Validation of a New TSH Test
Validation of a New TSH Test
The aim of this research project, which is realised with the partnership of the enterprise
 Siamed'Xpress (Marseille), is to validate a new TSH diagnostic test in vitro, to allow an
 earlier screening of hypothyroidism. A serum bank will be conserved in the "Centre de
 Biologie Sud" ("Groupement Hospitalier Lyon Sud").

 The serum samples will be assayed locally for the usual medical support to patients and after
 they will be sent to Siamed'Xpress (Marseille), where they will be assayed with the new
 diagnostic test. The results obtained from the two techniques will be compared.

 The validation of this new TSH test represents a major advancement, since it could bring in
 the future to a therapeutic index which will allow clinicians to treat earlier asymptomatic
 patients with subclinical hypothyroidism.
Inclusion Criteria:

 1. Subjects more than 18 years old

 2. Thyroid test planned in the normal health care of patients

 3. Subject who has been informed about "TSH Testing" study with a complete Subject
 Information Sheet and who has signed a consent form

 4. Subject covered by the Health Social System

 Exclusion Criteria:

 1. Subjects with hyperthyroidism (clinical symptoms : weight loss with unaltered
 appetite, palpitations in the absence of cardio-vascular pathology, unusual and recent
 nervousness)

 2. Subject not covered by the Health Social System

 3. Subject who already participates to another clinical research study, which might
 interfere with TSH Testing Study

 4. Pregnant, parturient or breastfeeding mother

 5. Person deprived of freedom by a judicial or administrative decision

 6. Person under a legal guardianship or unable to consent (MMSE score < 20/30 for the
 patients for whom this test has been performed).