Impact of Nimodipine on Sublingual Microcirculation in Patients With Hemorrhage - a Prospective Monocentric Observational Study
Impact of Nimodipine on Sublingual Microcirculation in Patients With Hemorrhage - a Prospective Monocentric Observational Study
Nimodipine can increase Functional Capillary Density (FCD) as a parameter of the sublingual
 microcirculation in patients with subarachnoid hemorrhage (SAH) compared to patients without
 nimodipine.
SAH group - in patients with SAH and documented vasospasms by digital subtraction angiography
 (DSA) of trans-cranial doppler imaging (TCD) of arteria cerebri media nimodipine is indicated
 because it is proven to improve the clinical outcome. The disfunction of cerebral
 microcirculation in rats with SAH has been documented [1-6]. Changes in sublingual
 microcirculation in patients with SAH with documented vasospasms with nimodipine has not been
 described.
Inclusion Criteria:

 -  adulthood

 -  ICU admission

 -  diagnosis of non-traumatic subarachnoid hemorrhage

 Exclusion Criteria:

 -  inherited coagulation disorder

 -  rheumatic disease

 -  microangiopathy

 -  patient of representative refusal