Mindfulness and Support Group to Improve Patient and Caregiver Burden in Cirrhosis
Mindfulness and Support Group to Improve Patient and Caregiver Burden in Cirrhosis
Chronic liver disease and cirrhosis pose a huge financial burden to the health care system.
 This includes the cost of medical care, employment, disability-related issues and reduced
 survival. Specifically, the complication of cirrhosis known as hepatic encephalopathy (HE)
 especially hinders quality of life, the performance of activities of daily living and the
 ability to drive a motor vehicle in affected subjects. The hidden burden to family members
 and caregivers of these subjects, however, has been all but ignored to date. Evaluation of
 family members and caregivers is essential. The burden of caring for someone with liver
 disease can result in added cost for health care for family members and caregivers and is
 typically not recognized. The importance of the burden to families and family members or
 caregivers resulting from other neurological diseases such as Alzheimer's has been well
 evaluated and specific strategies to educate and counsel family members and caregivers have
 been elaborated. This is important because as the findings of this study have emerged, we
 have found that both Veterans and non-Veterans with cirrhosis and HE have a poor quality of
 life, worse socio-economic status and place a significantly higher burden on their family
 members or caregivers than those without HE
The initial intake visit will include an overall assessment of the situation with the subject
 and family members or caregivers by the study physician and description of the group therapy.
 If the subjects and family members or caregivers want to continue, they will be asked to
 visit with the psychologist individually (subject first, then family member or caregiver,
 then both) in order to confirm their insight into the disease process and assess their
 readiness and appropriateness for the group therapy.

 All concerns regarding confidentiality and details to be discussed during the group therapy
 sessions will be reiterated to subjects and family members or caregivers individually. They
 can then choose to participate or not. If they choose not to participate, they will be seen
 in 1- 3 months to complete the all tests / questionnaires detailed as in the measurements
 section

 Subjects and family members or caregivers agreeing to participate in group therapy will be
 required to attend four weekly group therapy sessions in order for them to be considered as
 group therapy recipients. If they choose to terminate the group at any time, they will be
 free to do so and will be asked to complete all tests / questionnaires detailed as in the
 measurements section

 GROUP INTERVENTION FORMAT:

 Group therapy sessions will be conducted on a weekly basis over a four week period. The group
 therapy sessions will last approximately one hour. The group will not have a rolling
 admission meaning members will be required to attend all scheduled group sessions.

 Measurements used:

 -  QOL assessment using Sickness Impact Profile (a 136 item questionnaire)

 -  Sleep assessment using Pittsburgh Sleep Quality Questionnaire (PQSI) and Epworth
 Sleepiness Scale (ESS)

 -  Assessment of Depression and Anxiety using the Beck Questionnaires

 Structure of the Groups:

 Each group will begin with a review of what was learned in the group before and a review of
 the concrete goals/homework that the participants set from the last group. The group can work
 together to identify barriers and strategies.

 Second portion of the group will focus on acquiring specific skills. These skills include
 Qigong (gentle movements), body scan, progressive relaxation, and loving-kindness meditation
 At the conclusion of the session, subjects, family members or caregivers core skills to be
 targeted as detailed below will be evaluated by the psychologists running the group.

 Core Skills to be Targeted:

 I. Stress Management II. Dealing with Depression III. Adjusting to Anxiety IV. Family Health
 and Changes in Roles
Patients

 Inclusion Criteria:

 1. Cirrhosis proven by radiology, endoscopy (esophageal varices present) or biopsy

 2. Able to give informed consent as determined by the study staff

 3. Have a family member or caregiver who lives with them that is willing to participate

 Exclusion Criteria:

 1. Unable to give consent

 2. Active psychosis

 3. Acute suicidal ideation

 4. No identified family member or caregiver

 Caregivers/Family members:

 Inclusion Criteria:

 1. Sharing living space with cirrhotic patient for at least 3 years

 2. Able and willing to participate in the groups

 Exclusion Criteria:

 1. Unfamiliar with patient's routines and does not live in the same space

 2. Unwilling to consent or participate