Exercise in Genetic Cardiovascular Conditions
Exercise in Genetic Cardiovascular Conditions
The goal is to determine how lifestyle and exercise impact the well-being of individuals with
 hypertrophic cardiomyopathy (HCM) and long QT syndrome (LQTS).

 Ancillary study Aim: To understand how the coronavirus epidemic is impacting psychological
 health and quality of life in the LIVE population
Yale is the central site for this multicenter study. Patients with HCM and LQTS will be
 recruited via high-volume HCM and LQTS sites, patient-groups, and websites. Information about
 exercise participation will be acquired via interview and online instruments at enrollment
 and every six months for three years. Quality of Life questionnaires will be filled out at
 enrollment and at the end of the study. Participants will receive a Fitbit (pedometer) and
 will wear it initially for two weeks and then one week every three months. The Fitbit is used
 for assessment of exercise level only. Clinical records will be obtained from treating
 physicians. Participants will also be asked to call the central site if they experience
 syncope, appropriate ICD (implantable cardioverter defibrillator) shock, or resuscitated
 arrest. Information regarding the patient's activity at the time of event will then be
 obtained by phone interview. Follow-up clinical records will be obtained as indicated to
 corroborate endpoints.

 The Ancillary study is optional. This will include all of the baseline questionnaires,as well
 as selected questions from the Epi-Pandemic Impacts Inventory.
Inclusion Criteria:

 -  Individuals with Hypertrophic Cardiomyopathy or Long QT Syndrome

 Exclusion Criteria:

 -  Individuals with Hypertrophic Cardiomyopathy with systolic or diastolic heart failure
 which precludes vigorous exercise will not be enrolled (NYHA III/IV)