Miyahuaxochtzin of Tiliuhcan was a Queen of Tenochtitlan as a wife of King Huitzilihuitl. She was a daughter of King Tlacacuitlahuatzin and sister of Princess Matlalxochtzin and Queen Tlacochcuetzin. She was the mother of Prince Huehue Zaca and aunt of Princes Cahualtzin, Tetlepanquetzatzin, Tecatlapohuatzin, Coauoxtli and Oquetzal. She was also a grandmother of the King Huitzilatzin.
Prince Huehue Zaca's mother was a Queen