Microbiota in Acute Pancreatitis: Prospective Multicenter Study
Microbiota in Acute Pancreatitis: Prospective Multicenter Study
The objective of the study is to classify and carry out a quantitative analysis of the
 different bacterial species present in the intestinal microbiota of patients with acute
 pancreatitis and determine if there are significant differences regarding healthy controls.
 At the same time, the investigators pretend to determine if there are differences according
 to the etiology and severity of the disease and if the disregulation is temporary or is
 maintained after one month of discharge.

 To carry out this purpose, the investigators have designed a prospective and multicentre
 observational study where samples of feces and saliva of patients admitted for acute
 pancreatitis of different etiologies and severity will be analyzed.
The study of the human microbiota is gaining importance given its relationship with the
 homeostasis of the organism as well as with certain pathologies. Specifically in the case of
 acute and chronic pancreatitis, recent studies suggest the disregulation of the intestinal
 flora as a possible determinant in the development and evolution of the disease. If this
 hypothesis is confirmed, hygienic-dietetic measures, as well as the administration of
 antibiotics, probiotics or fecal transplantation, may have therapeutic implications.

 The objective of the study is to classify and carry out a quantitative analysis of the
 different bacterial species present in the intestinal microbiota of patients with acute
 pancreatitis and determine if there are significant differences regarding healthy controls.
 At the same time, the investigators also intend to determine if there are differences
 according to the etiology and severity of the disease and if the disregulation is temporary
 or is maintained after one month of discharge.

 To carry out this purpose, it has been designed a prospective and multicentre observational
 study where samples of feces and saliva of patients admitted for acute pancreatitis of
 different etiologies and severity will be analyzed .
Inclusion Criteria:

 -  Case patients: adult patients diagnosed of acute pancreatitis according to Atlanta
 2012 criteria

 -  Healthy controls: healthy people with a proximity relationship with case patients and
 similar age (+/- 5 years. Doesn't have to be a parental relationship.

 Exclusion Criteria:

 -