Randomized Clinical Trial of Polyester vs. Polyurethane Patch for Carotid Endarterectomy
Randomized Clinical Trial of Polyester vs. Polyurethane Patch for Carotid Endarterectomy
This study examines the risk of thrombogenicity of the carotid patches in polyurethane
 compared to carotid patches in polyester including death, any stroke, carotid thrombosis at
 30 days and long-term results including stroke and recurrent carotid stenosis at 10 years.

 This study was run at the University of Roma, La Sapienza and at the University of Poitiers,
 randomisation was done in both enters after approval by the Ethical committee of the
 University of Roma (Record uploaded)
This study examines the risk of thrombogenicity of the carotid patches in polyurethane
 compared to carotid patches in polyester including death, any stroke, carotid thrombosis at
 30 days and long-term results including stroke and recurrent carotid stenosis at 10 years.

 598 patients were considered for randomisation between January 1995 and January 2004. The
 following patients were excluded for randomisation (Redo carotid surgery: N=34, radiation
 induced carotid stenosis:N=45, indication for carotid bypass: N=65, Refusal of randomisation:
 N=4).

 In total, 450 patients were randomized in two groups, 225 received a polyester patch and 225
 received a polyurethane patch.

 All patients were operated under general anaesthesia and all received an intraoperative
 angiography. A shunt was selectively used in patients with a recent stroke (<15 days) or with
 a contralateral carotid occlusion
Inclusion Criteria:

 -  Carotid stenosis > 60% NASCET criteria

 Exclusion Criteria:

 -  Redo carotid surgery

 -  Radiation induced carotid stenosis

 -  Extensive carotid lesion > 5 cm in length with involvement of the common carotid
 artery best treated by a carotid bypass