The Effect of Ketogenic Diet on Malignant Tumors- Recurrence and Progress
The Effect of Ketogenic Diet on Malignant Tumors- Recurrence and Progress
The aim of the study is, to study the efficacy of the ketogenic diet in delaying or
 preventing recurrence and tumor growth progression of patients who have been previously
 treated by concomitant chemoradiotherapy (6 months) for high-grade glial tumors.

 It will be an open-label trial of nutritional intervention for up to 1 year. An interim
 analysis of the data will be carried out to assess safety, compliance and efficacy of the
 diet. This will be reviewed by both SHS and the Clinical trial team.
Inclusion criteria:

 1. Consenting adults aged ≥ 18 years.

 2. Recurrent or progressive high grade glioma after failure of at least one line of
 standard oncological treatment.

 3. Gliomatosis cerebri, including patients declining radiation treatment.

 Exclusion criteria:

 1. Patients with malignant tumors who are receiving treatment at the time of the
 recruitment.

 2. Early termination - patients who will wish to stop their participation in the trial
 will discontinue the ketogenic diet and return to their usual diet.