Impact of Aerobic Training and Combined in Inflammatory Markers in Patients With Adolescent Idiopathic Scoliosis
Impact of Aerobic Training and Combined in Inflammatory Markers in Patients With Adolescent Idiopathic Scoliosis
Inflammatory markers have been analyzed in several diseases of unknown etiology, in the
 expectation of increasing therapeutic perspectives. This possibility arises from the
 different levels of tissue injury with low-grade chronic inflammation that have been observed
 in studies in which the markers were not evaluated traditionally, and today have influenced
 clinical management.

 The investigators aimed, therefore, to evaluate the inflammatory markers in patients with AIS
 before and after aerobic and combined exercise training.
Inflammatory markers have not been evaluated in adolescent idiopathic scoliosis (AIS), but
 this deformity potentially involves various musculoskeletal structures permanently, which
 justifies the analysis. A low-grade chronic inflammation may be related to the lower capacity
 in exercise performance observed in this population, which must be stimulated to perform
 standardized physical activity.
Inclusion Criteria:

 -  thoracic curvature ≥ 45 degrees

 -  indication for surgical treatment of spinal deformity

 -  absence of pulmonary, cardiac, articular or neurological disorder, atopic dermatitis
 and previous or current allergy

 -  agree part in the research with a assent statement and the person responsible with the
 consent form and informed

 Exclusion Criteria:

 -  acknowledged chronic liver or kidney inflammatory disease

 -  use of corticosteroids, acetylsalicylic acid or other nonhormonal anti-inflammatory
 clinical or laboratorial evidence of infection

 -  severe obesity