Prediction of Incidence of Liver Cancer by Use of Real-time Tissue Elastography
Prediction of Incidence of Liver Cancer by Use of Real-time Tissue Elastography
This is a multi-center cohort study in which the Real-time Tissue Elastography® measurements
 will predict prospectively the incidence of hepatocellular carcinoma, the incidence and
 severity of gastroesophageal varices ascites and decompensated cirrhosis in hepatitis B or C
 patients.
The aim of this study is to validate the predictive value of Real-time Tissue Elastography®
 by comparison with serum marker or FibroScan® in chronic hepatitis B or C patients.

 Every year and for three years, we performed Real-time Tissue Elastography®, blood sampling,
 gastrointestinal endoscopy. If in the hospital they can perform FibroScan®, FobroScan® also
 be performed.

 Subjects were also performed ultrasonography (US), computed sonography (CT) or magnetic
 resonance imaging (MRI) evry four or six months.

 The time between the Real-time Tissue Elastography®, blood sampling, gastrointestinal
 endoscopy and FiroScan® must not exceed four weeks.
Inclusion Criteria:

 -  Male or female and at least 20 years of age

 -  Chronic hepatitis B or Chronic hepatitis C

 Exclusion Criteria:

 -  Evidence or history of hepatocellular carcinoma

 -  History of alcohol abuse (alcohol intake > 20g/day)

 -  Pregnant or lactating patients

 -  Psychosis