Congenital Hypothyroidism in Children With Eutopic Gland or Thyroid Hemiagenesis: Predictive Factors for Transient vs Permanent Hypothyroidism.
Congenital Hypothyroidism in Children With Eutopic Gland or Thyroid Hemiagenesis: Predictive Factors for Transient vs Permanent Hypothyroidism.
In France, the incidence of congenital hypothyroidism has increased significantly since the
 newborn screening program was introduced in 1978. The largest increase is seen in children
 with eutopic thyroid gland. More than one-third of children with eutopic gland have transient
 hypothyroidism. Clinical practice guidelines recommend to re-evaluate thyroid function in
 children with eutopic gland around the age of 3 years to determine whether hypothyroidism is
 transient or permanent. Up until today it is still difficult to determine early on whether
 hypothyroidism is transient or permanent in children with eutopic gland. Our aim is to
 identify one or more predictive factors for transient congenital hypothyroidism in children
 with eutopic gland or thyroid hemiagenesis.
Inclusion Criteria:

 -  Children with congenital hypothyroidism

 -  Eutopic thyroid gland or thyroid hemiagenesis

 -  Born between 1996 and 2017

 -  Treated at the Nancy Regional and University Hospital

 -  Follow-up of at least 3,5 years.

 Exclusion Criteria:

 -  Polymalformative syndrome

 -  Thyroid dysgenesis except for thyroid hemiagenesis