Effect of Portal Vein Thrombosis on the Prognosis of Liver Cirrhosis
Effect of Portal Vein Thrombosis on the Prognosis of Liver Cirrhosis
The prevalence of portal vein thrombosis (PVT) in patients with liver cirrhosis is 5-20%.
 Current evidence regarding the effect of portal vein thrombosis on the prognosis of cirrhotic
 patients remains under debate. Considering that PVT potentially elevates the portal pressure
 and thereby increase the risk of variceal bleeding, we focus on the patients with high-risk
 varices and variceal bleeding as the study population. Thus, the main goals are to analyze
 the effect of PVT on the incidence of first variceal bleeding in patients without any prior
 bleeding history but with high-risk varices, the incidence of recurrent variceal bleeding in
 patients with a history of variceal bleeding, and the treatment failure rate of variceal
 bleeding in patients with acute variceal bleeding. Certainly, the survival is also observed
 in all patients.
Inclusion Criteria:

 1. A diagnosis of liver cirrhosis.

 2. Patients should be diagnosed with high-risk varices endoscopically, or a prior history
 of variceal bleeding, or an episode of acute variceal bleeding.

 3. Patients agreed to undergo endoscopy to evaluate the presence and severity of varices.

 4. Patients agreed to undergo contrast-enhanced CT scans to evaluate the portal vein
 patency. But if an abdominal contrast-enhanced CT scans was performed within 3 months
 after admission, it was not necessarily repeated.

 Exclusion Criteria:

 1. Non-cirrhotic patients.

 2. Malignancy.

 3. Contrast-enhanced CT scans were neither feasible nor available.

 4. Severe cardiopulmonary diseases.

 5. Severe infectious diseases.

 6. Pregnant or breastfeeding.

 7. Allergic to contrast agents.

 8. Poor adherence.