Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
In the present study, midazolam and palonosetron in combination were more effective than
 palonosetron alone in lowering the incidence and severity of postoperative nausea and
 vomiting in the initial 2 h after laparoscopic cholecystectomy. Postoperative clinical
 complications were not different in both groups.
Inclusion Criteria:

 -  The patients (aged 20 to 65 years) scheduled for laparoscopic cholecystectomy with
 American Society of Anesthesiologists (ASA) physical status classification of 1 or 2

 Exclusion Criteria:

 -  The patients with a history of allergy to any other drugs used in this study,
 gastrointestinal disorder, previous PONV, pregnant woman, breastfeeding woman, use of
 antiemetics within 24 hours or body mass index > 30 kg/m2