Adding Intra-articular Dexmedetomidine to Levobupivacaine for Postoperative Analgesia in Arthroscopic Knee Surgery
Adding Intra-articular Dexmedetomidine to Levobupivacaine for Postoperative Analgesia in Arthroscopic Knee Surgery
The purpose of this study to search efficacy of intra-articular dexmedetomidine addition to
 levobupivacaine for postoperative analgesia in arthroscopic knee surgery.
Patients between 18-65 years and with American Society of Anesthesiologists' (ASA) Physical
 Status class I-II, who were scheduled for arthroscopic knee surgery, were enrolled in a
 randomised comparative clinical trial. Blinding or masking began in the preoperative holding
 unit. Exclusion criteria were psychiatric illness, younger than 18 yo, who has analgesic
 treatment before the surgery and known hypersensitivity to relevant drugs. All patients
 received a standard anaesthetic protocol; ECG, heart rate, non-invasive blood pressure,
 oxygen saturation and temperature were monitored. After preoxygenation, general anaesthesia
 was induced with sodium pentothal 4 to 7 mg/kg, 1 mcg/kg fentanyl and neuromuscular block was
 achieved with rocuronium 0.5 mg/kg and trachea was intubated. Anesthesia was maintained with
 desflurane 6% and 50% oxygen in the medical air.

 Randomised patients were achieved dexmedetomidine and levobupivacaine or levobupivacaine
 intra-articularly 10 minutes before medical tourniquet deaerated.

 Postoperative analgesia was maintained with morphine in patient-controlled analgesia.
 Patients postoperative VAS values and analgesic consumptions were recorded in postoperative
 24 hours.
Inclusion Criteria:

 -  older than 18 yo

 -  scheduled for arthroscopic knee surgery

 Exclusion Criteria:

 -  younger than 18 yo

 -  known allergy relevant drugs

 -  contraindication for general anesthesia