Coronary Artery Plaque Burden in Stable Angina and Non-obstructive Coronary Artery Disease
Coronary Artery Plaque Burden in Stable Angina and Non-obstructive Coronary Artery Disease
Non-obstructive coronary artery disease (CAD), particularly common in women, has been
 associated with impaired quality of life and risk of recurrent hospitalizations. Several
 studies have also demonstrated increased risk of incident acute coronary events and
 mortality.

 The main objective of the project is to assess the association between coronary artery plaque
 features by coronary CT angiography and long term prognosis in a large unselected population
 undergoing CT coronary angiography due to stable angina and suspected myocardial ischemia
 from the Norwegian Registry for Invasive Cardiology (NORIC) diagnosed with non-obstructive
 CAD by coronary CT angiography.
Patients with stable angina and non-obstructive coronary artery disease by CT coronary
 angiography will be selected from the Norwegian Registry of Invasive Cardiology (NORIC). This
 is a national quality control registry run and controlled by the Norwegian Institute of
 Public Health (www.fhi.no). All CT coronary angiograms will be reanalyzed using advanced
 post-processing analysis software to assess coronary artery plaque burden, distribution and
 composition. Through linking with the Norwegian Cardiovascular Disease Registry and the Cause
 of Death Registry (www.fhi.no) we will be able to assess the association between long-term
 prognosis (5 years) and coronary artery plaque features.
Inclusion Criteria:

 -  Stable angina

 -  Non-obstructive coronary artery disease by CT coronary angiography defined as <50%
 stenosis (lumen diameter reduction)

 Exclusion Criteria:

 -  Obstructive coronary artery disease

 -  Unstable angina

 -  Previous myocardial infarction, heart surgery or percutaneous coronary interventions