Whether Probiotics Use in Neonate and Infant Improve Their Mother's Life Quality
Whether Probiotics Use in Neonate and Infant Improve Their Mother's Life Quality
Postpartum depression and poor quality of life during postpartum were an vital issue in
 recent years. Infant's health condition was thought to be a possible reasons related mother's
 postpartum quality of life, and functional gastrointestinal disorders such as infantile colic
 and regurgitation were common problem during infant period. Previous study revealed that
 probiotics may improve the infant's discomfort caused by functional gastrointestinal
 disorders. Thus, this study aimed to investigate whether probiotics use in neonate and infant
 improve their mother's life quality?
This is single blinded intervention study. The investigators will invite mother to
 participate in the project after giving birth. At week 0, mother who meet the eligibility
 criteria will be randomized in a single-blind study in a 1:1 ratio to probiotics with Vit. D3
 (five drops per day) or Vit. D3 (placebo) (single drop per day) for 90 days. The follow-up
 will be at the 1, 3 and 6 months all the subjects.
<Participants of neonates>

 Inclusion Criteria :

 -  Gestational age more than 37 to less than 41 weeks

 -  Age less than 1 week on entry into the study

 -  Birth weight adequate for gestational age

 -  Apgar score of more than 8 at 10 minutes

 Exclusion Criteria:

 -  Congenital disorders and/or clinical or physical alterations at clinical examination

 -  Antibiotic or probiotic administration before inclusion

 -  Admission to ICU

 <Participants of neonates' mother>

 Inclusion Criteria:

 -  Aged between 20-50 and baby included in our study

 Exclusion Criteria:

 -  Diagnosed as psychiatric disease during antepartum period or before pregnancy