The plates were yellow and orange, amid the green foliage and blue water of the pool. The napkins and forks were tied together, purple plastic inside grass green paper and the pary was ready to go. Except no one remembered to check the forecast.
Baekhyun walked around aimlessly. It seems that everyone was having a fun time at the celebration of their 12th win for 'Growl' and he wanted to join in but he was too busy looking for a very important giant.
Festive….parties, holidays, getting dressed and dolled up and caught up in the spirit of celebration…grand gowns and fancy dress and mannerisms of times past. Feeling giddy and excited as the collective emotions excite every neuron; diffusing through every fiber of your being…..the party; the festivities….await.
I feel best during the holidays. I don't know if it's the good feeling that people inevitably have during the holidays, or if I just like eating holiday food. Either way, I'm my best self from October 31st to January 1st.
It is a festive season. Everybody is celebrating. They are reveling in debt, in the misery and poverty of life. They are celebrating attachment and emotional cost. And yet, I'm not sure if they are enjoying the festivities, because if they did, they would seek more consciously. And I don't think they are.
As fall fades to winter, the colours fade from bright red to a dull yellow. Childhood innocence is lost with the excitement of life.
The mood swells. The air is deep, and your heart moves. It is a feeling. A community.
Hand in hand with the soul you want to meet.
A celebration of everything in between.
I was in a festive mood after landing in Trinidad, and I went to one of the many dance hall clubs that play good music. I had a good time wining and dining up until ten in the night.
The time had come to start with the planning and the making and the writing of sweet DIY tutorials on the blog. Of course, the tutorials can't be published lest someone see their gift early…but they could lie in wait. When did writing crafting tutorials become a part of the festive season?
I feel less than festive at the moment. It is difficult when you're the one who's depended on to make festive plans and then do all the preparation for the festivities, while everyone else sits back and simply waits to enjoy. One day, I swear, I'll let someone else do all the planning.
The air was alive with music. Soul lifting, corner of lip raising, booty shaking music. My eyes lit up with the reflection of fireworks of every color. The sky was dazzling in it's fog covered spectrum of multi-colored phantasm.
My first festival was a non-sensical blur of my deepest inhibitions being released.
I love the festive season. Christmas is a wonderful family occasion when we can get together and not feel guilty about eating too much!
This is the day. This is the day I've always dreamed of as a little girl. I hold on to my puffy champagne gown as I've always imagined it would be. I feel like a princess. I feel beautiful, not pretty. I feel loving, and loved. I close my eyes and breathe; open them as the doors open as well. As I walk, I feel everything at once. I wanna laugh. I wanna cry. I wanna run towards your arms.
The world is a carnival. We have our celebrations and our rituals, loss and truth. Love hurts no truth. We belong to the celebration of love and longing.
The setup for the party was almost done. Martin looked around at his brightly coloured decorations, and smiled, because he knew this Halloween was going to be remembered. By everyone. Including Marcey. Including Joanne. Including Steve. They thought they could get away with laughing at his designs. At his beautiful creations. Something that improved upon humanity.
Marty had planned on having the last laugh.
And his plans ALWAYS came to pass.
I think fall is a festive time of year because in this season we have Halloween and thanksgiving.
Its snowing, in my dreams. Theres White Christmas on the TV and I am a child again. I can never go home now, return to that place and time. Today it is late, in the year and the years of my life. I wonder how my daughter will recall these days.
I love colorful clothes – scarves, hats, embroidered blouses – they make me feel so festive. Sequins are always good for a party, too.
She was in a festive mood. I was at the opposite end of the emotional spectrum.
This was our second date and already I felt it wasnt working. The first was fun but there was an over the top feeling about her which crowded me out and took over.
This was so in your face I thought – the sparkling lights.
I don't feel festive. Yesterday I did not feel festive. I will not feel festive for quite some time now, but I have to put on a smile and pretend like nothing is wrong, because if I do, well, that just defeats the purpose now, doesn't it?
Fun, family, food, enjoyment. Happy memories! Festivals are the best time of the year.


Sean Gill is asked about the inspiration for his short story, "In the Cutting Room"
Sean Gill is asked about the inspiration for his short story, "For Want of a Better Word"
Sean Gill is interviewed by Cleaver Magazine about his play, "Dreams of the Clockmaker"
Sean Gill is interviewed by Adam Szymkowicz about his play, "Dreams of the Clockmaker"
Sean Gill is interviewed by Byrne Harrison about his play, "Dreams of the Clockmaker."
Sean Gill is interviewed by Byrne Harrison about his play, "Laurie Deacon & the Night Caller"
Sean Gill is interviewed by The Happiest Medium about his play, "Laurie Deacon & the Night Caller"
Sean Gill is interviewed by Tom Murrin about his play, "Go-Go Killers!"
Sean Gill is interviewed by Heidi Patalano about his play, "Go-Go Killers!"
Sean Gill is interviewed by United Stages about his play, "Go-Go Killers!"


text:
Q: Bundler ignoring 'without' group I'm trying to include gems from my local instead of the gemserver on development. My Gemfile looks like this:
group :development do
  gem "appy_core", path: "../engines/core"
end

group :production do
  gem "appy_core", '1.7.4.5'
end

My .bundle/config is set to:
---
BUNDLE_WITHOUT: production

Yet when I run bundle I get:
 [!] There was an error parsing `Gemfile`: You cannot specify the same gem twice with different version requirements.
 You specified: appy_core (>= 0) and appy_core (= 1.7.4.5). Bundler cannot continue.

Running bundle install --without production produces the same result.

A: The only solution I came up with / am aware of:
in Gemfile:
gem 'appy_core',
    git: 'git://github.com/.......',
    branch: '1.7.4.5' # put the name of the branch that corresponds

in local environment's shell:
$ bundle config local.appy_core /path/to/engines/core

Now do whatever you want in the local branch, commit it locally and enjoy.

Hack that works
Since Gemfile is plain ruby, one might use ruby features there:
somewhere in permanent shell settings:
alias bundle="USE_DEV_VERSION=1 bundle"

in Gemfile:
if ENV['USE_DEV_VERSION']
  gem "appy_core", path: "../engines/core"
else
  gem "appy_core", '1.7.4.5'
end

Now bundle install will use dev version locally and the standard gem outside of the "patched" environment.

A: Since Gemfile is executed as Ruby code, you can reference Bundler.settings directly to explicitly exclude duplicate gems within a group:
def without?(group)
  Bundler.settings.without.include?(group)
end

group :development do
  gem "appy_core", path: "../engines/core" unless without? :development
end

group :production do
  gem "appy_core", '1.7.4.5' unless without? :production
end

redpajama_set_name: RedPajamaStackExchange


text:
› Coronavirus Patient First Admitted to Intensive Care Leaves Hospital
Coronavirus Patient First Admitted to Intensive Care Leaves Hospital
Scott Howell left his hospital ward earlier to be reunited with his wife and four children at home after spending eight weeks in hospital. He was in a coma for two-and-a-half weeks and was saved by clinicians on two occasions when his heart stopped. After leaving intensive care, within two weeks of being bed-bound, he was helped by the hospital's rehabilitation staff to climb a flight of stairs.
Scott, aged 48, from Blackwood, said: "The staff here saved my life – they put their own lives on the line and I'm so grateful for what they've done for me and others.
"The care I've received has allowed me to be a husband and father again and it's wonderful! As much as I appreciate the professional excellence of the staff at the Royal Gwent, it's fantastic to be able to leave.
"Every member of staff I encountered in the hospital including porters, cleaners, physios, doctors and nurses were amazing. The NHS services we have here are as good as any in the world."
Scott explained how pleased he was to be reunited with his family at home. "It was unbelievably fantastic to be in the fresh air and to see my family," he said. My wife hasn't slept since I was admitted to hospital. The staff helped us to video call each other from my hospital bed so she could see my progress, but to have a hug from my wife and children when I left hospital was fantastic. They had decorated the house ready for my return which made it extra special for me."
Intensive Care Consultant Dr Dave Hepburn said: "Scott was as ill as anybody can be, so to see him leaving hospital has been a massive lift for staff across the Health Board.
"All the hardship and pressure we are facing at the moment is all worth it when you see people like Scott get better and reunited with their families - it's the best gift we can receive."
Thank you to Dr Nick Mason for the photographs of Scott.

redpajama_set_name: RedPajamaCommonCrawl


Welcome to the number one website with the best, most accurate New Moon days to trim your hair. You will find dates elsewhere, but these dates are the best ones, so click no further. Before you read any further, locate the box in the right hand column and subscribe so you can receive other New Moon trims dates, for increased hair growth.
You should trim your hair every 4th month, this equals three times per year. Trimming your ends keeps your hair looking thicker and healthier. It decreases tangles and makes styling much easier. Since you need to trim 3 times per year why not schedule your trims on the best days which increase your hair growth.
What is the New Moon hair growth method? This is when you choose certain days within the month to trim your hair or start a hair treatment, to double your normal hair growth rate. You schedule your hair trims on specific days according to the lunar calendar, when the energy of the moon is the strongest. I have been trimming my hair according to the lunar calendar for almost a year and I have received the best hair growth ever.
During the Month of May we celebrate Mother's, treat your mother to a trim on one of the above days, or even better give a her a trim yourself. Help mom start her healthy hair journey. Maybe she needs to big chop and start her natural hair journey.
Hi Miss Vee, Which is the 'best' date for trimming in May?
The 13th or the 14th has the highest energy this month.
Okay I will do that thanks.
June n July dates please?


Colorado State University (CSU) will be expanding its product design instruction previously given primarily to engineering students out to the broader community. The university is launching a new certification program that will use resources provided by PTC, a company that works with manufacturers to improve their design, production and service processes.
The Fort Collins institution already uses the company's product design software with undergraduate mechanical engineering students. Now it has become a PTC "Authorized Training Partner." That designation will allow the university and its faculty to train people who want continuing education and professional development alternatives. The training will focus on PTC's computer-aided design suite, Creo, and Windchill, the company's collaboration software.
For example, this month the school will offer a $1,500 three-day class on Creo. The first day will cover the basics, the second day intermediate usage, and the third day advanced techniques. The initial projections expect the university to run eight to 10 courses each year if they prove of interest.
"With our state-of-the-art facility, links to industry and specially equipped engineering computer labs, becoming a PTC Authorized Training Partner in order to expand the curriculum and technology into the community was a natural fit," said Patrick Burns, dean of libraries and vice president for IT.
Added Adjunct Faculty member Barry Brinks, "The training program CSU offers with PTC is unique. For the first time we are showing not just the basics of how PTC Creo CAD software can be utilized, but also blending it with exciting new technologies such as additive manufacturing and 3D scanning to create a unique learning experience for PTC customers and students at the university."
Those who complete the coursework will receive a certificate of completion from Colorado State.


text:
Q: Help me change this JS/Jquery Function to Dynamically Create Divs I have uploaded my code to JSfiddle:
http://jsfiddle.net/TSM_mac/pnQEe/
I want to be able to type into the text inputs on the page, and click the "Add Div Type" button, and it will append (create) the div element inside of the div you click on (that has the class = "editable").
I have having difficulty making this code work. Can anyone find where I went awry?
Code
var $currentInput = null;

$("#add_div1, #add_div2, #add_div3").click(function() {
    $currentInput = null;
    if ($currentInput == null) {
        $currentInput = $(this).prev();
        $("label").html($currentInput.attr("id"));
    }
});

var editid;
$("div.editable").click(function(e) {
    e.stopPropagation();
    if ($currentInput == null) return;
    editid = $(this).attr("id");
    var adddiv = GetElements();
    $(this).append(adddiv);
    $("label").html("");
});

function GetElements() {
    if ($currentInput == null) return null;

    var value = $currentInput.val();

    if ($currentInput.attr("id") == "add_div1") return {
        "
"+value+"
"
    }
    if ($currentInput.attr("id") == "add_div2") return {
        "
"+value+"
"
    }
    if ($currentInput.attr("id") == "add_div3") return {
        "
"+value+"
"
    }
}

-
<input type="text" id="add-div1" value="Content of Div 1" />

Add Div Type 1

<input type="text" id="add-div1" value="Content of Div 2" />

Add Div Type 2

<input type="text" id="add-div1" value="Content of Div 3" />

Add Div Type 3

    Add a Div Here

     Add a Div Here

    Add a Div Here

-
input { display: block; padding-top: 10px; }
#add_div1, #add_div2, #add_div3 { background: #c0c0c0; border: solid 1px #777; display: inline-block; }

.editable { border: solid 5px green; margin: 20px; background: blue; color: #fff; }

Regards,
Taylor

A: this one works now
http://jsfiddle.net/pnQEe/5/
(I added some console.log but now is commented out)
seems like your code is that you need to click the button and then click the div
Issue #1:  you have   return {  ...  }   It should be { return ... } or just return ...
Issue #2: you have add-div1 but the code checked against add_div1 (underscore, not hyphen)
Also, I try not to have two elements with the same or similar id name as well. (such as add-div1 for the text input, and add_div1 for the button -- looks too similar.


text:
August 2013, VOLUME 132 / ISSUE 2
Neonatal Infection and 5-year Neurodevelopmental Outcome of Very Preterm Infants
Ayoub Mitha, Laurence Foix-L'Hélias, Catherine Arnaud, Stéphane Marret, Rachel Vieux, Yannick Aujard, Gérard Thiriez, Béatrice Larroque, Gilles Cambonie, Antoine Burguet, Pascal Boileau, Jean Christophe Rozé, Monique Kaminski, Patrick Truffert, Pierre-Yves Ancel for the EPIPAGE Study Group
OBJECTIVE: To determine whether neonatal infections are associated with a higher risk of adverse neurodevelopment at 5 years of age in a population-based cohort of very preterm children.
METHODS: We included all live births between 22 and 32 weeks of gestation, from 9 regions in France, in 1997 (EPIPAGE study). Of the 2665 live births, 2277 were eligible for a follow-up evaluation at 5 years of age: 1769 had a medical examination and 1495 underwent cognitive assessment. Cerebral palsy and cognitive impairment were studied as a function of early-onset sepsis (EOS) and late-onset sepsis (LOS), after adjustment for potential confounding factors, in multivariate logistic regression models.
RESULTS: A total of 139 (5%) of the 2665 live births included in the study presented with EOS alone (without associated LOS), 752 (28%) had LOS alone (without associated EOS), and 64 (2%) displayed both EOS and LOS. At 5 years of age, the frequency of cerebral palsy was 9% (157 of 1769) and that of cognitive impairment was 12% (177 of 1495). The frequency of cerebral palsy was higher in infants with isolated EOS (odds ratio [OR]: 1.70 [95% confidence interval (CI): 0.84−3.45]) or isolated LOS (OR: 1.71 [95% CI: 1.14−2.56]) than in uninfected infants, and this risk was even higher in cases of combined EOS and LOS (OR: 2.33 [95% CI: 1.02−5.33]). There was no association between neonatal infection and cognitive impairment.
CONCLUSIONS: Neonatal infections in these very preterm infants were associated with a higher risk of cerebral palsy at the age of 5 years, particularly in infants presenting with both EOS and LOS.
cohort study
neonatal infection
neurodevelopmental outcome
population-based study
very preterm infants
CI —
EOS —
early-onset sepsis
EPIPAGE —
Etude Epidémiologique sur les Petits Ages Gestationnels
K-ABC —
Kaufman Assessment Battery for Children
LOS —
late-onset sepsis
MPC —
mental processing composite Scale
What's Known on This Subject:
Neonatal infections are frequent complications in very preterm infants, already at high risk of neurologic and cognitive disabilities. Few studies have linked neonatal infections and neurodevelopmental outcomes. Those that did evaluated children only to the age of 22 months.
What This Study Adds:
This study assessed the respective effects of early- and late-onset sepsis and their association with 5-year neurodevelopmental outcomes. We identified a significant and cumulative risk of cerebral palsy when episodes of early- and late-onset sepsis were associated.
Very preterm infants have a high risk of neurodevelopmental impairment, including cognitive and psychomotor delay.1 Cerebral palsy, the most common and severe motor sequela, occurs in ∼80 to 90 per 1000 very preterm births.1–3 Cerebral white matter damage, identified principally by using magnetic resonance imaging but also by cranial ultrasound scans, is a powerful predictor of cerebral palsy in very preterm infants.4–6 Recent studies have identified perinatal infection and inflammation as risk factors for cerebral white matter damage.7–10 Preterm infants born to mothers with clinical or histologic chorioamnionitis are at risk for adverse neurodevelopmental outcomes, with a particularly high risk of cerebral palsy.11
Very preterm infants have a high risk of multiple infections between birth and hospital discharge. More than 50% of extremely low birth weight infants (<1000 g) are treated for clinical or proven neonatal infection during their hospitalization,12 and the associated mortality is high (20%–40%).13–15 Follow-up studies of preterm infants have suggested an association between inflammation, cerebral white matter damage, and cerebral palsy,16–19 but very few studies have directly addressed the possible links between neonatal infections and neurodevelopmental outcomes.8,20 The objective of the current study was to evaluate the impact of neonatal infections on 5-year neurodevelopmental outcomes in a large population-based cohort of very preterm infants.
EPIPAGE (Etude Epidémiologique sur les Petits Ages Gestationnels) is a population-based cohort study in which children were followed up from birth to 5 years of age.21 This study included all live births between 22 and 32 completed weeks of gestation in all the maternity units of 9 French regions (more than one-third of the regions in the country) from January 1, 1997, to December 31, 1997. Overall, 127 (4%) of the 2901 live-born children recorded died in the delivery room, and information about neonatal infection was missing for another 109 infants; these children were all excluded (Fig 1). Thus, 2665 live births were included in the study. There were 291 neonatal deaths during hospitalization, leaving 2374 infants who were discharged from the hospital alive. Follow-up was proposed at hospital discharge for all the surviving infants in 7 of 9 regions. In the remaining 2 regions, follow-up was proposed for one-half the infants born at exactly 32 weeks of gestation, selected at random. The population included in this follow-up study therefore consisted of 2302 very preterm infants, 25 of whom died before the age of 5 years, leaving a total of 2277 survivors for follow-up at 5 years.
The study group. MPC of the Kaufman Assessment Battery for Children was used for analysis. GA, gestational age.
The study was approved by the French data protection agency (Commission Nationale de l'Informatique et des Libertés). The parents received written information about the study and provided oral consent for participation.22
Neonatal Infections
The data concerning neonatal infection were collected from neonatal records by using a standardized questionnaire. Two types of infection were studied: infections of maternal (ie, vertically transmitted) origin and postnatally (ie, horizontally) acquired infections. For infections of maternal origin, each child was classified as having no infection, confirmed infection, probable infection, or colonization. Early-onset sepsis (EOS) was defined as confirmed infection of maternal origin (vertically transmitted), on the basis of medical records. Late-onset sepsis (LOS) was defined as a postnatally acquired infection (horizontally acquired) treated with antibiotics for at least 7 days, also on the basis of medical records.
Maternal and Neonatal Data
Data for mothers, pregnancy, birth, and neonatal outcomes were recorded on standardized questionnaires at each maternity unit. Maternal data included antenatal corticosteroid therapy, premature rupture of membranes, maternal hemorrhage, spontaneous preterm labor, and type of pregnancy (singleton or multiple). Neonatal data included gender, gestational age (determined from the last menstrual period and findings from early prenatal ultrasound scans, calculated in completed weeks), small for gestational age (defined as a birth weight less than the 10th percentile for gender and gestational age in the EPIPAGE population), duration of central venous line use, and cranial ultrasound abnormalities. Cranial ultrasound scans were routinely performed during the neonatal period, and abnormalities were classified as major or moderate lesions in cases of periventricular leukomalacia or periventricular parenchymal hemorrhage, intraventricular hemorrhage with ventricular dilation or isolated ventricular dilation, or echodensity lasting >14 days. They were classified as minor lesions when intraventricular hemorrhage without ventricular dilation or germinal matrix layer hemorrhage was reported.6
Neurodevelopmental Outcomes
At 5 years of age, a complete medical and neuropsychological assessment was performed by trained physicians and psychologists at centers specifically set up for the study in each region. A medical questionnaire was completed by the physician after the clinical assessment, which included a standardized neurologic examination (tone, reflexes, posture, and movements). We used the definition of cerebral palsy established by the European Cerebral Palsy Network,23 which requires the presence of at least 2 of the following: abnormal posture or movement, increased tone, and hyperreflexia. Cerebral palsy status was known for 1769 very preterm children (78% of the children who survived to follow-up at 5 years of age).
The Kaufman Assessment Battery for Children24 was used to assess cognitive function, expressed as a mental processing composite (MPC) score, which is an IQ equivalent. The MPC score provides a global measurement of cognitive ability, standardized to a mean ± SD of 100 ± 15.24 MPC scores <70 indicate severe cognitive impairment.1 Children who did not complete all of the tests in the battery were not included in the analysis of cognitive impairment. Cognitive scores (MPC) were available for 1495 (66%) children who survived to follow-up at 5 years of age.
We first studied the associations between maternal and neonatal characteristics, and then neonatal infections and neurologic outcomes (cerebral palsy and MPC score). The goal was to identify potential confounders in the relationship between neonatal infections and neurologic outcomes. Early- and late-onset neonatal infections were studied independently (EOS, yes/no; LOS, yes/no) and together. We used a combined indicator to assess the respective effects of EOS and LOS and their association. Infants were classified as follows: uninfected, EOS alone (no associated LOS), LOS alone (no associated EOS), or both EOS and LOS.
The associations between neonatal infections and neurologic outcomes (cerebral palsy and MPC score) were studied by using logistic regression models, which were constructed separately for each outcome. For cerebral palsy, models were adjusted for maternal and neonatal variables selected in the univariate analysis (preterm rupture of membranes, spontaneous preterm labor, gender, gestational age, and small for gestational age) and other factors previously reported to be associated with short- and long-term outcomes (eg, antenatal corticosteroid therapy). For cognitive impairment, models were adjusted for maternal and neonatal variables selected in the univariate analysis (maternal age at birth, maternal level of education, parity, preterm rupture of membranes, gender, gestational age, small for gestational age, and duration of central venous catheter use) and other factors previously reported to be associated with short- and long-term outcomes (eg, antenatal corticosteroid therapy).
Associations were quantified according to odds ratios (ORs) and 95% confidence intervals (CIs). Analyses of MPC scores <70 were repeated after the exclusion of children with cerebral palsy. Weights were used to take into account the differences in the proportion of children born at 32 weeks included in the different regions. Only weighted percentages are presented in the tables. Data from infants who were alive but did not complete their follow-up were compared with data from those who completed follow-up. All statistical tests were 2-tailed, with P < .05 regarded as significant. Stata version 11.0 software (Stata Corp, College Station, TX) was used for analysis.
Of the 2665 very preterm children born alive, 203 (8%) had EOS, which was not associated with LOS in 139 (5%); 816 (31%) had LOS, which was not associated with EOS in 752 (28%); and 64 (2%) had both EOS and LOS. Bacteriologic results were known in 84% (171 of 203) of EOS cases and 75% (614 of 816) of LOS cases. The most frequently detected organisms were group B Streptococcus (34%) and Escherichia coli (33%) for EOS and coagulase-negative Staphylococcus (46%) and Staphylococcus aureus (20%) for LOS.
For cerebral status and cognitive assessment, infants who were alive but did not complete their follow-up visit had a slightly higher gestational age and a lower maternal level of education than those who did complete follow-up. There were no differences in terms of infections (EOS and LOS), antenatal corticosteroid therapy, gender, small for gestational age, or cerebral lesions (Table 1).
Characteristics of Survivors Seen at the Follow-up Visit at 5 Years and Infants Alive But Lost to Follow-up
Maternal and neonatal characteristics differed between the EOS and LOS groups (Table 2). EOS was more frequent in cases of premature membrane rupture. LOS was significantly more frequent in children who were small for gestational age. Rates of EOS and LOS infections increased with decreasing gestational age.
EOS and LOS as a Function of Maternal, Pregnancy, and Neonatal Characteristics
Cerebral palsy was found in 157 (9%) of the 1769 infants with known cerebral status, and 177 (12%) of the 1495 infants for whom a cognitive score (MPC) was available were found to have severe cognitive impairment. Maternal and neonatal characteristics differed as a function of neurologic outcome (cerebral palsy and MPC score) (Table 3). Cerebral palsy was significantly more frequent in cases of spontaneous preterm labor and in male infants. Severe cognitive impairment was significantly more frequent in cases of low maternal level of education and in children born to multiparous mothers. The frequencies of cerebral palsy and severe cognitive impairment increased with decreasing gestational age.
Cerebral Palsy and Cognitive Impairment (MPC <70) as a Function of Maternal, Pregnancy, and Neonatal Characteristics
The risk of cerebral palsy was higher in children with EOS or LOS than in uninfected children, but these associations were no longer significant after adjustment for potential confounders (Table 4). However, if both EOS and LOS were considered (Table 5), children with isolated LOS or associated EOS and LOS had a higher risk of cerebral palsy than uninfected children. These associations remained significant after adjustment. There was no association between neonatal infection and severe cognitive impairment before or after adjustment (Table 6).
Relationship Between Cerebral Palsy, EOS (yes/no), and LOS (yes/no)
Relationship Between Cerebral Palsy and Neonatal Infection (Uninfected Versus Infected)
Relationship Between Severe Cognitive Impairment (MPC<70), EOS, and LOS (After the Exclusion of Children With Cerebral Palsy)
We found that neonatal infections in these very preterm infants were associated with a higher risk of cerebral palsy at 5 years of age, particularly when both EOS and LOS were present. There was no association between neonatal infection and cognitive impairment.
Our study was based on data from the EPIPAGE cohort, one of the largest population-based studies of very preterm infants, with an accurate assessment of the gestational age of all very preterm children. In France, early ultrasound assessments of gestational age are routinely conducted, and gestational age determination according to this method is considered highly satisfactory.25 Children enrolled in the EPIPAGE study were evaluated at the age of 5 years, with standardized, validated criteria, for the detection of cerebral palsy and cognitive impairment.23,24
Loss to follow-up is a common issue in longitudinal studies and may bias the results. However, medical data were available at 5 years for more than three-quarters of the very preterm children, and an MPC score was available for almost two-thirds of these children. This follow-up rate should be viewed in light of the large number of children investigated, their geographic dispersion, and the frequent movement of parents with young children. Moreover, our follow-up rate is similar to that of other population-based studies.26,27 However, studies in which complementary investigations are conducted for children who were initially lost to follow-up have reported worse outcomes for these children.28 This finding may have led to an underestimation of cognitive impairment, because loss to follow-up was more common in socially disadvantaged children, and these children have a higher risk of lower cognitive scores. Children lost to follow-up had a slightly higher gestational age at birth than did those remaining in the study, but neonatal cerebral lesions and neonatal infections did not differ between the 2 groups. Thus, any bias in our assessment of the prevalence of cerebral palsy is probably small.
Our study is the first to focus on the association between neonatal infections and 5-year neurodevelopmental outcomes in very preterm children. Children presenting with both EOS and LOS had a higher risk of cerebral palsy than uninfected children. Moreover, children with isolated LOS also had a higher risk of cerebral palsy than uninfected children. The association with isolated EOS was no longer significant after adjustment, but we cannot exclude the possibility that this finding was due to a lack of statistical power. Very few studies have directly investigated the potential links between neonatal infection and neurodevelopmental outcome.8,20 Stoll et al8 conducted a large cohort study of 6093 extremely low birth weight infants (from the Eunice Kennedy Shriver National Institute of Child Health and Human Development) comparing uninfected infants with those presenting with isolated clinical infection, sepsis, sepsis and necrotizing enterocolitis, or meningitis (with or without sepsis). They found that infants with infections of these types were significantly more likely to have adverse neurodevelopmental outcomes at follow-up visits at 18 to 22 months of corrected gestational age, including cerebral palsy (range of significant OR: 1.4–1.7), low mental development index (OR: 1.3–1.6), and psychomotor development index (OR: 1.5–2.4) on the Bayley Scales. In a more recent Swiss national cohort of 541 extremely premature infants born at gestational ages of 24 to 27 weeks,20 proven sepsis per se increased the risk of cerebral palsy (OR: 3.23 [95% CI: 1.23–8.48]) at a corrected age of 2 years. In both studies,8,20 neurodevelopmental status was assessed in early childhood, an approach that is known to be less strongly predictive than the later assessment of long-term neurodevelopmental outcome.29
We studied very severe cognitive impairment (MPC score <70), potentially accounting for the lack of association between neonatal infections and cognitive impairment. However, the mechanisms underlying cognitive impairment are more complex, probably involving a combination of brain damage, persistent inflammation, and epigenetic changes resulting in the impairment of brain maturation and development.30 Studies in a number of experimental animal models have suggested that there is a relationship between cytokine responses, hypotension, and white matter injury.31–33 Studies in premature infants have also shown a relationship between inflammatory cytokine levels and white matter injury,34,35 which is known to be associated with cerebral palsy.4,6 Glass et al36 found that exposure to multiple episodes of culture-positive infection increased the risk of progressive white matter injury. Another recent study, by Chau et al,37 provides further evidence that postnatal infection, even in the absence of positive culture results, is an important risk factor for widespread abnormalities of brain development in premature infants.
The frequency of EOS differs considerably between studies, depending on the population considered; published values range between 1% and 15%. The high frequency of EOS (8%) in our study may be accounted for by the use of a diagnostic procedure less specific than the criteria used in previously published studies. The frequency of LOS was 31% in the 2665 very preterm infants included in our study, a rate consistent with published data (21%–66%),12,38,39 even though the diagnosis of neonatal infection was not based on highly specific criteria (ie, a positive blood culture result or 2 positive culture results for coagulase-negative staphylococcal infections).40 The diagnosis of a bloodstream infection in adults is based on a single positive result on blood culture, but this criterion cannot be transposed directly to newborn children in general and to preterm infants in particular. Indeed, the mean volume of blood dispensed into blood culture bottles for preterm infants is <0.5 mL,41,42 greatly limiting the discrimination possible with this test. This limitation may lead to errors in the diagnosis of infections, due to misclassification (false-positive and false-negative results). These misclassifications are independent of neurodevelopmental outcome but are likely to result in a lack of power in studies of associations between neonatal infections and long-term outcomes.
The originality of the current study resides in the use of an indicator combining the 2 types of neonatal infections in relation to cerebral palsy and cognitive impairment at 5 years of age. The higher risk of cerebral palsy in cases of neonatal infection is consistent with the neurotoxic effects of infectious and inflammatory mediators on cerebral white matter, particularly in children suffering both early- and late-onset infections. The development of appropriate strategies for reducing infection rates would thus help to improve the neurodevelopment outcomes of these vulnerable infants. The evaluation of such strategies should be validated in randomized trials.
The composition of the EPIPAGE Study Group was as follows: INSERM U953: B. Larroque (national coordinator), P.Y. Ancel, B. Blondel, G. Bréart, M. Dehan, M. Garel, M. Kaminski, F. Maillard, C. du Mazaubrun, P. Missy, F. Sehili, K. Supernant, and L. Marchand; Alsace: M. Durant, J. Matis, J. Messer, and A. Treisser (Hôpital de Hautepierre, Strasbourg); Franche-Comté: A. Burguet, L. Abraham-Lerat, A. Menget, P. Roth, J.-P. Schaal, and G. Thiriez (CHU St Jacques, Besançon); Haute-Normandie: C. Lévêque, S. Marret, and L. Marpeau (Hôpital Charles Nicolle, Rouen); Languedoc-Roussillon: P. Boulot and J.-C. Picaud (Hôpital Arnaud de Villeneuve, Montpellier), A.-M. Donadio, and B. Ledésert (ORS Montpellier); Lorraine: M. André, J. Fresson, and J.M. Hascoët (Maternité Régionale, Nancy); Midi-Pyrénées: C. Arnaud, S. Bourdet-Loubère, and H. Grandjean (INSERM U558, Toulouse), M. Rolland (Hôpital des enfants, Toulouse); Nord-Pas-de-Calais: C. Leignel, P. Lequien, V. Pierrat, F. Puech, D. Subtil, and P. Truffert (Hôpital Jeanne de Flandre, Lille); Pays de la Loire: G. Boog, V. Rouger-Bureau, and J.-C. Rozé (Hôpital Mère Enfants, Nantes); and Paris-Petite-Couronne: P.-Y. Ancel, G. Bréart, M. Kaminski, and C. du Mazaubrun (INSERM U953, Paris), M. Dehan and V. Zupan-Simunek (Hôpital Antoine Béclère, Clamart), and M. Vodovar, M. Voyer (Institut de Puériculture, Paris).
We are indebted to the women and children who participated in the study. We are grateful to all the members of the EPIPAGE group, including the study designers and investigators.
Address correspondence to Ayoub Mitha, MD, Epidemiological Research Unit on Perinatal and Women's Health, INSERM U953, Bâtiment de Recherche RDC Hôpital Tenon, 4 rue de la Chine, 75020 Paris, France. E-mail: ayoub.mitha{at}yahoo.fr
Dr Mitha conceptualized and designed the study, drafted the initial manuscript, carried out the initial analyses, and reviewed and revised the manuscript; Dr Foix-L'Hélias conceptualized and designed the study, drafted the initial manuscript, and reviewed and revised the manuscript; Drs Arnaud, Marret, Vieux, Aujard, Thiriez, Larroque, Cambonie, Burguet, Boileau, Rozé, Kaminski, and Truffert critically reviewed the manuscript; Dr Ancel critically reviewed and revised the manuscript; and all authors approved the final manuscript as submitted.
FINANCIAL DISCLOSURE: The authors have indicated they have no financial relationships relevant to this article to disclose.
FUNDING: Funding for this study was obtained from INSERM (French National Institutes of Health and Medical Research), Directorate General for Health of the Ministry for Social Affairs, and "Hospital Program for Clinical Research 2001" (AOMO1117) of the French Department of Health. None of the funding bodies was involved in the design or running of the study; data collection, analysis, or interpretation; or the preparation, review, or approval of the manuscript.
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. Changes in pathogens causing early-onset sepsis in very-low-birth-weight infants. N Engl J Med. 2002;347(4):240–247pmid:12140299
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. Tertiary mechanisms of brain damage: a new hope for treatment of cerebral palsy? Lancet Neurol. 2012;11(6):556–566pmid:22608669
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. White matter injury after repeated endotoxin exposure in the preterm ovine fetus. Pediatr Res. 2002;52(6):941–949pmid:12438674
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. Prolonged reductions in placental blood flow and cerebral oxygen delivery in preterm fetal sheep exposed to endotoxin: possible factors in white matter injury after acute infection. J Soc Gynecol Investig. 2003;10(5):283–290pmid:12853089
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Copyright © 2013 by the American Academy of Pediatrics
You are going to email the following Neonatal Infection and 5-year Neurodevelopmental Outcome of Very Preterm Infants
Ayoub Mitha, Laurence Foix-L'Hélias, Catherine Arnaud, Stéphane Marret, Rachel Vieux, Yannick Aujard, Gérard Thiriez, Béatrice Larroque, Gilles Cambonie, Antoine Burguet, Pascal Boileau, Jean Christophe Rozé, Monique Kaminski, Patrick Truffert, Pierre-Yves Ancel
Pediatrics Aug 2013, 132 (2) e372-e380; DOI: 10.1542/peds.2012-3979
Fetus/Newborn Infant
Developmental/Behavioral Pediatrics


Here's a fantastic 1970 USAF educational documentary covering the mobilization, trainup, and deployment of USAF Air National Guard F-100 units. Narrated by the late Bob Crane of the television show Hogan's Heroes, the film chronicles the mobilization of four F-100 equipped ANG squadrons in response to the Pueblo Crisis during 1968. One particular two-ship mission is covered from pre-flight briefing to post-flight celebration.
The Super Sabre, better known as "The Hun" was the USAF's first supersonic fighter and formed the backbone of the USAF and many NATO and allied Air Forces prior to the arrival of the F-4 Phantom. The last Huns were retired from the Taiwanese and Danish air forces in the early 1980s, following USAF ANG retirement in 1979.
136th TFS Rocky's Raiders of the New York ANG (tail SG).
These four squadrons collectively logged more than 30,000 sorties during their deployments to Southeast Asia during 1968 and 1969, with some aircraft pulling up to five CAS sorties per day.
While the film may predate many of the SSD readership, many of our fathers and uncles likely owe their lives to "Weekend Warrior" CAS.
This entry was posted on Sunday, June 4th, 2017 at 00:01	and is filed under Air Force, Aviation, Cold War, History, Saturday Night Movie. You can follow any responses to this entry through the RSS 2.0 feed. Both comments and pings are currently closed.
That is cool seeing the KC-135 Stratotanker getting some love.
I've said it for over 20 years. Any Reserve / Guard aviation unit has NEVER been a "1 weekend a month, 2 weeks in the summer" job. The job is too demanding and complicated. Most "weekend warriors" I know, spend at least 1 week per month minimum, at the units flying days, nights and completing all types of other training.
"Weekend warriors" may be true for many of support folks but it has never been true for aircrews (pilots, flight engineers, crew chiefs etc).


text:
NewsInsider
The site of Campbell County's first school for black students is now a museum, thanks to NKU
Two-story building opened in 1873, closed in 1955
Posted: 10:00 AM, Dec 08, 2017
By: Vickie Ashwill | WCPO contributor
Vickie Ashwill | WCPO contributor

This is the new cornerstone that will be installed when the building is restored. The museum's official name is the Newport History Museum @ The Southgate Street School.

NEWPORT, Ky. -- In 1873, eight years after the Civil War, Newport opened the first school for black students in Campbell County.
Today, 144 years later, masters students in the Public History program at Northern Kentucky University have helped redefine the space on the first floor with displays that are the result of their research.
The end result: The Newport History Museum @ The Southgate Street School, a two-story brick building that educated the city's black children until 1955.
"It's a great project," said Brian Hackett, director of the Public History program at NKU. "How often as a graduate student do you get to set up the first exhibition for a museum?"
It's the city's first and only museum designed to mark the history of the school as well as the city's diverse background, said Newport historic preservation officer Scott Clark. Where else can one find a history of gambling, prostitution and a home to the Rat Pack, as well as a history of one of the largest steel factory developments and breweries in the United States?
The outside of the building will be renovated by the developers of the Fourth Street School site as part of their contribution back to the community. Renovations will include restoring the original tin trim along the top of the building.
Ten students worked on the project, Hackett said, researching everything from the school to gangsters, and spent time looking for artifacts from Newport that represent different periods in the city's history. Visitors will find an original school desk rescued from the building's basement as well as a state-issued arithmetic textbook where the bookplate indicates the book is for "colored" students.
Visitors to the museum can watch a hologram, also created by NKU students, of a former student talking about her sixth-grade experience there before the school closed.
The museum is a pet project of Clark, who worked with the Masonic Lodge, which owns the building and whose members wanted to preserve it. The Masons still use the upstairs space.
Funds to develop the museum came from a Mayerson Foundation grant to NKU's Scripps Howard Center for Civic Engagement and the East Row Historic District. The museum is under the Newport Foundation as a 501c-3, Clark said. Their only costs are maintaining the building.
A book used in the Southgate Street School. A close look at the bookplate shows that the state marked it for use in a black school only.
For Clark, the building is the heart of the project. It tells its own story -- closed-in windows on the interior structure where a second building was connected, worn treads on wooden stairs where students made their mark.
Developers of the nearby Fourth Street School, which will be made into apartments, are tasked with restoring the outside of the Southgate Street School since they are tearing down another historic structure, said Clark. That includes replacing bricks, tuck-point and painting as well as replacing the original tin cornice across the top of the building.
The original school was a one-room wood structure followed by a two-story brick building, said Clark. They can tell by the construction methods that a two-story addition was built in the back, giving the school four classrooms and a large basement space. At some point, a boys bathroom and girls bathroom was installed in the basement. In fact, a 1930s toilet remains. A stall door from the basement restroom is on display in the museum space.
Eventually the basement space with its 12-foot ceilings and concrete floor will become home to the museum's gambling artifacts as they collect them.
Scott Clark, Newport historic preservation officer, is the museum's director as well.
Mark Neikirk, executive director for civic engagement and nonprofit capacity at the Scripps Howard Center for Civic Engagement, said project-based learning is part of the culture at NKU. Students have done various projects on Newport's west side.
Multiple classes are involved with the museum. Students in a business informatics class will work on a funding model for the museum, and a public relations group is working on an advertising plan.
Students will continue to be engaged with the museum, said Clark. Their expertise and experience is invaluable to its growth.
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text:
Catching Forever
By Laurel Dee Gugler
In Stock Ships in 24hrs or or less
EPUB In Stock Ships immediately
Series: Lorimer Streetlights
Rating: 0 vote(s).
It's awkward enough for any kid going to a new school, but Rose, whose family belongs to a Mennonite community, feels even more out of place. Then, one day, she picks up a baseball.
Inspired by her own childhood memories, Laurel Dee Gugler paints a touching portrait of a young girl throwing herself into a new game and fresh possibilities.
Commended - Best Books for Kids and Teens Selection 2010 -
"Catching Forever is an easy read that grabs the reader's interest and allows the reader to appreciate the uniqueness of others. It is a book that many young readers would be able to relate to and would be a great resource when teaching young people about the importance of acceptance."
- CM: Canadian Review of Materials
Toronto-based author and storyteller LAUREL DEE GUGLER is perhaps best known for her popular picture books, including There's a Billy Goat in the Garden and Monkey Tales. She has also worked as a teacher, Education Coordinator of Hamilton Children's Museum, and the founder and coordinator of a multicultural storytelling group.
Publication Details:
Binding: Paperback, 104 pages
Publication Date: 30th May 2007
Format: 7.75in x 5in
Binding: Electronic book text
Publication Date: 1st August 2014
BIC Code: 1KBC, YFB, YFR, YX, YXL
BISAC Code: JUV014000, JUV030030, JUV032010, JUV039020, JUV039050
Imprint: Lorimer
Interest age: From 6 To 10


Today, we feature Emily Hall. This recent grad exemplifies a strong driven woman who chose a path of education to succeed in her career path of music. We wanted to share her experiences from her past couple of years; working at a label, sustaining a bi-coastal lifestyle, attending a wide variety of EDM events, and all while pursuing an undergraduate degree. We thought a lot of people could relate to her story of work, school, passion for electronic dance music, and dedication to this remarkable industry.
Congratulations Emily on your accomplishments!
We are extremely proud of you and wish you the best of luck with all of your future endeavors.
WOE: Where are you graduating from and with what degree?
EH: I am graduating from Florida Southern College, with a bachelor's degree in communications plus a minor in integrated marketing.
WOE: Where were you working or interning during school?
EH: During my four years of college, I experienced a few different opportunities working in the scene. My very first working experience was volunteering for ground control at EDC New York 2014, I attended EDC New York 2013 for my first music festival and knew I wanted to do more than just attend raves. A month later, I went to EDC Las Vegas where I met my now good friend Robby. He was building a team of writers for EDM.com at the time and encouraged me to apply.
By the end of summer 2014, I was blogging for EDM.com, this was when I started interviewing artists and going to events for press. I ended up writing for EDM.com for over two years, as well as freelanced for a few other online publications. At the beginning of 2016, I started handling the blog for Buygore Records, which led into a summer internship. For junior and senior year, I was also working part-time at LA Fitness in Connecticut, Florida, and California.
WOE: How did you acquire that internship and how long have you been doing it?
EH: One year at Miami Music Week, I met Christina Boemio at a Dim Mak event and at the time she was the publicist for Buygore. Later that year, we ran into each other at EDC Las Vegas and ended up spending the entire weekend together. From there we kept in contact through the LA-based collective Nap Girls that she co-founded. When 2016 rolled around, she reached out to me because Buygore needed someone to handle the blog.
During that same semester, I was enrolled in a pre-internship course and knew I wanted to intern somewhere in Los Angeles. Christina told me Buygore had an internship available over the summer and when I discussed it with the label manager Steven Pahel, he said also needed help with his artist management company SLVYVLL. So even though it was two companies they were still both out of the same office in Hollywood. I interned the entire summer and when it was over, they offered me the social media manager position, which I've been able to do remotely from Florida while finishing up my senior year.
WOE: What will you take with you from this internship?
EH: Working with the Buygore team showed me how important it is to have a good team. I loved working with everyone at the office and always looked forward to going in for work. Last summer was a lot of firsts for me, including living in Los Angeles, so it was a big learning experience all around.
WOE: How have you been able manage a job based out of LA and going to school in Florida?
EH: Being able to work remotely has definitely been super key to managing a job based out of Los Angeles and still going to school full-time. Especially now that I run the Buygore socials, it's a life savor being able to handle a lot of it from my phone so I'm able to multi-task no matter where I am or what I'm doing. Being so far away from Los Angeles also pushed me to work hard and be involved in any way that I could while living on the east coast.
WOE: What drove you to work so hard for so long?
EH: Through out high school, I really had no idea what my passion was. I was pretty involved in sports teams but still always felt out of place and never fully committed to it. I discovered the electronic music scene at the end of my second semester senior year in high school when my friend dragged me to a Life In Color event in Connecticut. Fast forward to my first semester as a college freshman, I knew I wanted to go to EDC Orlando but still didn't know too many people on campus.
I ended up going with this girl Julia, who became one of my best friends throughout college since we bonded over music, and then a random cluster of people from different friend groups who all just wanted to go and have fun. We had so much fun together even though we all barely knew each other, and it was that festival that really made me realize that I wanted to be more involved in the scene. I loved how music had the ability to bring people together and create a feeling of connectedness that I hadn't felt before, so when work opportunities started arising I never said no and just kept going with it because the scene was something I believed in.
WOE: For someone wanting to follow in your footsteps, would you suggest going to school for the same degree?
EH: When I enrolled in college, I still wasn't sure what career field I wanted to pursue, but I was drawn to event planning at the time. I knew I could apply a communications degree to a multiple fields so I wasn't putting myself into a situation with limited options. It wasn't until my sophomore year that I realized I wanted to try and pursue a career in music business, and I was luckily able to apply it. While I don't plan on pursuing advertising or public relations directly, it is nice being familiar with that aspect of the entertainment business. I'd definitely suggest trying to find a program within the music business realm, but at the end of the day nothing beats real life experience.
WOE: Any additional tips for someone who wants to pursue an internship within the EDM industry?
EH: Get involved any way you can. Whether it's volunteering or promoting, it's always good to have some experience to give you a leg up. Getting different experience also helps with figuring out with aspect of the industry you want to work in. Most importantly, make yourself present in the scene and be apart of it because you never know who you're going to meet.
WOE: Are you involved in any other EDM related organizations?
EH: I've been apart of Nap Girls for around two years now, and it's definitely been an awesome resource to have as well as very eye opening. It's really cool to constantly see what other women in the industry are doing and helping each other succeed in our careers.
WOE: What have you learned from being a Nap Girl?
EH: If you haven't heard of Nap Girls, it's a collaborative organization whose mission is to connect and empower women and GNC individuals by nurturing creative and professional growth. Being a Nap Girl has taught me how important it to empower others versus competing against others. It has also shown me how sexism is still very real within the industry, but also how to combat sexism and overcome these challenges. I am so inspired by other Nap Girls and the network of friendships this group has created has been really nice to have during my transition to LA.
WOE: In addition to your bi-coastal priorities, how do you maintain your exciting EDM lifestyle?
EH: My parents have been huge supporters since I discovered my passion for music. They've both been pretty involved in the whole process of pursuing music and I couldn't have done any of it without them. I was also really lucky to be located in both Florida and right outside of New York, as they're both big areas for the music scene. Traveling to different festivals is one of my favorite things to do, and I've been super fortunate to be able to travel and experience new places. Some festivals have been a tradition for more than a few years now, especially the EDC Las Vegas B2B Electric Forest trip. Now that I'm graduated, I'm definitely trying to experience new festivals and travel to places I haven't been before.
WOE: What are your plans for the future?
EH: With my college years finally behind me, I'm really excited to see where the future takes me. Even though I live near New York City, I fell in love with Los Angeles last summer and I can't wait to go back. I plan to continue working with the Buygore Records and SLVYVLL Management team, as I want to start focusing more on the artist management side of things. Definitely looking forward to what the rest of 2017 has in store.


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[Watch] Ajinkya Rahane has his name engraved on MCG Honours Board for the second time
Ajinkya Rahane features on the MCG Honours Board for the second time. Pic: BCCI/ Twitter
Following his captain's knock of 112 in the Boxing Day Test against Australia, Ajinkya Rahane got his name engraved on the MCG Honours Board for the second time.
Rahane's century at the Melbourne Cricket Ground gave India a decisive first-innings lead, which eventually allowed the visitors to level the Border-Gavaskar Trophy 1-1.
BCCI's official Twitter account shared the proud moment of Ajinkya Rahane's name being put up on the honours board. Watch video below:
After leading from the front with a fantastic ton in the Boxing Day Test against Australia, @ajinkyarahane88 has his name engraved on the MCG Honours Board for the second time. 👏👏#TeamIndia #AUSvIND pic.twitter.com/z7vDe5dG4U
— BCCI (@BCCI) December 30, 2020
The MCG honours board features names of cricketers who have either scored a century or picked up a five-wicket haul at the famous venue.
Before Ajinkya Rahane, New Zealand's Tom Blundell was the last batsman to have his name engraved on the MCG Honours Board following his 121 in December 2019.
Ajinkya Rahane had featured on the MCG Honours Board for the first time following his 147 during the 2014 Boxing Day Test. Other famous Indian batsmen part of the hallowed list are Vinoo Mankad, Sunil Gavaskar, Gundappa Viswanath, Sachin Tendulkar, Virender Sehwag, Virat Kohli and Cheteshwar Pujara.
Prominent Indian bowlers too have their names engraved on the MCG Honours Board. Erapalli Prasanna, Bhagwat Chandrasekhar, Kapil Dev, Anil Kumble and Jasprit Bumrah have all claimed five-wicket hauls at the MCG.
Ajinkya Rahane's love affair with Melbourne
India's stand-in skipper Ajinkya Rahane has a sensational record at the MCG. In three Tests at the venue, the 32-year-old has scored 369 runs at an average of 73.80, with two hundreds.
Rahane hit 147 and 48 during his first Test in Melbourne in 2014. During India's memorable win in 2018, he contributed only 34 and 1.
However, under pressure following the Adelaide disaster in the first Test of this series, Rahane led from the front with scores of 112 and 27 not out as India ended 2020 with a win.
Special team, special win 🇮🇳 pic.twitter.com/0SpJ6psra6
— Ajinkya Rahane (@ajinkyarahane88) December 29, 2020
During the course of his hundred in Melbourne, Ajinkya Rahane overtook Virat Kohli as India's second-highest run-getter at the venue.
Kohli has scored 316 runs in three Tests at the MCG at an average of 52.66. This includes one hundred and two fifties.
Sachin Tendulkar is the leading run-getter for India at the MCG, with 449 runs in five games at an average of 44.90. The record includes one hundred and three fifties.
With his second hundred at the MCG, Ajinkya Rahane also joined Vinoo Mankad as the only Indians to have scored two Test centuries at the venue.
India vs Australia 2020-21 Australia Cricket Team Indian Cricket Team Virat Kohli Ajinkya Rahane


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Sir David Attenborough Stabbed By 'Dangerous' Cactus While Filming New Series
Frankie Golding
Well, the good news is that we'll soon be getting a new Sir David Attenborough series – hooray!
But the bad news is that a cactus with 'needles like glass' had the audacity to stab our national treasure in the hand while filming it.
Now don't panic, the 95-year-old is absolutely fine and you're not about to find out that everyone's favourite environmentalist has been severely injured by a cactus, however being pricked by one of these things was apparently rather painful.
This incident occurred while the naturalist and broadcaster was investigating the cholla cactus in California during shooting for The Green Planet on BBC One.
However, despite wearing the combined protection of a Kevlar under-glove and a welding glove, the measures failed to prevent him from being hurt by 'spicules of glass' while reaching inside the plant.
Sir David said: "The cholla really is a physical danger.
"It has these very dense spines in rosettes, so they point in all directions.
"And if you just brush against it, the spines are like spicules of glass, I mean they are that sharp and they go into you and you really have trouble getting them out.
"So that is a really dangerous plant. The cholla is an active aggressor. I mean, you feel you better stand back and you better watch out."
Sounds to me like the BBC should have forked out for an extra glove for our hero.
Credit: Alamy
Executive producer Michael Gunton added: "One of the joys of going on location is thinking up horrible things to get [David] to do.
"So what we did, because it was so dangerous, was we got a Kevlar under-glove, and then on top of that, a welding glove.
"So you can imagine that's about as good protection as you could possibly get.
"So, David bravely put his hand inside this cholla cactus, as requested. And halfway through it, these spikes still managed to get through those two bits of protection.
"And it's quite painful, isn't it?"
The Green Planet will see Sir David travel across the globe, from the US to Costa Rica and across Europe to different terrains including deserts, water worlds, tropical forests and the frozen north.
According to the BBC, the new series aims to show 'how science and technologies have advanced, and how our understanding of the ways in which plants behave and interact has evolved'.
It uses ground-breaking filming techniques to show viewers the intricate lives of plants and the ecosystems that flourish around them – and the ways in which they are just as aggressive as animals.
In November, the series had its global premiere in Glasgow in conjunction with the COP26 summit on tackling climate change.
The Green Planet begins on BBC One on 9 January.
Featured Image Credit: Alamy
Topics: David Attenborough, BBC, Environment, News
Sir David Attenborough Is Dropping A Docuseries About Dinosaurs
Sir David Attenborough Has Been Named 'Champion Of The Earth'
David Attenborough brings viewers to tears as he makes 'urgent final plea'
Former US President Barack Obama beats out David Attenborough for nature documentary Emmy


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I have such query and if nesting rise to more then three I must end query.

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Home » Medications » Genetic tests to select embryos with a high IQ will become the norm
Genetic tests to select embryos with a high IQ will become the norm
According to the publication New Scientist, the firm of Genomic Prediction has begun negotiations with several companies in the United States involved in IVF. We are talking about the production of genetic tests that will allow the conception of a child using this procedure in advance to identify and discard embryos with a low IQ. Although these tests are considered to be ethically controversial, the circumstances are such that they most likely already quite soon will become the norm.
How realistic is it to carry out genetic tests on embryos to detect the risk of some diseases and the level of intelligence? Humanists consider that this is breeding anti-human. In medicine, these genetic tests are not used. But, apparently, only so far. Scientists themselves admit that the practice of such testing will become the norm over time. As stated by geneticist at the University of Queensland Peter Vischer, the use of tests to select embryos that have the preconditions of high intelligence, "disgusting, but technologically possible."
In Genomic Prediction, the company engaged in the development of genetic tests, abandoned the idea to identify embryos with a potentially high level of IQ that were destroyed "less intelligent". They stopped for tests to determine the predisposition to serious diseases. But the company believes that other firms will still do the practice testirovanija embryos for intelligence is the norm in the very near future.
"I think the people themselves will demand it. If we don't do that, make another company," said co-founder of the company Steven Xu.
The tests that have learned to hold in his company, help to identify the potential risk of heart disease, breast cancer, diabetes first and second type, of irritable bowel syndrome and other disorders, including anomalies of mental development. Appreciating these achievements, many scientists are convinced: to identify embryos with the highest IQ after that all will go inevitably.
Magicforum previously wrote about creating a test for the selection of embryos in IVF with high intelligence.
Found a substance that makes the body fight cancer
Same-sex parents carried the child together
In rodiola pink discovered a substance that improves memory
Computers will return it paralyzed people
For the first time in history an electric skateboard hit-and-run death
« Defective protein factories in disease: A double-edged sword of cell division
City of Kawartha Lakes issues boil water advisory for Janetville »


TimeWorked was first developed for a firm of Insurance Loss Adjusters. As well as the general consultancy practice management modules there are the specific modules designed for Insurance Loss Adjuster use. In particular the system caters for iterative draft and final draft invoicing. The system allows invoices to be split between multiple clients - for example between the Insurer, Reinsurer, and Broker. The invoices include automatically generated summary and detailed breakdowns of time, expenses, and disbursements.
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If you are an Insurance Loss Adjuster and would like a comprehensive solution to meet your company's practice management needs, please email suppor@timeworked.com to be provided with a free trial of the software.


The frameless shower doors noted to be catching up with the new modern house trends, studies indicate the number of people who prefer to order for the frameless doors when remodeling their houses is high. Studies indicate the number of people who are installing the frameless doors have increased due to the popularity that been created from installation of these shower doors. The frameless glass shower doors been preferred by many homeowners who noted their bathrooms are small, studies indicate many of the people who have installed bathtubs in small bathrooms are now shifting to the frameless glass doors to ensure the bathroom opens up and they have enough room. A great advantage realized with the addition of space from getting rid of the bathtub is there is more light that is allowed to the room and the owner no longer has to deal with liners that needs to be replaced every couple of months.
Many homes are noted to enhance the authenticity of the bathroom and one of the definite ways to ensure this is installing the modern frameless glass door that ensures the bathroom gets the desired look. The objective of every homeowner is toe ensure the bathroom looks and feel cleaner, one of the best ways to ensure this is achieved is by installing the frameless glass doors. Therefore, in order to ensure the modern look of the door is enhanced, the owner can decide to pick on a unique design to ensure the desired look is achieved. Frames identified to be affected by corrosion especially if they exposed to so much water, but with the frameless glass shower doors the individual are noted to be able to avert issues regarding corrosion of the frames. For the safety of the homeowner the showers are watertight sealed thus the homeowner does not have to worry of any water leaks.
Studies indicate home upgrades are expensive, this has resulted to many people only upgrading the homes if they have to, but with the installation of the frameless glass doors is identified to be cheaper and over time has encouraged many people to install. When considering to sell the house, many people are noted to ensure they upgrade the house in order to attract a better market price, one of the most definite ways is to have a bathroom upgrade that is noted to be an inexpensive way to do so in order to get the desired price in the market. Finally, it is noted many people are able to customize the glass doors of the showers, this allows the people to be in a position to get their desired door designs that best showcases their bathrooms in a very affordable price.


Apple may provide or recommend responses as a possible solution based on the information provided; every potential issue may involve several factors not detailed in the conversations captured in an electronic forum and Apple can therefore provide no guarantee as to the efficacy of any proposed solutions on the community forums. To learn about Service and support, discussions, tutorials, and. If you haven't , find your iPad in the list and use the manual appropriate for that model. Your iMac appears as a disk drive on the other computer and you can transfer files. If you have an iPad Air or more recent iPad, you can do slide-over multitasking, which lets you run an app in a column to the side of your iPad.
Remove the memory modules from your iMac. As you get to know your iMac, explore the system preferences. Use the information that follows to connect to the Internet. Drop-and-drag also came to the iPad, which makes sharing files and objects across apps even easier. For information about using the AirPort Extreme Base Station, check Mac Help or visit the AirPort Support website at www. Because of the optical disc drive in your computer, your computer is a Class 1 laser product.
To install applications: Back up your important files. The safety information part is so badly written as to be misleading and is likely to increase mishaps leading to injury. But that doesn't mean that Apple doesn't make manuals for the nano. But perhaps the best feature of the update is the , which lets you use the on-screen keyboard like a laptop's touchpad. But I think that even a new user will find this Guide helpful, easy to read, easy to follow. Range may vary with site conditions.
This allows new photo filters downloaded from the app store to work inside the Photos app and new widgets to be available on the notifications screen. You can also stream content from other iTunes libraries on your network. When your iMac is in sleep, its screen is dark and a small white light below the lower-right corner of the display pulses. Besides that, it sports a clip on the back, a touchscreen, and removes the clickwheel and video camera that the 5th generation model offered. Where can I find my model number? When the icon for the disc appears on the desktop, the disc is ready to use. Do not attempt to open your iMac. Your iMac is set to automatically check once a week but you can set it to check daily or monthly.
The model number can be found on the original box the item was purchased in, on the product manual, and on the product in the locations described below. Once you know if that's the model you've got or not:. It just doesn't print them anymore. Chapter 3 Using Your iMac. When your product reaches its end of life, contact Apple or your local authorities to learn about recycling options. Important Care and Cleaning Information. When your iMac is on, this light is off.
Once you know that you've got this model: The 2nd Generation iPod nano looks reasonably similar to the original model, with one big difference: color. Chapter 3 Using Your iMac. When you plug a pair of headphones or another device into the mini-phono jack, sound comes through the device instead of the iMac speakers. For your safety, have this equipment serviced only by an Apple-authorized service provider. However, you can stream from only one iTunes library at a time. These manuals are geared more towards the operating system than the actual device. Press this button with a small object.
To hide the open windows and see the desktop, press F11. More Information About Ergonomics Go to www. You can also play music through your home stereo with iTunes and an AirPort Express Base Station. Apple disclaims any and all liability for the acts, omissions and conduct of any third parties in connection with or related to your use of the site. If you connect more than two devices, the rest of the devices in the daisy chain should be powered by separate power adapters. Your iMac is set to check automatically once a week but you can set it to check daily or monthly.
Memory modules must be installed in pairs and meet the following specifications: Â. Read this section to learn how. All postings and use of the content on this site are subject to the. Helpful tip: For convenience, if you have a digital camera or smart phone, you may want to take a digital photo of the model number. FireWire lets you easily connect and disconnect external high-speed devices—such as digital video cameras, printers, scanners, and hard disks.


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Imagine what you want to accomplish, then really making it happen. Imagine designing and publishing a video game before earning your diploma, starting a business while studying business, and doing all this in a setting that begs you to get out and do something. Imagine, then Do. Opportunity awaits and all things are possible at a place we call Imagine U. The University of Utah.
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Journalism & Media (1)
Originally named the University of Deseret, the University of Utah is the oldest state university west of the Missouri River. Founded in Salt Lake City on 28 February 1850, the school's first term - for men only - in November of 1850. The second term was opened to both women and men. At the end of the third term in 1852, classes were discontinued because of lack of funds.
We invest in students to prepare them, and the community, for a bright and healthy future.
We consider ourselves the perfect size: big enough to have resources, small enough that we're open to outside ideas. Collaboration is in the DNA of the researchers that call Utah home, and we know that combining ingenuity with dedication can create a sum that is far grander than its parts.
Our team helps develop greater self-understanding, expand awareness of career opportunities, and foster effective job search practices which can be applied throughout a lifetime. Each year, University of Utah graduates accept professional employment offers around the world. Discover the variety of career outcomes achieved by University of Utah students.
Academic Ranking of World Universities by Shanghai Jiao Tong University
ARWU World University rankings is the first world university ranking. It ranks the world's top 1000 colleges and universities based on objective indicator.
They look at the number of award-winning (Fields Medals and Nobel Prize) scientists who are located there, how much of their research is cited and referenced around the world, and how much they've contributed to different academic fields. After calculating and comparing these criteria, ARWU ranks the universities accordingly.
World University Rankings by Times Higher Education
World University Rankings is a vital resource that provides the definitive list of the world's best universities.
They look at how often they're producing new ideas, what their reputation is around the world, and how much they're contributing to science and academic fields. After calculating and comparing these criteria, THE ranks the universities accordingly.
QS World University Rankings by TopUniversities
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QS World University Rankings is one of the top international rankings measuring the popularity and performance of universities all over the world.
They measure university reputation based on the impressions of higher education experts, companies who hire graduates, and teaching quality. QS also considers the ratio of international teachers and students present at universities, as well as the times research papers were mentioned by researchers. After calculating and comparing these criteria, QS ranks the universities accordingly.
Best Global Universities Rankings by U.S. News & World Report
Best Global Universities Rankings by U.S. News & World Report presents all the top universities from the U.S. and 60 other countries around the world.
They measure the rate of students going to their second year of studies, as well as the rate of students who graduate. It also asks university representatives on the performance of universities, and evaluates university resources, teacher salaries, graduation rates, student academic achievements and satisfaction. After calculating and comparing these criteria, U.S. News ranks the top international universities accordingly.
The International Student & Scholar Services office serves as the primary campus contact for international students, scholars, and alumni. Our office fosters and supports a global campus community as part of the University of Utah's vision of a welcoming and internationally connected campus.
The Accommodations Policy Committee, chaired by Kate Coles, Professor of English, developed this policy after more than 20 meetings with students, faculty and community members. In addition to Professor Coles, there were three student, two faculty, one staff, and one community member on the Committee.
The libraries present at University of Utah are:
Spencer S. Eccles Health Sciences Library
James E. Faust Law Library
McKay Music Library
UMail is the official form of email communication at the University of Utah.
Box is an online cloud storage and collaboration tool.
Canvas is the University's Online Learning Management System where portions of classes or entire courses can be published or managed.
Campus Information Services (CIS) contains a variety of self-service apps.
KRONOS is the U's automated payroll system.
University of Utah Health is the Mountain West's only academic health care system, combining excellence in patient care, the latest in medical research, and teaching to provide leading-edge medicine in a caring and personal setting. The system provides care for Utahns and residents of five surrounding states in a referral area encompassing more than 10 percent of the continental United States.
Located just west of the George S. Eccles 2002 Legacy Bridge and adjacent to the Fort Douglas TRAX stop, the George S. Eccles Student Life Center connects student life with academic life and creates a more engaged campus community. This is your place for recreation, relaxation, and socializing!
Amenities include a 50-meter pool, indoor and outdoor leisure pools, large indoor hot tub/spa, 320-yard indoor running track, bouldering & 4-story climbing wall, 15,000 square foot fitness center, outdoor mezzanine, outdoor fire pit, 5 sport courts, racquetball courts, 4 group fitness studios, and a combative room.
As an integral part of the University and the community, the Athletics Department complements and supports the overall mission of the University. The Athletics Department seeks to provide the means for all student-athletes to reach their full potential academically and athletically, while also becoming positive contributors to society.
The Athletics Department supports the University's objective of creating an inclusive community that is enriched by the life experiences and backgrounds of a diverse and excellent staff and students. The Athletics Department strives for winning teams that adhere to NCAA and Pac-12 rules and display loyalty, honesty, fiscal soundness and good sportsmanship.
The University of Utah has clubs relating to athletics and recreation, arts and entertainment, academic and professional development, and social/multicultural. ASUU coordinates and supports over 600+ student groups on campus for you to join. We provide funding, advice and more ways for you to find and connect with students that share your interests. To make it easier to search, join or create a club, ASUU has a student group website called OrgSync.
The Hinckley Institute of Politics at the University of Utah runs one of the nation's oldest internship programs. Each year, the Hinckley Institute places nearly 400 students locally, nationally, and globally in a wide range of government, nonprofit, think tank, and business organizations. For five decades, the Institute has championed the learning outcomes of engaging multidisciplinary students in civic processes and practical politics.
University of Utah Review
Anonymous rated 4 out of 5 stars
I loved my study experience at this university. The professors were great and take the time to know you personally. Like every other college, some classes can just be a little too long.
Throw up your U
I loved my experience at the University of Utah. I'd attended two other universities and didn't love my experience at either one, but found my home at the U. In the business school, we had professors who were a combination of academics and professionals, giving us a more rounded view on business as a whole.
∞ Snow College ∞ Ephraim, UT, USA.
Snow College is an amazing college. They are involved in the global and local community. The only reservation I have is that it is in the middle of no where Utah. It does mean that the only thing you have to focus on is your studies. It is an amazing college that cares about every student.
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Nocilla is a Spanish brand of hazelnut and chocolate spread similar to Nutella. It is sold in Spain and Portugal, was first launched in the late 1960s, and after its acquisition from Unilever in 2002 has been manufactured by Nutrexpa.

Slogan
Leche, cacao, avellanas y azúcar... ¡¡No-ci-lla!!: "Milk, cocoa, hazelnuts and sugar... No-ci-lla!!"

History
At the end of the 1960s, the Starlux group was inspired by a product of the Italian Ferrero group, the Nutella spreadable cream, to develop its own product for the Spanish market. Nocilla dough has a third less hazelnut paste than Nutella. Nocilla's first slogan was ¡Qué snack! To make itself known among young people, Nocilla sponsored sports camps, children's events and bet heavily on advertising. In this way, Nocilla positioned itself as the main brand in its sector.

In 1997, Starlux shareholders sold the firm to the Knorr group, which later passed into the hands of the Anglo-Dutch multinational Unilever. Five years later, the owners sold the brand to Grupo Nutrexpa, known for being the manufacturer of Cola Cao. Under their management, Nocilla launched new flavors and other products, such as buns. After the division of Nutrexpa into two companies in 2014 and the distribution of the products of the old Nutrexpa between the two new companies that began operating in 2015, Nocilla was under the ownership of Idilia Foods, which is the one who manufactures it today.

See also
 List of spreads

References

External links
Official website
Brand information at Nutrexpa site.

Spreads (food)
Spanish brands
Spanish cuisine
Products introduced in 1967
Brand name condiments
Brand name chocolate

redpajama_set_name: RedPajamaWikipedia


text:
Q: Help with an exponential function with an indicator and using the EM Algorithm Two bulbs, Brand A and Brand B, in which their lifetimes are distributed exponentially with expectations $\lambda$ and $\mu$ respectively.  They pair $X_i$ and $Y_i$.
In the ith experiment, instead of letting both two bulbs
burn until they die out, they stop when one of the bulbs burn out, and record
the burning time $Z_i$ and indicator $W_i$ of which one burns out.  This is repeated $n$ times.
$Z_i = min(X_i,Y_i)$, and $W_i = \begin{cases}
\;\;1,\quad if \;Z_i=X_i,\\
\;\;0,\quad if \;Z_i= Y_i.
\end{cases}$
When applying the EM algorithm, I am trying to show that $$\lambda^{(k+1)}=\frac{\sum_i^n w_iz_i+\sum_i^n(1-w_i)(z_i+\lambda^{(k)})}{n}$$ $$\mu^{(k+1)}=\frac{\sum_i^n (1-w_i)z_i+\sum_i^nw_i(z_i+\mu^{(k)})}{n}$$
Here's where I am with my attempt:
I know that $Z_i$ is independent and the joint likelihood function is: $L_n(W,Z,\mu,\lambda)=\lambda^{\sum w_i}\mu^{n-\sum w_i} e^{-(\lambda+\mu)\sum z_i}$
and the log-likehood is:
$l_n=\sum w_i ln(\lambda)+(n-\sum w_i)ln(\mu) - (\lambda+\mu)\sum z_i$
I am stuck on between the E and M step.  Any advice would be appreciated!
Thank you!