The Effects of Iontophoresis in Women With Gynoid Hidrolipodystrophy.
The Effects of Iontophoresis in Women With Gynoid Hidrolipodystrophy.
Introduction: Gynoid hydrolipodystrophy (HLDG) or cellulitis is a subcutaneous tissue
 disorder, with several strategies for its treatment, such as caffeine and iontophoresis.
 Objective: To evaluate the effects of caffeine-associated iontophoresis for the treatment of
 HLDG. Methods: In a longitudinal study, participants will be evaluated for: photographic
 documentation, ultrasound imaging, thermography and quality of life questionnaire. If
 included, they will be separated into 3 randomized groups (n = 30). G1: use of base gel (n =
 10); G2: use of iontophoresis and gel with caffeine (n = 10) and G3: use of iontophoresis
 alone (n = 10). The groups will be treated with 10 sessions, 2 times per week. After that
 they will be reevaluated. Statistical analysis: The software used will be the SPSS
 StatisticalPackage (IBM SPSS Statistics, Chicago, IL, USA). The data distribution will be
 analyzed by the Shapiro-Wilk test. In case of normal distribution, the data will be described
 as mean ± standard deviation; otherwise, as median [interquartile range 25-75%]. For
 comparison of the data, we will use ANOVA and for comparison of means the Tukey test and case
 not normal distribution, krulskal-Wallis test and the Dunns test. The level of statistical
 significance adopted will be P <0.05. Expected contributions: It is expected that
 investigators can contribute to the treatment of patients with HLDG and analyze the effects
 of iontophoresis with caffeine, both in clinical and scientific practice, providing a method
 that is valid and reliable for this purpose; multidisciplinary training of highly qualified
 human resources and the strengthening and consolidation of a research team.
Inclusion Criteria:

 -  Patients with mild to moderate cellulite diagnosis will be included, according to the
 validated Photonumeric scale of cellulite severity

 -  Body mass index less than 30 (kg / m2)

 Exclusion Criteria:

 -  Individuals who have a deregulated menstrual cycle who are pregnant;

 -  Breastfeeding or using some hormone;

 -  Antibiotic medication including steroids over 1 month of treatment of skin diseases;
 •Sensitivity or hypersensitivity of the skin;

 -  Use of the same or similar cosmetics or remedies on the glutes within 1 month;

 -  Surgical procedure (liposuction and skin treatments) in the region to be treated or
 planning some procedure within the study period;

 -  Chronic debilitating diseases such as asthma, diabetes or hypertension;

 -  Atopic dermatitis