Predictors of Upper Airway Function and Sleep-disordered Breathing in the Critically Ill
Predictors of Upper Airway Function and Sleep-disordered Breathing in the Critically Ill
This is part 2 of the #NCT01618240 under the same IRB protocol #2010P001919. The primary
 objective of this study is to examine factors that are related to sleep-disordered breathing
 and upper airway patency in critically ill patients who have been recently mechanically
 ventilated. Our primary hypothesize is that sedatives and neuromuscular blocking agents given
 in the ICU prior to extubation and during the first night following extubation are associated
 with sleep-disordered breathing. The secondary hypotheses are that duration of mechanical
 ventilation, BMI, and muscle strength are associated with sleep-disordered breathing during
 the night after extubation.

 The secondary objective is to evaluate if sleep-disordered breathing in the ICU can be
 predicted by standard pulmonary function testing in the ICU.
Inclusion Criteria:

 1. Patients admitted to the SICU

 2. Age over 18 years.

 3. Ventilated patients with an endotracheal tube for at least 24 hours.

 Exclusion Criteria:

 1. Decreased level of consciousness as defined by a Richmond Agitation Sedation Scale
 (RASS) of 0.

 2. Non-cooperative patient, CAM score positive for risk of delirium.

 3. For women: pregnancy.