Serum Tryptase Concentration During General Anaesthesia With Rocuronium
Serum Tryptase Concentration During General Anaesthesia With Rocuronium
Rocuronium is a aminosteroid structured, non-depolarizing neuromuscular blocking agents
 (NMB). Epidemiological data presents that the frequency of hypersensitivity reactions caused
 by rocuronium have been increased. Determinations of serum tryptase concentrations are
 interdisciplinary recommended in diagnosis of its adverse reactions. No studies have been
 performed to explain specific role of rocuronium doses on serum tryptase values. The aim of
 this study was to investigate the potential effect of rocuronium on serum tryptase
 concentrations.
The greatest risk of hypersensitivity occurs during anesthesia for female patients and it is
 connected with the induction phase using skeletal muscle relaxants . Epidemiological data
 presents that the frequency of hypersensitivity reactions caused by rocuronium have been
 increased. Due to the multiple advantages reports of triggering allergic or hypersensitivity
 reactions caused by rocuronium create doubts about the safety of application .
Inclusion Criteria:

 -  ASA 1-2, no allergy and perioperative hypersensitivity reactions during anaesthesia

 Exclusion Criteria:

 -  steroid therapy, allergy in medical history, mastocytosis