Population-based Brest Stroke Registry
Population-based Brest Stroke Registry
The registry is the main objective exhaustive list of cases validated stroke brain on a
 geographical area defined to calculate an incidence.
The main objective of Brest Stroke Registry is to regroup all confirmed cases of stroke over
 a defined geographical zone in order to calculate an incidence.

 There are three prospective medium-term goals:

 - In respect with public health epidemiology:

 1. To obtain incidence data and evaluate the regional and international divergences

 2. To obtain the mortality data in short and long term. Since the onset of the registry, it
 has been implemented a study on the mortality of stroke patients of Brest Registry. This
 study has been realized independently for both types of stroke, i.e. ischemic and
 hemorrhagic, with different caused mortality. This mortality was studied at medium-term
 (≤ 28 days) as well as at long-term (> 28 days). There will be a collaboration project
 between Public Health Surveillance (InVS), Brest University Hospital and Rennes network
 on all causes of death.

 3. Pharmaco-epidemiology

 In clinical terms, the registry offers an opportunity to do an inventory of all current
 practices (diagnosis, therapies and the subsidiaries) and propose in this manner the best
 management of stroke. This strategy is in line with the pilot programs deployed by the French
 High Health Authority (HAS) for improvement of quality and safety of the health care. The
 bleeding risk associated with anticoagulants and anti-platelet agents in people of Brest as
 well as that of Dijon and Lille (in collaboration with their respective registry) will be
 analyzed.

 This study has gained a particular characteristic since 2012 with emerging new oral
 anticoagulants (OAC) which have shown less associated bleeding risks compared with vitamin K
 antagonists (randomized controlled trials).

 •In terms of clinical research :

 1. Study the impacted consequences of stroke by socio-economic characteristics of the
 territories in the Pays de Brest

 2. Identify short and long term clinical predictors of mortality in patients who have had a
 hemorrhagic stroke.

 3. To identify clinical predictors of mortality in the short and long-term patients with
 ischemic stroke.

 4. To identify genetic predictors of mortality and long-term recurrence of patients with
 ischemic stroke

 5. Identify stroke identification algorithm from existing databases
Inclusion Criteria:

 -  Diagnostic validated for one of the following pathologies:

 -  Ischemic stroke,

 -  Non-traumatic intracranial hematoma

 -  Cerebral venous thrombosis Diagnostic after December 31, 2007 Age > 15 years on the
 date of the diagnostic Patient domiciled at the time of the diagnostic in one of the
 79 communes defined beforehand

 Exclusion Criteria:

 -  Age ≤ 15 years

 -  Validated diagnosis (see below, § 4.2.2) of aneurysmal subarachnoid hemorrhage
 cerebrovascular

 -  Diagnosis made before 1 January 2008

 -  Unconfirmed diagnosis

 -  Patient domiciled outside the previously defined area of residence