MEP and Neuromuscular Blocker
MEP and Neuromuscular Blocker
It is important to predict the influence of the neuromuscular blocking agents on the motor
 evoked potential. Investigator will investigate the dose-response relationship between the
 degree of the neuromuscular blockade and the motor evoked potential in patients undergoing
 brain tumor surgery using the population approach. Investigator will investigate the
 influence of the other factors such as the impedence, reactance, muscel amount, and age on
 the motor evoked potential.
Inclusion Criteria:

 1. Patients aged 19 years old or older, with American Society of Anesthesiologists Physical
 Status 1-3, and scheduled for elective brain tumor surgery under the monitoring of the
 motor evoked potential

 Exclusion Criteria:

 1. Central or peripheral neuromuscular disease

 2. Sensory or motor nerve disorder

 3. Allergy to propofol, remifentanil, and rocuronium

 4. Patients with pacemaker