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Showing items 1 - 20 of 460
12National Union of Metalworkers of South Africa 8Congress of South African Trade Unions (COSATU) 7Transport and General Workers' Union (South Africa) 5COSATU 5Food and Allied Workers' Union 2Congress of South African Trade Unions 2Jacobs, Lumkile 2Machiri, Mwazvita Chipo 2Mbaba, Mziyanda 2South African Commercial, Catering, and Allied Workers Union 2Zwane, Tinky 1Abraham, Benjamin Melakail 1Adeniyi, Omotayo Kayode 1Adeoyo, Olusegun Richard 1Adesina, Abiola Olanike 1Afolayan, Anthonia Folake 1Agbor Ambang, Oscar Mbi 1Allen, Jennifer Ann 1Amusengeri, Arnold 1Angus, Catherine Clare
38Workman family -- Photographs
260Adobe Acrobat PDF 200JPEG Image 1Excel Microsoft Office Open XML Format document
260text 167still image 90Master's theses 55Doctoral theses 38thesis 35pamphlet 33Image 27Masters 25Doctoral 25PhD 16MSc 14Thesis 12Academic theses 12book 5MA 2MSc (Pharmacy) 1Diploma theses 1M.Pharm 1MBA 1MCOM
241English 16eng 3Xhosa
452020 272021-10-29 252018 192017 132021-03 81990-06 82022-10-14 72015 72022-04-06 62012 62019 52014 52016 52021-11 42015-01 42017-02 42021-06 42022-02 42022-03-13 32014-02
Exploring targeted metagenomics and untargeted metabolomics for characterising aquaponics bacterial ecology and phytochemistry
Authors: Abraham, Benjamin Melakail
Type: Master's theses , text
Identifier: http://hdl.handle.net/10962/192453 , vital:45227
Description: Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 2021
Design of Immunobiosensors for Detection of Tumor-Associated Anti-P53 Autoantibodies: Method Development
Authors: Adeniyi, Omotayo Kayode
Type: thesis , text , Doctoral , PhD
Identifier: http://hdl.handle.net/10962/162988 , vital:41002 , 10.21504/10962/162988
Description: Introduction -- Experimental -- Label-Free Impedimetric Sensing of Anti-P53ab... -- Fluorescent detection of Anti-P53ab -- Peroxidase-like activity of Fe3O4@SiNP-APTES-Au@Pd... -- Colorimetric detection of Anti-P53ab , Thesis (PhD)--Rhodes University, Science Faculty, Department of Chemistry, 2020. , Detection and profiling of circulating tumor-associated autoantibodies (TAAbs) are useful for screening and early-stage diagnosis of asymptomatic lung cancer. Immunobiosensor technologies aimed to accomplish the highly sensitive, rapid and low-cost detection of TAAbs can improve the early-stage detection of lung cancer. Immunobiosensors for the detection of anti-P53-tumour associated autoantibodies have been developed in this work. The design of sensing interfaces with immobilized P53 protein (P53ag) as a sensing element layer on a solid interface was investigated. Several methods of detecting anti-P53-antibodies (anti-P53ab) were investigated. These methods are label-free detection using electrochemical impedance spectroscopy (EIS) and two label techniques. The label-free electrochemical techniques utilize gold electrode pre-modified with a conducting layer of electrochemically grafted phenylethylamine for covalent immobilization of P53ag. The limit of anti-P53ab detection with the label-free EIS was 103.0 pg.ml-1. The labeled technique developed utilizes fluorescent, and peroxidase-like nanomaterial labeled antibody as a detection probe. For the fluorescence detection, fluorescent silica nanoparticles were synthesized by overloading FITC into the silica matrix and conjugated to detection antibody (anti-IgG). The detection of the anti-P53ab was based on the dissolution of the silica nanoparticles to release the loaded dye as a signal amplification strategy. The fluorescence detection was carried out on a microplate, and magnetic bead modified P53-antigen platforms and limit of detection (LoD) were 42.0 fg.ml-1 and 3.3 fg.ml-1 for anti-P53ab; respectively. Fe3O4@SiNP-APTES-Au@Pd hybrid nanoparticles were synthesized, and their peroxidase-like activity and colorimetric detection were evaluated. The Fe3O4@SiNP-APTES-Au@Pd exhibited comparable activity to HRP. The Fe3O4@SiNP-APTES-Au@Pd was conjugated to protein-G-anti-IgG for the detection of anti-P53ab on a microplate and cellulose paper platforms. The LoD was 20.0 fg.ml-1 and 63.0 fg.ml-1 for the microplate and cellulose paper platform; respectively. The potential application of the designed immunobiosensor was evaluated in simulated serum samples. The developed sensors showed higher detection sensitivity, stability and had a lower detection limit for anti-P53ab when compared with the ELISA based detection. The results have provided alternative and effective quantification approaches to ELISA and a promising future for multiplexed detection of tumor-associated autoantibodies. The developed methodologies in this thesis could be applied for the detection of other autoantibodies in other cancer types and auto-immune diseases.
Bioprospecting for amylases, cellulases and xylanases from ericoid associated fungi, their production and characterisation for the bio-economy
Authors: Adeoyo, Olusegun Richard
Type: Doctoral theses , text
Description: South Africa is one of the most productive areas for ericaceous plants with about 850 identified species in the Cape Floral Region. The Albany Centre of Endemism where all fungi used in this study were isolated from, falls within this region. Ericaceous plants interact with some fungi via an association called the ericoid mycorrhizal (ERM) association. All fungi used in this study were isolated from roots of six ericaceous plants; Erica cerinthoides, Erica demissa, Erica chamissonis, Erica glumiflora, Erica caffra and Erica nemorosa. Fungal enzymes are known to play a significant role in the food, brewing, detergent, pharmaceutical and biofuel industries. The enzyme industry is among the major sectors of the world, and additional novel sources are being explored from time to time. This study focussed on amylases (amyloglucosidase, AMG), cellulases (endoglucanase) and xylanases (endo-1,4-P-xylanase) production from ERM fungal isolates. Out of the fifty-one (51), fungal isolates screened, ChemRU330 (Leohumicola sp.), EdRU083 and EdRU002 were among the fungi that had the highest activities of all the enzymes. They were tested for the ability to produce amylases and cellulases under different pH and nutritional conditions that included: carbon sources, nitrogen sources and metal ions, at an optimum temperature of 28°C in a modified Melin-Norkrans (MMN) liquid medium. Cellulase specific activity of 3.99, 2.18 and 4.31 (U/mg protein) for isolates EdRU083, EdRU002 and ChemRU330, respectively, was produced at an optimal pH of 5.0. For amylase, ChemRU330 had the highest specific activity of 1.11 U/mg protein while EdRU083 and EdRU02 had a specific activity of 0.80 and 0.92 U/mg protein, respectively, at the same pH with corresponding biomass yield of 113, 125 and 97 mg/50 ml, respectively. Increased enzyme activities and improved mycelial biomass production were obtained in the presence of supplements such as potassium, sodium, glucose, maltose, cellobiose, tryptone and peptone, while NaFe-EDTA and cobalt inhibited enzyme activity. ChemRU330 was selected to determine the consistency and amount of amylase, cellulase and xylanase formed after several in vitro subculturing events. AMG and endo-1,4-P-xylanase were found to have the most consistent production throughout the study period. The AMG was stable at 45oC (pH 5.0), retaining approximately 65% activity over a period of 24 h. The molecular mass of AMG and endo-1,4-P-xylanase were estimated to be 101 kDa and 72 kDa, respectively. The Km and kcat were 0.38 mg/ml and 70 s-1, respectively, using soluble starch (AMG). For endo-1,4-P-xylanase, the Km and Vmax were 0.93 mg/ml and 8.54 U/ml, respectively, using beechwood xylan (endo-1,4-P-xylanase) as substrate. Additionally, crude extracts of five root endophytes with unique morphological characteristics were screened for antibacterial properties and was followed by determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). L. incrustata (ChemRU330) and Chaetomium sp. extracts exhibited varying degrees of inhibition against two Gram-positive and Gram-negative bacteria. The crude extract of L. incrustata was the most effective which was found to inhibit Staphylococcus aureus (MIC: 1 mg/ml), Bacillus subtilis (MIC: 2 mg/ml) and Proteus vulgaris (MIC: 16 mg/ml). The L. incrustata displayed potential for antibacterial production and could be considered as an additional source of new antimicrobial agents in drug and food preservation. Also, the three isolates used for enzyme production were identified to genus and species levels, i.e., Leohumicola incrustata (ChemRU330), Leohumicola sp. (EdRU083) and Oidiodendron sp. (EdRU002) using both ITS and Cox1 DNA regions. The molecular analysis results indicated that these ERM mycorrhizal fungi were similar to those successfully described by some researchers in South Africa and Australia. Therefore, this study opens new opportunities for exploring ERM fungal biomolecules for the bio-economy. The promising physicochemical properties, starch and xylan hydrolysis end- products, and being non-pathogenic make AMG and endo-1,4-P-xylanase potential candidates for future applications as additives in the food industry for the production of glucose, glucose syrups, high-fructose corn syrups, and as well as the production of bioethanol. Finally, the findings of this study revealed that it is possible to produce hydrolytic enzymes from ERM fungi in vitro using chemically defined media. , Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2018
Design of immunosensor for the detection of C-reactive protein using oriented antibody immobilization
Authors: Adesina, Abiola Olanike
Identifier: http://hdl.handle.net/10962/163080 , vital:41010 , https://dx.doi.org/10.21504/10962/163080
Description: Thesis (PhD)--Rhodes University, Science Faculty, Department of Chemistry, 2020.
The design, synthesis and antiplasmodial activity of a series of halogenated fosmidomycin analogues and hybrid drugs
Authors: Afolayan, Anthonia Folake
Type: text , Thesis , Doctoral , PhD
Description: Malaria continues to be a devastating disease and a major cause of death in sub-Saharan Africa. With resistance against most of the available antimalarial drugs, there is a need for ongoing research and development of antimalarial agents. Fosmidomycin and its acetyl analogue FR900098 have been identified as potent inhibitors of Plasmodium falciparum, the causative agent of the most deadly form of malaria. Clinical trials of these agents have revealed poor absorption due to their high hydrophilicity. In the present studies the effect of halogenation of the acyl chain as well as the biological effect of extending the acyl sidechain was explored. This provided the basis on which fosmidomycin hybrids were designed to investigate the feasibility of hybrid extending into NADPH binding pocket. Synthesis of a series of halogenated FR900098 analogues was carried out in three stages. This included i) The introduction of the phosphonate group by reaction with 1,3dibromopropane in an Arbuzov reaction, ii) The introduction of a hydroxamate group by reaction of the propyl phosphonate by means of a nucleophilic substitution reaction with BocNHOBn and iii) The introduction of a halogenated acyl side chain on a protected fosmidomycin backbone. The synthesis of fosmidomycin-hybrids for which chloroquinefosmidomycin hybrids were used as the prototype, involved convergence of the two separately constructed moieties i.e. fosmidomycin and the quinoline moieties in a covalent linkage. The quinoline moiety was easily synthesized from the reaction of 4,7dichloroquinoline with 1,2-diamino ethane. The aminoquinoline so formed resulted in chloroquine-fosmidomycin hybrids 3.8 and 3.9 when reacted with halogenated FR900098 analogues. Antiplasmodial assays were conducted on the chloroquine-fosmidomycin hybrids and the halogenated fosmidomycin derivatives against the chloroquine resistant Gambian FCR-3 strain of P. falciparum. The most potent iodoacetyl fosmidomycin analogues 2.21 gave an IC50 value of 5.54 µM which is eight times more potent than the known antiplasmodial FR900098 which gave an IC50 value of 41.67 µM. All the halogenated FR900098 analogues showed better antiplasmodial activity than their non-halogenated derivatives. This indicated that the presence of halogens in the FR900098 analogues contributes to their biological Chapter 1 Literature review activity. The acetyl and propyl linked hybrids 3.8 and 3.9 showed potent antiplasmodial activity with IC50 values of 0.18 and 0.82 µM respectively. These were by far the most potent hybrids synthesized and provided leads for a new class of promising antimalarial agents. Preliminary E. coli DXR enzyme inhibition assays were carried out on the halogenated fosmidomycin analogues. The results showed good inhibition of the enzyme by the phosphonic acids of the chloroacetyl and chloropropyl analogues 2.1 and 2.2 respectively. Molecular modelling of the compounds on E. coli (PDB code: 2EGH) and P. falciparum (PDB code: 3AUA) DXR showed strong binding of the halogenated fosmidomycin analogues while the hybrids in the absence of docked NADPH showed minimum binding to the enzymes.
The relative suitability of knowledge paradigms to indigenous African resource management and their implications for environmental bioethics, environmental policy and food security
Authors: Agbor Ambang, Oscar Mbi
Type: thesis , text , Masters , M.Pharm
Description: Thesis (M.Pharm)--Rhodes University, Faculty of Pharmacy, Pharmacy, 2020.
Date Issued: 2020-04
A phenomenological investigation of the beginning therapist's experience of the first session of psychotherapy with the first patient
Authors: Allen, Jennifer Ann
Description: The aim of this project is to come to an understanding of how the situation of the first session of psychotherapy with the first patient is lived by the beginning therapist and what meaning this situation holds for him. The writer's interest in this phenomenon grew out of her own experience of this situation as a clinical Masters coursework student, an experience which was of important to the writer and meaningful still as a therapist in training. In dialogue with experienced therapists the importance of this situation was again made apparant. It was the opinion of these therapists that although for some the details of this experience had become dulled by time, what remained meaningful to them was that this experience was seen as the beginning of a project which remains important to them - they identified this situation as an important moment in the history of their development as psychotherapists. In the hope that the literature pertaining to psychotherapy would throw some light on this situation, the writer turned to a number of sources in this area to discover that no literature available to her elucidated this situation in a holistic manner. This led the writer to go back to the beginning therapists themselves so that they may speak for themselves of their experience of this situation. A phenomenological method of enquiry is implemented in this study as it renders the subject matter accessible to investigation, and allows it to reveal itself as it essentially is. This project is then an attempt to come to a general description of the beginning therapist's experience of the first session of psychotherapy with the first patient and thus to articulate the structure of the beginning therapist's lived situation (world) in this context. , Thesis (MA) -- Faculty of Humanities, Psychology, 1987
In silico analysis of plasmodium falciparum Hsp70-x for potential binding sites and hits
Authors: Amusengeri, Arnold
Type: text , Thesis , Masters , MSc
Description: Restricted access-thesis embargoed for 1 year - release date April 2019
Self-reports on the effectiveness of psychotherapy with therapists-in-training: an 18-month follow-up study at a psychology training clinic
Authors: Angus, Catherine Clare
Description: The purpose of this study is to ascertain whether the clients who make use of the services of the Psychology Clinic at Rhodes University perceive the masters students being trained at the Clinic as providing adequate psychotherapy. Using a sample of 18 clients, who underwent psychotherapy at the Rhodes Psychology Clinic during 1990, a follow-up study was conducted to ascertain the perceived success of that psychotherapy. Those variables most pertinent to the outcome of psychotherapy are examined. The study uses both qualitative and quantitative methodology and shows that, overall, 89% of the clients who participated in this study perceived the psychotherapy at the Rhodes Psychology Clinic to be satisfactory. The study also highlights those factors which were perceived to be negative in the psychotherapeutic equation and it is hoped that the findings can be beneficial in planning more efficient services for the Clinic in the future. , Thesis (MA) -- Faculty of Humanities, Psychology, 1993
Composition Portfolio
Authors: Appollis, Sylvester
Date: 201u
Description: Composition portfolio. , Thesis (MMus) -- Faculty of Humanities, Music and Musicology, 201u
Date Issued: 201u
Potential of the Gravel Filter Towers, Pilot-scale Filter system and Biochar/Clay adsorbents for Bio-Physicochemical remediation and Desalination of greywater
Authors: Bani, Siphumze
Description: Thesis embargoed until 2023 , Thesis (MSc) -- Faculty of Science, Rhodes University Biotechnology Innovation Centre, 2021
Contributions to the study of nonholonomic Riemannian manifolds
Authors: Barrett, Dennis Ian
Identifier: http://hdl.handle.net/10962/7554 , vital:21272 , DOI https://doi.org/10.21504/10962/7554
Description: In this thesis we consider nonholonomic Riemannian manifolds, and in particular, left- invariant nonholonomic Riemannian structures on Lie groups. These structures are closely related to mechanical systems with (positive definite) quadratic Lagrangians and nonholo- nomic constraints linear in velocities. In the first chapter, we review basic concepts of non- holonomic Riemannian geometry, including the left-invariant structures. We also examine the class of left-invariant structures with so-called Cartan-Schouten connections. The second chapter investigates the curvature of nonholonomic Riemannian manifolds and the Schouten and Wagner curvature tensors. The Schouten tensor is canonically associated to every non- holonomic Riemannian structure (in particular, we use it to define isometric invariants for structures on three-dimensional manifolds). By contrast, the Wagner tensor is not generally intrinsic, but can be used to characterise flat structures (i.e., those whose associated parallel transport is path-independent). The third chapter considers equivalence of nonholonomic Rie- mannian manifolds, particularly up to nonholonomic isometry. We also introduce the notion of a nonholonomic Riemannian submanifold, and investigate the conditions under which such a submanifold inherits its geometry from the enveloping space. The latter problem involves the concept of a geodesically invariant distribution, and we show it is also related to the curvature. In the last chapter we specialise to three-dimensional nonholonomic Riemannian manifolds. We consider the equivalence of such structures up to nonholonomic isometry and rescaling, and classify the left-invariant structures on the (three-dimensional) simply connected Lie groups. We also characterise the flat structures in three dimensions, and then classify the flat structures on the simply connected Lie groups. Lastly, we consider three typical examples of (left-invariant) nonholonomic Riemannian structures on three-dimensional Lie groups, two of which arise from problems in classical mechanics (viz., the Chaplygin problem and the Suslov problem). , Thesis (PhD) -- Faculty of Science, Mathematics (Pure and Applied), 2017
"Burnout" in children's home houseparents
Authors: Bath, Peter John
Description: Aimed at replicating the results of an American study into "Burnout" in Group Home houseparents, this research had the following aims: 1) To ascertain the validity and reliability of the instrument used in the original study and presented as a "useful measure of burnout". 2) To establish whether this line of research, within a highly problematic research field, can at present offer any guidelines in the resolution of the current staffing crisis faced by South African children's homes. 3} To describe more closely the burnout syndrome. 4) To study possible etiological factors within a local context. Sixty three houseparents completed questionaires and three independent measures of burnout were obtained. The results were regarded as having failed to replicate those of the original study. The reason for this was found to be the low validity of the original instrument. The main conclusion drawn was that the line of research adopted in the original study can offer only very tentative guidelines towards the resolution of the staffing crisis faced until such time as valid and reliable instruments to measure burnout have been developed. Many of the suggested relationships between situational variables and ones of personal characteristics were confirmed for the local population of houseparents. , Thesis (MSocSci) -- Faculty of Humanities, Psychology, 1983
The role of Stress Inducible Protein 1 (STI1) in the regulation of actin dynamics
Authors: Beckley, Samantha Joy
Description: Stress-inducible protein 1 (STI1) otherwise known as Hop (Hsp70/Hsp90 organising protein) is a highly conserved abundant co-chaperone of the Hsp70 and Hsp90 chaperones. STI1 acts as an adapter protein, where it regulates the transfer of protein substrates from Hsp70 to Hsp90 during the assembly of a number of chaperone-client protein complexes. The role of STI1 associating independently with non-chaperone proteins has become increasingly prominent. Recent data from colocalisation and co-sedimentation analyses in our laboratory suggested a direct interaction between STI1 and the cytoskeletal protein, actin. However, there was a lack of information on the motifs which mediated this interaction, as well as the exact role of STI1 in the regulation of cytoskeletal dynamics. Two putative actin binding motifs, DAYKKK (within the TPR2A domain) and a polyproline region (after the DP1 domain), were identified in mammalian STI1. Our data from in vitro interaction studies including surface plasmon resonance and high speed co-sedimentation assays suggested that both TPR1 and TPR2AB were required for the STI1-actin interaction, and peptides corresponding to either the DAYKKK or the polyproline motif, alone or in combination, could not block the STI1-actin interaction. Full length mSTI1 was shown to have ATPase activity and when combined with actin an increase in ATPase activity was seen. Ex vivo studies using STI1 knockdown shRNA HEK293T cells and non-targeting control shRNA HEK293T cells showed a change of F-actin morphology as well as reduction in levels of actin-binding proteins profilin, cofilin and tubulin in the STI1 knockdown cells. These data extend our understanding of the role of STI1 in regulating actin dynamics and may have implications for cell migration. , Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 2015
Biochemical characterisation and small molecule modulation of the interaction between two cytosolic Hsp70s from Trypanosoma brucei and potential co-chaperones
Authors: Bentley, Stephen John
Description: Expected release date-April 2019
A study of four-dimensional oscillator groups and the associated left-invariant control affine systems
Authors: Biggs, Rory
Type: thesis , text , Masters , MSc
Description: Thesis (MSc)--Rhodes University, Faculty of Science, Department of Mathematics, 2012
Neutral Atomic Hydrogen in Gravitationally Lensed Systems
Authors: Blecher, Tariq Dylan
Description: Thesis (PhD) -- Faculty of Law, Law, 2021
Diversified computational approaches for the identification of orthosteric drugs, allosteric modulators and unveiling drug resistance mechanisms: application to infectious diseases
Authors: Boateng, Rita Afriyie
Description: Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2022
Synthesis and in vitro biological evaluation of 2,3-substituted quinoline derivatives
Authors: Bokosi, Fostino Raphael Bentry
Description: The urgent need for new systemic pharmacological entities prompted us to report a library of 2,3-substituted quinoline derivatives. Considering the ubiquity of quinoline-containing compounds in pharmacologically active small molecules, synthesized 2,3-substituted quinoline derivatives were in vitro biologically evaluated for their potential antitubercular, antimalarial and antitrypanosomal activities. Quinoline scaffold was achieved by the Vilsmeier-Haack methodology, affording synthetically useful chloro and formyl substituents on C-2 and C-3 respectively. These two substituents acted as handles in expanding the chemical space around the quinoline ring. Target compounds were synthesized in six to seven steps, employing conventional synthetic organic protocols adapted from various literature. The final compounds were accessed in moderate to good yields. The structural identity of each compound was confirmed by common spectroscopic techniques. Aryl quinoline carboxamide derivatives 3.113 – 3.126 were isolated as rotamers, hence, Variable-Temperature Nuclear Magnetic Resonance (VT-NMR) was employed in resolving 1H splitting. At elevated temperature (~328 K); N-methylene carbons were not visible on 13C NMR due to signal line broadening effects. The presence of these nuclei in such cases was, however, supported by 2-dimensional NMR and high-resolution MS data. Most of the compounds achieved in this study displayed promising antimalarial activity against chloroquine-sensitive 3D7 strain of Plasmodium falciparum compared to antitrypanosomal activity against Trypanosoma brucei brucei 427 strain. In particular, compounds 3.80 and 3.108 showed superior activity against chloroquine-sensitive 3D7 P. falciparum strain with IC50 values < 1 μM. More importantly, most of the compounds were non-toxic as determined by HeLa cells, indicating their selectivity towards the parasites. Exploring the space provided on the quinoline scaffold revealed that methoxy incorporation on C-2 is very critical in enhancing antimalarial activity of this class of quinoline compounds. The preliminary SAR of compounds 3.57 – 3.72 showed that compounds containing the 3-cinnamate exhibited enhanced antimalarial activity compared to 2 and 4-cinnamates. Finally, benzamide compounds 3.113 − 3.126 showed poor activity against Mycobacterium tuberculosis H37Rv strain with only compounds 3.113, 3.117 – 3.120 and 3.126 showing appreciable MIC90 values in the range of 40 – 85 μM. , Thesis (MSc) -- Faculty of Science, Chemistry, 2020


What's with all the #@%$&%# cussing?
And the college student when she realized it was close to impossible to bring her grade up to passing.
As well as the other college student who suddenly found himself pulled over by a police officer and was driving without a license.
And a citizen of Laketown when she saw Smaug the dragon flying towards them in The Hobbit.
And countless others all across this country, both in real life and the fake one.
The fake one. Television. Movies. Radio.
The fake life. The fake world.
Smith goes on to ask if someone was walking down the street, would they really curse to the extent that somebody on a TV show would?
The fake life. The fake world. The hyperreal world.
So what does any of this have to do with people saying they are f*****?
Fictional people say it. Real people say it.
Dr. Van Roberts, associate professor of communication at The W, has his own opinion.
Hold on now. Isn't that the exact opposite of what Smith said earlier?
The answer is both, depending on how it is viewed.
Roberts sees kids cursing more today because cursing is more common in movies or on television, while Smith attributes it more to desensitization.
In other words, it loses its shock value.
So TV is making people curse more today than ever before, right? Well, maybe not.
It all comes back to hyperreality. People curse because they hear the words on TV. TV curses more as a way to stay edgy and to seem more realistic. People see TV as being realistic and allow their lives to mimic that.
It's the mirrors all over again. The chicken and the egg. Television. Movies. Radio.
Three forms of media and popular culture. Three different ways for cursing to become ingrained into people's minds. Cursing has become more prevalent in today's society, but does that really mean it's become more acceptable?
Cursing is everywhere. That point has been driven home fairly well now, but that still doesn't quite explain why it happens so often.
There's nothing wrong with cursing, according to Roberts, as long as you pick judiciously when to use it.
Cursing shows a lack of imagination?
Newer PostSpectator Sound-Off: What are your plans for Christmas Break?


text:
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Mick Fleetwood Becomes Third Member of Fleetwood Mac to Sell Song Catalog
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Jem Aswad
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BMG announced that it has acquired "outright" Fleetwood Mac co-founder Mick Fleetwood's interests in the band's recordings.
The deal gives BMG Fleetwood's royalty interest in over 300 recordings, including the hits including "Dreams" — which enjoyed a massive resurgence due to recent popularity on TikTok — "The Chain," "Go Your Own Way" and "Landslide" from albums including the multiplatinum albums "Fleetwood Mac," "Rumours," "Tango in the Night" and others. It includes Fleetwood's interest in all of their recorded work apart from their first two albums.
While Fleetwood did not write any of the above songs and has relatively few songwriting credits, his recorded-music rights as bandmember and drummer on the tracks yield him royalties connected to album sales, downloads and streaming.
BMG already has a relationship with the band, re-releasing its classic 1970 album "And Play on" and the theatrical, record and mediabook release of Mick Fleetwood & Friends, 2020's tribute event to legendary guitarist Peter Green and the early years of the band. Fleetwood and bassist John McVie cofounded the band with Green in 1967; its most commercially successful lineup formed when Stevie Nicks and Lindsey Buckingham — both of whom recently sold their publishing rights for undisclosed amounts, although Nicks' is reported to be $100 million — joined in 1975.
BMG CEO Hartwig Masuch said, "Mick Fleetwood is the bedrock of one of the greatest bands in rock, he has a unique talent to bring together musicians of all genres and of course he is one of rock's greatest drummers. BMG is proud to represent his greatest work and excited about the forthcoming launch of Mick Fleetwood & Friends."
Mick Fleetwood said, "This is a wonderfully inspiring marriage between two creative partners that understand all aspects of the business. Foremost, BMG understands the artistry and puts the artist first. If this partnership is any indication of my past, and now future, working relationship with BMG, it's that they truly 'get it'."
The sale of Mick Fleetwood's recorded interests was brokered by his manager Carl Stubner of Shelter Music Group. Said Stubner: "For over 50 years Mick's works continue to be introduced to legions of new fans while BMG continues to ensure its artists are paid their fair share. In an industry, not always known to look after its iconic artists, BMG continues to maximize their income streams."
BMG EVP Group Strategy and M&A Justus Haerder said, "This acquisition highlights the value of timeless recordings in a streaming market which is increasingly benefitting established rather than newer artists. While recent acquisition activity in the music market has focused on music publishing, this is a pure recorded investment which will get the full benefit of streaming growth. Catalogues such as Fleetwood Mac's which connect with every generation are benefiting disproportionately from that growth."
Fleetwood Mac,

redpajama_set_name: RedPajamaCommonCrawl


UPDATED, 6:07 PM: Van Halen also will appear on Ellen on April 2.
two nights. The gig, set for March 30 and airing that night and the next, will mark Van Halen's first U.S. television appearance with once and current singer David Lee Roth. Will we get a glimpse of the revered/reviled "Diamond Dave" persona that helped launch the group to megastardom and eventually contributed to its demise?
The revived band will be promoting its 38-date North American tour, which kicks off in earnest July 5 in Auburn, WA, and also has a new record out next week. Tokyo Dome Live In Concert is Van Halen's first concert album with Roth, who left the group in 1985 and rejoined 22 years later. The Kimmel date will be a warmup for the tour — reminiscent of the Los Angeles-bred band's playing a free show at the Forum in advance of its Roth-reunion jaunt in 2007.


text:
Isomer II
Objective 1: Defeat the boss
Objective 2: Capture enemy Command Center
Recommended Echelon(s): AR/SMG (x2)
Objective 1
So, unlike EX, normal is a lot more straightforward. There's only one real route we need to take and it's the same for both objectives. The end's different, since we have a little extra to do on objective two, but that's it. For this objective though, all we need to do is use the one console at the bottom of the map, and then engage the Nyto Isomer White.
To start us off, we want our combat echelon out and ready. Use it to take out the Isomer to the left of your Command Center, then deploy a second combat echelon. We're gonna be leaving that second echelon on our Command Center so we have some defense if needed.
On turn two, swap and resupply our first echelon, then swap back. It's time to move out. We're gonna head down from that closed Heliport to the Radar Tower, which will despawn one of the Manticores from the map. Move on to the closed Heliport to the left of the Radar Tower and take it.
For turn three, move down to the Supply node and use it to resupply. We can now go and use the console to open up the gate to the enemy Command Center and the boss. Open it and get ready to fight the boss.
On turn four, we can go straight to the boss and engage her.
Nyto Isomer White
So for this boss, she'll do a lot of shit that doesn't really matter, since it's a debuff. Her main thing is that she has failed Isomers coming in constantly, that you need to take care of before they stun you with an EMP. For these, once they start getting close to you, retarget your ARs so they focus fire them.
She does a lot more than that, though. Every so often, she'll pick one of your T-Dolls and put them into a stasis. She will then summon a clone of herself that will start shooting you. The clone has a taunt effect so all your T-Dolls will focus it down. Killing the clone will end the stasis. These clones, I believe, also give an HP shield to all enemies on the battlefield at the time. Fun. Oh, and the clones also have different targeting, because they change type of weapons depending on what T-Doll gets hit with the stasis!
Oh, but that's not it, she also has skills. At around every quarter of her HP, she'll use her skill called Epiphyllum Illusion, which will, once again, stasis one of your T-Dolls. However, now there's multiple clones with HP shielding to cut through. The amount of clones she spawns is equal to how many T-Dolls you have left on the field. Five T-Dolls up? Five clones spawned. This is a hard DPS check, since if you don't kill the clones fast enough (within 15 seconds), the stasis will become permanent for the battle, and there now will be a clone that is invulnerable and will stay there for the rest of the fight. So...DPS hard and fast.
Once you've beaten her, you'll finish the map.
So, this is the exact same as the first objective, but with added steps at the end. Wow, cool. The extra steps are using another console, and then baiting the Nyto so you don't need to fight her. That's it. I'll copy some of the objective one stuff and add more just for a guide, though.
To start us off, we want our combat echelon out and ready. Use it to take out the Isomer to the left of your Command Center, then deploy a second combat echelon.
For turn three, move down to the Supply node and use it to resupply. At this point, you may have been accosted by a Scout echelon near your Command Center. Now's a good time to take it out if you have been. If not, well, that's great. Either way, move your second echelon to the left and deploy a dummy echelon. We'll be using it for bait and extra AP. You could use your second echelon for that, but this way is safer and uses less resources. Make sure you swap your combat echelon back to your Command Center.
On turn four, move to the console and use it. Open both gates that can be accessed from the console. Stay outside of Nyto Isomer White's alert radius as you move your first echelon up towards the other console. You can access it on turn five, which should open the gate that goes to your own Command Center. The Nyto will move towards your dummy echelon, letting you take the Command Center on turn six, which clears the objective and this map.
Videos of me clearing this map


text:
Dear Friends!
It gives me great pleasure to welcome all the participants and guests of the On the Edge Film Festival '2017, a project unprecedented for our country. Over the years, the festival has not only become a place where filmmakers from Russia and abroad can meet and share their work, but also an important outlet for the proactive islanders' creativity that provides excellent educational opportunities.
A unique atmosphere has been created here, allowing artists and their audiences to communicate with each other freely, to address the most vital concerns, and to seek solutions. I am certain that this year's edition will impress the locals and visitors alike, and yield a lot of valuable insights.
The festival program boasts over 70 films from all over the globe, as well as music and theatrical shows. The island's youngsters are in for an especially exciting ride: more than mere spectators, this year they will be able to make, under their mentors' supervision, their own films, both animated and live action.
Particular emphasis will be placed on the Sakhalin Oblast itself, which is celebrating its 70th anniversary as a territorial unit. As they narrate the history of the region through its natives' journeys, the workshop participants will create an unusual guide to the central city of Sakhalin. It is of no small importance that these projects, as well as many others, both cultural and social, will live on beyond the festival. We will always support wholeheartedly all initiatives aimed at developing Sakhalin and the Kuril Islands, and preserving the history and authenticity of our distinctive region where European and Asian cultural traditions intersect.
I wish you the best of luck, and hope you enjoy the many productive conversations you will have at the Sakhalin Film Festival.
Oleg Kozhemyako,
Governor of the Sakhalin Oblast
Let me open with a paradox: the festival is ready to go; the guests have been invited; the films have arrived from all over the world; and yet, we still don't know what On the Edge '2017 will look like. A year later, our team is back at the festival, and over this year Sakhalin has changed dramatically and so has cinema, and so have we.
«You could not step twice into the same river» must be the wisest thought in the history of humankind. Seemingly crystal clear at first blush, the saying seems to posit that all things are permanently in flux, and when we return somewhere the place is never the same. However, a more radical interpretation is possible, too: you can't go home again. «Actually, Heraclites' principle asserts that at any given moment we are in the river already,» wrote Merab Mamardashvili. We can't step into the river twice or even once, because we are, ourselves, part of a mercurial flow, which we cannot be separate from to «linger on the shore» or «choose the right moment.» Difficult though it is, the situation is also a fertile one, because the invisible drift, time and again, carries our plans and ideas to some previously unfathomable destination.
So, what's going to be different about this year's On the Edge? We are sticking to the same through lines: East vs. West; attention to the neighboring countries; the interplay between center and periphery; and orientation toward the kind of accessible filmmaking that requires no special expertise. The through lines might be the same, but the shapes they form have been altered, and it seems that our island is in dire need of a remapping. While in the past Russian selections amounted to, roughly, one half of the program, finding their reflections, as it were, in the mirror of Asian cinema, the current perspective is much more global. There is but one fully Russian title in competition (but what a title it is!). Alongside various offerings from Japan, South Korea, and India, this year's slate covers Bulgaria, the Czech Republic, France, Argentina, and Georgia as well. The cinema of Southeast Asia is still markedly present, yet the theme of one's birthplace «small Motherland» in Russian as the place we always leave and inevitably come back to, has now moved to the forefront. As it turns out, this theme is universal for all countries and continents.
Our program of festival hits formerly known as «The Main Things» (Samoe Glavnoe) is now called «How to Watch Movies.» Along with the name, the presentation and angle have changed as well. The buzziest screenings will now be followed by lectures, discussions, and panels. The sidebar no longer claims to pick the cream of the crop previously screened at other festivals; evident masterpieces such as «Paterson» and «The Other Side of Hope» will be interspersed with genre filmmaking and that perennial audience favorite, acting tours de force. Learning how to watch movies means not only mastering the subtleties but also keeping an open mind.
Another novelty is the «Growing Pains» program (Trudnosti Vzrosleniya), in which the world's greatest filmmakers tackle the issues of that most crucial and vulnerable time in man's life coming of age. We hope this subject will be at the root of another large-scale project of ours, but let's not get ahead of ourselves.
Last but not least, I'd like to point out that the «Sakhalin Cinema» program has never been as vast, diverse, or intriguing. Following the local premiere, Sakhalin native Dmitry Moiseev will take his «In the Embrace of the Sea» straight to the international arena. We hope some credit for his success is at least partially ours.
Aleksey Medvedev,
Programme Director


text:
La 16 édition des Championnats ibéro-américains d'athlétisme (en espagnol : XVI Campeonato Iberoamericano de Atletismo) se déroule du 1 au  au Stade Estadio Ícaro de Castro Melo de São Paulo, au Brésil. La compétition réunit les athlètes des pays de la zone Ibéro-Amérique, ainsi que l'Espagne, le Portugal et les nations hispanophones et lusophones d'Afrique.

Participants

Résultats

Hommes

Femmes

Liens externes
 Site officiel

Notes et références

2014
Événement sportif international au Brésil
Compétition d'athlétisme à São Paulo
Sport au Brésil en 2014
Athlétisme en août 2014

redpajama_set_name: RedPajamaWikipedia


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ATHREYA LAHIRI MEASURE THEORY PDF
He is a fellow of the Institute of Mathematical Statistics, a fellow of the American Statistical Association, and an elected member of the International Statistical Institute. Carlos Llosa is currently reading it Sep 26, Ronald Lett rated it liked it May 12, It leads them to think only in terms of the Lebesgue measure on the real line and to believe that wthreya theory is intimately tied to the topology of the real line. Debomitra Sett marked it as to-read Feb 17, Thanks for telling us about the problem. Lahiri No preview available — Abdul William marked it as to-read Feb 17, It then treats thoroughly the laws of large numbers including renewal theory and ergodic theorems with applications and then weak convergence of probability distributions, characteristic functions, the Levy-Cramer continuity theorem and theoory central limit theorem as well as stable laws. Sam marked it as to-read Mar 04, Books by Krishna B. This book is not yet featured on Listopia.
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The final prices may differ from the prices shown due to specifics of VAT rules About this Textbook This is a graduate level textbook on measure theory and probability theory. The book can be used as a text for a two semester sequence of courses in measure theory and probability theory, with an option to include supplemental material on stochastic processes and special topics. It is intended primarily for first year Ph. Prerequisites are kept to the minimal level of an understanding of basic real analysis concepts such as limits, continuity, differentiability, Riemann integration, and convergence of sequences and series. A review of this material is included in the appendix. The book starts with an informal introduction that provides some heuristics into the abstract concepts of measure and integration theory, which are then rigorously developed.
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Kagazshura Benjamin Hermalin added it Aug 09, Part II chapters provides full coverage of standard graduate level probability theory. It leads them to think only in terms athreta the Lebesgue measure on the real line and to believe that measure theory is intimately tied to the topology of the real line. BookDB marked it as to-read Sep 20, Prerequisites are kept to the minimal level of an understanding of basic real analysis concepts such as limits, continuity, meausre, Riemann integration, and convergence of sequences and series. There are no discussion topics on this book yet. Athreya, Soumendra N. Athreya is a professor at the departments of mathematics and statistics and a Distinguished Professor in the College of Liberal Arts and Sciences at the Iowa State University. The book can be used as a text for a two semester sequence of courses in measure theory and probability theory, with an option to include supplemental material on stochastic processes and special topics.
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