Neonatal Thrombocytopenia Among Newborns Admitted to Neonatal Intensive Care Unit
Neonatal Thrombocytopenia Among Newborns Admitted to Neonatal Intensive Care Unit
Thrombocytopenia is diagnosed when platelet count is lower than 150,000 U/L, it is a common
 hemostatic problem in neonatal intensive care units According to platelets count, it is
 classified into mild thrombocytopenia with platelet count 100,000 to 150,000 U/L, moderate
 thrombocytopenia with platelet count 50,000 to 100,000 U/L and severe thrombocytopenia that
 have platelet count less than or equal to 50,000 U/L.
Platelets are seen under microscope as small anucleated fragments of megakaryocytes that
 circulate in the blood as discs with an average volume of about 7.5 fimtolitre , 14 times
 smaller than erythrocytes. Platelets count in premature infant is slightly lower than that of
 healthy term infant but is still within the normal range (150,000 to 450,000 unit/ litre ).

 The most common risk factors for thrombocytopenia are

 1. Sepsis: Thrombocytopenia is a frequent problem in neonatal sepsis and is among the most
 predictive, independent risk factors for sepsis-associated mortality

 2. Low birth weight: It is recorded that thrombocytopenia was more common among the
 smallest patients; 85% incidence among those ⩽800 gram, 60% among those 801 to 900 gram,
 and 53% among those 901 to 1000 gram

 3. Perinatal asphyxia: Thrombocytopenia occurred in 31% of neonates with asphyxia versus 5%
 of matched non asphyxiated controls admitted to a neonatal intensive care unit

 4. Prematurity: In a normal pregnancy, the fetal platelet count reaches adult levels
 (150-450 × 106/ millilitre) by the second trimester of pregnancy. Thrombocytopenia ,
 defined as less than 150,000/ millilitre, occurs in 18 to 40% of all preterm neonates
 (gestational age <37 weeks) admitted to neonatal intensive care units
Inclusion Criteria:

 1. newborn (term and preterm, inborn or out born) aged from 1-28 day

 2. platelet count below one hundred and fifty thousands unit/liter

 Exclusion Criteria:

 1. Infant above 28 days old.

 2. Newborns have platelet count one hundred and fifty thousands unit/liter

 Exclusion Criteria: