Study Comparing Olanzapine With Haloperidol for the Relief of Nausea and Vomiting in Patients With Advanced Cancer
Study Comparing Olanzapine With Haloperidol for the Relief of Nausea and Vomiting in Patients With Advanced Cancer
The purpose of this study is to compare the efficacy and safety of Haldol (haloperidol) and
 olanzapine in the control of chronic nausea with advanced cancer patients who have failed
 first line antiemetic therapy.
The purpose of this study is to compare the efficacy and safety of haloperidol and olanzapine
 in the control of chronic nausea with advanced cancer patients who have failed first line
 antiemetic therapy.
Inclusion Criteria:

 -  >18 years of age

 -  Significant nausea/vomiting

 -  Failed maxeran and domperidone

 -  Underlying treatment of causes has failed

 -  Adequate cognitive function

 -  Communicates well

 Exclusion Criteria:

 -  Partial/complete bowel obstruction

 -  Currently taking Haldol or olanzapine

 -  Has drug induced extrapyramidal symptoms

 -  Parkinson's disease

 -  Undergoing chemotherapy or radiotherapy (RT) to brain, abdomen, stomach or esophagus