Comparing Individualized vs. Weight Based Protocols to Treat VOE in SCD Occlusive Episodes in Sickle Cell Disease
Comparing Individualized vs. Weight Based Protocols to Treat VOE in SCD Occlusive Episodes in Sickle Cell Disease
The purpose of this research study is to compare two different ways to give opioid pain
 medicine to treat sickle cell disease pain that is bad enough to go to the emergency
 department for treatment. One way uses your weight to decide how much pain medicine to give
 you while in the emergency department. This is called weight based treatment. The other way
 uses how much pain medicine you take at home and how much medicine you needed during past
 emergency department visits to decide how much medicine to give you. This is called patient
 specific treatment.
Inclusion Criteria:

 -  All adult (18 years or older);

 -  SCD patients with the following genotypes: Hgb SS, SC, and SB+ and SB- thalassemia

 Exclusion Criteria:

 -  determined to not benefit from opioids and therefore won't receive opioids in any
 future ED visit.