BPO vs Hibiclens Soap for Surgical Preparation
BPO vs Hibiclens Soap for Surgical Preparation
This is a randomized trial of benzoyl peroxide soap versus Hibiclens soap for surgical
 preparation. The objective is to determine whether benzoyl peroxide soap, commonly available
 in drug stores for over-the-counter acne treatment, is as or more effective than the standard
 surgical preoperative soap, Hibiclens soap (chlorhexidine gluconate), in reducing loads of
 Propionibacteria (Propi) on or under the skin of patients prior to shoulder arthroplasty
 (joint replacement).
Inclusion Criteria:

 -  Male subjects

 -  Subjects scheduled for elective shoulder arthroplasty at the University of Washington
 Medical Center

 -  Subjects between ages 18-89

 Exclusion Criteria:

 -  Subjects who self-report very sensitive skin

 -  Subjects who are sensitive to benzoyl peroxide

 -  Subjects who are allergic to chlorhexidine

 -  Subjects who had recent prior use of antibiotics (or expect to use them prior to
 surgery)

 -  Subjects who had recent use of acne treatment

 -  Subjects who are not fluent in English.