Prognostic and Predictive Factors for Small Breast Tumors
Prognostic and Predictive Factors for Small Breast Tumors
Because of mammography screening increasingly more women are diagnosed with centimeter or
 subcentimeter node-negative breast cancer (i.e., T1abN0); these tumors account for
 approximately 19% of all newly diagnosed breast cancers in Sweden. Although the long term
 relapse-free survival rates among patients with such tumors is as high as ≥90%, some reports
 suggest that certain patient subgroups may have rates <75%. Firmly established prognostic and
 predictive factors for patients with T1abN0 tumors are, however, lacking. This is a
 nationwide, register-based cohort study investigating prognostic and predictive factors in
 women with centimeter or subcentimeter breast cancer. The study hypotheses are: 1)
 Established prognostic and/or predictive factors in overall breast cancer are prognostic
 and/or predictive factors also in centimeter or subcentimeter node-negative breast cancer; 2)
 The established relative reduction in risk of recurrence and death of adjuvant treatment for
 overall breast cancer are similar in centimeter or subcentimeter node-negative breast cancer.
Inclusion Criteria:

 1. Female.

 2. Operated for centimeter or subcentimeter breast cancer.

 Exclusion Criteria:

 1. Previous breast cancer.

 2. Metastatic breast cancer at diagnosis.