Impact of Remote Ischemic Postconditioning on Autonomic Function in Stroke Patients
Impact of Remote Ischemic Postconditioning on Autonomic Function in Stroke Patients
The purpose of this study is to determine whether remote ischemic postconditioning (RIPostC)
 initiates autonomic nervous system response and affects the prognosis in patients with acute
 ischemic stroke.
Remote ischemic postconditioning (RIPostC) has proven effective in reducing the
 ischemia-reperfusion injury. But the defensive mechanism of RIPostC still unclear. Stroke is
 frequently associated with autonomic dysfunction. Heart rate variability (HRV) represents the
 autonomic nervous system activity.This study aims to investigate whether RIPostC correlates
 with autonomic function and thus predicts prognosis of stroke.
Inclusion Criteria:

 1. Diagnosed as ischemic stroke according to the Chinese guideline of diagnosis and
 treatment of acute ischemic stroke 2010

 2. Age between 18 to 85 years old

 3. initial ischemic stroke within 14 days or less.

 4. National Institutes of Health Stroke Scale (NIHSS)score 0-15

 5. Modified Rankin Scale(mRS)score 1-4

 6. Informed consent

 Exclusion Criteria:

 1. Intravenous or arterial thrombolysis, or revascularization

 2. Acute myocardial infarction,atrial fibrillation,arrhythmia,or cardiogenic cerebral
 embolism

 3. Systolic Blood Pressure(SBP)>200mmHg after medication treatment

 4. Plasma fibrinogen>7g/L

 5. Upper limb fracture or percutaneous injury

 6. Subclavian artery stenosis

 7. With severe cardiac,respiratory,hepatic,and renal dysfunction or malignant tumor

 8. Simultaneous participation in another interventional study

 9. Pregnancy