What is the Incidence of an Immune Disorder in Children With Invasive Pneumococcal Disease (IPD)?
What is the Incidence of an Immune Disorder in Children With Invasive Pneumococcal Disease (IPD)?
This is a multicentre prospective audit to determine the incidence of immunodeficiency in
 children with IPD.

 Aims and/or research question of the project

 1. To determine the incidence of primary immunodeficiency in children >2 years who present
 with IPD

 2. To determine the types of immunodeficiency associated with IPD in children
Inclusion Criteria:

 -  Children aged 0 to 18 years admitted to one of the six centres with IPD.

 Exclusion Criteria:

 -  Children who do not fulfil the age criteria for immunological evaluation at that
 particular site e.g. aged <2 years at Royal Children's Hospital.

 -  Children with a known underlying condition predisposing to IPD i.e. nephrotic
 syndrome.