Reobtain Coronary Ostia Cannulation Beyond Transcatheter Aortic Valve Stent (RE-ACCESS)
Reobtain Coronary Ostia Cannulation Beyond Transcatheter Aortic Valve Stent (RE-ACCESS)
With the upcoming expansion of transcatheter aortic valve replacement (TAVR) indications to
 younger patients, the feasibility of coronary ostia cannulation beyond different
 bioprosthesis stent is currently a matter of debate. Purpose of this study is: 1) to assess
 the feasibility to re-engage coronary ostia after TAVR; 2) to discover potential native
 anatomical or prosthesis-related features that may preclude proper coronary cannulation after
 TAVR.
Single-center, prospective, pilot study. Aim of this study is to assess the feasibility of
 coronary ostia re-engagement beyond transcatheter aortic valve (TAV) stent through a
 transfemoral access in 300 consecutive patients undergoing transfemoral TAVR with
 pre-procedural computed tomography assessment available.

 The possibility to selectively cannulate each coronary, the amount of time and contrast will
 be evaluated in each patient before and after implantation of either balloon-(SAPIEN 3) or
 self-expanding (Evolut R/PRO, Acurate Neo or Portico) TAVs, thus generating an internal
 comparator.
Inclusion Criteria:

 -  Consecutive patients with severe aortic stenosis undergoing TAVR with all commercially
 available devices

 -  Availability of preprocedural aortic root evaluation by computed tomography
 angiography scans

 Exclusion Criteria:

 -  TAVR in degenerated bioprostheses

 -  Known ostial chronic total occlusion

 -  Transcatheter valve not deployed in its anatomical position

 -  Patients with hemodynamic instability during the procedure