Detection of Functioning Pituitary Microadenoma: PET/MRI Versus PET/CT
Detection of Functioning Pituitary Microadenoma: PET/MRI Versus PET/CT
This is a prospective case-control study to compare the usefulness of 18F-FDG PET/MRI with
 that of 18F-FDG PET/CT in detection of functioning pituitary microadenomas.A single dose of
 370 Mega-Becquerel (MBq) 18F-FDG will be injected intravenously.Visual and semiquantitative
 method will be used to assess the PET/MRI and PET/CT images.
Magnetic resonance imaging (MRI) may be insufficient to locate functioning pituitary
 microadenoma.This study compared the usefulness of 18F-FDG PET/MRI with that of 18F-FDG
 PET/CT in detection of functioning pituitary microadenomas in patients with inconclusive
 conventional MRI findings. Trans-sphenoidal adenomectomy was performed within 2 weeks of
 imaging.The PET/CT and PET/MRI findings and tracer uptake levels were correlated with the
 surgical findings and pathological results.
Inclusion Criteria:

 -  Patients who were pathologically diagnosed with pituitary adenoma after surgery were
 recruited, and were able to provide basic information and sign the written informed
 consent form.

 Exclusion Criteria:

 -  The exclusion criteria included claustrophobia, kidney or liver failure, and inability
 to fulfill the study.