Treatment With Topical Eflornithin After Laser Treatment in Women With Facial Hirsutism
Treatment With Topical Eflornithin After Laser Treatment in Women With Facial Hirsutism
Split-face investigation of the efficacy of applying Eflornithin cream twice daily for six
 months after a period with six laser treatments for hair removal.
Background: Unwanted facial hair growth is a serious problem for 5-15% of all women winch
 affects their quality of life. In Denmark patients are offered six laser treatments covered
 by the public health insurance. There is a lack of good follow-up treatments to this regime
 that can extent the efficacy of the laser treatment. Eflornithin cream is an approved
 treatment for reduction of facial hair growth which has proved to give an additional
 efficiency when used in combination with laser treatments.The efficacy when used after laser
 hair removal is not known.

 Aim: To investigate whether an extended efficacy of laser hair removal can be achieved with
 application of Eflornithin cream twice daily for six months after completion of laser
 treatments.

 Method: in a split-face trial to apply Eflornithin cream twice daily for six months. Outcome
 measures are investigator evaluation, blinded on-site evaluation, patient's assessment score
 and clinical photos.
Inclusion Criteria:

 -  18 years or older

 -  habile, understands Danish

 -  moderate to severe hirsutism prior to laser treatments

 -  succeeded minimum five laser treatments

 -  intact skin with no severe adverse events to laser treatments

 -  record of current medication and androgen hormone blood profile available

 -  Use of safe anti-conception (fertile women)

 Exclusion Criteria:

 -  Pregnant or lactating

 -  allergy toward the content of Eflornithin cream

 -  Concomitant use of immunosuppressive therapy

 -  Dementia, psychiatric disease, alcoholic