Plasma Rich in Growth Factors (PRGF-Endoret) in the Regeneration of Post-Extraction Sockets
Plasma Rich in Growth Factors (PRGF-Endoret) in the Regeneration of Post-Extraction Sockets
Immediately following tooth removal, a healing process begins that affects the eventual
 alveolar bone volume and architecture of the alveolar ridge. Satisfactory and timely healing
 are essential to obtain ideal functional reconstruction. Traumatic removal of a tooth, or a
 poor healing response, may lead to excessive bone loss delaying tooth replacement, requiring
 expensive and time-consuming reconstructive surgeries, or even the inability to be corrected.
 The Plasma Rich in Growth Factors (PRGF-Endoret) has shown its therapeutic potential effect
 to minimize the consequences of this aggression, promoting the regeneration of both hard and
 soft involved tissues.
Inclusion Criteria:

 -  subjects of both genders and ≥ 18 years old

 -  Indication of a simple one molar extraction in the mandible.

 -  Possibility of observation during the follow-up period.

 Exclusion Criteria:

 -  Unerupted third molars or with horizontal inclination.

 -  Severe swelling prior to surgery in the areas designated for extraction.

 -  Suffering an alteration or a serious hematologic disease.

 -  Be currently undergoing or have received radiotherapy, chemotherapy or
 immunosuppressive therapy, corticosteroids and/or anticoagulants 30 days prior to
 inclusion

 -  In regular treatment with NSAIDs or other anti-inflammatory drugs.

 -  History of chronic hepatitis or cirrhosis.

 -  Diabetes mellitus with poor metabolic control (glycosylated hemoglobin >9%)

 -  Patients undergoing dialysis.

 -  Presence of malignant tumors, hemangiomas or angiomas in the extraction area.

 -  History of ischemic heart disease in the last year.

 -  Pregnancy or planned pregnancy during the study follow-up period.

 -  Metabolic Bone Disease.

 -  Patients taking bisphosphonates both orally and intravenously.

 -  In general, any inability to participate in the study.