Prevention of Levodopa-induced Dyskinesias by Transcranial Static Magnetic Field Stimulation (tSMS)
Prevention of Levodopa-induced Dyskinesias by Transcranial Static Magnetic Field Stimulation (tSMS)
This is a randomized sham-controlled double-blind study to test the hypothesis that
 transcranial static magnetic field stimulation (tSMS) of the motor cortex improves
 levodopa-induced dyskinesias in patients with Parkinson's disease. Half of the patients will
 receive real tSMS treatment, the other half will receive sham treatment (placebo).
Inclusion Criteria:

 -  advanced idiopathic Parkinson's disease (Brain Bank criteria)

 -  optimal clinical response to dopaminergic medication (>30% UPDRS-III improvement)

 -  presence of clinically relevant levodopa-induced peak-dose dyskinesias in at least one
 upper limb

 Exclusion Criteria:

 -  MRI-incompatible metal objects in the body (e.g. cardiac pacemakers)

 -  other main neuropsychiatric co-morbidity