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4 matches for Laird And His Lady Mr Kinairdht in the British Newspaper Archive
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Kendal Mercury Westmorland, England
tire of playing 4hshsroiqe. A «eod English riding, not snoogh for hsr. shoo? Room, 100 generally, in mob's attire—a breteh
appearance, which he evidently thought it his first duty to cultivate. _ His loose fitting coat was of iireproachable out; his waistcoat, no ( reach-me-down,' bat fitting without creases, and of spotless purity; his gloves ('twas miracle l.ow he got into
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Police Court, Edinburgh.—A case very extraordinary and distressing nature occurred Friday last. A tew days before, a gentleman residing in
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To the NEW CHAMPIONS...
To the NEW CHAMPIONS... Apr 2, 2017 21:47:00 GMT -5 Tampa Bay Bull Sharks, zephyr, and 3 more like this
Post by Miege22 on Apr 2, 2017 21:47:00 GMT -5
A very hearty CONGRATULATIONS!!!!
After losing a heartbreaking finals last season to the Tampa Bay Bull Sharks, the Houston Rockets came into this season with one mission: finish the job. Unlike a lot of teams that make it to the finish line and fall, the Rockets didn't make any big moves. They re-signed Kawhi Leonard and Rondae Hollis-Jefferson. They signed Paul Zipser and Norm Powell. But that was it. The Rockets were going to trust their core to improve, and improve they did. Kawhi Leonard took another step forward, firmly cementing himself as an MVP candidate. Nikola Jokic went to part-time difference maker to full-time game changer. All the while, Steph Curry continued to do Steph Curry things.
The season was not without adversity, however. The Rockets started the year without do-everything forward Khris Middleton, and there was no timetable for his return. The Rockets opened the season with a finals rematch against the Bull Sharks, but lost a hard-fought 5-4 battle. They righted the ship for 8 straight wins, setting up a showdown with a new power in the West: the Memphis Grizzlies. The Rockets fell, 7-2, but the match was far closer than the score showed. The Rockets rebounded to win their final 6 games, but disaster struck in the final week. Jabari Parker tore his ACL for the second time in his career and would be declared out for the playoffs.
The Parker now out, and Middleton just starting to find his footing, the Rockets seemed ripe for an upset loss. Their new big three was having none of that, though, as they combined for 491 points, 196 rebounds, 124 assists, and 46 steals. The Rockets snuck past Golden State setting up a Western Conference finals showdown with... the underdog Utah Jazz.
The Jazz have been one of the best teams in the league, arguably the premier franchise in the entire Western Conference. And yet, this was their first appearance in the Western Conference finals since 2014, when they made the finals and fell to Brooklyn. As the first weak came to a close, it looked as though the Jazz could pull off another upset. However, the Rockets kept on firing, eventually pulling away for an 8-1 win. Once in the finals the Rockets prepped themselves for yet another rematch.... for the second consecutive round, though, it wasn't to be.
The Washington Wizards took down the two-time defending champion Bull Sharks, guaranteeing that there would be a first-time champion this season. However, the Rockets were still looking to give the Western Conference their first NBA title since 2011. While the win wasn't secured until the last few days, the Rockets led throughout, proving that they were, by most every measure, the strongest team in the league this season.
The Rockets now enter rarefied air. They are one of only 6 teams to win a title. Every player on their roster is under contract through next season. They could be the strongest defending champion in league history, which is a strong statement given the recent champions we've seen. Now, the pressure is really on. The last two teams to win the championship have managed to repeat (Brooklyn 13-14, Tampa Bay 15-16). The Rockets will have a minefield to navigate in the suddenly powerful Western Conference, but they'll have the talent and experience to do so. We'll see if luck and timing will be on their side...
moltreszwarriors
To the NEW CHAMPIONS... Apr 2, 2017 23:29:11 GMT -5 Tampa Bay Bull Sharks, razorbacks, and 3 more like this
Post by moltreszwarriors on Apr 2, 2017 23:29:11 GMT -5
Great season, everybody. I look forward to seeing what you all bring on next year.
To the NEW CHAMPIONS... Apr 3, 2017 17:27:29 GMT -5 via mobile
Post by Tampa Bay Bull Sharks on Apr 3, 2017 17:27:29 GMT -5
Congrats, Houston!!
To the NEW CHAMPIONS... Apr 3, 2017 22:44:58 GMT -5
Post by crossover on Apr 3, 2017 22:44:58 GMT -5
Congrats Houston, great season!!!
Kots (Colorado GM)
To the NEW CHAMPIONS... Apr 4, 2017 6:52:19 GMT -5 via mobile
Post by Kots (Colorado GM) on Apr 4, 2017 6:52:19 GMT -5
Congrats mate!!
shahrom93
Post by shahrom93 on Apr 4, 2017 13:51:56 GMT -5
Congrats Houston, fantastic job!!!

redpajama_set_name: RedPajamaCommonCrawl


text:
Валерия Владиславовна Фадеева (род. 13 августа 1993 года, Балаково) — российская волейболистка, связующая.

Биография
Валерия Владиславовна Фадеева родилась 13 августа 1993 года в Балаково. Отец – Владислав Фадеев, генеральный менеджер женской сборной России, в прошлом тренер команды «Балаковская АЭС». Мать – бывшая волейболистка Ольга Фадеева.

Волейболом начала заниматься в Балаково. С 2002 по 2010 год тренировалась в группе подготовки команды «Балаковская АЭС».

С 2012 по 2016 год выступала за клуб «Протон». С 2016 по 2017 год играла за команду «Липецк-Индезит». С ноября 2018 по февраль 2019 года вновь выступала за «Протон».

Окончила Саратовский государственный аграрный университет. Увлекается конным спортом.

Примечания

Ссылки
 Профиль на сайте ВФВ
 Профиль на сайте volleyservice.ru

Выпускники Саратовского государственного аграрного университета
Волейболисты России
Игроки ВК «Протон»
Игроки ВК «Липецк»

redpajama_set_name: RedPajamaWikipedia


Wing Walden remembers that she saw Charred for the first time one Thanksgiving Day. The leaves had dropped off from the tree branches. The fall season plants had long ago dispersed their seeds on the wind. The remaining tall stalks were still holding onto their brittle, frost bitten leaves which seem to be clinging defiantly on them.
Wing was not sure what had caused her to look out the sliding glass door at that very moment, but she did, somehow knowing that she is being compelled to do so. Magical thinking or was it that she was still mourning her loss. Grief has a way of playing tricks on your mind. In truth, it didn't really matter which reason is was or that maybe it had been a combination of the two.
Wing's eyes traveled along the yard's edge where the mowed grass met the woods. There he was! Finally, after all these years, she had been gifted with the sight of him.
Charred had been sent to Wing many times on the dreamscape, but this would be the first time that she had ever seen tangible evidence of his natural existence. Charred was searching too, as he is walking towards the house, he sensed that she was inside and needed to be comforted by his presence. Separating the brush with his head, Charred peeked through the forest of grass, and while doing so, he stepped forward placing one of his front paws onto the lawn. His eyes looked upwards seeking her, his Human Totem. Wing, with a room full of people behind her, didn't say a word about what she is witnessing.
A smile came across the great lynx' face when he saw Wing. He hovered just long enough to be satisfied that she had recognized him and she understood that he was watching over her. The great lynx lowered his head and stepped back into the cover of the woods. Wing turned around to rejoin her family celebrating Thanksgiving while knowing in that moment everything had changed. Little did Wing know that November evening would be the beginning of Wing Walden's clairvoyant journey into her ancient past.
Wing Walden and Beau Badger are twin-spirits, who have loved one another many times and over many lifespans. Yet each time when their spirits found one another, it would always have the same tragic ending. Some would call that Karma but "others" would call it the result of one experiencing a Bad Medicine Death.
Relationships are creation stories! People create, maintain, and sometimes unintentionally destroy the love that was meant for them without giving any thought to the long term consequences inflicted upon their own souls and psyche.
If one believes that you have only "one life" you may feel pressured to experience more and seek change often to fulfill the belief that one's physical death is the final stopping point of your journey.
Wing Walden believes that both humans and animals are spiritual beings. The connection between the different species is sometimes obliterated due to the practice of humans eating meat. Many people have forgotten the gift that animal beings provide and they are slaughtered and consumed without conscience or thanks. This is where modern mankind differs from the paleo and ancient peoples.
The ancients understood that an animal sacrificed its life to provide mankind with a future. The hunters who sought the animals often prayed for and over their prey; and as a right-of-passage young men and woman would seek the experience of a Vision Quest, the companionship of a Spirit Guide; and the teachings and lessons to be learned from Animal Totems.
Limberlost The Vision Quest of the Totem Seekers is the story of the "many hats" worn by human beings and Animal Totems. Who, by understanding their decisions and experiences from past lives and the consequences of their taking wrong paths, were freed to move forward into the future by experiencing a lifetime that will bring them to a Good Medicine Death.
This story begins at a time when the Universe became aware that all of the people known as the Mashodack Tribe went to sleep. Legend tells us that when their language was no longer spoken and the echo of their songs ceased to be carried on the wind that the collective memory of the northern people was erased from the face of the Earth.
The Universe missed the chatter of the Mashodack women, the laughter of the Mashodack children, the storytelling of the Mashodack men; and the distinctive melodies of the sacred songs that were once sung by all of the Mashodack Tribe.
The Universe grieved over the loss of viewing the many comforting domestic scenes. The Universe could not remember what had happened to the beloved Mashodack people. This lack of memory caused the Universe to ponder the reason for their disappearance. The Universe especially missed looking down upon the Earth to view the fires that once were lit across the ridge path of Mashodack Mountain. For now there was only a black and empty space smeared across the landscape where once lived the people of quartz and shale; water and ice. The Mashodack Tribe had been the Universes' fire keepers for the sacred Hill of Fire.
Under the auspices of seeking answers, the Universe instructed the Star Nation to send three spirit-beings to Earth to wake them up; and if that were not possible, to find answers as to their whereabouts.
The Star Nation asked if any Celestial Beings were of the mind to be chosen for the Universe's onus. But the season of happiness and contentment had previously swept across the Star Nation and none of the Celestial Beings sought a change in state; and none came forward to claim the quest. The Universe sensed the reason for this complacency and decided to send a whirlwind to scramble and spin waves of discontent throughout the celestial canopy.
The Celestial Mother looked around her perimeter and spoke these words; "Am I not the Mother of all beings?" With that said, the Celestial Mother disguised as a female human, dressed herself in a garment made from the hide of a buffalo. Before departing the Star Nation, the Celestial Mother transfigured one moon and one star into human beings. The Celestial Mother then proceeded to take the hand of her gentlest daughter; and the hand of her wisest son; traveling side-by-side to Earth. Thus, begins the mythic story of The Thunderclouds of Mashodack Mountain.


PILIUS is a unique raincoat for wheelchair users that pays particular attention to contemporary aesthetics and real functionality.
Functionality. Aesthetics. Safety. Motion. Universal Design.
The story of Pilius began a year and a half ago after winning an international creative challenge aiming at the design of fashion accessory equipment for physically disabled people who use wheelchairs. "DESIGN (DIS)ABILITY" competition was launched by RogLab in collaboration with the YHD – Association for Theory and Culture of Handicap.
After one year of testing, researching and prototyping, we have finally found a way to design a fashionable and functional raincoat, enhanced with convenient features for wheelchair users. Even though it incorporates some standard features of the raincoat, it is also customized to suit the individual's needs.
Our project is based on a proactive approach to creating a designer product that benefits those with both temporary and permanent limited mobility. People with disabilities are faced with the decision of choosing comfort and functionality over aesthetics and individuality.
We want to offer them both.
Pilius can be rolled up tightly into a discreet bag with Velcro loops that fit onto the push handles or push bar of any manual wheelchair. On the lower part of the bag are two zippers that open from the middle outwards. With a simple move, you can pull the sewn-in reflective strap and unfold the raincoat from the back of the wheelchair.
With its easy access and fast unpacking, Pilius offers effective protection from rain and the elements.
Features like a thoughtfully designed hood, extended and reinforced sleeves, customized strapping options and reflective tape that provides high-visibility, are all designed and constructed to fit the body perfectly, providing real comfort and protection.
The specially designed hood with peak has an enlarged neckline and aperture for optimized peripheral vision.
The reflective strap that's primarily used to unfold Pilius from the bag is also used for fastening the raincoat around the ankles to keep it in place.
Elastic attached on each side are used to fasten the raincoat around the backrest of the wheelchair with a plastic clip. That way the back of the raincoat creates a perfect universal fit, eliminating unwanted bulk and preventing rainwater from drenching the seat.
Pilius is cut from a technologically advanced material from the Swiss company Schoeller Textiles, which specializes in high-performance textiles widely used in active sport applications. Thanks to its special membrane technology, Pilius provides optimal protection, even in adverse weather conditions.
Click on the image to read more about the fabric.
The colour of the waterproof zipper, elastic cord, cord locks and eyelets are all well matched to create the overall unified look of Pilius.
There are no seams running across the most exposed area – shoulders; instead one seam runs up the arm and finishes in the back, following the lines of the wheelchair's backrest.
Welded seams make Pilius waterproof.
Capes that are currently available on the market, are a practical solution but they are shapeless. Pilius was thoughtfully designed by a fashion designer who took into consideration the specific needs of the individual wearing the garment.
Within designing for disabilities, where teams still tend to come exclusively from clinical and engineering backgrounds, the dominant culture is one of solving problems at the expense of aesthetics. We want to produce a highly functional and quality clothing, but maintaining the autonomy and uniqueness of the design.
The translucent fabric helps create a contemporary, urban look and emphasizes the individual style of the user.
While your favourite raincoat is out refreshing, you can enjoy the weather, because it's probably sunny.
With the two Velcro loops you can adjust the fit of the bag on different width sizes of wheelchair.
Pilius can be easily folded into the bag. For safety reasons you can attach the raincoat on the bag with a small Velcro dot so it doesn't fall on the ground while pulling it out.
We were really excited when we found out that the material is also touch-sensitive and you can operate any mobile device without even taking it out of the pocket!
After use, Pilius can be easily folded into the inside-out pocket with the reversible zipper, so it can be stored in a smaller, more compact package.
The raincoat's reinforced sleeves are designed with an extended construction with thumb-holes to protect the hands and minimize exposure to the elements, without impairing wheelchair operation.
And keeping safety well in mind we added an extra reflective tape on the back of the hood.
We approached our project with sustainability in mind from the very beginning. We wanted to include environmental goals in our product and consider the complete lifecycle of our designs. So we decided to make this key accessory using the leftover materials from Pilius – fabric and metal eyelet. Not only practical, but also a daily reminder of a nice gesture (you did)!
To tie in another special story into our concept, we also made a multifunctional velour blanket (100% polyester) to keep you warm in many ways.
First you should check which size fits you regarding your body height. In the chart below you can find the maximum bust, waist and hips measures that help you find the perfect fit.
For reference: Barbara (body height: 173cm / 5'7ft) is wearing M size Pilius and Primož (body height: 190cm / 6'2ft) is wearing an XL Pilius.
As a team we are entering this Kickstarter campaign in hope that advances in mainstream design will eventually find their way into products for people with disabilities and smaller markets that cannot afford to support the cost of their development.
With the best quality materials we are determined to produce durable, high performance clothing, while at the same time maintaining real design integrity.
Why is disability still an afterthought?
Even though it is long known that no two individuals are the same in any developmental dimension, there are still shortcomings in particular design areas. During our visitations to the rehabilitation centre, we were confronted with this fact.
With Pilius, we are trying to establish DESIGN (DIS)ABILITY brand that would pave the way for a series of - functionally and aesthetically - pleasing products for different types of disabilities. We want to go beyond universal design. Take a new approach, advocated by a wide range of users, designers, engineering teams, social sciences and humanities.
Design needs to include every body regardless of its current status as disabled or not.
The products in our campaign are prototypes, so please have tolerance for minimal changes that won't affect the overall look or functionality. If there will be any changes, they will definitely be for the better.
Because of the high quality fabrics and the design of Pilius, production will require 5 months from the end of the Kickstarter, hence the June 2016 date.
We will be extremely transparent and will update you on the status of production and shipment whenever there is something new to share.
We want to produce Pilius and all the rewards locally with manufacturing expertise and experience that we have access to.
And sure, good fortune just might play a role in our delivery timing, but the quality of our delivering product isn't about luck.
Simply put, our product is our promise to our backers. Pilius.
Donate and help us spread our vision!
Take a pro-active approach to addressing fashion to reach and serve users with physical disabilities. Most of the few fashion accessories available on the market are originally designed either for people without disabilities or as basic medical devices.
Our vision is to develop a brand that would speak to this community.
You get a thank you card signed by the designer of Pilius.
This is a key accessory for your keys!
Unique keychain made from the leftover materials from Pilius.
Not only practical, but also a daily reminder of a nice gesture you did.
To keep you fashionably warm.
Feel good about the nice gesture you did and stay warm.
Don't wait in line – order first!
Some people enjoy the rain. Others just get wet.
Two Pilius raincoats with 12$ off retail.
5 Pilius raincoats with 50$ off retail.
Order 9 and Get 10!


text:
Teachers

				Posted on

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    	No Teachers yet, why don't you create one?

redpajama_set_name: RedPajamaGithub


Ford looked to the track to improve the performance in the 2019 Mustang Shelby GT350, upgrading aerodynamics, chassis and tires, among others.
Ford Performance worked with Michelin to engineer new Michelin Pilot Sport Cup 2 tires with a new compound and model-specific tread pattern, resulting in more grip to improve straight line and lateral acceleration and braking. The 295/35 front and 305/35 tires are mounted on new 19-inch aluminum wheels.
New body work was adapted from the Mustang road-course racing cars and from the upcoming Shelby GT500. Changes include an all-new rear spoiler (further available with a Gurney flap — the small tab added to the underside of the wing to improve downforce — after launch). The race cars also provided improvements to brakes (6-piston front and 4-piston rear Brembo calipers), electric steering assist and 3-mode electronic stability control.
Upgraded MagneRide active suspension features recalibrated springs and revised damping on the shocks so that ride and handling takes full advantage of the aerodynamics and the performance tires.
And when it came time to shake down the car on the track, Ford turned to FIA World Endurance Ford GT and IMSA Mustang GT4 driver Billy Johnson, proclaiming it a more-balanced, higher performing car on straightaways and in corners.
Power comes from the exclusive 5.2-litre V-8 that delivers 526 hp and 429 lb-ft of torque, leading up to an 8,250 rpm redline. It's controlled by a Tremec 6-speed manual transmission.
The interior is more comfortable and stylish, with a purpose-built cockpit filled with premium materials (such as the machined aluminum or exposed carbon fibre applique on the instrument panel, Recaro race seats, 12-speaker Bang & Olufsen Play audio system, and Miko suede inserts or doors and seats) and the latest technology (8-inch touchscreen with Sync 3 and FordPass Connect).
New colours include Velocity Blue and Ford Performance Blue, with Shadow Black, Oxford White or Kona Blue stripes. The car will be available in early 2019, with prices including a Ford Performance Track Attack driving course.


Good Morning Most Wonderful and Thankful World Changers!!!! Most of the time people wait for the problem to be solved before they say thank you. But i say, why wait! Be grateful while you're in the midst of a problem! That would probably help you feel better anyway. When there's a problem, try to focus only on things you are thankful for. Watch that problem simply dissolve! Feel free to give thanks at anytime!
Previous Post Everyday Is A Day of Thanksgiving!!
Next Post Thanks for Life, Health, and Strength!


text:
Bathnaha  is a village development committee in Mahottari District in the Janakpur Zone of south-eastern Nepal. At the time of the 1991 Nepal census it had a population of 7210 people living in 1206 individual households.

References

Total Population - 10000
No of Voters - 3500
Employment (Govt) - 100
Employment (Pvt) - 700
Employment (Self) - 1000
Agriculture Land - 7150 acers
School - Sri Bhai. Gu. Lo. Janta Ma. Bidyalaya, Esdtd - 2011
Access Road - From Jaleshwor, Sursand (Bihar), Parihar (Bihar), Sahashram, Kataiya, Madhawa, Halkhori, Barahi

External links
UN map of the municipalities of Mahottari District

Populated places in Mahottari District


text:
Sending SMS
Receiving SMS and MMS
Program for resellers
API - information
Message length
Final statuses of the operation
Types of mobile numbers
In order to facilitate communication we have adopted certain definitions; you can find them below.
It is information with the same content sent to one or many recipients.
This is the content of the information which gets to one or many recipients. A message can consist of one or more text messages.
Text message/SMS
It is a part of a message. A message can consist of one or more SMSs; the number of text messages depends on the length of the message. There is a table further on specifying the number of SMSs a message can contain. This depends not only on the length of the message, but also on the type of the characters used.
Standard characters
A set of standard symbols whose application in the messages is treated like entering a single character. These are as follows:
@ £ $ ¥ è é ù ì ò Ç Ø ø Å å Δ _ Φ Γ Λ Ω Π Ψ Σ Θ Ξ Æ æ ß É ! " # ¤ % & ' ( ) * + , - . / 0 1 2 3 4 5 6 7 8 9 : ; < = > ? ¡ A B C D E F G H I J K L M N O P Q R S T U V W X Y Z Ä Ö Ñ Ü § ¿ a b c d e f g h i j k l m n o p q r s t u v w x y z ä ö ñ ü à
Standard characters are as well:
^ { } [ ] ~ \ | € and ,but these are treated in the messages as double characters. Special characters are not included in the standard characters set. Using even one special character in a message means that each character, including standard characters, is treated as double characters; this makes the message shorter.
wAll the characters not included in the standard characters set. Using even one special character in a message means that each character, including standard characters, is treated as double characters; this makes the message shorter.
All the information messages in the system are coded with the UTF-8 coding. Such coding is also required for API triggers in order to correctly support the signs out of the standard ASCII range.
Depending on the number of the used characters, as well as the type of characters in the messages (standard/non-standard characters), a message can contain more than one SMS. It is important to remember that using even one non-standard character in the message causes the length of the message to shrink.
The length of the message (not including special characters) vs. the number of SMSs included.
Massage length
Number of SMSs included
from 1 to 160 1
from 161 to 306 2
The table below shows the number of SMSs included if there is even one special character in the message .
The length of the message (including special characters) vs. the number of SMSs included.
from 1 to 70 1
from 71 to 134 2
Delivery status is returned every time after sending a message through HTTP/SOAP SSL API. This is a confirmation whether the message was sent correctly. A list of possible returned statuses along with descriptions below:
Statuses returned when texting
001 Sent correctly
002 Message correctly forwarded to sending, but due to technical reasons will be sent at a later time (concerns FasterSMS)
011 Necessary parameters have not been given, no GET/POST data.
021 Wrong log-in or password
022 Insufficient fund in the account to complete sending.
023 Problem sending message, contact Customer Service.
031 Sender field too long (maximum 16 characters for numerical sender and 11 characters for alphanumerical sender).
032 You haven't given the recipient of the message or the recipient given is incorrect (incorrect/nonexistent mobile number/landline number).
033 You haven't given the message content.
034 Past time is given a preferred sending time.
035 The number of own IDs is bigger than the number of the recipients of the sent message.
036 MaxSMS type is selected, but the sender is not specified (maximum 11 alphanumeric characters).
037 You only allow one-SMS-messages and this message is longer.
038 The content of the message exceed the technically allowed length (more than 4 SMSs in one message).
039 You have selected FasterSMS and at the same trying to send a message to more than one recipient which is not allowed (FasterSMS is used to send single text messages, for example with one-time password).
040 Sender name is not registered, contact the Customer Service.
080 IP address which triggered API is not on the list of authorized address allowed to use the API. Log in to the SMS Panel configure the API settings.
041 The message contains characters out of the allowed UTF-8 characters range.
091 Error connecting to base. Contact the PromoSMS company.
092 Error sending messages. Contact the PromoSMS company.
Message delivery Reports
Each message can have one kind of statues dedicated. Their full description is included in the table below.
Kinds of statuses
0 The message has not been forwarded to sending yet. This status is possible immediately after ordering sending (messages are forwarded to the service provider on average every 15 seconds) or in case of messages which are scheduled to be sent in the future (time parameter while sending).
4 lub 8 The message has been forwarded to the service provider. At this moment the PromoSMS platform is waiting for completing the order. Status number 8 can be compared to sending a text message from a phone when the phone has already sent the message, but it is not confirming the sending/failure to send from the service provider. Moreover, if the recipient's phone is off, and the provider tried to deliver the message correctly, this kind of status is to be expected as well.
1 This status means that the message has been delivered to the recipient's mobile.
2 lub 16 The message has not been delivered. There might be a few reasons. The most likely are: the recipient's number is incorrect, the recipient's phone has been off for a long time and the message expired.
There is a list of the types of mobile numbers recognized by the system in the table below.
Mobile numbers type description
Number type
1 Landline number
2 Mobile number
3 It is possible in some countries that the number is a landline and a mobile at the same time.
4 Toll-free number
5 Higher toll number.
6 The cost of connection is shared between the caller and the recipient (for example the 801 type of number).
7 VoIP number
8 Personal number, it can be a mobile or a landline at the same time (see here: http://en.wikipedia.org/wiki/Personal_Numbers )
9 Pager
10 Universal Access Numbers or Company Numbers (one company number but the call may be transferred)
10 or -1 Incorrect or other number, unidentified type of number.
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THORNTON, Colo. – Construction crews working on a new public safety facility in the Colorado city of Thornton uncovered a rare dinosaur fossil, according to KDVR.
Crews working at the site found what appeared to be a triceratops skull and skeleton on Friday.
Scientists from the Denver Museum of Nature & Science went to the site and confirmed the find.
"This is probably one of only three skulls of triceratops found along the Front Range area," Sertich said.
Most fossil finds along the Front Range – part of the Southern Rocky Mountains – are from the Ice Age, between 10,000 and 12,000 years old, but this fossil is much older, and much rarer, according to Sertich.
Construction crews have stopped work in the area of the fossil, officials with the City of Thornton confirmed.
"The DMNS scientists will stabilize the area, carefully expose the fossil, look for any other bones that remain uncovered, and safely extract them," city officials stated.
Scientists hope to eventually house the fossil at the Denver Museum of Nature and Science.


Peter de Smet, Pavel Kurfürst, Frank de Leeuw, Nina Benešová, European air quality maps of PM and ozone for 2011 and their uncertainty. ETC/ACC Technical Paper 2013/13. 2013.
For references, please go to https://www.eea.europa.eu/data-and-maps/indicators/exposure-of-ecosystems-to-acidification-14/jan-horalek or scan the QR code.


The use of fleshly incentives to draw people to worship services is becoming more and more common. One church offers free cokes, doughnuts, and balloons to its bus riders. Another offers a prize to the child who brings the most visitors. Still another uses some sports figure or entertainer to attract a crowd. Dinners and socials; elaborate church buildings; "Friendliest church in town" or "Fastest-growing church in town" advertising; the list of gimmicks is almost endless.
A study of I Corinthians, chapters 1 and 2, suggests that the people of our generation are not the first to demand fleshly incentives. The Jews and Greeks of Paul's day demanded them. "For Jews request a sign, and Greeks seek after wisdom" (I Corinthians 1:22). Paul could have produced both, but he refused to do so: "But we preach Christ crucified, to the Jews a stumblingblock and to the Greeks foolishness, but to those who are called, both Jews and Greeks, Christ the power of God and the wisdom of God" (I Corinthians 1:23-24).
Paul recognized the fact that some people are just not "convertible": "For you see your calling, brethren, that not many wise according to the flesh, not many mighty, not many noble, are called" (I Corinthians 1:26). Why are such infrequently called? Because the majority place their trust in the flesh rather than in God. They are fleshly-minded. And Paul was not about to coax fleshly-minded, "unconvertible" people "into the church" by the use of signs, wisdom, excellency of speech, enticing words, or any other fleshly incentive. To do so would result in getting their names on a "church roll," but not in bringing them to Christ to the saving of their souls.
If Paul refused to use signs and wisdom as fleshly incentives, what would have been his reaction to the use of cokes and doughnuts? If he came "not with excellence of speech or of wisdom" (I Corinthians 2:1), what would he have said concerning attempts to attract crowds through the use of sports figures and entertainers? If Paul, led by the Holy Spirit, followed a "no fleshly incentive" policy, should that not be our policy? And should we not always be able to say with Paul, "For I determined not to know anything among you except Jesus Christ and Him crucified" (I Corinthians 2:2)?


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The  is a railway line operated by the East Japan Railway Company (JR East). It links Katori Station with Kashima Soccer Stadium Station by crossing and then following the Tone River, at the border between Chiba Prefecture and Ibaraki Prefecture.

Operation
Katori Station is on the Narita Line, and all trains of the Kashima Line run through from/to its neighboring station, Sawara, or beyond it, but all trains terminate at Kashima-Jingū. Only Kashima Rinkai Railway Ōarai Kashima Line trains run from here to Kashima Soccer Stadium and Mito Station. Kashima Soccer Stadium Station is only temporarily operated when football matches are held at Kashima Soccer Stadium, the home stadium of Kashima Antlers in J.League (Japan Professional Football League).

From Kashima Jingu to Sawara, JR East local trains run approximately once per 1–2 hours. Some Narita Line through service train runs beyond Sawara to Narita. Each day, one through service Sōbu Line (Rapid) train runs to Tokyo Station (weekdays) or Ōfuna Station (weekends and holidays) in the morning, and from Kurihama Station (weekdays) or Tokyo Station (weekends and holidays) in the evening.

Until 2015, the Limited Express Ayame service ran between Tokyo Station and Kashima Jingu once in a day, from Kashima Jingu in every morning, from Tokyo in every night, and stopped all stations on the Kashima Line. From Kashima-Jingū and Mito, Oarai Kashima Line local or rapid diesel trains run approximately once an hour. Normally, no passenger train stops at Kashima Soccer Stadium, except when football matches are played in the stadium.

JR Freight operates trains on the line, from Tokyo area to the Kashima Rinko Line. The trains change its directions at Kashima Soccer Stadium Station.

Stations

History
This line was planned as the main mass transportation method within the Kashima Industrial Zone along the southern coast of Ibaraki Prefecture, to connect with the Tokyo Metropolis.

20 August 1970 – Newly operated between Katori and Kashima-Jingū (14.2 km), as JNR Kashima Line.
12 November 1970 – Newly operated between Kashima-Jingū and Kita-Kashima (3.2 km), as the freight line.
24 October 1974 – The line was electrified.
March 1978 – Jet airplane fuel transport service was started from Kashima Rinkai Kashima Rinko Line (owned by Kashima Rinkai Railway), via Kita-Kashima Station, to Tsuchiya Freight Terminal Station, near Narita Station, to supply New Tokyo International Airport.
25 July 1978, Passenger service was begun between Kashima-Jingū and Kita-Kashima, as the beginning of passenger service in Kashima Rinko Line.
8 August 1983 – Jet fuel freight line ended (pipelines came on service).
1 December 1983 – The passenger service between Kashima-Jingū and Kita-Kashima was abolished, which was started in 1978.
14 March 1985 – The passenger service was re-opened in the section between Kashima- Jingu and Kita-Kashima, as the opening of Kashima Rinkai Oarai Kashima Line.
1 April 1987 – JR East succeeded this line from JNR.
12 March 1994 – Kita-Kashima Station was renamed to Kashima-Soccer-Stadium Station, and it served as a temporary station for football spectators in Kashima Stadium.
2 June 2002 – 2002 FIFA World Cup game, Argentina – Nigeria was played in Kashima Stadium. JR East operated special trains between Chiba Station to Kashima-Soccer-Stadium Station, as special rapid trains.

Rolling stock
E131 series 2-car EMUs (since 13 March 2021)

Sōbu Line (Rapid) through service
E217 series 4-car EMUs
E235-1000 series 4-car EMUs

Past
113 series EMUs
183 series EMUs (Ayame limited express services)
209-2000/2100 series 4-car EMUs (until 12 March 2021)
E257-500 series (Ayame limited express services until 13 March 2015)

References

External links

Lines of East Japan Railway Company
Railway lines in Chiba Prefecture
Rail transport in Ibaraki Prefecture
1067 mm gauge railways in Japan
Railway lines opened in 1970


The Housewife scores a cameo on Days of Our Lives.
Kyle Richards is no stranger to the small screen: before taping began for The Real Housewives of Beverly Hills, Kyle was an established actress and a movie and television star who appeared as a fixture on Little House on the Prairie back in the '70s. Kyle's flexing her acting wings once again on the iconic soap opera Days Of Our Lives!
We've got a quick clip of Kyle's cameo here courtesy of Entertainment Tonight, and it's easy to see that she's in her element right off the bat. It doesn't hurt that she's playing the role of a Casey McGraw, a fashion-forward modeling agent who shares an appreciation for sharp looks and beautiful things.
What do you think of Kyle's Days Of Our Lives performance? Has she still got her acting chops? Tell us in the comments.


text:
222 U.S. 39 (1911), 56, Troy Bank v. G. A. Whitehead & Company, Inc.
Document Cited authorities 8 Cited in 248 Precedent Map Related
Docket Nº: No. 56
Citation: 222 U.S. 39, 32 S.Ct. 9, 56 L.Ed. 81
Party Name: Troy Bank v. G. A. Whitehead & Company, Inc.
Case Date: November 06, 1911
Court: United States Supreme Court
222 U.S. 39 (1911)
32 S.Ct. 9, 56 L.Ed. 81
Troy Bank
G. A. Whitehead & Company, Inc.
APPEAL FROM THE CIRCUIT COURT OF THE UNITED STATES
FOR THE WESTERN DISTRICT OF KENTUCKY
When two or more plaintiffs, having separate and distinct demands, unite for convenience and economy in a single suit, it is essential that the demand of each be of the requisite jurisdictional amount; but when several plaintiffs unite to enforce a single title or right, in which they have a common and undivided interest, it is enough if their interest collectively equal the jurisdictional amount.
The Circuit Court has jurisdiction of a suit brought by several plaintiffs to enforce a vendor's lien equally securing notes aggregating more than $2,000 held by them and which neither can enforce in the absence of the other, even though the claims of each plaintiff is less than $2,000.
184 F. 932 reversed.
The facts, which involve the question of whether the sum or value of the matter in dispute was sufficient to give the circuit court jurisdiction, are stated in the opinion.
VANDEVANTER, J., lead opinion
MR. JUSTICE VAN DEVANTER delivered the opinion of the Court.
This was a suit in equity wherein the jurisdiction of the circuit court was invoked on the ground of diverse citizenship, and the sole question now presented for decision
is whether the sum or value of the matter in dispute exceeded $2,000, exclusive of interest and costs, as required by the Act of August 13, 1888, c. 866, § 1, 25 Stat. 433. The facts are these:
Upon a sale of land situated in the Western District of Kentucky, the vendor lawfully reserved a vendor's lien for the unpaid portion of the purchase price, for which he took two promissory notes of $1,200 each, payable in one and two years. Shortly thereafter, the notes were assigned to the present appellants, one to each, and by the law of Kentucky the vendor's lien passed to the assignees, as a common security for the payment of both notes, without any priority of right in either assignee. After the maturity of the notes, both remaining wholly unpaid, the assignees jointly brought this suit to enforce the vendor's lien. They and their assignor were citizens of Indiana, and the defendant, who acquired the land with notice of the lien, was a citizen of Kentucky.
By a demurrer to the bill, the defendant...


Chronic fatigue syndrome (CFS) is a complex, multi-symptom illness with a multisystem pathogenesis involving alterations in the nervous, endocrine and immune systems.
Abnormalities in stress responses have been identified as potential triggers or mediators of CFS symptoms. This study focused on the stress mediator neuropeptide Y (NPY). We hypothesized that NPY would be a useful biomarker for CFS.
Plasma NPY was elevated in CFS subjects, compared to controls (p = .000) and to GWI cases (p = .000). Receiver operating characteristics (ROC) curve analyses indicated that the predictive ability of plasma NPY to distinguish CFS patients from healthy controls and from GWI was significantly better than chance alone. In 42 patients with CFS, plasma NPY had significant correlations (<0.05) with perceived stress, depression, anger/hostility, confusion, negative thoughts, positive thoughts, general health, and cognitive status. In each case the correlation (+ or -) was in the anticipated direction.
According to the 1994 international research case definition , as modified according to Reeves, et al , chronic fatigue syndrome (CFS) is an illness characterized by 1) the presence of persisting, debilitating fatigue that does not resolve with bed rest, and lasts for at least six months resulting in severe impairment in daily function; 2) by symptoms and disability that cannot be ascribed to any other medical and psychiatric conditions. Diagnosis relies in large part on behavioral markers, either patients' self-reported symptoms or observations by clinicians. Laboratory diagnostic and screening tests are not widely available.
In 60 to 80% of published samples, CFS presented with acute onset of illness, with systemic symptoms similar to influenza infection that did not subside . The sudden onset, the symptoms of myalgia, arthralgia, sore throat and tender lymphadenopathy support theories of infection induced illness [3, 4]. Published reports both confirm and deny associated microbial infections, reactivation of latent herpes virus infections and/or retrovirus infections in CFS [5–14].
CFS is responsible for significant morbidity and occurs in an estimated 0.42% of people, predominately female, in the United States and worldwide [15, 16]. Prior work strongly suggests this complex, multi-symptom illness has a multi-system pathogenesis that involves the nervous, endocrine and immune systems [3, 17–21]. Abnormalities in stress responses have been identified as potential triggers or mediators of CFS symptoms [22–24].
Neuropeptide Y (NPY) is found in both the central and peripheral nervous systems. In the peripheral nervous system, NPY is concentrated in and released from sympathetic nerve endings, either alone or with catecholamines. Irwin reported NPY increased in depressed and stressed subjects, and suggested that "circulating levels of this neuropeptide serves as a tonic measure of sympathetic activity". NPY release follows stress such as strenuous exercise , panic disorders , and cold exposure . In the periphery, NPY is activating and stimulates the stress response, but in the brain, NPY is anxiolytic, inhibitory of sympathetic activity and causes lowering of blood pressure and heart rate [29, 30]. Concentrations of NPY in the brain are higher than other neuropeptides, particularly in the limbic system, including the amygdala and the hypothalamus, all areas of the brain involved with emotion [31, 32].
Given these reports, it seemed likely that plasma NPY would be elevated in CFS. Elevated NPY would be anticipated to correlate with psychological measures of stress and other aspects of CFS symptoms. However, we could find no such studies. There is a clear need for CFS biomarkers that are useful in diagnosis, in defining patient subgroups and in therapeutic trials. We tested and confirmed the hypotheses that elevation of peripheral NPY occurs in CFS and that elevation of NPY is associated with severity of stress, negative mood and clinical symptoms.
Abnormalities in stress responses have been identified as potential triggers or mediators of CFS symptoms. This study focused on the stress mediator neuropeptide Y (NPY). The aim was to examine the potential of plasma NPY as a biomarker for stress and symptom severity in CFS.
All subjects were participants in research studies taking place between 2002 to 2010 at the University of Miami or the Miami Veterans Administration Health Care Center (funded by NIH, VA, Chronic Fatigue and Immunodeficiency Syndrome Association or the University of Miami).
Chronic fatigue syndrome patients (n = 93; age 18 to 60, mean age 44 +/- 9 S.D.; median age 46, 25 percentile 38, 75 percentile 50; 83% female) were drawn from the University of Miami Miller School of Medicine CFS and Immunodeficiency Clinic after they were diagnosed with CFS, using the 1994 international research case definition , as modified according to Reeves, et al . This requires 4 of 8 symptoms including exercise induced relapse, myalgia, arthralgia, headache of a new and different type, nonrestorative sleep, cognitive complaints, sore throat and tender lymph nodes. Exclusion criteria included any active medical condition that could explain the presence of chronic fatigue, including diabetes, the current use of immunomodulatory or antibiotic medications, and a past or present psychiatric diagnosis of psychosis (e.g., schizophrenia), dementia, major depressive disorder with psychotic or melancholic features, bipolar disorder, anorexia or bulimia nervosa, or alcohol/substance abuse disorder within two years of the onset of the fatigue or anytime thereafter. In agreement with published samples, the majority of CFS cases presented with a history of acute onset of illness, with systemic symptoms similar to influenza infection that did not subside .
Sedentary healthy controls, with no active medical or psychiatric conditions, immunomodulating medications or alcohol/substance abuse, (n = 100; 84% female; mean age 41 +/- 10 S.D.; median age 41, 25 percentile 35, 75 percentile 49) were from NIH or VA funded studies conducted by one or more of the investigators in this study.
A comparison group of patients with a fatiguing, multi-symptom illness, GWI, was also included in the study (N = 37; 29% female, mean age 44 +/- 7; median age 42, 25 percentile 38, 75 percentile 48). The inclusion criteria for GWI, derived from the case definition by Fukuda et al , was: a veteran deployed to the theater of operations for Operation Desert Storm between August 8, 1990 and July 31, 1991 with one or more symptoms present greater than 6 months from at least 2 of the following: fatigue; mood and cognitive complaints; and musculoskeletal complaints (joint pain, stiffness or muscle pain). These subjects had no active medical or psychiatric conditions, immunomodulating medications or alcohol/substance abuse.
Morning, non-fasting blood samples were collected, prior to the collection of clinical or and psychometric data. The blood was collected into ethylenediaminetetraacetic acid and all of the samples for this study were delivered to University of Miami clinical immunology laboratory within 2 hours. The laboratory received and assayed the samples in a blinded fashion. Plasma was separated from cells within 2 hours of collection, aliquoted into cryovials and stored at - 80°C until assayed. The length of time of storage at -80°C varied from 6 months to 5 years for the samples in this study. Samples were thawed only one time.
Plasma NPY was measured by direct assay without extraction using a competitive radioimmunoassay (RIA) from ALPCO Diagnostics (Salem, NH). The antiserum was raised against synthetic NPY conjugated to bovine thyroglobulin and cross-reacted less than 2.0% with human peptide YY. The NPY in standards and samples competed with 125I-labeled NPY in binding to the antibody. 125I-NPY bound in reverse proportion to the concentration of NPY in standards and samples. Antibody-bound 125I-NPY was separated from the unbound fraction with a double antibody coupled to the solid phase. The radioactivity of the antibody-bound 125I-NPY was then determined. The measurable range of the assay was 9.4 - 300 pmol/L and sensitivity was 3 pmol/L. The manufacturer reported a mean value of 74 pmol/L (SD = ± 15) and a range of 36-120 pmol/L for 109 healthy controls (ages 20-60 years). The intra assay coefficient of variation (CV%) was 4.75%. The inter assay CV% was 8.4%. All samples were assayed in duplicate. All assays were done in the same laboratory. Individual runs were mixtures of samples from the 3 cohorts in the study. A set of control samples were included in each assay.
The Medical Outcomes Survey Short Form-36 (SF-36) assessed health-related quality of life including: limitations in social activities, emotional problems and general health .
The Perceived Stress Scale (PSS) was used as a measure of stress .
The Fatigue Severity Inventory (FSI) was designed for measuring fatigue severity. Items in the inventory are statements related to fatigue perceptions .
The COPE, a multidimensional coping inventory, was used to assess the different ways in which people respond to stress . Subscales for denial, behavioral disengagement and self-blame were used.
The Quality of Life Scale (QOL) total score measured general well-being, cognitive functioning, affective status, physical health status and social activity .
The Profile of Mood States (POMS) a measure of psychological distress consists of 65 adjectives rated on a 0-4 scale that are comprised of subscales measuring 'depression-dejection', 'tension-anxiety', 'anger-hostility', 'confusion-bewilderment', 'vigor-activity' and 'fatigue-inertia' .
The Adult Temperament Questionnaire (ATQ) is a 77-item self-report instrument used for assessment of positive and negative thoughts and is a measure of stre ss that is possibly predictive of stress-related health problems .
The Cognitive Capacity Screening Examination (CCSE) was used to quantify the general cognitive status of subjects .
The Beck Depression Inventory (BDI) is a 21-question multiple-choice self-report inventory used to measure severity of depression .
These instruments were completed by the CFS patients on the same visit as the blood draw.
This study was approved by the University of Miami Institutional Review Board. All subjects signed a written informed consent approved by the University of Miami Institutional Review Board. All consented to blood draw and to the availability of the stored samples for additional bioassays. Participants were English speaking with at least an 8th grade education to ensure they were able to comprehend the informed consent as well as read and complete the questionnaires.
The Mann-Whitney U test was used to determine the magnitudes of between-group (case-control) differences. Pearson correlations were calculated for the psychosocial measures of disease severity and plasma NPY in 42 CFS cases. Values of p < 0.05 were considered statistically significant. The diagnostic accuracy of NPY was assessed in terms of true positive (sensitivity) versus true negative (1-specificity) using nonparametric receiver operating characteristics (ROC) analyses  available in the Statistical Package for Social Sciences (SPSS) software for Windows (SPSS Inc, Chicago, IL). The nonparametric ROC plot uses all of the data, makes no parametric assumptions and provides unbiased estimates of sensitivity and specificity, indicating the ability of a test to discriminate between two alternate states of health, in this case, CFS cases and healthy controls and CFS cases and GWI cases. The calculation of the area under the curve (AUC) provided a convenient way to determine the ability of the NPY assay to distinguish these groups. An AUC = 0.5 indicates that the test shows no difference between the two groups while AUC = 1.0 is found if the test gives a perfect separation between groups.
Plasma NPY (pmol/L) was elevated in CFS subjects, compared to controls (mean for CFS patients = 102.4 +/-49.2, mean for controls = 79.8 +/-34.9, p = .000). CFS cases were also elevated when compared to GWI cases (mean for GWI patients = 75.1 +/- 38.1, p = .000). The distribution of plasma NPY values for the CFS cases, the healthy controls and for GWI are shown in Figure 1. ROC curve analyses of CFS and controls indicated that the predictive ability of plasma NPY was significantly better than chance alone (see Figure 2, Table 1). ROC curve analysis showed that NPY also distinguished GWI from CFS (Figure 3, Table 2). The coordinates of the curves (COC)) provide the entire spectrum of sensitivity/specificity pairs and a complete picture of test accuracy (see Additional files 1 and 2).
The panels show the histogram of plasma NPY values for the Chronic Fatigue Syndrome cases (CFS), the healthy controls (HC) and the Gulf War Illness cases (GWI).
ROC curve analyses of plasma NPY (red curve) as a predictor of CFS, comparing CFS with healthy controls. Larger values were associated with CFS cases. The 45 degree line (green) indicates the theoretical plot of a test with no discrimination between CFS and controls.
ROC curve analyses of plasma NPY (blue curve) as a predictor of CFS, comparing CFS with GWI. Larger values were associated with CFS cases. The 45 degree line (green) indicates the theoretical plot of a test with no discrimination between CFS and GWI.
In this study, we found that the stress hormone, NPY, was statistically elevated in plasma from CFS cases compared to healthy controls - and to a group of patients with another fatiguing, multi-symptom illness, GWI. This later finding was unexpected. However, it might be explained by gender distribution, which was very different between CFS and GWI. ROC analysis indicated that plasma NPY has promise as a biomarker for distinguishing CFS both from healthy controls and .from related fatiguing illnesses. Our finding that NPY positively correlated with perceived stress, anger, depression, negative thoughts and maladaptive coping in patients with CFS suggests that NPY will be useful in defining subsets of patients for clinical trials and as a measure of therapeutic effects.
Abnormalities of the stress response are potential triggers or mediators of CFS symptoms . Acute stress induces a fight-and-flight response that prepares the organism for coping with environmental challenge . Sympathoadrenal activation during the stress response results in increased release of epinephrine (E) and norepinephrine (NE) from the adrenal medulla, increased NE and NPY release from the sympathetic nerve endings and changes in blood flow to a variety of organs . Activation of the hypothalamic-pituitary-adrenal (HPA) axis results in increased secretion of glucocorticoids from the adrenal cortex .
Glucocorticoids regulate immune cell reactions to the stressor. In the brain, stress responsive neurotransmitter systems, in interaction with glucocorticoids, modulate affect, cognition and anxiety, and suppress behaviors that are inadequate for the situation, such as eating and reproduction. Increased noradrenergic activity in the brainstem increases vigilance and alertness and promotes memory for threatening stimuli . These acute stress responses represent regulatory mechanisms that are critical to survival and adaptation of the species. Dysfunction in the regulatory capacity or interplay of these systems, as a potential consequence of dispositional risk or physical, chemical or emotional challenges, might plausibly exacerbate symptoms of CFS.
Immune activation and inflammation are postulated to be principle components in the pathophysiology of CFS [19, 20, 51]. Inflammatory responses are controlled by the HPA axis network that involves corticotropin-releasing hormone (CRH), adrenocorticotropic hormone (ACTH) and cortisol. Normally cortisol induces a down-regulation of inflammation. However, this mechanism is disrupted in the typically hypocortisolic CFS patient . Broderick and colleagues propose that this disruption results not only from the possible failure of individual neuro-immune components but also involves a spontaneous restructuring of the control network . Van Houdenhove and co-workers have formulated the hypothesis that the HPA axis hypofunction in CFS reflects a fundamental and persistent dysregulation of the neurobiological stress system . Dysautonomic conditions (e.g., neurally mediated hypotension or orthostatic intolerance) have been reported in CFS patients as well as the related syndrome, GWI [54, 55].
A recent study from our group demonstrated reduced stroke volume and cardiac output in more severely afflicted CFS patients . Although we did not measure cortisol in the present study, we and others reported that moderate hypocortisolism occurs in CFS, and that it is of clinical relevance [57, 58]. For example, CFS cases with low cortisol have a poorer response of CFS cases to cognitive behavioral stress management . Of interest is the finding of Kempna, et al. , that NPY inhibits the production of cortisol in human adrenal H295R cells via the Y1 receptor. Antonijevic and colleagues showed that administration of NPY reduced cortisol secretion during night hours in healthy subjects . In contrast, a series of experiments by Morgan, et al. demonstrated that acute, uncontrollable psychological stress elevated plasma NPY as well as plasma cortisol in healthy subjects [61, 62].
Recently, our group reported that soluble as well as cell surface associated dipeptidyl peptidase IV (DPPIV) is decreased in CFS cases relative to controls . NPY's biologic effects require interaction with its receptors. Native NPY 1-36 in the periphery is a major mediator of stress, responsible for prolonged vasoconstriction via Y1 receptors . By cleaving the N-terminal Tyr-Pro dipeptide from NPY, DPPIV generates the Y2/Y5 receptor agonist NPY 3-36, that loses its affinity for the Y1 receptor and is angiogenic and inhibitory of NE release [30, 63]. The low DPPIV observed in CFS coupled with high NPY would favor the Y1 receptor agonist form of NPY.
Another consideration of interest regarding NPY and CFS is the possibility of chronic viral infection in some patients. Du, et al , recently described increased NPY expression in the central nervous system (CNS) of mice following infection with a neurovirulent polytropic retrovirus. This virus infects macrophages and microglial cells resulting in production of proinflammatory cytokines , including interleukin 1 alpha (IL-1α), IL-β, and Il-6 known to be elevated in CFS . Viral triggers such as EBV and HHV6 have long been suspected of involvement in the onset and persistence of CFS [3, 5, 6]. Evidence of xenotropic murine leukemia virus - related virus (XMRV) in peripheral blood mononuclear cells (PBMCs) in the majority of CFS cases, but not controls, supported the viral infection hypothesis . This report by Lombardi, et al was followed by 4 subsequent reports of failure to detect any murine leukemia virus (MLV)-related virus gene sequences in blood from CFS patients [12, 14, 66, 67] and one report of MLV-like virus gag gene sequences, but not XMRV, in 86.5% CFS cases compared with only 6.8% of healthy volunteer blood donors .
An obvious limitation of this study is that the samples represent a single point in time. We are presently conducting longitudinal studies. As Broderick and colleagues have pointed out, biomarkers measured in human subjects tend to be highly variable. These indicators are parts of a complex and integrated system and their inter-dependency must be addressed. The effect of medications such as cholesterol lowering, pain or anti-depression on plasma NPY is not known. However, cholesterol-lowering drugs are not well tolerated in CFS patients. Patients on opioid pain medications were excluded from the study. The effect storage of plasma for up to 5 years at -80°C on RIA detectible NPY is not known.
This study is the first in the CFS literature to report that plasma NPY is significantly elevated over healthy controls and also over a comparision group, patients with GWI. The elevation of NPY in CFS cases is associated with severity of stress, negative mood and clinical symptoms. The pattern, in some CFS cases, of high NPY noted here, along with previously observed low DPPIV and hypocortisolism [20, 57, 58] supports the hypothesis of HPA axis dysregulation in CFS. Duration of this illness typically exceeds 10 years. Persistence is likely to involve complex interaction of immune, autonomic and neuroendocrine regulation and remains poorly understood. Investigation of CFS biology has focused on the detailed characterization of individual neuroendocrine and immune components taken in isolation. Current CFS treatments are directed at reducing symptom severity but no cure exists for this condition. In a review of CFS, published in Lancet, Prins, et al. stated: "Techniques such as bioimaging and proteomic strategies, and perhaps a systems biology approach, should be applied to try to elucidate such complicated interactions". It is clear that further understanding of disease mechanisms and development of effective treatments will require more than a list of the abundance of gene products, proteins or cells. These various cellular and molecular components are highly inter-dependent. Our research group has undertaken a systems biology approach . We are presently incorporating data from plasma NPY measurements, along with other plasma and cellular biomarkers into a network analysis.
The renewed interest in viral infections in CFS suggests further studies. It is possible that NPY is induced by such infections. As reliable assays become available it will be important to determine the relationship of plasma NPY to potential pathogens.
Mary A Fletcher and Nancy G Klimas contributed equally to this work.
MAF and NGK conceived of the study, participated in its design and coordination, performed the statistical analysis and drafted the manuscript; GI and MA participated in study design; MR developed the NPY assay; NGK and SL participated in patients' diagnosis and assessment; ZB and JH participated in subject recruitment and data management; XRZ carried out the immunoassays; MAF, NGK, MA, SL and BH participated in cohort recruitment; GB evaluated the design and data analysis. All authors critically read and approved the final manuscript.


GreyGrey Designs: Pomanders are the New Black.
Pomanders are the New Black.
Like my pomanders? Want some of your own?
Message me on my Etsy Shop for pricing details on custom orders!
OR, you can buy these!
They are for sale on my shop right now!
Those pomanders are simply stunning. Unique & fabulous. Love.
yours turned out great! I made one for my wedding last year and it held up the day off, but 1 year later some of the sunflowers have fallen off.


text:
Q: How can a program detect that Ubuntu is running as a virtual machine? I am trying to run a program via Ubuntu 16.04 as a Virtualbox VM.
The binary of this program checks if it's running on a virtual machine, and does something different on a VM than if it is on a given computer.
How can I know what the binary is querying? Can I use something like strace or ldd for this?
I would like to be able to run the binary as if it was on a real machine, not a VM. I presume there must be a way to change what's reported by the Ubuntu 16.04 when the binary queries it.

A: People and apps have started to code dmidecode parsing, special instruction handling (vmware) and other things. But often such code gets outdated no more matching new versions and virtualization technologies.
IMHO by far the most reliable way is to rely on the nowadays ubiquitous systemd and just call systemd-detect-virt
The benefits are clear, many VM and container types are already implemented, you get updates along new systemd versions and have less own code that you have to maintain.

redpajama_set_name: RedPajamaStackExchange


text:
We See Retirement Differently
Gardens and Allotments
Hollins Hall has won Gold for the last 6 years and in 2019 Gold and also Best in Category.
Hollins Hall is proud to be a multi awarded best in category in the annual Yorkshire in Bloom competition. We are the current holder of both the Gold Award and Best in Category (Medium Businesses) Winner. Please enjoy reading the Judges' comments from last year's competition below:
'As you drive down to the Hall you are greeted on both sides by immaculately maintained grounds. Opposite the entrance, there is a more formal area of planting, again immaculately maintained and with the key features of a waterfall and pleached limes. The gardens have been redeveloped by David Hullah, the works have been excellently designed and planned to complement the site and the Hall. The Residents are encouraged to get involved in creating their own plots with the help of David, who willingly listens to their ideas and implements these and has clearly built up an excellent relationship with the residents and goes that extra mile to ensure the resident's wishes are met.
Tubs are well situated in areas around the Hall to add interest and are well balanced for colour and plant choice. David has also created, as a result of resident's requests a vegetable plot, which has proved successful, alongside the vegetable plot is a small orchard and wildlife area which gives a different aspect to the more formal areas. A very big thank you to David for escorting us around the grounds and he should be rightly proud of what he has achieved over the years. When viewing properties on the site the judges both agreed, a major factor for purchasing a property is the immaculately kept grounds.'
Hollins Hall, Lund Lane, Killinghall, N Yorks, UK – Blue Plaques on Waymarking.com
Designed by TPSL
Hollins Hall Harrogate


text:
package org.uclab.mm.datamodel.sc.dataadapter.testcases;

import static org.junit.Assert.*;

import java.util.ArrayList;
import java.util.List;

import org.junit.Test;
import org.uclab.mm.datamodel.AbstractDataBridge;
import org.uclab.mm.datamodel.DataAccessInterface;
import org.uclab.mm.datamodel.DatabaseStorage;
import org.uclab.mm.datamodel.sc.Recommendation;
import org.uclab.mm.datamodel.sc.dataadapter.RecommendationAdapter;

/**
 * This is a class for testing the insertion, fetching, and update of Recommendation
 * @author Taqdir Ali
 *
 */
public class RecommendationAdapterTest {

	/**
	 * This is function for testing the insertion, fetching, and update of Recommendation
	 */
	@Test
	public void test() {
		/* Preparing input object for insertion*/
		Recommendation objOuterRecommendation = new Recommendation();
		Recommendation objInnerRecommendation = new Recommendation();
		List<Recommendation> objListRecommendation = new  ArrayList<Recommendation>();

		objOuterRecommendation.setRecommendationIdentifier("A0001");
		objOuterRecommendation.setSituationID(22244L);
		objOuterRecommendation.setRecommendationDescription("testing for unit testing");
		objOuterRecommendation.setRecommendationTypeID(1);
		objOuterRecommendation.setConditionValue("condValue");
		objOuterRecommendation.setRecommendationLevelID(1);
		objOuterRecommendation.setRecommendationStatusID(1);
		objOuterRecommendation.setRecommendationDate("2016 12 12 01:30:01");

		/* Testing of insertion function*/
		 DataAccessInterface objDAInterface = new RecommendationAdapter();
         AbstractDataBridge objADBridge = new DatabaseStorage(objDAInterface);
         List<String> lstResponse = objADBridge.SaveRecommendation(objOuterRecommendation);
         if(lstResponse.size() == 2)
         {
        	 /* Testing of fetching function*/
        	 objInnerRecommendation.setUserID(2L);
        	 objInnerRecommendation.setRequestType("ByUserOnly");
        	 DataAccessInterface objDAInterfaceRetrieval = new RecommendationAdapter();
             AbstractDataBridge objADBridgeRetrieval = new DatabaseStorage(objDAInterfaceRetrieval);
        	 objListRecommendation = objADBridgeRetrieval.RetriveRecommendation(objInnerRecommendation);
        	 objInnerRecommendation = objListRecommendation.get(0);
         }

         assertEquals(objOuterRecommendation.getRecommendationDescription(), objInnerRecommendation.getRecommendationDescription());

         /* Testing of Update function*/
         objInnerRecommendation.setRecommendationDescription("testing for unit testing updated");
         objInnerRecommendation.setRecommendationDate("2016 12 12 01:30:01");
         DataAccessInterface objDAInterfaceUpdate = new RecommendationAdapter();
         AbstractDataBridge objADBridgeUpdate = new DatabaseStorage(objDAInterfaceUpdate);
         lstResponse = objADBridgeUpdate.UpdateRecommendation(objInnerRecommendation);
         if(lstResponse.size() == 2)
         {
        	 /* Testing of fetching function*/
        	 objInnerRecommendation.setUserID(2L);
        	 objInnerRecommendation.setRequestType("ByUserOnly");
        	 DataAccessInterface objDAInterfaceRetrieval = new RecommendationAdapter();
             AbstractDataBridge objADBridgeRetrieval = new DatabaseStorage(objDAInterfaceRetrieval);
        	 objListRecommendation = objADBridgeRetrieval.RetriveRecommendation(objInnerRecommendation);
        	 objInnerRecommendation = objListRecommendation.get(0);
         }

         assertEquals(objInnerRecommendation.getRecommendationDescription(), "testing for unit testing updated");
	}

}


text:
Jupiter, Saturn will offer rare celestial treat just in time for Christmas
By Kevin Lavery | WKAR • Dec 18, 2020
Credit NASA HQ PHOTO / Flickr
Sky watchers will get a rare holiday gift this year.
On Monday evening, Jupiter and Saturn will appear to be nearly on top of each other as the two largest planets in our solar system reach their closest point to each other in nearly 800 years.
The "Great Conjunction," as astronomers call it, will coincide with the winter solstice.
Shannon Schmoll is director of the Abrams Planetarium at Michigan State University. She says if weather permits, you can see the event in the southwest from now through Monday.
"All you need to do is go outside and look in the southwest right after sunset and you'll be able to watch Jupiter and Saturn over the course of the next several days pass each other. So, don't just go out on Monday. Try to go out as much as you can as long as it's clear."
The "Great Conjunction" will peak on Monday evening.
"The only thing that will be brighter than Jupiter will be the moon. So, look for the brightest thing in the sky as the sun is setting and that will be Jupiter, and then Saturn will be just to the upper left of it now and it will move to the lower right as we pass the conjunction," said Schmoll.
Jupiter and Saturn form a conjunction about every 20 years when their orbits appear to align in the sky.
Schmoll says some astronomers speculate it may have been a conjunction of Jupiter and Saturn, or possibly Jupiter and Venus that formed the storied "Star of Bethlehem" that heralded the birth of Jesus.
[For more Michigan news right on your phone, subscribe to the Stateside podcast on Apple Podcasts or Google Podcasts today]
Want to support reporting like this? Consider making a gift to Michigan Radio today.
Discovery of possible dwarf planet could lead astronomers to Planet Nine
By Ryan Grimes • Nov 18, 2016
flickr user Eurpoean Southern Observatory / http://j.mp/1SPGCl0
Our conversation with David Gerdes. He's a professor of Astronomy at the University of Michigan.
We're learning a lot about our tiny corner of the cosmos these days. That's thanks to improving technology and the increasing number of probes we're sending into the solar system.
But as much as we learned so far, there's still a lot about space that we don't know.
Recently, researchers have been trying to track down a theoretical Planet Nine. (That's the title formerly held by Pluto. Sorry, Pluto.)
University of Michigan astronomers recently came across a planetary surprise that might get us closer to that discovery. And it turns out Pluto might have a friend out there after all.
VIDEO: 2 U.S. Astronauts Venture Out For 1st All-Female Spacewalk
By Scott Neuman & Bill Chappell • Oct 18, 2019
How NASA's mission to "touch the sun" could make us safer on Earth
By Stateside Staff • Nov 6, 2018
NASA/Johns Hopkins APL/Steve Gribben
Stateside's conversation with Justin Kasper
On August 12, 2018, NASA's Parker Solar Probe launched into space on a mission to unveil some of the greatest mysteries surrounding our sun.
The probe features a 10 square meter heat shield made from carbon foam that can withstand up to 3,000 degrees without incinerating. The front of the probe is covered in a synthetic sapphire crystal that reflects around six megawatts of sunlight; enough energy to power a small village.
Justin Kasper is a lead investigator on the project. He joined Stateside at our recent Ann Arbor live show to talk about what he hopes to learn from the information collected by the probe.
Move over "Rocket Man" – Lake Orion astronaut records original music video in space
By Stateside Staff • Nov 12, 2018
Stateside's conversation with astronaut Andrew Feustel
Since being selected as an astronaut by NASA in 2000, Lake Orion native Andrew Feustel has been on three space missions and spent more than 61 hours on space walks outside the shuttle.
While floating 250 miles above the Earth earlier this year, Feustel added something new to his space resume: singer-songwriter. He recorded a music video for "All Around the World," a song written by his friend Gord Sinclair.


Mr. Li Huayue has been Deputy General Manager in Yanbian Shixian Bailu Papermaking Co., Ltd. since December 30, 2012. He used to be Head-Sales in the Company, as well as General Manager in another Yanbian-based paper sales company.
Mr. Xu Zhiqiang is Deputy General Manager Yanbian Shixian Bailu Papermaking Co., Ltd. He used to be Assistant General Manager in the Company and another Yanbian-based papermaking company.
Mr. Jin Changshou has been Chief Engineer in Yanbian Shixian Bailu Papermaking Co., Ltd. since June 16, 2008. He was Deputy Head-Production Management in the Company.
Ms. Dong Xiaofeng has been Director in Yanbian Shixian Bailu Papermaking Co., Ltd. since April 22, 2008. She is also Deputy General Manager of Changchun Office in China Orient Asset Management Corporation.
Ms. Liu Liying has been Director in Yanbian Shixian Bailu Papermaking Co., Ltd. since May 18, 2010. She is also serving as Business Manager in Changchun Office of China Huarong Asset Management Corporation.