Patient and Partner Perception After Remission of Cushing's Syndrome
Patient and Partner Perception After Remission of Cushing's Syndrome
Hypercortisolism leads to long term physical and cognitive sequelae. This also holds true for
 quality of life, even several years after remission. This altered quality of life, highly
 subjective, is however, badly evaluated by the family of the patient. This could lead to
 misunderstanding, avec worsen the general physical and mental health of the patient. To our
 knowledge, this theoretical difference of perception has never been evaluated up to now.

 The aim of our study is to evaluate the difference of perception of the quality of life and
 body image between patients in remission of hypercortisolism, and their caregivers. Secondary
 objectives will be to evaluate the quality of life of the caregivers, the coping strategies,
 and the depression/anxiety parameters of both the patient and the caregiver. Patients and
 methods: the study is Observative, prospective and non-randomized. Inclusion criteria will be
 patients, aged more than 18, with hypercortisolism in remission for at least 1 year.
 Self-questionnaires on quality of life, body image, coping, depression and anxiety will be
 provided to the patient and his/her caregiver. Fulfilling will be blind between the patient
 and his/her caregiver. Inclusion period will be 12 months.

 Results will be compared between the patient and his/her caregiver. Expected results:
 investigators anticipate that some caregivers will have a different perception of the general
 physical and mental condition as stated by the patient. The first time that the quality of
 life of the caregiver would be also altered.

 This original project might lead to modify the management of Cushing's syndrome, by
 considering both the patient and his/her caregiver on a long term basis after remission.
Introduction: Hypercortisolism leads to long term physical and cognitive sequelae. This also
 holds true for quality of life, even several years after remission. This altered quality of
 life, highly subjective, is however, badly evaluated by the family of the patient. This could
 lead to misunderstanding, avec worsen the general physical and mental health of the patient.
 To our knowledge, this theoretical difference of perception has never been evaluated up to
 now. Aims: The aim of our study is to evaluate the difference of perception of the quality of
 life and body image between patients in remission of hypercortisolism, and their caregivers.
 Secondary objectives will be to evaluate the quality of life of the caregivers, the coping
 strategies, and the depression/anxiety parameters of both the patient and the caregiver.
 Patients and methods: the study is Observative, prospective and non-randomized. Inclusion
 criteria will be patients, aged more than 18, with hypercortisolism in remission for at least
 1 year. Self-questionnaires on quality of life, body image, coping, depression and anxiety
 will be provided to the patient and his/her caregiver. Fulfilling will be blind between the
 patient and his/her caregiver. Inclusion period will be 12 months. Results will be compared
 between the patient and his/her caregiver. Expected results: investigators anticipate that
 some caregivers will have a different perception of the general physical and mental condition
 as stated by the patient. The first time that the quality of life of the caregiver could be
 also altered. Perspectives: This original project might lead to modify the management of
 Cushing's syndrome, by considering both the patient and his/her caregiver on a long term
 basis after remission.
Inclusion Criteria:

 -  Subject, male or female over 18

 -  Subject presenting a hypercortisolism in remission or controlled by a drug treatment
 for more than one year.

 -  Subject with a good understanding of the French language

 -  Non-institutionalized subject

 -  Subject whose informed consent could be obtained

 Exclusion Criteria:

 -  Minor subject or over 80 years

 -  Subject presenting hypercortisolism in remission for more than 20 years

 -  Major cognitive impairment that does not allow answering a questionnaire

 -  Genetic syndrome responsible for hypercortisolism

 -  Mixed adenoma whose corticotropic share is responsible for hypercortisolism

 -  Pituitary carcinoma

 -  Subject refusing to participate in the study

 -  Subject having no close

 -  Subject whose relative refuses to answer the questionnaires