Study of Sitagliptin in Older Type 2 Diabetics (0431-047)(COMPLETED)
Study of Sitagliptin in Older Type 2 Diabetics (0431-047)(COMPLETED)
To evaluate the effect of treatment with sitagliptin compared to placebo in elderly patients
 with type 2 diabetes mellitus who have poor glycemic control with diet and exercise.
Inclusion Criteria:

 -  Community dwelling patients 65 years of age or older diagnosed with Type 2 Diabetes
 not controlled with diet and exercise

 -  Patients must have a HbA1c of 7-10% off medication, or as a result of a protocol
 wash-out from oral anti-hyperglycemic agents by the qualifying visit

 Exclusion Criteria:

 -  Patients with type 1 diabetes

 -  History of ketoacidosis or requires insulin use

 -  Alanine aminotransferase / aspartate aminotransferase > 2.5 X ULN, triglycerides > 600
 mg/dL, creatinine clearance < 35 mL/min

 -  Fasting plasma glucose consistently > 260 mg/dL

 -  Poorly controlled hypertension