Effect of a New Oral Contraceptive Pill on Hormone Related Symptoms Such as Pelvic Pain and Headache
Effect of a New Oral Contraceptive Pill on Hormone Related Symptoms Such as Pelvic Pain and Headache
The aim of the present study is to investigate whether women taking a new combined oral
 contraceptive pill (SH T00658ID, estradiol valerate/dienogest) experience fewer hormone
 withdrawal-associated symptoms such as pelvic pain or headache during their monthly cycle
 compared to a commonly used contraceptive pill (Microgynon).
Inclusion Criteria:

 -  Age between 18 and 50 years (inclusive) at visit 1, for smokers up to 35 years
 (inclusive)

 -  Otherwise healthy female subjects requesting contraception and currently using a
 levonorgestrel, gestodene or desogestrel containing oral contraceptive in a 21-day
 regimen and suffering from at least moderate pelvic pain, headache or both defined by
 an average value of >/= 35 mm for the 3 highest values on a visual analogue scale
 during cycle days 22-28.

 -  Normal or clinically insignificant cervical smear not requiring further follow up (or
 a normal result obtained within the last 6 months before screening)

 -  Able to tolerate ibuprofen and willing to use only ibuprofen supplied for the study.

 Exclusion Criteria:

 -  Women with any contraindication for oral contraceptive use