Delayed Cord Clamping in Rhesus Disease of the Newborn
Delayed Cord Clamping in Rhesus Disease of the Newborn
The objective of this clinical trial is to investigate the effects of delayed cord clamping
 on hyperbilirubinemia, the need for phototherapy, neonatal intensive care (NICU) admission
The study will include term or preterm infants born to Rh negative mother.

 The enrolled infants will be randomized into two groups:

 Group (1) will include infants with delayed cord clamping performed at 60 sec after birth
 Group (2) will include infants with early cord clamping within 15 seconds.

 History and examination The data on the gender, gestational age, birth weight, length, head
 circumference, 5- minute Apgar scores, presence of jaundice requiring phototherapy or
 exchange transfusion, need for admission in neonatal intensive care unit, the presence of
 respiratory distress (RR > 60 breath per minute) ,and length of hospitalization will be
 recorded.

 The enrolled infants will be followed either with their mothers in the nursery or in NICU.
 Regarding the mothers; maternal age, maternal weight, any diseases, medication, and mode of
 delivery, and postpartum hemorrhage requiring blood transfusion will be recorded.
Inclusion Criteria:

 - term or preterm infants born to Rh negative mother

 Exclusion Criteria:

 -  Infants with Rh negative factor

 -  major congenital malformation

 -  fetal hydrops

 -  short umbilical cord less than 25cm

 -  nuchal cord

 -  multiple gestation

 -  unstable maternal hemodynamic condition

 -  placenta abruption

 -  placenta previa

 -  uterine rupture

 -  denied to participate

 -  depressed neonates who will require immediate resuscitation