Adiponectin and Circulating Progenitor Cells (CPC) Function
Adiponectin and Circulating Progenitor Cells (CPC) Function
Adiponectin and exercise training contribute to the maintenance of a normal vascular tone by
 influencing vascular NO bioavailability and concentration and function of endothelial
 progenitor cells. The molecular mechanisms are only partially understood. Therefore, aim of
 the present study is to elucidate the effects of Adiponectin on endothelial progenitor cell
 migration and the underlying signaling pathways. Furthermore, the impact of exercise training
 on adiponectin-mediated endothelial progenitor cell migration will be investigated.
Inclusion Criteria:

 -  ≤ 75 years of age

 -  stable coronary artery disease

 -  preserved left ventricular function

 -  physical work capacity of ≥ 50

 -  successful elective percutaneous coronary intervention at study begin

 Exclusion Criteria:

 -  diabetes mellitus

 -  hypercholesterolemia

 -  untreated hypertension

 -  smoking

 -  myocardial infarction within the last 4 weeks

 -  significant stenosis of the left main coronary artery