The Status of Parathyroid Hormone Secretion in Covid-19 Patients
The Status of Parathyroid Hormone Secretion in Covid-19 Patients
COVID-19 infection causes a hypersensitive immune reaction and widespread inflammation in
 various organs of the body, especially through cytokines in the lungs. This cytokine-mediated
 widespread inflammation can also affect the parathyroid glands, resulting in impaired
 parathyroid secretion.

 Researchers evaluated the levels of parathyroid hormone, calcium, phosphorus, and alkaline
 phosphatase in patients hospitalized for COVID-19 infection. Researchers excluded patients on
 intensive care therapy and patients with known parathyroid disease.

 The researchers examined the association of parathyroid hormone secretion with COVID-19
 disease, white blood cells, neutrophil / lymphocyte ratio, C reactive protein, fibrinogen,
 procalcitonin, ferritin, and D-dimer in these patients. The researchers compared the
 parathyroid hormone level of healthy people without COVID-19 infection and known parathyroid
 disease with the parathyroid hormone level of Covid-19 patients.
The coronavirus-2 (SARS-COV-2) virus, which can cause severe acute respiratory syndrome
 through the droplet, has caused the global Coronavirus 19 (COVID-19) pandemic. COVID-19
 infection can be asymptomatic or lead to serious illness and even death. This virus causes a
 hypersensitive immune reaction and varying degrees of widespread inflammation through
 cytokines in various organs of the body, mainly the lungs.

 Cytokine-mediated widespread inflammation caused by the virus may also affect the parathyroid
 glands, causing their functions to deteriorate. Thus, it may cause changes in parathyroid
 hormone secretion.

 The researchers evaluated the results of serum parathyroid hormone, calcium, phosphorus,
 alkaline phosphatase tests in patients who were symptomatic and hospitalized with COVID-19
 infection. Participants also evaluated the relationship of parathormone with white blood
 cells, neutrophil / lymphocyte ratio, c reactive protein, fibrinogen, procalcitonin,
 ferritin, and D-dimer in these patients. The researchers compared the parathyroid hormone
 levels of patients with COVID-19 infection with the parathyroid hormone levels of healthy
 individuals without COVID-19 infection and parathyroid disease. So the investigators looked
 for differences in parathyroid hormone levels between both groups. Researchers did not
 include patients in the intensive care unit and patients with known parathyroid disease.
Inclusion Criteria:

 -  To accept research.

 -  Being over the age of 18.

 -  COVID 19 test results to be positive.

 -  Not taking parathyroid disease medication before.

 -  Receiving inpatient treatment in the COVID service in the hospital.

 Exclusion Criteria:

 -  Not accepting research.

 -  Be under the age of 18.

 -  Negative COVID 19 test results for patients.

 -  COVID patients treated as outpatient.

 -  Parathyroid disease in the healthy control group.