Breast MRI Spectroscopy, Department of Defense (DOD)
Breast MRI Spectroscopy, Department of Defense (DOD)
The purpose of this new imaging method is to provide physicians with additional information
 not available with standard imaging methods. This includes information about the make up of
 different breast diseases. Using spectroscopy data, it may be possible to tell the difference
 between benign conditions of the breast from malignant tumors and provide more accurate
 information than can be obtained with regular MRI. Along with the MRI a new method of
 evaluating the images or pictures will be used. This new method is called spectroscopy and is
 used routinely on other parts of the body such as the prostate and brain. Pictures produced
 with this sequence look different than the regular MRI pictures. Performing spectroscopy on a
 1.5T magnet adds another imaging sequence (another scan) to the routine MRI protocol, thus
 increasing exam time (extra 10-15 minutes). This study will enroll patients who are scheduled
 for a Magnetic Resonance Imaging (MRI) examination ordered by their primary physician.
Our aim is to perform MR Spectroscopy (MRS) on 150 patients at the end of their clinically
 indicated routine breast MRI guided biopsy and breast MRI guided needle localization
 examination using a software package from General Electric Medical Systems (Milwaukee,WI).
 This will add time to the routine examination but will not involve additional injections of
 contrast. We will analyze the spectroscopic data to determine if benign lesions can be
 reliably differentiated from malignant ones. The MR Spectroscopy (MRS) will be administered
 at Memorial Sloan Kettering Cancer Center, 1275 York Ave, NY,NY 10021.
Inclusion Criteria:

 -  Patient needs to be ≥ or = to 18 years of age

 -  scheduled for diagnostic breast MRI examination or interventional procedure for a
 suspected or known breast lesion ≥ or = to 1 centimeter

 Exclusion Criteria:

 -  Patients who would be normally excluded from undergoing an MRI examination include:

 -  Patients with a pacemaker, aneurysm clip or any other condition that would warrant
 avoidance of a strong magnetic field

 -  Patients who are pregnant are excluded from participation of this study

 -  Patients who are unable to comply or complete the MRI exam due to claustrophobia or
 high levels of anxiety.

 -  Patients undergoing chemotherapy