Open Appendectomy Versus Laparoscopic Appendectomy
Open Appendectomy Versus Laparoscopic Appendectomy
1. Laparoscopic appendectomy may not be a superior procedure when compared with open
 appendectomy; 2. Various modifications in laparoscopic appendectomy procedure may reduce the
 technical diffuculty and overall costs.
The study will be a prospective randomized clinical trial. Totally 150 patients who are
 diagnosed to have acute appendicitis will be randomly divided into 3 equal groups (n=50 for
 each group). First group will have traditional open appendectomy procedure; second group will
 have laparoscopic appendectomy procedure in which appendiceal stump is secured by metal
 endoclips; and third group will have laparoscopic appendectomy procedure in which appendiceal
 stump is secured by intracorporeal suture ligation. The preoperative parameters that will be
 obtained for all patients are: detailed information for communication, patient history, age,
 gender, the presence of spesific symptoms (nausea, vomiting, loss of appetite, right lower
 quadrant pain), the presence of clinical signs, laboratory findings, and radiological
 findings. The peroperative parameters that will be recorded are: operative time, the type and
 the length of incisions, the number of trocars, operative findings, details of laparoscopic
 technique, generic name of prophylactic antibiotic, and the presence of additional findings.
 All of the patients will undergo a clinical evaluation by attending surgeon on the 5th, the
 15th, and the 30th postoperative day. The postoperative clinical evaluation will include the
 examination of the patient for surgical site infection and other wound complications, and the
 performance of a spesific quality-of-life index questionnaire. In the end of the study, all
 parameters and quality-of-life scores will undergo statistical analysis.
Inclusion Criteria:

 -  The patients with a preoperative diagnosis of acute appendicitis

 Exclusion Criteria:

 -  The patients who are not volunteered to join the study

 -  The patients who are diagnosed to have peroperative or histopathological pathology
 other than acute appendicitis

 -  The patients who have additional pathologies accompanying acute appendicitis