Safety and Efficacy of Mecobalamin Injection in Peripheral Neuropathies Patients (Study JGAZSY091109)
Safety and Efficacy of Mecobalamin Injection in Peripheral Neuropathies Patients (Study JGAZSY091109)
This is an open-label, randomized, multi-center clinical trial to evaluate the safety and
 efficacy in peripheral neuropathies patients treated with Mecobalamin Injection
Inclusion criteria:

 1. Clinical diagnosis of diabetes induced peripheral neuropathy, other peripheral
 neuropathies (Idiopathic, nutritional and metabolic nature of entrapment neuropathy).

 2. Significant spontaneous pain and / or numbness and other symptoms of neuropathy. TSS
 (Total Symptom Score) >=7.5.

 3. Participation in clinical trials voluntarily and signed informed consent form

 Exclusion criteria:

 1. Pregnancy, preparation for pregnancy or breast-feeding women

 2. Peripheral neuropathy caused by drugs, poisoning, cancer or genetic

 3. Alanine aminotransferase (ALT), aspartate aminotransferase (AST): 2.0 times more than
 the upper limit of normal; Creatinine (Cr) 1.5 times above the upper limit of normal.

 4. Serious organ disease or other serious primary disease merger, the mentally ill,
 poorly controlled hypertension (blood pressure more than 150/100 mmHg after using
 antihypertensive drugs)

 5. Diagnosis of patients with diabetic peripheral neuropathy, but has diabetes ketosis,
 ketoacidosis and severe infection within the past two weeks

 6. Bleeding or bleeding tendency in 2 months

 7. Have allergy

 8. Noncompliance or cannot meet those

 9. Participation in other clinical trials in the last 3 months

 10. Participant unsuitable to participate in this test as investigator considering