Usefulness of Chromoendoscopy in Diagnosing Microscopic Colitis
Usefulness of Chromoendoscopy in Diagnosing Microscopic Colitis
The purpose of this study is to determine whether chromoendoscopy using Indigo-Carmine dye
 spray is useful in diagnosing microscopic colitis among patients undergoing colonoscopy due
 to chronic watery diarrhea.
Microscopic colitis is a common disease found in 10% to 20% of cases having chronic watery
 diarrhea. Obvious endoscopically identifiable changes of the mucosal surface are usually
 absent, thus diagnosing microscopic colitis relies on multiple biopsy sampling from all
 segments of the colon. Chromoendoscopy using indigo-carmine dye spray might, however, unravel
 mucosal changes in microscopic colitis (Suzuki 2011).

 The aim of this study is to investigate if chromoendoscopy using Indigo-Carmine 0.2-0.5% in
 patients with chronic watery diarrhea is useful in diagnosing microscopic colitis.
Inclusion Criteria:

 -  Patients with chronic non-bloody diarrhea for at least one month

 Exclusion Criteria:

 -  Patients who decline to participate

 -  Unable to give informed consent