FLU-FIT Program at Kaiser Permanente Northern California
FLU-FIT Program at Kaiser Permanente Northern California
The investigators overall goal is to develop, implement, test, and disseminate an
 intervention to increase colorectal cancer screening rates at Kaiser Permanente (KP) by
 providing home fecal immunochemical test kits (FIT) to eligible patients aged 50 and older
 who participate in annual influenza vaccination campaigns. The investigators hypothesis is
 that the FLU-FIT Program will be an effective method to increase colorectal cancer screening
 rates at Kaiser Permanente.
Background: Colorectal cancer is the second leading cause of cancer death in the U.S. Many of
 these deaths could be prevented by screening, which is recommended for adults aged 50 and
 older. Effective screening options include yearly fecal occult blood tests, flexible
 sigmoidoscopy every 5 years, or colonoscopy every 10 years. Unfortunately, despite these
 recommendations and options, only half of adults aged 50 and older are up to date with any
 test. Simple, cost-effective approaches to increase colorectal cancer screening rates are
 needed to reduce the burden of colorectal cancer in the U.S.

 Objective/Hypothesis: Our hypothesis is that offering annual colorectal cancer screening with
 fecal occult blood tests to eligible adults aged 50 and over during annual nurse-run
 influenza vaccination clinics will result in increased colorectal cancer screening rates,
 reaching populations that have been under-screened in the past. Our overall objective is to
 develop, implement, test, and disseminate this intervention using an annual fecal
 immunochemical test for occult blood (FIT) at Kaiser Permanente (KP) Northern California.

 Specific Aims: The specific aims of this research are to (1) develop and implement a
 comprehensive nurse-run FLU-FIT Program at the KP Santa Clara facility that will systematize
 the offering of FIT to all eligible patients aged 50 to 80 who attend annual influenza
 vaccination clinics; (2) test the effectiveness of the FLU-FIT Program in improving
 colorectal cancer screening rates in the context of a time-randomized, controlled trial
 involving an ethnically diverse population of influenza vaccination clinic attendees at 8
 influenza vaccination sites within 4 other KP Northern California service areas; (3) evaluate
 the reach and robustness of the FLU-FIT Program as implemented within these 8 sites, and (4)
 create a FLU-FIT Program Toolkit that can be used in further efforts to disseminate this
 intervention both within Kaiser Permanente and to other clinical settings.

 Study Design: The study will be conducted in 3 phases. In Phase 1 (Year 1), we will evaluate
 a pilot FLU-FIT Program that is already underway at KP Santa Clara and implement it
 systematically for its annual influenza vaccination clinics in 2009-2010. In Phase 2 (Years 2
 and 3), the key elements of the KP Santa Clara FLU-FIT Program will be tested in a
 time-randomized trial within 8 other KP Northern California sites. On randomly assigned dates
 at each of the 8 influenza vaccination clinic sites, patients will receive either the FLU-FIT
 Program (intervention) or influenza vaccination only (control). The primary outcome will be
 the proportion of intervention subjects between the ages of 50 and 80 who are initially due
 for colorectal cancer screening that become up to date with colorectal screening within 3
 months after receiving their influenza vaccine, as compared to similar subjects in the
 control group. The robustness of the intervention as an effective and sustainable
 intervention to increase rates of colorectal cancer screening in "real world" settings will
 also be evaluated according to the RE-AIM criteria (Reach, Efficacy, Adoption,
 Implementation, and Maintenance). In Phase 3 (Year 4), data will be analyzed, and a toolkit
 for further dissemination activities will be developed.

 Cancer Relevance: If successful and widely implemented, the FLU-FIT Program could increase
 access to colorectal cancer screening for millions of Americans. This approach could also
 provide a model for developing effective cancer screening interventions that do not depend
 solely on the primary care clinician, and that can be triggered by other regular contacts
 that patients have with the healthcare system.
Inclusion Criteria:

 -  Adults aged 50-75 at the time of their flu shots who are also due for colorectal
 cancer screening.

 Exclusion Criteria: none

 -