A Randomized Clinical Trial for Depressed Mothers at Primary Care Level
A Randomized Clinical Trial for Depressed Mothers at Primary Care Level
A randomized clinical trial was carried out at primary care level in Santiago, Chile to
 compare a pharmacological intervention for depressed mothers controlled by phone from a
 central level (TM) and the usual treatment (TH) and its impact on children's mental health.

 Hypothesis: pharmacological intervention for depression controlled by phone from a central
 level will be more effective than usual care in depressed mothers.
Aim:to compare a pharmacological intervention for depressed mothers controlled by phone from
 a central level (TM) and the usual treatment (TH) and its impact on children's mental health.

 Material and methods: A RCT wasw carried out at primary care clinics in Santiago.Sample:three
 hundred and forty five depressed women . One children of each mother was randomly selected.
 Women are randomly assigned to receive the usual therapy or a pharmacological intervention
 with periodical telephone contacts with medical collaboration personnel, to reinforce
 compliance with treatment and educate about the disease, for 6 months. Women were blindly
 evaluated at 3, 6 and 12 months with the Hamilton depression rating score (HDRS) and the
 SF-36 to assess depressive symptoms and quality of life, respectively; the Dyadic Adjustment
 Scale to assess marital adjustment.

 Child psychopathology was assessed with the Child Behavior Checklist (CBCL), the Brief
 Psychiatric Rating Scale for Children (BPRS-C), Screen for Child Anxiety Related Emotional
 Disorders(SCARED)and the Children's Depression Inventory.
Inclusion Criteria:

 -  depressed mothers with al least one child aged 6-16

 Exclusion Criteria:

 -  currently treatment for depression,psychosis,bipolar depression,alcohol or drug abuse,
 gravidity.