The Efficacy of Si-Ni-Tang (a Chinese Herbal Formula) for Severe Sepsis
The Efficacy of Si-Ni-Tang (a Chinese Herbal Formula) for Severe Sepsis
The purpose of this study is to evaluate the efficacy of Si-Ni-Tang (a Chinese Herbal Formula
 documented in Shang Han Lun) in treating severe sepsis.
Inclusion Criteria:

 -  Severe sepsis (according to American college of chest Physicians/ Society of Critical
 Care Medicine (ACCP/SCCM) criteria)

 -  Informed consent provided by patients or legally authorized representative

 -  Yin syndrome in syndrome differentiation (according to principles of traditional
 Chinese medicine (TCM) syndrome differentiation)

 Exclusion Criteria:

 -  Pregnant or nursing female

 -  Subject receiving immunosuppressive or immunoenhancement therapy in the past 3 months

 -  Patients with known or suspicious autoimmune diseases

 -  Patients not expected to survive 28 days due to end-stage disease or other
 uncorrectable medical condition

 -  Fasting subjects

 -  Known or suspicious allergy to any ingredient of Si-Ni-Tang

 -  Patients not expected to survive 5 days for various reasons