Clinical Trial of CBASP for Individuals With Co-occurring Chronic Depression and Alcohol Dependence
Clinical Trial of CBASP for Individuals With Co-occurring Chronic Depression and Alcohol Dependence
This study examines the effectiveness of Cognitive Behavioral Analysis System of
 Psychotherapy (CBASP) in reducing both alcohol consumption and depressive symptoms in adults
 who are chronically depressed and alcohol dependent.
This study examines the effectiveness of Cognitive Behavioral Analysis System of
 Psychotherapy (CBASP) in reducing both alcohol consumption and depressive symptoms in adults
 who are chronically depressed and alcohol dependent. Participants will receive a 20-session
 course of CBASP psychotherapy over a period of 21 weeks and will be assessed for severity of
 pretreatment psychological abuse and trauma as well as pre and posttreatment interpersonal
 functioning. Two primary hypotheses are to be tested: 1) demonstrate that CBASP is effective
 in reducing depressive symptoms (Hamilton Rating Scale for Depression-24 ratings) and alcohol
 consumption (drinks per drinking day) in this chronically depressed alcohol dependent cohort
 when posttreatment ratings are compared to pretreatment levels; and 2) demonstrate that
 acquisition of feeling safe with the therapist and acquisition of the ability to perceive the
 interpersonal consequences of one's behavior will significantly increase from pre to
 posttreatment levels and will be associated with reductions in drinking and depressive
 symptoms.
Inclusion Criteria:

 -  Clinical diagnosis of a current major depressive disorder (e.g., Major Depression,
 Dysthymic Disorder) for a minimum of two years

 -  Clinical diagnosis of alcohol dependence during the last thirty days

 -  Interest in changing one's drinking and alleviating depressive symptoms

 Exclusion Criteria:

 -  Please call study site for additional information