Prospective Study Assessing Emotional, Sexual and Quality of Life Concerns Of Women Undergoing Removal of the Cervix Versus Removal of the Uterus,Ovaries and Fallopian Tubes For Treatment Of Early Stage Cervical Cancer
Prospective Study Assessing Emotional, Sexual and Quality of Life Concerns Of Women Undergoing Removal of the Cervix Versus Removal of the Uterus,Ovaries and Fallopian Tubes For Treatment Of Early Stage Cervical Cancer
The purpose of this study is to will help us understand how two treatments impact women with
 early stage cervical cancer: a radical hysterectomy, which removes the entire uterus, the
 ovaries, and fallopian tubes versus a radical trachelectomy which removes the cervix, which
 is the bottom part of the uterus. The second leaves the rest of the uterus, the ovaries, and
 fallopian tubes. This means that there is a chance that the woman might be able to get
 pregnant in the future with this type of treatment. We believe that these two operations need
 further study to see how they impact women. This study will look at emotions and issues of
 fertility. The study will also ask about quality of life and sexual functioning. What we
 learn from this study will help us give better information to women considering these
 treatments.
This project will prospectively assess and describe the emotional, sexual and quality of life
 impact of radical trachelectomy in comparison to the standard treatment of radical
 hysterectomy in women with early stage cervical cancer over a two year time period. Women
 being considered for radical trachelectomy with laparoscopic pelvic lymphadenectomy or
 radical hysterectomy (abdominal, laparoscopic or schauta) will be approached for study
 participation prior to undergoing surgery. After providing informed consent, participants
 will be given a survey questionnaire pre-operatively and asked to complete follow-up surveys
 post-operatively at follow up medical appointments at 3 months, 6 months, 12 months, 18
 months and 24 months. We will assess the following domains in these women; mood, sexual
 functioning, and quality of life in addition to issues of fertility and treatment choice. The
 survey will take approximately 30 minutes to complete. The findings will be used to provide
 additional information to women considering these procedures and enable future interventions
 to be designed to meet any identified needs. In addition, the findings of this study will
 also be presented for consideration of a multi-center feasibility study.
Inclusion Criteria:

 -  Patients should be suitable surgical candidates and completed the surgical consenting
 process with their gynecologic oncology surgeon.

 -  Confirmed invasive cervical cancer: squamous, adeno, or adenosquamous.

 -  FIGO Stage IA1 with lymph-vascular space involvement or stage IA2-IB2).

 -  Consented for a radical trachelectomy (vaginal/abdominal) or radical hysterectomy
 (laparoscopic/abdominal).

 -  Have not started or completed childbearing.

 -  Strong desire to preserve fertility (trachelectomy group only).

 -  At least 18 years of age and not older than 45 years at the time of treatment.

 -  Able to read/ speak the English language.

 -  Able to provide informed conse

 Exclusion Criteria:

 -  Inability to participate in an informed consent process.

 -  Patients with a psychiatric disorder precluding response to the survey.

 -  Patients that are upstaged at the time of surgery and will require adjuvant therapy.