Characterization of the Profile of Dysarthria in Huntington's Disease, Using the Clinical Evaluation Battery of Dysarthria
Characterization of the Profile of Dysarthria in Huntington's Disease, Using the Clinical Evaluation Battery of Dysarthria
Huntington's disease is a hereditary disease of rare autosomal dominant transmission, both
 neurodegenerative and neuro-psychiatric. Clinically, there are motor symptoms (chorea),
 cognitive disorders (dementia) and psychiatric disorders.

 Among motor disorders, dysarthria is a commonly found symptom. This is classically referred
 to as hyperkinetic dysarthria according to the criteria of Darley's classification. However,
 this old classification (1969) is only based on perceptual analysis and lack of specificity.

 Moreover, in the course of the disease, chorea (control of the striatal attack D2) decreases
 to give place to a parkinsonian syndrome (control of the striatal attack D1) and the
 dysarthria also evolves towards a hypokinetic form . It also seems likely that cerebellar
 involvement (responsible for ataxia) contributes to dysarthria.

 No studies have been published to date to characterize dysarthria in Huntington's disease in
 a quantified, objective and specific manner. However, Canan Ozsancak describes choreic
 dysarthria as heterogeneous according to the patients and variable according to the
 productions. A perceptual study reports an imprecision of the consonants, a lengthening of
 the pauses, a variable flow, an absence of modulation of the pitch and a hoarse voice.

 Finally, few patients are cared for in speech therapy and there is no specific rehabilitation
 strategy: this would require - and justify a more precise study of the dysarthria of these
 patients.

 The Clinical Evaluation of Dysarthria developed by Pascal Auzou and Véronique
 Rolland-Monnoury is a recent and partially standardized tool, combining qualitative and
 quantitative evaluation, which seems adapted to try to better characterize the dysarthria in
 Huntington's disease.
Inclusion Criteria:

 -  Diagnosed Patients HD

 -  Major Patients

 -  French-speaking patients

 -  MMS score greater than 20

 -  Patients with informed consent signed

 -  Patients covered by a social insurance system

 Exclusion Criteria:

 -  Patients with intercurrent pathologies or other psychiatric disorders that may
 interfere with battery replacement (at the discretion of the investigator)

 -  Illiteracy

 -  Persons placed under safeguard of justice (adults under guardianship or guardianship)
 or deprived of their liberty