Prophylactic Central Neck Dissection for Papillary Thyroid Cancer
Prophylactic Central Neck Dissection for Papillary Thyroid Cancer
The purpose of this study is to determine whether prophylactic central neck dissection is
 beneficial for patients with papillary thyroid cancer staged preoperatively as node negative.
Several respected organizations have recently recommended that total thyroidectomy plus
 prophylactic central neck dissection should be the standard operation for papillary thyroid
 cancer. However, it is still unclear if this approach has any benefit on survival or
 locoregional control of the disease. In addition, potential advantages of this more
 aggressive surgical approach should outweigh the risk of morbidity. The purpose of this
 retrospective cohort study is to determine whether prophylactic central neck dissection is
 beneficial for patients with papillary thyroid cancer staged preoperatively as node negative.
 In this study outcomes of total thyroidectomy versus this plus prophylactic central neck
 dissection for papillary thyroid cancer are compared in a 10-year follow-up. Patients
 operated between 1993 and 1997 (n=282) underwent total thyroidectomy alone, whereas patients
 operated between 1998 and 2002 (n=358) underwent total thyroidectomy plus prophylactic
 central neck dissection.
Inclusion Criteria:

 -  a pathological diagnosis of papillary thyroid cancer,

 -  in a patient with negative cervical lymph nodes on pre-, or intraoperative evaluation

 Exclusion Criteria:

 -  incidental diagnosis of papillary thyroid cancer following hemithyroidectomy and
 requiring completion thyroidectomy,

 -  one-stage lymph nodes dissection based on therapeutic intent,

 -  previous thyroid surgery,

 -  incomplete follow-up information,

 -  incomplete histopathology report,

 -  ASA grade higher than 3 (American Society of Anesthesiology)