Optimization of Therapeutic Drug Monitoring of Vancomycin in Pediatric Patients With an Implanted Port Catheter
Optimization of Therapeutic Drug Monitoring of Vancomycin in Pediatric Patients With an Implanted Port Catheter
The goal of this study is to verify whether extensive flushing of the port catheter in
 patients with catheter related blood stream infection will lead to correct vancomycin trough
 levels, taken via the port catheter and compared with simultaneously taken peripheral
 samples.
In this study, extensive flushing of the port catheter prior to blood sampling to determine
 vancomycin trough levels, will be compared with normal flushing. To ascertain correctness of
 the trough levels taken via the central catheter, sampling will occur through a peripheral
 catheter simultaneously.

 Flushing will be done with sodium chloride 0.9 % solution.
Inclusion Criteria:

 -  Pediatric patients with a port catheter

 -  Treated with systemic vancomycin and/or vancomycin "lock"

 Exclusion Criteria:

 -  Age > 18 years

 -  Active downgrading of care