Effects of Ginger Supplementation on NF-KB in Peripheral Blood Mononuclear Cells in Type 2 Diabetes Mellitus
Effects of Ginger Supplementation on NF-KB in Peripheral Blood Mononuclear Cells in Type 2 Diabetes Mellitus
This study evaluates the effect of ginger on NF-KB level in Peripheral Blood Mononuclear
 Cells in type 2 diabetic patients. Half of patients will receive ginger, while the other half
 will receive placebo.
ginger is a plant with lots of phytochemicals which have antioxidant effects. It reduces the
 NF-KB levels in the cells because of its antioxidant effects. It can reduces insulin
 resistance as a result of NF-KB reduction in diabetes.
Inclusion Criteria:

 -  type 2 of diabetes diagnosed for 1 to 10 years

 -  age 30-60 years

 -  BMI = 18.5-35 kg/m*m

 -  treatment with Metformin or Glibenclamide

 Exclusion Criteria:

 -  Treatment with insulin

 -  Weight loss more than 10% in 6 months

 -  Treatment with TZDs (thiazolidinediones)

 -  Pregnancy and breast feeding

 -  Smoking and alcohol consumption

 -  Multivitamin-mineral and polyphenols and omega-3 and 6 supplementation in the last 3
 months and during study

 -  Ginger supplementation and herbal medicines

 -  Anticoagulation consumption such as heparin and warfarin

 -  NSAIDs such as diclofenac and salicylate drugs such as aspirin, corticosteroids such
 as prednisone consumption during 1 month ago and during the study

 -  Infectious and inflammatory diseases such as rheumatoid arthritis

 -  Impaired hepatic, renal and gastrointestinal function

 -  Cancer

 -  Currently suffering from acute illness that needs medical treatment