Multicenter Registry Comparing Preoperative Imaging for Primary Hyperparathyroidism
Multicenter Registry Comparing Preoperative Imaging for Primary Hyperparathyroidism
The study aims are:

 1. To compare the diagnostic performance of parathyroid four-dimensional CT (4D-CT),
 scintigraphy, and ultrasound in patients who underwent parathyroid surgery for primary
 hyperparathyroidism.

 2. To compare 4D-CT, scintigraphy, and ultrasound for the ability to perform focused
 parathyroidectomy, and for rates of persistent hyperparathyroidism and complications
 from parathyroid surgery.

 Methods The investigators will create a multicenter registry consisting of patients having
 parathyroid surgery for primary hyperparathyroidism from July 2009 to June 2016. Initial
 participating centers include Duke University Medical Center, University California Los
 Angeles (UCLA) and University of Arkansas for Medical Sciences (UAMS).

 There will be no intervention in the patient's treatment or imaging. The management will be
 determined by the surgeon or clinician supervising the patient's care.

 The registry will consist of patient data regarding basic demographics, history of prior
 neck/chest surgery or radiation, parathyroid imaging, biochemical evaluation, intraoperative
 surgical findings, parathyroid pathology, and surgical outcomes within the first 6 months
 (persistent disease, recurrent laryngeal nerve injury, and hypoparathyroidism). Data will be
 entered into REDCap with no PHI. The investigators expect to include 3000 patients in the
 registry (1000 from Duke).
Inclusion Criteria:

 -  patients having parathyroid surgery for primary hyperparathyroidism from July 2009 to
 June 2016

 Exclusion Criteria:

 -  age less than 18 years

 -  parathyroid carcinoma

 -  secondary or tertiary hyperparathyroidism