Extent of Surgical Trauma in Open and Laparoscopic Cholecystectomy
Extent of Surgical Trauma in Open and Laparoscopic Cholecystectomy
The aim of this work is to evaluate which of the two types of operation (traditional/open and
 laparoscopic) has more impact on patients who were operated electively due to their chronic
 calculous cholecystitis.
The prospective, single center, randomized study includes 120 patients who are operated
 electively - 60 patients operated laparoscopically and 60 patients operated traditionally.
 Biohumoral and endocrine parameters of response to trauma are determined from 24 hour urine
 and blood: adrenalin, noradrenalin, metabolites of corticosteroid hormone - 17- hydroxyl and
 17- keto steroid (HPLC method), C reactive protein and albumin, glycemia, creatine
 phosphokinase, lactate dehydrogenase, sedimentation of erythrocytes and serum concentration
 of potassium.
Inclusion Criteria:

 -  Chronic Calculous Cholecystitis

 Exclusion Criteria:

 -  Previous Biliary Surgery

 -  Cholangitis

 -  Obstructive jaundice