Clinical and Laboratory Assessment of Iron Overload in Sickle Cell Anemia and Sickle Cell Thalassemia
Clinical and Laboratory Assessment of Iron Overload in Sickle Cell Anemia and Sickle Cell Thalassemia
Iron overload is well study in Thalassemia patients and it's not only related to blood
 transfusions, since intestinal iron absorption is also increased in those patients. Sickle
 cell patients didn't developed significant clinical symptoms and signs of iron overload in
 spite frequent transfusions. The purpose of this study is to assess the iron overload in
 Sickle cell anemia and Sickle cell Thalassemia patients using clinical parameters and
 laboratory studies including Non Transferrin Binding Iron, Labile Iron and Hepcidin, in order
 to determine the cardiac and liver iron.
Inclusion Criteria:

 -  All the patients with Sickle Cell Anemia and Sickle Cell Thalassemia that are treated
 and followed up at the Pediatric Hematology Unit.