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About HINRI Labs | Tracking Our Progress | Ignacio's Journey | Research
Transcutaneous Electrical Stimulation - Published Studies
HINRI Labs was created in 2018 with a mission to change the standard of care for chronic, complete spinal cord injuries. Our goal is to work with our clinical, military, and university partners to identify and accelerate the most promising treatments, technologies and protocols that have successfully demonstrated neurological recovery of movement, function, and/or sensation. We want to then make those breakthroughs accessible to patients, prove their effectiveness, and change the standard of care.
As you can read about below, we spent months literally traveling across the United States to visit the top research centers, leading laboratories and best rehab hospitals. We talked to as many experts as possible, both here in the US and across the world.
Based on our research, we feel confident that transcutaneous electrical stimulation offers the best opportunity to move us toward our goal.
We are partnering with Dr. Reggie Edgerton, the Director of UCLA's Edgerton Lab, also known as the "father of neuromodulation." Dr. Edgerton worked with the late Christopher Reeve after his spinal cord injury. Dr. Edgerton has been in the field for 53 years and is on the Scientific Advisory Board of the Christopher and Dana Reeve Foundation. He has been a leader in transcutaneous electrical stimulation. Here is a link to a few of his published studies. Dr. Edgerton and his colleagues performed the first implant of spinal epidural stimulation in human subjects with complete paralysis on Dec 7, 2009. This led to testing noninvasive means of stimulating the spinal circuitry.
Dr. Edgerton has found that the most logical interpretation of his research is that there are networks above, within, and below the lesion in a significant number of individuals diagnosed with complete, chronic paralysis that can be transformed into a functional connectome by receiving a specific critical type and level of spinal modulation that enables these networks to be re-engaged.
Reasons we are excited about this opportunity:
Demonstrated success with chronic, complete patients
Non-invasive (epidural electrical stimulation is another option, but it requires surgical implants and has not produced better outcomes)
Possible recovery of function and sensation
Long-term results vs losing function after the trial or rehab are over
Focused on the whole-person / multiple targets (stepping, walking, arms (including plexus), fingers, trunk, blood pressure, bowel/bladder/sexual function, etc.)
Collaborative - Dr. Edgerton wants to work with the VA and is willing to help create a center in Atlanta
The image above is a conceptual design of how paraplegics move from a wheelchair to over-ground stepping. (Note these are simplified schematic for the sake of representation.) A) Wheelchair-bound patient with no voluntary control. B) Oscillation in a gravity-neutral environment. C) Dynamic standing with posture control. D) Over-ground weight-bearing stepping aided by exoskeleton or body weight supported treadmill. E) Over-ground stepping aided by rolling walker device with sufficient safety straps (not shown).
Here are some links to videos demonstrating some of Dr. Edgerton's results:
https://www.youtube.com/watch?v=B78AZsa28f0
https://www.youtube.com/watch?v=tPej2l6dVbw&t=8s
https://www.youtube.com/watch?v=LTUvWhmBMOU
Currently in the US, after a complete spinal cord injury, patients are typically rushed home within a few weeks with a binder of instructions on how to live the rest of their lives paralyzed, in a wheelchair, in pain, fighting off infections, dealing with secondary complications, and with a substandard quality of life and life expectancy. They're told their injury is too severe or "complete," meaning that there's no sensation, movement, or function below the break, and that because of this diagnosis they do not qualify for any treatment intervention or rehabilitation. They are also told that any potential recovery that could possibly occur once the spinal swelling has gone down would typically happen spontaneously during the first two years of the injury, but that anything beyond that is impossible. Even for those who have less severe incomplete injuries or those who do recover some function during those first two years rarely see significant, sustainable results. Insurance does not provide funding because recovery has never been thought possible – until now.
To explore and evaluate these solutions from various angles, Ignacio Montoya MS BME, began a comprehensive effort to travel across the country visiting the leading laboratories and rehab hospitals and talk to as many experts as possible.
After having sustained a spinal cord injury himself in December 2012, Ignacio focuses on neurorecovery on a daily basis and is committed to transforming lives and changing the standard of care for all spinal cord injuries. Ignacio recently graduated first in his class from Georgia Tech with a master's degree in biomedical engineering and has also had extensive experience in changing the standard of care for peripheral nerve injuries at the Mayo Clinic. Ignacio has tested and evaluated various protocols and medical interventions on himself.
As part of our research, Ignacio, who is categorized as a chronic, complete (ASIA A) T-4 SCI, has developed protocols for intensive, activity-based rehabilitation. He has completed what he calls the 3/3/3 pre-intervention program – walking 3 hours a day, 3 days a week, for a total of 3 months on a robotic-assisted orthosis suspended over a treadmill, known as the Lokomat. In fact, in just over a year Ignacio has walked over 650 miles on the Lokomat, the most ever walked by anyone with paralysis.
We spent several months talking to the leading experts in the field of translational spinal cord injury research and asking each and every one of them the simple question: "How can we best accelerate your clinical work?" We visited and met with the following experts and institutions in an effort to refine our strategy and develop partnerships:
Department of Defense Spinal Cord Injury Research Program
Shepherd Center
Dr. Allan Levey, Chair, Department of Neurology, Emory University / Dr. Scott Boden, Director, Emory Orthopaedics & Spine Center
Bill Barrable, CEO of the Praxis Spinal Cord Institute (formerly the Rick Hansen Institute)
Dr. Reggie Edgerton, Department of Neurosurgery / Brain Research Institute, UCLA
Dr. Gregoire Courtine, Center for Neuroprosthetic and Brain Mind Institute of the Life Science School at the Swiss Federal Institute of Technology Lausanne (EPFL)
Dr. Wise Young, Founding Director, W. M. Keck Center For Collaborative Neuroscience, Richard H. Shindell Chair In Neuroscience, Rutgers University
Dr. Christine Sang, Director, Translational Pain Research, Brigham and Women's Hospital, Harvard Medical School
Dr. Graham Creasey, Paralyzed Veterans of America Professor of Spinal Cord Injury Medicine at Stanford University Medical School and former Chief of the Spinal Cord Injury Service at the Veterans Administration Palo Alto Health Care System
Hunter Peckham, Executive Director, Institute for Functional Restoration at Case Western Reserve University
In addition, Ignacio visited with, spoke to, or participated in the following research programs:
One week in Fort Worth, Texas at the Neurological Recovery Center, where he met, shadowed, and implemented his own neurorecovery protocols using the new Lokomat FreeD with the staff MD, Dr. Brian Wood.
One week in Birmingham, Alabama at the Lakeshore Foundation where Paralympic athletes train to participate in a study evaluating the effects of meditation, mindfulness, exercise, and nutrition after a spinal cord injury.
One week in Louisville, Kentucky at the Frazier Rehab Center & Kentucky Spinal Cord Injury Research Center, where he participated in a week of screening and evaluation of his candidacy for an implanted electrical stimulator designed to excite and prime the spinal cord to relearn human locomotion. On this trip and several times since, he has spoken with Dr. Susan Harkema, president of the Christopher and Dana Reeve NeuroRecovery Network and the number one expert in the world on epidural electrical stimulation, to evaluate her research.
One week in Miami, FL at the Miami Project to Cure Paralysis, where he toured their new multi-million dollar rehabilitation facility opening later this year, which is next door to the Miami VA Medical Center. He met with their president and founder, Marc Buoniconti, and Scientific Director, Dalton Dietrich, to discuss their groundbreaking work on Schwann and stem cell therapy, as well as their work in collaboration with Dr. Reggie Edgerton in the area of transcutaneous electrical stimulation. They are very excited and looking forward to partnering with us.
Three days in Toronto, Canada at the Rick Hansen Institute (now called Praxis Spinal Cord Institute) Researchers Meeting, where he discussed the North American SCI consortium initiative and the upcoming goals for their new research program. He plans to visit their Vancouver headquarters in September and has been asked by their leadership to join their board.
One week in Chicago, IL at the Shirley Ryan AbilityLab (formerly the Rehabilitation Institute of Chicago) where he met with Dr. Monica Perez and Dr. Francisco Benavides to test their transcutaneous electrical stimulation therapy on himself and tour their 1.2 million square foot facility that houses six human locomotion labs.
Ignacio returned to the Shirley Ryan AbilityLab in October of 2019 for seven weeks to participate in a clinical trial testing the effects of transcutaneous electrical stimulation on the spinal cord. After just 11 sessions he was able to voluntarily move his legs for the first time since his injury six years ago. (Here is a link to the video.)
Once we chose Dr. Edgerton's clinical trial as our best option, we were pleased to learn that Mary Kate Wold, the mother of one of our clinical trial patients (Peter), had utilized her extensive network and had come to the same conclusion. You can view a letter she wrote to the NIH here.
Our goal is to accelerate this and other technologies that help complete SCI patients regain their independence and change the standard of care so all patients have access to these breakthroughs. We will report our progress regularly on this website. Please follow our progress and help us spread the word!
Click here to return to the HINRI Labs home page.


The East Central PA Task Force (ECPTF) is a cooperative effort of Berks, Columbia, Luzerne, Montour, Northumberland, Schuylkill, and Wyoming counties. The task force is organized to assist member agencies with tools, strategies and guidance in their efforts toward an all hazards approach to emergency preparedness. This project, the ECPTF Special Needs Survey, is an example of these efforts. For the purpose of this project, a special needs individual is someone who is pre-identified as likely to require assistance in excess of that provided to the general public in a time of disaster, particularly in the event that large scale evacuation is necessary. These special needs could include, but are not limited to, requiring specialized medical equipment, difficulty walking, blindness, deafness, or being bedridden. They could also include having no easy access to transportation, not understanding directions public safety officials will provide due to language barriers, and not being able to receive those directions due to not having access to a television or radio.
The information entered in this database will be used by emergency responders to better identify and assist those individuals in our community who may be least able to help themselves in times of disaster. The information will be held securely and only accessed for the purpose of emergency response and planning. This service is government provided and completely free of charge. At the completion of the survey you will be asked if you would like someone from your local American Red Cross chapter to contact you to discuss personal and family emergency planning. This is an important opportunity as the first line of defense against the effects of disaster is personal preparedness. The American Red Cross will provide this service at absolutely no cost to you. However, if you answer no, we assure you that you will not be contacted. Your response to this question will in no way impact the efforts that public safety organizations will make to assist you if disaster strikes.


Itch (Latin: pruritus) is a sensation that causes the desire or reflex to scratch. Itch has resisted many attempts to classify it as any one type of sensory experience. Modern science has shown that itch has many similarities to pain, and while both are unpleasant sensory experiences, their behavioral response patterns are different. Pain creates a withdrawal reflex while itch leads to a scratch reflex.
The most common causes of itching of skin are contact dermatitis, allergy, and itching of unknown cause. Other possible causes, such as scabies, are more rare.
Within all the people who go to their doctor with itching of skin, 86% report having skin rash, 50% report having abnormal appearing skin, and 26% report having skin lesion.
Patients with itching of skin often receive complete physical skin exam performed (ml), excision, hemoglobin a1c measurement, biopsy, excision of skin lesion, other diagnostic procedures on skin and subcutaneous tissue, diagnostic procedures on ear and other gastrointestinal diagnostic procedures .
The most commonly prescribed drugs for patients with itching of skin include diphenhydramine (benadryl), hydroxyzine, hydrocortisone topical, triamcinolone, triamcinolone topical product, permethrin topical, clobetasol topical, betamethasone topical product, ketoconazole, betamethasone-clotrimazole topical, fluocinonide topical, desonide topical and doxepin .
Groups of people at highest risk for itching of skin include race/ethnicity = other.


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Q: Bluetooth subsystem in linux and BlueZ I'm trying to figure out how the BlueZ userspace library interacts with the Bluetooth subsystem in linux. Specifically, does anyone know answers to the following questions:

*

*The Bluetooth subsystem version in kernel 4.9 is 2.22. Does there exist a changelog specific for the Bluetooth subsystem?

*Do there exist requirements for a minimum version of the Bluetooth subsystem for a given version of the BlueZ library? E.g. what is the mininum version of the Bluetooth subystem for the latest BlueZ library (v5.43)?

NOTE: The main reason I'm asking is my interest in "experimetnal" BLE features and stuff that has been happening in BlueZ since the 5 release. I've already watched this excellent talk: https://www.youtube.com/watch?v=tclS9arLFzk and tried to grasp what sparse information is available from the bluez.org website.

A: Essentially the answer to my own question is this document:
https://git.kernel.org/cgit/bluetooth/bluez.git/tree/doc/mgmt-api.txt
I had a very helpful chat on the #bluez freenode channel which is possibly a more proper place for these kinds of questions.
Version 5 and up of bluetoothd (i.e. BlueZ userspace part) should work against any kernel version 3.4 and upwards. However there are some features that are missing unless you use a more recent kernel. Those features are listed in the document linked above.

A: In the link I posted below it is said that BlueZ utiles interact with kernel with berkley socket interface. It means that BlueZ utiles uses socket systemcalls to interact with kernel. There is also information that

BlueZ is the official Linux Bluetooth stack

So linux bluetooth subsystem is BlueZ itself.
About LE compability you may find this useful.
Here you can find useful information about BlueZ.

redpajama_set_name: RedPajamaStackExchange


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The all-inclusive partnership agreement will combine the MLB brand with MGM Resorts and playMGM brands across league and team sponsorships, data usage in gaming, promotion across MLB-owned media platforms, and domestic and international activations at MLB events.
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It's also available from satellite providers DirecTV and Dish Network .
The federal government will pay security costs, as it does for all U.S.
However, WrestleMania will still stream live on Sunday, April 5 at 7 pm ET on WWE Network and be available on pay-per-view.
Washington Football Team NFL $3B 16.
So if they're talking about a movie or a product, there is the initial engagement, but then it's the two and a half minutes of the weird, nonsensical spin-off of whatever that product led them to.
and Little League International.
The 2018 PFL season features the 126 fights in seven regular-season competitions, a bracket-style win or go home playoff and a $10 million post-season prize pool.
SiriusXM's subscribers had access to live play-by-play of all 13 opening day games as part of its regular season and Stanley Cup playoff schedule.
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These college-branded avatars are a great example of using digital technology to enhance and build fan engagement .
Elsewhere in the Caribbean, impacts were dealt to the Leeward Islands, the Virgin Islands and Puerto Rico.
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redpajama_set_name: RedPajamaCommonCrawl


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Ginga Sengoku Gunyuuden Rai is a Strategy game, published by Angel (Bandai), which was released in Japan in 1996.
We are still searching for cheats, codes, and hints for Ginga Sengoku Gunyuuden Rai (Super Nintendo). We do not have any cheats, codes, or hints yet.


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Group transforming former 'colored' fairground to park
The Reedy Fork/Rocky Creek Fairground Community Park is raising money to renovate the former home of the Greenville County Colored Fair.
Group transforming former 'colored' fairground to park The Reedy Fork/Rocky Creek Fairground Community Park is raising money to renovate the former home of the Greenville County Colored Fair. Check out this story on greenvilleonline.com: http://grnol.co/1BoawXg
Angelia L. Davis, davisal@greenvilleonline.com Published 5:46 p.m. ET Feb. 24, 2015 | Updated 5:56 p.m. ET Feb. 24, 2015
Robert Sweeney and other committee members are selling engraved bricks to raise money for amenities at the planned Reedy Fork/Rocky Creek Fairground Community Park.(Photo: Angelia Davis / Staff)Buy Photo
The site at 931 S. Garrison Road in Simpsonville has the makings of a playground and park. It has bleachers, a pavilion, a swing and a dirt track.
There was a time when it had so much more.
When blacks could only work at larger fairs in Greenville, they could actually experience a fair here when the 13-acre site was the Greenville Colored Fairground.
Once a year, there were carnival rides, concession stands, exhibits, and other activities that attracted blacks and whites from near and far.
The fair, said Robert Sweeney, a retiree who still lives adjacent to the site, "was my pride and joy. When I grew up, for the first 18 years, this is what I knew.
"It brought so much in my childhood that I want to spread it now," he said.
Sweeney is a member of a volunteer committee dedicated to bringing a carnival and other activity back to that property in the form of a recreational complex.
The Reedy Fork/Rocky Creek Fairground Community Park committee is raising money to erect restrooms, a concession stand, a tennis court, a basketball court, a volleyball court with sand, play areas, horseshoe pits, and lights.
"It's a work in progress," said Sweeney. "We're on a snail pace right now, but the turtle did win against the rabbit."
The property's journey from a fairground for "colored" people to a community park can be traced back to the 1920s.
That's when the Greenville County Colored Fair Association – a group consisting of black business men, professionals, and entrepreneurs in the city of Greenville was formed, according to information Sweeney compiled gathered from old Greenville News articles and association meeting minutes.
They held their first fair on Anderson Road in the city. Blacks brought canned goods, needle works, and farm products from their gardens and their livestock to show-off for prizes.
More than 14,500 people attended the second fair, held in a baseball park off Pendleton Street.
Its success was so great that it became difficult to find a place to host the event. It was held in different places until 1925, when they purchased the site now off Garrison Road for $10.
Here, the fair annually featured probably four rides for kids and seven adult rides, including small roller coasters, bump cars, a ferris wheel, brought in by carnival owners.
There was a hit-the-bell game, popcorn and candy apples. A concession stand lined the roadway on the property. People rented space there to sell such edibles as hot dogs, fish sandwiches, pigs feet, chitterlings.
Farmers also brought their fruits and vegetables to display.
"They showed them. People made contact with people who had them to sell and mostly the city folks would want to buy them because it was the country folks growing them," Sweeney said.
An exhibit building was on the site, with a grandstand in front where attendees could watch high school football games being played there, horse races, mule races, and foot races. On the lower end of the property were barns for livestock and then there were chicken coops.
Going to the fair was "just like going up town to one of those fancy parks back then. It was a big thing," said John Sullivan, who grew up in the community.
Growing up near the fairground, John Evans could hear sounds of the fairground activity while picking cotton during the weekdays.
He'd go on there himself on the weekend if he earned enough money.
"It cost a quarter to get in and that was hard to come by," he said. "A lot of times, I didn't have 25 cents so I'd slip in."
The association changed its name to the Greenville County Progressive Fair Association in the 1960s, "due to the relaxation of racial tensions and changes in the Jim Crow laws," Sweeney's report said.
The fair was ended in 1967, when Sweeney was a senior year in high school.
Dr. Martin Luther King was shot and killed the following year in April and white carnival owners didn't want to come back to the site because they thought blacks would riot and "tear up" their equipment, Sweeney said.
When efforts to revive the fair were unsuccessful, the property was rented out to the community for various events. Then, it went unused and unmaintained for years.
Sweeney, whose father was a secretary of the association, said the property had many stockholders. And, according to the association's constitution, it could not be sold.
So, it was given to Rocky Creek Baptist and Reedy Fork Baptist churches to "do what you will," in 1990, Sweeney said.
The churches had planned to build Life Centers on the property, he said. In 2000, a committee of members from both churches was formed to "clear, renovate, and maintain the property," known today as the Reedy Fork/Rocky Creek Fairground Community Park.
John Sullivan, a committee member and son of a stockholder, said talk of a park was really generated by their enjoyment of car shows.
"That's what sort of woke the thing back up," he said. "We got a lot of guys interested in the car shows and we just needed a place."
The churches donated money for the equipment to clear it, said Earl Sweeney, also committee member and son of a stockholder.
By 2007, volunteers had cleared more than half of the property of trees, weeds, and dilapidated buildings.
Funds were donated to build the pavilion there as a way to generate funds. Amenities now include a horseshoe pit, a ball field and shade tree areas.
The committee is selling engraved bricks to build restrooms and concession stands. Their goal is to sell at least 200 bricks, which will placed in a prayer garden in the park.
"We've got a long way to go, a tough road ahead, because we're going on donations mostly," Robert Sweeney said.
For information on donations to the park or to purchase a brick, contact Alice Burton @ 864-787-9216 or Robert Sweeney @ 864-293-1681.
More information is also available at http://www.rcmbc1895.org/fairground.php
Read or Share this story: http://grnol.co/1BoawXg
New Greenville restaurant offers opportunity for sex-trafficking victims
Clemson University begins planning for new student housing
Neighbors protest more homes, more traffic, a broken pool and missing soccer field
Clemson student Bryn Turner, 22, dies in Jacksonville Beach accident
3-year-old boy dead after falling into grease trap at Tim Hortons on University Avenue
Greenville man receives 15 years for trafficking fentanyl, other offenses


Gillette has launched a major promotion designed to help it drive a 20% jump in sales of key male grooming products.
Gillette has launched a major promotion designed to help it drive a 20% jump in sales of key male grooming products. The Mach3Turbo Champion promotion, which kicks off in mid-August, offers anyone purchasing a Champion system, Mach3Turbo blades or Gillette Series Shaving Gel the chance to win a 2006 Mercedes SLK 200 car. The two month promotion will initially run in the GCC countries, where it will be supported by a multi-channel advertising campaign worth at least US $1 million. Later in the year, a similar programme run in the Levant and Egypt. "For retailers, it's going to significantly increase footfall in the category," Mohamed Kashahy, associate business manager, blades & razors, Gillette Middle East & Africa, told Retail News Middle East. "Major innovations only come along every one or two years in the male grooming market, so they need promotions like this to help maintain the business." Mach3Turbo Champion is an extension of the Mach3Turbo system line, designed to appeal to a younger male demographic. The product comes in a bright red colour and uses images of cars, particularly Formula One vehicles, in its promotional material, hence the decision to offer a Mercedes SLK as a prize. With the forthcoming campaign, Gillette aims primarily to boost awareness of its grooming products amongst young males, particularly those coming into the shaving market for the first time. However, the promotion also forms part of the company's wider strategy to migrate users of disposable razors to more profitable systems products like Mach3 and Mach3Turbo. To help ensure 'Champion' is a success, it will be supported with a "fully-fledged" media campaign using TV, radio, outdoor and print. In-store material will be created for retailers. The last major Gillette male grooming campaign, 'Bend it With Beckham' achieved noteworthy results. Sales were around 20% above normal levels for the period of the promotion and Kashahy aims to achieve a similar result this time. The retention rate (the number of people buying an eligible product who then took part in the competition) was around 7%. The global average is normally around 4%, according to Gillette. To take part in the promotion, consumers SMS a code found on the product packaging to a special competition phone number. Every person taking part will receive either a picture message or ringtone. The draw to select the winner of the SLK will take place at the end of October.


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Brain cell reprogramming therapy shows promise for Parkinson's
By Supplier on	 April 12, 2017 Industry Articles
"New technique in which brain cells are reprogrammed could one day provide a cure for Parkinson's disease," The Independent reports.
Researchers, using mice with Parkinson's disease, "reprogrammed" cells to replace the nerves lost in the condition. These nerves produce the messenger chemical dopamine, and help to coordinate body movements.
Parkinson's is a neurological condition, of unknown cause, where there is a progressive loss of dopamine-producing nerve cells in the brain. The gradual loss of these nerves leads to the symptoms of Parkinson's, such as tremor and muscle stiffness.
In this study researchers used an injection of a specially engineered virus to introduce a combination of genes into the brains of the mice. These genes were designed to target a type of cell known as astrocytes. These cells serve a wide range of functions, but crucially they do not carry electrical signals like nerve cells or produce dopamine.
This virus was also able to convert astrocytes within the brains of the mice into dopamine-producing cells (which the researchers called induced dopamine neurons (iDANs)). They saw improvement in some aspects of walking in these mice when they exercised on a treadmill.
Researchers hope their methods could eventually be used to treat humans with Parkinson's.
While these are promising findings, it may be premature to call this a breakthrough, as BBC News put it. As yet, we do not know whether this approach could be used to reverse symptoms in people with Parkinson's disease.
The effectiveness, and more importantly the safety of this approach in humans is currently uncertain.
Where did the story come from?
The study was carried out by researchers from the Karolinska Institutet, Medical University of Vienna, Malaga University and Stanford University. Funding was provided by a large number of institutions, including the Swedish Research Council, Swedish Foundation for Strategic Research and the Karolinska Institutet. There were no reported conflicts of interest.
The study was published in the peer-reviewed journal Nature Biotechnology.
The UK media's reporting of the study, aside from a slightly over-optimistic tone, was accurate and included useful commentary from independent experts.
What kind of research was this?
This was a laboratory experiment and animal study in mice and human brain cells. It aimed to investigate whether it is possible to modify cells commonly found in the brain (called glial cells – specifically a type called astrocytes) to replace those lost through Parkinson's disease. The researchers hope this approach could reduce or reverse symptoms.
The nerve cells lost in Parkinson's disease are in a part of the brain called the substantia nigra. They produce a chemical called dopamine, which transmits signals from these cells to other nerve cells. Dopamine belongs to the class of chemicals known as neurotransmitters.
Researchers have been studying different ways to replace these cells. In the past they have been able to convert adult mouse and human skin cells into dopamine-producing nerve cells in the laboratory.
However, these cells would need to be transplanted into the brain, a procedure which could pose a number of serious risks.
In the current study, researchers wanted to assess whether they could get cells already in the brain to convert into dopamine producing nerve cells, to avoid the need for transplantation.
Animal studies such as this are a useful way to carry out early stage research which can then be refined before testing in human trials. In this case human cells were also modified in the laboratory, which increases confidence that the technique might work in humans.
What did the research involve?
The researchers used genetic engineering to get the glial cells to switch on genes needed to become dopamine producing nerve cells. Researchers tested the effect of switching on a number of genes in human glial cells in the laboratory under a number of different conditions. They aimed to identify the combination that was most effective at getting the glial cells to become dopamine producing nerve cells.
Mice were engineered to have symptoms of Parkinson's by destroying their dopamine-producing nerve cells. Their brains were then injected with the combination of genes, contained within a virus, which had been identified in the first set of experiments, to see if this would convert their glial cells.
They were then analysed five weeks later to see if this modification had resulted in improvements to their motor (movement) skills.
What were the basic results?
The researchers found that they were able to get human glial cells in the laboratory to convert into dopamine producing nerve cells. They got the best results when they used a specific combination of four genes important in the development of these cells. They could get up to 16% of the glial cells to develop the characteristics of dopamine-producing nerve cells.
They then injected this specific combination of four genes into the brains of some mice with Parkinson's-like symptoms. After five weeks, the treated mice appeared to walk better on a treadmill compared to control mice.
How did the researchers interpret the results?
The researchers conclude their findings show that in mice it was possible to re-programme cells in the brain to replace the dopamine-producing nerve cells lost in Parkinson's disease. As a result of this they were able to reverse some of the symptoms of Parkinson's in a mouse model of the disease.
The researchers conclude: "The next steps to be taken toward achieving this goal include improving reprogramming efficiency, demonstrating the approach on human adult striatal astrocytes … in vivo [in an actual human, as opposed to a lab experiment], and ensuring safety and efficacy in humans."
This laboratory and animal study aimed to see whether it is possible to modify a type of cell commonly found in the brain, called glial cells, to become dopamine-producing nerve cells. These dopamine-producing nerve cells are the ones lost in people with Parkinson's disease. If a method could be found to replace these cells, it could potentially be used to treat the condition.
Previous research has shown that mouse and human skin cells can be converted to dopamine-producing cells in the laboratory. However, this is the first study to develop a way to convert a different type of cell already in the brain into dopamine-producing nerve cells. It has also shown that this can produce improvements in Parkinson's-like symptoms in a mouse model of the disease.
These findings are promising, particularly as the researchers have shown that it is possible to use this technique to modify human cells as well as mouse cells. However, the approach has not yet been tested in people with Parkinson's and it is not possible to know whether the cells would function as expected or whether the change would be long lasting.
Even before human studies can be carried out, it is likely that more animal experiments would be needed to ensure the approach is effective and safe in the long-term.
Analysis by Bazian. Edited by NHS Choices. Follow NHS Choices on Twitter. Join the Healthy Evidence forum.
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Children's Brush Assortments offer a fantastic selection of kid-sized brushes at a great, economical price. These assortments include foam brushes, foam dabbers, chubby brushes, and artist brushes in a variety of shapes, sizes, and fun, bright colors.
This assortment contains 10 foam brushes, 10 foam dabbers, 15 chubby bristle brushes, 30 nylon watercolor brushes, 15 Camel Hair brushes, and 20 synthetic Flat Angle brushes for a total of 100 brushes.


Everyone has their good days and their bad days. In that regard, Sweet Girl is definitely within the norm. The only difference is that she seems to swing a little higher and a little lower, but she's always had a flair for the dramatic so that's not surprising. So after a really good couple of days some not-so-good days have followed. Sinuses flared, her nose bled, and crankiness ensued. And to exacerbate the situation we had to get her new shoes.
New shoes may not seem like cause for concern but the process of shoe-shopping is anxiety-ridden for Sweet Girl. If her feet would stay the same size and that size wasn't hard to find, I'd buy her shoes at Target while she was hanging with her dad. Alas, she has a wide foot (you're welcome Sweet Girl) and she keeps growing up despite my wish that she stay my little girl forever. Then there's the issue of the stench. Any sandal of Sweet Girl's is going to have a rather adventurous life. It will meet mud puddles, dirt piles, probably some Oreo offerings, and will take enough steps to wear out the tread on most Goodyears. This particular pair of sandals was well loved and therefore well worn, and oh they had the smell to prove it. We could smell Sweet Girl's shoes before we could see them. I was worried disposing of them would require cooperation from HAZMAT. It was definitely time for new sandals. To Stride Rite we go!
What Sweet Girl doesn't like about the shoe-shopping experience isn't the actual new shoes (though she used to limp around the house like her feet were asleep when introduced to new shoes - not any more much to my [somewhat inappropriate] disappointment), it's the measuring. A stranger is about to get in her space, touch her, and bodily move her parts. Not cool. And on this particular trip, to the one Stride Rite currently open in middle Tennessee, the store was busting at the seams with kids, strollers, parents, and grandparents grabbing shoes tax free and buy one get one half off. Sensory overload to say the least. Sean and Little Man scan our options while I gave Sweet Girl a pep talk; it's not going to hurt, it will only take a second, no one is going to hurt you, you don't have to be scared. She bravely sits on the bench but as the store employee comes over, the tears start to roll down her cheeks. I reiterate the pep talk adding the always popular "Mommy's right here. Don't worry." But she wants to be held and it's clear the employee is not digging the tax free madness and isn't willing to be creative. So Sweet Girl cries the whole time, all the while repeating "Don't cry. Don't cry. Don't cry sweetie." (clearly I say this more than I thought), and I feel terrible about shoes of all things.
It is, of course, over in about two minutes. Sweet Girl was not the only child crying or melting down in the store at that time. She gave me a "big ole hug" and a "Hurray! We did it!" when it was over. But I still feel terrible that I couldn't make her more comfortable and that we will have to buy shoes again someday. My sister-in-law, who feels my pain on this, and I will someday open a shoe store/hair salon/portrait studio for people with sensory issues. Low lighting, appointments can be made for individual attention, games, movies, wide open spaces, whatever it takes to make these necessary and important things easier for those who need a little time and space and especially for their parents who feel their stress and anxiety a million times over. But until that day (here's to a good walnut crop!) we keep working on it. Sweet Girl gets braver and my house smells better with the old sandals gone. She's a sweet girl but she has stinky feet.
Side note: When we got home (about 50 miles from the craziness) we realized that there were two right shoes in the box. Dad to the rescue! He and Little Man returned them the next day and got Sweet Girl a shoe for each foot. He's a good dad.
This made me cry, thinking about Annie crying and trying to calm herself down. Poor princess.


The 'Zeppelins' are our signature skinny jeans and a staple in all of our wardrobes. We've now got em' in a new cord colour, just for the change of season! These are a super skinny high-waisted fit, and are slightly cropped in length.


In this economic struggle people are forced to count every single penny they are spending and justify the cost. When hiring limousine services there isn't any exception to this leadership. But how do you choose which service decide on when there is this particular type of wide array of charges? For limousine services may vary from $50-$500. What determines this huge price gap? Truthfully, there are reasons behind it as well as shall break it down for you.
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Limousine service prices are vastly different, but if you determine your needs, the particular occasion, plan ahead and save for the service, then making the correct decision for you end up being easy resulting in an unforgettable experience for you and/or visitors.


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Write on the envelope "application for the post of Part Time Instructor (Art / Physical)".


text:
Donald Mainland FRSE FRSC (1902-1985) was a Scots-born medical statistician who became a Professor at the New York University. He is remembered for his series of Mainland's Notes.

Life
He was born in Edinburgh in 1902, the son of William Mainland, a confectioner running a shop at 140 St Stephen Street in the Stockbridge area.

He studied medicine at the University of Edinburgh graduating with an MB ChB and gaining a doctorate (DSc) in 1930. He was a lecturer in anatomy at the University of Edinburgh and was elected a Fellow of the Royal Society of Edinburgh in 1938. His proposers were Ernest Cruickshank, James Couper Brash, Alfred Joseph Clark and Ivan De Burgh Daly. In 1954 he was named a Fellow of the American Statistical Association. He resigned from the Royal Society of Edinburgh in 1965.

In 1949 he emigrated to Nova Scotia to take on the role of Professor of Anatomy at Dalhousie University. His personality clashed with his junior colleague, Dr Richard Holbourne Saunders (who then replaced him) and one year later he was appointed Professor of Biostatics in the Department of Preventative Medicine at the Bellevue Hospital Medical College in New York City in the United States. In 1953 he moved to the Department of Medical Statistics as its Chairman.

Publications
Mainland's Notes from a Laboratory of Medical Statistics
Mainland's Statistical Ward Rounds
Mainland's Notes on Biometry in Medical Research
Mainland's Elementary Medical Statistics''' (1952)Statistical Tables for Use in Binomial Samples''

References

1902 births
1985 deaths
Alumni of the University of Edinburgh
Academics of the University of Edinburgh
Scottish anatomists
Fellows of the Royal Society of Edinburgh
Fellows of the Royal Society of Canada
Fellows of the American Statistical Association
British emigrants to the United States

redpajama_set_name: RedPajamaWikipedia


text:
De HMAS Swan (D61) was een Australische torpedobootjager van de Riverklasse.

De Swan tijdens de Eerste Wereldoorlog
De Swan was aanwezig bij de invasie van de Duitse koloniën in Zuidoost-Azië. In 1917 werd het schip overgeplaatst Middellandse Zee in verband met de toegenomen dreiging van Duitse onderzeeboten in dat gebied.

De Swan na de Eerste Wereldoorlog
Na de Eerste Wereldoorlog keerde de Swan terug naar Australië waar het tot 1928 dienstdeed. Tussen 1922 en 1925 werd het schip in reserve gehouden. Vanaf 1925 is het schip alleen nog gebruikt als opleidingsschip. Na de uit dienst name is het schip in 1930 verschroot.

Zie ook
 HMAS Swan, voor andere schepen met de naam Swan

Swan (D61), HMAS
Swan (D61), HMAS
Swan (D61), HMS


Hiplife artiste, Kwaw Kese has launched a new attack on the self-acclaimed dancehall king, Shatta Wale.
According to the ' little things ' hit maker , she does not need a man because she can satisfy herself when she wants to.
DJ Switch is currently in America for Goalkeepers2018 and has met with the president of France, Emmanuel Jean-Michel Frédéric Macron.
Ibrah is still matching Nana Appiah Mensah boot for boot ever since Menzgold started having issues with SEC, forcing it to be shut down.
The controversial man of God demonstrated to his interviewer how his edited interview with Delay ensued.
According to him, he was depressed and needed time off for himself to get well before he could come out.
Bisa Kdei, a renowned contemporary Highlife artiste, has expressed worry about the degenerating nature of Ghana's Highlife.
Kwadwo Nkansah, known in the music and film industry as "Lil Win" would commission a new school building on Tuesday, September 25, 2018.
Rufftown Records signee , Wendy Shay has said that her only regret is not collaborating with Ebony Reigns when she was alive.


The single-sided, Style B teaser poster measures 27" x 40" and is in very good to excellent condition with minimal edge wear. It has never been folded.
Please look closely at the photo as this is theexact poster you are buying. It is not cropped or a stock image.The small, black circles in the corners of the poster are magnets and not pins.
This collectible poster, teasing the July 3, 1996 release of Independence Day, is not a reproduction or a reprint.


Need help getting here? No problem, just click this link here on your Smartphone to open up Google Maps. See you soon!
We are open every day Tuesday to Sunday from 4pm until 11pm! We are closed on Mondays (fishing for crabs!).
Mains - Build your bag!
Add sides to your bag!
Add flavour to your bag!
Add spice to your bag!
We serve a bring your own wine policy at The Fat Crab however please note that we charge a corkage fee of £5.00 per bottle brought into our restaurants.


Ridgecrest Seniors are legacy builders. Our senior adults are an active group and they are known for having a good time serving the Lord. From strong Sunday Bible Study groups to fellowships, fitness, and service, you can build a legacy of faith that will be passed from faith to faith.


text:
Q: SQL query into phpmyadmin - error in syntax I'm trying to create an email validation for user registration.
I am following step by step instructions but i am bogged down in something that should be quite simple.
I am supposed to insert the following into a database using a MySql query:
mysql_query("INSERT INTO users (username, password, email, hash) VALUES(
'". mysql_escape_string($name) ."',
'". mysql_escape_string(md5($password)) ."',
'". mysql_escape_string($email) ."',
'". mysql_escape_string($hash) ."') ") or die(mysql_error());

I am using WAMP server. I went to my database, selected the table, inserted the above after selecting the SQL tab, clicked go and got the response:

"#1064 - You have an error in your SQL syntax; check the manual that
  corresponds to your MySQL server version for the right syntax to use
  near 'mysql_query("INSERT INTO users (username, password, email, hash)
  VALUES( '". m' at line 1"

I can never seem to insert queries into the phpMyAdmin databases without getting some sort of error. I'm hoping someone can shed some light on this to give me an outside view.
Needless to say, i would be grateful for any input. I am new to this and at my wits end.

A: You can't use PHP functions in SQL. Run the PHP code instead

A: As Prash said, mysql_query and mysql_escape_string are php functions beside their names.
When pasting into the SQL tab of phpMyAdmin, you should remove the mysql_query() which represents PHP call to MySQL db and convert mysql_escape_string calls to the computed values of variables ($...). It should give you something like:
INSERT INTO users (username, password, email, hash) VALUES(
'SampleName',
md5('SamplePassword'),
'SampleEmail@example.com',
'SampleHash')

You need to escape by yourself if there are special chars in values)


text:
(Redirected from 12 July)
July 12 is the 193rd day (194th in leap years) of the year in the Gregorian Calendar, with 172 days remaining.
Template:JulyCalendar
2 Births
4 Holidays and observances
1573 - Spanish forces under the Duke of Alva capture Haarlem after a seven month siege.
1690 - William of Orange's army wins the Battle of the Boyne as reckoned under Gregorian calendar.
1759 - British cannon start firing on French at Quebec, from Lévis, Quebec.
1812 - Americans invade Canada at Windsor, Ontario.
1862 - Medal of Honor authorized by the US Congress.
1892 - A hidden lake bursts out of a glacier on the side of Mont Blanc, flooding the valley below and killing around 200 villagers and holidaymakers in Saint Gervais (http://fr.wikipedia.org/wiki/Saint-Gervais-les-Bains)
1932 - Lambeth Bridge, London, opened by King George V of the United Kingdom
1932 - Hedley Verity establishes a first-class record by taking all ten wickets for only ten runs against Nottinghamshire on a pitch affected by a storm.
1933 - Congress passes the first federal minimum wage law in the United States: 33 cents per hour.
1943 - The largest tank engagement ever takes place, part of the Battle of Kursk
1950 - René Pleven becomes Prime Minister of France
1960 - Orlyonok, the main Young Pioneer camp of the Russian SFSR, is founded
1967 - Four days of race riots begin in Newark, New Jersey that will claim the lives of 27 people.
1973 - The 1973 National Archives Fire destroys the entire 6th floor of the National Personnel Records Center
1975 - São Tomé and Príncipe declare independence
1979 - The island nation of Kiribati declares independence
1993 - A magnitude 7.8 earthquake off the shore of Hokkaido, Japan launches a devastating tsunami, killing 202 on the small island of Okushiri
1998 - KDE 1.0 released.
2002 - Gay rights: The Superior Court of Ontario orders Ontario to recognize same-sex marriages.
2004 - Pedro Santana Lopes is officially appointed Prime Minister of Portugal.
100 BC - Gaius Julius Caesar, Roman soldier and politician (d. 44 BC)
1394 - Ashikaga Yoshinori, Japanese shogun (d. 1441)
1468 - Juan del Encina, poet and composer
1714 - Christoph Willibald Gluck, German composer (d. 1787)
1730 - Josiah Wedgwood, English potter (d. 1795)
1807 - Thomas Hawksley, English civil engineer (d. 1893)
1817 - Henry David Thoreau, American writer and philosopher (d. 1862)
1819 - Charles Kingsley, English writer (d. 1875)
1824 - Eugène Boudin, French painter (d. 1898)
1849 - Sir William Osler, Canadian physician, author, professor of medicine (d. 1919)
1850 - Otto Schoetensack, German anthropologist (d. 1912)
1852 - Hipólito Yrigoyen, President of Argentina (d. 1933).
1854 - George Eastman, American inventor (d. 1932)
1855 - Edward 'Ned' Hanlan, rower (d. 1908)
1861 - George Washington Carver, American botanist (d. 1943)
1868 - Stefan George, German poet (d. 1933)
1870 - Louis II of Monaco (d. 1949)
1876 - Max Jacob, French poet (d. 1944)
1880 - Tod Browning, American film director (d. 1962)
1884 - Amedeo Modigliani, Italian painter and sculptor (d. 1920)
1886 - Jean Hersholt, Danish film director and actor (d. 1956)
1892 - Bruno Schulz, Polish writer and painter (d. 1942)
1892 - Harry Piel, actor, film director, and producer (d. 1963)
1895 - Kirstin Flagstad, Norwegian soprano (d. 1962)
1895 - R. Buckminster Fuller, American architect (d. 1983)
1895 - Oscar Hammerstein II, American lyricist (d. 1960)
1902 - Günther Anders, philosopher and writer (d. 1992)
1904 - Deng Xiaoping, Chinese politician and leader (d. 1997)
1904 - Pablo Neruda, Chilean poet, Nobel Prize recipient (d. 1973)
1908 - Milton Berle, American comedian (d. 2002)
1909 - Joe DeRita, American actor and comedian (d. 1993)
1917 - Andrew Wyeth, American artist
1920 - Beah Richards, American actress (d. 2000)
1920 - Pierre Berton, Canadian journalist and writer (d. 2004)
1922 - Mark Hatfield, U.S. Senator from Oregon
1925 - Roger B. Smith, American automobile executive
1930 - Gordon Pinsent, Canadian actor, director, and writer
1932 - Otis Davis, American runner
1933 - Donald E. Westlake, American author
1934 - Van Cliburn, American pianist
1937 - Bill Cosby, American comedian and actor
1937 - Lionel Jospin, Prime Minister of France
1943 - Christine McVie, singer, musician, and songwriter (Fleetwood Mac)
1947 - Gareth Edwards, Welsh rugby player
1948 - Richard Simmons, American fitness trainer
1948 - Nusrat Fateh Ali Khan, Sufi musician (d. 1997)
1964 - Gaby Roslin, English television presenter
1967 - Richard Herring, English comedian
1971 - Kristi Yamaguchi, American figure skater
1976 - Anna Friel, British actress
1977 - Brock Lesnar, American professional wrestler
1984 - Gareth Gates, British singer
1986 - Chris Ansette, British actor
1991 - Erik Per Sullivan, American actor
783 - Bertrada, wife of Pippin III (b. 720)
1441 - Ashikaga Yoshinori, Japanese shogun (b. 1394)
1536 - Erasmus, Dutch writer and philosopher
1845 - Henrik Wergeland, Norwegian author (b. 1808)
1918 - Dragutin Lerman, Croatian explorer (b. 1864)
1919 - Charles Rock, actor
1921 - Ralph Herz, actor
1923 - Harry Lonsdale, actor
1926 - Gertrude Bell, English archaeologist, writer, spy, and administrator (b. 1868)
1931 - Nathan Söderblom, Swedish clergyman, Nobel Peace Prize laureate (b. 1866)
1935 - Alfred Dreyfus, French military officer (b. 1859)
1949 - Douglas Hyde, first President of Ireland (b. 1860)
1950 - Elsie De Wolfe, actress and interior decorator (b. 1865)
1962 - Roger Wolfe Kahn, American band leader (b. 1907)
1988 - Josh Logan, film director and writer
1996 - John Chancellor, American television journalist (b. 1927)
1996 - Jonathan Melvoin, musician and keyboardist (The Smashing Pumpkins) (b. 1961)
1999 - Bill Owen, British actor (b. 1914)
2003 - Benny Carter, American musician (b. 1907)
Holidays and observances
Kiribati - Independence Day
Mongolia - Naadam Holiday (2nd day)
Northern Ireland - Battle of the Boyne Day (see Irish calendar).
São Tomé and Príncipe - Independence Day
Sunset and sunrise occur along Manhattan's street grid centerline
The "central pivot irrigation day" of Colorado
BBC: On This Day (http://news.bbc.co.uk/onthisday/hi/dates/stories/july/12)
July 11 - July 13 - June 12 - August 12 -- listing of all days
January | February | March | April | May | June | July | August | September | October | November | December
af:07-12 ar:12 يوليو ast:12 de xunetu bg:12 юли ca:12 de juliol cs:12. červenec cy:12 Gorffennaf da:12. juli de:12. Juli et:12. juuli el:12 Ιουλίου es:12 de julio eo:12-a de julio eu:Uztailaren 12 fr:12 juillet fy:12 july gl:12 de xullo ko:7월 12일 hr:12. srpnja io:12 di julio is:12. júlí it:12 luglio he:12 ביולי ku:12'ê tîrmehê lt:Liepos 12 lb:12. Juli hu:Július 12 nl:12 juli ja:7月12日 no:12. juli nb:12. juli nn:12. juli oc:12 de julhet pl:12 lipca pt:12 de Julho ro:12 iulie ru:12 июля sk:12. júl sl:12. julij sr:12. јул fi:12. heinäkuuta sv:12 juli tr:12 Temmuz uk:12 липня zh:7月12日
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Integrating superfoods into your day has never been so convenient and so craveable. Navitas Naturals Superfood+ snack mixes combine our most popular superfoods with nutrient rich seeds and nuts. Our organic Goji Basil Cashews are zesty 'handfuls of goodness' that feature our Goji Berries, raw cashews, organic spices and sea salt.
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These pizza-inspired superfood cashews are a unique and delicious blend of raw cashews, goji berries and basil. A touch of sea salt helps delivery this savory Italian flavor. Our 'handfuls of goodness' can be eaten straight out of the bag, but the possibilities don't stop there. You can add Goji Basil Cashews to trail mix, baked goods, granola and cereal, or sprinkle them on salads.


The abbreviation of the journal title "Correctional health care report" is "Correct. Health Care Rep.". It is the recommended abbreviation to be used for abstracting, indexing and referencing purposes and meets all criteria of the ISO 4 standard for abbreviating names of scientific journals.
Correctional Correct. matches the stem "correction-"


text:
Josef Šusta was a Czech aquaculturist and is considered to be among the modern "fathers" of the practice. He is notable for having written the 1884 book "On Nutrition of the Carp and its Fishpond Associates", as well as, alongside Antonin Fric and Josef Kafka, revitalizing the aquaculture industry in the Třeboň Basin by increasing pond productivity.

Works
 Výživa kapra a jeho družiny rybničné, 1884
 Fünf Jahrhunderte der Teichwirtschaft zu Wittingau (Pět století rybničního hospodářství v Třeboni), 1889
 Hospodářsko-rybářská těžba v rybnících (1868)

References

Further reading
 Tomeš, Josef: Český biografický slovník XX. století. V Praze: Paseka 3 volumes ,  OCLC 43599240 p. 326.
 Jiroušek, Bohumil: Josef Šusta, nestor českého rybníkářství. Historický obzor, 1998, 9 (1/2)
 Křivánek, Jiří; Němec, Jan; Kopp, Jan: Rybníky v České republice. Praha: Consult, 2012. 303 pp.  pp. 159–162
 Šusta, Josef [junior]: Léta dětství a jinošství. Vzpomínky I. Melantrich, Praha 1947, particularly the chapter Můj otec (pp. 53–76)

External links
Rybářství Třeboň Hld. a.s.: Josef Šusta
iDNES.cz: Třeboňský kapr slaví osmdesát let. Otcem byl rybníkář Josef Šusta, by Marek Podhora, 4 September 2019

Pisciculturists
People from Benešov District
1835 births
1914 deaths


text:
Savior of the World Production
Production Guidelines
Historical and Cultural Background
Music Callings
Basic Costuming
Every cast member had four basic costume pieces: a robe, a drape, a belt, and sandals. The majority of the cast also had an angel robe worn over their basic costume for chorus scenes in which they represent heavenly beings.
The basic robe was a modified T-shaped garment made from rustic materials. Some fabrics that worked well were monk's cloth, linen or linen looks, raw silks, textured cottons and rough woolen looks. Robes were worn about ankle length. Sleeve length was at or slightly above the wrist.
Drapes were made from lengths of fabric about 2 1/2 to 4 1/2 yards each. Fabrics used included rayon, upholstery (without backings), wool, linen, antique satins, and chiffons. Carl Bloch's paintings greatly influenced the design and use of drapes. The way a drape wraps around the body helps create the feeling of encumbrance in mortality. Therefore, actors and directors should pay special attention to the use of drapes and how they are worn.
Belts were made mostly from rope, fabric scraps and gimp (upholstery) trims. Many belts used combinations of these elements braided together.
Sandals resembled Jewish styles of the period. Some modern styles, such as thick soles, are not appropriate. Sources for the sandals were found through research on the Internet.
Beards and Head Coverings
If the men in the cast had time and it did not interfere with school or employment, they grew out their beards and hair. Head coverings were used to give variety to scenes and to cover short or blonde hair on both men and women.
Return to the Costuming main page.
Additional Costuming Notes
Depicting the Savior on Stage
Instructions for Creating Basic Costumes


Interested in Program in Integrated Arts? Save it to your profile for easy future access! Use the share option to let your friends and family know it's on your list!
Plymouth State University / Program in Integrated Arts is located in Plymouth, NH, in a small setting.


WONDERFUL XmasGIFT TO YOUR HONEY !!! GRACEFUL LEAD-TIN ALLOY PLATED ,TRUE LOVE SERIES CRYSTAL PENDANT NECKLACE .B129 | Jewels, Didn't you Know?Jewels, Didn't you Know?
This is all the color,Please leave a message you need color.


It's getting to be that time of year - as the mercury rises, so does the likelihood of major transactions. Come July, players will be trading uniforms like we do baseball cards as teams try to lock and re-load their rosters in order to boost their playoff chances. Every summer, we fans wait with bated breath to see where the big names end up and find out if our favorite teams did enough to reinforce their rosters for the grueling schedule to come.
Of course, I'm talking about the official opening of the free-agent period in the NHL. What - you thought I was referring to the MLB trade deadline? Oopsy, my bad.
Anyway, while Theo Epstein and crew figure out whether they need to acquire a reliable reliever, an offensive boost, or a starting pitcher more for the dog days of summer, Stan Bowman has already reportedly plugged a hole on the Blackhawks' roster. If Chris Johnston of Sportsnet is to be believe, Cam Ward will be bring his mask and pads to Chicago to serve as Corey Crawford's back-up for the 2018-19 season. The free-agent signing period doesn't actually open until July 1st, but it's believed that the one-year, $2.5 million contract is all but official.
The Hawks were a major disappointment last season, failing to make the playoffs for the first time in nine years. After nearly a decade of being the dominant force in the Chicago sports market, the current dynastic window appears to be nearly closed.
While all phases of the game can be blamed for their rapid decline, their performance between the pipes was a major contributor. Crawford's murky injury issues kept him off the ice for most of the campaign and his replacements simply could not fill his skates. Anton Forsberg, Colin Delia, JF Berube, Jeff Glass, and literal guy off of the street, Scott Foster, posted a combined .902 save percentage and a 17-30-8 record. This simply was not getting the job done and, with Crow's health still a big question mark, a reliable, veteran presence was needed in the net.
The longtime goalie of the Carolina Hurricanes is certainly no longer in his prime. Far removed from his days as a playoff MVP and Stanley Cup winner in 2006, the 34-year old has been in something of a platoon, splitting time with former Blackhawk, Scott Darling, last year. On the season, Ward contributed a 23-14-4 record with a 2.73 goals-against average and .906 save percentage in 43 games.
Here's hoping that, at the very least, Ward can provide a steady presence on the roster and find a way to lock the revolving door that led to the net in 2017-18. Ideally, a recovered Crawford will keep Ward from seeing too much time on the ice anyway.
Luckily for me, I had a pair of Cam cards stashed in my hockey trade box, which you can see above. I'll wait until July 1st to add him to my Blackhawks All-Time Roster Collection, just in case the deal falls through before the official signing period begins, but it sure looks as though these previous bits of trade bait came in handy. Perhaps I'll be able to mine that box for more cards once the free agents begin moving in earnest come Sunday? The Hawks sure could use a forward and a defenseman or two and Bowman and company actually have some cap space to work with - Ward's modest deal did not change that. We'll see what happens.
In the meantime, welcome to Chicago, Mr. Ward! Oh... and Theo... maybe you can bring in a rotation arm to eat some innings or a bench bat? That roster-shuffling period will be here before we know it.
I never liked Cam Ward-mostly because I was cheering hard for the Oilers in '06 and I cant stand the 'Canes franchise. But now that he's in Chicago that will change. Can't believe he's 34...where does the time go?


Club Penguin Cheats by Mimo777 Club Penguin Cheats by Mimo777: Club Penguin 2011 Island Adventure Party Cheats!
Here's something you might like. If you have Herbert's Revenge and you've given coins to your penguin, you get the unlocked items you got from the game! And if you're a non-member you can wear your crab costume (Misson 8) to the Hidden lake and play the game!I figured all this myself.
yeah this party is pretty good! I guess CP had to make up for all the glitches and ok parties. Its cool too because this is the most pins ever given out at a party!
I think it was last given out 2007 or 2008? Now everyone has it!
The "X" is not showing up for me. Anyone know why?
I wish club penguin would give free items to non members that are not hats. It's always pins, backgrounds or hats. :( But, AWESOME PARTY!
I have a normal crab costume I unlocked and it works as a blue crab costume too! Really cool! I'm not a member!
im so mad that they are pins and not items i need the eye patch!
I love all of this new pins!
Have you completed the Scavenger Hunt yet? You must collect the key pin in order to get the free hat item. Once you finish the hunt and have the key pin, you can go to the Cove to drill up the hat. The "X" should be there.
WITH THE BLUE CRAB COSUME IN THE HIDEN LAKE YOU CAN (NON MEMBERS TOO) CAN USE THE RED CRAB COSTUME TOO!
@Daisy If the "X" wont show up at your screen it is consider a BUG and just wait until CP fixes it and you will have your free Continental hat and finish the quest of the Missing Cream soda!!
Hey, me too! IWhen I logged in, I was so surprised! Lolz. It's probably a glitch.


The payback for you is a lot bigger than the €69 you pay us.
You have peace of mind knowing that you and your family are safe.
You will reduce your carbon footprint emissions.
You will save money because your boiler will be running more efficiently.
You prolong the life of your boiler.
Protect from more costly boiler repairs and breakdowns.
According to the SESI a boiler not serviced could cost you up to €150 extra per year. So gas boiler servicing will save you money.
On completion you will receive a RGI certificate and a digital printout on the performance of your boiler.
The payback for you is a lot bigger than the €99 you pay us.
According to the SESI a boiler not serviced could cost you up to €150 extra per year.
Typically around 80 % of a buildings energy usage is to heat the building and to provide hot water. Below are some tips to help reduce your energy usage and save money on your household bills.
1. Maximise your insulation Insulate the floor of your attic and access hatch. This is relatively cheap and easy. Increasing the insulation for the walls is more difficult for an existing building and the options which are available are: pumping insulation into the cavity (recommended option), externally applying insulation and then internally applying insulation.
2. Upgrade your heating controls Provide more effective control of your home heating by upgrading the heating controls in your home. Provide thermostats and a digital timer control so that the heating is automatically controlled once set. Install thermostatic controls to each radiator so that each radiator/room can be individually controlled also.
3. Service your boiler regularly. Regularly servicing your boiler will ensure it will run efficiently and prolong its life it can also reduce your gas bill by as much as 6%. However ensure that the person servicing the boiler is trained/gas boiler engineers have the correct equipment like a flue gas analysiser. When you need a boiler replacement you should purchase the most efficient one that your budget allows. In the case of oil and gas boilers always buy a condensing boiler and remember cheap boilers will cost you more in boiler repairs.
4. Use energy efficient lighting and turn off unnecessary lights. Use energy efficient light bulbs especially for outside lighting. These bulbs will typically use 20% of the energy of normal bulbs and last many times longer. However even when these bulbs are installed, switch off any lighting when not necessary.
5. Reduce the temperature of your home. Try and set your thermometer for a temperature of around 19 degrees, which should usually be sufficient, if this isn't, try and increase the temperature only in the most used room or try wearing more clothes. It has been estimated that for every 1 degree reduction in the temperature of your thermostat your heating bill will reduce by approx. 10%.
6. Draft proof your home. Seal the building to prevent excessive heat loss, but maintain air vents in working order. In the typical home 50% of heat loss is through drafts and open doors.
7. Use your electrical appliances efficiently. There are many ways to save electricity and money when using electrical appliances.
Stillorgan Gas & Plumbing Ltd.


text:
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Katee Schalau
Katee moved to Florida at three years old and was raised in Ponte Vedra Beach. She graduated from Nease High School and went on to the University of North Florida, earning a Bachelor of Science degree in Communication with a concentration in Public Relations. After graduating from UNF, she moved to the Midwest but longed to return to the sunshine state. In 2019, Katee returned to Florida with her son and settled in St. Augustine. She works from home fulltime in marketing for an electronics manufacturer based out of California. When she's not at home working or writing, Katee and her son are usually out and about, exploring and enjoying fresh air and sunshine. She is excited to be a part of the St. Augustine Moms team, combining three of her favorite things: being a mom, writing and St. Augustine.
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Hey all! My name is Katee Schalau. Yes, my first name is spelled like that on my birth certificate (my parents were ahead of their time on unique name spellings). And no, I've never...
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