Operative Mitral Valve Reconstruction in Functional mv Insufficiency With Reduced Systolic Ventricle Function
Operative Mitral Valve Reconstruction in Functional mv Insufficiency With Reduced Systolic Ventricle Function
Functional mitral insufficiency poses a challenge with regard to the optimal time of
 intervention, particularly because they are frequently associated with left ventricular (LV)
 dilation and reduced LV ejection fraction (EF). The registry will document the underlying
 pathology by using transthoracal echo cardiography (TTE) with analysis of common tenting
 parameters. OP strategies, data and outcomes will be documented, as well as follow-up data
 for echocardiography, quality of life and MACCE outcomes after 6 months, 1 and 2 years.
Prospective enrolment of all patients with mitral valve insufficiency and restricted movement
 of leaflets during systole into a multicentric registry. Exact analysis of the underlying
 pathology using TTE with analysis of tenting parameters. In patients without
 contraindications, functional preoperative MRT to determine the functional reserve of
 ventricular function. Documentation of the quality of life of the patients using the SF12
 questionnaire before and after intervention. Documentation of follow-up data (SF12, TTE,
 NT-pro BNP) at 6 months, 1 and 2 years. Development of operative strategies to improve
 long-term outcomes in patients with severe LV dilation (typically accompanied by function
 mitral insufficiency type IIIb).
Inclusion Criteria:

 -  functional mitral valve insufficiency with reduced mobility of leaflets during systole
 (type IIIb) - effective regurgitation orifice area > 20 mm2 / regurgitant volume > 30
 ml/beat

 -  left ventricular ejection fraction <= 50% and /or left ventricular end-diastolic
 diameter >= 60 mm

 -  tenting of the proximal and / or anterior mitral leaflets

 Exclusion Criteria:

 -  prolaps of leaflets (type II mitral regurgitation)

 -  combination intervention with aortic valve repair or replacement

 -  re-operation at mitral valve