Efficacy of Variable Lidocaine Concentrations in Tumescent Anesthesia for Pain Control During and After Endovenous Laser Procedure; Non-inferiority Trial
Efficacy of Variable Lidocaine Concentrations in Tumescent Anesthesia for Pain Control During and After Endovenous Laser Procedure; Non-inferiority Trial
Endovenous laser treatment is a minimally invasive procedure that has been shown to be a safe
 and effective treatment for varicose veins. Essential to the successful ablation of refluxing
 veins by endovenous laser treatment is the use of tumescent anesthesia. One of the components
 of tumescent anesthesia is lidocaine, a commonly used local anesthetic. While lidocaine can
 be used safely as long as serum concentrations remain low, its use carries the risk of
 lidocaine toxicity. In order to minimize the risk of lidocaine toxicity it is desirable to
 use the minimum effective concentration of lidocaine needed to manage pain during a
 procedure. This study seeks to determine if a ¼ lower concentration of lidocaine in tumescent
 anesthesia will function as well as the standard dose for pain management in endovenous laser
 treatments. If we find that this is the case, we will be able to reduce the risk of lidocaine
 toxicity in patients undergoing endovenous laser treatment, while maintaining their comfort
 throughout the procedure. This will be achieved through a direct comparison of intra- and
 post-operative pain for patients randomized to receive either the ¼ tumescent lidocaine
 concentration or the standard lidocaine concentration.
Inclusion Criteria:

 -  Large Saphenous Vein treatment

 -  16-85 years old, good health

 -  Able to understand informed consent

 -  Eligible for EVLT determined by physician

 Exclusion Criteria:

 -  Patients with know lidocaine sensitivity

 -  Bleeding disorders

 -  Pregnancy

 -  Congestive heart failure

 -  Liver dysfunction

 -  Patient ineligible for EVLT