Comparison of Palonosetron Versus Combination of Palonosetron and Dexamethasone for Preventing Postoperative Vomiting in Patients Receiving Fentanyl by Patient-controlled Analgesia After Minor Orthopedic Surgery
Comparison of Palonosetron Versus Combination of Palonosetron and Dexamethasone for Preventing Postoperative Vomiting in Patients Receiving Fentanyl by Patient-controlled Analgesia After Minor Orthopedic Surgery
Postoperative nausea and vomiting (PONV) is related with extended hospital day and risk
 factor of aspiration pneumonia. Postoperative patient controlled intravenous analgesia is
 related with postoperative nausea and vomiting. Selective 5-HT3 antagonist, Palonosetron, is
 the most recent medication for prevention of PONV. Purpose of our study is comparison of PONV
 preventive effect of palonosetron and combination of palonosetron and dexamethasone.
Inclusion Criteria:

 -  patients who are undergoing minor orthopedic surgery.

 -  IV patient controlled analgesia

 Exclusion Criteria:

 -  1. minority (0~19 year)

 -  patients who are belongs to ASA class 3 or more, and have underlying complicated
 cardiovascular or psychological disease.

 -  Steroid medication

 -  Diabetes Mellitus medication