The Effect of Breakfasts Varying in Protein Source on Appetite and Energy Intake
The Effect of Breakfasts Varying in Protein Source on Appetite and Energy Intake
Over the last decades, changes in the diet and lifestyle have led to overall energy imbalance
 becoming commonplace and the emergence of an obesity epidemic with more than 1.6 billion
 adults being overweight.

 Consumption of foods that can affect appetite by increasing satiety could regulate the total
 energy intake and thus body weight. There is data suggesting that the macronutrient
 composition of the foods and especially protein content may have a potent role on satiety.
 However, the type of protein appears to play a role in satiety possibly due to the different
 balance of the amino acid profile.

 The research project is dedicated to identify the source (animal or plant) and the optimized
 protein quantity needed to accelerate satiation, suppress appetite and extend satiety until
 hunger appears again.

 It is hypothesized that the consumption of animal derived protein-enriched meals will induce
 a reduction in hunger through the impact on gut hormones and peptides that are closely
 related to the short-term regulation of food intake.
Inclusion Criteria:

 -  Healthy males

 -  Age range 18-50 years

 -  Normal weight and overweight people as classified by BMI:20-29.9 kg/m2 (inclusive).

 -  Weight stable (within 3 kg) two months prior to study inclusion

 -  Understanding English well and feeling comfortable speaking it

 Exclusion Criteria:

 -  Dietary protein consumption >25% energy from protein

 -  Had surgery in the previous 12 months

 -  Have suffered a myocardial infarction or stroke at any time

 -  Suffer from any blood-clotting disorder or prescription of any medication affecting
 blood clotting

 -  Suffer from any metabolic disorders (e.g. diabetes, metabolic syndrome or
 hypertension)

 -  Any requirement to take long-term medication, especially those active on the
 gastro-intestinal tract or for cardio-vascular disease

 -  Any dietary restrictions or recently/currently on a weight reducing diet

 -  Irregular eating patterns or not regularly consuming breakfast

 -  Food allergies (e.g. milk protein allergies) or intolerances (e.g. lactose)

 -  Use of medication which affects food intake or behaviour (e.g. anti-depressants)

 -  Use of medication likely to affect taste, smell or appetite

 -  Eating restraint based on the three Factor Eating Questionnaire

 -  Use of any protein supplements

 -  A history of alcohol or drug misuse (the average daily number of units of alcohol
 considered as acceptable is 2-3 units women; 3-4 units men

 -  Smoking

 -  Athletes in training (>10 h exercise/week)

 -  Female that is breast-feeding, pregnant, or if of child-bearing potential and are not
 using effective contraceptive precautions

 -  Involvement in a study involving an experimental drug/medication within 3 months prior
 to entry of this study

 -  Blood pressure > 160/90 mmHg

 -  Vegan or Vegetarian

 -  Glucose > 6 mmol/L

 -  Gamma glutamyl transpeptidase (liver enzymes) > 1.9 μkat / L

 -  Alanine aminotransferase > 1.1 μkat / L

 -  Cholesterol > 6.5 mmol/L

 -  Triglycerides > 2.0 mmol/L