PHANTOM-S: The Pre-Hospital Acute Neurological Therapy and Optimization of Medical Care in Stroke Patients - Study
PHANTOM-S: The Pre-Hospital Acute Neurological Therapy and Optimization of Medical Care in Stroke Patients - Study
The purpose of this prospective study in acute ischemic stroke patients is to compare
 alarm-to-needle time during randomly allocated periods with and without availability of a
 specially staffed ambulance equipped with computed tomography (CT) and point-of care
 diagnostics. The investigators hypothesize that compared to regular care the investigators
 will reduce alarm-to-needle time by a minimum of 20 minutes by implementation of the stroke
 emergency mobile unit.
Time from symptom onset is crucial for the effectiveness of intravenous thrombolysis in acute
 ischemic stroke patients. Many patients receive tissue Plasminogen Activator (tPA) with
 considerable delay. The investigators developed an ambulance equipped with a CT-scanner,
 point-of-care laboratory, teleradiological support and an emergency trained neurologist on
 board. In the Pre-Hospital Acute Neurological Therapy and Optimization of Medical care in
 Stroke patients (PHANTOM-S)-study the investigators aim at a reduction of the current
 alarm-to-needle time by pre-hospital use of tissue Plasminogen Activator in an ambulance.

 The investigators hypothesize that compared to regular care we will reduce alarm-to-needle
 time by a minimum of 20 minutes by implementation of the stroke emergency mobile unit
 (STEMO).

 This is a prospective study comparing randomly allocated periods with and without STEMO
 availability.
Inclusion Criteria:

 -  Patients whose emergency call prompted the suspicion of stroke within 4 hours of
 symptom onset or with undetermined time of onset in the dispatch center

 -  Informed consent for documentation and follow-up provided by patients or legal
 representatives

 Exclusion Criteria:

 -  age < 18 years

 -  pregnancy