Electroacupuncture for Patients With Chronic Urinary Retention Secondary to Lower Motor Neuron Lesion
Electroacupuncture for Patients With Chronic Urinary Retention Secondary to Lower Motor Neuron Lesion
Chronic Urinary Retention (CUR) is defined as a non-painful bladder which remains palpable or
 percussible after the patient has passed urine by International Continence Society. Postvoid
 residual urine volume ≥300 mL seems to be widely accepted.

 CUR may be caused by a variety of diseases and events including injury of sacral plexus,
 cauda equina and sacral spinal cord, pelvic floor nerve lesion after pelvic surgery and
 peripheral neuropathy due to diabetes, etc.. Aforementioned injuries generally affect lower
 motor neuron causing detrusor underactivity, acontractile detrusor or detrusor areflexia. The
 prevalence varies by different causes of lower motor neuron lesion. The symptoms of patients
 are voiding difficulty, bladder distention, bladder without sensation and overflow
 incontinence.

 A multi-center randomized sham-controlled trial will be conducted. The aim of this study is
 to assess the efficacy and safety of electroacupuncture for urinary function of patients with
 CUR caused by lower motor neuron lesion.
Inclusion Criteria:

 -  Have chronic urinary retention caused by lower motor neuron damage.

 -  Age 18 to 75 years.

 -  Have chronic urinary retention caused by injury of sacral plexus, cauda equina and
 sacral spinal cord, pelvic floor nerve lesion after pelvic surgery and peripheral
 neuropathy due to diabetes.

 -  Have postvoid residual urine volume 300 mL or more and sensation of bladder.

 -  Bladder contractile index is more than 100 or more.

 -  Duration of disease is more than 3 months.

 -  Intermittent clean catheterization or indwelling catheterization.

 -  Sign informed consent and participate in the study voluntarily.

 -  Exclusion Criteria:

 -  Have urinary retention due to bladder outlet obstruction (bladder neck contracture,
 urethral stricture, prostate cancer, prostatic hyperplasia, etc.)

 -  Have urinary system tumors or stones.

 -  Have detrusor underactivity due to other non-lower motor neurogenic disease.

 -  Have bowel and urinary disorder due to lesions or injuries of thoracic spinal cord,
 cervical spinal cord and brain.

 -  After suprapubic cystostomy.

 -  Have heart, liver, kidney, mental disorders or coagulation disorders.

 -  Have been implanted a cardiac pacemaker, sacral nerve stimulation electrode, pudendal
 nerve stimulation electrode, or bladder stimulation electrode.

 -  During pregnancy or in lactation.