Is There a Metabolic Effect of Cinnamon on HbA1c, Blood Pressure and Serum Lipids in Type 2 Diabetes Mellitus?
Is There a Metabolic Effect of Cinnamon on HbA1c, Blood Pressure and Serum Lipids in Type 2 Diabetes Mellitus?
The aim of the study is to assess whether dietary supplementation of cinnamon (cinnamon
 cassia) has the potential to improve HbA1c, blood pressure and serum lipid measurements in
 patients with type 2 diabetes mellitus.
The study will be conducted for 3 months (12 weeks) with 58 individuals diagnosed with type 2
 diabetes mellitus. The randomisation will be carried out by using a randomisation list.
 Cinnamon bark (cinnamon cassia) and starch flour (placebo) capsules will be purchased from a
 local pharmaceutical company in UK; these are freely available for over the counter use. Each
 capsule contained either 500 mg of cinnamon powder or starch flour. The cinnamon and placebo
 (starch flour) capsules will be packaged in a non transparent plastic bags.

 The patients will be randomly allocated into the two groups of:

 Group 1: placebo control group Group 2: cinnamon group

 Patients in both placebo and cinnamon groups will receive treatment similar to the treatment
 they would normally receive from their respective NHS or primary care trust for 12 weeks.

 Data collection:

 After the randomisation the subjects will be scheduled to visit the clinic at 0 weeks, 6 - 7
 weeks and 12 weeks from the beginning of the study. During every visit (week 0, weeks 6 - 7
 and week 12) a 3-day diet diary will be collected and the intake of total calories, fats,
 carbohydrates, proteins and fibre will be determined. Compliance with the diet will be
 monitored by individual discussions at each clinical visit with dietician and compared with
 the diet diary. The anthropometric measurements of body weight, height, waist and hip
 circumferences will be measured before the trial (week 0), during the trial (weeks 6 - 7) and
 after the trial (week 12) period. The recorded clinical measurements of blood profiles
 include HbA1c level, fasting plasma glucose concentration and serum lipid profiles including
 serum total cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL) and
 serum triglycerides, systolic and diastolic blood pressures will be measured at the baseline
 (week 0) and at 12 weeks during the study period.
Inclusion Criteria:

 1. Patients diagnosed with type 2 diabetes mellitus

 2. Aged over 18 years, either sex

 3. HbA1c level more than 7%

 4. Patients treated only with oral anti-diabetic drugs or diet

 Exclusion Criteria:

 1. Patients with severe health problems including renal disease, liver disease,
 cardiovascular disease and other chronic ill health conditions

 2. Patients with mental health problems

 3. Patients treated with insulin therapy

 4. Patients refused to give informed consent

 5. Pregnant and lactating women

 6. Patients taking cinnamon supplements and other herbal supplements known to be
 effective