Biology of Thymic Tumors
Biology of Thymic Tumors
This is a retrospective analysis of biological characteristics of thymoma and thymic
 carcinoma patients.
The aim of the present study is to investigated the genetic alterations in tumor samples of a
 series of all WHO-defined subtypes of thymoma patients using high resolution microarray-
 comparative genomic hybridization (CGH) followed by hierarchical cluster analyses of the data
 to identify specific patterns of genetic aberrations and genes associated with each subtype.
 Moreover, tumor samples will be also investigated for some specific potential therapy targets
 by immunoistichemistry, mutation analysis, and fluorescence in situ hybridization (FISH)
 analysis. All these biological data will be correlated with clinical patients characteristics
 and survival data.
Inclusion Criteria:

 -  Availability of tumor tissue and patients with thymoma and thymic carcinoma

 Exclusion Criteria:

 -  NON Availability of tumor tissue and patients with thymoma and thymic carcinoma