Effects of Yoga on Metabolic Syndrome
Effects of Yoga on Metabolic Syndrome
Metabolic syndrome (MetS) is a clustering of cardiovascular risk factors characterizing
 central obesity, insulin resistance, dyslipidemia and high blood pressure. The concept of
 MetS represents the pre-cardiovascular and pre-diabetic pathologic conditions, which has been
 a useful tool in prognosing the development of cardiovascular disease and diabetes mellitus.
 Importantly, interventions applied at the pre-pathologic stage with MetS would be of great
 clinical and health significance in achieving better preventive and therapeutic outcomes.
 Yoga, a mind-body exercise, has been suggested to have beneficial effects on dyslipidemia,
 hypertension and diabetes. A pilot study has demonstrated the trends in the improvement of
 metabolic parameters in middle-aged adults with MetS but the findings are inconclusive
 because of the small sample size and brief yoga follow-up period (i.e., 2-month). In addition
 to the needs of a better designed randomized controlled trial in studying the beneficial
 effect of yoga in controlling MetS in middle-aged individuals, the investigation on yoga and
 MetS in elderly population has been lacking. This is important as the potential use of yoga
 as lifestyle modification in elderly individuals with MetS will result in significant
 reduction of the prevalence of cardiovascular disease and diabetes. Thus, this study aims to
 examine the efficacy of yoga exercise in improving metabolic abnormalities in middle-aged and
 older adults with MetS. In addition to elderly, middle-aged adults are included in the
 present investigation because of the idea that cardiovascular diseases and diabetes with
 aging can be mostly prevented by intervention at the middle-age. A randomized controlled
 trial with repeated measure design will be conducted to examine the effect of 1-year regular
 yoga training on the MetS parameters in middle-aged and older individuals who are 30-60 and
 60-80 years of age, respectively. Primary outcome measures include waist circumference,
 systolic/diastolic blood pressure, blood glucose, triglyceride, and lipid cholesterol profile
 whereas secondary outcome measures include self-reported stress and depression levels. This
 study is anticipated to provide valuable information in exploring the therapeutic role of
 yoga in managing MetS. As yoga exercise is an economical regimen which can be easily and
 readily applied to large scale of target population, it is of hope to be practically useful
 to relieve the burden on cardiovascular disease and diabetes by introducing yoga lifestyle to
 the management of MetS.
Inclusion Criteria:

 MetS is defined as having three or more (>= 3) of the following conditions:

 -  Central obesity - Waist circumference >= 90 cm (Asian male); 80 cm (Asian female)

 -  High blood pressure - Systolic blood pressure/diastolic blood pressure >= 130/85 mmHg
 or use of hypertension drug

 -  Elevated blood glucose - Fasting blood glucose >= 100 mg/dL or use of hyperglycemia
 drug

 -  Elevated blood triglyceride - Blood triglyceride >= 150 mg/dL

 -  Reduced HDL-cholesterol - HDL-C <= 40 mg/dL (male); <= 50 mg/dL (female)

 Exclusion Criteria:

 -  Dementia

 -  Mental disorders

 -  Severe or acute cardiovascular illnesses

 -  Post-stroke,

 -  Neuromusculoskeletal illnesses

 -  Major orthopaedic diagnosis in the lower back

 -  Pelvis or lower extremities

 -  Severe rheumatoid arthritis

 -  Osteoarthritis

 -  Pulmonary illnesses

 -  Immobile

 -  Wheelchair users

 -  Undertaking drug therapy treating metabolic abnormalities

 -  Acute medical illness

 -  Symptomatic heart disease

 -  Symptomatic lung disease

 -  Physical conditions not suitable for exercise training, and tobacco users

 -  Regular physical activities (>= 3 days per week of moderate exercise intensity >= 30
 minutes)