Safety of Trypan Blue on Endothelium of Diabetic Retinopathy Patients
Safety of Trypan Blue on Endothelium of Diabetic Retinopathy Patients
This study examines the use of Trypan Blue staining of the corneal endothelium in patients
 undergoing phacoemulsification. It is a single-center prospective, randomized individual
 cohort study. One eye in each patient with diabetic retinopathy will undergo
 phacoemulsification without Trypan Blue capsule staining (control eye) while the other eye
 will undergo phacoemulsification with Trypan Blue capsule staining (study eye). Both eyes
 will undergo intraocular lens implantation. Preoperative and four-week postoperative
 quantitative and qualitative morphometric endothelial cell analyses of the cornea will be
 performed using noncontact specular microscopy.
Inclusion Criteria:

 -  Patients with bilateral cataract and diabetic retinopathy

 Exclusion Criteria:

 -  History of ocular surgery Active

 -  ocular inflammation Corneal opacities

 -  Pseudoexfoliation syndrome

 -  Anterior chamber flare and (or) other signs of possibly altered blood - queous barrier

 -  Iris neovascularization (rubeosis)

 -  Uncontrolled glaucoma

 -  Congenital or traumatic cataracts

 -  History or present chronic use of topical or systemic steroids

 -  Poor papillary dilatation (<6 mm)

 -  Specular microscopy cell density < 2000 cell/mm2

 -  Patients who experienced complications fromphacoemulsification