Active Surveillance of Papillary Thyroid Microcarcinoma
Active Surveillance of Papillary Thyroid Microcarcinoma
Papillary thyroid microcarcinoma are small thyroid cancer measuring 1cm or less. Most of this
 tumor are not palpable and are identified either through pathologic examination or from
 imaging modalities, such as CT scan or thyroid sono. Active surveillance of papillary
 microcarcinoma is to observe thyroid papillary cancer without immediate surgical approach.
 The purpose of this study is to understand more about the characteristics of papillary
 microcarcinoma, which has been known for "the cancer slowly progression"
Inclusion Criteria:

 1. < 1 cm solitary nodule

 2. Surrounded by ≥ 2 mm normal thyroid parenchyma

 3. Subcapsular locations not adjacent to surrounding structures, recurrent laryngeal
 nerve, trachea, or carotid artery

 4. No evidence of invasion to surrounding structures, recurrent laryngeal nerve, trachea
 or carotid artery

 5. No extrathyroidal extension

 6. Clinically N0 and Clinically M0

 7. ≥ 18 years

 8. Combined severe comorbidities or Inoperable condition (optional)

 9. No wish to surgery and Willingness to accept active surveillance

 10. No history of radiotherapy on head and neck area

 11. Accepted by the Board of Thyroid Cancer Meeting

 Exclusion Criteria:

 1. ≥ 1 cm nodule and multifocal nodules regardless of size

 2. Papillary thyroid carcinoma variants associated with poor prognosis (tall cell
 variant, columnar variant, hobnail variant) or other types of thyroid cancer)

 3. Subcapsular locations adjacent to surrounding structures, recurrent laryngeal nerve,
 trachea or carotid artery

 4. Evidence of invasion to surrounding structures, recurrent laryngeal nerve, trachea or
 carotid artery

 5. Extrathyroidal extension

 6. Any of N1 or M1

 7. Documented increase in size according to America Thyroid Association (ATA) guideline
 in a previously confirmed Papillary thyroid microcarcinoma

 8. < 18 years

 9. Not willing to accept observational active surveillance approach