Comparative Analysis of Serum Lipid Profiles in Patients With and Without Gallstones
Comparative Analysis of Serum Lipid Profiles in Patients With and Without Gallstones
Gallbladder disease is one of the most common diseases of the gastrointestinal tract. Various
 studies have shown an association between gallstones and an alteration in the serum lipids.
 The objective of this study will be to compare serum lipid profile of gallstone patients with
 the controls.
This prospective cross-sectional study will be conducted in the Surgical Department of the
 Services Institute of Medical Sciences. A total of 50 patients will beincluded in the study
 after screening through the inclusion criteria. A control group of 50 inpatients with no
 personal or family history of gallstones will be also recruited for comparison. Results will
 be expressed as mean with standard deviation. Students t- test will be used to compare the
 data between the patients and the control groups (p<0.05 will be considered statistically
 significant). SPSS software, version 20 will be used for statistical analysis.
Inclusion Criteria:

 -  Male or female patients with the gall stone disease

 -  Age from 20 to 70 years

 -  Gallstones were diagnosed through the ultrasound

 Exclusion Criteria:

 -  Patients with acalculous gallbladder disease on ultrasound,

 -  Patients with terminal ileal resection,

 -  Patients with hemolytic diseases (hereditary spherocytosis, sickle cell anemia on
 history and CBC film),

 -  Patients with liver cirrhosis (on abdominal ultrasound) and

 -  Patients on antihyperlipidemic drugs