Comparison Between Effect of Conventional, Intensive and Light Emitting Diodes (LED) Phototherapy on Oxidative Stress Among Neonates With Unconjugated Hyperbilirubinemia
Comparison Between Effect of Conventional, Intensive and Light Emitting Diodes (LED) Phototherapy on Oxidative Stress Among Neonates With Unconjugated Hyperbilirubinemia
The aim of the present study is to test a hypothesis assuming that phototherapy might have an
 effect on oxidant/antioxidant status in term and late-preterm neonates with unconjugated
 hyperbilirubinemia.
Inclusion Criteria:

 -  Term and late-preterm neonates (≥35weeks) according to the guidelines of the American
 Academy of Pediatrics (2004) which stated that gestational ages of newborns were
 determined according to the first day of the mother's last menstrual period (by the
 mother's statement) and were additionally confirmed by the Ballard scoring system
 (Ballard et al., 1991) and antenatal ultrasonographic estimation or obstetric records
 if present.

 -  Clinical significant indirect hyperbilirubinemia requiring phototherapy in the first
 week of life.

 -  Normal blood counts and peripheral blood smears

 -  Normal reticulocytic count.

 -  Breast fed newborn.

 Exclusion Criteria:

 -  Those in whom the total serum bilirubin (TSB) level rose by more than 5 mg/dl per day
 or was higher than 20 mg/dl within the first 24 hours after birth were excluded from
 the study.

 -  Infant of diabetic mothers.

 -  Maternal eclampsia-preeclampsia.

 -  Birth asphyxia

 -  Sepsis

 -  congenital anomalies.

 -  Direct Coombs'test positive

 -  Pathological causes of hyperbilirubinemia.

 -  Enclosed hemorrhage.

 -  Hemolytic type of hyperbilirubinemia due to blood group or Rh incompatibility.