Identification of Gene Biomarkers in Aging Skin
Identification of Gene Biomarkers in Aging Skin
This study is a blinded, prospective, single-center, clinical study conducted in Japanese
 female subjects between the ages of 20-75 years. This design uses skin biopsy samples from
 environmentally exposed areas and unexposed (control) areas within the same subjects to
 assess the gene expression profile from three different age groups.
The primary objective of the skin aging study is to investigate changes in gene expression
 patterns that occur during the aging process.
Inclusion Criteria:

 -  Individuals who are willing to read and sign an informed consent form prior to
 participating in the study.

 -  Individuals who have a temperature of less than or equal to 100 degrees F at the time
 of biopsy collection.

 -  Individuals who had not applied any sunless tanning product on the arms within the
 past year.

 -  Individuals with no prior history of alcoholism (or who consume fewer than 2 to 3
 alcoholic beverages per day).

 -  Individuals who have not consumed any anti-aging nutritional supplements
 (multivitamins and multiminerals are acceptable) or aspirin, NSAIDS, or other pain
 medication in the last 48 hours before biopsy.

 Exclusion Criteria:

 -  Male gender

 -  Individuals who did not fit the 'inclusion criteria' above.