Pilot Study of Efficacy of Nail Gel in Finger Nail Surface Abnormality
Pilot Study of Efficacy of Nail Gel in Finger Nail Surface Abnormality
Nail surface abnormalities is any conditions that affect the nail matrix or nail bed which
 cause nail plates grow defectively. Common nail surface abnormalities are pitting nails,
 longitudinal ridging, and transverse ridging/Beau's line. Aging nails usually have nail
 surface abnormalities as well.

 Nail gels are artificial nails used widely for aesthetic purposes. Although, their cosmetic
 use is increasing with day by day, their usefulness in conditions such as nail biting,
 brittle nails, and ingrown toe nails has been reported. Moreover, a previous study reported
 the benefits of nail gels in terms of improving nail surface abnormalities like pitting
 nails, trachyonychia, and onychoschizia.

 This study was conducted to evaluate the efficacy of nail gel containing Glycerin which has
 humectant effect and Artemisia Abrotanum extract which has anti-fungal/bacterial activities
 in finger nail surface abnormalities.
Evaluation of nail surface abnormality can be done by using Visiometer® (bioengineering
 measurement) and dermoscope. Both techniques are non-invasive.

 Artemisia Abrotanum extract has been used as ingredient in cosmetic products and its safety
 has been declared. Undesirable events from external using products containing this substance
 have never been reported yet. Nail gel product in this study has been approved as a cosmetic
 product by Food and Drug Administration of Thailand (Thai FDA).
Inclusion Criteria:

 1. Age 18 years old or above

 2. Being diagnosed nail surface abnormalities stably more than 3 months

 Exclusion Criteria:

 1. Having severe or uncontrolled concomitant diseases

 2. Having nail infection

 3. History of manicure within the last 1 month

 4. Use of Biotin or other nail modifying drugs within the previous 3 months

 5. Pregnancy or lactation