Impact of Sleep Apnea on Sepsis Mortality
Impact of Sleep Apnea on Sepsis Mortality
By clinical record review, this retrospective study aims to compare the mortality of sepsis
 patients with versus without obstructive sleep apnea, who were diagnosed and treated in
 Taipei Veterans General Hospital, Taiwan.
This retrospective study aims to compare the mortality of sepsis patients with versus without
 obstructive sleep apnea (OSA). Patients with a diagnosis of sepsis, who had received a prior
 polysomnography at Taipei Veterans General Hospital during Jan. 1, 2001 to May 31, 2017 will
 be enrolled. Obstructive sleep apnea (OSA) is defined by an apnea-hypopnea index at least
 5/hr with compatible symptoms. Their clinical record will be reviewed and data including
 demography, polysomnography and details related to sepsis (source of infection, number of
 organ dysfunction at initial diagnosis of sepsis and survival time) will be collected. The
 start of the survival time (follow-up time) is the date when sepsis is diagnosed. The end of
 the survival time (follow-up time) is the date of death or end of hospitalization (date of
 discharge). Survival analyses will be performed.
Inclusion Criteria:

 1. Patients who received received a polysomnography at Taipei Veterans General Hospital
 during Jan. 1, 2001 to May 31, 2017

 2. Patients who were admitted with a diagnosis of sepsis after the polysomnography

 3. The diagnosis of sepsis fulfilling the clinical criteria

 Exclusion Criteria:

 1. Younger than 20 years

 2. Not compatible with a definition of sepsis

 3. subjects with incomplete data