Laparoscopic Versus Open Devascularization for Portal Hypertension, a Randomized Controlled Trial
Laparoscopic Versus Open Devascularization for Portal Hypertension, a Randomized Controlled Trial
Many patients with portal hypertension require surgical treatment each year,and Hassab's
 operation, or esophagogastric devascularization and splenectomy, is an elective procedure. In
 recent years,laparoscopic esophagogastric devascularization and splenectomy has been used to
 treat portal hypertension. However, the potential benefits remain to be demonstrated in the
 context of a randomized trial. In this study, 120 patients will randomize equally receiving
 laparoscopic or open esophagogastric devascularization and splenectomy. Inclusion criteria
 included: platelet count < 50×109/ml, esophageal and gastric varices revealed, agreeing the
 informed consent. PerioperativeOutcomes are: technical success, blood loose and infusion
 during the operation, recurrent varicose veins on gastroscopy examination, patterns of reflux
 on duplex ultrasound examination, complications, platelet and liver function variation,
 length of hospital stay. Follow-up will last 5 years, and gastroscopy and ultrasonic will
 perform at 3 months, 1 year, 3 years, and 5 years. Further more, this study was proved by the
 ethical committee of second hospital of Xi'an jiaotong university.
Inclusion Criteria:

 -  The cause of portal hypertension was cirrhosis

 -  Platelet count < 50×109/ml

 -  Esophageal and gastric varices revealed

 -  Agreeing the informed consent.

 Exclusion Criteria:

 -  Thrombosis present in portal vein preoperatively

 -  Accompany with liver cancer

 -  Operation procedure is laparoscopy converse to open

 -  Patients disagree with the study.