A RCT to Compare Early Continence Recovery After RARP With or Without Sustainable Functional Urethral Reconstruction
A RCT to Compare Early Continence Recovery After RARP With or Without Sustainable Functional Urethral Reconstruction
The study is a prospective randomized controlled trail to compare early urinary continence
 recovery after robotic-assisted radical prostatectomy with or without sustainable functional
 urethral reconstruction (SFUR).
Early urinary incontinence has always been a tricky problem for both patients and urologists,
 even though over 90% patients can recover 12 months after operation. Many urologists are
 trying to improve the surgery, but these new technics mainly help locally advanced prostate
 cancer by better preserving Neurovascular Bundles, urethra, external sphincter or other
 periurethral supporting structures. Sustainable functional urethral reconstruction (SFUR) is
 a novel technic which can improve early urinary incontinence for both locally and locally
 advanced prostate cancer, and even for those with high volume prostate by providing adequate
 urethral length with bladder neck tubularization and sustainable periurethral support with
 peritoneal flap. The purpose of this study is to compare early continence recovery, oncologic
 outcomes and postoperative complications after RARP with or without this new technic.
Inclusion Criteria:

 -  ≥40, but ≤75 years old；

 -  Histological confirmed prostate cancer；

 -  Localized or locally advanced prostate cancer；

 -  Presence of urinary continence prior to the procedure;

 -  Informed consent signed;

 Exclusion Criteria:

 -  Metastatic prostate cancer confirmed by ECT, PSMA or whole-body MRI;

 -  Presence of any prostatic surgery(such as transurethral resection, laser therapy,
 microwave therapy, radiofrequency ablation and so on) prior to the procedure;

 -  Radiation therapy of the prostate or pelvis prior to the procedure;

 -  Uncontrolled intercurrent illness that would limit compliance with study requirements;

 -  Any condition that contraindicates a radical prostatectomy;