Identification of Correlates of Protection Against Shigella and Enterotoxigenic Escherichia Coli Infections
Identification of Correlates of Protection Against Shigella and Enterotoxigenic Escherichia Coli Infections
The aim of this study is to accelerate the development of vaccine candidates against
 diarrheal diseases caused by Shigella and Enterotoxigenic Escherichia coli (ETEC). We plan to
 identify cases of laboratory-proven shigellosis and ETEC-associated diarrhea, to study
 humoral and cellular immune parameters following natural infections with Shigella and ETEC,
 and to compare the level of pre-existing local, humoral and cellular immune parameters in
 cases of shigellosis and ETEC-associated diarrhea and in matched controls.
Inclusion Criteria:

 -  Lab-confirmed Shigella or ETEC

 -  Individuals or patients without diarrheal disease

 Exclusion Criteria:

 -  n/a