Investigation of Kritech Efficacy on Subjects Having Functional Discomfort Associated to Joints and Muscles Disorders
Investigation of Kritech Efficacy on Subjects Having Functional Discomfort Associated to Joints and Muscles Disorders
Joints and muscles disorders are common symptoms in the population. They are characterized by
 swelling, pain, functional impairment and morning stiffness. These disorders can be really
 disabling and painful, affecting the person's quality life. The purpose of this clinical
 trial is to test Kritech (Krill oil) efficacy in reducing these symptoms in 154 subjects
 complaining functional discomfort associated to joints and muscles disorders.
Epidemiological studies on prevalence and incidence of joints and muscles disorders are
 scares. Two epidemiological French studies recorded patients consulting their GP for
 widespread pain, whatever the cause. The most often cited pain localization was the
 musculoskeletal system (36-59% of the cases). In Europe the situation is similar, with
 arthritis and osteoarthritis representing the 42% of pains. According to the WHO (World
 Health Organization) the musculoskeletal system's disorders are the first cause of handicap
 in the worldwide population.

 Krill oil is low in both saturated fatty acids and monounsaturated fatty acid and high in
 polyunsaturated fatty acid including a high proportion of (n-3) fatty acids and particularly
 EPA and DHA. There are strong evidences that krill oil may improve the comfort of sensitive
 joints thank to its n-3 fatty acids and phospholipids content. Particularly, after a
 supplementation with a dietary product containing pure krill oil, a reduction of systemic
 inflammation, trough reduction of CRP, was concomitantly accompanied by improvement of
 various clinical scores associated with joint flexibility, comfort and function. Despite
 this, there are no studies yet on healthy volunteers complaining the symptoms of
 rheumatologic pathologies, without being ill.

 Here we performed a clinical trial on 154 subjects complaining functional discomfort
 associated to joints and muscles disorders. The principal objective was to test Kritech
 efficacy in reducing these symptoms.

 Subjects were split in two groups, with one receiving Kritech and the second one the placebo
 for 12 weeks.
Inclusion Criteria:

 -  Male and female subjects;

 -  >18 years old;

 -  Complaining functional discomfort associated to joints and/or muscles disorders,
 motility disorders and/or initial SMFA score higher or equal to 15 ;

 -  Able to give a written or verbal informed consent,

 -  Affiliated or beneficiary of social security

 Exclusion Criteria:

 -  IMC>30kg/m

 -  Acute or chronic, progressive joint disorders (arthrosis, rheumatoid arthritis, acute
 articular rheumatism) of first or second degree and correlated treatments;

 -  Subjects refusing of giving their written or verbal informed consent

 -  Subjects deprived of freedom following an administrative or judicial decision

 -  Participation to another clinical trial in the last four weeks;

 -  People who already participated to another research that comprises an exclusion period
 still ongoing at the time of inclusion