Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation
Multi-center, global, prospective, non-randomize, interventional, pre-market trial. All
 subjects enrolled with receive the study device
Inclusion Criteria:

 -  moderate to severe or severe symptomatic mitral regurgitation

 -  Local site multidisciplinary heart team experienced in mitral valve therapies agrees
 that the subject may not be optimally treated with approved transcatheter repair or
 conventional mitral valve surgery

 Exclusion Criteria:

 -  prior transcatheter mitral valve procedure with device currently implanted

 -  anatomic contraindications

 -  prohibitive mitral annular calcification

 -  left ventricular ejection fraction <30%

 -  need for emergent or urgent surgery

 -  hemodynamic instability