Prospective Cohort Study With Central Nervous System Evaluation in Diffuse Large B-cell Lymphoma
Prospective Cohort Study With Central Nervous System Evaluation in Diffuse Large B-cell Lymphoma
This study is to evaluate the incidence of central nervous system (CNS) relapse or metastasis
 in patients with diffuse large B-cell lymphoma.
We dichotomize patients according to the risk of CNS involvement. Then, we perform CNS
 evaluation in patients at risk of CNS involvement. We prospectively monitor whether CNS
 relapse or metastasis occurs in patients with diffuse large B-cell lymphoma
Inclusion Criteria:

 1. Newly diagnosed patients with diffuse large B cell lymphoma

 2. > 20 years

 3. life expectancy more than 6 months

 4. Written informed consent

 Exclusion Criteria:

 1. Refusal to informed consent

 2. Lymphomas other than diffuse large B cell lymphoma

 3. Primary CNS lymphoma