Preoperative Biliary Drainage for Resectable Hilar Cholangiocarcinoma
Preoperative Biliary Drainage for Resectable Hilar Cholangiocarcinoma
This study is to investigate whether preoperative biliary drainage can reduce the
 postoperative morbidity in patients with hilar cholangiocarcinoma.
Preoperative biliary drainage(PBD) or not, is a Hot Spot issue in the management of Hilar
 cholangiocarcinoma. Surgeons from Japan tend to perform PTBD(Percutaneous Transhepatic
 Biliary Drainage) before a definite operation until the total bilirubin(TB) lower than
 85μmol/L. For some patients needed to perform extended curative resection, PVE(Portal Vein
 Embolization) is performed and thus the duration of PBD may be around six weeks and the final
 TB is lower than 34μmol/L. Some tend to perform a definite curative operation in a short time
 after diagnosis. There is no RCT research on the effect of PBD for the resectable Hilar
 Cholangiocarcinoma patients to date.
Inclusion Criteria:

 -  Patients newly diagnosed

 -  Resectable patients after imaging assessment and evaluation of general condition of
 the patient

 -  TB>85μmol/L

 -  WBC account more than 1.5×109/L, PLT account more than 100×109/L and HB account more
 than 100g/L

 -  No serious disease in heart, lung and kidney

 -  Written informed consent

 Exclusion Criteria:

 -  Unresectable patients.

 -  Patients have received biliary drainage procedure such as PTBD before admission

 -  Complicated with chronic hepatitis

 -  Myocardia infarction record within six months

 -  Women in pregnancy

 -  Serious disease in heart, lung or kidney