Risk Factors Associated With Recurrence and Life-threatening Complications for CSOJ
Risk Factors Associated With Recurrence and Life-threatening Complications for CSOJ
Clinically, recurrence and life-threatening complications are challenging problems for
 chronic suppurative osteomyelitis of the jaw. There is no quantitative analysis or report
 about the causes of or risk factors for the two problems. Doctors identify the causes or risk
 factors only through clinical experience. The investigators performed a retrospective study
 of 322 patients with chronic suppurative osteomyelitis of the jaw. The risk factors for the
 above mentioned two problems were analyzed by logistic regression analysis. The investigators
 found that some of the patients' general conditions, including age, admission temperature,
 admission white blood cell count, pre-admission antibiotic administration without
 consultation, location of the lesion, and general patient condition, were the risk factors.
 The results indicate that doctors should be mindful of those risk factors and that the
 management should be more aggressive when the above risk factors are present.
This is a retrospective study of 322 patients hospitalized with CSOJ. The socio-demographic
 and clinical characteristics were recorded. The risk factors for the above two problems were
 analyzed by logistic regression analysis. Frequency and percentage were used to indicate
 descriptive research factors. A univariate logistic regression analysis was performed to
 calculate the odds ratio (OR) and to identify preliminary risk factors. The preliminary risk
 factors were further identified by multivariate logistic regression analysis.
Inclusion Criteria:

 -  The diagnosis on admission was made on the basis of the presence of sequestra and
 laminations of periosteal new bone in the pathological area.

 -  The other diagnostic criteria is that symptoms such as local pain, pyorrhea, fever,
 swelling, fistula, neuropalsy, odontoseisis, lymphadenopathy, bromopnea, and trismus
 pain are unresponsive or insensitive to conservative therapy and simple debridement.

 Exclusion Criteria:

 -  Patients without confirmed evidence of CSOJ and (or) without standard treatment (a
 combination of antimicrobial therapy and surgery consisting of incision and drainage,
 debridement or sequestrectomy) were excluded.

 -  Paget's disease, hypercementosis, fibrous dysplasia, and early stage malignant bone
 tumor were differentially diagnosed and excluded.