Treatment of Multiple Attacks of Acute Migraine (0462-025)
Treatment of Multiple Attacks of Acute Migraine (0462-025)
A study to evaluate rizatriptan for the treatment of multiple attacks of acute migraine
 compared to placebo.
Inclusion Criteria:

 -  Patient had at least a 6-month history of migraine, with or without aura

 -  Patient was male, or if female must have been postmenopausal, surgically sterilized,
 or taking adequate contraceptive precautions.

 -  Patient was judged to be in good health, apart from migraine

 Exclusion Criteria:

 -  Patient was pregnant or a nursing mother.

 -  Patient had abused drugs or alcohol within 12 months prior to entering the study

 -  Patient had a history of cardiovascular disease

 -  Patient had clinically significant ECG abnormality

 -  Patient had a resting systolic blood pressure of greater than 145 mm Hg or diastolic
 of less than 95 mm Hg at screening

 -  Patient received treatment with an investigational device or compound within 30 days
 of the study start

 -  Patient typically suffered from less then 1 or more than 8 attacks of migraine per
 month

 -  Patient had difficulty in distinguishing his/her migraine attacks from tension or
 interval headaches

 -  Patient had prior exposure to rizatriptan