Efficacy of Trial-Based Cognitive Therapy and Behavioral Activation in Treatment of Depression
Efficacy of Trial-Based Cognitive Therapy and Behavioral Activation in Treatment of Depression
Major Depressive Disorder (MDD) is a mood disorder, highly prevalent in Brazil and in world.
 The treatments of choice are the psychotropic drugs of the class of antidepressants and
 Behavioral or Cognitive Behavior Therapy (CBT). The aim of this study is to compare the
 efficacy of Trial Based Cognitive Therapy with the Behavioral Activation and pharmacotherapy
 in the treatment of MDD in a randomized clinical trial witch 96 patients with MDD,
Major Depressive Disorder (MDD) is a mood disorder, highly prevalent in Brazil and in world.
 MDD is associated with an impaired quality of life and socio occupational functions. The
 treatments of choice are the psychotropic drugs of the class of antidepressants and Cognitive
 Behavior Therapy (CBT). Some of the patients with pharmacotherapy alone still symptomatic.
 This explains the association between psychotherapy and pharmacotherapy. The CBT seek to
 modify thoughts, emotions and behaviors and have shown efficacy in several mental disorders,
 including MDD. Among the CBT models, there is an emphasis on interventions that emphasize: 1)
 the modification or restructuring of thoughts and beliefs. In this point, the Trial based
 cognitive Therapy (TBCP) is an approach with a particular emphasis on the modification of
 core beliefs ; 2) the direct modification of behavior, such as the behavioral activation (BA)
 that analyzes contingencies and encourages the implementation of activities to improve mood.
 This project aims to compare the efficacy of TBCP with the BA in the treatment of MDD. For
 this, a randomized clinical trial will be conducted to treat 96 patients with MDD who are in
 drug treatment, which will be drawn to the interventions of TBCP most psychiatric drugs, BA
 more psychiatric drugs or pharmacotherapy alone, each group with 32 patients. Patients will
 be evaluated with scales and inventories to assess depression, quality of life and social
 functioning, and the data will be statistically compared between groups.
Inclusion Criteria:

 -  Major Depressive Disorder

 -  Both Genres

 -  Minimum of 20 in BDI Score

 -  Refractory depressive disorder

 Exclusion Criteria:

 -  Bipolar disorder

 -  High risk of suicide

 -  Borderline personality