The Time of Positive Conversion of Interferon-γ Releasing Assay After Tuberculosis Exposure
The Time of Positive Conversion of Interferon-γ Releasing Assay After Tuberculosis Exposure
The aim is to evaluate the time of positive conversion after exposure to smear positive
 pulmonary tuberculosis (TB) in a platoon of Korean military, a closed communal setting.
In a platoon where TB outbreak occurred, we performed low dose chest CT (LDCT),
 QuantiFERON-TB gold in tube (QFT) and two-step (0, 4weeks) TST for outbreak investigation. We
 perform QFT at 0, 2, 4, 8 and 12 weeks after initial investigation for soldiers with negative
 QFT results, and soldiers with positive QFT and normal LDCT took isoniazid and rifampin for 3
 months as treatment of latent TB.
Inclusion Criteria:

 -  All soldiers who assigned to the military platoon where a tuberculosis outbreak
 occurred

 Exclusion Criteria:

 -  Soldiers who could not complete study or refused the study protocol