Genetic Polymorphisms of TNF-α Promoter and HBV Genotype on Outcome of HBV-Related Chronic Liver Disease
Genetic Polymorphisms of TNF-α Promoter and HBV Genotype on Outcome of HBV-Related Chronic Liver Disease
The prognosis of Hepatitis B virus (HBV)infection varies from minimal progressive liver
 disease to cirrhosis or hepatocellular carcinoma (HCC).Both viral and host genetic factors
 contribute to disease severity. Cytokine gene polymorphism has been regarded affecting
 prognosis of disease. By detecting HBV genotyping and tumor necrosis factor-alpha
 polymorphism, this study aime to assess their effects and interaction on disease severity of
 HBV-related chronic liver disease and HCC.
Inclusion Criteria:

 -  HBV-positive patients

 Exclusion Criteria:

 -  HBV-negative patients