Clinical Pilot Study of New Prosthesis for Trans-femoral Amputated Patients
Clinical Pilot Study of New Prosthesis for Trans-femoral Amputated Patients
Patients with a trans-femoral amputation who experienced problems, complications pain due to
 the ischial weight bearing and discomfort with conventional socket prosthesis will be
 proposed to implant a new developed prosthesis.
The patients will undergo a surgical operation to implant a femoral prosthesis according to
 the hospital's protocol. The surgical intervention will be performed under general or spinal
 anesthesia with a tourniquet at the root of the lower limb. Under sterile conditions, the
 incision of the stump will be done at the level of the previous surgical scar. Preserving the
 soft tissue, the distal femoral bone is reached. Then, the medullary canal is opened and
 prepared with reamers of increasing diameter. A femoral cemented stem of appropriate
 dimensions correlated to the size of the canal and 105 mm of height is implanted. To the
 above-mentioned stem, the Medacta prosthesis will be fixed with a blocking screw. The
 prosthesis is then covered with the soft tissue and layered suturing of the stump is
 performed.
Inclusion Criteria:

 -  Age >18 and <75 years

 -  Patients with Trans-femoral Amputations since at least 2 years and suffering from pain
 and discomfort with the current standard socket prosthesis, i.e., with a baseline VAS
 score for pain between 3 and 10 or a health-related quality of life (Eq-5D) score < 60
 or an SF-36 result below the 50th percentile

 -  Amputation due to:

 1. Trauma

 2. Oncologic disease

 -  Written informed consent

 Exclusion Criteria:

 -  Trans-femoral amputation due to infection

 -  Patients affected by

 1. metabolic disease

 2. neurologic degenerative disease

 3. vascular disease proximal to the amputation

 4. body weight >100 kg

 5. Hip arthritis of the amputated limb