A Pilot Study to Evaluate Ultrasonic Surgical Aspiration as a Treatment Modality for Cervical Dysplasia
A Pilot Study to Evaluate Ultrasonic Surgical Aspiration as a Treatment Modality for Cervical Dysplasia
Ultrasonic surgical aspiration of the cervix may be an effective method of treating cervical
 dysplasia without compromising the integrity of the cervix in reproductive age women.
Women age 18 to 55 years of age with Cervical Intraepithelial Neoplasia 2 or 3 on colposcopy
 with a negative EndoCervical Curettage are enrolled in a pilot study comparing ultrasonic
 surgical aspiration and traditional cervical excision procedure for the treatment of cervical
 dysplasia. In this pilot study, the patients serve as their own control group. Prior to
 receiving the traditional treatment for cervical dysplasia consisting of Cold Knife
 Conization with EndoCervical Curettage, each patient's cervix is treated with ultrasonic
 surgical aspiration. The aspirate is sent to pathology and the results compared with the
 findings from the cervical cone biopsy. The patients then are followed with Liquid-based
 Cytology pap smears every 4 to 6 months until completion of the study enrollment/treatment
 period.
Inclusion Criteria:

 -  cervical intraepithelial neoplasia II or III

 -  negative endocervical curettage

 -  not pregnant

 -  cervical conization is part of treatment plan

 Exclusion Criteria:

 -  positive endocervical curettage

 -  pregnant

 -  medically unable to undergo surgery