Bring back your natural shine with this jet stream of stain busting power.
Our Friendly hygienists will polish up your dental hygiene & keep a close eye on your oral health.
Our qualified hygienists love making sure your teeth are nice and clean, but that's not all they do – they are also excellent dental educators and keep a watchful eye on your oral health. They inspect your gums for any signs of disease and also offer potentially life-saving mouth cancer screening.
Benefits of regular visits to our Dentist Huddersfield hygienists?
What do our hygienists offer?
Dental hygiene can have a significant effect on the rest of your body too. Poor gum health and periodontal disease have been linked to a number of diseases such as heart disease and diabetes, so it pays to see our hygienists regularly and make sure your mouth is as clean as can be.
Unregistered patients can visit the hygienists without the need to see the dentist.
A popular treatment with all our regular members, the Dentist Huddersfield Airflow system uses a focused jet of water, air and bicarbonate particles to gently polish away surface stains such as those caused by coffee, red wine and smoking.
Unregistered patients can visit the hygienists for an Airflow without the need to see the dentist.


Kuda Hitam Express 2 Links - Be the first to arrive in Lombok!
Located in the remote fishing village of Amed (East Bali) is the best place to begin your exploration of this magical island both above and below the water. Owned by a PADI Master Instructor/SSI Instructor Trainer with over 35 years diving experience, including 15 years in Indonesia, and a team of local dive masters. We offer dive trips to the best sites in Bali in addition to a full range of courses from Open Water to Instructor.


text:
AB AC AD AE AG AK AM AO AQ AS AT AW AX AZ BM BT BU
CE CM CS CT DC DK DM DP DS DT EA EM EN EO ET EW
FC FT GM GS (53-61) GS (78-Now) HM HT IC IM IS IT JO LI LN LS
MA (48-67) MA (72-Now) ME ML MM MN MR MS MT MU NAVY NC ND OM OS OT
PC PH PM PN PR QM RD (WW2) RD (48-72) RM SD SF SH SK SM
SO ST SV SW TM UT WT YN NAVY DIVER
U.S.S. WILLIAM R. RUSH
PRO PATRIA CONTENDIMOS
FOR COUNTRY WE RUSH
USS WILLIAM R. RUSH (DD-714) - a Gearing-class destroyer
OCT 1944 - Keel Date: 19 OCT 1944
JUL 1945 - Launch Date: 8 JUL 1945
SEP 1945 - Commissioned: 21 SEP 1945
DEC 1945 - JAN 1959 Commisioning
JAN 1951 - JAN 1951 Realm of the Golden Dragon
OCT 1962 - OCT 1962 Cuban Missle Blockade
OCT 1964 - Shellback Initiation - 21 OCT 1964 - Pacific Ocean
JAN 1967 - JUL 1967 Mediterranean-Indian Ocean-Persian Gulf
APR 1972 - OCT 1972 Circumnavigation
APR 1972 - OCT 1972 Panama Canal
APR 1972 - Shellback Initiation - 15 APR 1972 - Atlantic Ocean
APR 1972 - OCT 1972 West Pac-Viet Nam
JUL 1978 - Decommissioned: 1 JUL 1978
Class: Gearing-class destroyer
Flank Speed: 35 kt
USS WILLIAM R. RUSH (DD-714)
William R. Rush (DD-714) was laid down on 15 October 1944 at Newark N.J. by the Federal Shipbuilding and Drydock Co.; launched on 8 July 1945; sponsored by Mrs. Dorothy Flagg Biddle a cousin of Capt. Rush; and commissioned on 21 September 1945 Comdr. Theodore E. Vogeley in command.
After fitting out at the New York Navy Yard and shakedown training out of Guantanamo Bay and Casco Bay Maine William R. Rush took part in 8th Fleet maneuvers off the eastern seaboard into May of 1946. The destroyer then moved southward to Pensacola Fla. where she served as a plane guard for Ranger (CV-4) as the veteran carrier conducted flight training operations. Arriving back at Newport R.I. her home port on 28 July William R. Rush spent the rest of the year in local operations.
The destroyer departed Newport on 9 February 1947 bound for Europe and her first overseas deployment. She touched at ports of call in England Ireland Norway France Germany Denmark French Morocco and Gibraltar before returning to Newport in June. For the next two years William R. Rush operated off the eastern seaboard exercising with submarines and escorting and planeguarding for carriers.
In July 1949 William R. Rush sailed for Europe for an extended European and Mediterranean deployment that lasted into the following year. She touched at ports in France Greece Crete Turkey Gibraltar England Scotland and Belgium before she returned to Newport. Subsequently overhauled for three months at Boston the destroyer carried out refresher training in Guantanamo Bay from May into July 1950. Commencing in mid-July William R. Rush conducted a training cruise that took the warship and her embarked midshipmen from Halifax Nova Scotia to Guantanamo Bay.
Returning to Newport on 1 September 1950 William R. Rush visited Argentia and St. Johns Newfoundland during October spent much of the following month engaged in Operation "Convex I" a convoy and striking force exercise and underwent a period of upkeep back in her homeport preparing for her next extended deployment.
On 3 January 1951 William R. Rush sailed for the Far East. Steaming via the Panama Canal Pearl Harbor Midway and Sasebo Japan the destroyer subsequently joined Task Force (TF) 77 in Korean waters and conducted her first shore bombardment mission on 7 February shelling North Korean rail lines along the coast. Bombardment and escort missions kept the ship continuously occupied until 13 June when she began her voyage to the United States steaming via the Indian Ocean the Suez Canal the Mediterranean and the North Atlantic.
William R. Rush completed her circumnavigation of the globe when she returned to Newport on 8 August 1951. She spent the rest of 1951 on maneuvers and exercises from her home port before she entered the Boston Naval Shipyard at the end of the year for conversion to a radar picket ship. The ensuing refit during which she was decommissioned on 21 December 1951 entailed replacing the ship's 40 millimeter Bofors batteries with rapid-fire 3-inch mounts; removing her torpedo tubes; and receiving improved electronic and radar equipment to enable the ship to perform her new picket role itself an outgrowth of World War II experience with kamikazes in the Pacific. Reclassified to DDR-714 on 18 July 1952 William R. Rush was recommissioned on 3 September 1952 Comdr. N. B. MacIntosh in command.
Returning to Newport from her shakedown cruise as a DDR soon thereafter William R. Rush underwent refresher training in Guantanamo Bay before she called at Mobile Bay Ala. for the 1953 Mardi Gras festivities.
William R. Rush conducted her second 6th Fleet deployment from April to October and then operated locally out of Newport. She performed varying duties into the summer of the following year carrying out in succession: antisubmarine warfare (ASW) exercises plane-guard duties with carriers; and a tour as engineering school ship for the Atlantic Fleet Destroyer Force She next embarked 66 NROTC midshipmen and sailed for the British Isles touching at Irish and British ports before she returned to Guantanamo Bay for training. Disembarking the midshipmen at Norfolk on 3 September 1954 William R. Rush soon thereafter shifted to Boston for a three month overhaul.
Over the next decade from 1954 to 1964 William R. Rush was deployed to the Mediterranean for tours of duty with the 6th Fleet on eight occasions touching at ports that ranged from Gibraltar to Beirut Lebanon and including Pollensa Bay and Palma Majorca; Naples and Leghorn Italy; Athens and Salonika Greece Golfe Juan France Barcelona and Rota Spain. During her service with the 6th Fleet William R. Rush operated as plane guard and radar picket for fast carrier task forces and participated in NATO exercises. There were highlights of the cruises: in 1955 while at Golfe Juan the destroyer hosted Mrs. James J. Cabot the daughter of Capt. William R. Rush; and in 1957 the ship cruised the Mediterranean with Naval Academy midshipmen embarked.
In between the Mediterranean deployments William R. Rush operated from the Arctic Circle to the Caribbean homeported first at Newport from 1954 to 1958 and then from Mayport Fla. from 1958 to 1964. She twice penetrated north of the Arctic Circle in the autumn of 1957 and late in 1960 both times on NATO exercises.
There were highlights of the ship's closer-to-home deployments as well. In the summer of 1960 the ship embarked 35 Naval Academy midshipmen and took part in operations off the eastern seaboard with the Atlantic Fleet. She visited Quebec Canada Hamilton Bermuda; and Poughkeepsie N.Y. during the cruise. That autumn the ship served on "barrier patrol" when Cuban Premier Fidel Castro threatened the Caribbean nations of Nicaragua and Honduras. Two years later in the fall of 1962 after American reconnaissance planes discovered the presence of Soviet offensive missiles in Cuba William R. Rush returned to the area and operated with TF 135 on the Cuban "quarantine" line from 20 October to 3 December. The ship was at sea continuously during that period except for an availability alongside the destroyer tender Yosemite (AD-19) from 12 to 17 November.
William R. Rush departed Mayport on 22 June 1964 and arrived at the New York Naval Shipyard on the 26th. Once at the shipyard the ship commenced a 10 month Fleet Rehabilitation and Modernization (FRAM) overhaul at the completion of which she would resume her old classification DD-714.
William R. Rush departed New York on 30 April 1965. Homeported back at Newport the modernized destroyer soon commenced regular operations with the Fleet following essentially the same sort of schedule that she had pursued since commissioning in 1945.
As a member of Destroyer Squadron (DesRon) 10 she operated off the eastern seaboard between Newport and Key West Fla. assuming a new role as an antisubmarine warfare ship. Returning to Newport on 27 July 1965 from refresher training out of Guantanamo Bay and a week of providing services to the Fleet Sonar School at Key West William R. Rush embarked 25 NROTC midshipmen for three weeks at sea with Canadian Navy units on exercise "CANUS (Canadian and United States) SILEX 1-65."
The ship then went back to Newport for availability alongside Yosemite and then conducted two weeks of type training before moving south to Key West for a month of Sonar School services. A highlight of that deployment to Florida coastal waters came in September when she rescued seven Cuban nationals who had originally been bound back to Cuba to bring out relatives. Their two boats had developed engine trouble and were in danger of capsizing in heavy seas.
William R. Rush returned to Newport shortly before Thanksgiving of 1965 and spent the remainder of the year in home waters before getting underway on 14 February 1966 for the Mediterranean. Highlighting the ship's 10th Mediterranean deployment were the usual good will stops at ports in Italy Rhodes Sicily and Turkey; ASW exercises with American and Spanish Navy units including Exercise "Spanex I-66"; and 6th Fleet antiaircraft and ASW maneuvers. Relieved on 21 June at Gibraltar the destroyer returned to the east coast of the United States.
William R. Rush spent the remainder of 1966 on operations off the eastern seaboard ranging from Newport to the Virginia capes pursuing a well-rounded slate of exercises including among others such areas as gunfire support and ASW. Early in 1967 the ship enhanced her capabilities as an ASW destroyer by receiving two Destroyer Antisubmarine Helicopters (DASH) and becoming fully qualified in DASH operations.
William R. Rush departed Newport on 1 March 1967 and crossed the Atlantic in company with Galveston (CLG-3). The destroyer subsequently called at Gibraltar Sardinia and Athens before transiting the Suez Canal on 1 April. She relieved Steinaker (DD-863) the following day at Port Suez. William R. Rush then set course for Bahrain a small island in the Persian Gulf off the coast of Saudi Arabia. En route the destroyer was fueled from the French oiler Aritrea at Massawa Ethiopia on 6 April.
Arriving at Bahrain on 13 April William R. Rush joined Valcour (AGF-1) the flagship of Rear Admiral E. R. Eastwold Commander Middle East Forces (MidEastFor). In the ensuing weeks the destroyer on her first MidEastFor deployment visited Al Misirah a small island off the coast of Oman where the British Royal Air Force maintained a small logistics airfield; Karachi Pakistan and Massawa for a fuel stop. William R. Rush returned to Port Suez on 21 May and was relieved there by Fiske (DD-842).
The next day William R. Rush transited the Suez Canal on her way back to the Mediterranean. At that time tension was great in the Suez since the President of the United Arab Republic Gamal Abdel Nasser had demanded on 17 May that the United Nations Expeditionary Force (UNEF) be withdrawn from Egypt and the Gaza Strip posthaste. On the 20th Egypt began patrolling Israel's coast.
The growing aura of uneasiness in the Middle East was noticeable. The destroyer's commanding officer subsequently reported: "As (William R.) Rush passed through the Canal we could feel an atmosphere of tension all about us gun emplacements and troops were obvious on both sides of the Canal."
Over the next few days the situation worsened. Meanwhile William R. Rush moored alongside Tidewater (AD-31) where she spent the first few days of June undergoing a tender availability. However the outbreak of full-scale war between Israel and her Arab neighbors on 5 June meant a hurried deployment seaward.
The destroyer operated with 6th Fleet units as they conducted emergency contingency force operations until the 17th. She subsequently called at Istanbul from 21 to 26 June before serving as plane guard and picket for America (CVA-66) south of Crete. The destroyer later touched at Kavalla Greece and Sardinia and Rota homeward bound. She finally reached Newport on 20 July ending the eventful deployment.
That autumn William R. Rush operated off the coast of Florida aiding the Fleet Sonar School in training officers and participating in ASW exercises. She then enjoyed a period of leave and upkeep at her home port to round out the year.
Late in January 1968 William R. Rush operated out of Newport as school ship for the Naval Destroyer School. In mid-March she continued her training oriented activities when she embarked 32 prospective destroyer officers and sailed for the Caribbean in company with Gainard (DD-706) and Glennon (DD-840). During that cruise she visited St. Croix Virgin Islands and San Juan Puerto Rico. Soon after the ship returned to her home port she shifted to the Boston Naval Shipyard for a four-month overhaul.
Over the next 11 years William R. Rush conducted two more Mediterranean deployments in early 1960 and from the autumn of 1970 to the spring of 1971 in between which she operated as before off the eastern seaboard and into the Caribbean. Ports visited with the 6th Fleet included Rota and Barcelona Spain Piraeus Greece Venice Genoa and San Remo Itaiy Sfax Tunisia; and Valetta Malta. A social highlight of the 1969 deployment was when the officers and men of the ship were hosted royally on three separate occasions by Contessa Catherine Rush Visconti-Prasca the daughter of the ship's namesake at her villa.
During that deployment the ship participated in the usual slate of maneuvers and exercises including stints planeguarding for Forrestal (CVA-59) and John F. Kennedy (CVA-67) and taking part in NATO Exercise "Dawn Patrol." Returning home William R. Rush visited Liverpool England and Oslo Norway and then spent a grueling period in the North Atlantic operating on occasion north of the Arctic Circle again with a hunter-killer group tasked with perfecting ASW tactics. For her part in that significant evolution operating in company with Wasp (CVS-18) William R. Rush received the Meritorious Unit Commendation.
January 1971 William R. Rush departed Naples and over the next 26 days shadowed the Soviet helicopter carrier Leningrad in the Gulf of Sollum gathering new and noteworthy intelligence data on that ship and her operations. Following that event the destroyer resumed her other duties ultimately returning home to Newport on 2 May 1971.
On 5 April 1972 William R. Rush in company with Charles H Roan (DD-853) departed Newport for her last extended deployment under the Stars and Stripes bound for the Middle East and Indian Ocean. En route the ship visited Port-au-Spain Trinidad Recife Brazil Luanda Angola and Lourenco Marques Mozambique before arriving at Port Louis Mauritius on 11 May. William R. Rush subsequently stopped at Moroni Grand Comoro Comores Islands Mombasa Kenya Karachi Pakistan and Kharg Island off the coast of Iran. Additionally the ship spent a two-week upkeep period at the MidEastFor home port Bahrain where she was visited by the Honorable William P. Rogers the Secretary of State on 3 July. She later called at Dammam Saudi Arabia where she embarked 19 Royal Saudi Naval Force officers for underway training from 15 to 19 July.
A Red Sea excursion took William R. Rush to Massawa and return visits to Mombasa Port Louis and Bahrain. In the course of the deployment and during transits between ports William R. Rush twice conducted surveillance operations at Russian naval anchorages near Socotra Island and Cape Guardafui and once at Coetivy Island.
During the time spent operating under the aegis of Commander MidEastFor William R. Rush operated primarily as an ambassador of good will "showing the flag" in an area where the Soviet Union's naval presence was becoming more marked.
Ultimately after conducting exercises with Charles H. Roan and the British frigate HMS Lowestoft William R. Rush departed Bahrain. She continued her circumnavigation of the globe with visits to the ports of Karachi Pakistan; Colombo Sri Lanka; Singapore; Hong Kong Yokosuka Japan; Midway; Pearl Harbor; San Diego and the Panama Canal before she arrived back at Newport on 31 October 1972.
William R. Rush subsequently operated out Newport on local operations into March of 1973. Then after an overhaul at the Boston Naval Shipyard William R. Rush was assigned to DesRon 28 on 2 July 1973 for service as a Naval Reserve training ship.
Homeported at Fort Schuyler Bronx N.Y. William R. Rush spent the next five years training selected reserve crews and operating between the Virginia capes Operating Area and Halifax Nova Scotia.
William R. Rush was decommissioned at Fort Schuyler on 1 July 1978 and was simultaneously struck from the Navy list. Transferred that same day to the navy of the Republic of Korea (ROK) under the terms of the Security Assistance Program the destroyer became ROKS Kang Won (DD-922) and operated with the South Korean Navy into 1979.
[Note: The above USS WILLIAM R. RUSH (DD-714) history may or may not contain text provided by crew members of the USS WILLIAM R. RUSH (DD-714) or by other non-crew members and text from the Dictionary of American Naval Fighting Ships]

redpajama_set_name: RedPajamaCommonCrawl


text:
Q: hasManyThrough relations ships with join? I have 4 tables (Cars, Vignettes, Inspections and Insurances). Vignettes, Inspections and Insurances are "belongsTo" to Cars.
I need to combine results of these three tables into one query and sorting by 'created_at' and take first 3-4 of them. How can I achieve that?
All of the three tables have same column names and types

A: You should be able to chain things together, something like
$car->with('Vignettes')
 ->orderBy('created_at', 'desc)
 ->take(4)
 ->get();

As with everything laravel, the docs are your friend.

redpajama_set_name: RedPajamaStackExchange


When the lease ends it is most likely that the lessee will be required to take out all of their fixtures and fittings, and 'make good' any damage caused during their occupancy and/or in removing their fixtures and fittings. Irrespective of how new, nice, reusable or expensive a fit-out may be, most leases will require a lessee to remove it at their own cost (which is often not insubstantial). If a lessee does not remove their fixtures and fittings on time, they are most likely to become the property of the lessor, and the lessor can, at the lessee's expense, attend to the make good.
Some leases oblige the lessee to pay rent as though it was holding over until it has complied with its make-good obligations in full. Depending on the precise wording of such leases, this can enable lessors to rely upon immaterial errors by the lessee in complying with its make-good obligations as an excuse to continue to charge the departed lessee full rent while the lessor finds a replacement lessee.
Lessees should be wary about sub-letting premises for the balance of a lease term, as this can leave them with insufficient time at the end of the sub-lease to comply with their own make-good obligations.
Lessors' standard leases rarely oblige lessors to keep the building structurally sound and weatherproof. In the absence of such an obligation, circumstances can arise under which it is very difficult for the lessee to comply with its general repair obligations.
Some lessors may be willing to grant a lessee an option to pay a pre-determined 'make-good amount' in lieu of performing an end-of-tenancy make-good of the premises. This provides the lessee with the flexibility to continue to carry on its business in the premises until the end of the lease term, if they would prefer that over vacating early and continuing to pay rent while the make-good is being performed.
Contact us so we can help you to understand and meet your requirements to 'make good' under your lease.


Dress code: Proper golf attire is required at all times.
Credit cards accepted: Major credit cards are accepted.
Outstanding from start to finish. This is a must play for any golfer. You are treated to a course and experience worth the money. Course is one of the best I have played.


Catch up on all the latest updates from HTL Group; Read our most recent press releases, view our latest training courses, discover useful hints and tips, learn about our innovative product solutions as well as find where you can meet us at upcoming industry events and exhibitions.
Good Luck Ponteland United Blackbirds!
Introducing the HTL Run Down Simulator!


As coffee lovers ourselves, we decided to fill this year's holiday gift guide with our favourite items or things that are on our wish lists.
Doi Chaang Wild Civet Coffee – Cup notes of macadamia nut, milk chocolate & lemon. The rarest coffee in the world can be purchased for $5.00 off until Christmas! Use code "civetlove" at checkout.
Brew Better Coffee at Home – The perfect book for both the beginner and the home-brew nerd. Bonus: Looks great on the coffee table.
KeepCup – The KeepCup is a favourite around the office. Not only are you gifting a stylish, practical mug, you're keeping takeout cups out of the landfills!
Doi Chaang "Warm the Moment" Diner Mug – This heavy-duty, cosy diner mug is only $12.99. Perfect for the ethical coffee lover (or tea drinker!).
Aerobie Aeropress – We brew Buzzin' with this every morning. Compact, affordable, and brews one mean cup of coffee.
Airscape Coffee Container – Having fresh beans is essential to brewing great tasting coffee. We use Airscapes in the office to make sure our beans stay as fresh as possible for as long as possible!
Hopwired – This is an event we definitely won't be missing. Gift tickets to Hopwired coffee and coffee beer festival, happening in February!
Baratza Encore Grinder – Lauded by coffee experts as THE go-to entry level grinder for those brewing coffee at home – and one of our personal favourites.


text:
How Honda unlocked its shock MotoGP star's speed
By Simon Patterson
One of the surprise stories of the 2020 MotoGP season so far has been the pace of LCR Honda rider Taka Nakagami.
At the start of the year, he had just two top-six finishes to show for his first two campaigns at the top level.
But the 28-year-old Japanese racer used impressive consistency to become a title contender in 2020 until it all went wrong at last weekend's Teruel Grand Prix at Aragon.
Finishing between fourth and ninth in each of the first 10 races of the season, he was fifth in the championship – 29 away from leader Joan Mir in this ultra-volatile title race – when he lined up on pole last Sunday.
Nakagami: 'Incredible pressure' led to 'stupid mistake'
The first-lap fall that dropped Nakagami to seventh in the standings doesn't stop him being one of the stars of the year so far.
And if anything caused that Aragon crash, it was his inexperience at being at the front of MotoGP battles. He's still to lead a lap in the premier class or even finish on the podium and he admitted after the race last Sunday that the pressure played a key role in his fall.
But that's not taking away from his turnaround in form so far this year. His progress has left many scratching their heads and asking what has changed so much for him in only a few short months.
However, speaking exclusively to The Race, Honda Racing Corporation technical manager Takeo Yokoyama says that his rider's pace has come as no huge surprise to him given how much effort he saw Nakagami put into his pre-season preparations.
"We had a very serious meeting where we told him that he has to do more, because at the stage of his career he was at, he could have destroyed it" :: Takeo Yokoyama
"Even during the lockdown period," the veteran engineer admitted, "he was always trying to be prepared, ready, for whenever the start of the season might be. He was trying to always be focused, both physically and mentally.
"We went one or two times together to Motegi with the streetbike – it was only a streetbike but better than nothing for his physical training. That was the first thing."
Despite those better-than-ever preparations ahead of the delayed start of the year, the real change didn't come until after the season had started, according to Yokoyama.
"The second thing came at Jerez, at the first race. He wasn't riding very well, he only finished inside the top 10. We knew that he likes Jerez and he's normally very fast there, so we were looking for a really good result.
"We told him that he was lucky to start the season at his favourite track, and we wanted to go full gas from the start. In the first race he wasn't very fast and he was disappointed but I was even more disappointed.
"After the race, we had a very serious meeting where we told him that he has to do more, because at the stage of his career he was at, he could have destroyed it.
"He had to do more, I had to do more for him, and we had to work together to do it."
That left Nakagami in a dangerous position as well, as he prepared to negotiate a now-completed contract extension with HRC.
The changes needed to help Nakagami succeed didn't come down to good fortune, but bad luck for others has helped.
Suddenly inheriting the title of lead Honda rider for round two after injuries sustained by both Marc Marquez and Cal Crutchlow, Nakagami has admitted before that the added input from Yokoyama's team was a contributing factor to his upturn – something that the chief engineer agrees with.
"We never meant to go in a different way from what Marc would suggest, but probably unconsciously we've done things in a different way" :: Takeo Yokoyama
"I could see that his mood changed after that, but so did his riding style," said Yokoyama.
"We worked more together, we showed him the data from previous years, and he was able to see what Marc does.
"We worked on every single detail, and already in the second race in Jerez he was able to make improvements."
With his future now secure and with two 2021-spec bikes set to be in his garage next year (the first time he won't start the season on year-old machines), Nakagami has had an added bonus from his time as top Honda: the chance to steer development towards a more rider-friendly bike.
Honda's over-reliance on Marquez is about to bite it hard
Honda has been dominated in recent seasons by Marc Marquez and his incredible talent. Yokoyama told The Race that there has been a change in the firm's thinking that could have some big benefits for the other Honda riders next season.
"When Honda has an incredible champion, our philosophy is to adapt the bike more and more to them," he admitted.
"That's what we've been doing for the past seven years – and then suddenly that brief was gone.
"We weren't lost, but we had to reflect on what we were doing because the riding style of the others is different.
"So it was a good moment for us to sit down with all the engineers and think about what areas we had to work on without Marc.
"We had to take the maximum from what we had: the bike, the tyre, the rider line-up. It was challenging but it was quite refreshing.
"If I imagine Marc hadn't got injured at the start of the season, maybe I can imagine that the bike of today wouldn't be the same.
"We follow the feedback from the existing riders – Cal, Taka and Alex [Marquez] – and we never meant to go in a different way from what Marc would suggest, but probably unconsciously we've done things in a different way.
"I don't think he'll come back tomorrow, get on Alex's bike and say 'this isn't my bike'. He'll be faster than he was in Jerez, because what we've been working on is what the bike, the tyres, the track layouts require.
"Will the bike be less aggressive? Probably 50% yes, 50% no."
MotoGP cancels Sepang test due to state of emergency
Hospital check-up shows extent of Marquez's recovery
MotoGP series organiser Dorna has reworked the schedule for the start of the 2021 championship following the cancellation of the planned first pre-season test at Sepang
21 hours ago No Comments
The riders hit hardest by MotoGP test cancellation
MotoGP doesn't intend to replace its cancelled Sepang test, meaning a drastic cut in winter running. Who does that hurt most, and who actually gains from it? Simon Patterson investigates
Jan 14 2021 No Comments
KTM becomes first MotoGP manufacturer to sign up through 2026
KTM has become the first MotoGP manufacturer to officially sign on to the series through to 2026, following an ultra-successful 2020 season
Dovizioso revelations add to pressure on Ducati MotoGP boss
Andrea Dovizioso's claim that Ducati MotoGP tech chief Gigi Dall'Igna forced him out of the team piles pressure on Dall'igna in the team's post-Dovi era
Podcast: Each MotoGP manufacturer's tech agenda for 2021
The first episode of The Race MotoGP Podcast in 2021 is a tech special looking in-depth at what each manufacturer needs to improve on this season
MotoGP team boss Gresini 'improving' amid COVID fight
MotoGP team owner Fausto Gresini has regained consciousness and his condition is "improving" amid his battle with COVID-19, according to a statement from his team
What will Red Bull's 'not a Honda' F1 engine be called?
22 hours ago Formula 1 38 Comments


There were four applicants for the .MED new gTLD.
As published on the TMCH website: ".med is the intersection of global clinical excellence with advanced technology to create the most trusted and respected healthcare community on the Internet".
SUNRISE PERIOD END: Friday, 24 June, 2016.
Parties interested in registering a ".med" domain name can contact the Nameshield Group to participate in the Sunrise Period.


Aloha Cluster Pays Slot is a NetEnt online slot that's named after one of the most commonly recognised words in the Hawaiian dictionary that's used to say hello or goodbye to someone. This upbeat slot offers you a little piece of paradise on the sun-drenched island of Hawaii, where the ancient Tiki gods are waiting to shower you with wins. The game, whose full title is Aloha Cluster Pays – includes Free Spins with Symbol Drops, Sticky Win Re-Spins, and the exciting Cluster Pays pay structure.
Aloha differs from the majority of online slot games in that it has six reels rather than five. Normal paylines are thrown out of the window, as the Cluster Pays Feature allows you to create winning combos anywhere on the reels whenever nine or more of the same symbol appears in a cluster (N.B., a symbol forms part of a cluster if it's vertically or horizontally adjacent to the same type of symbol). The slot allows for bets of between 10p and £200 per spin, and the RTP (Expected Return to Player Rate) is 96.42%.
As well as being able to set the Coin Value between 0.01 and 2.00, you can also choose a Bet Level from 1 to 10. In addition, the game includes an Auto Play facility, which lets you play hands-free for a pre-determined number of spins.
The graphics and sound effects of Aloha really make you feel like you're on holiday on the popular tropical island. In the background, there's a volcano gently wafting white smoke into the air, and in the foreground, there's an azure blue pool surrounded by palm trees and exotic flowers while a carved statue of a grinning Tiki god sits smiling on the right-hand side. The cheerful and laidback Hawaiian music soothes all your cares away while you concentrate on enjoying the game.
There are nine paytable symbols which include a question mark, a postage stamp, three Tiki masks (green, blue, and red), clam shells, orchids, coconuts, and pineapples. The Question Mark is the wild symbol, and it can substitute for all symbols except the Postage Stamp.
The Postage Stamp is the scatter symbol and it unlocks the Free Spins Feature when it appears three or more times on the same spin. Depending on how many scatters trigger the feature, you get at least nine free games and as many as twelve. Plus, you can gain further free games with additional scatters. The Free Spins Bonus also makes use of the Symbol Drop mechanic, which removes low-value symbols to allow for bigger wins.
The Sticky Win Re-Spins Feature of the Aloha slot can be randomly activated following a cluster win. It holds all winning symbols while re-spinning the remaining symbols, and if a bigger cluster win is created, you get a further re-spin.


English Oak (foreground) and Cork Oak (rear) in front of John Macarthur's Hambledon Cottage. These trees were amongst many John Macarthur brought back from England in 1817 on the "Lord Eldon".
Volunteer guide telling the story of a lady who lived at the Parramatta Female Factory.
Searching the list of 5000 ladies researched to date.
View from Withdrawing Room, showing Card Table with a Whist hand in progress and the Davenport Desk with John Macarthur's photo above it, through to the Dining Room.
All tours through John Macarthur's Hambledon Cottage are by one of our experienced Guides.
Volunteer Guide conducting a group through the exhibition and cottage.
Hambledon Cottage was built by John Macarthur in 1824 on the grounds of his Elizabeth Farm Estate as additional accommodation for family and friends. It was home to many prominent Parramatta identities and is listed on the NSW State Heritage Register.
This elegant cottage is built of sandstock brick in the Colonial Georgian style and boasts a veranda enclosed by French doors and a beautiful, vaulted ceiling. It has been lovingly restored to this period. In the groiunds are many heritage-listed trees, some nearly 200 years old.
John Macarthur's Hambledon Cottage is presented as a house museum in the domestic style of the 1820s-1880s and contains many pieces of the era, some with Parramatta provenance.
Highlights of the collection include an 1836 Broadwood square piano, the Reverend Samuel Marsden's desk and a bed provenanced to Governor Fitzroy.
All tours through the museum are guided and visitors, young and old, can experience the 19th century lifestyle.


Online trade news source Nation's Restaurant News reports that a whopping 74 percent of American adults want laws compelling restaurants to post a nutritional analysis of every item listed on their menus or menu boards.
The survey, released this week by Technomic Inc., seems a little fishy. First of all, how does one create a complete nutritional analysis of every food and beverage offered without creating 15-page menus with all the graphic appeal of a Bulgarian phone book? Do 74 percent of all adults really want that? Secondly, who or what exactly is Technomic Inc.?
OK—a bit of Googling reveals that it seems to be a perfectly legit food-industry research firm with 40 years of experience. But still, the 74 percent figure may reveal a lot of internal disagreement and shades of gray when it gets run through the wringer of practical application in the real world. Not to mention lawsuits, of course: A New York City menu labeling law is already under legal fire from the New York State Restaurant Association.
How Often Do You Have to Eat Fish to Reap Its Health Benefits?


Recently we have given a online assignment to convert a prefix expression to postfix using binary tree. but it is very odd to say that we had learn tree only a day before. as a result only three or four of us among 30 could complete the code in 2 hours limited time. fortunately i was one of them. and for all of my friends who are struggling with it could see the following code.
Here is the code of prefix to binary tree(arrayed implementation).
This is my first post. Love the idea of Blogging. This is the best idea of shearing over the net.


text:
Hi5 Launching Crowd-sourced Translation Service for Hi5 and Apps
By Adweek Staff
While hi5 already has tremendous reach in South America, Europe, and Asia, apparently 23 languages are not enough. Starting today, hi5 is announcing the launch of its crowd-sourced translation service that will allow users to translate hi5 into any local language. In addition, hi5 will soon be making this service available to developers who want to translate their applications as well.
Since its launch earlier this year, Facebook Translations has spurred on significant international growth for the primarily English-speaking social network. While hi5 has been translating its site for a long time, the company hopes to push further down the long tail of languages around the world.
I sat down with Mukund Bhagavan, hi5's Director of Strategy & Operations, and Greg Holmes, hi5's Localization Manager, to discuss the details of the Hi5 translation program.
Mukund and Greg, With hi5 already professionally translated in so many languages, what is your vision for crowd-sourcing more translations of hi5?
Mukund: Our goal is to make hi5 accessible in all languages. Today, hi5 is available in 23 languages, but there is a long tail of languages we haven't yet started to reach in Eastern Europe, the Middle East, and the Indian subcontinent. We also want to expand our offering in Spanish speaking countries – today, we just have Castilian and Argentinian. We really want users to see hi5 as part of their local community.
Greg: For us, it's all about speed and quality of translations. As far as quality goes, authenticity and natural voice is important. For example, addressing all of the regional Spanishes is very important to us. There's a lot of pent up demand – we want to remove language as a barrier to hi5 usage.
So will you use a purely crowd-sourced model?
Greg: We've been incorporating feedback from our translation partner, Lionbridge, with whom we've been working for a long time. We'll keep working with them – they handle key parts of the translation, and create the glossary for volunteers.
As far as the volunteer experience goes, we're using an in-context translation model. Users can vote on others' translations, and once translations get enough votes, it goes to the editor for approval.
The hi5 user base is very international, but most developers can't afford to translate their apps into many languages. How will it work for developers who want to translate their apps on Hi5?
Greg: For developers, there's a similar in-context interaction model. The highest quality translations come in context. We want to make it as seamless as possible. We're working with the OpenSocial standards group to develop these particular standards further. Developers just have to meet the OpenSocial [i18n] spec for internationalizing their apps, and they will then be able to leverage the Hi5 translation community.
Thanks guys. Any last thoughts?
Mukund: The rollout is starting today, and will be live in the next several days. Our goal is to add 30 more languages this year. And tools will be available to the developer community soon.
http://adweek.it/2ksofZV
Here Are the 5 Ads Nominated for 2019's Outstanding Commercial Emmy


Students at Lysterfield PS are given opportunities to develop their leadership skills throughout their primary school years, culminating in formal leadership positions in Year 6.
These include School Captains, House Captains, Sustainability Leaders, Science and Technology Leaders and Student Voice Council Leaders. Selection is through a mixture of application, presentation and/or interview.


text:
Get Schistosoma essential facts below. View Videos or join the Schistosoma discussion. Add Schistosoma to your PopFlock.com topic list for future reference or share this resource on social media.
Schistosoma mansoni egg
Trematoda
Diplostomida
Schistosomatidae
Weinland, 1858
Schistosoma bomfordi
Schistosoma bovis
Schistosoma curassoni
Schistosoma datta
Schistosoma edwardiense
Schistosoma guineensis
Schistosoma harinasutai
Schistosoma hippopotami
Schistosoma incognitum
Schistosoma indicum
Schistosoma kisumuensis
Schistosoma leiperi
Schistosoma malayensis
Schistosoma margrebowiei
Schistosoma mattheei
Schistosoma ovuncatum
Schistosoma nasale
Schistosoma rodhaini
Schistosoma sinensium
Schistosoma spindale
Schistosoma turkestanicum
Schistosoma is a genus of trematodes, commonly known as blood flukes. They are parasitic flatworms responsible for a highly significant group of infections in humans termed schistosomiasis, which is considered by the World Health Organization as the second-most socioeconomically devastating parasitic disease (after malaria), with hundreds of millions infected worldwide.[1][2]
Adult flatworms parasitize blood capillaries of either the mesenteries or plexus of the bladder, depending on the infecting species. They are unique among trematodes and any other flatworms in that they are dioecious with distinct sexual dimorphism between male and female. Thousands of eggs are released and reach either the bladder or the intestine (according to the infecting species), and these are then excreted in urine or feces to fresh water. Larvae must then pass through an intermediate snail host, before the next larval stage of the parasite emerges that can infect a new mammalian host by directly penetrating the skin.
Electron micrograph of an adult male Schistosoma parasite worm. The bar (bottom left) represents a length of 500 ?m.
The origins of this genus remain unclear. For many years it was believed that this genus had an African origin, but DNA sequencing suggests that the species (S. edwardiense and S. hippopotami) that infect the hippo (Hippopotamus amphibius) could be basal. Since hippos were present in both Africa and Asia during the Cenozoic era the genus might have originated as parasites of hippos.[3] The original hosts for the South East Asian species were probably rodents.
Based on the phylogenetics of the host snails it seems likely that the genus evolved in Gondwana between 70 million years ago and 120 million years ago.[4]
The sister group to Schistosoma is a genus of elephant-infecting schistosomes -- Bivitellobilharzia.
The cattle, sheep, goat and cashmere goat parasite Orientobilharzia turkestanicum appears to be related to the African schistosomes.[5][6] This latter species has since been transferred to the genus Schistosoma.[7]
Within the haematobium group S. bovis and S. curassoni appear to be closely related as do S. leiperi and S. mattheei.[]
S. mansoni appears to have evolved in East Africa 0.43-0.30 million years ago.[]
S. mansoni and S. rodhaini appear to have shared a common ancestor between 107.5-147.6 thousand years ago.[8] This period overlaps with the earliest archaeological evidence for fishing in Africa. It appears that S. mansoni originated in East Africa and experienced a decline in effective population size 20-90 thousand years ago before dispersing across the continent during the Holocene. This species was later transmitted to the Americas by the slave trade.
S. incognitum and S. nasale are more closely related to the African species rather than the japonicum group.[]
S. sinensium appears to have radiated during the Pliocene.[]
S. mekongi appears to have invaded South East Asia in the mid-Pleistocene.[]
Estimated speciation dates for the japonicum group: ~3.8 million years ago for S. japonicum/South East Asian schistosoma and ~2.5 million years ago for S. malayensis/S. mekongi.[]
Schistosoma turkestanicum is found infecting red deer in Hungary. These strains appear to have diverged from those found in China and Iran.[9] The date of divergence appears to be 270,000 years before present.
The genus Schistosoma as currently[when?] defined is paraphyletic,[] so revisions are likely. Over twenty species are recognised within this genus.
The genus has been divided[] into four groups: indicum, japonicum, haematobium and mansoni. The affinities of the remaining species are still being clarified.
Thirteen species are found in Africa. Twelve of these are divided into two groups -- those with a lateral spine on the egg (mansoni group) and those with a terminal spine (haematobium group).
Mansoni group
The four mansoni group species are: S. edwardiense, S. hippotami, S. mansoni and S. rodhaini.
Haematobium group
The nine haematobium group species are: S. bovis, S. curassoni, S. guineensis, S. haematobium, S. intercalatum, S. kisumuensis, S. leiperi, S. margrebowiei and S. mattheei.
S. leiperi and S. matthei appear to be related.[10]S. margrebowiei is basal in this group.[11]S. guineensis is the sister species to the S. bovis and S. curassoni grouping. S. intercalatum may actually be a species complex of at least two species.[12][13]
Indicum group
The indicum group has three species: S. indicum, S. nasale and S. spindale. This group appears to have evolved during the Pleistocene. All use pulmonate snails as hosts.[]S. spindale is widely distributed in Asia, but is also found in Africa.[] They occur in Asia and India.[]
S. indicum is found in India and Thailand.[]
The indicum group appears to be the sister clade to the African species.[14]
Japonicum group
The japonicum group has three species: S. japonicum, S. malayensis and S. mekongi.[]
S. sinensium is a sister clade to the S. japonicum group and is found in China.[]
S. ovuncatum forms a clade with S. sinensium and is found in northern Thailand. The definitive host is the black rat (Rattus rattus) and the intermediate host is the snail Tricula bollingi. This species is known to use snails of the family Pomatiopsidae as hosts.
S. incognitum appears to be basal in this genus. It may be more closely related to the African-Indian species than to the Southeast Asian group. This species uses pulmonate snails as hosts.[] Examination of the mitochondria suggests that Schistosoma incognitum may be a species complex.[15]
As of 2012, four additional species have been transferred to this genus.,[7] previously classified as species in the genus Orientobilharzia. Orientobilharzia differs from Schistosoma morphologically only on the basis of the number of testes. A review of the morphological and molecular data has shown that the differences between these genera are too small to justify their separation. The four species are
The hybrid S. haematobium-S.guineenis was observed in Cameroon in 1996. S. haematobium could establish itself only after deforestation of the tropical rainforest in Loum next to the endemic S. guineensis; hybridization led to competitive exclusion of S. guineensis.[16]
In 2003, a S. mansoni-S. rodhaini hybrid was found in snails in western Kenya,[17] As of 2009, it had not been found in humans.[18]
In 2009, S. haematobium-S. bovis hybrids were described in northern Senegalese children. The Senegal River Basin had changed very much since the 1980s after the Diama Dam in Senegal and the Manantali Dam in Mali had been built. The Diama dam prevented ocean water to enter and allowed new forms of agriculture. Human migration, increasing number of livestock and sites where human and cattle both contaminate the water facilitated mixing between the different schistosomes in Nder e.g.[18] The same hybrid was identified during the 2015 investigation of a schistosomiasis outbreak on Corsica, traced to the Cavu river.[19]
In 2019, a S. haematobium-S. mansoni hybrid was described in a 14-year-old patient with hematuria from Côte d'Ivoire.[20]
A cladogram based on 18S ribosomal RNA, 28S ribosomal RNA, and partial cytochrome c oxidase subunit I (COI) genes shows phylogenic relations of species in the genus Schistosoma:[21]
Schistosoma sp. from Ceratophallus natalensis
Comparison of eggs
Geographical areas associated with schistosomiasis by the World Health Organization as of January 2017 include in alphabetical order: Africa, Brazil, Cambodia, the Caribbean, China, Corsica, Indonesia, Laos, the Middle East, the Philippines, Suriname, and Venezuela.[22] There had been no cases in Europe since 1965, until an outbreak occurred on Corsica.[19]
The parasitic flatworms of Schistosoma cause a group of chronic infections called schistosomiasis known also as bilharziasis.[23] An anti-schistosome drug is a schistosomicide.
Species infecting humans
Parasitism of humans by Schistosoma appears to have evolved at least three occasions in both Asia and Africa.
S. guineensis, a recently described species, is found in West Africa. Known snail intermediate hosts include Bulinus forskalii.
S. haematobium, commonly referred to as the bladder fluke, originally found in Africa, the Near East, and the Mediterranean basin, was introduced into India during World War II. Freshwater snails of the genus Bulinus are an important intermediate host for this parasite. Among final hosts humans are most important. Other final hosts are rarely baboons and monkeys.[24]
S. intercalatum. The usual final hosts are humans. Other animals can be infected experimentally.[24]
S. japonicum, whose common name is simply blood fluke, is widespread in East Asia and the southwestern Pacific region. In Taiwan this species only affects animals, not humans. Freshwater snails of the genus Oncomelania are an important intermediate host for S. japonicum. Final hosts are humans and other mammals including cats, dogs, goats, horses, pigs, rats and water buffalo.[24]
S. malayensis This species appears to be a rare infection in humans and is considered to be a zoonosis[]. The natural vertebrate host is von Muller's rat (Rattus muelleri). The snail host(s) are Robertsiella species (R. gismanni, R. kaporensis and R. silvicola (see Attwood et al. 2005 Journal of Molluscan Studies Volume 71, Issue 4 pp. 379-391).
S. mansoni, found in Africa, Brazil, Venezuela, Suriname, the lesser Antilles, Puerto Rico, and the Dominican Republic. It is also known as Manson's blood fluke or swamp fever. Freshwater snails of the genus Biomphalaria are an important intermediate host for this trematode. Among final hosts humans are most important. Other final hosts are baboons, rodents and raccoons.[24]
S. mekongi is related to S. japonicum and affects both the superior and inferior mesenteric veins. S. mekongi differs in that it has smaller eggs, a different intermediate host (Neotricula aperta) and longer prepatent period in the mammalian host. Final hosts are humans and dogs.[24] The snail Tricula aperta can also be experimentally infected with this species.[]
Human Schistosomes
First Intermediate Host
Endemic Area
Schistosoma guineensis Bulinus forskalii West Africa
Schistosoma intercalatum Bulinus spp Africa
Schistosoma haematobium Bulinus spp. Africa, Middle East
Schistosoma japonicum Oncomelania spp. China, East Asia, Philippines
Schistosoma malayensis Robertsiella spp. Southeast Asia
Schistosoma mansoni Biomphalaria spp. Africa, South America, Caribbean, Middle East
Schistosoma mekongi Neotricula aperta Southeast Asia
Species infecting other animals
Schistosoma indicum, Schistosoma nasale, Schistosoma spindale,Schistosoma leiperi are all parasites of ruminants.[]
Schistosoma edwardiense and Schistosoma hippopotami are parasites of the hippo.[]
Schistosoma ovuncatum and Schistosoma sinensium are parasites of rodents.[]
Adult schistosomes share all the fundamental features of the digenea. They have a basic bilateral symmetry, oral and ventral suckers, a body covering of a syncytial tegument, a blind-ending digestive system consisting of mouth, esophagus and bifurcated caeca; the area between the tegument and alimentary canal filled with a loose network of mesoderm cells, and an excretory or osmoregulatory system based on flame cells. Adult worms tend to be 10-20 mm (0.39-0.79 in) long and use globins from their hosts' hemoglobin for their own circulatory system.
Unlike most flatworms, schistosomes are gonochoristic. The narrow female can be seen emerging from the thicker male's gynecophoral canal below his ventral sucker.
Unlike other trematodes, the schistosomes are dioecious, i.e., the sexes are separate. The two sexes display a strong degree of sexual dimorphism, and the male is considerably larger than the female. The male surrounds the female and encloses her within his gynacophoric canal for the entire adult lives of the worms. As the male feeds on the host's blood, he passes some of it to the female. The male also passes on chemicals which complete the female's development, whereupon they will reproduce sexually. Although rare, sometimes mated schistosomes will "divorce", wherein the female will leave the male for another male. The exact reason is not understood, although it is thought that females will leave their partners to mate with more genetically distant males. Such a biological mechanism would serve to decrease inbreeding, and may be a factor behind the unusually high genetic diversity of schistosomes.[25]
The genomes of Schistosoma haematobium, S. japonicum and S. mansoni have been reported.[26][27][28][29]
The eggs of these parasites were first seen by Theodor Maximilian Bilharz, a German pathologist working in Egypt in 1851 who found the eggs of Schistosoma haematobium during the course of a post mortem. He wrote two letters to his former teacher von Siebold in May and August 1851 describing his findings. Von Siebold published a paper in 1852 summarizing Bilharz's findings. Bilharz wrote a paper in 1856 describing the worms more fully and he named them Distoma haematobium. Their unusual morphology meant that they could not be comfortably included in Distoma. So in 1856 Meckel von Helmsback created the genus Bilharzia for them. In 1858 David Friedrich Weinland proposed the name Schistosoma (Greek: "split body") after the male worms' morphology. Despite Bilharzia having precedence, the genus name Schistosoma was officially adopted by the International Commission on Zoological Nomenclature. The term Bilharzia to describe infection with these parasites is still in use in medical circles.[]
Bilharz also described Schistosoma mansoni, but this species was redescribed by Louis Westenra Sambon in 1907 at the London School of Tropical Medicine who named it after his teacher Patrick Manson.[]
In 1898, all then known species were placed in a subfamily by Stiles and Hassel. This was elevated to family status by Looss in 1899. Poche in 1907 corrected a grammatical error in the family name. The life cycle was determined by the Brazilian parasitologist Pirajá da Silva (1873-1961) in 1908.[]
In 2009, the genomes of Schistosoma mansoni and Schistosoma japonicum were decoded [26][27] opening the way for new targeted treatments. In particular, the study discovered that the genome of S. mansoni contained 11,809 genes, including many that produce enzymes for breaking down proteins, enabling the parasite to bore through tissue. Also, S. mansoni does not have an enzyme to make certain fats, so it must rely on its host to produce these.[30]
Praziquantel[31]
^ "Schistosomiasis Fact Sheet". World Health Organization. Retrieved 2011.
^ "Schistosomiasis". Centers for Disease Control and Prevention. Retrieved 2011.
^ Morgan JA, DeJong RJ, Kazibwe F, Mkoji GM, Loker ES (August 2003). "A newly-identified lineage of Schistosoma". Int. J. Parasitol. 33 (9): 977-85. doi:10.1016/S0020-7519(03)00132-2. PMID 12906881.
^ Beer SA, Voronin MV, Zazornova OP, Khrisanfova GG, Semenova SK (2010) Phylogenetic relationships among schistosomatidae. Med Parazitol (Mosk) 2010 (2):53-59
^ Wang CR, Li L, Ni HB, et al. (February 2009). "Orientobilharzia turkestanicum is a member of Schistosoma genus based on phylogenetic analysis using ribosomal DNA sequences". Exp. Parasitol. 121 (2): 193-7. doi:10.1016/j.exppara.2008.10.012. PMID 19014940.
^ Wang Y, Wang CR, Zhao GH, Gao JF, Li MW, Zhu XQ (December 2011). "The complete mitochondrial genome of Orientobilharzia turkestanicum supports its affinity with African Schistosoma spp". Infect. Genet. Evol. 11 (8): 1964-70. doi:10.1016/j.meegid.2011.08.030. PMID 21930247.
^ a b Aldhoun JA, Littlewood DT (2012) Orientobilharzia Dutt & Srivastava, 1955 (Trematoda: Schistosomatidae), a junior synonym of Schistosoma Weinland, 1858. Syst Parasitol 82(2):81-8. doi: 10.1007/s11230-012-9349-8
^ Crellen T, Allan F, David S, Durrant C, Huckvale T, Holroyd N, Emery AM, Rollinson D, Aanensen DM, Berriman M, Webster JP, Cotton JA (2016) Whole genome resequencing of the human parasite Schistosoma mansoni reveals population history and effects of selection. Sci Rep 6:20954. doi: 10.1038/srep20954
^ Lawton SP, Majoros G (2013) A foreign invader or a reclusive native? DNA bar coding reveals a distinct European lineage of the zoonotic parasite Schistosoma turkestanicum (syn. Orientobilharzia turkestanicum). Infect Genet Evol 14:186-93. doi: 10.1016/j.meegid.2012.11.013
^ Kaukas A, Dias Neto E, Simpson AJ, Southgate VR, Rollinson D (1994) A phylogenetic analysis of Schistosoma haematobium group species based on randomly amplified polymorphic DNA. Int J Parasitol 24(2):285-290
^ Webster BL, Southgate VR, Littlewood DT (2006) A revision of the interrelationships of Schistosoma including the recently described Schistosoma guineensis. Int J Parasitol 36(8):947-955
^ Kane RA, Southgate VR, Rollinson D, Littlewood DT, Lockyer AE, Pagès JR, Tchuem Tchuentè LA, Jourdane J (2003) A phylogeny based on three mitochondrial genes supports the division of Schistosoma intercalatum into two separate species. Parasitology 127(Pt 2):131-137
^ Pagès JR, Durand P, Southgate VR, Tchuem Tchuenté LA, Jourdane J (2001) Molecular arguments for splitting of Schistosoma intercalatum, into two distinct species. Parasitol Res 87(1):57-62
^ Agatsuma T, Iwagami M, Liu CX, Rajapakse RP, Mondal MM, Kitikoon V, Ambu S, Agatsuma Y, Blair D, Higuchi T (2002) Affinities between Asian non-human Schistosoma species, the S. indicum group, and the African human schistosomes. J Helminthol 76(1):7-19
^ Webster BL, Littlewood DT (2012) Mitochondrial gene order change in Schistosoma (Platyhelminthes: Digenea: Schistosomatidae). Int J Parasitol 42(3):313-321
^ Tchuem Tchuenté LA, Southgate VR, Njiokou F, Njine T, Kouemeni LE, et al. (1997) The evolution of schistosomiasis at Loum, Cameroon: replacement of Schistosoma intercalatum by S. haematobium through introgressive hybridization. Trans R Soc Trop Med Hyg 91: 664-665.DOI 10.1016/S0035-9203(97)90513-7
^ Morgan JAT, DeJong RJ, Lwambo NJS, Mungai BN, Mkoji GM, et al. (2003) First report of a natural hybrid between Schistosoma mansoni and S. rodhaini. Journal of Parasitology 89: 416-418.
^ a b T Huyse, BL Webster, S Geldof, et al. Bidirectional introgressive hybridization between a cattle and human schistosome species. PLoS Pathog, 5 (2009), p. e1000571. DOI 10.1371/journal.ppat.1000571
^ a b Jérôme Boissier; Sébastien Grech-Angelini; Bonnie L Webster; et al. (2016). "Outbreak of urogenital schistosomiasis in Corsica (France): an epidemiological case study". The Lancet Infectious Diseases. 16 (8): 971-979. doi:10.1016/S1473-3099(16)00175-4. PMID 27197551.
^ Depaquit, Jérôme; Akhoundi, Mohammad; Haouchine, Djamel; Mantelet, Stéphane; Izri, Arezki (2019). "No limit in interspecific hybridization in schistosomes: observation from a case report". Parasite. 26: 10. doi:10.1051/parasite/2019010. ISSN 1776-1042. PMC 6396650. PMID 30821247.
^ Brant, S. V.; Morgan, J. A. T.; Mkoji, G. M.; Snyder, S. D.; Rajapakse, R. P. V. J.; Loker, E. S. (2006). "An Approach to Revealing Blood Fluke Life Cycles, Taxonomy, and Diversity: Provision of Key Reference Data Including Dna Sequence from Single Life Cycle Stages". Journal of Parasitology. 92 (1): 77-88. doi:10.1645/GE-3515.1. PMC 2519025. PMID 16629320.
^ WHO factsheet
^ Britannica Concise Encyclopedia 2007
^ a b c d e Manson-Bahr, P.E.C.; Bell, D.R., eds. (1987). Manson's Tropical Diseases. London: Bailliere Tindall. ISBN 978-0-7020-1187-0.
^ "Even Blood Flukes Get Divorced - The Loom". The Loom. 2008-10-08. Retrieved .
^ a b Zhou, Y.; Zheng, H.; Chen, Y.; Zhang, L.; Wang, K.; Guo, J.; Huang, Z.; Zhang, B.; Huang, W.; Jin, K.; Dou, T.; Hasegawa, M.; Wang, L.; Zhang, Y.; Zhou, J.; Tao, L.; Cao, Z.; Li, Y.; Vinar, T.; Brejova, B.; Brown, D.; Li, M.; Miller, D. J.; Blair, D.; Zhong, Y.; Chen, Z.; Liu, F.; Hu, W.; Wang, Z. Q.; Zhang, Q. H. (2009). "The Schistosoma japonicum genome reveals features of host-parasite interplay". Nature. 460 (7253): 345-351. Bibcode:2009Natur.460..345Z. doi:10.1038/nature08140. PMC 3747554. PMID 19606140.
^ a b Berriman, M.; Haas, B. J.; Loverde, P. T.; Wilson, R. A.; Dillon, G. P.; Cerqueira, G. C.; Mashiyama, S. T.; Al-Lazikani, B.; Andrade, L. F.; Ashton, P. D.; Aslett, M. A.; Bartholomeu, D. C.; Blandin, G.; Caffrey, C. R.; Coghlan, A.; Coulson, R.; Day, T. A.; Delcher, A.; Demarco, R.; Djikeng, A.; Eyre, T.; Gamble, J. A.; Ghedin, E.; Gu, Y.; Hertz-Fowler, C.; Hirai, H.; Hirai, Y.; Houston, R.; Ivens, A.; Johnston, D. A. (2009). "The genome of the blood fluke Schistosoma mansoni". Nature. 460 (7253): 352-358. Bibcode:2009Natur.460..352B. doi:10.1038/nature08160. PMC 2756445. PMID 19606141.
^ Young, N. D.; Jex, A. R.; Li, B.; Liu, S.; Yang, L.; Xiong, Z.; Li, Y.; Cantacessi, C.; Hall, R. S.; Xu, X.; Chen, F.; Wu, X.; Zerlotini, A.; Oliveira, G.; Hofmann, A.; Zhang, G.; Fang, X.; Kang, Y.; Campbell, B. E.; Loukas, A.; Ranganathan, S.; Rollinson, D.; Rinaldi, G.; Brindley, P. J.; Yang, H.; Wang, J.; Wang, J.; Gasser, R. B. (2012). "Whole-genome sequence of Schistosoma haematobium" (PDF). Nature Genetics. 44 (2): 221-225. doi:10.1038/ng.1065. PMID 22246508.
^ Protasio, A. V.; Tsai, I. J.; Babbage, A.; Nichol, S.; Hunt, M.; Aslett, M. A.; De Silva, N.; Velarde, G. S.; Anderson, T. J. C.; Clark, R. C.; Davidson, C.; Dillon, G. P.; Holroyd, N. E.; Loverde, P. T.; Lloyd, C.; McQuillan, J.; Oliveira, G.; Otto, T. D.; Parker-Manuel, S. J.; Quail, M. A.; Wilson, R. A.; Zerlotini, A.; Dunne, D. W.; Berriman, M. (2012). Hoffmann, Karl F (ed.). "A Systematically Improved High Quality Genome and Transcriptome of the Human Blood Fluke Schistosoma mansoni". PLoS Neglected Tropical Diseases. 6 (1): e1455. doi:10.1371/journal.pntd.0001455. PMC 3254664. PMID 22253936.
^ "Killer parasites' genes decoded". BBC News. July 16, 2009. Retrieved .
^ https://www.cdc.gov/parasites/schistosomiasis/health_professionals/
British Department for International Development Control of Schistosomiasis
The World Health Organisation page on Schistosomiasis
University of Cambridge Schistosome Laboratory
Schistosoma parasites overview, biology, life cycle image at MetaPathogen
Ross, A. G. P.; Sleigh, A. C.; Li, Y.; Davis, G. M.; Williams, G. M.; Jiang, Z.; Feng, Z.; McManus, D. P. (2001). "Schistosomiasis in the People's Republic of China: Prospects and Challenges for the 21st Century". Clinical Microbiology Reviews. 14 (2): 270-295. doi:10.1128/CMR.14.2.270-295.2001. PMC 88974. PMID 11292639.
Schistosoma mansoni pair
Schistosoma ELISA kit
[PDF] FREE Schistosoma: Biology, Pathology and Control [Download] Online
Cycle Schistosoma
Schistosoma miricidium (larva)
Download Schistosoma Mansoni: Parasite Surface in Relation to Host Immunity PDF Full Ebook
Schistosoma haematobium Miracidium Swimming Inside Egg
Schistosoma Mansoni Cercariae
E.Histolytica ELISA kit
DENGUE-IgG ELISA kit
DENGUE-IgM ELISA kit
Leishmania ELISA kit
Tetanus-ELISA-kit
Chagas ELISA kit
DENGUE IgG-IgM ELISA kit
Diptheria ELISA kit
Parasitos en el cerebro: Esquistosoma Mansoni
Strongyloides ELISA kit


Training, guidance and black belts, it's all in a day's work.
Francisco Dominguez tells us about his day working as Director of Quality at CMP Products and the impact of his role on the company.
Throughout July, British Engines welcomed 80 university students from Singapore, to our BEL Valves and BEL Engineering sites, in collaboration with Newcastle University.


text:
Kane family collection
Identifier: MSS 3190
Overview The Thomas L. and Elizabeth W. Kane family collection, 1835-1931, contains a series of materials relating primarily to Thomas, Elizabeth, and three of their four children: Harriet Amelia Kane, Elisha Kent Kane, and Evan O'Neill Kane. Among these is an American Civil War pocketbook kept by Thomas L. Kane; an original patriarchal blessing given to Thomas at Council Bluffs by Mormon patriarch John Smith and recorded by Wilford Woodruff; a letter sent from Brigham Young to Thomas when the latter...
Dates: approximately 1835-1931
Found in: L. Tom Perry Special Collections / Kane family collection
Kane family encased photographs, approximately 1845-1865
Identifier: Vault MSS 792 Series 12 Sub-Series 4 Sub-Series 3
Scope and Contents Contains encased photographs, including ambrotypes and tintypes, collected by the Kane family. Most of the images are not identified. Materials date from between about 1845 and 1865.
Found in: L. Tom Perry Special Collections / Vault MSS 792, Kane family papers / Kane family photographs / Kane family photographs of other subjects
Kane family notes, cards, and other material, 1849-1866
Series — Multiple Containers
Identifier: MSS 3190 Series 8
Scope and Contents Contains a letter, several notes, picture cards, and a botanical pressing found within printed works in the Kane family collection. The letter is concerns a trial and injustice in the life of Thomas L. Kane and is signed by his aunt. The notes include copied scriptural and lyrical passages, as well as notes on a book concerning genealogy. The picture cards depict religious scenes. Materials date from 1849 to the late 19th century.
Dates: Other: 1849-1866
Found in: L. Tom Perry Special Collections / MSS 3190, Kane family collection
Kane family oversized photographs, approximately 1840-1900
Scope and Contents Contains oversized photographs of or related to the Kane family. The photographs depict people and portraits of people, a house that presumably was occupied by the Kane family, a monument dedicated to Thomas L. Kane's Civil War regiment "The Bucktails," and a reunion of that regiment. Materials are largely undated and unlabeled, but presumably date from the mid-19th century to early 20th century.
Found in: L. Tom Perry Special Collections / MSS 3190, Kane family collection / Kane family photographs
Kane family papers
Identifier: Vault MSS 792
Scope and Contents Materials contain the papers of the Kane family of Philadelphia and Kane, Pennsylvania. Includes papers created and collected by John K. Kane and his wife, Jane Duval Kane; and their children, specifically Thomas L. Kane and his wife, Elizabeth Kane. Contains letters to and from several important American political and historical figures, including Alexander Hamilton, Aaron Burr, John Hancock, Andrew Jackson, Horace Greeley, and U.S. Grant. A large portion of the collection also deals with...
Found in: L. Tom Perry Special Collections / Kane family papers
Kane family photograph album, approximately 1840-1900
Scope and Contents Contains photographs found in first volume the Kane family photograph album. The photographs primarily depict places in the United Kingdom such as Oxford, Cambridge, and King's College, but also depict scenes in the United States and Canada, including the town of Kane, Pennsylvania, New York, Washington D.C., and Niagara Falls. Materials are largely undated and unlabeled, but presumably date from the mid 19th century to early 20th century.
Scope and Contents Contains photographs found in the second volume of the Kane family photograph album. The photographs depict people and portraits of people known to the Kane family. These include Elizabeth Wood Kane's father, William Wood, and many unnamed people who are presumably Kane or Wood family members, and a single photograph depicting a living room. Materials are largely undated and unlabeled, but presumably date from the mid-19th century to early 20th century.
Scope and Contents Contains photographs found in the third volume of the Kane family photograph album. The photographs primarily depict people known to the Kane family. These include photographs of the deceased Thomas L. Kane, and many unnamed people who are presumably Kane or Wood family members. Materials are largely undated and unlabeled, but presumably date from the mid-19th century to early 20th century.
Kane family photographs
Identifier: MSS P 426
Scope and Contents Contains photographs of the Kane family, as well as images of monuments and buildings related to the family members and their activities. Also includes numerous photographs of E. Kent Kane's visit to Utah and tour of the state with Heber J. Grant.
Found in: L. Tom Perry Special Collections / Kane family photographs
Kane family photographs, approximately 1840-1900
Scope and Contents Contains photographs and related materials by or of the Kane family. The photographs depict a wide variety of people and places, including Kane family members, the town of Kane, Pennsylvania, England and Scotland, and Thomas L. Kane's Civil War regiment "The Bucktails." Also included are the original steel plate of a portrait of Thomas L. Kane, and five printings from that plate. Materials are largely undated and unlabeled, but presumably date from the mid-19th century to early 20th century.
Dates: Other: approximately 1840-1900
Names: Kane (Family : Kane, Thomas L. (Thomas Leiper), 1822-1883) X
Archival Record 24
Cain family 26
Kane, Thomas L. (Thomas Leiper), 1822-1883 5
United States. Army. Pennsylvania Infantry Regiment, 42nd (1861-1864) 3
Wood family 3
Cannon, George Q. (George Quayle), 1827-1901 1
Church of Jesus Christ of Latter-day Saints 1
Grant, Heber J. (Heber Jeddy), 1856-1945 1
Kane, E. Kent (Elisha Kent), 1902-1980 1
Kane, John K. (John Kintzing), 1795-1858 1
Utah Expedition (1857-1858) 1
Wood, William, 1808-1894 1


Discussion in 'Home Networking' started by Paul G, Mar 25, 2014.
1. How stable is DD-WRT with VPN ? I'm running V24-sp2 ..
replace my existing router so a VPN server would simply sit in the DMZ.
suitable for this or do I need a proxy too ?