Immunopathology of Autoimmune Hemolytic Anemia
Immunopathology of Autoimmune Hemolytic Anemia
Autoimmune hemolytic anemia (AIHA) is an auto-immune disease mediated by specific antibodies
 targeting red blood cells. Its pathogenesis is not completely understood, and the role of T
 cells have been rarely studied.

 The aim of this study is to compare the frequency of circulating T cells, T cell polarization
 and functions, notably regulatory T cells, during warm AIHA by comparison to healthy
 controls.

 The role of treatments, such as steroids, will also be determined in patients with warm AIHA.
Inclusion Criteria:

 -  Patients diagnosed with primary warm Autoimmune Hemolytic Anemia (wAIHA)

 -  Naive of treatment for hemolytic anemia or in relapse

 -  Older than 16

 -  Able to understand written and spoken French

 -  who have provided written informed consent

 -  INCLUSION CRITERIA for CONTROLS

 -  Persons without auto-immune disease, cancer or active infection.

 -  Older than 16

 -  Able to understand written and spoken French

 -  who have provided written informed consent

 Exclusion Criteria:

 -  Cold agglutinin disease

 -  Pregnancy

 -  Persons without national health insurance