text:
SARAH (SARAI).
By: Emil G. Hirsch, Wilhelm Bacher, Jacob Zallel Lauterbach, Joseph Jacobs, Mary W. Montgomery
Named Iscah.
In Pharaoh's Harem.
Relations with Hagar.
Died at Thought of the Sacrifice of Isaac.
Repetitions in the Narrative.
Views as to Historical Character.
Eponym Theory.
Her Beauty.
—In Arabic Literature:
Wife of Abraham, who for a long period remained childless (Gen. xi. 29-30). She accompanied her husband from Haran to Canaan (ib. xii. 5). Driven by famine to take refuge in Egypt, Abraham, fearing that her beauty would put his life in danger if their true relations became known, proposed that she pass as his sister. As he had apprehended, she was actually taken by Pharaoh, to whom her personal charms had been highly praised (ib. xii. 10 et seq.), while Abraham was richly dowered by the monarch on her account. But, visited by troubles, Pharaoh began to suspect the truth; and, censuring Abraham, he bade him take his wife and depart.
Sarai being still childless, she induced her husband to take her Egyptian handmaid Hagar for a concubine, that through her she might be "built up," Hagar, feeling herself quick with child, despised her mistress, whereupon Sarai bitterly upbraided her husband. Wishing not to be involved in the quarrel, Abraham told her to do with her handmaid as she deemed best, and Hagar was soon compelled to flee by the harsh treatment accorded her; but an angel, announcing that her seed would be numerous, urged her to return to Sarah (ib. xvi.). After Hagar had borne Ishmael, God told Abraham, whose name hitherto had been Abram, to change Sarai's name to "Sarah," announcing that she would bear him a son. Incredulous on account of Sarah's age (she was ninety), Abraham burst into laughter, wherefor the son was to be called "Isaac" (ib. xvii.). Sarah overheard that she was to give birth to a son when, at a subsequent visit of the three messengers on their way to Sodom, the promise was renewed; she, too, was incredulous, and laughed inwardly, but when interrogated denied that she had laughed (ib. xviii.).
Abraham next removed to Gerar, where Sarah had an experience with Abimelech similar to the one she had had in Egypt. Abimelech, however, was warned in a dream. Reproved for the wrong done, Abraham justified his and Sarah's statement by the explanation that Sarah was the daughter of his father but not of his mother (ib. xx. 1-12). After this, Sarah bore a son, Isaac, which aroused her to say, "God hath made me to laugh, so that all that hear will laugh with me" (ib. xxi. 1-7). The fact that now she had a son of her own augmented her displeasure with Hagar and Ishmael; and Abraham, at her solicitation, sent both away after God had quieted his scruples (ib. xxi. 10 et seq.). Sarah's death is very briefly recorded as having taken place in Kirjath-arba, or Hebron, when she had attained the age of 127 years. She was buried by Abraham in the cave of Machpelah (ib. xxiii., xxv. 10, xlix. 31). No other reference to Sarah is found in the Hebrew canon, except in Isa. Ii. 2, where the prophet appeals to his hearers to "look unto Abraham your father, and unto Sarah that bare you."
E. G. H.Named Iscah. —In Rabbinical Literature:
Sarah was the niece of Abraham, being the daughter of his brother Haran. She was called also "Iscah" (Gen. xi. 29), because her beauty attracted general attention and admiration (Meg. 14a). She was so beautiful that all other persons seemed apes in comparison (B. B. 58a). Even the hardships of her journey with Abraham did not affect her beauty (Gen. R. xi. 4). According to another explanation, she was called Iscah because she had prophetic vision (Meg. l.c.). She was superior to Abraham in the gift of prophecy (Ex. R. i. 1.). She was the "crown" of her husband; and he obeyed her words because he recognized this superiority on her part (Gen. R. xlvii. 1). She was the only woman whom God deemed worthy to be addressed by Him directly, all the other prophetesses receiving their revelations through angels (ib. xlv. 14). On their journeys Abraham converted the men, and Sarah the women (ib. xxxix. 21). She was called originally "Sarai," i.e., "my princess," because she was the princess of her house and of her tribe; later she was called "Sarah" = "princess," because she was recognized generally as such (Ber. 13a; Gen. R. xlvii. 1).
On the journey to Egypt, Abraham hid his wife in a chest in order that no one might see her. At the frontier the chest had to pass through the hands of certain officials, who insisted on examining its contents in order to determine the amount of duty payable. When it was opened a bright light proceeded from Sarah's beauty. Every one of the officials wished to secure possession of her, each offering a higher sum than his rival (Gen. R. xl. 6;."Sefer ha-Yashar," section "Lek Leka"). When brought before Pharaoh, Sarah said that Abraham was her brother, and the king thereupon bestowed upon the latter many presents and marks of distinction ("Sefer ha-Yashar," l.c.). As a token of his love for Sarah the king deeded his entire property to her, and gave her the land of Goshen as her hereditary possession: for this reason the Israelites subsequently lived in that land (Pirḳe R. El. xxxvi.). He gave her also his own daughter Hagar as slave (ib.). Sarah prayed to God to deliver her from the king, and He thereupon sent an angel, who struck Pharaoh whenever he attempted to touch her. Pharaoh was so astonished at these blows that he spoke kindly to Sarah, who confessed that she was Abraham's wife. The king then ceased to annoy her ("Sefer ha-Yashar," l.c.). According to another version, Pharaoh persisted in annoying her after she had told him that she was a married woman;thereupon the angel struck him so violently that he became ill, and was thereby prevented from continuing to trouble her (Gen. R. xli. 2). According to one tradition it was when Pharaoh saw these miracles wrought in Sarah's behalf that he gave her his daughter Hagar as slave, saying: "It is better that my daughter should be a slave in the house of such a woman than mistress in another house"; Abimelech acted likewise (Gen. R. xlv. 2). Sarah treated Hagar well, and induced women who came to visit her to visit Hagar also. Hagar, when pregnant by Abraham, began to act superciliously toward Sarah, provoking the latter to treat her harshly, to impose heavy work upon her, and even to strike her (ib. xlv. 9).
Sarah was originally destined, like Abraham, to reach the age of 175 years, but forty-eight years of this span of life were taken away from her because she complained of Abraham, blaming him as though the cause that Hagar no longer respected her (R. H. 16b; Gen. R. xlv. 7). Sarah was sterile; but a miracle was vouchsafed to her (Gen. R. xlvii. 3) after her name was changed from "Sarai" to "Sarah" (R. H. 16b). When her youth had been restored and she had given birth to Isaac, the people would not believe in the miracle, saying that the patriarch and his wife had adopted a foundling and pretended that it was their own son. Abraham thereupon invited all the notabilities to a banquet on the day when Isaac was to be weaned. Sarah invited the women also, who brought their infants with them; and on this occasion she gave suck to all the strange children, thus convincing the guests of the miracle (B. M. 87a; comp. Gen. R. liii. 13). Sarah's behavior toward Ishmael, whom she drove away from his father's roof, is justified on the ground that she saw him commit the three greatest sins, namely, idolatry, unchastity, and murder, (ib. liii. 15).
Legends connect Sarah's death with the sacrifice of Isaac (ib. lviii. 5), there being two versions of the story. According to one, Samael came to her and said: "Your old husband seized the boy and sacrificed him. The boy wailed and wept; but he could not escape from his father." Sarah began to cry bitterly, and ultimately died of her grief (Pirḳe R. El. xxxii.). According to the other legend, Satan, disguised as an old man, came to Sarah and told her that Isaac had been sacrificed. She, believing it to be true, cried bitterly, but soon comforted herself with the thought that the sacrifice had been offered at the command of God. She started from Beer-sheba to Hebron, asking every one she met if he knew in which direction Abraham had gone. Then Satan came again in human shape and told her that it was not true that Isaac had been sacrificed, but that he was living and would soon return with his father. Sarah, on hearing this, died of joy at Hebron. Abraham and Isaac returned to their home at Beer-sheba, and, not finding Sarah there, went to Hebron, where they discovered her dead ("Sefer ha-Yashar," section "Wayera"). During Sarah's lifetime her house was always hospitably open, the dough was miraculously increased, a light burned from Friday evening to Friday evening, and a pillar of cloud rested upon the entrance to her tent (Gen. R. lx. 15).
W. B. J. Z. L.—Critical View:
The two forms of the name, "Sarah" and "Sarai," are identical in meaning; it is difficult to understand the reason for the change. "Sarai" is probably the more archaic form of "Sarah," though the termination "ai" is unusual in the feminine. The writer of Gen. xvii. 15 must have considered the "ah" of "Sarah" as implying in some way "yahu" or "yah" (the "Yhwh" element). Accordingly, the change would be similar to that of "Joshua" to "Jehoshua." Perhaps it was the intention to read the name "Sarayahu," the "hu" being added to "Sarai." In that case the meaning "princess" now given to "Sarah" must be abandoned. The element "sarah" is identical with a part of the name "Israel," and "Sarah" and "Sarai" are appropriate names for Israel's mother (Isa. li. 2; comp. Robertson Smith, "Kinship and Marriage," p. 30; for the forms see Olshausen, "Lehrbuch der Hebräischen Sprache," § 110; Nöldeke, in "Z. D M. G." 1886, p. 183; 1888, p. 484; König, "Historisch-Kritisches Lehrgebäude," II. i. 427). The name "Sa-ra-a" is reported to occur in Babylonian tablets (Cheyne and Black, "Encyc. Bibl." iv. 4285, note 3).
The story of Sarah's life, brief and incomplete as it is, presents nevertheless curious repetitions, e.g., the incident with Pharaoh and a similar incident with Abimelech (Gen. xii. 10 et seq. and xx. 1 et seq.). Marriages with half-sisters were, in primitive matriarchy, regarded as anything but incestuous. From the point of view of the history of culture these episodes are very instructive. But it is not very probable that Abraham would have run the risk twice. Moreover, a similar incident is reported in regard to Isaac and Rebecea (ib. xxvi. 6-11). This recurrence indicates that none of the accounts is to be accepted as historical; all three are variations of a theme common to the popular oral histories of the Patriarchs. That women were married in the way here supposed is not to be doubted. The purpose of the story is to extol the heroines as most beautiful and show that the Patriarchs were under the special protection of the Deity. The promise of Isaac and the explanation of the name are given in duplicate. First, Abraham is the recipient of the promise, and he laughs (ib. xvii. 15-21). In the second narrative (ib. xviii.) Abraham again is given the promise, but Sarah laughs. Finally, the name receives a third justification in Sarah's exclamation at his birth (ib. xxi. 6).
According to Pentateuchal analysis, the references to Sarah in Genesis are divided among the various strata as follows:
Gen. xi. 29 belongs to J (Jahvist);
xii. 5, 10-20 to J;
xvi. to J (except la, 3, 15, 16);
xvii. 15-21 to P (Priestly Code);
xviii. to J; xx. to E (Elohist);
xxi. 1a, 2a to J;
xxi. 6, 7 to E;
the remainder to P.
Concerning the kernel of historical fact underlying the patriarchal cycle in Genesis, and thus also the detached glosses concerning Sarai = Sarah, there is no unanimity of opinion among scholars. Theirvarious views may be summarized as follows:
(1) The Patriarchs, including Abraham, so likewise his wives, were historical individuals reports of whose adventures and deeds have come down through long and differing channels of oral tradition. According to the theory which they variously assumed to be worked out in the history of Israel, historiographers whose writings are incorporated in the Pentateuch selected from this mass of discordant material what suited their purpose, and reconstructed even this in accordance with their plans. This accounts for the duplications and discrepancies. According to Baethgen ("Beiträge zur Semitischen Religionsgesch." p. 157), "Sarah" is a simple appellative representing a historical character, whose life is given in fragments and with free embellishments.
(2) The patriarchal cycle represents older Canaanite, pre-Israelitish material, adopted and adapted by Israel. As such, the stories disclose views concerning the relations of septs and clans, as well as concerning political and geographical conditions. Genealogies such as those evolved in the patriarchal story are never of individuals. Tribal antipathies and sympathies, and political and racial interdependence and kinship, are expressed by them; but frequently, in order to complete a system, an individual ancestor or eponym is invented. While some of the names that occur are clearly those of clans, or of localities, Abraham = Abiram is not. It seems to be an appellative; but it is connected with Hebron, an old center. Sarai = Sarah, on the other hand, is the name of a clan—Israel. As Jacob became Israel in another cycle (with Beth-el), so here Abraham (Hebron) is connected with Israel. This is the meaning of the marriage of Abraham with Sarah, as similar ethnic or historical data underlie the story of his dealings with Hagar and Keturah.
(3) These Patriarchs are regarded by most members of the critical school as the outcome of culture-evolution. That matriarchy once prevailed, that blood-relationship was traced only through the mother, that marriage by capture or purchase was the rule, form probably the historical kernel involved in the repeated narratives of Sarai's marital adventures with men other than Abraham. On the other hand, her dealings with Hagar illustrate the conditions obtaining in the polygamous households of the sheiks of the time and country. The persons are free inventions; the conditions are not.
(4) Originally, Canaanite local eponyms connected with Israel; the Patriarchs were later ranged and ranked systematically, so as to establish an exclusive descent for Israel and disclose its distinction as the people of Yhwh. In this scheme Abraham becomes the "great ancestor" (Abram), or "the ancestor of many nations." Through his wife Sarah he begets the Isaac-Jacob tribes, or Israel (= Sarah); and through his concubine Hagar he begets Ishmael, who therefore is marked as lesser in her degree of purity.
(5) The development of religion is typified in these ancestral figures. Abraham and Sarah represent a sort of elementary monotheism, a religion standing midway between pure Mosaism and the Canaanite cults. This is the view of Dillmann, Ewald, and Kittel.
(6) Abraham and Sarah are free inventions of unconscious popular poetry, untrammeled by considerations of genealogical data or tribal or religious motives. Wellhausen is the main exponent of this view ("Prolegomena zur Gesch. Israels," pp. 337 et Seq.).
(7) The mythological theory makes Sarai identical with Ishtar. She and Abraham are said to be lunar deities, or adaptations of the Babylonian Adonis-Tammuz (Abraham) and Ishtar (Sarai) myths (the descent of Ishtar). Winckler (in his "Gesch. Israel's" and other writings) and Stucken ("Astralmythen") advance this view.
The most likely of all these views is the one that makes Sarai an eponym for Israel. Her marriage with Abraham represents the union of the Israel group with some clan or clans settled around Hebron. Ed. Meyer (in Stade's, "Zeitschrift," 1886) is inclined to regard even Abraham as the name and eponym of a clan or sept, and refers to Abi-ezer (Judges vi. 34). Cheyne, of course (in Cheyne and Black, "Encyc. Bibl." s.v. "Sarah"), makes Abraham a Jerahmeelite, whose marriage with Sarah expresses the amalgamation of Israel with the descendants of Jerahmeel.
Ed. Meyer, Der Stamm Jacob, In Stade's Zeitschrift, 1886;
F. Baethgen, Beiträge zur Semitischen Religionsgeschichte;
F. Hommel, Die Altisraelitische Ueberlieferung;
B. Kittel, Gesch. der Hebräer, vol. i.;
A. Dillmann, Biblische Theologie, ed. Kittel, 1895;
I. Goldziher, Der Mythos bei den Hebräern, 1876;
W. Staerk, Studien zur Religions- und Sprachgeschichte des Alttestaments, 1889, vol. i.;
Hermann Guthe, Gesch. des Volkes Israel, 1899;
H. P. Smith, Old Testament History, 1903.
E. G. H.Her Beauty. —In Arabic Literature:
Sarah, the wife of Abraham, was, according to some accounts, the sister of Lot and the daughter of Aran, Abraham's paternal uncle. According to others, she was the daughter of the King of Ḥaran, and her mother was daughter of Kutba, King of Babylon. Sarah was the most beautiful woman of her time and possessed a perfect figure. She resembled Eve, to whom God gave two-thirds of all beauty; indeed, she was so beautiful that Abraham transported her in a chest. When, on entering Egypt, Abraham was obliged to give a tithe of all his goods, he at first refused to open the chest in which Sarah was, and when he was finally forced to do so, the official ran and told the king. Questioned by the latter regarding Sarah, Abraham replied that she was his sister, having instructed her to say the same. When, on that supposition, the king wished to marry her and reached out to take her, Sarah prayed God to wither his hand; and when the king promised not to touch her, she prayed God to restore it. Forgetful of his promise, the king reached toward her once more, and his hand was again withered. This was repeated three times. Abraham was a witness of this interview, God causing the walls of the house to become transparent for the purpose. Finally the king restored Sarah to Abraham and loaded her with presents. He insisted on her choosing for herself one of his slave girls, and she selected Hagar, for whom she had conceived a liking.
Afterward Sarah gave Hagar to Abraham; and when Ishmael was born she became so jealous that she could no longer live with Hagar. On one occasion she swore that she would not rest satisfied until her hands had been dipped in Hagar's blood, whereupon Abraham immediately pierced Hagar's ears so that the blood might be on Sarah's hands. Such was the origin of the wearing of earrings. Abraham then took Hagar and Ishmael away. In after years, when he went to visit Ishmael, Sarah was still so jealous that she exacted a promise from Abraham that he would not alight from his horse.
Sarah is not directly mentioned in the Koran; but she is referred to in sura xi. 74, where she is spoken of as standing by when Abraham receives the visit of the angels. Sarah was seventy years old when she conceived Isaac (according to Ṭabari; Baiḍawi says she was ninety or ninety-nine). She lived to the age of 130. She is said to have been the mother of Jacob and Esau also, although some say that they were sons of Abraham by another wife. As long as Sarah lived Abraham had no other wife, but after her death he married Keturah. Sarah was buried in the land of Canaan in a cave bought by Abraham, where, later, he also was interred.
Mas'udi, Prairies d'Or, Index;
Ṭabari, Annales, Index, Leyden, 1879-81;
idem, Persian version, translated by Zotenberg, Paris, 1867, Index;
Weill, Biblical Legends of the Mussulmans, New York, 1846, s.v. Abraham.
J. M. W. M.


text:
Breakpoint heterogeneity in t(10;11) translocation in AML-M4/M5 resulting in fusion of AF10 and MLL is resolved by fluorescent in situ hybridization analysis
H. B. Beverloo, M. Le Coniat, J. Wijsman, D. M. Lillington, O. Bernard, A. De Klein, E. Van Wering, J. Welborn, B. D. Young, A. Hagemeijer, Jeanna L Welborn
Ten AML-M4/M5 patients' samples containing a t(10;11) translocation, but with different cytogenetic breakpoints on chromosome 11q (11q13-23), were studied by G- and R-banding and fluorescent in situ hybridization. Southern blotting analysis, studied in five patients, revealed a rearranged MLL gene. Reverse transcription-PCR analysis carried out in six patients showed a 5' MLL-3' AF-10 fusion transcript. Fluorescent in situ hybridization studies suggested that in 8 of 10 patients, the rearrangement/fusion transcript resulted from an inversion of a part of 11q (q13q23) translocated to 10p12. In the other two patients, it is assumed that an inversion/translocation has occurred of a part of 10p to the der(11). The results suggest that the orientation of the AF-10 gene on 10p is 5' telomeric and 3' centromeric. This is the first example of opposite-oriented genes being involved in translocation to yield fusion transcripts.
Chromosome Breakpoints
Southern Blotting
Beverloo, H. B., Le Coniat, M., Wijsman, J., Lillington, D. M., Bernard, O., De Klein, A., ... Welborn, J. L. (1995). Breakpoint heterogeneity in t(10;11) translocation in AML-M4/M5 resulting in fusion of AF10 and MLL is resolved by fluorescent in situ hybridization analysis. Cancer Research, 55(19), 4220-4224.
Breakpoint heterogeneity in t(10;11) translocation in AML-M4/M5 resulting in fusion of AF10 and MLL is resolved by fluorescent in situ hybridization analysis. / Beverloo, H. B.; Le Coniat, M.; Wijsman, J.; Lillington, D. M.; Bernard, O.; De Klein, A.; Van Wering, E.; Welborn, J.; Young, B. D.; Hagemeijer, A.; Welborn, Jeanna L.
In: Cancer Research, Vol. 55, No. 19, 1995, p. 4220-4224.
Beverloo, HB, Le Coniat, M, Wijsman, J, Lillington, DM, Bernard, O, De Klein, A, Van Wering, E, Welborn, J, Young, BD, Hagemeijer, A & Welborn, JL 1995, 'Breakpoint heterogeneity in t(10;11) translocation in AML-M4/M5 resulting in fusion of AF10 and MLL is resolved by fluorescent in situ hybridization analysis', Cancer Research, vol. 55, no. 19, pp. 4220-4224.
Beverloo HB, Le Coniat M, Wijsman J, Lillington DM, Bernard O, De Klein A et al. Breakpoint heterogeneity in t(10;11) translocation in AML-M4/M5 resulting in fusion of AF10 and MLL is resolved by fluorescent in situ hybridization analysis. Cancer Research. 1995;55(19):4220-4224.
Beverloo, H. B. ; Le Coniat, M. ; Wijsman, J. ; Lillington, D. M. ; Bernard, O. ; De Klein, A. ; Van Wering, E. ; Welborn, J. ; Young, B. D. ; Hagemeijer, A. ; Welborn, Jeanna L. / Breakpoint heterogeneity in t(10;11) translocation in AML-M4/M5 resulting in fusion of AF10 and MLL is resolved by fluorescent in situ hybridization analysis. In: Cancer Research. 1995 ; Vol. 55, No. 19. pp. 4220-4224.
@article{ad9831f969d34509911fdbfec9c6e6be,
title = "Breakpoint heterogeneity in t(10;11) translocation in AML-M4/M5 resulting in fusion of AF10 and MLL is resolved by fluorescent in situ hybridization analysis",
abstract = "Ten AML-M4/M5 patients' samples containing a t(10;11) translocation, but with different cytogenetic breakpoints on chromosome 11q (11q13-23), were studied by G- and R-banding and fluorescent in situ hybridization. Southern blotting analysis, studied in five patients, revealed a rearranged MLL gene. Reverse transcription-PCR analysis carried out in six patients showed a 5' MLL-3' AF-10 fusion transcript. Fluorescent in situ hybridization studies suggested that in 8 of 10 patients, the rearrangement/fusion transcript resulted from an inversion of a part of 11q (q13q23) translocated to 10p12. In the other two patients, it is assumed that an inversion/translocation has occurred of a part of 10p to the der(11). The results suggest that the orientation of the AF-10 gene on 10p is 5' telomeric and 3' centromeric. This is the first example of opposite-oriented genes being involved in translocation to yield fusion transcripts.",
author = "Beverloo, {H. B.} and {Le Coniat}, M. and J. Wijsman and Lillington, {D. M.} and O. Bernard and {De Klein}, A. and {Van Wering}, E. and J. Welborn and Young, {B. D.} and A. Hagemeijer and Welborn, {Jeanna L}",
journal = "Journal of Cancer Research",
publisher = "American Association for Cancer Research Inc.",
T1 - Breakpoint heterogeneity in t(10;11) translocation in AML-M4/M5 resulting in fusion of AF10 and MLL is resolved by fluorescent in situ hybridization analysis
AU - Beverloo, H. B.
AU - Le Coniat, M.
AU - Wijsman, J.
AU - Lillington, D. M.
AU - Bernard, O.
AU - De Klein, A.
AU - Van Wering, E.
AU - Welborn, J.
AU - Young, B. D.
AU - Hagemeijer, A.
AU - Welborn, Jeanna L
N2 - Ten AML-M4/M5 patients' samples containing a t(10;11) translocation, but with different cytogenetic breakpoints on chromosome 11q (11q13-23), were studied by G- and R-banding and fluorescent in situ hybridization. Southern blotting analysis, studied in five patients, revealed a rearranged MLL gene. Reverse transcription-PCR analysis carried out in six patients showed a 5' MLL-3' AF-10 fusion transcript. Fluorescent in situ hybridization studies suggested that in 8 of 10 patients, the rearrangement/fusion transcript resulted from an inversion of a part of 11q (q13q23) translocated to 10p12. In the other two patients, it is assumed that an inversion/translocation has occurred of a part of 10p to the der(11). The results suggest that the orientation of the AF-10 gene on 10p is 5' telomeric and 3' centromeric. This is the first example of opposite-oriented genes being involved in translocation to yield fusion transcripts.
AB - Ten AML-M4/M5 patients' samples containing a t(10;11) translocation, but with different cytogenetic breakpoints on chromosome 11q (11q13-23), were studied by G- and R-banding and fluorescent in situ hybridization. Southern blotting analysis, studied in five patients, revealed a rearranged MLL gene. Reverse transcription-PCR analysis carried out in six patients showed a 5' MLL-3' AF-10 fusion transcript. Fluorescent in situ hybridization studies suggested that in 8 of 10 patients, the rearrangement/fusion transcript resulted from an inversion of a part of 11q (q13q23) translocated to 10p12. In the other two patients, it is assumed that an inversion/translocation has occurred of a part of 10p to the der(11). The results suggest that the orientation of the AF-10 gene on 10p is 5' telomeric and 3' centromeric. This is the first example of opposite-oriented genes being involved in translocation to yield fusion transcripts.
JO - Journal of Cancer Research
JF - Journal of Cancer Research

redpajama_set_name: RedPajamaCommonCrawl


text:
Home / Posts tagged 'The Teardrop Explodes'
Vintage Video: Julian Cope thrills in hour-long 'MTV Saturday Night Concert' set from 1987
Video, Vintage Video
For this week's installment of Vintage Video, we present this MTV-broadcast concert by former Teardrop Explodes frontman Julian Cope, filmed at The Ritz in New York City on July 6, 1987, and featured during the network's "Saturday Night Concert" series. Watch the hour-long set right here.
New releases: 'Scared to Get Happy,' Lloyd Cole, Poltergeist, Jane's Addiction, Midge Ure
This week's new releases include the 'Scared To Get Happy: A Story of Indie-Pop 1980-1989' box set, new albums from Lloyd Cole and Echo & The Bunnymen's Will Sergeant, live albums from Jane's Addiction and Midge Ure, a new Three O'Clock compilation and Teardrop Explodes, Devo and Primitives reissues.
Wild Swans reissues: Occultation Recordings seeks fan input for upcoming vinyl editions
Reissues, Vinyl
Occultation Recordings is planning deluxe vinyl reissues of The Wild Swans' third album, 2011's The Coldest Winter For A Hundred Years, and a 2003 compilation of '80s radio sessions, demos and rarities called Incandescent — but first the label is taking the unusual step of asking fans what they'd like to see included.
Free MP3: The Wild Swans, 'In Secret' — ex-Teardrop Explodes, Echo & The Bunnymen
Album News, Digital Music, Tracklist
Next week, Liverpool's The Wild Swans — the brainchild of former Teardrop Explodes keyboardist Paul Simpson — will release their first album in 21 years and only their third overall, a 13-track collection called 'The Coldest Winter For a Hundred Years' that features veterans of Echo & The Bunnymen, Spiritualized and The Brian Jonestown Massacre.
New releases: INXS, The Church, Steve Wynn, New Model Army, The Teardrop Explodes
This week's new releases include INXS's disc of re-recorded hits with all-star vocalists ('Original Sin'), two reissues from The Church ('Seance,' 'Heyday'), a new studio album from ex-Dream Syndicate frontman Steve Wynn ('Northern Aggression'), a New Model Army box set ('Anthology') and the domestic reissue of The Teardrop Explodes' 'Kilimanjaro.'
Playlist: Sirius XM's 'Dark Wave,' 10/17/10
Notable spins on tonight's installment of 'Dark Wave' include not one but two cuts off The Teardrop Explodes just-reissued 1980 debut 'Kilimanjaro,' a track from Bauhaus' 2008 reunion album 'Go Away White' and a lesser-played Yazoo album cut.
Playlist: Sirius XM's 'Dark Wave,' 8/8/10
This week's 'Dark Wave' on Sirius XM's 1st Wave features many of the usual suspects — although not the oft-repeated Mission U.K. — plus some choice cuts from the likes of the Cocteau Twins ('In the Gold Dust Rush'), The Teardrop Explodes ('When I Dream') and Bigod 20 ('Carpe Diem').
New CDs: R.E.M., Concrete Blonde, Teardrop Explodes reissues, plus new Crowded House
This week's new releases include expanded reissues from R.E.M. ('Fables of the Reconstruction'), Concrete Blonde ('Bloodletting'), The Teardrop Explodes ('Kilimanjaro') and That Petrol Emotion ('Babble'), plus a new compilation from My Life With the Thrill Kill Kult ('Sinister Whisperz') and the belated U.S. release of Crowded House's new album 'Intriguer.'
The Teardrop Explodes' 'Kilimanjaro,' Julian Cope's 'Floored Genius 2' set for reissue
Reissues, Tracklist
The debut album from Julian Cope's neo-psychedelic band The Teardrop Explodes — 1980's 'Kilimanjaro' — is due to receive an expansive 3CD reissue next month, along with Cope's 1993 compilation of post-Teardrop recordings entitled 'Floored Genius 2: Best of the BBC Sessions 1983-1991.'
New releases: Frankie Goes to Hollywood, Buggles, Madness reissues, plus live Plimsouls
This week's new releases include reissues from Frankie Goes to Hollywood ('Welcome to the Pleasuredome'), Buggles ('Adventures in Modern Recording'), Madness ('Absolutely,' '7'), Julian Cope ('Peggy Suicide') and A Certain Ratio ('Force'), plus a new Plimsouls live album from 1981.
New releases: Kraftwerk's 'Catalogue' box set, reissues from Julian Cope, Avengers
Tweet Record Rack: A round-up of the week's new albums, reissues and/or box sets. ARTIST: Kraftwerk RELEASE: The Catalogue BACKSTORY: The eight albums featured in […]


We were invited to attend an apple team away day to a succulent terrarium workshop. We took everything needed, including 180 little succulents to a fantastic venue, The Victoria Loft at Lumiere London.
What terrarium did they make?
Looking for a company wide or team terrarium workshop? Let us know and we can put together a package for you.
London plant installation - Science Beaker Terrariums.


"Are Americans finally ready to stop treating business tycoons like superheroes?"
"I hope that it will contribute to the end of our naive glorification of tycoons."
why we tend to celebrate our business leaders to such an excessive degree."
entourage) to the summit of power."


Charming 3 bedroom, 2 bathroom beach cottage in the South Beach area of Sea Pines Plantation. Located next to community pool and tennis courts in the Beachside Homes complex. This lovely home has a fully equipped kitchen including a KitchenAid mixer and Dualit toaster. The screened in front porch with Lloyd Flanders patio furniture makes for a perfect place to relax and unwind. This home has 3 bedrooms. One king suite, a queen bedroom, and a bedroom with 2 twins. This home is perfect for a small family. This incredible location is only a three-minute walk to the beach and the quaint South Beach Marina Village featuring the famous Salty Dog Cafe. Just a ten-minute drive to Harbour Town, the jewel of Hilton Head. Enjoy everything Sea Pines Plantation has to offer at this South Beach home.
? The Vacation Company App will contain all of your check-in information (keyless door code, Wi-Fi Codes, and other information pertinent to your stay).
The only problem, which was at no fault to the owner or rental co., was the new AC unit. It was a whole day event and the way the hosue was set up we could not use a bathroom and bedroom all day. It was tough for us because we had little kids who napped. The workers did their best, but it still was a bummer. At least the AC was fixed for the last 2 days.
The Vacation Company Show Phone No.


text:
Q: How can I parse JSON into a binary Avro file using the Python Avro api? I am able to use the avro-tools-1.7.7.jar to take json data and avro schema and output a binary Avro file as shown here https://github.com/miguno/avro-cli-examples#json-to-avro. However, I want to be able to do this programmatically using the Avro python api: https://avro.apache.org/docs/1.7.7/gettingstartedpython.html.
In their example they show how you can write a record at a time into a binary avro file.
    import avro.schema
    from avro.datafile import DataFileReader, DataFileWriter
    from avro.io import DatumReader, DatumWriter

    schema = avro.schema.parse(open("user.avsc").read())

    writer = DataFileWriter(open("users.avro", "w"), DatumWriter(), schema)
    writer.append({"name": "Alyssa", "favorite_number": 256})
    writer.append({"name": "Ben", "favorite_number": 7, "favorite_color": "red"})
    writer.close()

My use case is writing all of the records at once like the avro-tools jar does from a json file, just in python code. I do not want to shell out and execute the jar. This will be deployed to Google App Engine if that matters.

A: This can be accomplished with fastavro. For example, given the schema in the link:
twitter.avsc
{
  "type" : "record",
  "name" : "twitter_schema",
  "namespace" : "com.miguno.avro",
  "fields" : [ {
    "name" : "username",
    "type" : "string",
    "doc" : "Name of the user account on Twitter.com"
  }, {
    "name" : "tweet",
    "type" : "string",
    "doc" : "The content of the user's Twitter message"
  }, {
    "name" : "timestamp",
    "type" : "long",
    "doc" : "Unix epoch time in seconds"
  } ],
  "doc:" : "A basic schema for storing Twitter messages"
}

And the json file:
twitter.json
{"username":"miguno","tweet":"Rock: Nerf paper, scissors is fine.","timestamp": 1366150681 }
{"username":"BlizzardCS","tweet":"Works as intended.  Terran is IMBA.","timestamp": 1366154481 }

You can use something like the following script to write out an avro file:
import json
from fastavro import json_reader, parse_schema, writer

with open("twitter.avsc") as fp:
    schema = parse_schema(json.load(fp))

with open("twitter.avro", "wb") as avro_file:
    with open("twitter.json") as fp:
        writer(avro_file, schema, json_reader(fp, schema))

redpajama_set_name: RedPajamaStackExchange


Unistrut Launches Strongest Strut Bracket in the Market!
The Unistrut P2580 is the highest capacity cantilevered strut bracket in the market! Designed to hold heavier loads, increase the span between supports, and allow attachment on top and bottom. Order today and see the SIGNIFICANT difference in material and labor cost savings! Click here to learn more!
Kaf-Tech now offers MC Luminary Cable which includes lighting and low voltage circuits in one steel or aluminum armored cable. For use with LED and Fluorescent dimming as well as SMART Buildings. Click HERE to see a detailed spec sheet on this revolutionary product.
Remke PowR-Teck™ MC Cable Connectors are designed to form a watertight seal around the jacketed metal cable and at the enclosure entry. Rated NEMA 4 and IP 65, these connectors are in-stock in 1/2" to 4" hub sizes in aluminum, nickel-plated aluminum and stainless steel.
The breathable liner for the 3M™ Comfort Grip Cut-Resistant Glove CGM-CR is designed to withstand cuts, punctures and tears without loss of dexterity. The nitrile palm coating on these medium-duty glove provides firm grip even for wet or slippery jobs. The Difference is in the Grip - download this brochure for complete details.


text:
Lonnika Thompson
SIX BITS: SEC titles, softball sweep, gymnastics
February 28, 2010 | By Adam Silverstein
1 » No. 3 Florida Gators women's track and field won the 2010 Southeastern Conference Indoor Championship Sunday, its first since the 2004 season. Scoring 110 total points, the team was led...
TWO BITS: Four more SEC titles, women fall to UK
Opening BIT » Congratulations to forward/center Al Horford of the Atlanta Hawks for a career-high 31 points in his 200th NBA game on Wednesday! "In the fourth quarter, I looked up at...
FOUR BITS: McCray's ring, Sunday sports wrap
February 8, 2010 | By Adam Silverstein
1 » On Sunday, New Orleans Saints defensive end Bobby McCray became the 13th former Florida Gators football player to win a Super Bowl as his team defeated the Indianapolis Colts 31-17...
SIX BITS: Dungy on Tebow, Jaguars, weekend
1 » Former Indianapolis Colts and Tampa Bay Buccaneers head coach and current NFL analyst for NBC Tony Dungy continues to stand behind former Florida Gators quarterback Tim Tebow and believes he...
Parsons' buzzer-beater drops N.C. State in OT
January 3, 2010 | By Adam Silverstein
Down two with 2.6 seconds left on the clock in overtime and N.C. State Wolfpack guard Farnold Degand on the line ready to shoot his second free throw, the Florida Gators' hopes...


This composition for Easy Piano includes 4 page(s). It is performed by Norman Gimbel. The style of the score is 'Pop'. Catalog SKU number of the notation is 31712. This score was originally published in the key of C. Authors/composers of this song: English Words by NORMAN GIMBEL Portuguese Words by RONALDO BOSCOLI Music by ROBERTO MENESCAL. This score was first released on Wednesday 9th February, 2005 and was last updated on Friday 24th March, 2017. The arrangement code for the composition is EPF. Minimum required purchase quantity for these notes is 1. Please check if transposition is possible before your complete your purchase.
* Where transpose of 'Telephone Song' available (not all our notes can be transposed) & prior to print.


text:
Facilities Management Office
Strengthening mainland ties
In an effort to strengthen its academic ties with universities and research institutes, City University of Hong Kong President, Professor H K Chang, is leading a CityU delegation to the mainland. The visit runs from 23 to 28 April.
Buddhist organization's generous donation
The College's Division of Language Studies (LS) received a donation of $100,000 from Soka Gakkai International of Hong Kong Ltd at a presentation ceremony held at CityU on 18 April.
SCM Professor produces award-winning documentary
A television documentary produced by a professor at the School of Creative Media (SCM) has won a prestigious Peabody Award, the most renowned prize in broadcast journalism.
CityU community at Guangzhou Walkathon
When Mr Kingston Sun, our Facilities Manager, signed up for the "Walk to Guangzhou" fundraising activity organized by Sowers Action in January this year, he never expected to meet so many colleagues, ex-colleagues and CityU students at the event.
Coaches of CityU Sports Teams
Thanks to our coaches who helped the CityU Sports Teams take the championships at this year's inter-collegiate competitions.


Look, we know that it's the time of year when everyone and their sister has a list of the best horror movies of all time. This time out, we at Rotten Tomatoes decided to take a slightly different tack. Using our weighted formula, we compiled a list of the best-reviewed fright fests from each year since 1920 — the year The Cabinet of Dr. Caligari, which created the template for horror cinema, was released. This wasn't an easy assignment — there were several years, like 1932 and 1960, that boasted a slate of classic films (and a few others, like 1937 and 1938, in which we had trouble finding any solid contenders). What was the best horror flick the year you were born? Check out our list — if you dare.
Critics Consensus: Arguably the first true horror film, The Cabinet of Dr. Caligari set a brilliantly high bar for the genre -- and remains terrifying nearly a century after it first stalked the screen.
Critics Consensus: One of the silent era's most influential masterpieces, Nosferatu's eerie, gothic feel -- and a chilling performance from Max Schreck as the vampire -- set the template for the horror films that followed.
Critics Consensus: A heart-rending take on the classic book, with a legendary performance by Lon Chaney.
Directed By: Wallace Worsley, Wallace Worsley Sr.


Notoriously pro-Israel media conglomerate CanWest Global Communication filed a lawsuit against at least 3 Vancouver activists who allegedly produced a pro-Palestine parody of a Vancouver Sun issue last year.
CanWest owns the Vancouver Sun as well as dozens of other media outlets, including Global TV, the National Post, canada.com, and almost all dailies and weeklies in the Vancouver area.
"In June 2007, the Palestine Media Collective produced and distributed 12,000 copies of a newspaper parody of the Vancouver Sun that satirized Canwest's anti-Palestinian bias... Canwest has launched an unprecedented civil lawsuit against local activists... for "conspiring" to produce and distribute a four-page parody of the Vancouver Sun's satirising Canwest's biased coverage of Israel's illegal occupation of Palestinian territories."
Tuque Souq book alert: "L'art arabe"
Canada Votes October 14, 2008!


Who doesn't love a good trip to the beach? There's something just so nice about the cool waves of the water and the warm sand beneath your toes.
Sometimes, though, that sand gets a little too hot if it's really hot outside. You know what we're talking about: when you step on it barefoot and it scorches the soles of your feet.
Sand can get really, really hot—it's no joke. The Palm Beach Post in Palm Beach County, Florida estimates that sand temperatures at Ocean Reef Park in Riviera Beach can get to be as high as 120 degrees Fahrenheit, and other beaches are likely similar. And that can really do damage to your feet.
"It can be quite painful to your feet," said Roger Amidon, the general manager of the Palm Beach Marriott Singer Island Beach Resort & Spa, which uses a soaker hose to keep their sand cool between the hotel and its beachfront chairs.
It's especially worse for children—they can really feel the hot sand beneath their little piggies. "Little kids will start walking and then they'll just stop and start crying," said Don May, with Palm Beach County Ocean Rescue.
So how do you prevent your feet from burning off when you're walking through the sand? Well, one way is pretty simple: "Most people just sprint for their lives to the water," says May.
If you came to the beach to go swimming, this method works well, of course. But if you're trying to take a walk on the beach, or just trying to get from your towel to the snack bar without feeling like your feet are on fire, what can you do?
Some health officials suggest trying the "run, stop, bury" technique. This is just what it sounds like: you run as fast as you can to where you want to be on the beach, and if you feel your feet getting too hot, stop what you're doing, and then bury your feet as far into the cooler sand below the surface as you can get. This is the fastest way to provide relief when you're still on the sand.
Of course, another seemingly obvious but simple tip is to just keep your sandals on while you walk on the beach to protect your feet.
And no, contrary to popular belief, one type of sand isn't always better than another. All sand rises in temperature under the sun. "If you have 95-degree heat and you're walking barefoot it can be very uncomfortable on your feet whether it's white sand or dark sand," said Jeff Williams, a senior coastal emeritus scientist with the U.S. Geologic Survey in Massachusetts.
If your feet do get burned from the sand, try soaking your feet in cool water, applying a soothing cream, hydrate yourself with water, and give your feet some time to recover before stepping on the sand again.
For some more great tips on preventing sand burn on your feet all summer long, check out this video below.
Have you ever burned you feet from stepping in hot sand before? What do you do to try to keep your feet from getting burned in the sand?


text:
<!DOCTYPE html>

<meta content="text/html; charset=utf-8" http-equiv="Content-Type">

<title>class Rack::File - 'Rack Documentation'</title>

<link type="text/css" media="screen" href="../rdoc.css" rel="stylesheet">

    Home
    Classes
    Methods

  <form action="#" method="get" accept-charset="utf-8">

      <input type="text" name="search" placeholder="Search" id="search-field"
             title="Type to search, Up and Down to navigate, Enter to load">

  </form>

Defined In

lib/rack/file.rb

Parent

Object

Methods

::new

#_call

#call

#each

#serving

Pages

KNOWN-ISSUES

README

SPEC

Class and Module Index

Rack

Rack::Auth

Rack::Auth::AbstractHandler

Rack::Auth::AbstractRequest

Rack::Auth::Basic

Rack::Auth::Basic::Request

Rack::Auth::Digest

Rack::Auth::Digest::MD5

Rack::Auth::Digest::Nonce

Rack::Auth::Digest::Params

Rack::Auth::Digest::Request

Rack::BodyProxy

Rack::Builder

Rack::Cascade

Rack::Chunked

Rack::Chunked::Body

Rack::CommonLogger

Rack::ConditionalGet

Rack::Config

Rack::ContentLength

Rack::ContentType

Rack::Deflater

Rack::Deflater::DeflateStream

Rack::Deflater::GzipStream

Rack::Directory

Rack::ETag

Rack::File

Rack::ForwardRequest

Rack::Handler

Rack::Handler::CGI

Rack::Handler::EventedMongrel

Rack::Handler::FastCGI

Rack::Handler::LSWS

Rack::Handler::Mongrel

Rack::Handler::SCGI

Rack::Handler::SwiftipliedMongrel

Rack::Handler::Thin

Rack::Handler::WEBrick

Rack::Head

Rack::Lint

Rack::Lobster

Rack::Lock

Rack::Logger

Rack::MethodOverride

Rack::Mime

Rack::MockRequest

Rack::MockRequest::FatalWarner

Rack::MockRequest::FatalWarning

Rack::MockResponse

Rack::Multipart

Rack::Multipart::Generator

Rack::Multipart::Parser

Rack::Multipart::UploadedFile

Rack::NullLogger

Rack::Recursive

Rack::Reloader

Rack::Reloader::Stat

Rack::Request

Rack::Response

Rack::Response::Helpers

Rack::RewindableInput

Rack::RewindableInput::Tempfile

Rack::Runtime

Rack::Sendfile

Rack::Server

Rack::Server::Options

Rack::Session

Rack::Session::Abstract

Rack::Session::Abstract::ID

Rack::Session::Abstract::SessionHash

Rack::Session::Cookie

Rack::Session::Cookie::Base64

Rack::Session::Cookie::Base64::Marshal

Rack::Session::Cookie::Identity

Rack::Session::Cookie::Reverse

Rack::Session::Memcache

Rack::Session::Pool

Rack::ShowExceptions

Rack::ShowStatus

Rack::Static

Rack::URLMap

Rack::Utils

Rack::Utils::Context

Rack::Utils::HeaderHash

Rack::Utils::Multipart

FCGI

FCGI::Stream

class Rack::File

Rack::File serves files below the root
directory given, according to the path info of the Rack request. e.g. when ::new("/etc") is used, you can access
'passwd' file as localhost:9292/passwd

Handlers can detect if bodies are a Rack::File, and
use mechanisms like sendfile on the path.

Constants

F

SEPS

Attributes

          cache_control[RW]

          path[RW]

          root[RW]

          to_path[RW]

Public Class Methods

          new(root, cache_control = nil)
          click to toggle source

# File lib/rack/file.rb, line 23
def initialize(root, cache_control = nil)
  @root = root
  @cache_control = cache_control
end

Public Instance Methods

          _call(env)
          click to toggle source

# File lib/rack/file.rb, line 34
def _call(env)
  @path_info = Utils.unescape(env["PATH_INFO"])
  parts = @path_info.split SEPS

  return fail(403, "Forbidden")  if parts.include? ".."

  @path = F.join(@root, *parts)

  available = begin
    F.file?(@path) && F.readable?(@path)
  rescue SystemCallError
    false
  end

  if available
    serving(env)
  else
    fail(404, "File not found: #{@path_info}")
  end
end

          call(env)
          click to toggle source

# File lib/rack/file.rb, line 28
def call(env)
  dup._call(env)
end

          each() { |part| ... }
          click to toggle source

# File lib/rack/file.rb, line 95
def each
  F.open(@path, "rb") do |file|
    file.seek(@range.begin)
    remaining_len = @range.end-@range.begin+1
    while remaining_len > 0
      part = file.read([8192, remaining_len].min)
      break unless part
      remaining_len -= part.length

      yield part
    end
  end
end

          serving(env)
          click to toggle source

# File lib/rack/file.rb, line 55
def serving(env)
  # NOTE:
  #   We check via File::size? whether this file provides size info
  #   via stat (e.g. /proc files often don't), otherwise we have to
  #   figure it out by reading the whole file into memory.
  size = F.size?(@path) || Utils.bytesize(F.read(@path))

  response = [
    200,
    {
      "Last-Modified"  => F.mtime(@path).httpdate,
      "Content-Type"   => Mime.mime_type(F.extname(@path), 'text/plain')
    },
    self
  ]
  response[1].merge! 'Cache-Control' => @cache_control if @cache_control

  ranges = Rack::Utils.byte_ranges(env, size)
  if ranges.nil? || ranges.length > 1
    # No ranges, or multiple ranges (which we don't support):
    # TODO: Support multiple byte-ranges
    response[0] = 200
    @range = 0..size-1
  elsif ranges.empty?
    # Unsatisfiable. Return error, and file size:
    response = fail(416, "Byte range unsatisfiable")
    response[1]["Content-Range"] = "bytes */#{size}"
    return response
  else
    # Partial content:
    @range = ranges[0]
    response[0] = 206
    response[1]["Content-Range"]  = "bytes #{@range.begin}-#{@range.end}/#{size}"
    size = @range.end - @range.begin + 1
  end

  response[1]["Content-Length"] = size.to_s
  response
end

[Validate]

Generated by RDoc 3.12.

Generated with the Darkfish Rdoc Generator 3.

redpajama_set_name: RedPajamaGithub


Massive gender imbalance leaves men unable to find wives.
The Chinese government says its so-called "one-child policy" has succeeded in reining in its population.
Al Jazeera's Melissa Chan reports from Hainan in the country's south, women, it appears, are nowhere to be found.


text:
Daughter flies 'into rage,' kills mom and leaves her body in the garage
by KC Wildmoon
A Florida woman allegedly told sheriff's deputies she went "into a rage" over something her mother said and attacked her, fighting for several minutes until the 81-year-old mother was dead.
Deputies found Carmelina Kohler's body late Monday covered with boxes and a blanket in her Vero Beach garage, where Crystal Kohler, 38, had left her, WPTV reported.
Detectives said Carmelina Kohler had been stabbed in the neck and abdomen.
It's True Justice Month on Fox Nation, and "Crimes Stories with Nancy Grace" is available now! Sign up today and get your first month for only 99 cents!
The sordid tale began Monday afternoon when Carmelina's husband came home and found Crystal alone at the house, even though he knew the mother and daughter had planned to go to a nail appointment at 2 p.m.
"Crystal told [him that her mother] had sent her home to change her clothing, because she looked like a bum," the arrest report said. "Crystal changed her clothing and left the residence."
She drove off in Carmelina's 2018 Chrysler Pacifica. At about 8 p.m. Monday evening, the husband received a call from someone who found Carmelina's cellphone some distance away. He called police, reporting his wife missing and the van stolen.
Later in the evening, detectives spoke with Crystal Kohler's ex-boyfriend, Matt Wilhelm, who told them she'd arrived unannounced at his home and was distraught.
"He asked her what was wrong and she told him the less he knew the better," the report said.
The report said the two went to a Walmart in Vero Beach, and Wilhelm gave her $120, according to Treasure Coast Palm. She told him she was taking a bus to Tennessee. But detectives searched his cellphone, finding a text message from her saying the needed a ride to "u know where" Tuesday morning but first she needed to "ditch" the van.
And that's when investigators learned she was hiding on a boat Wilhelm owned at Fort Pierce Marina. Crystal Kohler was arrested and charged with grand theft auto and driving with a suspended license after the van was found in a nearby garage.
But the story wasn't over. During the initial interview Monday night, Kohler became upset and requested a lawyer, ending the interview. The following day, she again agreed to talk with detectives, and this time said her mother was dead in the garage.
"She did not elaborate on the details of how her mother came to be deceased, but she did admit that she was responsible for her death," the report said.
She was charged with first degree murder and is being held without bond.
"An 81-year-old person does not deserve to have their life ended like this," Indian River County Sheriff Deryl Loar said.
For the latest true crime and justice news, subscribe to the 'Crime Stories with Nancy Grace' podcast. Listen to a related episode:
Join Nancy Grace for her new online video series designed to help you protect what you love most – your children.
[Featured image: Crystal Kohler/Indian River County Sheriff's Office]


Thanks for submitting your review of Quantbuilder Algorithmic Trading. We'll email you as soon as it's published, (typically within 48 hours). We really value your contributions, and so does our community of business professionals. They count on honest reviews like yours.
Thanks for submitting your review of Quantbuilder Algorithmic Trading.
Thanks for submitting your review of QuantHouse. We'll email you as soon as it's published, (typically within 48 hours). We really value your contributions, and so does our community of business professionals. They count on honest reviews like yours.
Thanks for submitting your review of QuantHouse.
Thanks for submitting your review of Quantifi. We'll email you as soon as it's published, (typically within 48 hours). We really value your contributions, and so does our community of business professionals. They count on honest reviews like yours.
Thanks for submitting your review of Quantifi.
Rate and Review Quartet Financial Systems Inc.
Thanks for submitting your review of Quartet Financial Systems Inc.. We'll email you as soon as it's published, (typically within 48 hours). We really value your contributions, and so does our community of business professionals. They count on honest reviews like yours.
Thanks for submitting your review of Quartet Financial Systems Inc..
Rate and Review Quinnox Inc.
Thanks for submitting your review of Quinnox Inc.. We'll email you as soon as it's published, (typically within 48 hours). We really value your contributions, and so does our community of business professionals. They count on honest reviews like yours.
Thanks for submitting your review of Quinnox Inc..
Thanks for submitting your review of Quod Financial. We'll email you as soon as it's published, (typically within 48 hours). We really value your contributions, and so does our community of business professionals. They count on honest reviews like yours.
Thanks for submitting your review of Quod Financial.
Thanks for submitting your review of QUODD Financial Information Services. We'll email you as soon as it's published, (typically within 48 hours). We really value your contributions, and so does our community of business professionals. They count on honest reviews like yours.
Thanks for submitting your review of QUODD Financial Information Services.
Rate and Review Quovo, Inc.
Thanks for submitting your review of Quovo, Inc.. We'll email you as soon as it's published, (typically within 48 hours). We really value your contributions, and so does our community of business professionals. They count on honest reviews like yours.
Thanks for submitting your review of Quovo, Inc..


As a former national level athlete I love seeing what other strength coaches and athletes do in their training.
With this in mind, I recently reached out to Matrixx Ferreira, H. BScKin, CSCS, CSEP-CEP, of Iron Athletics Canada, for his favorite workout routine.
Ferreira has a lot of experience training athletes, having been the Head Strength and Conditioning Coach for Niagara College men's basketball. He specializes in working with combat sport athletes, while also providing general personal training services.
He sent over the following workout routine that was built for a group of competitive rowers that he works with.
Here is Coach Ferreira to break down how the workout goes down.
This workout is geared for my rowing boys (seniors in high school), taking place during the specific prep phase of our annual training plan.
The focus is developing explosive movement while still building strength in rowing pattern lifts. We want to ensure we make use of the short time we have so we actively pair certain exercises into one movement.
This workout can be done at junior to senior ages so long as the athletes have a firm grasp of basic lifting fundamentals. The focus is quality over quantity. Start light and do it right before you progress to see success.
We always start with a dynamic warmup and progress to light mobility work. Rowers tend to have tight hips and lower backs so it is important to highlight a whole body approach. Even though they may never use a shuffle, we want them to move like athletes and compete as rowers. This will ensure injuries are kept to a minimum and recovery is promoted.
Always remember we are not training weightlifters, we are training athletes.
Keep the lifts purposeful and within their limitations.
The power exercises (2A and 2B) are rowing specific. We want to emphasize fast bar speed and a fast transition. By performing a high pull before executing a clean, the athlete is forced to transition at the highest speed possible. Rest time should be a minimum of 2-3 minutes. Have them work in groups of three or four to ensure rest time.
Strength exercises (3A and 3B) activate hinge muscles necessary to succeed on the water. We add a Bent Row to their RDL to get as much muscle activation in their posterior chain with the time we have allocated. Rest time should be 1-2minutes. As mentioned above, group work is very effective to ensure this.
A big thank you to Coach Ferreira for taking the time to submit this workout routine. You can check out the full list of services that he provides via his company Iron Athletics Canada online here. Stay up to date with them on Twitter and on Instagram.


Drought is inevitable in California, but the last three years have been exceptionally dry. The press has concentrated on the West, but the California drought might serve as a wakeup call to all Americans about our nation's dwindling water supply. Lack of yearly rainfall is only one factor in our current drought conditions; much of the water we use every day is actually unseen, stored underground in thousands of aquifers. We pump millions of gallons from these hidden stores each day, causing wells to go dry and land to sink, and threatening wild areas. The United States Geological Association compares aquifers to a bank account: Rainfall is our income, and the level of ground water in an aquifer is the account balance. America, then, is on a seemingly endless spending spree, systematically overdrawing our water supply each year. Click here to learn more.
When we look to the American West the scarcity of water is plainly visible. But what can we do? How can we all use our water more responsibly now to ensure a more secure future? Shrink or eliminate our lawns? Sure. Use drip irrigation? Yes. Recycle water? Of course. Plant more vegetables and fruits? Believe it or not, yes.
According to TreeHugger, a media outlet for sustainability news, the average commercial grower uses 15 gallons of water to raise one pound of lettuce, 22 gallons per pound of tomatoes, and 30 gallons for each pound of potatoes. John Jeavons, author of the best-selling How to Grow More Vegetables, has determined that using his Biointensive system, the average home gardener can use as little as 12% of the water a commercial grower uses for each pound of vegetables produced.
Many homeowners, especially in arid climates, use more than half their household's water on landscaping, so the biggest water savings can be made here. Here are some ways to cut down on water use in the garden.
A 3-inch layer of compost turned into your soil at a 6-inch depth (about a shovel blade depth) is estimated to increase the water holding capacity of that soil by 250%. Soils composted in this manner can provide plants with water for up to a week between watering. The Rodale Institute has a simple equation: 1 pound of carbon (a. k. a. compost) equals 40 pounds of water retention.
Use garden compost, pine needles, aged sawdust, fall leaves, and/or straw to mulch. For annual flowers and vegetables make sure that your compost is well aged or the soil microbes will rob the soil of needed nitrogen. The looser the material the more you need to watch for slugs and snails that can hide in the mulch. Keep the mulch 6" away from the crown of annuals, shrubs, and tree trunks to prevent diseases.
Surface roots dry out faster than those at least 6" deep. Consider buying an irrigation timer, and set it to water for shorter periods of time and water a second time a few hours later, this way the water will penetrate more deeply. Most irrigation timers can be set to do this. A great tool to make sure your plants are watered properly is a soil probe. Push the probe into the soil as far as you can, 6" to a foot deep or more, remove it and look at the sample and see if it contains damp or dry soil. And use the internet to help you identify hydrophobic soil. When soil gets very dry it actually sheds water just like a dry sponge and you need to apply water slowly and let it be absorbed or most of your water will drain away.
Avoid cheap irrigation "kits." They can be unreliable. It is hard to find replacement parts for repairs and some cheap plastic tubing can expand in hot weather forcing the emitters to pop off.
Instead, use professional grade in-line emitters that drip water from holes in the line rather than a solid tubing system with installed emitters.
Choose "shrubblers" and micro-sprayers for annuals in containers; look for flow control so you can adjust the water pattern for changing individual plants.
Install a good filter and change it every few months.
Cover the tubing with mulch, not only because it looks better, but because it protects the plastic from ultraviolet light so it lasts longer.
Run the system every few weeks to make sure that there are no leaks or clogs. You can have an irrigation specialist install your system or, for DIY, go to a plumbing supply store for help and parts, or seek out information online.
Deep root-watering large trees is much more efficient than most irrigation techniques as it distributes water a foot or more below the surface. Done properly a few times a summer, it eliminates surface run off and reduces erosion and evaporation. There are injection tools that attach to the hose and are inserted into the soil in 6 or 8 areas around the drip line of the shrub or tree and are run for a few hours at a time. Or use an old plastic garbage can with a few holes in the bottom. Move it to the drip line and fill it with water and let it slowly leak into the soil; when it's empty, move it to another quadrant.
Gray water is defined as relatively clean waste water from showers, baths, sinks, and washing machines. I keep a few plastic gallon buckets near my kitchen and bathroom sinks and put the buckets under the faucet when I'm bringing hot water to the sink or shower, and I use them when I rinse vegetables, my hands, etc.
Gray water is suitable for use in the garden because soil microbes tie up most disease organisms and toxins. When using gray water, avoid laundry soaps that contain sodium, salt compounds, and boron which can damage plants. Look for biodegradable products if you plan on using greywater. For much more information on gray water and soap brands consult Greywater Action.
Rain barrels are a natural for rainy climates, but how about in arid climates? I have found my two 75 gallon barrels quite useful. Certainly I collect rain water during our rainy season, but I also use them all year long to store gray water from the house to water my plants. For a diagram and guidelines on how to best use rainwater see the city of Berkeley's website for information.
With California's drought predicted to persist, many farmers must leave their land fallow in the state that produces more than half of the nation's produce. We can expect the price of produce to increase dramatically in the next year. For those who choose to grow their own produce – and even those who don't – water conservation may soon be more important than ever.
Garden and food writer, photographer and landscape designer with a passion for beautiful vegetables and ecologically sensitive gardening, Rosalind Creasy is the author of multiple books, including The Complete Book of Edible Landscaping. Throughout her more than 30-year career in horticulture, she has continued to share her knowledge of gardening and cooking by writing, lecturing nationwide, and appearing on television and radio shows. Her photographs appear frequently in numerous magazines, calendars (including Seed Saver Exchange's annual calendar) and books.


RevDL.me – Download CATS: Crash Arena Turbo Stars v2.9 Mod Apk latest version for mobile free download Download Game Android premium unlocked files, android apk, android apk download, apk app download, apk apps, apk games, apps apk, best apk games, free android apk, free apk, game apk, game hacker apk, free crack games, mod apk games, Android Mod Apk, download game mod apk offline, mod apk revdl. CATS: Crash Arena Turbo Stars v2.9 Mod Apk the latest version game for Android #ANDROIDGAMES and Blackberry 10 #BB10 OS with direct link apk only for free download and no pop ads.
CATS: Crash Arena Turbo Stars v2.9 Mod Apk Build your own battle bot and unleash its power in this stylish PvP game!


text:
Moffitt team members helps to retrieve biobank samples from Puerto Rico after Hurricane Maria hit the island.
Photo By Will Vragovic | Tampa Bay Times
Six Months after Hurricane Maria, Moffitt is Oasis in the Storm
By Contributing Writer - March 19, 2018
March 20, 2018 holds special meaning for many Puerto Ricans like Esteban Ocasio and his 80-year old mother Angelina Carle. The date marks six months since Hurricane Maria devastated their island home. It's also the day this pair will make their first trip back since an October 2017 humanitarian flight brought them to Tampa to continue Carle's treatment at Moffitt Cancer Center.
That flight out was "God's miracle," says Ocasio, though just making it to the plane was never assured. The two live in San Juan, where Carle underwent a partial mastectomy for metastatic breast cancer in May. Though their homes in the city were still standing after the storms, Ocasio says the devastation was beyond words. "No power. Everything was closed, so there was very little food. Only a few places were selling water, and rationing it to four small bottles a day for hundreds of people waiting in lines. With my mother still recovering from surgery, hygiene was very difficult." Getting the chemotherapy she needed in a timely fashion was out of the question.
Relatives stateside had a family member treated successfully at Moffitt and made phone calls to get Carle on the humanitarian flight. But getting to the chartered plane would take an hours-long cab ride across the debris-strewn island to the city of Ponce. That's where Moffitt was gathering cancer evacuees along with priceless frozen cancer tissue samples bio-banked through its partners at Ponce Health Sciences University (PHSU) for the return trip to Tampa.
Safely settled at Moffitt, Carle has been through two rounds of chemo with several hospitalizations along the way. She is now well enough to travel. And her caregiver son is eternally grateful. "Leaving behind all the horrible conditions at home for the chance to be treated at Moffitt has been one of the most extraordinary experiences of our lives. It's like we were in a desert, and Moffitt was our oasis."
They were not alone in seeking Moffitt's care after hurricanes Irma and Maria. Though Moffitt typically averages 40 patients per month from the island, that figure spiked over the past six months to more than 100 patients in October 2017 alone.
Moffitt delivered care directly to the island as well. From Maria's landfall through the rest of 2017, Moffitt physicians and advanced practice professionals volunteered each weekend, flying often at their own expense to provide care and supplies to the hardest hit areas of Puerto Rico. Moffitt's United Way campaign added an option to donate to Puerto Rico relief efforts. Donated goods were boxed and shipped. Even blood was collected through a special OneBlood/Moffitt blood drive.
And just weeks after the hurricane, Moffitt's longstanding partnership with PHSU received renewal of a nearly $9-million dollar grant from the National Institutes of Health. The funding sustains a long-term collaboration to improve cancer outcomes in the Hispanic/Latino population through basic and clinical research, the creation of a unique Hispanic/Latino biobank and programs for cancer education and outreach.
One outreach example is an April 28th program in San Juan made possible through Moffitt's Puerto Rico Advisory Council. Moffitt psychiatrist Dr. Margarita Bobonis Babilonia's "Conversations about Cancer" will offer techniques for caregivers coping with the psychological impacts of stress and cancer.
It's a topic Esteban Ocasio knows all too well. But he won't be in San Juan for the presentation. "We are coming back to Tampa," he promises.
"Mother's oncologist, Dr. Martine Extermann, is a brilliant physician. We have such faith in her and all the other doctors from Moffitt and the University of South Florida. We are seriously thinking of making Tampa our home."
Community Treatment Research Metastatic Breast Cancer Breast Cancer Support
Dallas Cowboys Owner Jerry Jones Joins Moffitt Cancer Center's National Board of Advisors
Jones joins 36 prominent individuals from across the nation on Moffitt's national Board of Advisors.
Moffitt Receives Super Bowl LV Forever 55 Micro Grant
The funds will help support HPV vaccinations at the Ybor Youth Clinic
From Volunteer to Registered Nurse
Angelica Casey has been living Moffitt's mission since age 16


text:
Polio on its way out
One strain of a vaccine preventable disease has been declared eradicated by world health experts
On World Polio day on 24 October, an independent commission of experts concluded that wild poliovirus type 3 (WPV3) has been eradicated globally.
According to the World Health Organization's newsroom, this is a "historic achievement for humanity," after the eradication of smallpox as well as wild poliovirus type 2.
"The achievement of polio eradication will be a milestone for global health. Commitment from partners and countries, coupled with innovation, means of the three wild polio serotypes, only type one remains," said Dr Tedros Adhanom Ghebreyesus, Director-General of the World Health Organization and Chair of the Global Polio Eradication Initiative (GPEI) Polio Oversight Board.
"We remain fully committed to ensuring that all necessary resources are made available to eradicate all poliovirus strains.
"We urge all our other stakeholders and partners to also stay the course until final success is achieved."
WPV2 was declared eradicated in 2015.
Meanwhile WPV3's last case was documented in Nigeria, in 2012, and since then global health surveillance systems have worked to confirm that this particular strain is no longer.
The WHO celebrated the eradication of the disease in an event at its Geneva, Switzerland headquarters.
"This this is a significant achievement that should reinvigorate the eradication process and provides motivation for the final step – the eradication of wild poliovirus type 1," said Professor David Salisbury, chair of the independent Global Commission for the Certification of Poliomyelitis Eradication.
"This virus remains in circulation in just two countries: Afghanistan and Pakistan. We cannot stop our efforts now: we must eradicate all remaining strains of all polioviruses.
"We do have good news from Africa: no wild poliovirus type 1 has been detected anywhere on the continent since 2016 in the face of ever improving surveillance."
polio vaccination WHO
Previous 'Medicine safety is in the DNA of pharmacists.'
Next One in eight: tobacco fatalities in Australia
20 million miss out
Pertussis adapts to boost its survival
Person with measles visits pharmacy


The News Corporation appeared tantalizingly close to succeeding in its bid to acquire Dow Jones & Company.
The News Corporation appeared tantalizingly close to winning the support of enough members of the Bancroft family to succeed in its bid to acquire Dow Jones & Company last night, but not close enough to conclusively claim victory.
Family members and trusts representing more than 30 percent of the shareholder vote — enough to put the deal over the top — indicated to their lawyers that they would support the bid, but some of them had not yet delivered signed commitments and could still back away, according to people briefed on the matter, who asked not to be identified because they were not authorized to discuss it.
Late last night, bankers on both sides said that the Bancrofts' chief lawyer, Michael B. Elefante, who was canvassing the family members, still had not given them a precise count of votes committed and those still pending. Some votes appeared to be held up by last-minute negotiations over a side issue — who would pay the fees of the bankers and lawyers advising the family and its various trusts.
The News Corporation has not said how many firmly committed votes it needs from the family before it will be confident enough in the outcome to proceed; people involved in the negotiations put the minimum figure at 30 to 34 percent of the overall shareholder vote.
The Ottaway family, longtime junior partners in Dow Jones, hold 7 percent of the shareholder vote and are opposed to the deal, and the Bancrofts, with 64 percent, were deeply divided, with a set of alliances that continued shifting until the last day.
That leaves 29 percent of the vote in outside hands, the great majority of which is expected to favor the deal. But it is hard to predict what fraction will vote against, and how many shareholders simply will not vote — making it equally hard to be certain how many Bancroft shares the News Corporation needed.
The $5 billion, $60-a-share takeover would give Mr. Murdoch one of the world's great media trophy properties and a larger voice in national affairs. It would also provide a ready source of material and credibility for his newest big gamble, the Fox Business Channel, which he plans to start in October.
Dow Jones's centerpiece is The Wall Street Journal, with domestic circulation of more than two million six days a week, second only to USA Today, but the company also has many other parts, like Barron's magazine, Dow Jones Newswires, the MarketWatch Web site and Factiva, an electronic news archive and information service.
The byzantine takeover fight, which has already dragged on for four months, took several more unorthodox turns yesterday.
Last night, well after the 5 p.m. Eastern deadline for the Bancroft votes to be delivered to the family's Boston law firm, Hemenway & Barnes, there was still no firm answer from one set of family trusts.
Those trusts are controlled by another set of the family's lawyers, based in Denver, who were seeking a higher price for the supervoting Class B shares, which are owned primarily by the Bancrofts. Dow Jones management has firmly opposed such a premium.
Another complication emerged yesterday as those Denver trusts sought to have Dow Jones pay their fees and expenses for advisers and lawyers, which could run into the millions of dollars, according to people involved in the talks.
The Denver trusts and several others have suggested that by having the company pay the family's fees and expenses, they would effectively receive a differential price.
Some people involved in the talks suggested that if Dow Jones were willing to pay the fees and expenses, some of the trusts would most likely vote in favor of the deal.
Complicating the situation further was the revelation that Merrill Lynch, which had been representing the family on behalf of the Boston-based branch, had struck a deal for Dow Jones to pay its expenses, while advisers to other parts of the family had no such arrangement.
The arrangement with Merrill Lynch had some family members up in arms yesterday, claiming that it was a conflict of interest because Merrill Lynch had made repeated presentations to the entire family and was supposed to be unbiased.
The Denver faction, controlling 9 percent of the shareholder vote, is crucial to the deal — it is the only large bloc that wants to sell, but has been holding out for a higher price. If it can be won over, that would almost certainly give Mr. Murdoch enough confidence that he has a majority to proceed with a shareholder vote.
The history of the News Corporation's takeover attempt has been one of the most convoluted in recent memory. The Bancrofts at first declined to respond to the offer, then rejected it out of hand and did not reply to Mr. Murdoch's missives, and then finally agreed to talk with him.
The result was essentially a three-way negotiation, with the Dow Jones board, the News Corporation and the Bancrofts looking for common ground. Meanwhile, the family hashed out its own internal disputes, with some members wavering and others changing sides outright, making it difficult all along to take a reliable reading of its intentions.
The family won an agreement to limit Mr. Murdoch's control of the Journal's newsroom and its pages, but it did not go as far as the arrangement they originally demanded.
Experts in trusts and estates said that if the Bancrofts rejected the offer, it might lead to a flurry of lawsuits pitting family members against each other. They said that people who wanted to sell but had little or no voting power over their shares could have strong cases against trustees — whether family members or not — who voted against the deal.
Donald A. Hamburg, a trusts and estates lawyer at the firm Golenbock, Eiseman, Assor, Bell & Peskoe, said that "the answer to every trust question lies in the wording of the particular trust," and there could be provisions in the Bancroft trusts that give the trustees particular powers to do as they see fit.
But as a general matter, he said, "a trustee has to vote in the best interests of the entire group of beneficiaries," and turning down a windfall could easily be seen as a violation of that principle. Even younger members of the family who are not current beneficiaries, but would inherit interests in the trusts, would have standing to sue, he said.
In The Journal's central newsroom in the World Financial Center, according to reporters working there, there was an eerie silence late Monday afternoon, as people nervously awaited an answer and many of them obsessively checked the internal "News Edge" wires system for news.
Similar scenes played out in the paper's Washington and Los Angeles bureaus, with several reporters and editors saying the apprehensive feeling in the air was because of concerns about Mr. Murdoch as well as the worry that Dow Jones would be even more vulnerable if the deal collapsed.
The nail-biting played out against increasing newsroom tension between those who favor the sale and those who do not. Several reporters in the paper's Pursuits and Weekend Journal sections said they were furious that their editors had been talking favorably about life under the News Corporation.
To the last, people inside and outside Dow Jones who opposed the sale were trying to arrange alternative deals that would allow some Bancroft family members to sell and others to keep control of the company. Brad Greenspan, an Internet entrepreneur, said that in the last few days, he arranged conversations between one of his tentative backers for such a bid, Intel Capital, and Leslie Hill, a family member who sits on the Dow Jones board.
Mr. Murdoch has said he wants to invest in The Journal and beef up its national affairs coverage, diluting its traditional emphasis on business news, and its European and Asian editions, making it a tougher competitor for The New York Times and The Financial Times. That could mean losing money in the short run, something Mr. Murdoch has always been willing to do with certain properties.
Mr. Murdoch first made his offer to Dow Jones's chief executive, Richard F. Zannino, over breakfast on March 29, and made a formal, written bid to the board on April 17, but news of the offer did not break until May 1.
On May 2, Mr. Zannino made a presentation to the Dow Jones board that made it seem to many of them that the company's prospects on its own were poor and that he favored a sale. He later insisted that he had not meant to give those impressions, but even so, the presentation had a sobering effect, and most of the board clearly thought that Mr. Murdoch's $60-a-share offer was simply too good to pass up.
That breakfast with Mr. Murdoch set in motion a long struggle within the Bancroft family. Factions formed and dissolved, and momentum swung widely as family members changed sides, children were pitted against parents and, in some cases, siblings opposed each other.
For a private, reserved clan that had long frowned on confrontation or aggressive involvement in the company's affairs, it was a long, uncomfortable conflict, played out with the news media trying to dissect their personalities and rivalries. And for much of that time, shareholders and executives at both companies could do little but watch and wait as the family labored to reach a conclusion.