Dosimetric Planning Study Comparing Intensity Modulated Radiotherapy (IMRT) and 4-field Radiotherapy for Definitive Treatment of Cancer of the Cervix
Dosimetric Planning Study Comparing Intensity Modulated Radiotherapy (IMRT) and 4-field Radiotherapy for Definitive Treatment of Cancer of the Cervix
A theoretical planning study to compare the normal tissue irradiation when using intensity
 modulated radiotherapy (IMRT) as opposed to standard radiotherapy for the definitive
 treatment of cervical cancer.
Radiotherapy in combination with chemotherapy is the standard treatment of locally advanced
 cervix cancer, however with traditional techniques large volumes of bowel and bladder are
 irradiated causing short-term and long-term genito-urinary and gastro-intestinal side
 effects. IMRT has the potential to conform precisely to the target and spare normal tissues
 and reduce side effects. However because there are large dose gradients there is the
 potential to miss the target due to organ motion. Recent studies have documented organ motion
 and will be used to define the target. Approximately 60 planning scans, previously used to
 treat patients with cervix cancer, will be used to replan using an IMRT technique and
 differences in doses to tumour and normal tissues compared.
Inclusion Criteria:

 -  last 60 patients treated definitively for cervical cancer at Sunnybrook Odette Cancer
 Centre

 Exclusion Criteria:

 -  no imaging and no anatomical description of disease