ARISE: After 8 Hours Reperfusion in Ischemic Stroke Embolization
ARISE: After 8 Hours Reperfusion in Ischemic Stroke Embolization
A prospective pilot study to evaluate the recanalization and safety of mechanical
 thrombectomy through a cerebral angiogram in patients with stroke symptoms last seen normal
 between 8 - 24 hours.
Ischemic stroke patients who are 8-24 hrs from symptom onset without prior mechanical or IV
 thrombolytic treatment and are screen with CT or MR perfusion imaging showing penumbra and
 infarction not > 1/3rd the territory.
Inclusion Criteria:

 -  Over 18 years last seen normal between 8 - 24 hours, without prior history of
 intravenous plasminogen activator (IV t-PA ) or

 -  mechanical thrombectomy Vessels - intracranial vertebral artery, basilar artery,
 intracranial ICA, ICA terminus bifurcation, MCA M1/M2, or

 -  ACA NIHSS ≥ 7 MRI DWI/PWI or

 -  CTA/P, which demonstrates an area of mismatch ≥ 2/3 rd

 -  Signed informed consent

 Exclusion Criteria:

 -  creat >= 2

 -  NIHSS < 7

 -  Baseline mRS >= 2

 -  infarct > 1/3rd MCA territory

 -  competing trials

 -  prior IV or IA treatment