Study to Proof the Clinical and Bacteriological Non-inferiority of Ampicillin/Amoxicillin Versus Moxifloxacin in Hospitalized Patients With Non-severe Community-acquired Pneumonia
Study to Proof the Clinical and Bacteriological Non-inferiority of Ampicillin/Amoxicillin Versus Moxifloxacin in Hospitalized Patients With Non-severe Community-acquired Pneumonia
The purpose of this study is to prove the clinical and bacteriological non-inferiority of
 ampicillin/amoxicillin versus moxifloxacin in hospitalized patients with non-severe
 community-acquired pneumonia.
Inclusion Criteria:

 -  Men or women older than 18 years with signed informed consent

 -  Women in a childbearing age with sufficient conception protection or if necessary
 negative pregnancy test

 -  Infiltrates appeared newly in the x-ray thorax

 -  Breath-conditioned chest pain

 -  At least two of the following clinical symptoms of a pneumonia:

 -  cough which is newly appeared or increasing,

 -  dyspnea

 -  mucopurulent or purulent sputum,

 -  fever (body temperature >= 37.8 degrees Celsius auricalary and/or >= 38,3°C
 rectal), positive auscultation

 -  Negative legionella antigen test in the urine

 -  CRB-65-Index < 3

 Exclusion Criteria:

 -  Hospitalization within the last 28 days (except for the last 72 h)

 -  Participation in another therapy study within the last 4 weeks with studies admission

 -  intake of an antibiotic longer than 24 hrs within the last 72 hours before studies
 admission

 -  Patients in the pregnancy and nursing phase

 -  Existence of contraindications opposite the examining preparations or other B-Lactam
 antibiotics or fluorochinolons

 -  Patients with a CURB-Index >= 3

 -  Patients with suspicion of retrostenotic Pneumonia because of bronchial obstruction

 -  Patients with suspicion of nosocomial Pneumonia

 -  Patients with an infection by a known or suspected resistant pathogene