The Migraine and Pain Study GeneBank at Scripps Clinic Registry (MAPS)
The Migraine and Pain Study GeneBank at Scripps Clinic Registry (MAPS)
The objective of this study is to obtain blood or saliva samples to define genes for migraine
 and pain diseases.
It is estimated that over one-third of the world's population suffers from persistent or
 recurrent pain. Migraine is highly heritable and the majority of juveniles who suffer from
 the disorder have a mother or father who also have the disease. The blood or saliva samples
 will go through DNA analysis and be sequenced for candidate genes or subjected to
 whole-genome sequencing. By creating a MAPS GeneBank from these patients' blood/saliva
 donations we will ultimately be able to define genes for migraine and pain diseases.
Inclusion Criteria:

 1. Family members (genetic duo or trio), consisting of an adolescent 10 to 18 years of
 age and at least one of their biologic parents willing to be participate in trial

 2. Adolescent and at least 1 biologic parent with Migraine diagnosis confirmed by Dr.
 Christy Jackson

 3. Is reliable, cooperative and willing to comply with all protocol-specified procedures
 and/or sub-study if consented

 4. Able to understand and grant informed consent

 Exclusion Criteria:

 1. Patient has been previously enrolled in the MAP GeneBank at Scripps Clinic Registry

 2. Has a significant chronic medical condition (i.e.chronic meningitis or a secondary
 origin/cause of headache) which, in the investigator's option, may interfere with the
 patient's optimal participation in the study

 3. Treatment with any investigational agents or devices within 30 days preceding
 enrollment in the study

 4. Has undergone ECT within 90 days preceding enrollment in the study