Translation, Cross-cultural Adaptation and Validation of the MGQOL-15-F
Translation, Cross-cultural Adaptation and Validation of the MGQOL-15-F
The purpose of this study is to translate and culturally adapt the MGQOL-15 (health-related
 quality of life scale for myasthenia gravis) for use with French-speaking patients in France
 and to evaluate its psychometric properties to ensure reliability and validity.
It is a translation and validation of a quality of life scale.

 Step 1: Translation and cultural adaptation (Forward and back translation, committee review,
 pre-testing with 10 patients for content and face validity).

 Step 2 : Psychometric testing : Test-retest with a 2 day interval, correlation with clinical
 scores - the Myasthenic Muscle Score and the (MG-ADL) score and with a global quality of life
 score (WHOQOL-BREF).
Inclusion Criteria:

 -  Auto-immune myasthenia gravis

 -  Age ≥ 18 years old

 -  Clinical Classification (MGFA) I-IV

 -  French speaking

 Exclusion Criteria:

 -  cognitive or visual impairment which would limit the capacity to fill out the
 MGQOL-15-F