Efficacy And Safety Of Parecoxib 40mg vs. Ketoprofen 100mg In The Management Of Acute Renal Colic
Efficacy And Safety Of Parecoxib 40mg vs. Ketoprofen 100mg In The Management Of Acute Renal Colic
This is a multicenter, randomized, double blind, double dummy, comparative, active-controlled
 trial designed to assess the analgesic activity and safety of intravenous doses of parecoxib
 40 mg relative to intravenous doses of ketoprofen 100 mg for the treatment of renal colic in
 outpatients presenting at emergency room settings. This trial is designed to show
 non-inferiority of parecoxib related to ketoprofen.
Inclusion Criteria:

 -  Patient male or female with a confirmed diagnosis of acute renal colic with moderate
 to severe pain according to the VAS and Categoric pain scales

 Exclusion Criteria:

 -  The patient has significant renal or hepatic conditions other than uncomplicated
 kidney stones.

 -  The patient has a history of clinically significant hypersensitivity to any NSAIDs,
 cyclooxygenase inhibitors, analgesics or sulfa medications which has a cross
 sensitivity to the medications used in this study.