Efficacy and Safety of Sublingual Immunotherapy (SLIT)
Efficacy and Safety of Sublingual Immunotherapy (SLIT)
The purpose of this study is to evaluate the efficacy and safety of specific sublingual
 immunotherapy (SLIT) with allergen extracts in patients suffering from seasonal allergic
 rhinitis .
Inclusion Criteria:

 -  Positive history of allergen specific seasonal allergic rhinitis

 -  Positive screening skin prick test (wheal diameter > 3 mm)

 -  Compliance and ability of the patient to complete a Diary Card for self-evaluating of
 the symptoms and antisymptomatic medication

 -  Signed and dated patient´s Informed Consent,

 Exclusion Criteria:

 -  Previous immunotherapy within the last 3 years,

 -  Simultaneous participation in other clinical trials,

 -  Other reasons contra-indicating an inclusion into the trial according to the
 investigator´s estimation (e.g. poor compliance),

 -  Auto-immune disorders,

 -  Severe chronic inflammatory diseases,

 -  Malignancy,

 -  Alcohol abuse,

 -  Existing or intended pregnancy, lactation and/or lack of adequate contraceptive
 protection,

 -  Treatment with beta-blockers (incl. local application) and/or other contra-indicated
 drugs.