Low-voltage Areas Defragmentation in Sinus Rhythm for Radiofrequency Ablation of Persistent Atrial Fibrillation
Low-voltage Areas Defragmentation in Sinus Rhythm for Radiofrequency Ablation of Persistent Atrial Fibrillation
This is a study evaluating the value of defragmentation of sinus rhythmic low voltage areas
 in addition to isolation of pulmonary veins in the removal of recurrent atrial fibrillation.
 The invasive procedure will be performed according to the procedures chosen by the
 rhythmologist and will in no way be modified by the patient's enrollment in the study.
 Similarly, the frequency of consultations, date and nature of the additional examinations
 will be defined by the physician, with the purpose of monitoring the patient.
Radiofrequency ablation has become standard practice in the approach strategy for the
 symptomatic treatment of atrial fibrillation. The interest of substrate ablation, completing
 the isolation of the pulmonary veins is controversial. The usual technique for the ablation
 of recurrent atrial fibrillation is primarily a disconnection of the pulmonary veins, which
 can be accomplished by isolating the veins one by one or two by two. The isolation of the
 pulmonary veins is followed most often by a defragmentation of the atrium (ablation of the
 substrate). The defragmentation is guided by a map of fragmented potentials, made through a
 topography catheter, to locate the most abnormal areas that are the target of ablation. This
 strategy requires extensive ablation of the left atrium, with a long procedure time and
 repeated many radiofrequency shots. On the one hand there is a risk of complication related
 to the duration of intervention, but also in the longer term of occurrence of flutter scar.
 In addition to pulmonary vein isolation, the goal is to identify patients with sinus rhythm
 atrial arrhythmogenic substrate. Once the sinus rhythm has been restored by electrical
 cardioversion or spontaneously, a voltage map is carried out to identify the most abnormal
 (low voltage) areas, and intra-atrial fragmented potentials are identified, either
 spontaneously or spontaneously by the extra-stimulus method. Ablation of these abnormal areas
 may lead to better long-term results, limiting prolonged radiofrequency shots and
 complications associated with longer procedure times.
Inclusion Criteria:

 -  Patients with persistent atrial fibrillation ablation, no specific indication
 restrictions or equipment used and regardless of the outcome of the procedure

 -  Patients participating in a biomedical research can participate in this study.

 Exclusion Criteria:

 -  Pregnant or lactating women can not participate in this study