Study of Lornoxicam or Ketorolac or Placebo for Post-Operative Pain After Bunionectomy
Study of Lornoxicam or Ketorolac or Placebo for Post-Operative Pain After Bunionectomy
To determine whether a single dose of intravenous lornoxicam is superior to intravenous
 placebo for management of post-operative pain in patients who have surgical removal of a
 bunion on the lower extremity. One-fourth of patients in this study will receive a single
 dose of intravenous ketorolac for management of pain and one-fourth of patients in this study
 will receive a single dose of an intravenous placebo.
Inclusion Criteria:

 -  Subjects who are scheduled for a primary unilateral first metatarsal bunionectomy
 under local anesthetic.

 -  Subjects have no contraindications to this surgery and have no allergies to the study
 medications or similar medications.

 -  Subjects are in generally good health with no uncontrolled chronic illnesses or
 diseases.

 Exclusion Criteria:

 -  Subjects who are pregnant.

 -  Subjects who have significant obesity.

 -  Subjects with medically significant heart, liver, kidney, lung or endocrine disease.

 -  Subjects with active viral disease, i.e. hepatitis, HIV.