Differential Diagnosis of STA-PSV in Thyrotoxicosis
Differential Diagnosis of STA-PSV in Thyrotoxicosis
Aim: Graves's disease and thyroiditis can both characterized with thyrotoxicosis, but their
 clinical outcome and therapy is quiet different. Measurement of iodine uptake is the gold
 standard to differential diagnosis the thyroiditis or Graves's disease. But the iodine uptake
 is limited for its availability in china and easily influenced by medicine or food contained
 iodine.The blood pattern of thyroid CFDS is useful for differentiate the cause of
 thyrotoxicosis.Most previous studies using the descriptive pattern of thyroid CFDS is easily
 varied by operator subjective judgement. This study is focus on the role of peak systolic
 velocity of thyroid superior artery in differential diagnosis of thyrotoxicosis. Methods:
 Patients with thyrotoxicosis symptoms without recent medicine history were enrolled in two
 clinical center. Its thyroid function, iodine uptake , CFDS of thyroid and peak systolic
 velocity of thyroid superior artery is detected. Thyrotoxicosis is defined as TSH level below
 the low value of normal range. Graves disease is defined as the typical symptoms of graves
 disease such as graves ophthalmopathy or increased iodine uptake. Thyroiditis is defined as
 lack of typical symptoms of graves disease or decreased iodine uptake.We use receiver
 operator curve(ROC) to evaluate its diagnosis value
Inclusion Criteria:

 -  newly diagnosed without taking any antithyroid drug or beta receptor blocker with TSH
 level below the lower limits of reference range

 -  is willing to be enrolled

 Exclusion Criteria:

 -  unwilling

 -  taking antithyroid drug or beta receptor blocker

 -  taking foods or medicine rich in iodine in 8 weeks

 -  women with pregnant or lactation