Efficacy and Safety of NT 201 in the Treatment of Lateral Periorbital Wrinkles
Efficacy and Safety of NT 201 in the Treatment of Lateral Periorbital Wrinkles
To investigate the efficacy and safety of incobotulinumtoxinA (Xeomin) in comparison to
 placebo in the treatment of moderate to severe lateral periorbital wrinkles at maximum smile
 and to compare two different application schemes of Xeomin. Each subject will be treated on
 the right and left eye area, using the same dose but different application schemes (i.e. 3 or
 4 injection sites).
Conducted in Europe
Main Inclusion Criteria:

 - Moderate (grade 2) to severe (grade 3) symmetrical lateral periorbital wrinkles assessed
 by the investigator according to the 4-point scale at maximum smile

 Main Exclusion Criteria:

 - Significant facial asymmetry