Vitamin Deficiency in Immigrants, a Treatment Study
Vitamin Deficiency in Immigrants, a Treatment Study
The purpose of this study is to determine the efficacy of different doses of vitamin D in
 persons, immigrated to Sweden from Middle East or Africa, with decreased S vitamin D.
The participants in the study have taken part in a previous screening study. They are now
 asked to participate in this treatment study. At a screening visit blood samples for vitamin
 D3 and PTH are collected. Data regarding previous fractures, life style, exposure for sun,
 clothes, diet, smoking and physical activities are collected. The Vitamin D value predict the
 treatment dose.
Inclusion Criteria:

 -  Serum- vitamin D below 75 nmol/L

 -  Men and female

 -  25-65 years of age

 -  Born in Middle East or Africa, living in Umeå district

 Exclusion Criteria:

 -  Hypersensitive to Cholecalciferol, cocos oil, palm kernel or rubber

 -  Serum D3 equal to or above75 nmol/L

 -  Hypercalcemia

 -  Renal insufficiency

 -  History of Kidney Calculi

 -  Nephrocalcinosis

 -  History of sarcoidosis and other Granulomatous Diseases

 -  Known malignancy

 -  Ongoing treatment with phenytoin, barbiturates, rifampicin, isoniazid

 -  Ongoing treatment with cardiac glycosides

 -  Ongoing treatment with thiazides

 -  Ongoing treatment with Etalpha, Rocaltrol, ergocalciferol, Dygratal

 -  Ongoing treatment with drugs involving fat absorption; Orlistat Colestyramin

 -  Oral treatment with glucocorticoids

 -  Ongoing treatment with Aluminum Compounds drugs

 -  Ongoing treatment with Omega -3, vitamin D and/or calcium

 -  Immobilisation

 -  Other medial reason not to participate according to the investigator

 -  Pregnancy (women with S-D3 below 25 nmol/)

 -  Breastfeeding