Emergence of Gram-negative Resistance in Blood Culture Isolates of Solid-organ Transplant Recipients
Emergence of Gram-negative Resistance in Blood Culture Isolates of Solid-organ Transplant Recipients
The information collected will provide insight in to the epidemiology of antibiotic
 resistance in a transplant compared to a non-transplant population. Data is needed regarding
 the date of admission, date of bloodstream infection and location of ward/ICU so trends in
 the emergence of resistance and antibiotic usage can be detected.
We need to collect details on the demographics (age, sex etc), underlying conditions,
 transplant types and immunosuppression, in-hospital antibiotic management and clinical
 outcomes so that the effect of antibiotic resistance on patient outcome can be measured. We
 also need to collect microbiology and pathology data to determine the antibiotic
 susceptibility profile of the involved organisms. The following variables will be followed:
 time and location of positive cultures, underlying diseases and severity of illness,
 prophylactic antimicrobials, physical exam findings, laboratory and radiographical data,
 empiric antimicrobial usage, microbiological data and resistance patterns, choice of
 antibiotic once organism identified, suspected source of infection, microbiological and
 clinical outcomes, laboratory results, demographic information, medications, gender, weight,
 ethnicity, and past medical history
Inclusion Criteria:

 -  All patients with a positive blood culture isolate growing a gram-negative organism
 will be included from 1996 - 2005