A Study to Compare Different Intubating Doses of Zemuron in Pediatric and Adolescent Subjects Under General Anesthesia
A Study to Compare Different Intubating Doses of Zemuron in Pediatric and Adolescent Subjects Under General Anesthesia
The primary purpose of this study is to evaluate the time course of muscle relaxation after
 administration of three different single intravenous bolus doses of rocuronium bromide for
 intubation (insertion of a tube through the nose or mouth into the trachea to provide
 artificial ventilation) in term neonates (birth to <28 days old), infants (28 days to <=3
 months) and toddlers (>3 months to <=2 years), children (2 years to less than or equal to 11
 years of age), and adolescents (>11 years to less than or equal to 17 years of age).

 Subjects in each of the age groups will be randomized to one of 3 Zemuron® doses: 0.45 mg/kg,
 0.6 mg/kg, or 1.0 mg/kg.
Inclusion Criteria:

 -  Male and female subjects from birth up to 17 years of age who will be scheduled for
 surgery under general anesthesia.

 Exclusion Criteria:

 -  Subjects whose parent(s) or legal guardian(s) are not willing to give written consent
 and where applicable, subjects who have not given appropriate assent to participate in
 the trial will not be allowed to enter.