From ACute To Chronic Postoperative Pain in Patients for Elective Cholecystectomy
From ACute To Chronic Postoperative Pain in Patients for Elective Cholecystectomy
Chronic Pain is a wellknown complication after cholecystectomy. Intensity of the pain in the
 first week after the operation is a predictive factor for the development of chronic pain,
 but it is unknown whether the risk is more related to one of the different components of
 acute pain (ie somatic, visceral, referred). Furthermore the chronic pain has not been
 systematically described in terms of type of pain or sensory abnormalities etc. (allodynia,
 hyperalgesia etc.).

 The purpose of the study is to examine whether intensity of components of acute pain is
 predictive for development of chronic pain after cholecystectomy and to characterize the
 chronic pain by quantitative sensory testing.

 DNA-samples are collected to examine genetical factors, important for perception of pain, and
 the development of chronic pain.
Inclusion Criteria:

 -  Patients for elective cholecystectomy

 -  18 years or older at the day of the operation

 -  Capable of speaking, reading and writing danish

 Exclusion Criteria:

 -  Previous abdominal operation

 -  Patients with preoperative neuropathies

 -  Patients with other diseases in the nervous system, preoperative paresthesias or other
 sensory disturbances.