The Influence of Benign Prostatic Hyperplasia on Bladder Function
The Influence of Benign Prostatic Hyperplasia on Bladder Function
Lower urinary tract symptoms(LUTS) are the main symptoms of benign prostatic
 hyperplasia(BPH), a benign but progressive disease which can advance to be with overactive
 bladder(OAB) symptoms. Moreover, LUTS and OAB symptoms can badly influence patients'
 especially the elderly's quality of life. Therefore, it appears to be urge to carry out
 researches on the functional impairment of bladder along with the advance of BPH. Besides,
 the management aimed at improving the LUTS and OAB symptoms come to be the key one among the
 management of BPH. For a long period, medication and surgery sustain to be the two most
 common therapies for BPH patients. Both patients and urologists prefer pharmacotherapeutics
 to surgery，which contributes to the rising number of BPH patients companied with OAB symptoms
 and storing symptoms complaint post-surgery. In fact, investigators usually find bladder
 impairment macroscopically in the BPH surgery: mild may be the trabeculation, worse can be
 the cabin, and severe may be the diverticula. Furthermore, it's not uncommon that patients
 with a long BPH history continually suffer from dysuria after surgery due to the detrusor
 muscle weakness. Consequently, investigators need to catch a moment when investigators should
 operate on such a patient in order to harvest a satisfying outcome. And perhaps the moment
 should be ahead of the existing guideline suggests. Thus, for understanding the influence of
 BPH on bladder function, investigators plan to conduct a prospective, case-control study
 recruiting in-patients with different degree of obstruction. Our team wish that such a
 clinical trail could provide valuable evidence for us to find out relatively better operating
 timing and serial indications. For the purpose of improving the quality of life and prolong
 life-span, investigators design the study above to maximum the operating outcome and minimize
 the bladder dysfunction.
Inclusion Criteria:

 1. Sign the informed consent.

 2. The BPH in-patients who take 'dysuria' as the main self-reported symptom and meet the
 following conditions, 1) Maximal urinary flow rate less than 20 ml per second, 2)
 Volume of prostate more than 20ml measured by transrectal ultrasound 3) PSA ranges
 from 0 to 10ng/ml 4) IPSS>1

 Exclusion Criteria:

 1. The lower urinary tract obstruction caused not by BPH

 2. Had a history of prostate cancer, surgery for benign prostatic hyperplasia or
 neurogenic bladder.

 3. using medications known to affect urination or had a severe concomitant disease