The Role of Microparticles as a Biomarker
The Role of Microparticles as a Biomarker
The investigators propose to characterize MPs in aHUS and TTP both at the onset and
 throughout treatment. The investigators believe that the number, size, and cell origin of MPs
 will differ between these two diseases. The hypothesis is that endothelial derived MPs will
 be higher in number and comprise a larger portion of the MP population in aHUS and that
 platelet MPs will comprise a larger number and greater proportion of MPs in TTP. The
 investigators believe that MP identity and number can be used to reliably differentiate
 between aHUS and TTP at disease onset.
Inclusion Criteria:

 -  Patients with MAHA, TTP, and/or aHUS

 Exclusion Criteria:

 -  Prisoners