Cerebral Infarction and White Substance in Angiopathy Cerebral Amyloid
Cerebral Infarction and White Substance in Angiopathy Cerebral Amyloid
The cerebral amyloïd angiopathy ( AAC) is a disease characterized by deposits of beta-amyloid
 peptids in the walls of the arteries of young and average calibre of the brain and the
 leptomeninx. The incidence of the AAC increases strongly with the age and represents a major
 cause of spontaneous brain haemorrhage to people over 60. The main demonstration is the lobar
 brain haemorrhage, the other ones are bleedings under arachnoid cortical and microbleedings
 leading to cognitive decline.

 Anatomical studies reported the presence of cortical infarcts in patients having amyloïd
 deposits suggesting an association between asymptomatic cortical cerebral infarcts and AAC.

 However prevalence and meaning of these infarcts in patients having an AAC remain badly known
 because of studies on low number of patients and the rarity of radiological analyses of these
 infarcts .A better knowledge of these asymptomatic cortical infarcts would allow to dread
 better cognitive disorders(confusions) presented by these patients, and to develop preventive
 strategies.

 Besides, the risk factors of severity of the AAC are little studied.
Inclusion Criteria:

 -  age>55

 -  hospitalized in CAEN hospital and Paris St Joseph Hospital between 1st january 2011
 and 31 december 2015 for cerebral haemorrhage with MRI images diagnosing cerebral
 amyloid angiopathy.

 Exclusion Criteria:

 -  Insufficient MRI images quality without FLAI sequence, T2 GRE

 -  disease with same radiologic and clinical signs that cerebral amyloid angiopathy.