Oncologic Impact of Splenectomy-omitting Radical Pancreatectomy in Well-selected Left-sided Pancreatic Cancer
Oncologic Impact of Splenectomy-omitting Radical Pancreatectomy in Well-selected Left-sided Pancreatic Cancer
When distal pancreatectomy is carried out for left-sided pancreatic cancer, splenectomy is
 usually performed not only for margin-negative resection but also for effective clearance of
 the splenic hilar lymph nodes. However, there was no scientific evidence regarding the
 justifiability for spleen resection. Considering potential immunological function of the
 spleen, the investigators hypothesized that distal pancreatectomy without pancreatectomy for
 left-sided pancreatic cancer is superior than Distal pancreatectomy with pancreatectomy in
 terms of short-term perioperative outcomes and disease-specific overall survival.
Inclusion Criteria:

 1. Ductal adenocarcinoma

 2. Age ≥20 and ≤80

 3. General performance status: the Karnofsky score> 70% or ECOG 0-1

 4. Potentially Curative resection

 5. Tumor size < 3cm

 6. Pancreatic cancer located on neck or body portion

 7. No invasion to spleen or spleen hilum

 8. No combined resection except Lt. adrenal gland

 9. Distance more than 5cm (≥5cm) between tumor lateral margin and spleen hilum

 Exclusion Criteria:

 1. Unresectable or locally advanced, metastatic case

 2. Patients who do not want surgery

 3. ASA (American society of anesthesiologists' physical status classification) score: ≥3

 4. Patients with drug or alcohol addiction

 5. Patients showing low compliance

 6. Patients who not want to involve the clinical trial

 7. Patients who are unable to read or understand the informed consent, sign a consent
 form (eg, mental retardation, blindness, illiteracy, foreign, etc.)