Neuro-ultrasound Assessment in Behcet's Disease
Neuro-ultrasound Assessment in Behcet's Disease
Assessment of structural changes that occur in large extracranial and intracranial arteries
 in patients with Behcet's disease
Patients will be selected from Rheumatology and Rehabilitation inpatient and outpatient
 clinics in Assiute University Hospital Patients under 16 years old, patients with
 hyperlipidemia, hypertension, diabetes mellitus and all other risk factors affecting blood
 vessel intimal thickness will be excluded from the research.

 All patients and control groups underwent a complete extracranial and intracranial ultrasound
 assessment by 2 experienced neurovascular sonographers .The ultrasound examination was done
 at the Neurovascular Ultrasound Laboratory in the Neurology department, Assiut University
 hospitals using a color-coded duplex ultrasound device Philips HD5 (Philips Medical Systems,
 Nederland B.V.) for the carotid and vertebral arteries and for the intracranial arteries.

 Intimal medial thickness (IMT) of the common carotid artery (CCA), peak systolic velocities
 (PSVs) and end diastolic velocities (EDVs) were measured in the common, internal, and
 external carotid arteries (CCA, ICA, ECA) with L 3-12 MHz linear transducer probe and when
 stenosis was detected the velocities were measured at the maximally stenotic area.

 The intracranial arteries were evaluated in all patients with transcranial color-coded
 duplexsonography (TCCS) with the use of a low-frequency (2- to 5-MHz) phased-array probe
 through the transtemporal acoustic bone window. The middle cerebral artery (MCA),
 intracranial segment of vertebral artery (V4)and basilar artery (BA) were examined. Peak
 systolic velocity (PSV) and flow direction (antegrade or reversed) used for the diagnosis of
 any intracranial atherosclerotic disease (ICAD).

 The findings and the atherosclerotic changes in the extracranial and intracranial vessels
 were interpreted according to the internationally published data Data will be analyzed using
 the computer program SPSS
Inclusion Criteria:

 -  patient more than 18 years old

 -  All patients fulfill the modified International Criteria for Behçet's Disease

 Exclusion Criteria:

 -  Patients under 16 years old,

 -  patients with hyperlipidemia, hypertension, diabetes mellitus and all other risk
 factors affecting blood vessel intimal thickness