Proteomics and Radiomics Research of Breast Cancer Markers in Tissue, Interstitial Fluid and Serum
Proteomics and Radiomics Research of Breast Cancer Markers in Tissue, Interstitial Fluid and Serum
The current study is a case control study involving comparisons of tissue interstitial fluid
 from breast cancer and adjacent non-cancerous tissue as well as that from benign breast
 lesion and its adjacent non-diseased tissue for a distinguishable breast cancer profile. The
 purpose of this research is to collect fresh breast nodule/cancer and surrounding
 non-cancerous tissue for proteomic studies of the interstitial fluid to identify a profile
 distinguishing breast cancer which will also permit future research on stored interstitial
 fluid, blood or tissue samples. Specific markers identified from interstitial fluid study
 will be investigated in blood samples to develop serum markers for breast cancer diagnosis
 and prognosis. Additionally, we will perform both prospective and retrospective research on
 breast cancer involving clinical, demographic, epidemiologic information, treatment,
 follow-up and outcomes on breast nodule/cancer cases collected.
Inclusion Criteria:

 -  All subjects ≥ 18 years of age undergoing surgery for indeterminate breast nodules and
 all subjects with newly diagnosed breast cancer will be eligible to participate.

 Exclusion Criteria:

 -  Anyone < 18 years of age.