Relation of Glucose and Acute Pancreatitis
Relation of Glucose and Acute Pancreatitis
Acute pancreatitis (AP) is an acute inflammatory disease of the pancreas which can lead to a
 systemic inflammatory response syndrome with significant morbidity and mortality in 20% of
 patients. Part of endocrine function of pancreas would be affected in AP. Stress
 hyperglycemia would explode at acute phase. So the investigators decide to follow up and
 observe 200 cases of patients with acute pancreatitis, determining of blood sugar, blood
 amylase, hemoglobin and glycosylated hemoglobin level. At last, using ROC curve method to
 identify the die cutting between blood glucose level and acute pancreatitis, and makes
 analysis of the diagnostic value.
Acute pancreatitis (AP) is an acute inflammatory disease of the pancreas which can lead to a
 systemic inflammatory response syndrome with significant morbidity and mortality in 20% of
 patients. Part of endocrine function of pancreas would be affected in AP. Stress
 hyperglycemia would explode at acute phase. There are two reasons. One is because that
 sympathetic hyperactivity makes glucagon elevated. Secondary, microcirculation disorder makes
 pancreas edema, ischemia and necrosis, affecting secretion and excretion of insulin. In
 severe acute pancreatitis, there may be ketoacidosis. Many scoring systems for predicting
 prognosis of severe acute pancreatitis also contains glucose values, such as the Ranson
 scoring system and the Glascow scoring system. On the other hand, Type 2 diabetes has become
 a global pandemic disease. Most of patients of type 2 diabetes are obese, who easily
 complicated gallstone disease and hypertriglyceridemia. All of above could be the risk
 factors for acute pancreatitis. Our initial small sample research also suggests undiagnosed
 diabetes patients whose glucose value elevated is significantly worse than the known diabetic
 patients. Therefore, the investigators believe that glucose directly affects the prognosis of
 AP. So the investigators decide to follow up and observe 1000 cases of patients with acute
 pancreatitis, determining of blood sugar, blood amylase, hemoglobin and glycosylated
 hemoglobin level. At last, using ROC curve method to identify the die cutting between blood
 glucose level and acute pancreatitis, and makes analysis of the diagnostic value.
Inclusion Criteria:

 patients that newly diagnosed as acute pancreatitis.

 Exclusion Criteria:

 exclude other acute abdomen, such as peptic ulcer with perforation, mesenteric arterial
 embolism or ruptured ectopic pregnancy.