Air Pollution and Daily Mobility of Pregnant Women Identification of Critical Windows of Exposure
Air Pollution and Daily Mobility of Pregnant Women Identification of Critical Windows of Exposure
This study is conducted to assess the role of pregnant women's daily mobility living in the
 Eurometropole of Strasbourg in a context of the existence of environmental exposure
 disparities (PM10, PM2.5, NO2). Furthermore, this study will tend to identify the critical
 windows of exposure and of greater risk of the adverse pregnancy outcomes as low birth weight
 and prematurity.

 A second question addressed in this work is to assess the relationship between the pregnant
 women's socio-economic status and the air pollution exposure (PM10, PM2.5, NO2).taking into
 account the spatio-temporal variations of the exposure as well as the critical windows of
 exposure during pregnancy.

 The present work deals with the following question "how does the combination of environmental
 exposure, socio-economic status and women's daily mobility, could contribute to socio-spatial
 inequalities in the health of the newborn? The underlying hypothesis is that the
 accumulation, in given area, of environmental exposures (as PM10, PM2.5 and NO2), of
 unfavorable living conditions (socio-economic environment) and individual factors (specific
 spatio-temporal trajectory) would induce an increased risk for the health of the newborn,
 (more particularly in terms of birth weight and term of birth). This hypothesis is structured
 4 sub-hypotheses: i) The misclassification of exposure is socially distributed among pregnant
 women living in the Eurometropole of Strasbourg. ii) Beyond maternal and fetal
 characteristics, pregnant women who reside in a more socio-economically deprived neighborhood
 and / or with higher levels of environmental exposure to PM10, PM2.5 and NO2 are more at risk
 of preterm newborn and low birth weight newborn. iii) The accumulation of environmental
 exposures of the pregnant women and their daily mobility over their territory during the
 pregnancy increase the health inequalities of the newborn. iv) The critical windows of fetal
 exposure to pollutants is related to the socioeconomic level of their neighborhood and to the
 daily mobility of the women in their territory during pregnancy. Women are included in the
 study at the time of their first or second trimester ultrasound. Here are the tools used in
 the study: Descriptive survey of their idividuals characteristics, descriptive survey of
 women's mobility to assess their exposure during each trimester of pregnancy.
Inclusion Criteria:

 -  Pregnant women dwelling in the Eurometropole of Strasbourg

 -  Women who have done ultrasound monitoring in the HUS (Hopitaux Universitaires de
 Strasbourg)

 -  Good understanding of the French language

 -  Women who give her signed agreement of non-opposition to research and / or who give
 her signed consent for the data collect

 Non-inclusion criteria:

 -  refusal to participate in the study

 -  under-age women (<18 years old)

 -  women who not have a clear understanding of the information (emergency situation,
 comprehension problems…)

 -  Women must not be under tutorship or curatorship or under the protection of a
 conservator ("sauvegarde de justice")

 Exclusion criteria:

 -  premature delivery threats

 -  placenta previa

 -  twin pregnancy

 -  pre-eclampsia