text:
Incidence of lymph node metastasis in early-stage low-grade serous ovarian cancer: a systematic review
http://orcid.org/0000-0001-9395-0627David Viveros-Carreño1,2,
http://orcid.org/0000-0002-5472-4093Juliana Rodriguez1,3 and
http://orcid.org/0000-0003-0093-0438Rene Pareja1,4
1 Department of Gynecologic Oncology, Instituto Nacional de Cancerología, Bogotá, Colombia
2 Gynecologic Oncology, Clínica Universitaria Colombia and Clínica Los Nogales, Bogotá, Colombia
3 Department of Gynecology and Obstetrics, section of Gynecologic Oncology, Fundación Santa Fe de Bogotá, Bogotá, Colombia
4 Gynecologic Oncology, Clinica ASTORGA, Medellin, Colombia
Correspondence to Dr David Viveros-Carreño, Gynecologic Oncology, Instituto Nacional de Cancerología, Bogota, Colombia; dviverosc{at}gmail.com
Objective The objective of this systematic review was to assess the incidence of lymph node metastasis in patients with clinically presumed early-stage low-grade serous ovarian cancer that underwent primary surgical treatment.
Methods This study was registered in PROSPERO (CRD42022308923). A systematic literature review was conducted following the Meta-analyses Of Observational Studies in Epidemiology (MOOSE) checklist. PubMed/MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Ovid, and Scopus databases were searched since inception and up to March 2022. The inclusion criteria were: pathological confirmation of low-grade serous ovarian cancer (clinically presumed FIGO 2014 stages I-IIA at time of surgery) that underwent primary surgical treatment, including pelvic and/or para-aortic lymph node dissection.
Results The search identified 3763 articles; 59 were considered potentially eligible after removing duplicates, and eight studies finally met the selection criteria. In total, 35 of 277 (12.6%) patients had lymph node metastasis, and only four studies reported upstaging due to lymph node metastasis in 16 of 153 (10.5%) patients. None of the eight studies included reported the rate of complications or complications specifically for the subgroup of patients with early-stage low-grade tumors.
Conclusion In patients with early-stage low-grade serous ovarian cancer, lymph node assessment should be discussed when counseling for primary surgical staging.
cystadenocarcinoma, serous
All data relevant to the study are included in the article or uploaded as supplementary information.
http://dx.doi.org/10.1136/ijgc-2022-003618
The rate of positive lymph nodes in patients with clinically presumed early-stage low-grade serous ovarian cancer was 12.6%.
The upstaging rate due to lymph node metastasis alone was 10.5%.
None of the studies included report specific complications of the lymph node dissection.
WHAT IS ALREADY KNOWN ON THIS TOPIC
Low-grade epithelial ovarian tumors have a smaller risk of lymph node metastasis compared with high-grade epithelial tumors. However, the risk differs among histological subtypes (endometrioid, mucinous, or serous) and could be higher for low-grade serous tumors compared with the other low-grade epithelial tumors.
WHAT THIS STUDY ADDS
The risk of lymph node metastasis of low-grade serous tumors is higher than that previously reported for other low-grade epithelial tumors and the upstaging rate due to lymph node metastasis alone is higher than 10%.
HOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICY
The reported rate of lymph node involvement and the impact of its identification in adjuvant management decisions may justify the performance of lymph node assessment; however, the effect of this finding on oncological outcomes has not been demonstrated and given the rarity of this tumor is highly unlikely to be evaluated in prospective trials.
Ovarian cancer is the eighth most common cancer among women worldwide, with 6.6 cases per 1 00 000 women and 313 959 new cases reported in GLOBOCAN 2020. It has a disproportionately high mortality rate of 4.2 cases per 100.000 women,1 and only about a third of the patients present with early-stage disease.2 Primary surgical treatment is the preferred therapy for this population.
Low-grade serous ovarian cancer represents about 10% of epithelial ovarian cancer cases.3 Although there are differences with high-grade serous ovarian cancer in molecular biology, clinic characteristics, and prognosis, these patients are treated similarly. Low-grade serous ovarian cancer is considered relatively insensitive to systemic chemotherapy; however, it remains a standard treatment in advanced disease after maximum surgical effort.4 5
The indication for lymph node dissection in ovarian cancer patients has been debated during the last several years for high-grade epithelial ovarian cancer. Recently a prospective trial6 demonstrated no benefit of systematic lymphadenectomy in advanced disease with macroscopically complete resection and clinically apparent normal lymph nodes. On the other hand, for clinical early stages (International Federation of Gynecology and Obstetrics (FIGO) 2014 stage I-IIA) comprehensive surgical staging, including systematic bilateral pelvic and para-aortic lymphadenectomy up to the renal veins, still could have a crucial role due to the occult lymph node metastasis in apparent early-stage disease of nearly 15%7 and the subsequent change in the adjuvant treatment.5 8 9
The incidence of lymph node metastasis may change according to histologic subtype and grading. A previous report showed that the incidence is only 2.9% in low-grade early-stage epithelial ovarian cancer.10 As the incidence for low-grade serous ovarian cancer could be higher than for low-grade endometrioid or mucinous histological types, the objective of this systematic review was to assess the incidence of lymph node metastasis in patients with clinically apparent early-stage low-grade serous ovarian cancer who underwent primary surgical treatment.
The Meta-analyses Of Observational Studies in Epidemiology (MOOSE) checklist was used to conduct this systematic review and the protocol was registered in PROSPERO (CRD42022308923). MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Ovid, and Scopus databases were searched since inception and up to March 2022. The search strategy is reported in the Online supplemental file 1. We also searched the reference lists of eligible studies and used forward citation tracking with Google Scholar to identify further eligible manuscripts. Similar methodology has been reported by the authors previously.11
[ijgc-2022-003618supp001.pdf]
All types of studies published in the English language literature were included, except for case reports, abstracts, commentaries, and unpublished studies. The inclusion criteria were pathologically confirmed low-grade serous ovarian cancer (clinically presumed FIGO 2014 stages I-IIA at time of surgery) that underwent primary surgical treatment, including pelvic and/or para-aortic lymph node dissection. Any surgical route (laparotomy or minimally invasive surgery) was allowed. Only grade 1 tumors were considered if the tumor grade was specified, given significant variations in their classification into low- and high-grade for grade 2 tumors. For studies that did not specified tumor grade, all low-grade tumors were included.12Criteria for exclusion were patients under 18 years of age, neoadjuvant chemotherapy administration, and evidence of lymph node metastasis, either on pre-operative images, or at the time of surgery.
When two or more articles were published by the same authors or using the same data source, only the most recent article was included. The measured outcomes were the incidence of pelvic and/or para-aortic lymph node metastasis as defined by the authors, the rate of upstaging exclusively due to lymph node involvement, and the rate of complications associated with lymph node dissection as defined by the authors. Studies not reporting the number of resected nodes could be included in the review, and for studies reporting the number of lymph nodes resected at least 10 nodes per patient had to be resected to be included in the review.
Two authors (JR, DV-C) independently assessed all titles and abstracts of records retrieved from the search strategy for inclusion. The final selection of studies for inclusion was undertaken independently by three authors (RP, JR, DV-C) and any disagreement was resolved through discussion. We designed a form to extract data, which was pilot tested. Two authors (JR, DV-C) extracted the data independently using the form for eligible studies. Any disagreement about extracted data was resolved through discussion until a consensus was reached.
The information was presented as medians or means (according to its normal distribution) and percentages with absolute counts, if it was a quantitative or qualitative variable, respectively. The descriptive statistics were performed in SPSS 2.0. According to local regulations, no institutional review board agreement was required for this type of study. Ethical approval was not required as only data from previously published studies were retrieved and analyzed. No new data are presented.
The search identified 3763 articles; after duplicates were removed, 1874 articles were evaluated, and the title and abstract screening of these references identified 59 studies as potentially eligible for this review. The full-text screening excluded 51 studies, and eight studies finally met the selection criteria. Four studies were excluded because they did not provide information according to histological types, one was a literature review and did not have new patients reported, four did not include low-grade tumors, and 42 did not provide separate information for early-stage low-grade serous tumors (Figure 1 and Online supplemental file 2).
PRISMA flow diagram for study selection.
The total number of patients included in the eight studies was 2964, but only 277 patients had early-stage low-grade serous tumors and were considered for the analysis. Seven studies were retrospective series13–19 and one study was a population-based study.20 The accrual time was from 1975 up to 2018. Three studies included only FIGO stage I tumors14 19 20 and five included FIGO stage I and II tumors.13 15 16 We selected only patients with tumors up to FIGO stage IIA tumors for the review. Tumor grade was reported and classified as low grade in five studies13–15 17 18 and reported as grade 1 serous tumors in three studies.16 19 20
The details about the performed surgeries were not described in three studies,15 17 20 it was described as staging surgery or primary surgery in three studies,16 18 19 as a surgery that included hysterectomy, bilateral salpingo-oophorectomy, peritoneal random peritoneal biopsies, and omentectomy in one study,13 and as bilateral salpingo-oophorectomy (97.5%), hysterectomy (82.8%), omentectomy (98.8%), and appendectomy (68.1%) in one study.14 Two studies13 14 included patients with primary surgery and reclassification surgery; four included only primary surgery treatment,15 16 18 19 and it was not reported in two of the studies.17 20 Details about included studies are provided in Table 1. Given the nature of the studies and the intervention, with only single-arm studies, we did not evaluate the risk of bias for included studies as this would not provide reliable information.
Major characteristics of studies included in the systematic review
Six studies reported pelvic and para-aortic lymph node dissection,13–16 18 19 one20 did not report specifically if pelvic and para-aortic dissection was performed, and one17 reported some patients with pelvic and others with pelvic and para-aortic dissection. Two studies included the number of resected lymph nodes; one reported for inclusion a minimum of 10 pelvic and 10 para-aortic nodes,14 and one at least 20 nodes in total.20 Five studies reported the median number of resected nodes, although three studies14 16 19 reported data only for the complete cohort of included patients and not independent information on early stages. The median number of resected nodes were 45,14 19 69,16 27,20 and 41.18
In total, 35 (12.6%) of 277 patients had lymph node metastasis. All studies reported at least one case of lymph node involvement, and the location was reported only in three studies,13 17 19 one patient with pelvic and para-aortic involvement in one study, 14 of 14 patients with pelvic and 4 of 14 patients with para-aortic metastasis in the second study; and in the third study four only pelvic and eight both pelvic and para-aortic region. The rate of lymph node metastasis for each study ranged from 2.7%13 to 25%.18 Three studies14 17 19 reported the number of patients upstaged exclusively because of lymph node metastasis. Of 153 patients, 25 (16.3%) had lymph node metastasis and 16 (10.5%) were upstaged only due to lymph node involvement. Unfortunately, none of the eight included studies reported the rate of complications or complications specifically for the subgroup of interest of patients with early-stage low-grade serous tumors. Details about lymph node procedures are provided in Table 2.
Lymph node procedures and pathology report.
According to our protocol, we did two subgroup analyses. For the first analysis, excluding the population-based study, in seven studies13–19 210 patients were reported and 29 patients had confirmed lymph node metastasis (13.8%). When only patients with stage I were analyzed, 183 patients from three studies14 19 20 were included and 24 (13.1%) had lymph node metastasis. The results of the subgroup analyses showed no relevant effect on the general results.
Summary of Main Results
In our review, the overall rate of lymph node metastasis in patients with early-stage low-grade serous ovarian cancer was 12.6%. Patients were upstaged exclusively because of lymph node metastasis in 10.5% of cases. The rate of involvement in this group of patients may justify lymphadenectomy in primary surgical management.
Results in the Context of Published Literature
For all low-grade early-stage epithelial tumors, the incidence of lymph node metastasis has been reported previously in less than 3% of cases,10 20 unlike high-grade tumors where a lymph node metastasis rate of 10% or higher7 13 20 has been reported. In high-grade tumors, a plausible impact on oncologic prognosis21 is assumed by the lymph node dissection and the recommendation of systematic lymphadenectomy in clinical early stages as part of the primary surgical treatment in international guidelines is recommended.5 9
The ovarian epithelial tumors are heterogeneous, in mucinous and endometrioid tumors molecular and clinical behavior can differ from that of serous tumors.22 23 These differences are reflected among others on the risk of lymph node metastasis; for expansile (low-grade) mucinous tumors the rate of involvement could be nearly zero24 25 and it is less than 2% for low-grade endometrioid tumors.14 20 However, this risk is up to 10% for low-grade serous tumors.
The relevance of lymph node metastasis identification is associated with the requirement for adjuvant treatment and the oncological prognosis of patients. Guidelines5 9 recommend abstaining from adjuvant chemotherapy in patients with early stages (FIGO 2014 IA-IB) of low-grade serous ovarian cancer but recommend using combined systemic chemotherapy in cases of lymph node metastasis or if other advanced-stage features are present (FIGO 2014 IC-IV stage). Lymph node metastasis in advanced low-grade epithelial ovarian tumors is frequent with involvement in more than 70% of patients.15 18 However, it has been suggested that the lymph node dissection of microscopic disease has no impact on overall survival or progression-free survival in this population.15 The reporting of only early stages is limited in the literature; most studies report all low-grade early-stage tumors together or with all stages, and the risk of lymph node metastasis could have been underestimated previously.
Among the most relevant outcomes remains the rate of upstaging exclusively due to lymph node metastasis as a justification for the procedure; in our review it was 10.5%, whereas a previous systematic review that assessed the upstaging rate of the procedures that are performed in the primary surgical treatment of patients with epithelial ovarian cancer found that the upstaging rate for hysterectomy, omentectomy, peritoneal biopsies, appendectomy, and cytology did not exceed 10%.26
Unfortunately, in our review the studies included did not specifically report adverse events associated with lymphadenectomy; however, it is well known even from prospective randomized trials that lymph node dissection raises the risk of complications related to the surgery as evidenced by higher median blood loss, requirement for transfusions, intensive care support, higher infections, and reintervention rates.6 27
The main strength of our review is the rigorous process for data collection, and we have a pre-registered protocol with specified selection criteria and a rigorous process for data analysis. Our review is limited for several reasons. The clinical heterogeneity of the studies must be highlighted as we included case series studies and a population database study. The retrospective nature of all studies included in the review, with potential selection and publication bias, and the relatively small number of patients included in the results given the limited report of this specifical population, are limiting factors, particularly since we did not have information from most studies for adverse events, for upstaging exclusively for lymph node metastasis, and lymph node metastasis location. There was no central pathology review, surgical quality report beyond lymph node count for all studies, or complete information about pre-operative imaging studies. As we limited the search to published data in the English language, we could have missed some relevant references published in other languages, and as the studies were conducted over a long period, there could be performance bias.
Implications for Practice and Future Research
This systematic review confirms that the risk of lymph node metastasis for early-stage low-grade serous ovarian cancer is different than for other low-grade epithelial tumors. As the identification of lymph node involvement will change the recommendation of adjuvant chemotherapy, lymphadenectomy should be recommended. We encourage collection of prospective information in this population with subsequent data analysis according to the tumor type for future publications.
Given the rate of lymph node metastasis in clinically presumed early-stage low-grade serous ovarian cancer and the impact of its identification on adjuvant treatment decisions, lymph node assessment should be considered as part of primary surgical staging.
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Contributors DV-C: conceptualization, investigation, methodology, writing - original draft, writing - review, editing and responsible for the overall content as guarantor. JR: data curation, formal analysis, investigation, methodology, writing - review, and editing. RP: conceptualization, methodology, formal analysis, writing - review and editing, supervision.


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Snakes on flags.
What's up with the Gadsden flag? A free episode of Electable's "No Dumb Questions" series.
Understanding exactly how the government works is the first step towards making it more responsive and inclusive. That's why we started the Electable "No Dumb Questions" series.
We'll help you grow your confidence in this area so you feel confident running for office yourself or helping other women in your community run. We are all learning together, and Rule #1 at Electable is that there are no dumb questions.
Have you seen that hard-to-miss yellow flag with the symbol of a snake and the words "Don't tread on me" written in bold letters hanging from cars, houses or businesses in your area? What is it and what does it mean?
In this free episode of "No Dumb Questions," we dive into the history and meaning of the Gadsden flag. In this video, you'll learn:
Who designed the flag and when
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A funny thing seems to happen with backyard veggie gardens –either they don't yield much or you end up with an over abundance of zucchini and cherry tomatoes. This year, if you're experiencing the latter, don't worry, you are not alone. This is actually a relatively common problem that many home gardeners will face.
With that in mind, eieihome.com is sharing 5 things you can do with extra garden vegetables to ensure that absolutely nothing goes to waste.
Help out friends and family: Vegetables are the most important foods for human health, and we all know that health is wealth so why not spread the wealth to those you care about most, or foster new bonds with neighbours by offering up some of your excess produce.
Help those in need: There is probably no greater thing you can do with your extra produce than helping things in need. Local institutions such as the North York Harvest and Ontario Vegetarian Food Bank are two great options that will get your extra food into the hands of people who need it most. You can also consider giving some produce away to local institutions, or even making a posting on a classified site such as Kijiji or Craigslist.
Can them: Canning is an increasingly popular practice to preserve produce, especially with items such as tomatoes which can be used to create sauces. Although canning can be a safe and effective practice when done correctly, precautions must be taken. Have a look at the following Government of Canada resource to ensure you are doing it right.
Blanch and Freeze Them: Freezing is probably what most of you were already thinking, but storing certain vegetables in an optimal way may also require blanching (briefly boiling before freezing). Have a look at the following resource to learn how to blanch before freezing and why it is so important to do so.
Try a new recipe: If options #1-4 have been exhausted or just don't appeal to you, the best advice I can give you is to use whatever excess you have in creative ways. Google up fun and exciting vegetable-based recipes that you might not otherwise consider making and eat until your heart's content.
Following these five tips will help ensure that your extra veggies are being utilized to the fullest and that not a single one of those delectable gems goes to waste.


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Evolution of Phishing Attacks During the Pandemic
Brad SlavinCEO of DuoCircle LLC
Cyber-attacks involving phishing aren't a new phenomenon. However, during the COVID-19 pandemic cybercriminals took advantage of the global panic and disruption to launch dedicated phishing attacks on businesses. This article discusses the evolution of these attacks in the last year.
The COVID-19 pandemic was a situation that no organization could have anticipated. Cyber intruders took this opportunity to spread fake news and use phishing techniques to gain remote access to organizations' networks. Since businesses were more concerned about business continuity and had vulnerable mitigation plans, malicious actors adapted to the remote work and telecommunicating realities and impersonated trusted tech platforms. For instance, Zoom, Google Meet and Skype users were some of the most popular targets of the manipulative cybercrime.
Phishing attacks in statistics
Cyber attackers used phishing to trick victims and steal their financial information or other sensitive data using emails that contain malware or backdoors. Threat actors used spoofed websites that closely resembled original websites and tricked people into giving away login credentials. The work from home culture made phishing a more lucrative opportunity for the threat actors. The following graph represents the increase in spoofed websites visited between February and March.
Why the pandemic era witnessed a rise in phishing emails: motives behind the attacks
Phishing is one of the most widely used social engineering techniques due to its ease of implementation and higher success rate for malicious actors. Intruders used such phishing techniques during the pandemic, mainly for financial fraud or credential harvesting, as discussed below:
Threat actors usually demanded a one-time payment from targets claiming that payers will get a reward in return for charity to other organizations. Such campaigns also asked users for their card credentials or bank details and stored this sensitive information for future use. In addition to card details for payment, cybercriminals also sell the information on the dark web to other cybercriminals with similar intentions. They gained bank details through:
Formjacking, a type of cyber skimming
Scams that asked for user details
Spoofed websites that resembled original banking websites
Breached database containing financial information
Credential harvesting
Usernames, passwords and other credentials are readily available on the dark web, and malicious actors share or sell such sensitive information for money. The buyer can use this information for initiating attacks on targeted victims or may resell the data. This information is used primarily for financial fraud or theft of intellectual property. Since businesses have identified and started mitigating that credential phishing has been evolving amid COVID-19, attackers are now using content phishing for attacks.
What were the types of phishing techniques used?
A single technique won't be applicable for all kinds of cyberattacks, and adversaries are well aware of this. Initially, they study the target and articulate various attack strategies based on the target's type and cybersecurity defense. Amid the pandemic, there are three main types of phishing techniques that malicious actors employed:
General: An indiscriminate phishing attack in which many random victims are targeted, and unsuspecting users who aren't careful enough end up losing any crucial information they provide.
Semi-targeted phishing: Such attacks are generally well-planned and occur against a group of people or an organization's employees who aren't expected to have enough information on the modus operandi of how malicious actors employ phishing campaigns.
Spear-phishing: A sophisticated attack in which a particular entity, especially with authorization to high-level administration (such as a COO or CFO) is targeted.
Two standard phishing practices that malicious actors deployed during the pandemic are discussed below:
Using a phishing site: Attackers usually clone an original website by copy-pasting the HTML code from the source and deploy it on another URL but with striking similarities to trick the user into thinking it's genuine.
Developing similar URLs: Even though malicious actors can clone the websites entirely, it's impossible to implement the clone on the same URL as that of the original website. By making minor URL changes, cybercriminals add various authentication digital signatures and HTTPS certificates to make it more genuine.
What are the steps businesses can take to safeguard their virtual working Environments?
While the pandemic witnessed a rise in the number of phishing attacks, the good news is that businesses can take a few steps to secure their systems against such attacks. These are discussed below:
Businesses must consider the benefits of moving to the cloud and adopting SaaS, IaaS and PaaS according to the business needs, ditching the traditional on-premise way of handling their software needs
They must carry out regular employee training programs to make them aware of the risks
They must configure the virtual private network (VPN) properly
Businesses must introduce security elements for teleconferencing
There must always be a ready-made plan to identify and mitigate supply chain and third-party risks
The sudden switch to the work from the home environment has left businesses scrambling to find cost-effective solutions to ensure business continuity. They ignored the most crucial aspect – IT systems' security. However, there was a silver lining in the rising number of phishing attempts during the pandemic. Enterprises have started taking cybersecurity more seriously and taking proactive measures to improve their cybersecurity posture and keep malicious actors at bay.
Brad Slavin
CEO of DuoCircle LLC
https://www.duocircle.com
Brad Slavin is a security industry veteran and the General Manager at DuoCircle LLC, a cloud email security firm. Before joining DuoCircle, Brad began his career in network security by founding a regional ISP in California and was the co-founder of wireless wardriving and security software Netstumber.com, which was the recipient of the "Editor's Choice" – Laptop Magazine & Ziff-Davis i3 Award for innovation.
Duo Security
The Trouble With Phishing
5 Phishing Threats Catching Your Employees
Proofpoint
Beyond the Phish
5 Phishing Predictions


WELCOME to Issue #102 of the Bootleggers Buzz!
My, my, Bootleggers is getting festive this week with the holly, mistletoe, presents and Christmas pictures! With only a couple of weeks until Christmas and many other festive Holidays, players just cannot wait to get in the holiday spirit! But through the midst of Holiday giveaways, pictures and much more, someone will always put aside the Holiday Cheer to spray a few bullets across the game and into the accounts of many.
All the Happy Holidays and Merry Christmas cards must have gotten Sweetie and Andy into a Christmas mood as they decided to start an MS Paint Contest with Christmas as subject. If you want to have some fun with Paint and want to try and win Bootleggers dollars then check out Andy's article and join the Paint fun right away!
Apart from the contest, we had other events this week. As we lost two Nation Dons, the Buzz hooked up and sat down with the third one before he'd get killed as well. Between players scamming others by selling a crew spot that wasn't even theirs, crews versus crews and a new nation don, the game was pretty eventful this week, would you agree?
As always, we have our weekly segments such as "Behind the Name", "A Year Back" and our "Buzz Tutorial". As promised, "Crew of the Week" is back with a look at Strictly Business. The Buzz is also proud to launch the "Bootleggers Holiday Tree" again this year, so start decorating your Holiday ornament!
We are looking for writers. If you are interested in becoming a writer then read the re-printed version of "So You Think You Can Write?" in issue 97. Please submit a sample article of a recent Bootleggers event via selecting Application in the "Send a" located on the bottom of each Buzz. Remember to mind your grammar, punctuation and spelling. If you are dead by the time we contact you, please submit the same article all over again! Your articles will be reviewed as quickly as possible but please have patience, we won't forget about you.
Remember, anyone can write a freelance article and they are obviously free to do so. They are a chance for each of you to have a voice about the game and possibly share any thoughts that you may have with the BL community. We are sad that we haven't received many lately and would like to encourage everyone to send them in. This week, we are proud to publish three of them but we would love to publish more. So start sending them in!
Have a blessed week and enjoy the game!
The warm welcome received by The Grudge to the stats was only short lived as they were soon "new-schooled" their way off by none other than the notorious Resistance.
Learn everything there is to know about the Bootleggers Bootcast!
To celebrate Christmas myself and Sweetie are going to be giving away 1000 points to the best 'Bootleggers Christmas' themed MS Paint picture.
A look at the game, this time last year.
Over the course of this reset, we have been graced with the present of 25 promotions from State to Nation Don, and with each passing promotion, the thrill and anticipation to see what the new Nation Don will do next never gets old!
Let's come together to make the best Holiday Tree the internet has EVER seen!
Strictly Business is this week's crew of the week!


text:
Board of Trustees Discuss 'Ongoing Litigation' in Closed Call
September 22, 2011 12:00 am by Jorge Rodriguez-Jimenez
Florida A&M's Board of Trustees held a closed, call-in meeting on Sept. 19 to discuss ongoing litigation.
Article 286.011 Chapter 8 of the Florida Statutes and Articles 5.11 and 5.12 of the Board of Trustees operating procedures grants FAMU's Board of Trustees the right to hold closed meetings to strategize with an attorney about pending litigation before a federal court.
The attorney-client portion of the meeting can only be used to discuss settlement negotiations, and a strategy session related to litigation expenditures. Avery McKnight, counsel for the board, said the board is not allowed to make any final decisions or take actions during the attorney-client session.
"Final decisions must be voted on in the Sunshine," McKnight said.
The meeting began at 2:25 p.m. after a roll call of the trustees. Seven members were in attendance, Solomon Badger, chair, Karl White, Torey Alston, William Jennings, Rufus Montgomery, Marjorie Turnbull and Faculty Senate President Narayan Persaud.
After a briefing by the attorney, the BOT entered into the attorney-client portion of the meeting. After concluding the attorney-client session the BOT made a final vote. Trustee Jennings motioned that the BOT authorize the legal team to enter into negotiations consistent with the attorney-client session. The motion was seconded by White and then the board unanimously agreed to proceed with the motion.
University officials still cannot make comments on the ongoing litigation.
"In light of Florida Statutory 1012.91, paragraph two, the university is unable to provide any comment," said Pamela Tolson, director of media relations, responded by email.
The attorney-client session was recorded by a certified court reporter who was in Lee Hall. The transcript will become a part of public record after being filed with the university clerk.
"No part of the session can be off the record," said McKnight.


text:
import { createStore, applyMiddleware, compose } from 'redux';
import thunkMiddleware from 'redux-thunk';
import createLogger from 'redux-logger';
import rootReducer from '../reducers';

export default function configureStore(preloadedState) {
  const store = createStore(
      rootReducer,
      preloadedState,
      compose(
          applyMiddleware(thunkMiddleware, createLogger()),
          /* eslint-disable no-undef */
          window.devToolsExtension ? window.devToolsExtension() : f => f,
          /* eslint-enable no-undef */
      ),
  );
  if (module.hot) {
    // Enable Webpack hot module replacement for reducers
    module.hot.accept('../reducers', () => {
      const nextReducer = require('../reducers').default; // eslint-disable-line global-require
      store.replaceReducer(nextReducer);
    });
  }
  return store;
}

redpajama_set_name: RedPajamaGithub


June 6, 2018 • Of Americans who shop online, 92 percent have shopped on Amazon, according to a new NPR/Marist poll that shows the company creating new shopping habits and retaining a striking amount of trust.
December 5, 2017 • Sen. Chuck Schumer is urging retailers to stop "Grinch bots" that use sophisticated software to buy out the most popular toys of the season and sell them for a hefty markup on third-party sites.
November 22, 2017 • In reaction to a recent decision by UPS to add a peak holiday delivery surcharge, some retailers are adding rewards and discounts for customers who choose "no hurry" slower delivery options.
August 23, 2017 • The world's largest retailer will hawk its products on Google Express for the first time, in a play to get a bigger chunk of the growing voice-enabled shopping market currently dominated by Amazon.
March 4, 2017 • Amazon has opened its latest brick-and-mortar bookstore — the first on the East Coast. But an independent bookseller in the Boston suburb says: "I think that we're going to be OK."


text:
Karl Urban Wants Nothing To Do With Star Wars And An Original Story For Star Trek 3
Karl Urban has ventured in to deep space, where no man has gone before, but he is rather adamant that he has no interest in visiting a galaxy far, far away. In a recent interview, Urban explicitly states that he does not want to be in J.J. Abrams upcoming Star Wars: Episode VII, or any future chapters in the franchise.
Urban has a close relationship with Abrams, having appeared in both of the director's Star Trek films, but when IGN asked if he was he had tried to leverage that friendship into a part in Episode VII, he delivered an emphatic, "No, absolutely not."
That's a rather vehement answer, one without a lot of room for interpretation. Such a response could lead one to believe that the South African born actor has something against the franchise of Luke Skywalker, Han Solo, and Darth Vader. That, however, is far from the case. Asked if he is a fan, Urban replies:
Oh my God, yes…I grew up watching it. That was the Holy Grail for me. I was a fan of Star Trek growing up. Star Wars was it. Star Wars was like…I remember waiting for two/three years for that next installment, for Empire Strikes Back and Return of the Jedi. I've seen every single Star Wars film, even the animated, The Clone Wars, and all that sort of stuff. I just love that universe.
So that's good, we can still like Karl Urban, but there are definite reasons for his stance. Having already made a commitment to Star Trek, one that he fully intends to see through to the end, he wants to keep the two worlds separate. He says, "Being in Star Trek, to suddenly be in Star Wars wouldn't feel right to me."
Even though Abrams links the two properties, Urban differentiates between the behind-the-scenes and in front of the camera personalities.
I wouldn't want to do that do an audience. I, as an audience member, wouldn't want to see an actor from Star Trek in Star Wars. I just wouldn't. When I go into a Star Wars movie I want to be completely enveloped. I don't want to be taken out of the picture by going, 'Oh my God, there's Scotty, what's he doing in Star Wars?'
Though Urban was reticent to offer a guess as to who might helm Star Trek 3, he was confident that Paramount will have the film in theaters by 2016, which marks the 50th anniversary of the franchise. Talking about that film, he is looking forward to a story that is more wholly original than the last one. While Into Darkness tipped its cap to Trek history with the inclusion of Khan, Urban wants the next film to "Strive to be something different and new." He points out that Star Trek was supposed to be "about space exploration. And it would be really wonderful to harness the spirit of that and apply it to the next film, so that we do something different than a revenge-based picture." I think all of us would like to see that.
Urban is, obviously, no stranger to genre fare. In addition to Star Trek and Star Trek Into Darkness, he's appeared in the likes of Riddick, Lord of the Rings, and Dredd. This fall we'll see him in Abrams and J.H. Wyman's (Fringe) robot buddy-cop series Almost Human.
Mark Hamill Proves He Understands Star Trek Better Than Patrick Stewart
Why Star Trek: Enterprise Failed And How It Nearly Worked
See Robert Downey Jr. As Star Wars Villain Grand Admiral Thrawn
Han Solo Appearing In A Star Wars Series On Disney+?


PE Central has partnered with S&S Discount Sports to provide a full range of sports and PE products for your program.
Cognitive: The student will be able to recognize the different food groups of the MyPyramid, what they consist of, and the different healthful foods that belong in each group.
Students will also be able to relate to the recommended daily servings values and compare them to their daily intake of each food group.
This poster is one that shows what the MyPyramid pyramid looks like as well as the daily recommended serving sizes, and the appropriate proportions for each group. Along the bottom of the board are descriptions of each of the food groups as they appear on the food pyramid; grains, vegetables, fruits, dairy, meats and beans, and oils. From each description, depending on the group, there are examples of the different foods that belong in that group, that ascend toward the title; eventually forming a pyramid.
24.01.2016 at 20:58:37 Get you add flour and cook should come out clean. Too old for cheesecake.
24.01.2016 at 13:10:37 Eater, but I have cut down my meat consumption.
24.01.2016 at 20:11:29 For the health don't try to rush this process and.
24.01.2016 at 11:22:38 Grill for another 3 minutes more or until the that sage with one of the onions.


We are delighted to inform you that the applications for the 2018 NLNG Undergraduates scholarships are now open. Nigeria LNG Limited hereby invites suitably qualified candidates who wish to pursue Undergraduates programme in the United Kingdom in September 2018 to apply for the scholarship.
Who Can Apply for NLNG Undergraduate Scholarship?
Interested candidates and qualified candidates are to visit www.nigerialng.com to apply. Click on the "Our CSR" menu to select "Education" from the drop down menu, and then click on the scholarship link on the page to access the application portal.
The deadline for the 2018 NLNG Undergraduates Scholarship is May 18th, 2018.


Born May 7th1937 in Weston, West Virginia you lived the transitions from black and white to color television and polaroid to Kodak to digital photography. You purchased one of the first microwave ovens that came on the market as well as one of the first dishwashers and smoke detectors for your first home in Philo, Ohio. You gave me my first Commodore 64 computer, Sony Walkman, and you purchased me a video camera to help record memories after the birth of your first granddaughter in 2000. You also got mom a whole lot of kitchen gadgets that I'm pretty sure she still doesn't know what to do with. On the plus side at least you only had to eat fish sticks the first year of your marriage.
It is interesting the misconceptions that people have of only children; they often think that we grow up leading lonely lives. They would be wrong. When I wanted to learn to run track, you took me out behind the barns and taught me to run. You took me to the lake to learn to swim. Dang, life's rough when your dad was a former frogmen/navy seal. I decided to try out for basketball; you played basketball throughout your entire highschool career so you taught me to play. Sorry I didn't make the team; I hope you weren't too disappointed. I had more fun playing with you anyways. Oh yea, and we had that cool rope swing that you got the great idea to have swing over the huge embankment. That was a lot of fun; the whole two swings we got in until mom caught us, and made you take the swing down. I'm not entirely sure, but I think you got one of those talks that usually made you roll your eyes and grin at me.
I'll never forget the night you came home from work and told me that we were moving to Snortin' Ridge. I didn't want to move; I had a best friend and a cool bedroom and a teacher that I really liked (even if she was the reason I was and am a vegetarian). I also had a playhouse and cool neighbors. You asked me to come over to sit on your lap. I could never stay mad at you when I was sitting on your lap. I always felt so safe and snuggly in your arms. But you promised me a horse; my very own horse if I was okay with moving. Okay? Hand over the boxes, let's go. Best yet, a couple of months after we moved and were settled in, Gypsy came home and was the best horse ever. A year or so later, Moochie came home and was the best pony ever. I sure wish I would have realized to appreciate them more. I'd give anything to have a horse and that time with you back.
I guess what I didn't realize until now is that I was as much a daddy's girl as Ry was a grandpa's girl. I followed you around as much as she did and reaped the benefits and rewards as much as she. Of course, she like me also experienced the Butler "sense of humor." We have pictorial evidence of the infamous lemonade tree that you convinced her was the source of her beloved drink but she should count herself lucky at least she didn't go to high school and ask her science teacher about milking a pigeon like a certain unlucky daughter did. She also didn't come home from a date and have the porch light automatically turn on to find a scarecrow body swinging from the porch ceiling—I'm still convinced I got my first scare wrinkle that night. Then again at 16 she is convinced we have to leave Wisconsin and head back to Ohio to find really good cheese. And in elementary school she was convinced she needed a plan just in case a band of wild high schoolers broke into our house—according to you and her, she was going to hide in the bear cave with her shot gun and some cheese until it was safe to come out. Of course she would be wearing her boots just like grandpa—I think you got her her first pair well before she could walk but I think I also had my first pair before I could walk from your dad. Then again my dates were treated to being met at the door by Bandit, the rescued racoon, and having to feed her chicken, oreo cookies, and marshmellows if they wanted to get back into their cars. I suppose that that time Dan and I convinced Ryley we were going to leave her with the Medicine Man for a few months was kinda almost similar in an apple truly doesn't fall far kinda way.
Everyone knows the love story between you and your girls, but what I don't think most people realize is the connections you had with your boys. You and Caden had a rocky start. Caden didn't respond to the usual Jerry Butler tactics—Caden marches to a different beat---we call that drum beat autism now but we didn't know that at the time. For the longest time he was terrified of the back of your head if you had a hat on and the front of your head without a hat. But he could tolerate and even enjoy your company if you wore a newspaper, so that's what you did and in time you two worked out a pretty darn good relationship that didn't even include newspapers. He loved the stories about the weasels and eventually was even able to play along in the stories although he never quite knew if the weasel was real or not and honestly he didn't want to know truth. The magic of the stories was in the not knowing. His Butler skill is the ability to tell the same knock knock joke over and over a million times and ironically the millionth time he still finds it funny. He is usually the only one, sound familiar?
He also got your heart dad. Elf, his service dog, is your Tandy/Waggles/Squeaker/Teddy and every other dog you have ever loved. He is fiercely loyal to his dogs and his cats. He reminds me of the winter you were coming home from Western Freight and you heard the faint meowing. You searched and searched in the bitter cold before finding a tiny kitten stuck in a phone booth. You knew he wouldn't last long so you kicked in the frozen door and brought Henry home. Caden is destined to rescue the Henries of the world; I know you will be proud of him.
He told me that he isn't sad that you are gone because he knows you are really happy where you are cause you can breathe better but he sure wishes you had email. I agree with the sentiment but I'm much more selfish and miss you like crazy. Email would be nice though.
He has no fear just like you. Sayre talks about grandpa's house and his tractors all the time. You'll always be his John Deere Green grandpa and I'm pretty sure that's not a bad thing. I'm also pretty sure he'll never read directions nor think he needs to and I'll withhold judgement on that one because just like you, he'll never listen anyway.
I wish you could have met Emeri, but I promise she will know you dad. I'm going to make books for the kids and pillows out of your flannel shirts for them. Please don't roll your eyes at me like that—I'm going to use my sewing maching so you and grandma Butler should be pretty happy at the moment, assuming I don't sew myself into the shirts or anything ridiculous like that. Just promise me that you'll visit us dad and maybe help us in China because I'm nervous. Emeri has had a really hard life and you were always so great with kids; we could really use your loving touch to make her feel safe.


Founded in 2010, Mankato Brewery is proud to revive the brewing tradition in the Key City. Mankato Brewery will be the first production brewery in the community since 1967. Focused on creating authentic beers that reflect the heritage of the region and its people, the crew at Mankato Brewery invites you to try their beer and to Experience Local Flavor.


The Civil/Municipal Department at CBCL Limited provides efficient, cost-effective solutions for municipal engineering problems for a wide range of clients. These client groups include municipalities, provincial and federal government departments, private land developers, contractors, industrial parks, and a variety of commercial, institutional and industrial clients.
In addition, the multidiscipline resources of CBCL Limited are also available to provide specialized support to projects undertaken by the Municipal Department.
The Civil/Municipal Department employs senior professionals who are specialists in each of the group's areas of expertise. Intermediate and junior engineers, technicians, CAD operators and clerical staff support these key personnel. The Civil/Municipal Department makes extensive use of the latest computer hardware and software technology to enhance the efficiency and technical skills of its personnel. The scope of services offered by the department includes: municipal servicing studies and assessments, preliminary and detailed engineering design, project management, construction tender document preparation, construction tendering, construction contract administration, and on-site construction inspection.
CBCL's Municipal design team has in-depth experience in all aspects of municipal collection and pumping systems. With regard to gravity systems, we have conducted pre-design servicing studies (including wastewater characterization and flow gauging studies); inflow and infiltration studies; wastewater collection system condition assessments; pipe material selection analyses; as well as pre-design, detailed design and construction related activities. We have also provided similar services for pumping station projects and have conducted numerous pumping station inflow/outflow investigations and pump selection analyses.
In a multi-disciplinary team approach, the Civil/Municipal Department provides site servicing support services for various building projects managed by other CBCL departments. These services provide for water, sanitary sewer and storm sewer servicing to individual commercial, institutional and industrial buildings. The Civil/Municipal Department also provides design services for site grading, roadway access to building sites and parking lot design services. These services have typically been provided for conventional engineering projects, but we have also recently provided these services on a variety of design-build projects.
CBCL Limited provides construction contract administration and on-site inspection services for many of the municipal engineering projects undertaken by the firm. Our Field Services Group includes a senior construction manager and five construction inspection technicians. Services offered include full-time inspection, progress payment certificates, system testing and commissioning, project certification, record drawings, and operations and maintenance manuals.


Why does snoring exist? Shouldn't it have been selected against? I know my dog snores like anything, but does it exist in wild animals?
Nick - That's a fantastic question! One of the things that struck me about snoring is evolution. You said that why hasn't it been evolved out? Well, the shape of our faces has changed quite considerably since we've transitioned from being apes into hominids, and then to humans. That's aided speech, we've changed our diets, so I think all these changes may have predisposed us, to a degree, to snoring.
What is snoring? It's turbulent airflow through your upper airway. Lots of things can make that worse: obesity is a big problem. We know that weight gain tends to make snoring worse.
Nick - Why? Because you lay down fat, as well as peripherally, internally around the larynx and the upper airway, and that narrows the upper airway. Also, most of us when we go to sleep the muscles in our pharynx relax so the upper airway, the muscles relax. If you fat-load that, it will shrink in volume and, therefore, you'll get more turbulent flow through your upper airway. Also, it can predispose you to medical problems like sleep apnea where actually the throat shuts down during sleep because the muscles become too relaxed and that caused lower quality sleep and daytime sleepiness. Alcohol and various other things that people do make snoring a lot worse.
In terms of why hasn't it been weeded out in evolution? I was interested by that. One theory I thought about was if you snored do you keep people around you awake? Does that actually protect you in evolutionary terms? It's a controversial thought!
Chris - So you're saying it's been selected in? If your husband's snoring and you're therefore kept awake all night then you can wake him up if any danger appears. That's a brilliant suggestion.
Nick - It might be a selection pressure - I don't know.
Dan - I was interested on that because I think part of the question was to do with animals and my dogs both snore. They're terrible at it. But I was just wondering, now you've brought that up about this selection it's made me almost rethink because in the animal kingdom you would almost have thought it was counterintuitive the fact that you've got an animal that's snoring. But I'm just wondering if it's the pack animals that snore, and if we take the solitary animals. If the solitary animals don't snore because I like that idea that there's somebody in the pack that's more alert.
Nick - Well, I've been to zoos and I've seen many animals snore. With dogs I don't know if, because they've been bred over time for certain characteristics, and we know certain bad characteristics have been bred into dogs in terms of the shape of their snouts, so we might be responsible, in part, for making dogs snore by the way we've selected them.
Chris - What about doing something about it? You've mentioned some of the points so you could reduce your alcohol consumption. Weight loss: presumably if you move some of the fat from around the internal tissues. I didn't realise we accumulated fat in the way you're saying inside and narrowed the airway but that should help to. But is there anything else, if someone's a really bad snorer, that they could do about it?
Chris - You don't have a lot of choice if you're asleep though. You don't really dictate what position you're in can you?
Nick - You can do. There's various strategies you can adopt.
Chris - The whole stitching cotton reels and fir cones into the back of your pyjamas - that idea? Is that what you're getting at?
Chris - Tennis balls in there or something?
Nick - Well, it's a rubber dog ball. It's quite spiky and that keeps her of her back so that's quite inventive when she told me about that. I've suggest that to a few gentlemen, but they've blanched at that thought.
Chris - I'm not surprised!
Nick - Indeed! There are biofeedback devices you can can buy that vibrate when you start snoring loudly and get you to roll off or change position to help with that. If you want to try something a bit more invasive there are devices called Mandibular Advancement Devices. They're devices that go in the mouth, fit the teeth top and bottom and pull the bottom jaw forward. So they are a way of reducing snoring volume and also we use them to treat mild to moderate sleep apnea. But sometimes it's just a fact of life.
Chris - I should just start with the simple stuff and build up from there then?
Previous What is mindfulness and does it work?
Next How much stress is too much?
How does NASA select astronauts?


text:
Look Inside (2.4M)
Best Tall Buildings 2012
CTBUH International Award Winning Projects
The Council on Tall Buildings and Urban Habitat (CTBUH) is the world's foremost authority on tall buildings. This book is the culmination of the annual awards process in which the CTBUH recognizes outstanding tall buildings from the past year. One winner is chosen from each of four geographical regions (Americas, Asia & Australasia, Europe, and Middle East & Africa) and a further award presents the title of overall Best Tall Building "Worldwide" to one of the four regional winners. This year the Council also added a new award, the CTBUH Innovation Award, recognizing a specific area of recent innovation in a tall building project. Additionally the CTBUH awards two annual Lifetime Achievement awards to individuals who have made a significant contribution to the design or technical advancement of tall buildings.
The book provides an overview of the winning, finalist and nominee projects (and careers of the Lifetime Achievement winners). Winning and finalist projects are fully profiled with stunning images, as well as detailed drawings and plans, which accompany an in-depth account of the buildings' architectural design, structural design, and any innovations in fields such as program or sustainability. The book also features the official current list of the "100 Tallest Buildings in the World" as the CTBUH is the internationally recognized official arbiter of tall building height.
Highlighting the best tall buildings from 2012, Best Tall Buildings seeks to represent those projects with innovative design and which strive to advance the profile of the tall building as an integrated sustainable element in cities across the world. Fascinating and inspiring reading for all those interested in the planning, design, and construction of tall buildings.
Publisher: CTBUH in conjunction with IIT and Routledge / Taylor and Francis Group, Chicago, 2012
ISBN13: 978-0-415-64002-2 ISSN: 1948-1012
Hard cover with jacket, 224 pages, 8.25"W x 10.25"H


Demetrious Johnson submitted Chris Cariaso in the second round of their main event title tilt at UFC 178 on Saturday night, further enforcing his incomparable defence as he continues to clean through the division.
It was on a sublime night inside the eight-sided UFC cage that also featured Conor McGregor prevailing in a highly-anticipated grudge match with Dustin Poirier. Dominick Cruz made an emphatic return lower down the card and Eddie Alvarez was beaten in his UFC debut.
Is there no stopping Demetrious Johnson?
With now five straight title defences to assert himself as the validated kingpin of UFC's flyweight division, his win over Chris Cariaso was a formality. Once again, he showed his big leap in skills improvements with a kimura to win the bout.
For the first round, "Mighty Mouse" dictated the pace inside the Octagon with some swift striking. Going to the ground, his perfect performance would last for around seven minutes or so, with a kimura that left his opponent no option to tap.
"I was a little too patient for my own good", explained Johnson post-fight. Even with a fantastic performance like that he can still find improvement. That's a Champion for you.
Arguably the greatest MMA fighter on the planet to not fight in the UFC, Eddie Alvarez finally ended that statement when he stepped into the Octagon to face Donald Cerrone.
Starting off with a solid round where his aggression peaked in the clinch, his heavy hands got working on "Cowboy" Cerrone although he didn't come close to the finish. Takedowns were stubbed and Cerrone may have stumbled out of the blocks, but he did eventually get into full swing.
Alvarez was hurt in the second bracket, before Cerrone would unleash heaps of brutality upon the established Champion, bruising the legs and eventually forcing him off his feet to grind it out in the third.
What was on everyone's lips both before and after the curtain had been drawn over UFC 178 was Conor McGregor and Dustin Poirier.
A highly-anticipated grudge match between the two featherweights continued to swivel out into chaos and animosity, with security having to refrain the pair in the face-offs. Even when Poirier entered the Octagon, he had a visual altercation with the Irishman forcing security to step in. They were ready to go.
Hands down, moving like fluid, McGregor took some shots and gave some, but when Poirier really opened himself up for a true exchange with the "Notorious" one, he was clipped round the ear and crumbled to the ground allowing McGregor to finish it off and the referee put a stop to the fight.
The American did indeed claim that he was struck behind the ear however he was already stunned. It's looking like McGregor is the 'real deal', and the Irish fans - occupying 10% of ticket sales for the event - absolutely know it.
"I don't just knock people out, I pick the round".
He's coming for the World title.
Tim Kennedy had Yoel Romero stunned. On the stroke of the end of the second round. However, the "Solider of God" wasted time and sat on his stool for an extra and pivotal 29 seconds that allowed him to recover.
Livid, Kennedy approached Romero and told him to get up. He eventually did and then shocked him in the third round.
Catching him with a brutal right, Romero had it won, battering him and leaving him bloodied for the fight to stop.
There were ignited protests after the fight though as Kennedy claimed that Romero should have lost because he couldn't get up in the time required. Kennedy was hard-done-by.
It's been a hard journey in Cat Zingano's absence from UFC, but when she did return following an injury and tough personal issues, she stated herself as a true contender for the UFC Women's Bantamweight championship.
Still undefeated, she rallied past an early onslaught from Amanda Nunes before finishing off the fight in the third round.
The last time Dominick Cruz fought in the Octagon was 3 years ago where he defeated Demetrious Johnson.
Following two hard knee injuries and a groin tear, he finally returned and put setbacks away to absolutely destroy Takeya Mizugaki.
There were no signs of deterioration either, with slick footwork and an awkward style for Mizugaki to deal with, eventually going out after just a minute or so of action.
Simply an outstanding night inside the Octagon.
Demetrious Johnson continues to dominate the Flyweight division with a win over Cariaso and McGregor rattles Poirier at UFC 178.


Gorgeous handmade basket, great for fruit bread or nick nacks. Hand crafted from unbleached cotton rope and stitched with Aubergine cotton. Other colours can be available, please send us a message for bespoke orders. Wipe clean only.


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The Beach Boys Return To The Van Wezel in February
The performance is on Tuesday, February 21, 2023 at 7:30 p.m.
The Van Wezel Performing Arts Hall will welcome The Beach Boys to Sarasota on Tuesday, February 21, 2023 at 7:30 p.m. Tickets on sale Friday at 10 a.m.
As The Beach Boys mark more than a half century of making music, the group continues to ride the crest of a wave unequalled in America's musical history. The Beach Boys - who have become synonymous with the California lifestyle and an American icon, are bringing their shows to fans around the world.
Since the band's co-founder, lead-singer and chief lyricist Mike Love penned the lyrics to The Beach Boys' first hit, "Surfin'" (1961), dozens of the bands chart toppers have become eternal anthems of American youth: "Surfin' USA," "Surfer Girl," "Fun, Fun, Fun," "I Get Around," "California Girls," "Help Me Rhonda," "Barbara Ann," "Good Vibrations," "Wouldn't It Be Nice," "Rock and Roll Music" and "Kokomo."
The Beach Boys have sold over 100 million records worldwide and have received more than 33 RIAA Platinum and Gold record awards. The Rock And Roll Hall of Famers where also honored at the 2001 Grammy Awards with the Lifetime Achievement Award. With more than five decades of touring under their belts, The Beach Boys have performed more concerts than any major rock band in history.
The Beach Boys recently debuted Sail On Sailor - 1972, a new expansive multi-disc and digital box set via Capitol Records/Ume. Produced by Mark Linett and Alan Boyd - the team behind 2013's GRAMMY Award-winning SMiLE Sessions and last year's acclaimed Feel Flows - The Sunflower and Surf's Up Sessions 1969-1971 - the box set documents and dives deep into their transformative and fruitful 1972 era. The comprehensive 6CD Super Deluxe Edition features newly remastered versions of Carl and the Passions - "So Tough" and Holland, plus Holland's Mount Vernon and Fairway (A Fairytale) EP (complete with its original instructions to "please listen in the dark"), and boasts an unreleased live concert recorded at NYC's famed Carnegie Hall on Thanksgiving, 1972, the first-ever release of a complete Beach Boys concert from this era with the original setlist. The set also includes a bounty of unreleased outtakes, live recordings, radio promos, alternate versions, alternate mixes, isolated backing tracks and a cappella versions, culled from the historic album sessions. In all, it contains 105 tracks, 80 of which are previously unreleased.
The Beach Boys are led by Mike Love, who, along with longtime member Bruce Johnston, musical director Scott Totten, Brian Eichenberger, Christian Love, Tim Bonhomme, John Cowsill, Keith Hubacher and Randy Leago continue the legacy of the iconic band. This concert will not feature Brian Wilson, Al Jardine or David Marks.
Tickets are $37-$95 and can be purchased at www.VanWezel.org, by calling the box office at 941-263-6799 or by visiting the box office Monday through Friday between 10 a.m. and 6 p.m. and Saturday from 10 a.m. to 4 p.m. Groups of 10 or more should contact 941-263-6726. Pre-show dining is available through Mattison's at the Van Wezel which is located inside the theatre. Reservations can be made on VanWezel.org or through the box office.
Related Stories View More Sarasota Stories
Pat Benatar and Neil Giraldo Come to The Van Wezel in April
Multi-platinum, chart-topping GRAMMY Award winning duo Pat Benatar & Neil Giraldo have announced more dates to their 2023 North American headlining tour. The tour stops at the Van Wezel Performing Arts Hall on Monday, April 24, 2023 at 7:30 p.m.
TOM JONES: AGES & STAGES Tour Comes To The Van Wezel
The Van Wezel Performing Arts Hall will welcome TOM JONES to Sarasota! Tom Jones: Ages & Stages Tour will take place on Saturday, May 13, 2023 at 8 p.m.
Westcoast Black Theatre Troupe Continues 2022-2023 Theatre Season With DREAMGIRLS
Westcoast Black Theatre Troupe will continue its 2022-2023 "American Dreams" theatre season with the highly-anticipated production, "Dreamgirls." The show runs from February 22 through April 9, 2023.
Art Center Sarasota Welcomes Javi Suárez As Board Member
Philip C. Baker, whose position as chairman of Art Center Sarasota's board of directors commenced with the start of the fiscal year, recently announced that the organization has welcomed the celebrated architect and artist Javi Suárez to its board of directors.
Hermitage Announces Benefit Concert With Andy Sandberg And Broadway Guest Stars In March
The Hermitage Artist Retreat (Sarasota County, Florida) has announced a one-night-only benefit concert to celebrate the 20th Anniversary Season of the Hermitage and to raise funds for ongoing repairs to the Hermitage following the impact of Hurricane Ian earlier this season.
Florida Studio Theatre Presents The Regional Premiere Of Fast-Paced Drama, THE LAST MATCH
Sarasota SHOWS
Big Sexy: The Fats Waller Revue
Westcoast Black Theatre Troupe (4/19-5/28)
FST Improv Presents: When X Meets Y
Florida Studio Theatre (2/11-2/11)
An Evening with Norm Lewis at VPAC
Venice Performing Arts Center (2/26-2/26)
Manatee Performing Arts Center (4/05-4/23)
FST Improv Presents: Life's a Beach
A Place in the Sun: A Tribute to Stevie Wonder
Florida Studio Theatre (11/16-3/26)
Flyin' West
What the Constitution Means to Me
Backwards Forwards Back
Urbanite Theatre (3/24-4/30)
The Lion, The Witch, and the Wardrobe
The '70s: More Than A Decade
The Players Centre (3/09-3/19)
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Best in Show: Project Runway Winner Gretchen Jones
Pitting judge against judge and infuriating Tim Gunn, her win was the most controversial in the show's history. Love her or loathe her, she's a force of fashion to be reckoned with.
By Katie Connor
Let's get one thing straight: Gretchen Jones knows what you're thinking. "I'm the bitch!" she laughs. It's a perception she's ready to disprove—and have a little fun with. "I got an evil purple lipstick," she notes of a rare stray from her signature reddish-orange lipcolor (So Chaud by MAC). "And I've started wearing heels. I'm 5'11" and already considered a bitch—I may as well take it up a notch!"
The 28-year-old's ability to laugh at herself seems out of step with the serious, all-knowing competitor seen on Project Runway's eighth season. "All of my sarcasm got stripped away on the show," she says. Still, the striking designer from Portland, Oregon, takes responsibility for what did make it on air. "I have a strong voice, and I communicate my tastes in a manner that you either like or don't," she admits. "But there's a difference between critique and taste. My tastes aren't for everybody—that's what fashion is." Fair enough. Yet for many, such rationale does nothing to lessen the sting of Jones' triumph over crowd favorite Mondo Guerra. Both designers presented strong finale collections—strong enough to split the judges straight down the middle. While Nina Garcia and Michael Kors championed Jones, Heidi Klum and guest judge Jessica Simpson stood firmly for Team Mondo. "A lot of people were really upset that he didn't win," Jones says of her runner-up. "I'm OK with that. Mondo is a genius and very compelling, but I think my work spoke for itself." Indeed, "Running Through Thunder," Jones' winning collection, speaks to a new tribe of women—one whose casual-cool exterior belies all-powerful ambition. Who but Jones herself is better to model the Southwestern-inspired chevron prints and one-of-a-kind jewelry? "There's a difference between the Lady of the Canyon from the '70s and bohemian women now," she says. "I consider myself a modern bohemian woman, but I still wear 5-inch heels and tailored trousers. I have big goals." Among them, an entire lifestyle brand that bears her name. But first, she'll put the prize money toward paying off her debt. Next she hopes for an apprenticeship under one of the greats: Diane von Furstenberg, Donna Karan, or—fingers crossed—Michael Kors. "I'm the 'ask for what you want and you will get it' type of girl," Jones says. Based on her track record, she's got a lot coming her way.
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Two Tamale university students sentenced to death by hanging
By Maame Aba Afful
Category: general news
Two University students sentenced to death by hanging
The Tamale High Court has sentenced two students of the Tamale Technical University(TaTU) in the Northern region for robbing and murdering the Head Pastor of the End Time Believers Bible Fellowship in Tamale last year.
The Court, presided over by Justice Edward Apenkwah, sentenced the two students, Kwame Dogyi and Obio Akwasi, who are cousins, after the jury had returned a unanimous verdict of guilty of conspiracy to commit a crime, to wit murder.
The Tamale District Court One, presided over by Mr. Anthony Asaah, on Wednesday, April 11, 2018, committed Dogyi, 28, and Obio, 21, to stand trial for the murder of Pastor Ocran.
During the trial, the prosecution called nine witnesses, while the convicts called no witnesses, and at the end of it, all the jury returned a verdict of guilty of conspiracy to commit crime.
The facts of the case, as presented in court by the prosecutor, Mr. Salia Abdul Quddus, a Principal State Attorney, were that about 11 a.m. on November 9, 2017, the two attacked Pastor Ocran at Kumbuyili.
University students arrested over death of Pastor
They stabbed him with a knife in the chest and later hit him with a pestle in the head, killing him instantly, and locked the body in a room.
The prosecution said the two cousins, after the act, took away a Samsung Galaxy phone, GHS200 and a Toyota Highlander 4X4 vehicle, with registration number GN 1736-14, all belonging to the deceased.
About 10 p.m. on the same day Ben Asamoah, an assistant pastor of the church, informed the police that he had visited the head pastor and found him dead in his house, while his Toyota Highlander was missing.
About 3 p.m. on November 10, 2017, the police in the Northern Region had information that the vehicle had been sent to the Tamale Industrial Area for re-spraying and thereafter offered for sale for GHS10,000.
The police feigned interest in buying the car, and thorough investigations, Dogyi, a third-year Engineering student of TaTU, was arrested. He mentioned his cousin, Obio also a third-year student of the same university, as his accomplice.
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G3 Development
West Jordan, UT LifeVantage 'Chief BioHacking Officer' (Pro-4 Distributor) Adam Green Discloses Reason #6 to Open Search for Top Direct Sales Earners in Scandinavia
West Jordan, UT -- (SBWIRE) -- 09/07/2018 -- "You yourself, as much as anybody in the entire universe, deserve your love and affection" – Buddha
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PhysIQ helps burn stubborn fat, increase energy, and support your digestive and immune system with a scientific, clinically proven formulation designed to trim the fat and boost the way one feels. They use BIO-tract® to improve delivery of healthy bacteria and proven fat burners like Sinetrol® and Svetol® to help meet weight management goals. PhysIQ is a complete system that features these benefits:
PhysIQ™ Cleanse - Helps remove toxins from the body, PhysIQ™ ProBio - Improves gut integrity, PhysIQ™ Fat Burn -To kick the body's natural fat-burning capabilities into gear, PhysIQ™ Protein Shake - To help curb appetite and build lean muscle, Together, with a healthy diet and exercise, they work as a comprehensive system to help slim down, feel better, and stay that way. http://www.lifevantage.com/wp-content/uploads/2015/12/US-PhysIQ-Product-Info-Sheet-WHOLE-LINE-V.01.pdf
"What lies behind us and what lies before us are tiny matters compared to what lies within us." – Ralph Waldo Emerson
NRF2: Reclaim Youth with Protandim: With Protandim Nrf2 Synergizer, one can take on aging with the only supplement that helpsthe cells produce their own antioxidants. Feel younger. Live healthier. That's the power of Protandim Nrf2 Synergizer. As humans age, the cells can't produce enough antioxidants to fight oxidative stress. And antioxidant supplements and "superfruit" juices just don't work - even if one likes spending a lot of extra money.
http://www.lifevantage.com/wp-content/uploads/2013/06/16032501.03_Protandim-Nrf2-FAQs.pdf
"No one can make you feel inferior without your consent." – Eleanor Roosevelt
Protandim Nrf2 Synergizer helps cells produce their own antioxidants, so one can neutralize free radicals, feel younger, and live healthier. By helping them repair and rejuvenate themselves, Protandim Nrf2 Synergizer works with the cells—the building blocks of life—to build an impressive résumé of health benefits.
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Reducing oxidative stress by 40% in just 30 days, Significantly reducing cellular stress through Nrf2 activation, Producing enzymes capable of neutralizing more than 1,000,000 free radicals, Helping to regulate survival genes, Helping the body repair and rejuvenate its own cells, Helping the body detoxify genes, keeping the master blueprint of the cell's function intact. http://www.lifevantage.com/wp-content/uploads/2017/06/US-Protandim-Product-Sheet-V.01.pdf
http://www.lifevantage.com/wp-content/uploads/2017/06/US-Protandim-Product-Sheet-V.01.pdf
(These statements have not been evaluated by the Food and Drug Administration; These products are not intended to diagnose, treat, cure or prevent disease; Compared to the free radical scavenging capacity of 2g of Vitamin C).
LifeVantage Science: LifeVantage is not a future breakthrough — they have proof it is happening now. They agree with leading researchers that extending human life is inevitable. However, they believe that in order to truly enjoy extreme longevity, they need to bio hack their health span.
LifeVantage specializes in a new science called Nutrigenomics; which is (1) Researching, (2) Testing, and (3) Creating products to address the biochemical effects of aging, with the ultimate goal of biohacking the human body to help people achieve optimal health as part of the normal aging process. In fact, we have 'Scientific Evidence' to show biohacking is possible. The National Institute of Aging (NIA) found that in male mice Protandim® Nrf2 Synergizer™ was the ONLY supplement Scientifically Proven to Increase lifespan by 7%. In plain English – we agree with leading researchers that extending human life is inevitable, but we also believe that in order to enjoy that increased lifespan, we need to lengthen our health-span. This science does not just help you FEEL GOOD, it lets you ENJOY LIFE—which also helps you feel good. http://g3development.lifevantage.com/biohackers/
LifeVantage is changing the view on aging. Looking for evidence? As scientists, so are they — and they've got mounds of it. When products work, the scientific community takes notice and comes to their own conclusions. Their products are tested in peer-reviewed published studies (23) from laboratories across the nation. Now they're using a groundbreaking new science called Nutrigenomics to help people bio-hack a healthier life. By studying the effects of nutrients and natural compounds on our genes, they're creating scientifically-backed products that support cognitive health and promote healthy aging on the cellular level.*
Their Nutrigenomic products support the body's natural cellular function by targeting the main biochemical effects of aging, issues like oxidative stress, natural mitochondrial deterioration and more. By awakening the body's ability to rejuvenate itself on a massive scale — whether by up-regulating your genes' ability to produce their own antioxidants, the cells 'ability to produce mitochondria, or the guts' ability to regulate bacteria — they're helping people stay on top of the aging process while delivering the mental clarity and overall well-being they need every day to get the absolute most out of life. http://g3development.lifevantage.com/products/
LifeVantage Vitality Stack! Organ Health: All can agree that the organs are kind of, um… a little bit, well... important. When it comes to better organ function, people need the right nutrients, like NRF1 Synergizer to boost mitochondrial function and help their organs work efficiently and NRF2 Synergizer to protect those same cells from oxidative stress. With Omega+, you support the cell membranes and receptors that improve the way the heart, blood, and genes function while giving the heart, eye, and brain the structural support they need. And ProBio supports healthy ratios of important bacteria, making sure the body extracts all the right nutrients. Human organs do a lot for the body—it's time to return the favor. http://g3development.lifevantage.com/products/vitality-stack/
Protandim® Nrf2 Synergizer™: What does Nrf2 Do? Protandim Nrf2 Synergizer is engineered to help people rejuvenate their cells. It's the only patented formula scientifically proven in a clinical study to reduce the oxidative stress in humans by an average of 40 percent in 30 days. It's been researched, tested and validated by some of the world's leading universities and institutions.
Protandim® Nrf1 Synergizer™: What does Nrf1 Do? Just because one is getting older doesn't mean they have to feel like it. Protandim® NRF1 Synergizer™ helps the cells produce more mitochondria, so they can feel younger and more energetic from the inside. It's a new breakthrough in nutrigenomics that helps bring back that youthful feeling to the body.
PhysIQ™ ProBio: What does PhysIQ ProBio Do? Long-term gut health and weight management go hand in hand. PhysIQ ProBio uses proven ingredients, BIO-tract® controlled release technology, and Wellmune® to give the digestive and immune systems the scientifically advanced support they need. It's a smarter way to feel better and keep health on tract.
WANT MORE INFO? http://www.lifevantage.com/wp-content/uploads/2018/03/US-ENG-Stacks-FAQ-V.01.pdf
OMEGA+: What does OMEGA+ Do? By combining DHA and EPA Omega-3 fatty acids, Omega-7 fatty acids, and Vitamin D3, Omega+ supports cognitive health, cardiovascular health, skin health, and the immune system. LifeVantage Omega+ fish oils are 100% traceable from boat to bottle, sourced from AlaskOmega®† Pollock and CodMarine®† Norwegian fish oil. http://www.lifevantage.com/wp-content/uploads/2018/03/17110902.05-US-EN-STACKS-Product-Info-Sheets-v06.pdf
About LifeVantage Corporation
LifeVantage Corporation is a pioneer in Nutrigenomics – a new science dedicated to biohacking the human aging code. Nutri-Genomics is the scientific study of the interaction of: (1) Nutrition and (2) Genes; especially with the prevention or treatment of diseases. http://investor.lifevantage.com/
LifeVantage engages in the identification, research, development and distribution of advanced nutraceutical dietary supplements and skin care products, including Protandim®, their line of scientifically-validated dietary supplements, TrueScience®, their line of Nrf2 infused skin care products, Petandim™ for Dogs, their companion pet supplement formulated to combat oxidative stress in dogs, Axio®, their Smart Energy Drink mixes, PhysIQ™, their Smart Weight Management System and Omega+, their 3-in-1 fish oil supplement.
https://g3development.lifevantage.com/products/protandim-nrf2/
LifeVantage was founded in 2003 and is headquartered in Salt Lake City, Utah. In 2009, LifeVantage switched their business model from retail to direct to consumers with Network Marketing. Network Marketing is the selling of goods where the distributor makes commissions. Bio-Hacking is the process of making changes to ones lifestyle … in order to 'hack' the body's biology and feel its very best. A 'Hack' is a 'quick solution' that solves a problem. https://vimeo.com/241179298
NRF2: Is a powerful protein that is latent within each cell in the body. It is unable to operate until it is released by an Nrf2 activator. Once released, it migrates into the cell nucleus and bonds to the DNA master regulator of the body's total antioxidant system. -Five Ingredients Activate Pathways: Ashwagandha, Bacopa, Green Tea, Milk Thistle, Tumeric. *
NRF1: Stimulates the production of proteins that are needed for cellular energy production and proteins involved in the making of new, healthy mitochondria. -Five Ingredients Activate Pathways: Acetyl-L-Carnitine, Quercetin, Grape Extract, Alpha-Lipoic Acid, Coenzyme Q10.*
TO JOIN TODAY http://g3development.lifevantage.com/products/?welcome=2
*These products are not intended to diagnose, treat, cure or prevent disease.
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Posted Friday, September 07, 2018 at 9:00 AM CDT - Permalink