Intervention Facilitates Oral Feeding in Premature Infants
Intervention Facilitates Oral Feeding in Premature Infants
Skin-to-skin combined with breastfeeding shortened the cycle of full-oral feeding in
 premature infants
This study is conducted at the level 3 NICU of the Children's Hospital of Fudan University,
 Shanghai, People's Republic of China, a tertiary medical center. Infants admitted to the NICU
 are all outborn infants.

 The study is approved by the Ethics Committee of the Children's Hospital of Fudan University.
 Signed parental consent is obtained before participants'entry into the study. The RCT is
 conducted to evaluate the effectiveness of skin-to-skin combined with breastfeeding reduce
 the transition time from tube feeding to independent oral feeding.

 The recruited infants are assigned to intervention group and control group.

 Data are presented as means ± sds for continuous variables with normal distribution and
 percentages (%) for categorical variables. One-way analysis of variance and Fisher exact test
 is used to compare infants' baseline characteristics among the two groups. All statistical
 analyses are conducted using SPSS. A p value of less than 0.05 is regarded as statistically
 significant.
Inclusion Criteria:

 -  gestational age ≤30 weeks

 -  birth weight < 1500g

 -  age of admission <72 hours

 -  no congenital malformation

 Exclusion Criteria:

 -  OI > 40

 -  mother has trouble in communicating