Factors Associated To Intensive Care Admission And Mortality In Patients With Emphysematous Pyelonephritis
Factors Associated To Intensive Care Admission And Mortality In Patients With Emphysematous Pyelonephritis
Emphysematous pyelonephritis is a lifethreatening necrotizing infection of the kidney
 characterized by accumulation of gas in the renal parenchyma and within the surrounding
 tissues. The aim of the study is to report the outcome of the management of this condition at
 the investigators institution and to determine the microbiological characteristics,
 antibiotic resistance patterns, and to analyze factors predicting mortality and intensive
 care unit admission.
The investigators are planning to perform a retrospective study analyzing cases of
 emphysematous pyelonephritis from a single tertiary care institution in the north of Mexico
 in the period of 2011-2021. The diagnosis of emphysematous pyelonephritis is confirmed by
 computed tomography. Demographic, clinical, biochemical, therapeutic management, and outcomes
 will be collected. Variables will be analyzed to determine factors associated with admission
 to intensive care unit and mortality. Urine cultures will be analyzed and drug resistance
 profile will be determined using microdilution plate. Clinical and demographic
 characteristics will be analyzed using Chi square test for categorical variables, and T-test
 for numerical variables. Statistical significance is set at p<0.05. Statistical analysis will
 be performed with the SPSS software version 20.0.
Inclusion Criteria:

 -  Emphysematous pyelonephritis confirmed with computed tomography

 -  Systemic inflammatory response

 -  Urinary tract infection symptoms

 -  Complete medical records

 -  Both genders included

 -  >18 years old

 Exclusion Criteria:

 -  Other infectious causes

 -  Asymptomatic bacteriuria

 -  Incomplete medical records

 -  Endourologic procedure 3 months before recruitment