Rafael Caro Quintero (born October 3, 1952) is a Mexican drug trafficker who founded the now-disintegrated Guadalajara Cartel with Miguel Ángel Félix Gallardo and other drug traffickers in the 1970s. He is the brother of fellow drug trafficker Miguel Caro Quintero, the founder and former leader of the extinct Sonora Cartel who remains incarcerated.
Quintero was incarcerated for illegal acts