Sufentanil on Anesthesia Introduction and Recovery Quality in Pediatric Adenotonsillectomy
Sufentanil on Anesthesia Introduction and Recovery Quality in Pediatric Adenotonsillectomy
To study the effect of different doses of sufentanil on anesthesia induction and analgesia
 after tonsillectomy in children. According to the different doses of sufentanil used in
 anesthesia induction, the children were divided into 3groups. The vital signs during
 anesthesia, the recovery period of anesthesia and the complications after anesthesia were
 compared among the groups. The anesthetic effects and safety of sufentanil at different doses
 were discussed, which provided theoretical basis for clinical selection of the best drug
 dosage.
Fifteen minutes before operation, midazolam 0.1 mg/kg was slowly intravenously injected. Five
 minutes later, the child entered the operating room. Pi, Narcotrend, blood pressure, ECG,
 SpO2 and body temperature were monitored. Penehyclidine hydrochloride 0.01 mg/kg,
 dexamethasone 0.1 mg/kg, propofol 3 mg/kg, sufentanil (0.3μg/kg, 0.4 μg/kg, 0.5 μg/kg) were
 given during anesthesia induction. cis-atracurium 0.15 mg/kg, using the required type of tube
 for tracheal intubation. Sevoflurane 1.0 MAC + remifentanil 0.15 ug/kg/min 50% oxygen was
 given during anesthesia maintenance. Effective analgesia was achieved by adjusting the dosage
 of remifentanil during operation.

 The changes of vital signs including perfusion index, Narcotrend, Bp, HR, oxygen saturation
 were observed before anesthesia induction, immediately after tracheal intubation, during
 tonsillectomy and adenoidectomy during operation, after extubation and in the recovery room.
 Then record the recovery time, restlessness and pain score during recovery period,
 postoperative pain, nausea and vomiting and other complications.
Inclusion Criteria:

 -  Age 1-12 years,

 -  ASA I-II grade;

 -  selective adenotonsillectomy

 -  BMI 18.5～23.9,

 -  Sign informed consent

 Exclusion Criteria:

 -  Emergency surgery;

 -  Abnormal liver and kidney function

 -  severe dehydration and malnutrition or Hb < 10g/dl;

 -  BMI <18.5 or <23.9;

 -  Children with neurological disorders