24-hour Urinary Aldosterone And Endocrine System In Obesity
24-hour Urinary Aldosterone And Endocrine System In Obesity
The study was aimed at investigating the relationship between hormone parameters and urinary
 aldosterone levels in 24h within a cohort of overweight and obesity.
Subjects were enrolled at the first examination whether they were not taking any medication,
 including oral contraceptives or drugs for osteoporosis, and free of significant medical
 illnesses, except obesity. Exclusion criteria were history of endocrinological diseases
 (diabetes mellitus, hypo or hyperthyroidism, hypopituitarism, etc.), chronic inflammatory
 diseases, stable known hypertension, angina pectoris, stroke, transient ischemic attack,
 heart infarction, congenital heart disease, malignancies, chronic inflammatory diseases,
 renal and liver failure, angina pectoris, myocardial infarction, heart failure, congenital
 heart diseases, minor and major stroke, and inherited thrombocytopenias and other major
 malignancies. Subjects were examined by means of the medical history, hormonal, metabolic and
 routine hematochemical parameters. The investigators provided for a clinical baseline
 evaluation that included extemporaneous ambulatory blood pressure (BP) and a physical
 assessment of body weight, Body Mass Index (BMI) and Waist Circumference (WC) as
 anthropometric parameters.
Inclusion Criteria:

 -  Overweight or obesity (BMI> 25 Kg/m2)

 Exclusion Criteria:

 -  Any kind of drug

 -  Hypertension

 -  Endocrine diseases (diabetes mellitus, hypo or hyperthyroidism, hypopituitarism,
 etc.),

 -  Chronic inflammatory diseases

 -  Renal failure

 -  Liver failure

 -  Angina pectoris

 -  Myocardial infarction and heart failure

 -  Genetic heart diseases

 -  Thrombocytopenias