Gustatory Dysfunction Among a Sample of Depressed Egyptian Adults Under Anti-depressants Therapy
Gustatory Dysfunction Among a Sample of Depressed Egyptian Adults Under Anti-depressants Therapy
- Assess gustatory thresholds among a sample of depressed Egyptian adults (age from 20 to 50
 years old) under anti-depressants therapy ( for at least 3 months) using filter paper
 disc(FPD) method through a scoring system. - Determine the taste intensity at supra-threshold
 among these patients using a psychophysical method through a scoring system. - Identify
 possible modulators for developing gustatory dysfunction among these patients using a
 questionnaire ( appendix) with a binary measuring unit (yes/no).
PECO

 -  P Population: depressed Egyptian adults under anti-depressants therapy

 -  E1 Exposure 1: commonly prescribed tricyclic antidepressants (Imipramine, Amitriptyline,
 Clomipramine HCL)

 -  E2 Exposure 2: commonly prescribed Selective Serotonin Re-uptake inhibitors
 antidepressants ( Fluoxetine, Fluvoxamine, Sertraline, Citalopram, Paroxetine)

 -  C control (non exposure) : non-pharmacological treatment ( psychotherapy)

 -  O Outcome:

 Primary 1ry : Assess gustatory thresholds among a sample of depressed Egyptian adults (age
 from 20 to 50 years old) under anti-depressants therapy ( for at least 3 months) using filter
 paper disc(FPD) method through a scoring system.

 Secondary 2ry: - Determine the taste intensity at supra-threshold among these patients using
 a psychophysical method through a scoring system. - Identify gustatory dysfunction modulators
 among these patients using a questionnaire ( appendix) with a binary measuring unit (yes/no).
Inclusion Criteria:

 -  Depressed Egyptian adults under antidepressants therapy for at least 3
 months/non-pharmacological treatment( psychotherapy)

 -  Age from 20 to 50 years old

 Exclusion Criteria:

 -  Antipsychotics

 -  Hypnotics

 -  Anticonvulsants

 -  Ages other than the mentioned

 -  Olfactory dysfunction

 -  Chemosensory dysfunction