A Comparison of Solid and Soluble Forms of Cold and Influenza Remedies
A Comparison of Solid and Soluble Forms of Cold and Influenza Remedies
The study is designed to investigate whether paracetamol from a hot remedy reaches the plasma
 faster than standard paracetamol tablets. The study will also assess the gastrointestinal
 transit of two oral cold and influenza ('flu') formulations using gamma scintigraphy. It is
 postulated that paracetamol in solution, such as from cold and 'flu' hot remedies, provides a
 greater early exposure compared to standard paracetamol tablets. In addition, the
 pharmacokinetic (PK) profile of paracetamol in the two formulations will be investigated.
-  Healthy male volunteers

 -  Body mass index between 18.0-29.9 kg/m^2