A Modified Lateral Lumbar Interbody Fusion VS. Transforaminal Lumbar Interbody Fusion for Adult Degenerative Scoliosis
A Modified Lateral Lumbar Interbody Fusion VS. Transforaminal Lumbar Interbody Fusion for Adult Degenerative Scoliosis
A modified lateral lumbar interbody fusion VS. transforaminal lumbar interbody fusion for the
 treatment of adult degenerative scoliosis with 2 year follow-up with a multiple center,
 randomized case-control study
Adult degenerative scoliosis (ADS) is the most common spinal deformity in the elderly, and
 the severe patients need surgical treatment. The elderly are often complicated with many
 medical diseases and the perioperative risk is high, so minimally invasive surgery is a new
 choice for spinal surgeons to treat ADS. Modified lateral lumbar interbody fusion (CLIF) is
 an new modified spinal minimally invasive interbody fusion technique in the investigator's
 department. The results of preliminary studies showed that it has the advantages of less
 trauma, short operation time and fewer complications, and the clinical and imaging outcome
 are remarkable. Therefore, the present study aims to establish a multicenter, large sample
 prospective randomized controlled study to explore the technical advantages and surgical
 indications of the new technique in the treatment of ADS by comparing with the traditional
 posterior spinal interbody fusion; (2) to compare the postoperative clinical and imaging
 results and analyze the surgical complications and preventive measures; (3) to establish a
 long-term follow-up to further quantify the clinical and imaging outcome of the new
 technique. Therefore, this study will further verify the safety and effectiveness of the CLIF
 in the treatment of ADS on the basis of previous studies, and provide a new clinical approach
 for minimally invasive treatment of ADS.
Inclusion Criteria:

 -  at least 50 years of age, diagnosed with adult thoracolumbar scoliosis including any
 number of intervertebral levels between T8 and S1, unresponsive to conservative
 treatment for at least 6 months, and had a preoperative coronal Cobb angle of at least
 10° and preoperative ODI score of at least 30%.

 Exclusion Criteria:

 -  with prior lumbar fusion surgery or spondylolisthesis greater than Grade II