Opioid-free Anesthesia in Gynecologic Surgery
Opioid-free Anesthesia in Gynecologic Surgery
Post-operative nausea and vomiting (PONV) is common for the patients undergoing laparoscopic
 gynecologic surgery. PONV is a major factor for patient dissatisfaction, delayed patient
 recovery and increased medical expenses. Opioid-reducing anesthetic regimen is known to
 decrease PONV and facilitate early recovery after surgery (ERAS) and has been widely accepted
 recently. In this study, the researchers intend to investigate whether opioid-free anesthesia
 effectively reduces PONV, and whether it is clinically safe and feasible.
Inclusion Criteria:

 -  Patients scheduled for laparoscopic gynecologic surgery (≥90 min) for benign or
 malignant uterine/ovarian disease

 -  Age ≥ 19

 -  ASA (American Society of Anesthesiologists) class I-II

 Exclusion Criteria:

 -  Uncontrolled hypertension

 -  Untreated intracranial aneurysm

 -  Severely impaired renal or hepatic function

 -  Pregnancy

 -  History of hypersensitivity for drugs used in the study

 -  Patients not using NSAID-containing IV PCA (patient controlled analgesia) device
 post-operatively