Body Composition in Systemic Amyloidosis
Body Composition in Systemic Amyloidosis
Malnutrition is a prominent clinical feature of patients affected by systemic immunoglobulin
 light-chain amyloidosis (AL), with a prevalence ranging between 25-50%. Although the
 prognosis predominantly depend on the presence and severity of cardiac involvement, it was
 shown that malnutrition is an independent predictor of survival and quality of life. However,
 the assessment of nutritional status by common indices based on anthropometry is not always
 feasible and accurate due to reduced performance status and/or the presence of fluid
 imbalances (for example edema and ascites). Several recent studies have demonstrated the
 prognostic value of the phase angle. Moreover, the value is supported by its applicability to
 patients who are bedridden or present alterations in the state of hydration.
Inclusion Criteria:

 -  Diagnosis of systemic immunoglobulin light-chain (AL) amyloidosis

 -  Written informed consent

 Exclusion Criteria:

 -  Age <18 years

 -  Ongoing artificial nutrition

 -  Unavailability to planned measurements