Intracranial Pressure During Migraine
Intracranial Pressure During Migraine
An increase in intracranial pressure (ICP) during migraine attacks is possible and could
 contribute to pain initiation and maintenance. From now on, it was not possible to measure
 ICP in a non-invasive way. The development of a new tool allows non-invasive self-measures of
 ICP variations. Thus, it is possible for the first time to look for such ICP variations
 during migraine attacks and to conclude if this mechanism is implied in the pathophysiology
 of migraine.
Womens presenting with regular menstrual migraine treated with triptans will be included in
 the study. Self-measure of ICP will be performed outside and during menstrual migraine
 attacks. The potential variations will be compared to the measures done on matched healthy
 women outside and during menses.
Inclusion Criteria:

 -  18 to 50 non menopausal women

 -  Menstrual migraine

 -  Using a triptan as usual treatment to relieve attacks

 -  Usual triptan efficacy although recurrence is possible

 Exclusion Criteria:

 -  Disease of the ear

 -  Intracranial hypertension

 -  Chronic daily headache

 -  Use of topiramate or acetazolamide

 -  Triptans used more than 10 days/month

 -  Analgesic drug used more than 15 days/month

 -  Uncontrolled high blood pressure

 -  BMI >30

 -  Ongoing allergic rhinitis or flu