Single Port Versus Four Ports Laparoscopic Cholecystectomy and Early Postoperative Pain
Single Port Versus Four Ports Laparoscopic Cholecystectomy and Early Postoperative Pain
This is a trial to evaluate if single port laparoscopic cholecystectomy causes less pain than
 conventional laparoscopic cholecystectomy.
This study is a randomized, two-arm, double-blinded three-center trial to compare single-port
 transumbilical laparoscopic cholecystectomy with conventional 4-port laparoscopic
 cholecystectomy. 120 patients are included with a 1:1 randomization. Three centers
 participate in the trial.

 Inclusion criteria: Female patients, ASA I-III, age between 18 and 75 years, elective
 laparoscopic cholecystectomy because of biliary pain or recent uncomplicated biliary
 pancreatitis.

 Exclusion criteria: Expected poor compliance, history of cholecystitis or severe
 pancreatitis, previous open upper abdominal surgery, pregnancy or lactation, preoperative
 chronic pain or conversion from laparoscopic to open surgery.

 Pain and nausea is measured on VAS before the operation and 3 hrs, 1 day, 2 days and 3 days
 after the operation.

 Cosmesis is evaluated after 28 days.

 Patients are telephone-interviewed after 12 months and asked about port hernia formation. If
 hernia is suspected patients are called in for an abdominal ultrasonography.
Inclusion Criteria:

 -  ASA I-III

 -  Planned elective laparoscopic cholecystectomy because of biliary pain or uncomplicated
 biliary pancreatitis

 Exclusion Criteria:

 -  Expected poor compliance

 -  History of cholecystitis or severe pancreatitis

 -  Earlier open upper abdominal surgery, pregnancy or lactation, chronic pain or
 conversion to open surgery