Farming and Movement Evaluation Study (FAME)
Farming and Movement Evaluation Study (FAME)
The long term goal of this research is to elucidate the cause(s) of Parkinson's disease, with
 a focus on environmental determinants. We propose to investigate the relationship between
 Parkinson's disease and exposure to pesticides and other factors by conducting a nested
 case-control study in the Agricultural Health Study.
The long term goal of this research is to elucidate the cause(s) of Parkinson's disease, with
 a focus on environmental determinants. We propose to investigate the relationship between
 Parkinson's disease and exposure to pesticides and other factors by conducting a nested
 case-control study in the Agricultural Health Study.

 The Agricultural Health Study is a cohort study of 52,000 licensed pesticide applicators and
 32,000 of their spouses, conducted in North Carolina and Iowa. It is a joint effort of the
 National Cancer Institute, the National Institute of Environmental Health Sciences, and the
 US Environmental Protection Agency.

 The studies proposed here take full advantage of the Agricultural Health Study. We believe
 that this work could provide a critical and dramatic next step in furthering our knowledge of
 environmental determinants of PD, and thereby take us closer to our goal of finding its
 cause(s)
Inclusion Criteria:

 -  Subjects will be recruited from members of the Agricultural Health Study cohort.