Anti-adhesive Effect and Safety of "Thermo-sensitive Adhesion Barrier (MEDICLORE)"
Anti-adhesive Effect and Safety of "Thermo-sensitive Adhesion Barrier (MEDICLORE)"
One of most important complication of thyroid surgery is adhesion. There are many
 anti-adhesive materials, but none of them showed significant outcomes. The investigators
 planned double blind prospective study of "Thermo-sensitive Adhesion Barrier (MEDICLORE)" to
 reveal anti-adhesive effect of MEDICLORE. The investigators will recruit total 90 patients
 (control group 45, experimental group 45) and compare postoperative outcomes about adhesion.
Inclusion Criteria:

 -  planned to perform thyroidectomy due to thyroid nodule

 -  no evidence of distant metastasis or invasion to adjacent organ in thyroid cancer

 -  normal preoperative vocal cord movement

 -  normal preoperative laboratory study

 Exclusion Criteria:

 -  uncontrolled hypertension, diabetes, chronic renal failure, coagulopathy

 -  history of keloid or hypertrophic scar

 -  Graves disease or hashimoto thyroiditis patients

 -  aspirin or anticoagulant medication within 7 days

 -  radiation exposure to the head and neck

 -  previous operation to the neck

 -  history of allergic reaction to drugs

 -  pregnant women