Amargosa is an unincorporated community and census-designated place in Jim Wells County, Texas, United States. Its population was 291 as of the 2010 census. Prior to 2010, the community was grouped with nearby Owl Ranch as part of the Owl Ranch-Amargosa census-designated place. The community is named for the Amargosa Creek that runs nearby. The word "amargosa" means "bitter" in Spanish.
Amargosa is not an official city or town.