T-EUS for Gastrointestinal Disorders: A Multicenter Registry
T-EUS for Gastrointestinal Disorders: A Multicenter Registry
The purpose of this registry is to record information and evaluate the impact of Endoscopic
 Ultrasound (EUS) Guided Endoscopic retrograde cholangiopancreatography (ERCP) on the
 management of pancreatico-biliary disorders. The registry will evaluate efficacy, safety and
 technical success of the Endoscopic Ultrasound (EUS)Guided Endoscopic retrograde
 cholangiopancreatography (ERCP) procedures. The safety and efficacy of various EUS-Guided
 ERCP procedures have been assessed in a series of studies.

 This multi-center registry has been initiated:

 -  To document the impact of EUS-Guided ERCP procedures on the management of
 pancreatico-biliary disorders including malignancies.

 -  To assess the clinical and technical success rates of EUS-Guided ERCPs for diagnostic or
 therapeutic procedures.

 Design is retrospective and prospective registry study.

 Procedures that will be captured include:

 1. EUS-Coils placement

 2. EUS Glue injection

 3. EUS-Fiducial placement

 4. EUS-Neurolysis

 5. EUS-Stent placement

 6. EUS-alcohol injection

 7. EUS-fluid collection, abscess or cavity drainage

 8. EUS guided ductal drainage

 9. EUS-guided Ablation

 10. EUS-guided anastomosis 11. EUS Guided ERCP for gallbladder, pancreatic duct or biliary
 duct drainage
Endoscopic Ultrasound (EUS) Guided Endoscopic retrograde cholangiopancreatography (ERCP) has
 become a therapeutic intervention for the management of biliary obstruction or pancreatic
 strictures related to chronic pancreatitis or other diseases. Successful biliary or
 pancreatic cannulation can be achieved in 90 to 97%. Failure to obtain biliary access can be
 related to operator experience, peri-ampullary diverticula, prior surgery (e.g., Billroth II
 anatomy), tumor involvement of the ampulla, biliary sphincter stenosis and impacted stones.
 In experienced hands, pancreatic duct cannulation fails in less than 10% of cases. This is
 primarily related to surgically altered anatomy or inflammation. Referral to a tertiary care
 center , percutaneous intrahepatic cholangiography (PTC) for biliary decompression , and
 surgical intervention are typically offered after a failed ERCP. Percutaneous intrahepatic
 cholangiography with subsequent percutaneous or endoscopic drainage has a morbidity of up to
 32%. Surgery can also be associated with significant morbidity and mortality.

 Endoscopic ultrasound (EUS) allows detailed imaging of the regional anatomy by approximating
 the frequency transducer to the region of interest. With the evolution of linear array and
 the ability to direct a needle within the field of interest, the therapeutic potential of EUS
 has reached new levels beyond fine needle aspiration (FNA), celiac plexus blocks and drainage
 of cystic lesions. The biliary and pancreatic systems, being in close proximity to the
 gastric or duodenal lumen, are a logical target for EUS in cases not accessible by ERCP.
 EUS-assisted cholangiopancreatography was described a decade ago. In order to validate these
 procedures and broaden its use beyond tertiary centers, it is crucial to understand its
 efficacy and success rate. The objective of the study is to evaluate retrospectively and
 prospectively the efficacy and safety of EUS-Guided ERCP procedures for the diagnosis and
 treatment of pancreatico-biliary disorders.

 The purpose of this registry is to record information and evaluate the impact of EUS-Guided
 ERCP on the management of pancreatico-biliary disorders. The registry will evaluate efficacy,
 safety and technical success of the EUS-Guided ERCP procedures.

 The involvement of multi-international sites is crucial- as the advanced endoscopists outside
 US are attempting similar complex EUS-Guided ERCPs for complicated pancreatico-biliary cases
 as their counterparts in US. However, because of the non-existence of a registry, these cases
 are often reported as isolated case series with remarkable technical similarities to case
 series in other countries.

 The registry hopes to combine all such comparable cases and collect enough relevant data for
 statistical analyses.
Inclusion Criteria:

 -  Any patient who has undergone EUS-guided ERCP (Endoscopic Retrograde
 Cholangiopancreatography)for diagnosis or treatment of a pancreatico-biliary disorder.

 -  Above 18 years of age.

 Exclusion Criteria:

 -  Any subject who has not undergone Endoscopic Ultrasound (EUS) guided Endoscopic
 retrograde cholangiopancreatography (ERCP).

 -  Below 18 years of age.