Does Serum Procalcitonin Levels Predict Sepsis in Patients Undergoing Cytoreductive Surgery
Does Serum Procalcitonin Levels Predict Sepsis in Patients Undergoing Cytoreductive Surgery
Serum procalcitonin levels will be considerably higher, for a longer period of time, in
 patients who develop sepsis compared to patients with SIRS or those who have an uncomplicated
 post-surgical recovery. Monitoring of serum procalcitonin trends will allow for an earlier
 diagnosis of, and initiation of treatment for, sepsis compared to current standard ICU
 methods.
Inclusion Criteria:

 -  Female or male person ≥ 18 years of age

 -  Biopsy proven carcinoma

 -  Scheduled for cytoreductive surgery, with or without HIPEC

 -  Eastern Cooperative Oncology Group (ECOG) performance status (PS) = 0, 1, or 2

 -  Able to give informed consent for protocol participation

 Exclusion Criteria:

 -  Participants are not able to understand or provide written informed consent

 -  Pre-operative anti-inflammatory medication use within 72 hours of their baseline blood
 draw

 -  Pre-operative infection treatment with corticosteroids within 72 hours of their
 baseline blood draw

 -  Immunosuppressive illness other than neoplasm

 -  Pregnant or lactating female