APAP +/- Oxycodone
APAP +/- Oxycodone
This is an emergency department based randomized study of oxycodone/ acetaminophen versus
 acetaminophen alone for patients with acute musculoskeletal pain refractory to ibuprofen
Inclusion Criteria:

 -  Acute musculoskeletal pain: Any pain attributable to muscles, bones, joints, tendons,
 ligaments or supporting structures, as determined by the clinical team, of 10 days
 duration or less. Prior to the onset of acute pain, patients cannot have experienced
 pain in the same body region during the prior six months

 -  Pain has to be described as moderate or severe, when the patient is asked if the pain
 is mild, moderate or severe in intensity

 Exclusion Criteria:

 -  Use of an non-steroidal anti-inflammatory drug within the previous six hours

 -  Use of acetaminophen within the previous six hours

 -  Use of an opioid within the previous ten days

 -  Chronic pain, defined as any pain on >50% of days for at least 3 months prior to onset
 of acute pain

 -  Gout