Cryotherapy to Improve Outcomes in Lower Third Molar Surgery
Cryotherapy to Improve Outcomes in Lower Third Molar Surgery
This study is looking to see whether cooling the face using a special cooling device
 (Hilotherm®) before and during the removal of wisdom teeth will reduce the pain and
 discomfort patients feel after the procedure. The surgical removal of lower third molars
 (wisdom teeth) is arguably the most commonly performed surgical procedure worldwide. If this
 study shows that application of cold before and throughout the procedure is a simple way to
 reduce post-operative symptoms, it could benefit thousands of patients every year.
Inclusion Criteria:

 1. Patients 18+ years requiring surgical removal of a single (unilateral) mandibular
 wisdom tooth

 2. Tooth requiring full mucoperiosteal flap and bone removal for removal of tooth

 3. Written informed consent

 Exclusion Criteria:

 1. Patients refusing to give written informed consent

 2. Clinically significant or unstable physical or mental disability rendering the
 participants incapable of complying with the study protocol as judged by the
 investigator

 3. Pregnant women

 4. Patients taking long-term anti-microbial or anti-inflammatory drugs

 5. Patients requiring pre-operative antibiotics for surgery

 6. Patients requiring concomitant extractions or contralateral lower 3rd molar removal