Impact of a LCD on Metabolic Inflexibility and Cardiovascular Risk in Liver Transplant Patients
Impact of a LCD on Metabolic Inflexibility and Cardiovascular Risk in Liver Transplant Patients
This study is looking to see how a 6-month low carbohydrate diet can affect the body's
 ability to use energy in addition to the affects it has on the heart and blood vessel health.
Weight gain often occurs following a liver transplant. This weight gain is problematic as it
 leads to many other health problems. The reasons of this weight gain are still poorly
 understood. To better understand weight gain, this study is looking to see how a 6-month low
 carbohydrate diet can affect the body's ability to use energy in addition to the affects it
 has on heart and blood vessel health.

 This study will help researchers to better understand weight gain after a transplant. This
 knowledge will help doctors prevent weight gain after a liver transplant and therefore
 improve the health of liver transplant patients.
Inclusion Criteria:

 -  Age > 18 years

 -  At least 12 months after LT

 -  Obese (BMI > 30kg/m2)

 Exclusion Criteria:

 -  Acute cellular or chronic rejection within 3 months

 -  Post-LT liver or non-liver related malignancy

 -  Active viral hepatitis (B or C), autoimmune hepatitis

 -  Untreated biliary strictures or vascular complications (i.e. hepatic artery
 thrombosis)

 -  Poorly controlled Diabetes mellitus

 -  Relapse of alcohol abuse after LT

 -  Stage 5 Chronic Kidney Disease

 -  Current pregnancy