Spectral Dynamic Imaging of Cognitive Functions in Epileptic Patients Explored Stereoelectroencephalography
Spectral Dynamic Imaging of Cognitive Functions in Epileptic Patients Explored Stereoelectroencephalography
This prospective research aims to develop the use of Spectral Imaging in addition Dynamics of
 cortical electrical stimulation to identify major anatomical and functional networks in
 epileptic patients candidates for surgery and explored by stereoencephalography, to minimize
 risk of post-surgical cognitive deficits.
Cognitive deficits after epilepsy surgery are poorly known particularly because the tools
 used to evaluate them. In addition, the prevention of certain postoperative deficits, is
 extremely difficult because of the lack of robust markers to anticipate. The various
 examinations conventionally used for this purpose (neuropsychological testing, functional MRI
 and cortical stimulation) does indeed provide insufficient information or difficult to
 interpret, so the development of improved methods appears as an imperative in the field of
 the epilepsy surgery.

 SID appears as such particularly adapted to the case of epileptic patients explored SEEG to
 provide individualized cognitive map millimeter thereof without requiring, for additional
 invasive act, or risk of inducing unintended crisis. In practice, this clinical research
 project should lead to the definition of several simple cognitive tasks which, together,
 could be achieved by each volunteer patient in two or three hours, and then analyzed in a
 similar time to provide fast, even the patient is still explored SEEG and even before
 cortical electrical stimulation, a list of brain regions involved in most major cognitive
 functions.
Inclusion Criteria:

 -  Drug-resistant partial epilepsy justifying a SEEG exploration

 -  Intellectual capacities compatible with the award of cognitive tasks

 Exclusion Criteria:

 -  Pregnant or lactating women

 -  Patient deprived of liberty by a judicial or administrative

 -  Major patient subject to a measure of legal protection