Human Beta-2 Adrenergic Stimulation and Muscle Glucose Uptake
Human Beta-2 Adrenergic Stimulation and Muscle Glucose Uptake
The purpose of this study is to investigate the effect of two weeks clenbuterol/placebo
 supplementation on skeletal muscle glucose disposal in healthy male volunteers.
Inclusion Criteria:

 1. Caucasian;

 2. Male sex;

 3. Age: 18-30

 4. BMI: 18-25 kg/m2;

 5. Normal physical activity levels;

 Exclusion Criteria:

 1. Not meeting all inclusion criteria

 2. Cardiovascular diseases (determined by means of questionnaires, heart rate/blood
 pressure measurements)

 3. Respiratory diseases (including asthma, bronchitis and COPD);

 4. Unstable body weight (weight gain or loss > 5 kg in the last three months);

 5. Intention to lose or gain body weight (e.g. with caloric restriction or physical
 activity)

 6. Excessive alcohol and/or drug abuse;

 7. Hypokalaemia;

 8. Hb < 8.4 mmol/L;

 9. Epilepsy;

 10. Smoking;

 11. Renal and/or liver insufficiency;

 12. Participation in another biomedical study within 1 month before the first study visit,
 possibly interfering with the study results;

 13. Medication use known to hamper subject's safety during the study procedures;

 14. Subjects who do not want to be informed about unexpected medical findings;

 15. Subjects who do not want that their treating physician to be informed;

 16. Inability to participate and/or complete the required measurements;

 17. Participation in organised or structured physical exercise;

 18. Any condition, disease or abnormal laboratory test result that, in the opinion of the
 Investigator, would interfere with the study outcome, affect trial participation or
 put the subject at undue risk;

 19. Hyperthyroidism