Impact of Lactate-Containing Vaginal Lubricant on Sexual Dysfunction in Young Breast Cancer Survivors
Impact of Lactate-Containing Vaginal Lubricant on Sexual Dysfunction in Young Breast Cancer Survivors
The purpose of this study is to determine whether lactate-containing vaginal lubricant is
 effective in the treatment of young breast cancer survivors with sexual dysfunction.
Study scheme

 -  study arm: apply lactate-containing lubricants at the time of sexual intercourse and
 before sleep at least 3 times per a week for 8 weeks

 -  control arm: placebo apply

 Outcome measures

 -  Female Sexual function Index (FSFI-20): at 0 wk and at 8 wk

 -  vaginal maturation index: at 0 wk and 8 wk

 -  vaginal pH: at 0 wk and 8 wk
Inclusion Criteria:

 -  breast cancer survivors over 20 years-old

 -  premenopausal at the time of diagnosis

 -  treated with operation and chemotherapy

 -  newly developed dyspareunia after cancer treatment

 Exclusion Criteria:

 -  recent (< 2 months) start or cessation of hormonal treatment (tamoxifen etc.)

 -  depression or other psychological problems

 -  active vaginal infection

 -  evidence of cancer recurrence

 -  previously use of lactate-containing lubricants

 -  other chronic diseases which severely disturb the sexual life