Migraine Manager (R01)
Migraine Manager (R01)
The objective of this trial is to test whether an online tailored intervention, Migraine
 Manager, is efficacious in improving headache outcomes compared to an attention control
 intervention in adolescents with migraines. We will conduct a randomized clinical trial to
 compare a sample of 80 youth (ages 11 to 17) with migraine receiving the online tailored
 adherence intervention to 80 youth in an attention control group. We will test whether
 adherence to healthy habit (hydration, regular meals, exercise, sleep) recommendations serves
 as a mechanism for improved headache outcomes. Clinically meaningful outcomes will be
 assessed by reliable, valid, and sensitive measures. The primary outcome (i.e., number of
 headache days) will be assessed via online daily diary pre- and post-intervention, with
 additional follow-up at 3, 6, 9, and 12 months. Secondary outcomes include health-related
 quality of life and migraine disability.
Inclusion Criteria:

 -  Confirmed diagnosis of migraine using current International Classification of Headache
 Disorders Criteria (ICHD-3) for migraine with or without aura

 -  Frequency of 8 or more headaches per month

 -  Access to the internet whether public (e.g., library) or private (e.g., home,
 personal)

 -  English fluency for patient and caregiver

 Exclusion Criteria:

 -  Patients with a diagnosis of pervasive developmental disorder as determined by medical
 chart review

 -  Patients with a diagnosis of or serious mental illness (e.g., psychotic disorder) as
 determined by medical chart review