Non-invasive Method for Predicting the Presence of Gastroesophageal Varices in Patients With Cirrhosis
Non-invasive Method for Predicting the Presence of Gastroesophageal Varices in Patients With Cirrhosis
Gastroesophageal varices are a complication of portal hypertension in cirrhosis.Endoscopy is
 an unsatisfactory screening test.In this prospective clinical study,we will enroll patients
 with cirrhosis of various causes, all of whom undergo laboratory tests, elastography, and
 serum proteomic differential protein testing, including liver elastography (LSM) and spleen
 elastography (SSM). Baveno VI or expanded BavenoVI criteria are validated by comparing
 patients' LSM, SSM, serum differential protein, platelet count, and EGD data to evaluate the
 clinical value of SSM and differential proteins in excluding cirrhosis of cirrhosis.At the
 same time, based on SSM and serum differential protein, a new predictive model of variceal
 varices will be established to evaluate the diagnostic value of SSM and differential protein
 for esophagogastric varices, and a non-invasive method for reliably predicting and evaluating
 cirrhosis with esophageal varices will be found.
Inclusion Criteria:

 1. The age ranged from 18 to 75 years.

 2. Clinical or pathological diagnosis of cirrhosis;

 3. Electronic gastroscopy is planned;

 4. To agree and sign the informed consent;

 Exclusion Criteria:

 1. Hepatocellular carcinoma or other malignant tumors have been or are currently
 diagnosed;

 2. Orthotopic liver transplantation patients;

 3. Patients who have undergone transjugular intrahepatic portosystemic shunt (TIPS),or
 previous surgical shunt;

 4. Pregnant women;

 5. Neurological or psychiatric disorders;