Sleep Apnea, Obesity and Pregnancy
Sleep Apnea, Obesity and Pregnancy
Main objective:

 Determine the prevalence of obstructive sleep apnea syndrome (OSA) in late pregnancy in a
 population of obese patients .

 Secondary objectives :

 -  Identify risk factors for OSA during pregnancy (age, parity, high blood pressure,
 snoring , weight, neck circumference, scores on symptoms of sleep apnea, ... ) .

 -  Compare perinatal morbidity among obese patients with OSA in late pregnancy with
 case-controls.

 -  Evaluate the evolution of a moderate or severe OSA 6 months after pregnancy.

 Material and methods

 Characteristics of the study:

 -  Interventional biomedical research

 -  Prospective Multicenter nonrandomized study

 Flow chart

 -  Patients will be included between 30 and 36 weeks of amenorrhea (WA) .

 -  Will rated from inclusion: age, parity, weight, height, BMI in early pregnancy, neck
 circumferrence, treated high blood pressure.

 -  As recommended in France, the main test results during the pregnancy follow-up will be
 recorded.

 -  At the inclusion visit will be conducted a Berlin Questionnaire and Epworth Score.

 -  Screening for OSA by nocturnal polysomnography will be performed between 30 and 36WA.
 This screening can be performed as an outpatient.

 -  In case of proven OSA patients will be offered an appropriate care by today's standards.

 -  Whatever the outcome of pregnancy, a second polysomnography will be performed 6 months
 after childbirth in case of OSA during pregnancy.
Inclusion Criteria:

 -  BMI >35

 -  Pregnancy after 30 Weeks of amenorhea

 -  Age > 18

 -  Signed consentment

 -  Nationnal Health Program affiliation

 Exclusion Criteria:

 -  Twin or more pregnancy

 -  Imprecise term

 -  Artificial insemination with donor gametes

 -  Proved thrombophilia

 -  chronic renal failure

 -  Previously treated (with CPAP) obstructive sleep apnea syndrom