Intraarterial Nitroglycerin Versus Nicardipine and Radial Artery Occlusion
Intraarterial Nitroglycerin Versus Nicardipine and Radial Artery Occlusion
A total of 600 patients undergoing coronary procedures via transradial access using 6F sheath
 were randomized at the end of the procedure to receive either 250-µg nicardipine or 500-µg
 nitroglycerin administered to the radial artery through the radial sheath before sheath
 removal. A continuous patent hemostasis was applied in each patient with the use of an
 oximetry to maintain an oxygen saturation of >95%, measured in the finger of the accessed arm
 until compression device was totally removed. The primary outcome is early RAO which was
 evaluated by color duplex ultrasonography of the accessed arteries at the day after the
 radial procedure. Secondary outcome was the change of blood pressure at 2-3 minutes after
 drug administration. Radial artery angiogram was performed after radial sheath insertion and
 doppler ultrasound of the accesed radial artery was examined at the day after the procedure.
Doppler ultrasound of the accessed artery was performed at the day after the radial procedure
 in all patients. The absence or presence of antegrade flow in the radial artery will be
 examined while compressing the ulnar artery as previously described.

 The internal lumen radial artery diameter was evaluated by doppler ultrasound as the distance
 between the inner walls of the artery by personnel that are blinded to the study protocol.

 Radial artery angiogram was performed soon after radial sheath insertion and the radial
 artery diameter was measured in AP projection in all patients.
Inclusion Criteria:

 -  All patients undergoing transradial catheterization

 Exclusion Criteria:

 -  Systolic blood pressure < 100 mmHg