurethral resection
 of the prostate) and TURB (transurethral bladder tumour resection) in patients without a
 pre-operative catheter or > 100 WBC in the pre-operative urinary sample (TURP) or clinical
 signs of urinary infection (TURB).

 Secondary objective:

 To investigate post-operative bacteriuria after TURB and TURP in our population.

 Principal inclusion criterium:

 Patients undergoing TURP or TURB.

 Primary exclusion criterium:

 TURP: pre-operative catheter or > 100 white blood cells in the pre- operative urinary sample.

 TURB: pre-operative catheter or clinical signs of infection (fever, nyctalgia).

 Primary endpoint:

 Post-operative infection.

 Secondary endpoint:

 Post-operative bacteriuria.
Inclusion Criteria:

 -  TURP or TURB.

 Exclusion Criteria:

 -  TURP: pre-operative catheter/DJ/nephrostomy or > 100 white blood cells in the pre-
 operative urinary sample.

 TURB: pre-operative catheter/DJ/nephrostomy or clinical signs of infection (fever,
 myctalgia).