Total Post-thyroidectomy Hypocalcemia After Preoperative Cholecalciferol Supplementation
Total Post-thyroidectomy Hypocalcemia After Preoperative Cholecalciferol Supplementation
This prospective study evalue the inflence of pre operative vit D3 administration on post
 operative hypocalcemia in patients undergoing Total thyroidectomy
Thyroidectomy is a frequent procedure. This surgery is well known but not devoid of risks.
 The most common postoperative complication is transitory hypocalcemia. Some studies have
 reported that preoperative vitamin D deficiency (VDD) is a risk factor for hypocalcemia after
 total thyroidectomy (TT) in patients with non toxic multinodular goiter or graves's disease.
 Although the association between VVD and postoperative hypocalcemia in thyroid cancer
 patients undergoing TT plus central compartment neck dissection (CCND) remains unclear. This
 prospective study evalue the inflence of pre operative vit D3 administration on post
 operative hypocalcemia in patients undergoing TT.
Inclusion Criteria:

 -  Patient ≥ 18 years old

 -  Patient shall be operated on for a total thyroidectomy in one time for any indication

 -  Written informed consent (IC) obtained

 -  Patients with affiliation to the social security system

 Exclusion Criteria:

 • Medical history of : Thyroid or parathyroid surgery Hyperparathyroidism Granulomatosis
 flare-up

 -  Hypocalcemia, hypercalcemia/ hypercalciuria, or symptom of Hypocalcemia,
 hypercalcemia/ hypercalciuria, not due to thyroid pathologies

 -  Chronic kidney disease grade ≥4

 -  Severe liver failure

 -  25OHD supplementation within last 3 months before surgery

 -  Malabsorption syndrome

 -  Known hypersensitivity to vitamin D

 -  Medical history of calcic lithiasis

 -  Pregnant women

 -  Vulnerable populations (guardianship or trusteeship)