Concentration of Plant Sterols in Serum and Aortic Valve Cusps
Concentration of Plant Sterols in Serum and Aortic Valve Cusps
This study investigates the effect of margarines supplemented with plant sterol esters on
 serum and cardiovascular tissue concentrations of plant sterols. We assume that consumption
 of margarine supplemented with plant sterol esters increases serum and cardiovascular tissue
 concentrations of plant sterols (sitosterol; campesterol).
The role of plant sterols in cardiovascular diseases is controversially debated. There is an
 increasing body of evidence that indicates that increased plant sterol serum concentrations
 are correlated with an increased cardiovascular risk. Functional foods such as margarines
 supplemented with plant sterol esters are advertised to patients with hypercholesterolemia.
 Numerous studies show that margarines supplemented with plant sterol esters reduce serum
 cholesterol concentrations significantly. However, there are no studies available
 investigating relevant clinical endpoints. Nor are there any studies availabe investigating
 the effect of the consumption of margarines supplemented with plant sterol esters on serum
 and cardiovascular tissue concentrations. This study is done to investigate the effect of
 margarines supplemented with plant sterol esters on serum and cardiovascular tissue
 concentrations.
Inclusion Criteria: aortic valve stenosis -

 Exclusion Criteria:familial hypercholesterolemia.

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