Effect of Modified Fujita Technique Uvulopalatoplasty on Oxidative DNA Damage Levels in Patients With Obstructive Sleep Apnea SyndromE (OSAS)
Effect of Modified Fujita Technique Uvulopalatoplasty on Oxidative DNA Damage Levels in Patients With Obstructive Sleep Apnea SyndromE (OSAS)
The purpose of this study is to determine the possible effects of uvulopalatopharngoplasty
 (UPPP) -which is a a therapy used on patients with Obstructive sleep apnea syndrome (OSAS- on
 oxidative damage.
Obstructive sleep apnea syndrome (OSAS) is a sydrome which has characteristic upper way
 obstruction and a decrease in blood oxygen saturation as sleeping. uvulopalatopharngoplasty
 (UPPP)is one of the surgical approaches applied to the patients with OSAS, since the
 oxidative damage markers have been found high in patients with OSAS. Although antioxidant
 levels were higher in patients with OSAS than those in normal population, there is report
 about the effect of UPPP on antioxidant status in patients with OSAS. We performed this study
 to confirm whether is there a We performed the present study to confirm whether there is a
 relationship between the OSAS and oxidative damage before and after UPPP.
Inclusion Criteria:

 -  Patients who underwent uvulopalatopharngoplasty (UPPP)for Obstructive sleep apnea
 syndrome (OSAS)

 Exclusion Criteria:

 -  Anormal nasopharyngeal computed tomography, chronic diseases such as diabetes
 mellitus, hypertension etc.