The Efficacy of Melatonin in the Burning Mouth Syndrome
The Efficacy of Melatonin in the Burning Mouth Syndrome
Burning mouth ( BMS) syndrome is the oral disorder characterized by an intraoral burning
 sensation for which no medical or dental cause can be found. The Headache Classification
 Committee of the International Headache Society (IHS) defines (BMS) as an ''intraoral burning
 or dysaesthetic sensation, recurring daily for more than 2 hours per day over more than 3
 months, without clinically evident causative lesions''. (BMS) is a common, chronic problem
 that has a negative impact on quality of life.

 A wide variety of medications have been proposed for treating (BMS) both topical and
 systemic. Unfortunately, no treatment seems to offer assured results. Melatonin is a
 naturally occurring hormone secreted by the pineal gland. It has soporific effects with oral
 administration and is well tolerated. It enhances sleep Melatonin also may help sleep
 disturbances associated with (BMS) ; however, this remains to be proven.
The purpose of this study is to establish whether melatonin can aid in reducing pain improve
 sleep quality in (BMS)
Inclusion Criteria:

 -  Intraoral burning or dysaesthetic sensation, recurring daily for more than 2 hours per
 day over more than 3 months, without clinically evident causative lesions

 Exclusion Criteria:

 -  Previous or current therapy with melatonin

 -  Allergy or hypersensitivity to melatonin

 -  Less than 18 years old.

 -  Pregnant