Vitamin D Supplementation for Bipolar Depression
Vitamin D Supplementation for Bipolar Depression
The purpose of this study is to whether vitamin d supplementation in those with low levels
 may reduce depression symptoms in people experiencing bipolar depression.
Inclusion Criteria:

 -  Adults >18years old

 -  Bipolar disorder (I,II or NOS),

 -  MADRS Score>7 (mild),

 -  25(OH)D level <30ng/ml (insufficient).

 -  able to take the prescribed vitamin D by mouth

 Exclusion Criteria:

 Systemic diseases such as:

 -  liver and kidney diseases,

 -  known parathyroid disorder,

 -  disorders of vitamin D metabolism,

 -  taking vitamin D replacement therapy,

 -  fat digestion disorder,

 -  diabetes mellitus,

 -  gi surgery

 -  If the serum calcium in the range 2.50-2.55 mmol L, inclusion required a serum PTH
 below 5.0 pmol L-acute psychiatric urgency:

 -  active suicidality,

 -  acute psychosis,

 -  active substance use<6mo or

 -  pregnant or nursing females