Opiate Use and Biliary Dilation
Opiate Use and Biliary Dilation
We hope to better define the association between opiate use and biliary dilation, which was
 evident in our previous retrospective study. This prospective study including all endoscopic
 ultrasound procedures performed for further evaluation of biliary dilatation in the setting
 of bilirubin <2 mg/dL will enable accurate measurement of common bile duct and pancreatic
 duct diameter using endoscopic ultrasound and identification of other non- obstructive
 factors which may modulate biliary dilation (i.e. age, cholecystectomy status, duration and
 type of opiate used).
We hope to better define the association between opiate use and biliary dilation, which was
 evident in our previous retrospective study. This prospective study including all endoscopic
 ultrasound procedures performed for further evaluation of biliary dilatation in the setting
 of bilirubin <2 mg/dL will enable accurate measurement of common bile duct and pancreatic
 duct diameter using endoscopic ultrasound and identification of other non- obstructive
 factors which may modulate biliary dilation (i.e. age, cholecystectomy status, duration and
 type of opiate used).

 We believe this work will be of great interest to gastroenterologists, as it provides
 additional data for interpretation of isolated common bile duct dilation in asymptomatic
 patients.
Inclusion Criteria:

 1. Referral/consultation for consideration for EUS ± ERCP

 2. Age 18 and older

 3. Evidence of biliary dilation on abdominal imaging without obstructive pattern on liver
 function tests or imaging.

 4. Willing and able to comply with the study procedures and provide written informed
 consent to participate in the study.

 Exclusion Criteria:

 1. Age <18

 2. Potentially vulnerable subjects including, homeless people, pregnant females,
 employees and students.

 3. Participation in another investigational study that may directly or indirectly affect
 the results of this study within 30 days prior to the initial visit

 4. Other biliary process which accounts for patient's abnormal liver function
 studies/imaging (i.e. mass, stone, cirrhosis).