Fetuin A in Hashimoto Thyroiditis
Fetuin A in Hashimoto Thyroiditis
Fetuin-A levels are reported to be low as a negative acute phase reactant in systemical
 inflammatory situations. Hashimoto thyroiditis is characterized with inflammation. In this
 study, we hypothesised that the serum fetuin A levels could be found to be low due to
 inflammation in patients with Hashimoto thyroiditis
Patients ≥ 20 years of age being followed up at the outpatient clinics of the Internal
 Medicine Department in Medeniyet University Goztepe Training and Research Hospital and
 fulfilling the eligibility criteria will be included in the study. Approval of the local
 ethics committee and informed consent of the participants will be received for the study. The
 study is conducted in accordance with the Declaration of Helsinki. Demographic
 characteristics, concomitant diseases, smoking and alcohol drinking habits, concomitant
 medication usage, anthropometric and biochemistry data of the eligible patients will be
 recorded. Patient group will consist of patients with newly diagnosed Hashimoto thyroiditis
 and the control group will consist of healthy volunteers.

 Groups will be compared according to their demographic, an¬thropometric and biochemistry data
 and serum fetuin-A levels. In order to detect the relationship between the serum fetuin-A
 levels and clinical features, correlation analyses will be done.
Inclusion Criteria:

 -  patients newly diagnosed with Hashimoto thyroiditis

 Exclusion Criteria:

 -  Acute infection

 -  Acute or chronic inflammatory disease

 -  Anti-inflammatory treatment (non-steroidal anti-inflammatory, corticosteroids etc.)

 -  Hypoxic situations (chronic obstructive pulmonary disease etc.)

 -  Severe heart, kidney and liver disease

 -  Pregnancy

 -  Endocrine disorders

 -  Malignancy

 -  Usage of drug that affects thyroid hormone levels