Prediction and Prevention of Asymptomatic Cardiovascular Insult in Type 1 Diabetic Children: Comparative Effectiveness of Cardioprotective Drugs
Prediction and Prevention of Asymptomatic Cardiovascular Insult in Type 1 Diabetic Children: Comparative Effectiveness of Cardioprotective Drugs
Diabetic cardiomyopathy (DCM) is a distinct clinical entity of diabetic heart muscle that
 describes diabetes associated changes in the structure and function of the myocardium in the
 absence of coronary artery disease, hypertension, and valvular disease. Oxidative stress
 plays a critical role in DCM development. DCM can be diagnosed using the novel methods of
 echocardiography (tissue Doppler imaging, Speckling tracking techniques and more recent real
 time 4D echocardiography). There is a possible cardioprotective effect of statins, Captopril
 and L-Carnitine in type 1 diabetic children and adolescents.
Inclusion Criteria:

 -  Children and adolescent suffering from type 1 Diabetes Mellitus, for at least 3 years
 from the onset of the disease.

 Exclusion Criteria:

 -  Children with Congenital Heart Diseases.

 -  Children with acquired cardiac diseases.

 -  Children with other systemic diseases.

 -  Symptomatic diabetic cardiomyopathy.