Tolerance Study of the Dietary Supplement Valedia
Tolerance Study of the Dietary Supplement Valedia
The objectives of this clinical study are to determine the tolerance of dietary supplement
 Valedia (blend of plant extracts) through the evaluation of several parameters :

 -  Various blood biological parameters for tolerance (preprandial): blood glucose, insulin,
 fructosamine, total cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol,
 oxidized LDL, us-CRP, creatinine, ASAT, ALAT, gGT, phosphatase alcaline, bilirubine,
 urea.

 -  Urinary parameters: urea, creatinine.

 -  Hemodynamic parameters: heart rate and blood pressure.

 -  Cardiac function: ECG.

 -  Weight.
Main Inclusion Criteria:

 -  25 <= BMI < 30 kg.m2

 Main Exclusion Criteria:

 -  ASAT <= 1,55 microkat/L

 -  ALAT <= 1,70 microkat/L

 -  gGT <= 2,55 microkat/L

 -  55 <= Creatinine <= 104 micromol/L (+- 10%)

 -  Bilirubin < 17,1 micromol/L (+- 10%)

 -  1,7 <= Urea <= 8,3 mmol/L (+- 10%)

 -  us-CRP <= 5 mg/L (+- 10%)

 -  0,70 <= Fasting glycemia <= 1,25 g/L (+- 10%)

 -  HbA1c <= 6%

 -  Medications for diabetes and/or dyslipidemia