The 2012 Amstel Curaçao Race took place on 3 November 2012. It was the 11th edition of the Amstel Curaçao Race. The race was held on Curaçao, an island off the Venezuelan coast and spanned 73.6 km . It was the only road bicycle race in which men and women competed against each other in the same race.
The 2012 Amstel Curaçao Race took place in cold and rainy weather.