An Observational Study on the Natural Course of Chronic Pancreatitis
An Observational Study on the Natural Course of Chronic Pancreatitis
To explore the impact on genetic and environmental factors for clinical manifestation, and
 the progression of chronic pancreatitis, including development of pancreatic insufficiency
 and other complications.
The present study was an observational study aimed to explore the impact of genetic factors
 (rare pathogenic variants of CP) and environmental factors(smoking and alcohol assumption) on
 the clinical manifestation and progression of CP. The observation items included the pain
 patterns, incidence of complications of CP, pancreatic cancer and death.
Inclusion Criteria:

 -  patients with a diagnosis of chronic pancreatitis

 -  agree to join the study and provide informed consent

 Exclusion Criteria:

 -  autoimmune pancreatitis

 -  pancreatic cancer diagnosed within 2 years after the diagnosis of chronic pancreatitis

 -  the follow-up time less than 3 years