Follow-up Study of Complications of Acute Pancreatitis
Follow-up Study of Complications of Acute Pancreatitis
This is a follow-up study focusing on long-term complications of acute pancreatitis. The
 primary purposes include: 1. To assess the incidence of type 2 diabetes
 mellitus（2-DM）,impaired glucose tolerance, metabolic abnormalities of blood lipids after
 acute pancreatitis. 2. To observe the possible long-term clinical outcomes after acute
 pancreatitis attack, which may include: chronic pancreatitis, pancreatic cancer,
 pancreatogenic portal hypertension, autoimmune pancreatitis et al. 3. To evaluate the
 long-term influence of acute lung injury(PaO2/FiO2<200,FiO2 means fraction of inspiration O2)
 in AP patients during ICU stay on life qualities of the patients; 4. To observe the prognosis
 of the local complications of acute pancreatitis(AP) patients; it might be helpful to find
 the most effective and targeted interventions aiming at different phases after AP attack.
Currently，follow-up study is limited on glucose intolerance and life quality assessment.
 However, it has been shown that AP is associated to some extent with other diseases such as
 chronic pancreatitis, pancreatic cancer, pancreatogenic portal hypertension and autoimmune
 pancreatitis; In addition, for patients who have severe lung injury following AP, especially
 with PaO2/FiO2<200 during ICU stay, the long term prognosis remains unclear. Thus, a large
 sample follow-up study is essential for elucidating the possible long-term complications.

 Prior to follow up study, the investigators performed baseline analysis of AP patient data
 from the database of the First Affiliated Hospital of Nanchang University. It is estimated
 that 1300 patients will be interviewed over telephone and 600 patients in the outpatient
 department. The content of the follow-up includes: questionnaire (the MOS[medical outcome
 study] item short from health survey, SF[short form]-36) ; lab testing(complete blood count,
 blood chemistry such as liver and kidney function, C-reaction protein(CRP), AMY, fasting
 blood-glucose，1 and 2 hour postprandial blood glucose,C-peptide, blood lipids, FE-1) and CT
 scan. For patients who have severe lung injuries during ICU stay, pulmonary function test,
 Blood gas analysis and chest CT will be performed. After screening, the patients with chronic
 pancreatitis(CP), pancreatic cancer(PC), post Pancreatogenic portal hypertension（PPH） or
 autoimmune pancreatitis(AIP）will be hospitalized for further therapy.
Inclusion Criteria:

 -  Clinical diagnosis of acute pancreatitis from our hospital

 -  Must be signed the informed consent

 Exclusion Criteria:

 -  Failed to complete the questionnaire survey and the follow-up examination