Bone Status and Insulin Resistance in Hirsutism
Bone Status and Insulin Resistance in Hirsutism
The purpose of this study is to investigate how the bones of hirsute women are different from
 bones of healthy women. The change in hormone content in the blood will also be investigated.
 The study can be used to evaluate whether it will be relevant to bone scan all newly referred
 hirsute women.

 Hirsute women are often over-weight and often have an increased amount of the male sex
 hormone in their blood. Their blood tests often show changes reminding of the ones seen in
 diabetic patients.

 All hirsute women referred to the department will undergo an investigation revealing the
 reason for the increased hair growth. The investigation includes clinical investigation
 (height, weight and degree of hair growth), blood tests (for hormone status and bone status
 analysis) and bone scanning of the abdomen (body composition).

 The trial includes a group of 50 strongly hairy women and a control group of 50 healthy women
 with normal hair growth. They are matched by body weight, since weight has great importance
 for the bone mineral content and thereby for osteoporosis in the long run.
Inclusion Criteria:

 Hirsute subjects:

 -  Belonging to group 1 or 2.

 -  Age: 20-46

 -  Hirsute score: >7

 -  Written informed consent

 Control group:

 -  Age: 20-46

 -  Hirsute score: 0 (without razing)

 -  Regular menses

 -  Written informed consent

 Exclusion Criteria:

 -  Previous cosmetic treatment for hirsutism.

 -  Use of contraceptive pill (within the past 6 months)

 -  Systemic steroid treatment > 6 weeks (ever)

 -  Age above 46 years/post menopause (increased FSH)

 -  Recognized diabetes mellitus or other endocrine disease

 -  Eating disorder

 -  Serious, treatment demanding disease