The Relationship Between NK Cell and Graves' Disease
The Relationship Between NK Cell and Graves' Disease
Graves' disease (GD) is one of organ specific autoimmune diseases, the pathogenesis is not
 elucidated.Natural Killer (Natural Killer, NK) cells is a kind of important immune regulator,
 several abnormalities of NK cell function and number in GD patients have been described in
 the investigators' previous study. It is remain unclear whether the NK cell disfunction is a
 consequence of GD.Based on the investigators' previous study, the investigators plan to
 monitor NK cell function in participants in the whole course of disease, analyze the
 association with relevant factors, such as thyroid function, immune state or treatment,to
 find out influences of thyroid hormones and thyroid receptor antibody affecting the function
 of NK cell. The investigators will reveal whether the disfunction of NK cell secondary to GD
 abnormal thyroid function and/or immune disorders, and realize the mechanics.
Inclusion Criteria:

 -  New GD patients without any treatment

 -  Aged of 18 to 75 years old

 Exclusion Criteria:

 -  Pregnant or lactating woman;

 -  Known autoimmune disease;

 -  Receiving psychotropic or hormonal drugs;

 -  Taking drugs that affect the body's immune function;

 -  Obviously poor compliance.