The Effects of Auditory Cueing on Rhythmic Movement and Cortical Excitability in Patients With Parkinson's Disease
The Effects of Auditory Cueing on Rhythmic Movement and Cortical Excitability in Patients With Parkinson's Disease
Parkinson's disease (PD) is a progressive degenerative disease of central nervous systems
 deficit. The clinical symptoms of Parkinson's disease include the following motor tasks:
 difficult in initiating movement, performing rhythmic movement or serial movement, the
 ability of learning motor movement is also affected. The primary treatment for Parkinson's
 disease is medical treatment; surgery is used if in need. Rehabilitation such as physical
 therapy, which aims to improve patient's quality of life and functions, is a non-invasive
 treatment and value for PD patients. Auditory cue is a technique that widely applied on
 training patients with Parkinson's disease, and some researches revealed that auditory cueing
 could improve motor performance. However, the mechanism under this treatment technique is
 still unknown.

 This study is to investigate the effect of auditory cueing on rhythmic finger movement in
 patients with Parkinson's disease. To investigate the mechanism under auditory cueing,
 neurophysiological data such as motor cortex excitability and blood flow in cortical cortex
 will be obtained by using Transcranial magnetic stimulation (TMS) and near infrared
 spectroscopy (NIRS).
Inclusion Criteria:

 -  Clinical diagnosis of Parkinson disease

 Exclusion Criteria:

 -  Clinical diagnosis of other neurological diseases

 -  Dementia

 -  Been diagnosed with any mental illness

 -  History of seizures

 -  Brain trauma

 -  Body with a pacemaker or other electrical stimulator

 -  Pregnancy