Cardiac Amyloidosis : Diagnostic Using Red Flag Signals
Cardiac Amyloidosis : Diagnostic Using Red Flag Signals
Cardiac amyloidosis is an increasingly contributor of degenerative cardiac diseases. However,
 its frequency remains underestimated, and diagnosis is often realized at late stages of the
 disease. A larger use of clinical and echographic Red Flag signals during routine
 echocardiographic examination may enhance the identification of early stage of the disease.
The objective is to evaluate the clinical and epidemiological aspects of cardiac amyloidosis
 using a systematic screening of even moderate left ventricular hypertrophy, taking into
 account the presence of Red Flag signals. Red Flag Signals will include history or symptoms
 of carpal tunnel syndrome, hearing loss, chronic gastrointestinal disorders, heart failure,
 cervical or lumbar stenosis, or echographic abnormalities such as apical sparring, increased
 left ventricular filling pressure, atrio-ventricular block.
Inclusion Criteria:

 1. Diagnosis of left ventricular hypertrophy defined by a parietal thickness
 (interventricular septum or posterior wall) ≥ 12 mm on the echocardiogram

 2. Age equal or greater than 45 years

 3. Current residency in Martinique, Guadeloupe or French Guyana

 4. Ability to receive and understand research information

 5. Ability to freely deliver informed written consent

 Exclusion Criteria:

 1. Pregnant or breastfeeding woman

 2. Severe uncontrolled hypertension

 3. Chronic hemodialysis

 4. Person under legal protection measures (guardianship, curatorship, safeguard of
 justice), and person deprived of liberty