Family Smoking Cessation in Romania Using Pregnancy as a Window of Opportunity
Family Smoking Cessation in Romania Using Pregnancy as a Window of Opportunity
The purpose of this research is to adapt and implement a pregnancy and postnatal smoking
 cessation intervention for couple that will begin early in pregnancy and have an additional
 postnatal component.
Pregnancy smoking and postnatal relapse are highly prevalent in Romania and Central and
 Eastern Europe, with lifetime negative health effects for the women and their children. There
 are higher odds of female smoking persistence during pregnancy, and of relapse once pregnant
 women quit, when the male partner also smokes.

 Building on ongoing pilot work led by Dr. Meghea with Babes-Bolyai University (BBU) in
 Cluj-Napoca, Romania, the overall objective of the proposed research, conducted through BBU
 in the same target population as the ongoing pilot, is to adapt, enhance, and test the
 implementation feasibility and preliminary efficacy of an evidence-based pregnancy and
 postnatal couple intervention for smoking cessation that begins early in pregnancy and has a
 postnatal component.

 The intervention will be based on the motivation and problem solving (MAPS) approach,
 successful in preventing smoking relapse postpartum in the US, which will be enhanced by
 targeting the couples' smoking behavior by focusing on dyadic efficacy for smoking cessation.
 The target population is primigravida pregnant women and their partners in Cluj-Napoca,
 Romania.

 The specific aims are: (1) To develop an adapted and enhanced couple intervention to reduce
 pregnancy smoking and postpartum relapse in Romania based on the MAPS approach. (2) To
 conduct a pilot randomized controlled trial to test the fidelity of the culturally adapted
 MAPS intervention enhanced for couples smoking prevention during pregnancy and postpartum.
 (3) To examine in the pilot the implementation feasibility and initial efficacy in increasing
 maternal pregnancy smoking cessation and reducing postnatal relapse, with secondary
 hypotheses regarding maternal smoking reduction and spousal cessation, relapse, and
 reduction.

 This study will form the basis for a larger, multicenter clinical trial that will be
 submitted by Dr. Meghea as an R01 application by the end of the 4th year of this award to
 evaluate the effectiveness of the proposed smoking prevention intervention. If proven
 effective in the subsequent R01 trial, the intervention has a high potential for broad
 spectrum population impact and sustainability. The long-term goal is the adoption in the
 national Romanian health system as a proactive extension of the existing STOP SMOKING
 national program which includes a quitline.
Inclusion Criteria:

 -  the woman presents for her first prenatal visit before 14-week gestation,

 -  she is a smoker

 -  18 years or older (legal age for consent and for consuming tobacco in Romania)

 -  married or in a stable relationship

 -  phone service in the home or mobile phone

 -  willing to have the partner contacted for participation, upon brief explanation of the
 study.

 Exclusion Criteria:

 -  partner declines participation upon phone recruitment attempt