Entral Feeding in Acute Severe Pancreatitis
Entral Feeding in Acute Severe Pancreatitis
• A total of 60 patients admitted to King Abdulaziz Specialists Hospital between June 2018
 and April 2020 with both a clinical and biochemical presentation of acute pancreatitis with
 the following inclusion criteria: Abdominal pain > 6 on the visual analogue scale without
 given analgesia , abdominal distension and tenderness with serum amylase and serum lipase at
 least 3 times the upper limit of the reference range (considering normal lipase level from
 0-160 U/L, and normal amylase level from 0-100 U/L) with confirmed abdominal computerized
 axial tomography of grade D and E on Ranson and colleagues criteria(28) of inflamed
 pancreatic picture.
-  The study was conducted on monitoring of four pillar for 13 days (data collected one day
 before feeding and every three days for 12 days). the first pillar comparing the effect
 of the two enteral feeding methods on the clinical condition of the acute severe
 pancreatitis and this monitored clinically and laboratory by fixed parameters,
 clinically, by abdominal pain which assessed by visual analogue scale (VAS). and
 laboratory, by both markers of severity of pancreatic acini destruction which assessed
 by serum amylase, lipase and Markers of severity of interstitial pancreatic tissue
 destruction which assessed by the level of Lactate Dehydrogenase level (LDH), Aspartate
 aminotransferase (AST), C-reactive protein, prostacyclin and interleukin 8. The second
 pillar include effect of the two enteral feeding methods on the patient's tolerance and
 these monitored in our study by both post-feeding vomiting and post feeding attacks of
 osmotic diarrhea and also abdominal pain. Third pillar include effect of the two enteral
 feeding methods on the patient's general condition and these monitored by follows the
 APACHE II Score, hemodynamics of the patients in both groups (Mean arterial blood
 pressure and pulse) and arterial oxygen saturation (Spo2). Fourth pillar include effect
 of the two enteral feeding methods on achieving satisfactory nutrition parameters of the
 patients and both albumin level, radium blood sugar and electrolytes (sodium and
 potassium level) used as indicator for this.

 -  All parameters observed one day before starting feeding and every 3 days for 12 days
 (duration of the study).
Inclusion Criteria:

 -  acute pancreatitis

 Exclusion Criteria:

 -  systemic disease as hypertension or diabetes