A Study of MHE in Patients With Liver Diseases
A Study of MHE in Patients With Liver Diseases
The investigators analyze the diagnostic efficacy of blood ammonia,
 neurophysiological/psychological tests and blood markers on MHE; to see the progression of HE
 under the condition of the drugs intervention and no drugs intervention in clinical real
 world.
In China, hepatic encephalopathy (HE) is a common complication and one of the most serious
 manifestations of liver disease, not only increasing the risks of death, but also seriously
 affecting the lives of the patients and their caregivers. CHE includes the 1st stage of HE
 and minimal encephalopathy (MHE). It has indicated in a study that the mortality rates of
 covert hepatic encephalopathy (CHE) and overt hepatic encephalopathy (OHE) were both high
 (21% and 21.8% respectively). At present, CHE, especially MHE, is not easy to diagnose in
 daily clinical work. This study aims to early diagnose MHE and find suitable treatment to
 benefit patients. The investigators analyze the diagnostic efficacy of blood ammonia,
 neurophysiological/psychological tests and blood markers on MHE; to see the progression of HE
 under the condition of the drugs intervention and no drugs intervention in clinical real
 world.
Inclusion Criteria:

 -  >18 years old

 -  cirrhosis

 -  acute on chronic liver failure

 -  severe liver diseases

 Exclusion Criteria:

 -  liver cancer

 -  other malignancy

 -  poor eyesight

 -  uncooperative