Clinical and Microbiologic Characteristics of Cephalosporin-Resistant E. Coli-PITT Protocol
Clinical and Microbiologic Characteristics of Cephalosporin-Resistant E. Coli-PITT Protocol
The purpose of this study is to review patients with E. coli infections at UPMC from
 September 1, 2008 to August 31, 2010 to determine if these infections have arisen in the
 community rather than in hospitals or nursing homes and determine their clinical outcomes.

 The specific aims of this study are to:

 1. Review whether cephalosporin-resistant E. coli infections are hospital-acquired,
 healthcare-associated or community-associated.

 2. Determine the clinical outcome of the patients according to the antibiotics given.
De-identified data will be obtained by the honest broker for the requested time period. In
 addtion, the honest broker will work with the microbiology laboratory to collect the isolates
 associated with the de-identified data. All data and samples will be de-identified.
 De-identified data will be given to the nurse coordinator to complete the case report forms
 and enter the data into the password protected database and the de-identified isolates will
 be stored and analyzed on the 8th floor Scaife in Dr. Yohie Doi's laboratory.
Inclusion Criteria:

 -  patients with E. coli infections at UPMC

 Exclusion Criteria:

 -  not meeting entry criteria