Evaluating Right Ventricular (RV) Size and Function Using the Upper Valley RV Algorithm and Novel Imaging Modalities
Evaluating Right Ventricular (RV) Size and Function Using the Upper Valley RV Algorithm and Novel Imaging Modalities
The primary purpose of this study is to evaluate the diagnostic performance of three methods
 for measuring right ventricular size and function including the Philips Novel RV
 quantification technologies (RV Heart Model volumetric analysis and Philips 2D strain) and
 the Upper Valley Right Ventricle Algorithm (UVRV) algorithm as compared to the gold standard
 of volumetric analysis via cardiac magnetic resonance imaging (CMR) in a broad patient
 population.
This is a single-center, blinded, randomized control trial of patients 18-years or older that
 are undergoing CMR as a standard of care at Dartmouth-Hitchcock Medical Center in Lebanon,
 NH. After informed consent is obtained, subjects undergo a study-specific external,
 non-invasive echocardiogram utilizing a special RV focused protocol on the same day of their
 CMR as close to their scheduled CMR as possible to minimize wait time for consented patients.
 The echocardiogram takes approximately an additional 30 minutes of the subject's time.

 De-identified echocardiogram images from each subject will be evaluated by experienced
 echocardiographers using three different methodologies (standard method, Phillips Novel
 technology and the newly developed UVRV algorithm). The methodologies will be compared with
 each other to determine sensitivity, specificity and accuracy.
Inclusion Criteria:

 -  Patient age is over 18 years

 -  Patient is undergoing Cardiac MRI with sequences that permit biventricular volumetric
 analysis

 -  Patient is capable of giving informed consent

 -  The cardiac MRI images are of diagnostic quality to provide accurate RV and LV volumes

 Exclusion Criteria:

 - Patient unable to under echocardiogram