text:
Protalix Presents Additional Phase III Data For Taliglucerase Alfa At The WORLD Symposium
Published	 Friday 12 February 2010	 Published	Fri 12 Feb 2010
Protalix BioTherapeutics, Inc. (NYSE-Amex: PLX), announced that additional data from the Company's pivotal Phase III clinical trial of taliglucerase alfa in patients with Gaucher disease was presented at the Annual Meeting of the Lysosomal Disease Network: WORLD Symposium 2010 in Miami, Florida, during an oral session titled, "Novel Enzyme Replacement Therapy for Gaucher Disease: Phase III Pivotal Clinical Trial with Plant Cell Expressed Recombinant Glucocerebrosidase (prGCD) - taliglucerase alfa." The oral presentation was made by Hanna Rosenbaum M.D., Director of Hematology Day Care Unit, RAMBAM Medical Center, Haifa, Israel, and study investigator.
"I believe the data from the Phase III trial demonstrates that taliglucerase alfa is well tolerated and clinically effective in treating Gaucher disease," said Dr. Hanna Rosenbaum.
The pivotal Phase III clinical trial was a multi-center, world-wide, randomized, double-blind, parallel group, dose-ranging study to assess the safety and efficacy of taliglucerase alfa in 31 treatment-naive patients suffering from Gaucher disease. In the trial, patients were selected randomly for one of two dosing arms (60 U/kg or 30 U/kg) and received intravenous infusions of taliglucerase alfa once every two weeks for a nine month period. The primary endpoint of the study was a 20% mean reduction from baseline in spleen volume after nine months, as measured by MRI. Major secondary endpoints were an increase in hemoglobin, decrease in liver volume and increase in platelet count. The trial enrolled patients at 11 centers throughout Europe, Israel, North America, South America and South Africa.
Taliglucerase alfa significantly reduced mean spleen volume after nine months compared with baseline in both treatment groups. The 60 U/kg group demonstrated a statistically significant mean reduction in spleen volume of 38.0% (p
Statistically significant improvements were also observed for the secondary endpoints after nine months when compared to baseline for the 60 U/kg dose. Patients demonstrated a mean increase in hemoglobin of 2.2 g/dL or 22.2% (p
Thirty patients in the trial had Chitotriosidase measurements, a biomarker for clinical symptoms of Gaucher disease. In these patients, Chitotriosidase decreased from baseline in both the 30U/kg and 60U/kg groups by 47.3% and 58.4% respectively.
The safety analysis for both treatment groups showed that taliglucerase alfa was well tolerated and no serious or severe adverse events were reported. Two patients in the trial developed antibodies to taliglucerase alfa and no patients developed neutralizing antibodies. In addition, two patients experienced hypersensitivity reactions to taliglucerase alfa. No anti-taliglucerase antibodies were detected in these patients and both reactions were treated in the physicians' clinic and reversed.
Most adverse events were considered unrelated to taliglucerase alfa. The most frequent mild to moderate adverse event was headache. Other mild to moderate adverse events included dizziness, muscle spasm, chest discomfort, nausea, skin irritation and arthalgia.
"The Phase III results reported today not only support the use of taliglucerase alfa for the treatment of Gaucher disease, but also support the Company's plant cell based platform technology," said Dr. David Aviezer, President and CEO of Protalix. "Patients who successfully completed this pivotal study have continued to receive taliglucerase alfa as part of our ongoing extension trial, some for over two and a half years."
The Company is currently conducting a world-wide switch over study investigating the efficacy and safety of switching to taliglucerase alfa from the currently approved enzyme replacement therapy. In addition, taliglucerase alfa is being provided to patients in the United States under an Expanded Access protocol and to patients in the European Union, Israel and other countries under Named Patient provisions.
About Gaucher disease
Gaucher disease, an inherited condition, is the most prevalent lysosomal storage disorder, with an incidence of about one in 20,000 live births. People with Gaucher disease do not have enough of an enzyme, beta-glucosidase (glucocerebrosidase) that breaks down a certain type of fat molecule. As a result, lipid engorged cells (called Gaucher cells) amass in different parts of the body, primarily the spleen, liver and bone marrow. Accumulation of Gaucher cells may cause spleen and liver enlargement, anemia, excessive bleeding and bruising, bone disease and a number of other signs and symptoms.
About Protalix
Protalix is a biopharmaceutical company focused on the development and commercialization of proprietary recombinant therapeutic proteins expressed through its proprietary plant cell based expression system. Protalix's ProCellEx(TM) presents a proprietary method for the expression of recombinant proteins that Protalix believes will allow for the industrial-scale production of recombinant therapeutic proteins in an environment free of mammalian components and viruses. Protalix is also advancing additional recombinant biopharmaceutical drug development programs. Taliglucerase alfa is an enzyme replacement therapy in development under a Special Protocol Assessment with the FDA for Gaucher disease. In August 2009, the FDA granted orphan drug status and fast track designation to taliglucerase alfa for the treatment of Gaucher disease and Protalix filed a rolling NDA submission with the FDA in December 2009. In November 2009, Protalix granted Pfizer Inc. exclusive, worldwide rights to develop and commercialize taliglucerase alfa for the treatment of Gaucher disease, except in Israel. Protalix retained the right to commercialize taliglucerase alfa in Israel.
Safe Harbor Statement:
To the extent that statements in this press release are not strictly historical, all such statements are forward-looking, and are made pursuant to the safe-harbor provisions of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are subject to known and unknown risks and uncertainties that may cause actual future experience and results to differ materially from the statements made. These statements are based on our current beliefs and expectations as to such future outcomes. Drug discovery and development involve a high degree of risk. Factors that might cause material differences include, among others, risks relating to: the successful preclinical development of our product candidates; the completion of clinical trials; the review process of the FDA, the EMEA, other foreign regulatory bodies and other governmental regulatory bodies, including the FDA's and the EMEA's review of any filings we make in connection with the treatment protocol; delays in the FDA's, the EMEA's or other health regulatory authorities' approval of any applications we file or refusals to approve such filings; refusals by such regulatory authorities to approve the marketing and sale of a drug product even after acceptance of an application we file for any such drug product; the identification of lead compounds; the risk that we may fail to satisfy certain conditions relating to grants we have received from the Office of the Chief Scientist of Israel's Ministry of Industry and Trade which may lead to our being required to refund grants previously received together with interest and penalties; the risk that the Office of the Chief Scientist may not deliver to us all of the funds awarded to us; uncertainties related to the ability to attract and retain partners for our technologies and products under development; and other factors described in our filings with the Securities and Exchange Commission. Companies in the pharmaceutical and biotechnology industries have suffered significant setbacks in advanced or late-stage clinical trials, even after obtaining promising earlier trial results or in preliminary findings for such clinical trials. Further, even if favorable testing data is generated by clinical trials of drug products, the FDA, EMEA or any other foreign regulatory authority may not accept or approve an NDA filed by a pharmaceutical or biotechnology company for such drug product. Failure to obtain approval from the FDA, EMEA or any other foreign regulatory authority of any of our drug candidates in a timely manner, if at all, will severely undermine our business and results of operation by reducing our potential marketable products and our ability to generate corresponding product revenues. The statements in this release are valid only as of the date hereof and we disclaim any obligation to update this information.
Source: Protalix BioTherapeutics, Inc
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BioTherapeutics, Protalix. "Protalix Presents Additional Phase III Data For Taliglucerase Alfa At The WORLD Symposium." Medical News Today. MediLexicon, Intl., 12 Feb. 2010. Web.
BioTherapeutics, P. (2010, February 12). "Protalix Presents Additional Phase III Data For Taliglucerase Alfa At The WORLD Symposium." Medical News Today. Retrieved from
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This month we launched the Bureau Hub, our Gallery, CPD and Seminar Facility at Speirs Wharf, Glasgow.
Bureau Hub provides a space where workspace and leisure brands can showcase their collections to the architecture and design community of Scotland. A rotating, collaborative space, exhibitions will change periodically, and a programme of CPDs will run throughout the year.
On the ground floor our seminar space will host CPDs and 'lunch and learn' events. There are some really interesting subjects in the pipeline, so keep your eyes peeled for our upcoming events.
We're hosting a number of exhibitors throughout the year who will occupy the Foyer and Gallery spaces, where collections can be viewed in a relaxed and informal environment, with a well stocked bar!
Our programme for the year kicked off with guests exhibitors, The Collective Agency, bringing modular furniture from Ophelis and Norwegian designs from Eikund.
The collections will remain in the Hub until the end of March and we welcome visitors to view the collections or bring clients and arrange your meetings here.
Meetings can be convened in our luxurious Leisure Suite or Boardroom. Feel free to make use of these facilities. Please get in touch if you would like to reserve any of our spaces.
If you would like to visit, exhibit with us or use our Glasgow based seminar and meeting facilities, please get in touch with Mac, our Showroom and Events Manager - events@yourbureau.com.


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Q: Using CATransformLayer warning: changing property opaque in transform-only layer, will have no effect I created a "TransformView" subclassing UIView in order to support a double-sided view which I am using in a flip animation. This has been suggested in other posts, eg:
How to rotate a flat object around its center in perspective view?
@interface TransformView : UIView
@end

@implementation TransformView
+ (Class)layerClass {
  return [CATransformLayer class];
}
@end

It all works fine, but I get a warning every time I create a TransformView object using:
TransformView *newTransformView=[[TransformView alloc] initWithFrame:frame];

The warning says:

 - changing property opaque in
  transform-only layer, will have no effect

I guess the UIView class is initialising the opaque property which is usually fine for a CALayer but not a CATransformLayer.
Is the subclassing code quite dodgy? If so, how else can you create a 2-sided view for flip animations?
Any ideas for how to stop the warning?
I have a suspicion that creating a TransformView from a nib file rather than initWithFrame avoids the warning, but is seem cludgy to have to do this just to avoid the warning.

A: Your can avoid the warning by adding this extension somewhere in your code:
@implementation CATransformLayer (MyExtension)
-(void)setOpaque:(BOOL)opaque
{
    return;
}
@end

Of course this will also stop the warning for your own mistaken attempts to set the opaque property of a CATransformLayer.

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Sports News Tips Sportsbook Reviews Promo Codes Sportsbook Apps Premier League Matches Football Teams Competitions Players
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matches played 256
Last appearance (days ago) 4
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Height (cm) 177
Dagenham & Redbridge FC
Dwight Gayle is currently fourth in Championship (United Kingdom) with his team West Bromwich Albion. In terms of preferred feet, Dwight Gayle is a right footer, like 63% of West Bromwich Albion. Born on October 17, 1990, his age of 28 underlies his team's mean. Back in 2018, English forward Dwight Gayle's contract with West Bromwich Albion (United Kingdom), the club he is still a member of, took effect. Standing 1.77 meter high, he is tinier, when looking at the average height in his team.
He already played 41 matches this season. Dwight Gayle also plays for Newcastle United. His shortest spell with a club was just two months in Peterborough United (United Kingdom). In terms of top seasons, the Championship 18/19 (United Kingdom) was his best one yet, breaking two personal records in terms of not only goals but also appearances. Already 18 times a card was given to Dwight Gayle in his tenure. This season he scored 24 and assisted no goals which is 27.6% of all of West Bromwich Albion's goals in Championship 18/19 (United Kingdom). On average, he hit the net 0.59 times per match this season which is a better performance than last year's. Back then 0.16 goals and 0.08 assists per match have been achieved.
Throughout his professional career, he participated in 228 games, the last appearance being three days ago. Dwight Gayle plays with the jersey number 16. While being substituted more out than in this season, we can observe that this trend came from last season. Moreover, he shows 69 out and 68 in substitutions in total. Prior to joining West Bromwich Albion, he played for Crystal Palace, Dagenham & Redbridge FC, Peterborough United and Bishop's Stortford. The longest period that Dwight Gayle stayed in a team was two years and 11 months in Crystal Palace (United Kingdom)
Concerning the latest matches, his club won in Championship. He weighs 73kg which is 3kg less than his team's average heftiness. West Bromwich Albion has eight more forwards in their squad, namely Hal Robson-Kanu, Rakeem Harper, Jefferson Montero, Morgan Rogers, Rayhaan Tulloch, Jonathan Leko, Matt Phillips and Jay Rodriguez. Ever since Dwight Gayle became a professional, he has been committed to overall six clubs.
(Last edited May 14, 2019)

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text:
What We Carried
Many Roads to Here
There Is a Land Over the Ocean
I Am My Story
To Bear Witness:
AsyleeBurmaGenocideImmigrantRohingyaStory
Once Home, Now a Jungle
Posted September 20, 2019 November 26, 2019 Allison Merkel
Sankar Raman / The Immigrant Story
For the first 18 years of his life, Reza Uddin was a citizen of Burma, now officially known as Myanmar. And then, suddenly, he was not. That's because Uddin is Rohingya, and in 1982, the Burmese government began denying citizenship to its Rohingya population.
Uddin was born in 1964 to a prominent family in a township in the Rakhine state called Maungdaw. His father, an English teacher, had worked as an interpreter for the British during World War II. His family owned a pharmacy in town, as well as farmland in the country. Like most Rohingya in Maungdaw, Uddin's Muslim family lived side-by-side with Buddhists. "The neighborhood that I grew up in is a combination of the Rohingya Muslims and Rakhine Buddhists, so we were kind of mixed. We had a lot of friends– Bhurmese friends, Buddhist friends, Rohingya friends," he remembers.
It wasn't until Uddin applied to college that he began to feel the effects of the Citizenship Law. Buddhists were automatically granted the required National Registration Cards, but he had to use personal connections and a bribe to get a card.
While Uddin was in college, the government started taking land from the Rohingya in his hometown and redistributing it to Buddhists. Active in student movements for Rohingya rights, Uddin avoided visiting his home village. The one time he did return there, a special unit of the police interrogated him and instructed him to report to them everyday. At the end of the trip, his father advised him to start looking for opportunities in other countries and instructed him never to come back home.
Uddin followed both pieces of his father's advice: He applied for a student visa in the United States, and would never again see his hometown. In 1993, he moved to Pendleton, Ore., where his brother was working as a plant pathologist, and enrolled at Blue Mountain Community College. A year after his arrival, his brother accepted a job at the University of Georgia, leaving Uddin to fend for himself.
With no means of transportation, he walked to class everyday and the town took notice. "There was a whole front page article on me. Asking where I was from, how I ended up here… it was very curious for them," he explains. After the article was published, local librarians started showing up at his house to give him a ride.
When Uddin's visa expired, one of the librarians from his college in Pendleton drove him to Portland to speak with an immigration lawyer. Later, he was told that the librarian had paid the retainer fee: "I saw he had already written the check for me for $1,500. He never told me," says Uddin. Only ten days after submitting his application, he was granted asylum.
Uddin transferred to Portland State University in 1995, and graduated with a degree in chemistry. While at PSU, he was hired as a lab technician for an environmental company in Portland, where he worked for ten years. Today, he lives in West Linn with his two daughters and his wife, who is also from Myanmar. The couple run a gas station in Salem. In 2017, Uddin founded Friends of the Rohingya, an organization that helps support Rohingya refugees. Within the first year, the group raised more than $140,000.
Although Uddin has never returned to his hometown, he has been back to Myanmar a handful of times: he returned to the capital city of Yangon (formerly known as Rangoon) for his wedding in 2002, a ceremony his family wasn't allowed to attend, and has visited the refugee camps in Bangladesh that house hundreds of thousands of Rohingya refugees.
As for his hometown: Maungdaw Township bore the brunt of much of the violence launched by Myanmar government forces against the Rohingya community in the Rakhine state. In just one month, beginning Aug. 25, 2017, United Nations figures show that 288 villages were partially or entirely destroyed, their residents killed or forced to flee to neighboring Bangladesh. Calling the plight of the Rohingya the world's fastest growing refugee crisis, the U.N. has labeled the government action against the Rohingya "a textbook example of ethnic cleansing."
"All the villages that people left, some of them are already bulldozed and wiped out, or they are growing, and animals from the jungle, like tigers and snakes, are there," Uddin said. "The houses are all razed down to the ground."
Without overwhelming international support, nothing will change in Myanmar, according to Uddin. Through his activism, he tries to spread awareness: "We have to keep the spotlight on this tragic situation," he says, "Otherwise it will fade out."
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One thought on "Once Home, Now a Jungle"
Abumahiya says:
very interesting long journey history i think every Rohingya who are over overseas has the same or similar travel stories of history
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text:
Hansell, Harry Ernest Letter: 1944 July 24th
Date: July 24th 1944
Charles P. Gower
Minister of National Defense for Air
Ottawa, July 24th, 1944.
Ernest J. Hansell, Esq., M..P.
Ottawa, Canada.
In answer to your letter of June 20th, I am now in receipt
of a reply from Air Marshall Breadner, Air Officer Commanding-in-Chief, Overseas,
copy of which I enclose for your information.
"Charles G. Power"
HEADQUARTERS OF THE
AIR OFFICER COMMANDING-IN-CHIEF
RCAF OVERSEAS
By Bomber Mail;
20 Lincoln's Inn Fields,
London W.C.2.
My Dear Minister,
I have your letter of the twenty third of June with which you enclosed a copy of a letter you received from Mr. Ernest G. Hansell, M.P. concerning the activities of his son during his period of duty in England.
Attached is an appendix which gives as complete an answer to each of the questions .… puts in his letter to you as it is possible to give in the circumstances. In giving the particulars of targets and dates in answer to his second question I need hardly state that they are for Mr. ....... information only and are not for publication.
L.S. Breadner, A.M.
Major, the Honourable C.G. Power, M.C.,
Minister of National Defence for Air,
OTTAWA..
APPENDIX TO A.O.C.-in-C's LETTER TO THE MINISTER
OF 14.7.44
QUESTION 1 -
FS ….. disembarked in the U.K. on March 11th, 1943 and proceeded immediately to the R.C.A.F. Personnel Reception Centre, where he remained until March 30th, on which date he was posted to an operational Training Unit. It is the usual procedure for crews to be formed at Operational Training Units, with the exception of Flight Engineers, who are allotted to their respective crews at Conversion Units and while there is no definite reference in the records of this unit that the crew of which …. was a member was made up here, subsequent records rather confirm that this was the case, and it is therefore assumed that ..... was with the same crew throughout his training as well as his operational career. FS ….. was on the strength of this Operational Training Unit until May l8th, 1945, when he was posted to a Conversion Unit in the R.C.A.F. Bomber Group. Conversion training completed, the crew reported to No.427 Squadron on May 28th 1943 but did not carry out any operations with this Squadron, although the pilot acted as second pilot of an aircraft on June 11th, 1943 in an attack on Dusseldorf, to gain operational experience. On June 15th, this crew and several others were posted to No.434 Squadron, then in process of formation, to form a nucleus of trained crews for this new Halifax Squadron.
The particu1ars of the air operational flights made by this crew are as follows:
Bombing attack on Leverkusen, Aircraft was air borne at 2115 hours but was forced to return early, due to technical failure, without having bombed the target.
Bombing attack on Berlin. Aircraft airborne at 2040 hours but was forced to return early due to technical failure, without having bombed target.
29.8.43.
Bombing attack Nurnberg. Successfully bombed the target, the crew reporting that they saw several bomb bursts and a very good concentration of fires in the target area.
Bombing attack Montlucon. Successfully bombed the target, crew reporting that a large column of smoke was rising and fires were commencing in the target area.
Bombing attack Hanover. Successfully bombed the target, crew reporting that they saw concentrated fires end clouds of black smoke in the target area, and that the glow of fires could be seen almost as far away as the Dutch coast.
Bombing attack Hanover. 13 aircraft were detailed and 10 of them reported a successful attack. Three aircraft, Including FS ....... failed to return, nothing having been heard of them since take off. On this particular sortie, in addition to the regular seven crew members, a pilot under training from another R.C.A.F. squadron acted as second pilot, which accounts for the crew of eight referred to in P.4 CAs. (Can.) memorandum Can.R.160789#P.4#Cas dated 4th July, 1944.
As stated under question 1, crews are generally formed at operational Training Units, and the flights made by FS ...... would, in all probability, be identical with those made by the rest of the crew.
As nothing was heard of this aircraft - Halifax "X" LK 917 - after take off, it is not possible to advise where it came down. Unfortunately, no burial particulars have been received at this H. Q. up to the present time.


Know What Ben? It's Time For You To Shut Up.
Ben Carson isn't the first physician to run for President and, in fact, isn't the only doctor trying to get into the White House in 2016. He may be the only board-certified doctor, because it's not clear whether Rand Paul is certified or not. Carson certainly is. All the more reason that when he says something which violates the Hippocratic Oath we should ask whether he has the credentials even to claim that he's a bone-fide physician, never mind credentials to be the next President of the United States.
Let me make one thing clear about the Hippocratic Oath. It's not mandatory either to subscribe to it or to follow it. There are some medical schools that don't, in fact, administer the oath to new graduates, there are also various versions of the oath floating around. But the Hippocratic Oath is a reminder that medicine is a profession whose effective practice requires attention not just to science and learning, but to compassion and ethics as well. After all, we vest the responsibility and often the authority for making life and death decisions within the medical profession. So it's heartening to know that this profession expects its members to think and behave according to certain basic and well-tested rules.
And rule number one is: Do No Harm. Now these words aren't, in fact, found in the text of the oath itself. But ask any physician to tell you what it means to subscribe to the Hippocratic Oath and he or she will state either those exact words or words to that effect. Which brings us to the recent statements made by Ben Carson following the slaughter at Umpqua Community College that produced a sickening amount of harm.
The first statement was on Ben's Facebook page, although he scrubbed it when the responses began pouring in. Nevertheless, here's the exact quote: "I never saw a body with bullet holes that was more devastating than taking the right to arm ourselves away." In other words, if Carson was practicing in a locality that had very strict gun-control laws like, for example, Washington, D.C., he would claim that the inability of a D.C. resident to carry around a handgun was a greater medical risk than if that same individual was brought into the ER with a bullet lodged in his head. So much for Carson's ability to stratify gun violence risk, adopt the proper medical response and thereby reduce harm.
Just to make sure that ol' Ben keeps his bone fides alive with the pro-gun crowd, he then went on CBS and said that if he were facing a mass shooter, the first thing he would do is put up a fight. He would also advise other people in the vicinity to do the same thing. Of course macho man Carson has absolutely no idea of the degree to which such behavior increases risk, and if you don't believe me, just take a look at the active shooter guidelines issued by the Department of Homeland Security: Run, hide, if all else fails, fight.
I think it's now time for the medical community to tell their colleague Ben Carson that he should stop putting the initials 'M.D' after his name. Because no doctor who takes his work seriously would make statements like that. Ben doesn't just offend the Umpqua survivors, he offends the profession which he claims to represent. Shut up Ben, just shut the f***up.
Doctors for Responsible Gun Ownership Are Actually Totally Irresponsible.
Sooner or later I knew that Tim Wheeler, who runs a blog called Doctors for Responsible Gun Ownership, would come out and say something that reveals how far away he is from thinking like a serious physician. Or thinking like any kind of physician, for that matter. Since he started his so-called organization, which is basically just a blog, he has spent his time promoting one stupid and/or senseless notion for the gun industry after another stupid and/or senseless notion. From denying that physicians should question patients about guns, to advocating that physicians should hand out gun safety information that has never been reviewed by the medical academies, Wheeler pushes out opinions that pander to the lowest common mental denominator and misrepresent the role of doctors in dealing with health issues, guns or no guns.
Wheeler has now trained his sights on a situation in New Jersey where the legislature is thinking of amending a 'smart gun' law that was passed in 2002 but has never been implemented because no manufacturer could deliver a smart-gun product that both worked and was made available for retail sale. A brief attempt was made to sell one of these models in California, but the gun shop in question quickly removed the produce from its shelves when local gun nuts threatened a boycott of the store or worse.
Wheeler refers to smart-gun technology as a "sweeping infringement" of the 2nd Amendment, a judgement obviously based on his expertise on the area of Constitutional law. If he would bother to actually read the 2008 Heller decision, he might notice that Scalia explicitly states that "nothing in our opinion should be taken to cast doubt on … laws imposing conditions and qualifications on the commercial sale of arms." [p. 54] Notice the phrase, 'commercial sale of arms,' which even a jerk like Wheeler must know means that the government can decide what types of guns can and cannot be sold.
Smart guns were first hyped during the Clinton administration when the government awarded R&D grants to various inventors and entrepreneurs to develop new gun-safety technologies. You can get a very complete overview of the history and development of smart-gun products by reading a report published by the Department of Justice in 2013. The report brought together representatives of federal agencies and test labs, law enforcement bodies, technology institutes, public health researchers, and was discussed with staff from Smith & Wesson, Colt, FN and Ruger, among others.
If Wheeler read the report, perhaps he would have noticed right up front that the primary group of users for whom such technology is being developed is "people responsible for public safety (i.e., law enforcement personnel.)" [P. 8] I think that Wheeler only blogs about issues, like Heller, for which he hasn't read the relevant texts, but why should a physician depend on anything other than his own opinions, correct?
Wheeler not only believes that smart-gun technology represents an 'infringement' on the 2nd Amendment, but worse, is a solution in search of a non-existent problem; i.e., accidental deaths of children from firearm misuse. He refers to these deaths as "miniscule," claiming a "few dozen" lives each year. In fact, more than 75 children under the age of 18 died from accidental shootings in 2013, and more than 560 were treated for gunshot wounds.
But worse than understating the numbers is what this says about Wheler's approach to medicine. Let me break the news to him gently: physicians don't define a medical problem by how many patients present a particular symptom during an exam. The role of the physician, according to the Hippocratic Oath, is to reduce harm. And this applies to every single patient, whether the harm comes from something which is nearly universal, or is something that a physician might see only once.
Wheeler's attempt to make readers believe that the severity of a problem is in any way based on its frequency is a conscious misstatement of the role of the physician and shows him to be the crackpot and gun industry mouthpiece that he really is.
Physicians And Guns: Another NRA Sycophant Ignores The Truth.
As physicians slowly but surely push their way back into the debate about gun violence, you can be sure that the NRA and its legion of willing sycophantic journalists will be right behind them attempting to explain why doctors should avoid any discussion with their patients about guns. The latest such effort comes from a right-wing blogger, Vic Khanna, who identifies himself as a health-care consultant and gun owner in an opinion-piece found on the Federalist blog.
The piece begins with the usual nonsense about how Obamacare is a threat to everything and that it threatens everyone's individual liberties, most of all the liberty to own a gun. This is the standard crap that has been promoted about every liberal program or policy since the Republicans realized that protecting the 2nd Amendment was a good wedge issue for them to use at the polls. But Khanna then goes into detail criticizing the efforts by Adam Goldstein and other physicians to create standards for judging CCW fitness among patients, an issue for which Goldstein has published several important peer-reviewed articles over the last several years.
Of course Khanna neglects to mention the fact that Goldstein, who happens to be Professor of Family Medicine at UNC-Chapel Hill, got into the CCW-competency business after receiving requests from sheriff's departments in North Carolina who are required under law to consult a physician if a person's mental or physical condition might make granting of CCW a risk. Now isn't that amazing? North Carolina actually had the good sense to codify a requirement that recognized the unique competencies of physicians in diagnosing mental or physical impediments to carrying around a gun. What? Let those gun-grabbing, elitist doctors decide whether you or I can walk around with a gun?
But Khanna isn't about to tell the truth and enlighten his readers to the fact that law enforcement is in kahoots with the medical establishment to keep North Carolina residents from carrying their guns. He's also unwilling to honestly summarize the gist of Adam Goldstein's publications on this issue, namely, the lack of clinical guidelines that physicians need to use when they diagnose all sorts of physical and mental conditions which might otherwise keep Americans from doing such non-essential activities as driving a vehicle or going to school. Perhaps in his role as a health care consultant Khanna tries to figure out ways to help parents avoid taking their children for the mandated health exam that most jurisdictions require before a kid can enroll in school.
Last year Adam Goldstein and other researchers sent out a questionnaire to 600 North Carolina physicians asking whether the recipients believed that they possessed sufficient medical knowledge to make a determination about the CCW fitness of individual patients. Of the 40% who returned the questionnaire, "a majority felt that they could not assess their patients' physical capability to carry concealed weapons," and nearly all the respondents felt that they needed special training before making medical assessments for CCW that might be required under North Carolina law.
Did Goldstein and his colleagues use these findings to promote the idea that issuance of CCW should be curbed or discontinued? No. Did they use these findings to challenge the rights of North Carolina resident to own guns? No. They did what the Hippocratic Oath requires them to do, namely, to raise concerns about their own ability to identify and reduce harm, in this case the harm that might occur if someone who was mentally or physically disabled could go around with a gun.
The NRA and its sycophant journalist crew like Vic Khanna have been playing fast and loose with the facts about physicians, patient care and gun ownership for the past twenty years. They've gotten away with it quite simply because most people visit doctors for medical conditions that don't involve guns. But the tide is beginning to turn, and when the American College of Physicians urges their members to 'educate' patients about guns, physicians like Adam Goldstein won't be turning to the likes of Vic Khanna in order to figure out how to respond.
Why Should Doctors Talk To Patients About Guns? Let The NRA Do It.
When the 11th Circuit re-instated the Florida gag law on physicians talking to patients about guns I knew that sooner or later we would hear from Timothy Wheeler and his gun-promoting group which believes that 19,000 gun suicides, 11,000 gun homicides and 50,000 (or more) intentional gun injuries each year shouldn't concern physicians at all. Wheeler is the doctor who began promoting the idea that doctors who inquire about gun ownership are their patients' worst enemies, and his organization is rolled out by the pro-gun lobby whenever they need additional ammunition to keep America from adopting a common-sense approach to the issue of gun violence.
Wheeler's organization, for which his claim of having thousands of members has never been verified in any way whatsoever, has just launched a small campaign to support the Florida gag law, at the same time that a coalition of medical associations and advocacy groups are going back to the 11th Circuit to ask the entire court, en banc, to overturn the recent ruling. Which is exactly why Wheeler and his buddies in the gun-blogging community are trying to tilt public opinion the other way.
In the interests of full disclosure, I should state that I am married to an attending pediatrician, and am also a member and certified gun trainer for the NRA. I have no issue with private ownership of guns but I take personally these indecorous attacks on physicians who are required to speak with patients about any matter which they feel might pose a medical risk, particularly involving something as potentially lethal as a gun. The shabby attempt by physicians like Wheeler to pretend that guns do not constitute a health risk reminds me of the pathetic charades conducted back in the 1950's by a few physicians and scientists who publicly disavowed any link between smoking and cancer.
Of course Wheeler and his cronies, in this case a psychiatrist named Robert Young, don't want their audience to believe that they are against safe use and storage of guns. After all, everyone's in favor of safe gun use these days, just ask the NRA and they'll tout their gun safety program, aka Eddie Eagle which has "reached more than 26 million children in all 50 states." The same website that contains this information about Eddie Eagle also states that the NRA is "not affiliated with any firearm or ammunition manufacturers," which is, simply put, a lie. But Dr. Young seems oblivious to the requirement in his own medical profession to base clinical decisions and strategies on evidence-based information, since he advises his medical colleagues to use the Eddie Eagle handouts in contacts with patients who might or might not own guns.
This guy's a physician? This guy took the Hippocratic Oath which requires him to counsel patients about risks to their health? There is not one single piece of credible research which shows that keeping a loaded, unlocked gun around the house creates protection from crime that outweighs the risks of injury or death from the existence of that gun.
People like Robert Young and Timothy Wheeler find media outlets for their destructive ideas because we really are committed to the idea of hearing "both sides" in the public policy debate. But I don't think that there are two sides when it comes to discussing a health issue which claims 80,000 or more victims each year. Unless, of course, you'd rather believe that mortality and morbidity at those levels has nothing to do with health at all.
In 2011 the Florida legislature passed a law to protect the state's gun owners from having to divulge any information about gun ownership during the course of a medical exam. The law, which became known as 'Docs Versus Glocks,' soon became one of the main poster children of the pro-gun, anti-gun argument that really heated up after the carnage at Sandy Hook. On one side stood the NRA, which touted the law as a defense of 2nd Amendment rights; on the other side was Brady and the medical community which viewed the law as interfering with the doctor's right to know. The law was struck down in 2012 by a Federal District Judge and was immediately appealed by the Gunshine State to the 11th Circuit which held a hearing in July, 2013. Everyone's expecting a ruling soon so I thought I would take the opportunity to discuss the case before all the real experts get into the act.
The law doesn't completely deny physicians the ability to talk to patients about guns. What the law actually says is that a physician "shall refrain" from inquiring about firearm ownership unless the practitioner "in good faith believes that this information is relevant to the patient's medical care or safety, or the safety of others…." Yet despite this caveat, the medical community attacked the law, declaring that its language would have a chilling effect on the ability of physicians to talk to their patients about all kinds of safety and health issues, not just about guns. The District Court sided with the docs, calling the law a "legislative illusion" because there was no connection between questions asked about gun ownership and protecting the 2nd Amendment right to own guns.
While arguments over gun control at the federal level get all the headlines, it's what happens at the state and local levels that really determines whether or not gun owners can get or keep their guns. The Sullivan Law has been in existence since 1908, it's almost impossible to own or carry a gun in New York City and 2nd Amendment 'rights' can go fly a kite. In total dollars the NRA gives out less than half a million to state-level candidates and parties, but this is 30 times more than gun control groups give to the same races. And in a state-level race where 200 or less votes can make the difference, getting your hands on an NRA phone list may carry the day. I'm not sure that the Florida legislators who voted for the gun bill knew or even cared what the law said. But they didn't want to be 'scored' by the NRA in the next election because they voted the wrong way. Before the Tea Party showed up it really didn't matter whether a Republican toed the line on gun issues because the NRA wasn't about to support any Blue candidates anyway. But now that a growing number of Republican office-holders face primary challenges from the Right, everyone on the Red side of the aisle is listening to the NRA.
As for doctors, it took them nearly a century after 1850 to become a self-regulating profession whose guidelines for practice and behavior were largely established and maintained by themselves. And even though their professional autonomy has of late come into conflict with the market imperatives of insurors and other for-profit enterprises, they still retain sovereignty over defining how to deliver their services at the point that such services matter most, namely, in consultations with patients. The fact that the Florida legislature didn't bother to ask their own state Health Department for a recommendation on physicians talking to patients about guns tells me that the motive behind the law had nothing to do with concerns about the delivery of health care at all. For that matter, it wasn't that the law threatened doctors who talked to their patients about guns per se, it was the fact that any law which infringes on the professional autonomy of physicians to communicate with their patients threatens the validity of the Hippocratic Oath.
Let's hope that the 11th Circuit understands what this argument is really all about.


Every 10 minutes, the Teddy's platform tracks all commercial flights that we are scheduled to meet. Even then, exclusively at Teddy's, the first hour is free for pickups at airports in our primary markets: LaGuardia, White Plains, JFK, Newark Liberty, Tweed New Haven and Bradley International in Hartford/Springfield. After that we charge by the quarter-hour at our standing hourly fare for each vehicle style. Outside of our primary markets, graced wait charge policies vary.
Protocol A: Once a flight approaches the destination airport, meaning we have to be there, but then diverts and lands elsewhere, we default to cancelling that car (industry-best late-cancellation charges apply) and rescheduling another vehicle once you are airborne again for final arrival at the scheduled airport. This protocol cuts your cost for what could otherwise become a lengthy and costly stay at the standby airport.
In Teddy's primary markets, the first quarter-hour is free, after which we charge by the quarter-hour.
Email: Do not use email for last-minute communications. We attempt to respond quickly to contact@teddyslimo.com but urge you to monitor email conversations to be sure we respond in time.
Online trip management: Access the login via Online Reservation.
 We do not track flights that we are bringing you to an airport to catch.


text:
Proof of water for future explorers: New images from NASA show "underground ice cliffs" on Mars
01/20/2018 / By David Williams
It has been known for quite some time now that Mars is full of water. Regardless of whether or not there is actually flowing water on the so-called red planet's surface, scientists from the National Aeronautics Space Agency (NASA) have long confirmed that water is indeed present on the planet. Most of it is in the form of ice, and now in a new paper, it has been revealed that there are potentially massive "underground ice cliffs" lying deep beneath the planet's surface.
In a new paper titled "Exposed subsurface ice sheets in the Martian mid-latitudes," scientists have detailed a new discovery of so-called water ice cliffs, most of which are currently sublimating due to exposure to the planet's atmosphere. According to a quick description, the cliffs are "composed mostly of water ice," with ice sheets that "extend from just below the surface to a depth of 100 meters or more."
The discovery of these ice cliffs has now triggered widespread speculation about what it could mean for the future of Mars exploration. According to one expert who worked on the paper that details the discovery, it could lead to great new leaps in research regarding the search for life on the neighboring planet.
According to Shane Byrne, an assistant professor from the University of Arizona Lunar and Planetary Laboratory and co-author on the study, the water that can be extracted from the ice cliffs that were only just discovered could lead to a steady source of water for the humans that would eventually explore Mars.
"Humans need water wherever they go, and it's very heavy to carry with you," said Byrne. "Previous ideas for extracting human-usable water from Mars were to pull it from the very dry atmosphere or to break down water-containing rocks. Here we have what we think is almost pure ice water buried just below the surface."
The next step that needs to be done is essentially to just collect the water from under the Martian planet's surface. And based on the composition as well as the location of the water ice cliffs on Mars, one could very well do it with nothing more than just a shovel and a bucket.
Byrne notes that "a high-tech solution" wouldn't be necessary for the extraction. "You can go out with a bucket and shovel and just collect as much water as you need. I think it's sort of a game-changer," he said.
Based on data gathered from the Mars Reconnaissance Orbiter (MRO) and its Compact Reconnaissance Imaging Spectrometer for Mars (CRISM), the material in the Martian areas referred to as ice cliffs is indeed frozen water. And according to the Thermal Emission Imaging System (THEMIS) camera onboard the Mars Odyssey orbiting spacecraft, the surface temperature confirms that the scientists weren't just seeing thin front on the ground.
According to MRO Deputy Project Scientist Leslie Tamppari of NASA's Jet Propulsion Laboratory (JPL) in Pasadena, California, water samples from the ice cliffs could likely serve as the key to detailed information on Martian climate in the past. "If you had a mission at one of these sites, sampling the layers going down the scarp, you could get a detailed climate history of Mars," she said.
There's no telling exactly what NASA will reveal next about Mars following this new discovery, but with every new find, scientists are surely inching closer and closer to finding and eventually revealing signs of life outside of Earth. That will surely be a sight to behold.
Explore more news about Mars and other planets at Space.news.
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Tagged Under: future science, ice cliffs, Life on Mars, Mars, Mars ice, NASA, Space, space exploration, water ice
The Milky Way had a large sibling that we never knew existed, because Andromeda ate it billions of years ago
10/17/2018 / By Edsel Cook
Researchers look at how some tropical tree-hugging lizards are able to survive severe wind storms
Scientists discover marbled crayfish that didn't exist 25 years ago but are somehow able to clone themselves
Art project aims to generate music that can be heard by aliens wherever they are in the universe
Dust in the wind might have brought us life: Research suggests life on our planet may have begun with tiny organisms brought here by space dust
12 new moons discovered orbiting Jupiter, and one of them is a real oddball
Cool survival technique: Shrew skulls shrink during winter to reduce food requirements, then regrow in spring, according to new research
09/27/2018 / By Zoey Sky
Space probe records Saturn "singing" to its weirdest moon
Left-wing news sites say weather control is impossible, then they claim Trump is generating hurricanes
Wealthy elitists literally living off blood transfusions from children … Modern "vampires" are real
09/13/2018 / By Tracey Watson
NASA appoints "planetary protection officer" to act as an intermediary between humans and extraterrestrial life
Asteroid belt used to be a planet that was destroyed by nuclear war? Analysts hypothesize alternative space history
The faint stream emanating from star systems could be caused by DIAMONDS
09/09/2018 / By RJ Jhonson
U.S. diplomats in Cuba were attacked by "microwave beam weapons"
Astrophysicist claims that aliens are racing against dark energy, capturing stars from other galaxies, reeling them in, and harvesting their resources
We are pre-wired to perceive wrinkles around the eye as conveying more sincerity: Study
COOL science: How to bring out extraordinary abilities hidden in your brain
Scientists "break technical barrier" that's preventing the cloning of primates, including humans
New use for drones: Japanese company will use them to annoy overtime staff to get them to leave
Scientists develop "synthetic bioluminescent molecules" to make cells glow bright enough to be seen from outside the human body


TCB Tattoo, a professional tattoo studio specializing in all tattoo styles, is open for business. The locally owned and operated studio is located at 18 W Bridge Street in downtown Oswego, NY. and is the realized dream of Charles Spataro and Sarah Dehaba, proprietors.
TCB opened their doors this past February in order to address the ever growing popularity and demand for quality tattoos. TCB is looking to add artists at their West Bridge Street location. "We will be very discerning when choosing new artists to represent our brand." said Spataro "It is important to us to provide top quality tattoos to our clients and that requires talented artists."
The studio has already been an asset to the community with their donations to various local non-profit organizations. "We plan on being involved as much as we can for the well-being of the city" says co-owner and manager Sarah Dehaba "We are community minded business owners with a genuine love for Oswego."
You can find TCB Tattoo on Facebook at www.Facebook.com/tcbtattoooswego or call them at (315) 343-1300.
Hours of operation are Tuesday through Friday from 12 pm – 9 pm. Saturday from Noon – 11 pm. and Sunday; Noon – 6 pm.
I would like to be a free human canvas! Free for me and experience for your new artists!
TCB is a very professional and friendly business. I look forward to doing business with them soon!


« Austin Weird Homes Tour!
Happy Memorial Weekend Everyone!! I hope everyone has a fantastic weekend celebrating with friends and family. I wanted to take a moment to remember all of those brave men and women who valiantly fought for our freedom and for those who continue to do so today. Without them it would not be possible for us to lead the lives that we do. They're courage and commitment to our country is what makes them truly heroes. Thank you to all in the armed services who so selfishly give up their lives so we can live ours!


The short-term variability of active galactic nuclei is often being linked with a presence of hot spots residing on the surface of an accretion disc. We apply the theory of random point processes to model the observed signal from an ensemble of randomly generated spots and to reproduce typical features that are found by fourier-analysing X-ray lightcurves from galactic centres.
Theory of random processes provides a mathematical tool to describe the fluctuating signal from accreting sources, such as active galactic nuclei and Galactic black holes observed in X-rays. These objects exhibit featureless variability, which appears on different timescales and is thought to originate from an accretion disc.
In our research, we study a general framework with the focus on statistical approach, which permits semi-analytical determination of the expected power spectral density (PSD) of the resulting lightcurves. Fluctuations of the signal are assumed to be governed by the Poisson or by the Hawkes processes. The latter one represents an avalanche mechanism and seems to be suggested by the observed form of the power spectrum. We thus investigate how the local processes generating the spots and flares on the disc affect the power spectrum of the outgoing radiation. We include general relativity effects shaping the signal on its propagation to a distant observer.
As a case study, we analyse a `spotted' accretion disc lightcurves for a range of parameters. The asymptotic slopes of PSD are 0 at low frequencies and they tend to -2 at high frequencies, usually with a single frequency break. More complex, two-peak solutions also occur; for example, a doubly-broken power law profile. The amplitude of the peaks and their frequency difference depend on the inherent timescales of the model.


Item #787-D is genuine Pitney Bowes postage meter ink to be used in the SendPro® P/Connect+®Series postage meters. Pitney Bowes supplies are designed and tested within their respective postage meters. The 787-D cartridge does not prematurely dry up. High print quality is assured each time.
Our SendPro P/Connect+ Series postage meters and cyan ink have been approved by the USPS. Our meter ink fully meets all USPS requirements.


text:
New u-blox M8 Firmware Now Supports Galileo, Increases GNSS Signal Acquisition Sensitivity and Security
u-blox modules
Thalwil, Switzerland–based u-blox has announced the upcoming release of a new firmware, FW 3.01, for its u-blox M8 multi-GNSS platform.
u-blox M8 FW 3.01 will now also support Galileo in addition to GPS, GLONASS, BeiDou. It can track up to three constellations concurrently and makes use of all satellite-based augmentation system (SBAS) signals and Japan's Quasi-Zenith Satellite System (QZSS) at the same time, according to the company.
Products with FW 3.01 in ROM will become available in the second quarter of 2016. Firmware to upgrade existing flash-ROM based u-blox M8 products can be downloaded from the u-blox website.
Once Galileo is fully deployed, the European GNSS will provide access to 24 additional satellites, thereby significantly increasing availability of GNSS signals and further improving position accuracy in challenging urban environments. u-blox M8 supports Galileo-based eCall, the European emergency call system, which will be required in new vehicles starting 2018. u-blox M8 is also compliant with ERA-GLONASS, eCall's Russian equivalent.
In addition, with FW 3.01, the u-blox M8 has increased BeiDou acquisition sensitivity and adds support to the Indian GAGAN augmentation system.
M8 chips and modules are able to operate reliably in difficult environmental conditions as well as in a security attack scenario,l u-blox says. Because a growing number of wireless systems rely on GNSS positioning, the threat of attacks, such as diversion of drones or hijacking of car electronics, has become very real.
Security mechanisms are now embedded in FW 3.01, the result of years of intense research at u-blox R&D labs, the company says. An anti-spoofing feature detects fake GNSS signals, and a message integrity protection system prevents "man-in-the-middle" attacks. Yet another security function detects and suppresses jamming. Since all this functionality is already built into the M8 FW 3.01, these security mechanisms are a lot more effective than an external system implementation, u-blox suggests.
Automotive-grade M8 products benefit from an extended operating temperature of -40 to +105°C and are AEC-Q100 Grade 2 qualified. The extended temperature range allows more flexibility in vehicle integration, for instance by integrating an M8 GNSS receiver into a roof-top antenna where temperatures can reach 105°C, according to the company.
The company says that the FW 3.01 has reduced power requirements by 10 percent compared to earlier firmware versions of the M8.
The u-blox M8 platform supports applications where navigation performance, reliability, and high accuracy are paramount, whereas the recently announced u-blox 8 platform addresses power sensitive applications such as wearables. u-blox M8 and u-blox 8 products are pin- and software compatible.
Septentrio's 4.2 Firmware Designed to Deliver Performance,…
NovAtel Now Delivering Enhanced Signal Acquisition, Time and…
Figures 7, 8, 9 & 10: Inter-Signal Correction Sensitivity…
Figures 4, 5 & 6: Inter-Signal Correction Sensitivity…


text:
"""Device placement and data parallelism."""
from __future__ import absolute_import
from __future__ import division
from __future__ import print_function

import inspect
from tensor2tensor.utils import expert_utils as eu
import tensorflow as tf

def data_parallelism_from_flags(daisy_chain_variables=True, all_workers=False):
  """Over which devices do we split each training batch.

  In old-fashioned async mode, we split the batch over all GPUs on the
  current worker.

  In sync mode, we split the batch over all the parameter server GPUs.

  This function returns an expert_utils.Parallelism object, which can be used
  to build the model.  It is configured in a way that any variables created
  by `tf.get_variable` will be assigned to the parameter servers and shared
  between datashards.

  Args:
    daisy_chain_variables: whether to copy variables in a daisy chain on GPUs.
    all_workers: whether the devices are all async workers or just this one.

  Returns:
    a expert_utils.Parallelism.
  """
  dp_arg_names = inspect.getargspec(data_parallelism).args

  blacklist = ["daisy_chain_variables", "all_workers"]

  kwargs = {}
  for arg in dp_arg_names:
    if arg in blacklist:
      continue
    kwargs[arg] = getattr(tf.flags.FLAGS, arg)

  return data_parallelism(
      daisy_chain_variables=daisy_chain_variables,
      all_workers=all_workers,
      **kwargs)

def data_parallelism(daisy_chain_variables=True,
                     all_workers=False,
                     ps_replicas=0,
                     ps_job="/job:ps",
                     ps_gpu=0,
                     schedule="continuous_train_and_eval",
                     sync=False,
                     worker_gpu=1,
                     worker_replicas=1,
                     worker_id=0,
                     gpu_order="",
                     worker_job="/job:localhost",
                     no_data_parallelism=False):
  """See data_parallelism_from_flags."""
  tf.logging.info("schedule=%s" % schedule)
  tf.logging.info("worker_gpu=%s" % worker_gpu)
  tf.logging.info("sync=%s" % sync)
  def _ps_replicas(all_workers=False):
    if all_workers:
      return list(range(ps_replicas))
    # Worker K will be using replicas {0,...n-1} + K*n if we have n replicas.
    num_replicas = ps_replicas // worker_replicas
    return [d + worker_id * num_replicas for d in range(num_replicas)]

  def _gpu_order(num_gpus):
    if gpu_order:
      ret = [int(s) for s in gpu_order.split(" ")]
      if len(ret) == num_gpus:
        return ret
    return list(range(num_gpus))

  def _ps_gpus(all_workers=False):
    ps_gpus = []
    for d in _ps_replicas(all_workers=all_workers):
      ps_gpus.extend([(d, gpu) for gpu in _gpu_order(ps_gpu)])
    return ps_gpus

  def ps_devices(all_workers=False):
    """List of ps devices (where to put the experts).

    Args:
      all_workers: whether the list is for all async workers or just this one.

    Returns:
      a list of device names
    """
    if ps_replicas > 0:
      if ps_gpu > 0:
        return [
            ps_job + "/task:%d/GPU:%d" % (d, gpu)
            for (d, gpu) in _ps_gpus(all_workers=all_workers)
        ]
      else:
        return [
            ps_job + "/task:%d" % d
            for d in _ps_replicas(all_workers=all_workers)
        ]
    else:
      if worker_gpu > 0:
        return ["gpu:%d" % d for d in _gpu_order(worker_gpu)]
      else:
        return [""]

  def _replica_device_setter(worker_device):
    if ps_replicas == 0:
      return worker_device
    return tf.train.replica_device_setter(
        worker_device=worker_device,
        ps_tasks=ps_replicas,
        ps_device=ps_job + "/GPU:0" if ps_gpu > 0 else ps_job)

  is_single_machine = ps_replicas == 0 and worker_replicas == 1

  if no_data_parallelism:
    datashard_devices = [""]
    caching_devices = None
  elif is_single_machine:
    tf.logging.warn(
        "Schedule=%s. Assuming that training is running on a single machine.",
        schedule)
    datashard_devices = ["gpu:%d" % d for d in _gpu_order(worker_gpu)]
    if worker_gpu < 1:
      datashard_devices += ["cpu:0"]
    caching_devices = None
  elif sync and ps_replicas > 0:
    # compute on ps
    datashard_devices = [
        _replica_device_setter(d) for d in ps_devices(all_workers=all_workers)
    ]
    if ps_gpu > 0 and ps_replicas > 1:
      caching_devices = [
          ps_job + "/task:%d/cpu:0" % d
          for (d, _) in _ps_gpus(all_workers=all_workers)
      ]
    else:
      caching_devices = None
  else:
    # compute on worker - this is either a single-worker setup or asynchronous
    # with parameter servers.
    if worker_gpu > 1:
      datashard_devices = [
          _replica_device_setter(worker_job + "/GPU:%d" % d)
          for d in _gpu_order(worker_gpu)
      ]
      caching_devices = None
    else:
      datashard_devices = [_replica_device_setter(worker_job)]
      caching_devices = None
  tf.logging.info("datashard_devices: %s", datashard_devices)
  tf.logging.info("caching_devices: %s", caching_devices)
  tf.logging.info("ps_devices: %s", ps_devices(all_workers=all_workers))
  return eu.Parallelism(
      datashard_devices,
      caching_devices=caching_devices,
      daisy_chain_variables=daisy_chain_variables,
      ps_devices=ps_devices(all_workers=all_workers))

redpajama_set_name: RedPajamaGithub


Andre Clyde Cave, 35 years, aka "Snopps or Snopp Dre" last known address Fairfield Cross Road, Tudor Bridge, St. Michael, who was the subject of a wanted notice, was captured during an operation by Police in the Cane Garden, St. Thomas community.
He is currently in custody assisting with a major investigation.
On 28 April 2014, an operation was carried out by Police in Cane Garden, St. Thomas, where a motor car driven by Johnson was intercepted and she held along with the wanted man. A searched of the car revealed eight Ziplock bags with a quantity of cannabis and a grey piece of plastic with a loose quantity of cannabis.
Johnson made an appearance at the Magistrate's Court on Wednesday 30 April 2014.


UNLIKE women, men can continue having children into old age, but those kids may pay a small price – in intelligence.
Children born to older dads score lower on average on a range of tests, including concentration, memory, reasoning and reading, while the kids of older mothers score higher than those of younger mothers. That's according to John McGrath at the University of Queensland in St Lucia, Australia, and colleagues, who analysed data on more than 33,000 US children taken at 8 months and again at 4 years and 7 years (PLoS Medicine, DOI: 10.1371/journal.pmed.1000040).


text:
Don't settle for average. Get a badass website like the pros.
BMO profit jumps 33% to $1.6B
topdid.com December 1, 2020
BMO Financial Group says it is winding down its non-Canadian investment and corporate banking business in the energy sector as the bank topped expectations with a $1.6-billion profit in its latest quarter.
Chief executive Darryl White said Tuesday the move is part of BMO's efforts to better allocate resources in places where they can deliver strong returns now and in the future.
"Going forward, BMO Capital Markets' energy business will be focused on the Canadian energy market, where we believe our competitive positioning is strongest and where we will continue our deep and long-standing commitment to supporting clients," he told analysts on a conference call to discuss the bank's latest financial results.
White's remarks come as Canadian banks and the country's economy are trying to stage a rebound from the COVID-19 pandemic, which prompted governments and financial institutions to streamline their processes and dig into their coffers to offer relief.
Despite the added pressures and a recent second wave of the virus, BMO reported Tuesday a fourth-quarter profit of nearly $1.6 billion or $2.37 per share, up from nearly $1.2 billion or $1.78 per share a year ago.
On an adjusted basis, BMO says it earned $2.41 per share, down from an adjusted profit of $2.43 per share in the same quarter last year.
Analysts on average had expected an adjusted profit of $1.90 per share, according to financial data firm Refinitiv.
Revenue totalled nearly $6 billion, down from almost $6.1 billion in the same quarter last year.
White indicated that things continue to look up for the bank — one of the reasons why it was able to start paring back the amount of money it is putting aside to account for bad loans.
Total provisions for credit losses amounted to $432 million, up from $253 million a year ago, but down from nearly $1.1 billion in its third quarter.
BMO will continue to be disciplined with its expense management and efforts to bring efficiency to its operations, White said.
"While we expect revenue growth in parts of our business could remain constrained in the near term, we are committed to our financial objectives over the medium term," he said.
The bank, White added, has already strengthened its competitive and capital position and identified opportunities to grow as business investment and consumer spending recover and the globe gets better at managing COVID-19.
"Looking ahead to 2021, while the path of the pandemic and the economic recovery remains uncertain, we now know that vaccines will be available relatively soon, and there's good reason to be optimistic about the associated economic recovery accelerating as 2021 progresses."
SOURCE: CBC.ca
topdid.com June 5, 2020
Bouncing back? Canada added 290,000 jobs in May
topdid.com July 24, 2018
Trade Tribunal finds subsidies and dumping of steel products causing harm
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Kiwi kayaker Nikki Kelly has been on the water since she was 16 years old - chasing a hot instructor who never knew the effect he had on her.
In the last few years, she was named greatest kayaker of the 20th century by LVM, competed and won many races at the Teva Mountain Games and Ford George Games (Extreme Champion 2002) while taking part in rodeo kayaking, creeking, expedition kayaking and a little surf-kayaking. Plus more than a little raft-racing. In an interview with River Angels, she described her training routine as: "Kayak, kayak, and more kayak. Off season is gym, yoga, waka ama, mountain bike, every day as often as possible and when body allows - variety is the spice of life."
Kelly herself names the 7 Rivers expedition in California - 50 days of non-stop paddling - as the highlight of her career ... so far.
What's the longest sports event you've taken part in?


For Tomas O'Brian. I am one of John Holloway's granddaughters. The family has little information about him. He had six sons (4 of whom died in childhood) and two daughters. He is buried in Emly Churchyard in a family grave (although incorrectly marked as "William" who was his brother). May I ask why you are enquiring about him ?
Marilyn Shanahan, My great great grandfather, James Carroll, of Emly, married Alice Bourke from Coolboy, Limerick. They married about 1830, and lived in the Parish of Emly. Is any of this familiar to you?
Hello Emly and Fr. Rochford. My grandfather, born in Emly was Tobias Bourke Ryan in 1873. His father Patrick Ryan born 1839 in Tipp married Johanna Bourke born in Tipperary also.(Her parents being William Bourke and Mary Fleming. Seeking Patrick's father Thomas born in Tipp. Also Johanna Bourke Ryan was living in 1911 at age 72 with a niece Margaret Bourke and a nephew David Bourke in Tipperary. Are they familiar to anyone?
This is for James Muhs -- my great great grandfather, John Hagney (Haigney according to Tipperary baptism research, came from Parish Emly, County of Tipperary. He named one of his sons Joseph Terrance. He came to NYC around 1850 (born 1829) and while living in NYC, records show his name as Hagney and Hageney. I would be very interested in connecting with you to discover shared ancestors! My email is kathleenh@yahoo.com.
My dad, Thomas Ailbee Hayes, was born in Emly, 12/15/1907. He had 5 brothers, Jack (John), James, William, Christopher, all of whom emigrated to New York, USA & stayed except for William who returned to Emly. He had one sister Mary, who also stayed in Emly. Another brother Michael? died at a young age in Ireland. Hoping to visit in next year or 2. I know I have several cousins there. My sister Erin, visited in Sept.of 2014. There are several of us here in NY area and we keep in touch. My dad also had a cousin Thomas M. Hayes, who emigrated here also, & we saw all the time. It was a fun time growing up with this large extended Hayes family.
My name is Michael Carroll, and my family tree has roots in Emly. My great-grandparents were Owen and Mary Carroll (maiden name, Brennan), who lived in Ballyvistae according to the 1901 census. Owen's mother (my great, great grandmother) was named Alice Bourke (maiden name) of Coolboy. I do not know my great great grandfather's name (the one who married Alice Bourke). I am writing to ask if their is anything in your records that might help. They had 12 children including my great grandfather, Owen. I intend to commission a search through Tipperary Family History Research , but I would like to start with the most distant ancestor I can determine the name of. My best guess is that his name was James Carroll, as my family seemed to follow the Irish tradition of naming the 1 st child after the paternal grandfather. I was fortunate enough to visit Emly this September. I found it to be a friendly, charming area. I can understand why you won the "Tidy Town" award. Thanks you for any help you may be able to give me.
I am looking for any descendants of Owen and Mary Carroll, of Ballyvistae (Emly). They were my great grandparents. Owen was born in the 1840's. I recently visited Emly on a trip from USA. Your town is beautiful, and the people are very friendly. I'm proud that my people came from your town.


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I don't think anyone enters a marriage expecting it to fall apart. After all, at one time or another, you will have loved each other so immensely, that you agreed to spend the rest of your lives together. But in time, things can happen and marriages can breakdown. Divorce rates are rising as it can be easier now to pull the plug on the marriage and walk away. But it is also seen as quite an expensive thing to do.
If you have both decided that this is no longer going to work, and you are being fairly amicable about it, then having a clean break can be easier and far less expensive than you previously thought. I wanted to share with you some of the things you could consider if you have decided there is no other route to take.
One of the first things you may want to do is find a decent lawyer to help with the legal side of things. While you can manage a lot of yourself, there are legal documents that need to be generated so that you can move on with your lives. A quick look online will help you to find a lawyer as you might want to look out for recommendations or referrals. Getting someone on side is key to ensuring that you can move this process on as quick as possible, without the need for arguments or lengthy court hearings.
The financial side of things can often be the most tricky, so if you are remaining amicable then this element could be something you tackle on your own. An easy fix would be to split everything down the middle, including all assets, which in most cases is what should happen as a marriage is a partnership. Getting layers involved in this process can mean that you are due for lengthy discussions, but if you are both being transparent and can easily divide things up, save yourself the costs and agree on a process moving forward.
While it may be amicable now, as discussions move to family and children, if you have them, and money, emotion can really set in and this is when things can turn from good to bad. It is so important in these circumstances to remain as amiable as possible. This helps you to keep things on track and moving forward.
Communication is important, after all, it can be one of the fundamental factors of keeping a relationship a love. So you do need to keep the communications line open to ensure that you can discuss things amicably in the future. Who knows, doing this could even help you on trac for reconciliation. Many couples find that starting these proceedings makes things final, and often find that they want to give things one last chance before signing off for good. It gives you time to really think about what you want.
Finally, always give yourself some personal time to ensure that you are clear in your mind about the plans and steps forward. It doesn't need to be an expensive break up, if you are both on the same page. But equally it may not even need to go down that route at all. I hope this gives you the guidance you need to avoid a hefty divorce bill.
Sick of Painfully Expensive Dental Bills?
How Stringent Is Your Financial Safety Net?
Unhealthy Habits Uncovered: What's Causing Your Increasing Debt?


text:
Samsung's browser is now available for its Wear OS smartwatches
Samsung has brought its Samsung Internet web browser to the new Wear OS-based Galaxy Watch 4 (via 9to5Google). Browsing on a watch doesn't sound like my ideal way to surf the web for a long period of time, but I could see how it could be useful for small tasks like checking a name or looking up a place.
I don't have a Galaxy Watch 4, so I can't give you hands-on experience of how the Samsung Internet browser works. But based on 9to5Google's testing, it seems like Samsung has thought of some neat tricks to make it possible to navigate the web on your wrist:
An obvious question about a web browser on your wrist is how exactly that tiny, circular display can manage to show full webpages. Samsung's answer is with gestures. A guide will come up when you navigate to your first webpage that explains a diagonal swipe from either side of the screen will allow users to get to the corners of a webpage. Meanwhile, a swipe up reveals options for bookmarks, "Zoom mode," and a shortcut to send the webpage directly to your connected phone.
This new browser only adds to what you can already get with the Galaxy Watch 4 series of smartwatches, which we thought were pretty good — as long as you're already using a Samsung phone, that is. It should be noted that a browser on a smartwatch isn't new, though; Samsung also has a browser for its Tizen-based smartwatches, and even the Apple Watch has built-in browsing capabilities (though there's no dedicated Apple Watch version of Safari).
Google and YouTube will cut off ad money for climate change deniers
Foundation is getting a second season on Apple TV Plus
Firefox's address bar has ads now, but you can disable them
The easy way to install Windows 11 on unsupported CPUs


text:
Year : 2011 | Volume : 1 | Issue : 1 | Page : 1
Introductory Editorial
M Mohamed Essa
Editor in Chief - International Journal of Nutrition Pharmacology Neurological Diseases, Department of Food Science and Nutrition, CAMS, Sultan Qaboos University, Oman; Department of Pharmacology, School of Medical Sciences, UNSW, Australia Developmental Neuroscience lab; and Department of Neurochemistry, NYSIBR, Staten Island, NY, USA
Date of Web Publication 11-Mar-2011
DOI: 10.4103/2231-0738.77514
Essa M M. Introductory Editorial. Int J Nutr Pharmacol Neurol Dis 2011;1:1
Essa M M. Introductory Editorial. Int J Nutr Pharmacol Neurol Dis [serial online] 2011 [cited 2020 Jan 17];1:1. Available from: http://www.ijnpnd.com/text.asp?2011/1/1/1/77514
I am pleased to announce the launch of the International Journal of Nutrition Pharmacology Neurological Diseases - a new peer-reviewed, open-access journal published by Medknow Publishers.
The International Journal of Nutrition, Pharmacology, Neurological Diseases (IJNPND) is an international, open-access, peer-reviewed journal that covers all fields related to nutrition, pharmacology and neurological diseases. There is no other journal that focuses on the nutrition, pharmacology and neurological diseases in a combined form, and IJNPND aims to fill this void and provide a forum for those with an interest in these areas. IJNPND has three main sections: nutrition, pharmacology and neurological diseases. IJNPND publishes research papers, review articles, commentaries, case reports, brief communications and correspondence in all three sections. Reviews and commentaries are normally commissioned by the journal, but consideration will be given to unsolicited contributions.
In the nutrition section, IJNPND welcomes research papers including all aspects of experimental/clinical nutrition and invited articles/reviews/commentaries on nutritional issues. In the pharmacology section, IJNPND welcomes contributions in all fields of pharmacology (both basic and clinical). The work should have a direct bearing on the drug effects, mechanisms or uses, or the development of new drug targets. In the neurological diseases section, IJNPND publishes papers on a broad range of topics of general interest to those working in all the neurological diseases. IJNPND is also ready to publish the proceedings of international conferences/symposia in the thrust areas of the journal.
All articles published in IJNPND will be abstracted and indexed in Caspur, EBSCO Publishing's Electronic Databases, OpenJGate, PrimoCentral, ProQuest, SCOLOAR, SIIC databases, Summon by
Open access means that all articles are freely available to all, worldwide, at no cost to the reader, meaning that the publication cost should be covered by the author's institution or research grant funds. Fee waivers and discounts are available on a case-by-case basis, and we shall make every effort to ensure that lack of funds does not impede the overall objective of publishing the best science, irrespective of authorship or country of origin. Open access is of huge benefit to the researchers working in institutions around the globe where institutional libraries are unable to subscribe the full range of journals.
I expect that the International Journal of Nutrition, Pharmacology, Neurological Diseases will attract manuscripts of the highest quality that are of greatest possible benefit to readers. Peer review is undertaken by at least two leading experts in the area of the manuscript.
For further information on what we hope will be an exciting and highly useful new journal, please click on the "about this journal" link on the journal's web page ( http://www.ijnpnd.com ).
Essa M M
Advertise | Sitemap | What's New | Feedback | Disclaimer|
© International Journal of Nutrition, Pharmacology, Neurological Diseases | Published by Wolters Kluwer - Medknow>
Online since 20th September, 2010


Welcome to a guest post from Kate. Most of you possibly already know Kate through Twitter or her blog. What you may not know is that Kate used to work in IT support and has offered the recount of a very funny phone call as a guest post.
When I saw that Nickie was after some guesties to cover her holidays, I immediately thought of a subject to write about, Y'see, before I became a blogger, I worked in IT Support for 22 years.
And that, of course, means the IT helpdesk. Where every "IT assistant" starts their career – in fact most IT professionals seem to start there. You know why? Because no bugger else wants to do it. Helpdesks can be thankless places to work. People just want problems fixed but you're often battling their IT knowledge and understanding of your instructions. I hate ringing helpdesks now because they tell me to try things that have me protesting "I've already done that" or "that's not going to fix the problem, is it?" I'm a user that helpdesks detest – the know-it-all – and I spoke those words this morning and ended up fixing the fault myself. This is however infinitely better than the fiddlers who muck around with settings because they think they know it all but don't, then deny it all when they break it. A little knowledge is indeed a dangerous thing.
My first IT support job was working on a helpdesk of an accountancy software house in 1984 – PCs were still rare beasts and Unix based multi-user systems felt very high tech because they didn't need to be housed in a whole room. And yet, I bet my phone has more processing power and disk space than one of those. (And has a colour screen!) And talking of phones, we didn't even have mobiles. The first mobile I ever had was about 9 years later, when I was given one by work. I could only use it in certain places and I could kill with a swing of my handbag.
My "customers" were largely dealers , who should have been more knowledgeable. Not always true. One day, I asked one if she had a fax machine – because these too were rare beasts and it was before email – and she replied that no, she didn't, she had a PC.
"Because I'm in a phone box and the PC is in my office at home".
She repeated the words out loud to the rest of the office and the place erupted in laughter.
It's moments like those that encapsulate life on an IT helpdesk. Filled with frustrations, but sometimes, you've just gotta laugh. Oh and the title? Words spoken by helpdesk workers the world over – but you know what? It does work more times than you would believe!


text:
Religious leaders talk about healing after mass shootings
by: Heather Olinger, Associated Press
Leaders of churches and a synagogue that were victimized by violent hate crimes are talking about how they helped their congregants heal.
The leaders are attending a meeting Monday evening at the Washington National Cathedral along with District of Columbia religious leaders and law enforcement.
Officials say it's the first time they have all gathered.
Leaders from Emmanuel AME in here in Charleston, the Tree of Life Synagogue in Pittsburgh and the First Baptist Church in Sutherland Springs, Texas, are attending the meeting, district officials say.
Nearly four dozen people were shot and killed in separate attacks at their institutions.
Metropolitan Police Chief Peter Newsham says bias crimes are up in the district and District police are enhancing security efforts.
HOLLYWOOD, S.C. (WCBD) – Authorities responded to a report of gunshots fired at a residence in the town of Hollywood early Friday morning.
According to Capt. Roger Antonio with the Charleston County Sheriff's Office, it happened shortly after midnight in the 4800 block of Highway 164.


text:
Pustoška () je město v Pskovské oblasti Ruské federace. Při sčítání lidu v roce 2010 mělo 4619 obyvatel.

Poloha
Pustoška leží na řece Krupeje, přítoku jezera Jezerišče v povodí Narvy. Od Pskova, správního střediska oblasti, je vzdálena přibližně 190 kilometrů na jih.

Doprava
Od roku 1901 vede přes Pustošku železniční trať z Moskvy do Rigy.

Jižně od města je dálniční křižovatka dálnice M9 z Moskvy do Velikých Luk a dál do Rigy s dálnicí M20 z Petrohradu přes Něvel do Běloruska a do ukrajinské Oděsy.

Dějiny
Za druhé světové války byla Pustoška 16. července 1941 obsazena německou armádou a 27. února 1944 dobyta zpět jednotkami 2. baltského frontu Rudé armády.

Odkazy

Reference

Externí odkazy

Města v Pskovské oblasti

redpajama_set_name: RedPajamaWikipedia


MARCH, Crappie are biting at the North (upper blue basin) in shallow water. Several boats reported catching nice size crappie, some 2 lbs or more. The shallower water cools down faster and the crappie and starting to feed.


Just before going out to buy or adopt a brand-new puppy dog or grown pet, have a little bit of time as well as make certain you are actually properly prepared. Offering good canine care is fairly a duty and there are several aspects to consider. Right here are actually 6 basic ideas developed to aid you obtain gotten ready for the brand new animal's landing.
All canines need lots of day-to-day exercise-- it is actually a big component of terrific pet dog treatment. With a toy canine multiply this is fairly easy to perform-- they normally acquire adequate exercise on a daily basis only walking from one end of our home to the other. However along with a medium to large sized pet it is actually a different account. They call for a decent-- sized fenced lawn or a daily walk everyday.
When heading to review a litter of young puppies Click Here are some general suggestions. Carefully review each of the pups. If any kind of one dog appears to be sick, after that that is actually most likely a good idea to look somewhere else-- over most likely the whole litter is sick.
A healthy and balanced young puppy or adult pet ought to possess brilliant and definite eyes-- with no indication of mucus or discharge. Their ears will certainly be clean and also devoid of bloodsuckers. They need to walk directly without any droopy. And also their coating will be actually without sores or bald patches. Be sure to request any kind of enrollment documents and also health and wellness files prior to taking on a pet.
Pets dogs are actually social animals as well as need tons of friendship to remain pleased as well as well-balanced. If you'll be gone with substantial periods during the day, you could wish to consider obtaining a second pet dog-- some of his young buddies or an additional compatible pet off the sanctuary. This is yet another example of really good pet treatment.
Dogs hunger for self-control and also construct in their lives to keep all of them delighted as well as healthy. So you should begin educating your pup or even canine quickly. As well as feel this or not, also a much older dog may be qualified. Lots of folks don't recognize that canine instruction is actually a big part of looking after pet dogs.
Whether you take lessons or get manuals as well as Videos to discover dog instruction, keep in mind that your dog will definitely certainly not become completely loyal through the night. That is actually a constant procedure and some canines advance faster in comparison to others. Yet if you're chronic as well as spend enough time and effort you'll ultimately have actually an entirely trained canine.
Aim to give your dog a top quality food designed for their certain stage of life. Quality food might be a little bit even more pricey compared to the general, cheap range-- yet you'll find yourself conserving money over time. Your canine will certainly be actually much healthier as well as won't require as a lot of excursions to the vet.
You must certainly never offer your pet dogs "people food" or "table disputes." It is undoubtedly an example of inadequate dog treatment. I understand this is actually tough to withstand a begging canine, however you're in fact being heartless when you give in. That causes all form of major health issue featuring joint inflammation and diabetes.
Faculty of Agricuture, P.O. Box 536, Egerton.


text:
namespace blink {

class CORE_EXPORT NGMathFractionLayoutAlgorithm
    : public NGLayoutAlgorithm<NGBlockNode,
                               NGBoxFragmentBuilder,
                               NGBlockBreakToken> {
 public:
  explicit NGMathFractionLayoutAlgorithm(const NGLayoutAlgorithmParams& params);

 private:
  scoped_refptr<const NGLayoutResult> Layout() final;

  MinMaxSizesResult ComputeMinMaxSizes(const MinMaxSizesInput&) const final;

  void GatherChildren(NGBlockNode* numerator, NGBlockNode* denominator);
  const NGBoxStrut border_scrollbar_padding_;
};

}  // namespace blink

#endif  // THIRD_PARTY_BLINK_RENDERER_CORE_LAYOUT_NG_MATHML_NG_MATH_FRACTION_LAYOUT_ALGORITHM_H_


text:
How To Build Credit with Stephen Liao
What they didn't teach you in school about building your credit line
In Bring Your Whole Self to Work, Mike Robbins pulls back the curtain
of the most effective teams on the planet. What do great leaders have in
common? What makes a team perform greater than its individual parts
would suggest? How do you solve problems before they arise? In short,
there are five key components that answer all these questions and more. To
bring our whole selves to work and therefore thrive, we must: be authentic,
utilize the power of appreciation, focus on emotional intelligence, embrace a
growth mindset, and create a championship team.
After dropping out of Stanford University, Stephen Liao knew he had to find a way to make money... somehow. His mind recalled a time when his father told him NEVER to get a credit card. So he looked into credit cards. A few years later, he's the proud owner of more than 200 cards and a credit line in the millions of dollars. He has developed an unmatched knowledge of credit systems, including how to boost your score and gain access to the most coveted cards out there.
How To Build Credit Overview (7:05)
What is Credit? (5:35)
Your Credit Score (5:42)
Essential Credit Factors (13:50)
FICO vs. Vantage (10:13)
Your Credit Journey (ESSENTIAL) (20:16)
Get Started (1:01)


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Wireless mesh networks (WMN) are a promising technology to establish big wireless networks with little costs. What we need are security mechanisms that perform well in this special kind of network. Therefore we propose the application of group key agreement (GKA) protocols, since a common encryption key in the network will remove the need for reencryptions and enables a better performance.
In this paper, we contribute a new theoretic approach to measure the performance of cryptographic protocols in WMN. We demonstrate the applicability of the new approach with three selected GKA protocols that have already been investigated regarding their WMN performance in previous work.


Mr.Baker was established in Bangladesh in the early 2001, with the help of a leading manufacturer of confectionery and bakery products in Belgium, whose ready made mixes and ideas were used by Mr.Baker. Right from the inception of Mr.Baker, the policy of the company has been very simple and consistent, of delivering high quality products and maintaining them. Using high quality raw material and frequent visits by international chefs from Europe does this. Mr. Baker is one of the top brand in Dhaka with 19 branches and all cakes are available for same day and urgent delivery.We include a free candle set with each cake gift delivery in Bangladesh.


charmarama Item was exactly as described, still in unopened box. Seller was very accommodating to change in collection time. Easy transaction.
vanhan Really patient during discussion of meetup and overall a really smooth experience!
100% brand new/sealed & authentic, directly imported from USA. SNACK 'N STACK Utensils is sized for kids and grown-ups alike. The silicone handles lock together securely for easy storage and packing, not to mention endless amusement. Perfect for lunch boxes, picnics, your desk drawer, or glove box!
100% brand new/sealed & authentic, directly imported from USA. NEAT EATS aren't your garden-variety cupcake moulds. Each charming silicone pot comes with an adorable flower fork that you can plant right into the cupcake. Your little crop of sprouts will love these easy-to-serve, easy-to-eat treats.


text:
using System;
using System.Threading;
using System.Reflection;
using System.Reflection.Emit;
using Xunit;
using System.Linq;

namespace System.Reflection.Emit.Tests
{
    [AttributeUsage(AttributeTargets.All, AllowMultiple = false)]
    public class CBMyAttribute2 : Attribute
    {
        public int m_i;

        public CBMyAttribute2(int i)
        {
            m_i = i;
        }
    }

    public class ConstructorBuilderSetCustomAttribute2
    {
        [Fact]
        public void TestSetCustomAttribute()
        {
            AssemblyName myAssemblyName = new AssemblyName("EmittedAssembly");
            AssemblyBuilder myAssembly = AssemblyBuilder.DefineDynamicAssembly(myAssemblyName, AssemblyBuilderAccess.Run);
            ModuleBuilder myModuleBuilder = TestLibrary.Utilities.GetModuleBuilder(myAssembly, "Module1");
            TypeBuilder myTypeBuilder = myModuleBuilder.DefineType("HelloWorld", TypeAttributes.Public);
            ConstructorBuilder myConstructor = myTypeBuilder.DefineConstructor(
                     MethodAttributes.Public, CallingConventions.Standard, new Type[] { });
            ILGenerator myILGenerator = myConstructor.GetILGenerator();
            myILGenerator.Emit(OpCodes.Ldarg_1);

            ConstructorInfo myConstructorInfo = typeof(CBMyAttribute2).GetConstructor(new Type[1] { typeof(int) });
            CustomAttributeBuilder attributeBuilder =
               new CustomAttributeBuilder(myConstructorInfo, new object[1] { 2 });

            myConstructor.SetCustomAttribute(attributeBuilder);
            Type myHelloworld = myTypeBuilder.CreateTypeInfo().AsType();

            ConstructorInfo myReflectConstructorInfo = myHelloworld.GetConstructor(new Type[] { });
            object[] CBMyAttribute2s = myReflectConstructorInfo.GetCustomAttributes(true).Select(a => (object)a).ToArray();

            Assert.Equal(1, CBMyAttribute2s.Length);
            Assert.Equal(2, ((CBMyAttribute2)CBMyAttribute2s[0]).m_i);
        }

        [Fact]
        public void TestThrowsExceptionOnNullCustomAttributeBuilder()
        {
            AssemblyName myAssemblyName = new AssemblyName("EmittedAssembly");
            AssemblyBuilder myAssembly = AssemblyBuilder.DefineDynamicAssembly(myAssemblyName, AssemblyBuilderAccess.Run);
            ModuleBuilder myModuleBuilder = TestLibrary.Utilities.GetModuleBuilder(myAssembly, "Module1");

            TypeBuilder myTypeBuilder = myModuleBuilder.DefineType("HelloWorld", TypeAttributes.Public);
            ConstructorBuilder myConstructor = myTypeBuilder.DefineConstructor(
                     MethodAttributes.Public, CallingConventions.Standard, new Type[] { });
            ILGenerator myILGenerator = myConstructor.GetILGenerator();
            myILGenerator.Emit(OpCodes.Ldarg_1);
            Assert.Throws<ArgumentNullException>(() => { myConstructor.SetCustomAttribute(null); });
        }
    }
}