A Prospective Study of Treating Duodenal Papillary Sphincter in Different Ways During ERCP
A Prospective Study of Treating Duodenal Papillary Sphincter in Different Ways During ERCP
Endoscopic retrograde cholangiopancreatography (ERCP) is commonly performed to remove bile
 duct stones.Endoscopic sphincterotomy (EST), endoscopic papillary balloon dilation (EPBD),
 and endoscopic sphincterotomy plus balloon dilation (sEST+EPBD) are 3 methods used to enlarge
 the papillary orifice, but their efficacy and safety remains controversial. This study aimed
 to compare these methods for treating common bile duct (CBD) stones.
Investigators first divided the patients with different sizes of common bile duct stones into
 two groups. The bile duct stone diameter of group A is less than 1.0cm while group B is more
 than 1.0cm and less than 1.5cm. Each group compared Endoscopic sphincterotomy (EST),
 endoscopic papillary balloon dilation (EPBD), and endoscopic sphincterotomy plus balloon
 dilation (sEST+EPBD) in ERCP. Through the postoperative comparison of relevant inspection
 test indicators, the recovery of patients, whether the occurrence of complications, including
 infection,bleeding,pancreatitis,perforation , and 1 year stone recurrence rate,Investigators
 assess the advantages and disadvantages in three different strategies in different sizes of
 common bile duct stones , and finally get a relatively objective evaluation to guide our
 daily ERCP work on the choice of duodenal papillary sphincter treatment strategy.
Inclusion Criteria:

 -  Age 20-80 years old

 -  CT or MRCP diagnose the patients with Common bile duct stones

 -  The diameter of the stone is less than or equal to 1.5cm

 -  Patients with the indications for ERCP

 -  Patients and their families agree to participate in the trial

 Exclusion Criteria:

 -  Stones are too large (> 1.5cm)

 -  A history of gastrointestinal surgery

 -  ERCP and EST or EPBD surgery history

 -  Patients generally poor, total bilirubin> 200umol / L or PT time extension> 3s

 -  Patients with mental illness or other serious heart and lung disease