Omega 3 in Intervention Spinal Cord Injured People
Omega 3 in Intervention Spinal Cord Injured People
The objective of this study is to evaluate the effect of omega 3 fatty acid on neurological
 recovery, lipid profile and Antioxidant system in patients with spinal cord injury. One
 hundred spinal cord injured patients who come to clinic of spinal injury repair research
 center selected. Then the patients will receive two supplements capsules of omega 3 (600 mg)
 in the intervention group and placebo in the control group. Primary outcome measures are
 professionals evaluation of neurological function by using :

 -  ASIA scale for sensory and motor function

 -  FIM scale for Functional potential

 -  FAM

 -  SF_36 for quality of life

 Lipid profile and Antioxidant profile evaluation by using:

 -  FBS

 -  2hpp

 -  Insulin

 -  LDL

 -  Total cHOL

 -  TG

 -  HDL

 -  Leptin Adiponectin -Calcium-

 -  25OHD

 -  PTH,LH, FSH, Prolactin,Testosterone in males Bone markers by serum levels of
 :Osteocalcin-Osteoprotegrin_Bone Specified ALP- CTX - RANKL

 -  BMD
All no neurological evaluation will be done by experiment researcher under considering of a
 neurologist.All Sub clinical evaluation will be done by specific, sensitive and valid
 laboratory methods. Intervention time will be 14 months.Comparison of these variables will be
 done before and after intervention.
Inclusion Criteria: no metabolic, malignant or kidney disorder, normal TSH, LH, FSH,
 prolactin, and testosterone in men and normal prolactin, estradiol, LH, FSH, and TSH in
 women

 Exclusion Criteria:

 -  pregnancy, lactation, presence of bone disease,hypersensitivity to fish or fish oil,
 hypertension