Cluster Headache, Addictions and Vascular Function
Cluster Headache, Addictions and Vascular Function
Cluster headache (CH) is one of the most painful primitive headaches. Developments in
 neuroimaging have demonstrated activation of the ipsilateral hypothalamic and orexinergic
 system, which is similar in patients with addictions. CH has strong links to the vascular
 system but there is no study measuring endothelial function in CH sufferers.
Several studies have shown an association between Cluster headache (CH) and smoking. However,
 no data exists on the link between CH and other addictions, and impact of these addictions on
 clinical characteristics of the disease. In addition, despite the strong biological link
 between CH and the vascular system, systematic investigations about vascular functions in CH
 patients are lacking.

 This will be a prospective cohort study of 150 patients with CH, conducted in the Headache
 Center in Bordeaux, France.
Inclusion Criteria:

 -  Presenting a chronic or episodic cluster headache diagnosed according to the
 International Classification of Headache Disorders (ICH-D III) criteria, in active or
 inactive phase.

 Exclusion Criteria:

 -  Other primary headaches

 -  Subjects without social insurance