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Eastern District of Virginia
G. Zachary Terwilliger
Contact: Joshua Stueve
www.justice.gov/usao-edva
Law Enforcement Executes Federal Gun and Drug Sting in Petersburg
RICHMOND, Va. – Over 150 law enforcement agents and officers executed a coordinated takedown this morning in Petersburg, arresting seven individuals on various drug and firearms charges including heroin, fentanyl, and cocaine distribution and possession of a firearm by a convicted felon. An eighth individual was arrested in Texas and a ninth individual was already in custody on state charges.
"This operation represents our commitment to public safety in Petersburg," said G. Zachary Terwilliger, U.S. Attorney for the Eastern District of Virginia. "Illegal firearms and drugs are often driving forces behind the violent crime that we are addressing in communities across the Eastern District. The actions taken today reflect the coordinated, skilled and brave work of law enforcement, and I want to thank the ATF and the Petersburg Bureau of Police for their partnership and commitment to reducing violent crime in Petersburg. These are serious allegations and each defendant is presumed to be innocent until and unless proven guilty in court."
"What we see today is the fruit of the strong partnership between ATF and the Petersburg Bureau of Police," said Ashan Benedict, Special Agent in Charge of the ATF's Washington Field Division. "Going forward, ATF will continue to stand alongside the City of Petersburg and stay committed to targeting those who commit violent crimes and illegally possess firearms."
"Today is a great day for our city," said Kenneth Miller, Chief of Petersburg Bureau of Police. "The Petersburg Bureau of Police is committed to keeping our streets safe and making the City of Petersburg a better place to live. I'm extremely appreciative of our strong relationship with the ATF and our federal partners, and I look forward to continuing to work together to target those who choose to break the law. Today's enforcement activity is a great example of our strategic approach going forward."
Below is a table which lists the name, age, hometown, and respective charge(s) each defendant faces.
Name, Age
Charge(s)
Armon Lee, 26
Sale or Disposal of a Firearm to a Convicted Felon; Distribution of Cocaine
Terrell Dean Johnson, 30
Distribution of Cocaine
Titus Maurice Lee, 44
Distribution of Cocaine; Distribution of Heroin and/or Fentanyl; Possession of a Firearm/Ammunition by a Convicted Felon; Sale or Disposal of a Firearm to a Convicted Felon
Autrelle Malik Waddell, 22
Distribution of Heroin and/or Fentanyl; Sale or Disposal of a Firearm to a Convicted Felon
Miles Owanga Johnson, 39
Distribution of Heroin and/or Fentanyl
Charles Lee Avery, 44
Possession of a Firearm/Ammunition by a Convicted Felon
Tyrell Jakahree Allen, 26
Vincent Edward Stewart, 29
Sale or Disposal of a Firearm to a Convicted Felon
Calvin Alphonso Turner, 32
This case is part of Project Safe Neighborhoods (PSN), which is the centerpiece of the Department of Justice's violent crime reduction efforts. PSN is an evidence-based program proven to be effective at reducing violent crime. Through PSN, a broad spectrum of stakeholders work together to identify the most pressing violent crime problems in the community and develop comprehensive solutions to address them. As part of this strategy, PSN focuses enforcement efforts on the most violent offenders and partners with locally based prevention and reentry programs for lasting reductions in crime.
G. Zachary Terwilliger, U.S. Attorney for the Eastern District of Virginia, Ashan M. Benedict, Special Agent in Charge of the Bureau of Alcohol, Tobacco, Firearms and Explosives' (ATF) Washington Field Division, and Kenneth A. Miller, Chief of Petersburg Police, made the announcement. Assistant U.S. Attorneys Angela Mastandrea-Miller and Peter S. Duffey are prosecuting the cases.
A copy of this press release is located on the website of the U.S. Attorney's Office for the Eastern District of Virginia. Related court documents and information is located on the website of the District Court for the Eastern District of Virginia or on PACER.
An indictment contains allegations that a defendant has committed a crime. Every defendant is presumed to be innocent until and unless proven guilty in court.
Washington Field Division


I recently read a lengthy article on the news website ProPublica about the myth of drug expiration dates. The really, really quick version is that medications are safe and effective years after the expiration date. If you want a little more background, keep reading.
Before a drug comes to market, as required by the FDA, it undergoes testing by the manufacturer to determine how quickly (or not) it breaks down. The FDA reviews the testing results, and then recommends an expiration date, which is usually 2-3 years. This ensures that the drug will be safe and effective if used during that time. Once a drug is expired, pharmacies, hospitals, and doctors offices are required to throw them away. Many consumers also do the same. But is a drug still safe and effective after the expiration date? And if so, for how long?
Drug manufacturers do not test drugs after the expiration date because there is no incentive, nor are they required, to do so. But a pharmacist for the California Poison Control System, and scientist at Cal-San Francisco recently tested some medications dating back 30-40 years. These included antihistamines, pain relievers, and stimulants. The findings surprised both men- the compounds in the drugs were essentially stable and just as potent as if they were new!
It turns out that the FDA has known this for years. The federal government has, for decades, been stockpiling large amounts of medications, antidotes, and vaccines at secure locations in case of a national emergency. The military, CDC, and the VA system also do not discard most expired medications, saving the government $600- $800 million a year. Another study done in 2006 also showed that many medications were stable after their expiration date. However, a few were not, including albuterol (for asthma), diphenhydramine (for allergies), and an anesthetic made from lidocaine . But there are no reports of anyone ever being harmed by taking an expired drug.
China has some of the highest rates of myopia (nearsightedness) in the world, and their government is trying to do something about it. It is estimated that 70% of Chinese teenagers are nearsighted. As part of an initiative to reduce the incidence of myopia by the year 2030, this past August, the Chinese government called for placing limits on the sale and use of video games. It has long been thought that there is a link between prolonged near work and myopia. Therefore, they want children to limit the use of electronic products for non-learning purposes to 1 hour per day and no longer than 15 minutes at a time.
Here's a quiz for you. Pictured below are well know celebrities/famous people when they were younger. Can anybody get all 9? I got 2 right. I'll post the results in a few days.
I definitely know three celebrity names. Four others I think I recognize. Thanks for posting!
So close. You missed one.
Thanks for posting the expired drug info, I almost discarded plain Mucinex dated expired December, 2018.
First of all, how did everyone get #5 Halle Berry correct? Secondly, you missed one- #2. #2 is Ben Stiller.
This is great! I only got 3 lol Thanks for the drug info and game!
You're welcome, Jody. Thanks for playing.


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England successfully retained their European titles!
May 6, 2012 • Tags: ESF, European Team Championships, Germany, Nuernberg • Categories: all posts, teams, tournaments
Both English teams have been able to retain der title to established as the leading force in Europe (photo: Jordan Mansfield)
England successfully retained their titles in the European Team Championships after a 3/0 men's victory over France and a 2/1 women's win over Ireland in in Nürnberg, Germany.
In the women's final Belfast's Madeline Perry, ranked 3 in the world, fought back from 2/1 down to beat world No2 Jenny Duncalf 13-11, 7-11, 3-11, 11-7, 11-8. But Laura Massaro steered the England ship back on course by beating Aisling Blake 11-1, 11-9, 9-11, 11-8, before Alison Waters clinched victory by defeating Laura Mylotte 11-2, 11-8, 11-2.
Top seeds England lined up against cross Channel rivals France in the men's final for the 12th time since 2000. Experienced 4th string Daryl Selby gave his team the best start with an 11-3, 11-13, 11-9, 11-9 win over Frenchman Gregoire Marche.
In the 2nd match James Willstrop beat world No3 Greg Gaultier 11-3, 8-11, 11-6, 11-1 to give England a 2/0 lead and Peter Barker then clinched the title after a 11-7, 11-5, 11-7 win over Mathieu Castagnet.
The victory marks England's 20th success in a row – and the 37th in total since the inaugural championships in 1976.

redpajama_set_name: RedPajamaCommonCrawl


Possible cause of unnatural mass death of wild birds in a pond in Nishinomiya, Japan: sudden appearance of toxic cyanobacteria.
Intestinal carriage of Yersinia pseudotuberculosis by wild birds and mammals in Japan.
Appl Environ Microbiol 1991 Apr;57(4):1152-5.


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Can dogs tell when you're pregnant?
Dogs have an astounding ability to sense change in the world around them, and that includes when their owner is pregnant.
After all, dogs are excellent at reading human body language and behavior, and there is even some evidence that dogs can detect when a person has cancer or is about to have an epileptic fit.
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Can dogs tell you're pregnant?
When a woman is pregnant, the hormones in her body are likely to alter her scent in some way. So, can dogs sense pregnancy? Because of their keen sense of smell, it's believed by many that a dog can detect a change in a woman even before she does — but it's mostly conjecture.
Can a dog tell if you're pregnant?
Remember, the amazing canine sense of smell can detect even the slightest change in odor. When it comes to moods, you simply cannot fool your dog. So it seems only natural that dogs will sense the mood and behavior changes that the woman of the house undergoes when she is pregnant.
Can dogs tell if you're pregnant?
Can puppies tell if you're pregnant?
While there is no study (yet) showing that dogs can sense pregnancy in humans, it's really not that much of a stretch to assume that dogs might be able to sense that their owners are pregnant. After all, during pregnancy your body is filled with a new cocktail of hormones.
Can pets tell if you're pregnant?
Yes, it's possible that cats can sense pregnancy even before you have early pregnancy signs. This is due to their excellent and refined sense of smell.
Can dogs tell when you're turned on?
Often, if a dog can smell it, the dog is going to explore it. Dogs use their senses to guide their lives and they count sniffing as getting to know someone. It's important that your dog gets a good read on you and how you're doing, so it's possible this will result in some anxiety and nervousness.
Can dogs tell when you're sad?
Can dogs tell when you're smiling?
When You're Smiling, Your Dog Probably Knows It. Dogs can learn to recognize smiles, a study indicates. Since we humans have no tails to wag, our best friends have to look elsewhere for signs we feel happy and friendly. A new study indicates dogs can learn to distinguish a smile, even on the faces of some strangers.
Can dogs tell when you're sick?
Can dogs tell when you're on drugs?
Dogs do not even know about "narcotics," per se. Detection dogs learn to detect volatile molecules that are components of drugs, rather than detecting the whole drug. And, of course, the dogs have no idea that what they're searching for is illegal; they just know that finding it earns them a reward.
Can dogs tell if you're pregnant before you know?
There's always a chance that even if you don't know you're pregnant, you're trying — and your behavior or routine may change accordingly in ways that your dog notices. "There have been extraordinary reports about olfactory senses of dogs. After all, during pregnancy your body is filled with a new cocktail of hormones.
Can dogs tell when you're drunk?
There are numerous reports about dogs being able to sniff out everything from minute traces of narcotics to the early stages of cancer, so assuming that they are unable to smell the alcohol on you is just plain crazy. Dogs can smell alcohol on your breath and body — they can even smell it if you were underwater.
How do dogs act when you're pregnant?
Here are several factors that may explain how dogs sense when their owner is pregnant. Change in odor—When a woman becomes pregnant, her body chemistry changes. Remember, the amazing canine sense of smell can detect even the slightest change in odor.
Do dogs follow you when you're pregnant?
Do dogs know when you're pregnant?
Do dogs sense when you're pregnant?
When you're pregnant, your hormones change, and this could affect the familiar smell of your skin that your dog knows and loves. Instead of saying that dogs smell pregnancy, it might be more accurate to say that dogs can possibly smell these hormonal changes.
Can dogs tell when you're mad at them?
Signs Your Dog Knows You're Mad. Dogs have been around humans for a really long time. As a result, they've learned to read our facial expressions, body language, and voices in a way that allows them to at least recognize what we're feeling. This includes anger.
Can dogs tell when you're about to go into labor?
Many dogs are very clingy when their human mom is pregnant. Your dog is probably doing this to make sure you are okay at all time because they know what is coming next. Additionally, many dogs will even go a step further and rub and heads and snouts on your belly on the day or day before you go into labor.
Can dogs tell when you're on your period?
Signs Your Dog Can Sense Your Period. To put it bluntly, your dog, with his or her acute sense of smell, can detect menstruation - even before it happens - by both odor (even if you're unable to smell it) and by the scent of your hormonal levels.
Do you poop more when you're pregnant?
Hemorrhoids — varicose veins in the rectum — are common during pregnancy as well. Your blood volume has increased and your uterus puts pressure on your pelvis. Constipation is another common pregnancy woe. It happens because pregnancy hormones slow the passing of food through the gastrointestinal tract.
Can dogs tell when your pregnant?
Can dogs tell when you are pregnant?
Can you tell when you're about to go into labor?
Here are some early signs of labor: Your baby "drops." If this is your first pregnancy, you may feel what's known as "lightening" a few weeks before labor starts, meaning the baby now rests lower in your pelvis. You might feel less pressure just below your ribcage, making it easier to catch your breath.
Can dogs sense if you're pregnant?
Do dogs get more clingy when you're pregnant?
That's why many women say that when they are pregnant, or have a newly born child in the house, their dogs will become much more affectionate and clingy. Some dogs may not act as crazy as they usually do, by not pulling or tugging or barking all the time, because they realize that it would stress you out.
Can dogs tell if you're crying?
Plenty of pet owners are comforted by a pair of puppy-dog eyes or a swipe of the tongue when their dog catches them crying. Now, new research suggests that dogs really do respond uniquely to tears. The results are what you might expect if dogs understand our pain, the researchers wrote, but it's not proof that they do.
Can dogs tell if you're scared?
Yes, if he knows you are afraid. Because dogs are experts at reading body language, they can quickly pick up on someone who is afraid of them. They can actually smell fear. When we are scared, sweat glands are more active which will produce "body odor" a dog can smell.
Can animals tell when your pregnant?
The answer, according to animal behavior specialists, is yes: pets probably can sense pregnancy. Cats and dogs have very refined senses of smell, and may pick up on these changes—even before a pregnancy test does. Pregnancy isn't the only human condition where animals have been known to sense changes before humans do.
Can puppies tell when your pregnant?
Can dogs tell if you're sad?
Do dogs know you're pregnant?
Can dogs tell when a woman is pregnant?
When can you tell your dog is pregnant?
During your visit, your vet can use ultrasound to see the growing puppies as early as 3 weeks in. Ultrasound is safe during pregnancy. If you don't take your dog to the vet until her 4th week of pregnancy, the doctor can feel your dog's belly to confirm puppies are on the way.
When can I tell my dog is pregnant?
An ultrasound or hormone test can confirm a pregnancy as soon as three weeks into the pregnancy. If you go in later, your vet can feel your dog's belly to confirm a pregnancy between days 28 to 35.
When can you tell if a dog is pregnant?
6 Signs of Pregnancy in Dogs Decreased Activity. If your dog easily becomes exhausted or is spending more time napping, it may indicate that she is pregnant. Changes in Appetite. Unusual Behavior. Enlarged or Discolored Nipples. Weight Gain and Enlarged Abdomen. Nesting Behaviors.
Can dogs tell if you're a good person?
Signs of a Dog Sensing a Good Person. Dogs can sense when someone is a bad or good person. They can even see only a person's eyes and tell whether he or she is a threatening or non-threatening person. Dogs respond to different moods according to their breed and personality type.
Does your dog know you're pregnant?
Change in odor—When a woman becomes pregnant, her body chemistry changes. This, in turn, can cause her distinct odor (an odor her dog knows intimately) to change. So it seems only natural that dogs will sense the mood and behavior changes that the woman of the house undergoes when she is pregnant.
Do dogs know if you're pregnant?
Can dogs tell if you're a dog person?
Dogs can sense when someone is a bad or good person. Your dog may not know the moral decisions a person has made, but he can pick up on signs of nervousness, fear, anger, and danger. Dogs notice specific things about humans that even other humans are not aware of.
Can a man tell when a woman is pregnant?
Most women determine that they are pregnant if they are sexually active and have missed a period. Nausea, breast soreness, and fatigue are also common symptoms in early pregnancy. Ultrasound or pregnancy tests are the only ways to immediately be sure that a woman is pregnant.
Can dogs sense when you're leaving?
Dogs may be oblivious if they're out for a walk or spending time with a dog sitter, but once they get to see you, they can sense something is wrong just by the smell of it. Literally, dogs smell when you're not at your happiest, whether that's anxiety or depression, and they look for a way to reach you.
Can dogs sense when you're in pain?
Can dogs sense when you're sick?
Can dogs sense when you're nervous?
Dogs can also sense stress or fear by using their keen sense of smell (they can detect when a person is sweating due to being anxious or afraid). If the owners are present and they are stressed about their dog getting a nail trim, the dog will feel their nervous energy.
Can dogs sense when you're on drugs?
Can you have a miscarriage before you know you're pregnant?
Sometimes, a pregnancy is far enough along that the miscarriage symptoms are noticeable, even if the woman didn't know she was pregnant to begin with. According to WebMD, you're probably having a miscarriage if you have these symptoms: Bleeding which progresses from light to heavy. Severe cramps.
Can dogs sense when you're moving?
Dogs tend to adjust much more easily to moves than cats. That's because new puppy owners are encouraged to socialize their puppy to get him used to new people, new smells and other dogs. So from the time they're young, dogs are out and about.
Can you have a period if you're pregnant?
While some women may experience intermittent vaginal bleeding while they are pregnant, it isn't possible to have a period. So, can you have a period while you're pregnant? The short answer is no. Since women don't ovulate — or release an egg — during pregnancy, they will not get their monthly period.
Can dogs tell if you are pregnant?
Can my dog tell im pregnant?
Can dogs tell if your pregnant?
Can a dog tell if your pregnant?
Can you get pregnant if you're not ovulating?
There are only six days during any cycle when a woman can get pregnant - the five days leading up to ovulation and the 24 hours after ovulation. This is because sperm can live for up to 5 days in a woman's body, and the ovum lives for only 12-24 hours.
Can your dog tell if your pregnant?
Can my dog tell I'm pregnant?
Can dogs sense when you're about to go into labor?
Training Dogs to Sense When You're Going Into Labor. You will not have to train your dog to sense when you are going into labor. Your dog will be able to sense this based on their biological instincts. They use their nose to sense changes in smell, which then alert them to react.
Can animals sense when you're sad?
Galvan and Vonk's finding suggests that cats are more in tune with human emotions than we thought. That does not mean they feel empathy. Still, even if cats do not truly understand our moods, the study still suggests that they can pick up on surprisingly nuanced human gestures.
Can you smell when you're sleeping?
While sound can disrupt sleep, scents cannot. People cannot rely on their sense of smell to awaken them to the danger of fire, according to a new Brown University study. Study participants easily detected odors when awake and in the early transition into sleep (Stage One sleep) but, once asleep, did not.
Can Cats sense when you're in pain?
We have known for a while that dogs are good at recognising human facial expressions. But this is the first convincing evidence that cats have the same capacity. Galvan and Vonk's finding suggests that cats are more in tune with human emotions than we thought. That does not mean they feel empathy.
Do dogs know when you're mad?
Your dog will know when you are mad. Dogs hate to disappoint and can sense the emotions and body language that comes with an upset "parent". When you are upset with your dog and he gives you those "sweet puppy dog eyes" he knows that you are upset and is hoping to change things.
Do Dogs miss you when you're gone?
Aw. Although it's still unclear whether dogs are aware of the length of time they're left alone for, research suggests that they're more excited to greet their owner if they're left alone for two hours than 30 minutes. But we do know that dogs process images faster than our slow human eyes do.
Do dogs know when you're helping them?
Can dogs sense when you're mad at them?
As the study above has shown, dogs can learn to differentiate between emotions, and thus react differently. If you want your dog to know that you're mad, they're probably going know without any training, because of your facial expressions and tone of voice.
How can you tell if a dog has a temperature when pregnant?
Your dog's body temperature will drop below 99 degrees Fahrenheit/37 degrees Celsius approximately 8 to 24 hours before whelping. Starting on day 60 of your dog's pregnancy, take her rectal temperature twice a day. Keep track of the temperatures in a log and watch for when her temperature drops at least 1 degree.
How do dogs know when you're sad?
Can a puppy tell if your pregnant?
Do dogs know when you're sick?
Do dogs know when you're sleeping?
It can be hard to know when your dog's sleep crosses a line from normal to too much, but here are some signs to watch out for: Excessive lethargy: if your dog is sleeping more than normal and also seems to lack energy even during the hours when it's awake, this may be a sign of a bigger issue.
Do dogs know when you're sad?
Do dogs know when you're smiling?
Do dogs know when you're arguing?
Dogs can sense when you are fighting or in an argument with someone, especially when the other person is right there with you. You can tell your dog knows when there is something wrong because they will show a few common signs that dogs emit when they can sense negative emotions.
How can you tell if your pregnant?
The most common early signs and symptoms of pregnancy might include: Missed period. If you're in your childbearing years and a week or more has passed without the start of an expected menstrual cycle, you might be pregnant. Tender, swollen breasts. Nausea with or without vomiting. Increased urination. Fatigue.
Can a xray tell if your pregnant?
According to the American College of Radiology, no single diagnostic x-ray has a radiation dose significant enough to cause adverse effects in a developing embryo or fetus. Some common diagnostic procedures include dental, chest, CT scan (head/chest), and abdominal view.
Can babies tell if your pregnant?
It's likely that your baby is showing earlier than your first pregnancy. If your toddler is nearing 18-months, you could tell her at around the same time as you announce your pregnancy to friends and family. She may take little notice until she can see your bump or feel the baby kicking.
How can I tell if cat pregnant?
How to tell if a cat is pregnant Darkened Nipples. At around three weeks, a pregnant cat's nipples will become darker in color and enlarged. Morning Sickness. Just like humans, a pregnant cat may also go through a period of being sick occasionally. Swollen Belly. Nesting. Positive Ultrasound.
Can dogs sense when you're having a nightmare?
According to these dog owners, if your dog is having a nightmare, you might notice the dog growling, crying, or whimpering. If you notice any of these signs, and your dog appears to be in distress, it might be a good idea to wake them up, carefully.
Can Cats sense when you're mad at them?
Can other dogs tell if a dog is pregnant?
A few weeks after going into heat, a dog can exhibit signs of pregnancy, such as enlarged nipples and increased appetite, without actually being pregnant. Check with your vet to make absolutely sure whether your dog is pregnant.
Do dogs know when you're singing?
The senses for animals are different than human sensory abilities as we know specifically from the sounds the dog hears that we don't. It is not just the pitch, but the flow of tones that catch a dog's attention. As we sing a gentle flowing, calming song, we produce serene surroundings for our dogs.
Do dogs know when you're coming home?
How do you tell a guy that you're cute?
To tell a guy you think he's cute, go right at it. Take a direct approach, if you are a very confident person. Write him a note and put your phone number in it, if you're shy or are a bit of a mysterious girl. Ask him to hang out one-on-one.
Do you poop when you're dehydrated?
Because watery stool can cause more fluid loss than usual, it can trigger dehydration and often accompanies it. The colon removes extra water from the stool to send to other parts of the body when you're dehydrated. This can slow bowel movements, causing bloating and constipation, according to Dr. McStay.
Do cats know when you're in labor?
As we discussed in part one, towards the end of your cat's pregnancy you should be taking her rectal temperature every day waiting for a sudden drop below 99 degrees. When labor begins, most cats pant and vocalize and may become restless and pace around like they are looking for something.
How do you know you're pregnant without a test?
The proof is in the pregnancy test. But even before you miss a period, you might suspect — or hope — that you're pregnant. Know the first signs of pregnancy and why they occur. Classic pregnancy signs and symptoms Missed period. Tender, swollen breasts. Nausea with or without vomiting. Increased urination. Fatigue.
How soon can vet tell if dog is pregnant?
Your vet can confirm a pregnancy with either a dog pregnancy test, which measures her hormone levels, from days 21-25 of her term, or by ultrasound from day 20-22. From around day 30 your vet will be able to carry out a physical examination to count how many puppies your dog is having.
How early can you tell if your dog is pregnant?
How early can you tell if a dog is pregnant?
A slight mucus discharge may occur around one month after mating. Her teats may become more prominent in colour and size around 30 days after mating, and you may also see them produce a semi-clear fluid. Similar to our "morning sickness", your dog may vomit a little in the early stages of pregnancy.
Can you tell if a dog is pregnant?
During your visit, your vet can use ultrasound to see the growing puppies as early as 3 weeks in. Ultrasound is safe during pregnancy. The vet may give your dog a blood test to check her hormone levels. Dogs have higher levels of a hormone called relaxin when they're pregnant.
How soon can I tell if my dog is pregnant?
When the vet gives the go-ahead, and the mating takes place, you need to know how to tell if a dog is pregnant by her behaviors and physical symptoms. You probably won't notice any pregnancy signs until your pooch has been pregnant for three weeks or more.
How can I tell if my dog is pregnant?
Here are 5 signs to watch for: Decreased Activity. If your dog easily becomes exhausted or is spending more time napping, it may indicate that she is pregnant. Changes in Appetite. Unusual Behavior. Enlarged or Discolored Nipples. Weight Gain and Enlarged Abdomen. Nesting Behaviors.
Can dogs tell if you are pregnant early?
They are also very observant and intuitive and know when something is up, so it's hardly surprising that dogs can also detect when women are pregnant. These hormonal changes can take place as early as within the first month, which means that a dog could sense your pregnancy before you are even aware of it.
Can a dog tell if a woman is pregnant?
Do animals know when you're sad?
What do you eat when you're lazy?
Good news -- there's a bunch of pretty nutritious, super quick (and, importantly, delicious) meals you can make when you're feeling lazy. Here's what four health experts eat on a lazy night in. Stir fry. Omelette. Porridge. Pasta. Frittata. Scrambled eggs. Salad. Steak.
How long before you can tell your dog is pregnant?
You probably won't notice any pregnancy signs until your pooch has been pregnant for three weeks or more. "Early signs of pregnancy can include morning sickness, energy level changes, and enlargement of nipples," says Dr. Coger. That said, she adds, "Some dogs will show none of these signs."
How can you tell if a dog has been pregnant?
Early Signs of Dog Pregnancy Decreased appetite. This is one of the first signs that your dog may be pregnant. Increased appetite. Decrease in energy. Swollen nipples. Change in nipple color. Behavioral changes.
How can you tell if a female dog is pregnant?
How long before you can tell a dog is pregnant?
Can dogs tell if a woman is pregnant?
Can dogs tell if their owner is pregnant?
Australian KelpieNorjackShepherd PitSmooth PoxerWhite Swiss ShepherdBrugBernefieJack-A-BeeUtonaganMastiff
Why do puppies eat poop and how do you stop it?
Can I have subway while pregnant?
What are grapes good for?
Why do dogs like to cuddle in the morning?
Do dogs have regular heart beats?
Is it normal for 1yr old to snore?
How long after my puppy's second injection can he go out?
How long after a dog dies does it start to smell?
Why do dogs roll in stinky things?
Can you adopt over 40?


Patsy is using Smore newsletters to spread the word online.
"What is this coaching thing?"
The fly-by is the way that I am most easily and most frequently used. Do you have a question that you need an answer to right now? Do you need a resource to help you implement a new strategy in your classroom? Do you want feedback/data on a specific strategy you are trying or on a goal you are working on as a teacher? Do you want the latest research to help you decide the best technique to try? Do you just want to come into my relaxing, calm, in the middle of nowhere office to sip coffee or eat chocolate? Well, those are all fly-bys. They can be done in a few minutes or a few days. They are on-the-spot and quick.
"Two Heads are Better Than One." So, together we will be constantly collecting student work, reviewing our plans and our chosen strategies and then reflecting on how what we're doing is affecting student learning. We will engage in action research to weed out ineffective strategies and strengthen the ones that are working. This process is messy and at times, frustrating. However, if we come in with an open-mind and a willingness to work together and reflect on our practices, it will be a very rewarding experience for the both of us.


Very lovely card! I like both cards, but do like the cleaner look of the first one quite a bit. Great job!
Loving both of these "hello" cards Marina, but the first one's colours appeal to me more. Love that little fox. He certainly does say hello with his little wave. Cute image. I also really like the sentiment placement. It's really effective at reserving white space on this card and keeping it CAS. Thanks for entering it at the Masculine "Anything Goes" Watercooler Wednesday challenge this week.
I also like your cute fox!
Amazing cards, Marina. I think the white background in the second attempt makes everything "pop" just that little bit more, but both cards are gorgeous! Love that adorable little fox, of course, and his friendly wave. Love those leaves gently falling to the ground. And love the overall look to this wonderfully clean and simple card. Thanks so much for joining our Watercooler Wednesday Challenge this week.
Both cards look great! That waving fox steals the show, but I like your bold sideways sentiment. Perfect to have a wave on the 'hello' challenge. How cute!
What a treat to see TWO of your darling foxes, waving hello to us! Love them both! And hello back to them!
Love the crisp look of your first card and the second has a lovely Autumn feel and your colouring is fab-being too self critical!
Hello Marina! Love your foxy autumnal card. Thanks for playing at AAA Cards.
Your little fox is totally adorable and I love the big bold sentiment! Thanks for playing along with CASology this week!
What a lovely big hello, and cute little fox. So happy you could join in the fun at CASology this week.
I love the effect and feel of Kraft paper, but for this design the white version makes the design feel extra crisp and clean.
Simply adorable card! Very cute card! Thanks for joining us at Watercooler Wednesday this week for our Masculine challenge!
Oh, I do love that hello sentiment! So big and bold, and the script is so pretty! Perfectly paired with your sweet fox...just too cute! Thanks for joining us at CASology!
Thanks for joining us at Watercooler Wednesday Challenges! Both cards are wonderful, I prefer the white card.
Such sweet cards!! I like the way the image pops on the white one. Such a cute image it is, too!
Both cards are lovely and your fox is adorable! Thanks for playing along with us at AAA Cards!


text:
Mate Bekavac, Clarinet
-> postponed to 2020
N.N., Piano
Mate Bekavac was born in Ljubljana, Slovenia in 1977 and received his first musical education with F. Trzan and D. Brlek in native Ljubljana. He continued his studies at University of Graz with B. Kovacs, then took his MA degree at Salzburg Mozarteum with A. Brandhofer. He also studied at Juilliard School of Music in New York under C. Neidich and in "cycle de perfectionement" at Paris Consrvatory (CNSM) with Michel Arrignon. He has won the Mozarteum 1992 award, the Eurovision Jury award in Warsaw 1994, Grand prix of the Yamaha competition in Vienna , amongst others.
He appeard as soloist with chamber orchestras Franz Liszt, Cappela Istropolitana, Camerata Israel, Moscow soloists Salzburg soloists, Munich soloists and Zagreb soloists, Orchester der Philharmonie der Nationen, Saarlandischen Rundfunk, Orchester der Oper in Frankfurt, Symphonie Orchester Basel and all Slovenian orchestras.
His special devotion and central part is chamber music, played with Gidon Kremer, Yuri Bashmet, Lyn Harrell, Heinz Holliger, Irena Grafenauer, Kuss-Philharmonia Berlin-, Arriaga-, Minguet and Doric string quartets, Elena Baskhirova, Khatia Buniatishvili, Katia Skanavi, Patricia Kopachinskaja, Sol Gabeta, Alina Ibragimova, Frans Helmerson, Nicolas Altstaedt, Claudio Bohorques, Maxim Rysanov, Antoine Tamestit, members of Orchester der Bayerischen Rundfunk, MET-orchestra New York and London Symphony orchestra.
He collaborated with conductors M. Jansons, B.Haitink, N.Harnoncourt, K.Masur, Z. Mehta, C.Davies, N.Jaervi, C.Mackerras, C.Hogwood, M.Perahia, I.Perlman. Frequently he is guest at festivals in Lockenhaus, Jerusalem, Les Museiques in Basel, Rheingau Musik Festival, Ludwigsburger Festspiele, Dubrovnik, Lucerne and Munich. As an orchestral musician he played solo clarinet in Chamber Orchestra of Europe, Mahler Chamber Orchestra and Royal Concertgebouw Orchestra.
Program and Preparation: the international concert repertoire. At least 3 works by different composers, one work from the epoch of Viennese Classics is recommended.
Languages: Slovenian, English, German


Love this jerky! Especially the new jerky & cheese!
I love the quality of this jerky. It's much better than what I usually get. I will buy again!
Ok this has to be the best jerky, I have ever tasted. Also like the fact that is has the minimal amount of ingredients necessary to make great tasting product.
Its good. And super tender.


text:
New Restaurant Alert
The Phoenix Ale Brewery Central Kitchen Opens Next Month in Central Phoenix
Lauren Saria April 5, 2016 9:00AM
It's been months since Okra, the second restaurant from the Crudo team, opened its doors at The Crown on Seventh in Central Phoenix. But since then, there hasn't been much action when it comes to restaurants opening in adaptive re-use projects.
Next month, however, that will change. The Phoenix Ale Brewery and Rich Stark, former CEO of NYPD Pizza, are set to open The Phoenix Ale Brewery Central Kitchen, a beer-and-food collaboration that will surely bring some more life to the 20,000 square-foot former retail complex.
The restaurant is expected to open in early May and is hosting job fairs to hire approximately 75 employees. The PAB Central Kitchen seeks "candidates of all experience levels to fill back-of-house and front-of-house positions," according to a press release.
If you're interested, you'll want to swing by the restaurant, located at 5813 North Seventh Street, on Wednesday, April 6, from 11 a.m. to 2 p.m. or 3 to 7 p.m. Interviews will be on the patio. Bring a resume.
For more information about the job fair or for updates on The Phoenix Ale Brewery Central Kitchen, visit The Phoenix Ale Brewery Central Kitchen website or Facebook.


Hotel Laika is set directly on Rimini's Rivabella seafront, giving you great access to the sea as well as the shops, bars and restaurants that line the promenade. Many of Hotel Laika's rooms offer beautiful sea views and balconies and some have air conditioning. Friendly and welcoming, this hotel provides free WiFi internet access at reception and free on-site parking. Hotel Laika's restaurant serves genuine regional cuisine, offering fish and meat menus as well as vegetable and dessert buffets.


Humane Animal Treatment Charity, Inc. ( A 501c3 IRS Approved Non-Profit) is proud to host this wine tasting event that offers you an exclusive opportunity to taste seven of the most popular wines from Eugéne Wine, a boutique micro vinification winery that passionately strives to consistently make superb wines that will exceed a wine lover's expectations.
Eugéne Wine has generously gifted our charity a more than ample supply from their renowned portfolio of wines to help us raise crucially needed funds for 501(C)(3) non-profit, no-kill animal organizations. The entire proceeds from our "Cause For Paws" wine tasting events go to these blessed animal rescue facilities who rescue unwanted, abandoned, suffering animals and prepare them to be adopted to loving homes. Now available, advance tax deductable tickets will ensure your place at this area's biggest fun-filled, interesting, educational, wine tasting fundraiser and social gala.
At our wine tasting events we recognize that food is a normal part of the wine-tasting process so we provide a complementary charcuterie table containing finger foods that pair well with the various premium Eugéne wines.
Our wine tasting events are no pressure light-hearted, lip smacking tasty, social fun. Attendees do not need to be an expert to enjoy themselves because we make learning new stuff about wine fun. You will be part of an interactive, educational, eat, drink and be merry atmosphere. So plan to be a part of an evening of tastings where everyone actively participates with fellow tasters, friends and others who have an interest in wine.
Every paid attendee will receive their own personal souvenir wine glass to be used by them at this event, In addition, each paid attendee will receive a free copy of, It's All About Wine the essential guidebook to further one's knowledge and appreciation of wine. Written by Gene Levine, vintner of Eugéne Wine. Additional copies are available for $10.00. Advance ticket purchasers who reserve their place in this event at least four weeks prior to the event (Jan, 26, 2017) will receive their copy of this guidebook in the mail – prior to the event.
Don't be left out. Purchase your advance tickets now by clicking on a red button below. Admission to this event is by donation only, payable through PayPal or by check – made payable to Humane Animal Treatment Charity, Inc, an IRS approved and recognized 501(C)(3) non-profit tax-exempt charity under Section 501(c)3 of the Internal Revenue Code. Our IRS identification number is 27-4371975. Additional donations at the event can be made by check, cash or by major credit cards.
Donation(s) are tax deductible to the fullest extent of the law; less the value of any goods or services received in exchange for the donation. Donors are advised to consult legal or tax counsel regarding their own tax situations.
Advance, tax deductable tickets are on sale now for this gala fundraising, social event. For more information call 386-454-0001 or to purchase tickets go online to www.humanetreatment.org.
Must be at least 21 years of age to attend. No exceptions please.


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People want access to their own genomic data, even when uninterpretable
European Society of Human Genetics
Glasgow, United Kingdom: The largest study to date of attitudes towards the use of genomic information shows that the majority of people want access to results from genome sequencing, even if these are not directly related to the condition for which the analysis has been undertaken. This applies even when the data are not health-related or are simply 'raw', a researcher will tell the annual conference of the European Society of Human Genetics today (Monday).
Dr Anna Middleton, a Principal Staff Scientist at the Wellcome Trust Sanger Institute, Cambridge, UK, will describe the results of a survey into the attitudes of the various groups involved in sequencing research - patients, public, health professionals, and genomic researchers - towards the types of genomic information they would be interested in receiving. Just under 7000 people from 75 countries took part in an on-line survey, advertised on social and traditional media, and by an email list-serve.
"We asked participants to imagine that they were taking part in sequencing research with the option to receive personal results, and carefully explained the sorts of results that might come from a sequencing study in ten short films. We found that 98% of participants wanted to know about genes linked to treatable conditions that were serious or life-threatening; they were still interested even if the chance of such a condition occurring was as low as 1%. What was important to them was being 'forewarned' about their future risk of disease so that they could take steps to protect their health. This makes sense, but we also found that 59% of those surveyed were interested in having access to their own raw data, even though, on its own, it would tell them nothing useful about their future health. Participants perceived a value a value in raw data that may or may not exist: 'if the scientists know it, I'd like to know it too.' They felt the genomic information simply 'belonged to them' and thus they should be able to have access to it, even if the reality was that they would do nothing with it," Dr Middleton will say.
Participants appeared to be excited and positive about genomics, and they also wanted to be connected to the research process; for example, they were keen that genomic researchers should keep re-analysing their data and report to them if there were new findings. But they also recognised that scientists had an important job to do in doing good quality research; the work of answering a particular research question should not be side-tracked by a necessity to supply personalised results. Participants said they were willing to forego the return of individual findings if the delivery of such data compromised the ability of scientists to focus on the answer to a research question.
"It would now be very helpful to explore the value that people put on genomic data. For example, would they pay for an interpretation and, if so, how much?" says Dr Middleton. "Creating clinical-grade health information in a research setting requires funding, resources, and strong clinical connections to the health professionals who will deliver it, explain it, and follow up the patient. This may be out of reach for many researchers. So if research participants expect personalised results, but they also don't want researchers to compromise their research in order to deliver such results, then would they be willing to pay for these services?
"What we did in our research is explore what people say they might do in a hypothetical situation, and what we need to do next is explore the actual experience of research participants who are given personal results from sequencing research. We know already that some research participants ask for their raw sequence files and so it would be really useful to follow such participants over time to see what they do with these. We also want to know more about the psychosocial impact of receiving genomic data and whether it has an emotional resonance that people didn't expect.
"Researchers have a responsibility not to harm their research participants, and if they are going to provide results, they need to do this in an ethical way. At the moment our genomics community agrees that if researchers choose to return results that could potentially be clinically actionable these need to be confirmed in a clinically accredited laboratory before they are returned, and there should be a clinician available to share the information with the patient and to provide screening services if necessary. For research participants who ask for their raw sequence data (that by their very nature, come with no interpretation), then they should be given a clear explanation of the limits of these data together with some signposts to services that they can access for interpretation and support. Without this there is a risk that research participants will turn up at the door of their GP and ask them what it all means." Dr Middleton will say.
"Whilst I feel that autonomy is important, and research participants do have the right to their own data, should they want them, we also have a responsibility to explain the reality of the difficulties with interpretation - and to do this without misleading people. By allowing research participants access to raw sequence data, they have the choice as to how these are explored and what sorts of information they would like to glean from them. However, they can only really do this when there is easy access to interpretation services that can be endorsed by health professionals and genomic researchers alike. Such services are not easily accessible currently and there is an urgent need to address this if sharing raw sequence data becomes a reality. Some of our participants mistakenly thought they could put their data into Google and an interpretation would pop out. Researchers mustn't leave their participants stranded, so they should only share raw sequence data together with an explanation of what can be done with this. We also have to think carefully about the potential impact of this on health services," she will conclude.
Mary Rice
mary.rice@riceconseil.eu
http://www.eshg.org
Deciphering Developmental Disorders Project, Health Challenge Fund, Wellcome Trust, UK Department of Health
European Society of Human Genetics Conference
MEDICAL/SCIENTIFIC ETHICS


We are pleased to offer domestic shipping through our shipping partner, the United States Postal Service (USPS).
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text:
High School Teachers Get Close Look at Superior Court as Seminars Are Launched
By ALISON LOMAS, Staf Writer
The Long Beach courthouse yesterday welcomed a dozen high school government teachers, who spent the day speaking with judges and sitting in on criminal proceedings as part of a Los Angeles Superior Court community outreach program.
The Teachers' Courthouse Seminars, are intended to give teachers a firsthand look at the judicial criminal justice system in action so that they can teach their students more effectively.
Approximately 90 teachers are expected to attend seminars in six courthouses around the county during the month of October, officials said.
"It's a great project because it educates teachers about the trial court so that they in turn can provide accurate information to their students. . .who will become jurors, citizens and tax payers, Judge Richard L Fruin said. Fruin is chair of the court's Community Outreach Committee.
The court has offered the seminars to teachers of Los Angeles Unified School District's 49 high schools on a pilot basis for the last two years, but decided to extend the invitation to other school districts this year.
The court sought the cooperation of school districts close to the courthouses where the seminars would take place, but any high school government teacher "who hears about it and wants to come is welcome," court spokeswoman Patricia Kelly said.
Teachers from both private and public schools are invited to attend.
The subject matter to be covered during the courthouse visits includes the structure of courts, the organization of the courthouse, court criminal procedures, criminal sentencing laws, constitutional issues involved in search and seizure and police interrogations, jury service and the court's web sites.
Fruin said that he wants the teachers to "see as many different criminal proceedings as possible" because the "criminal courts highlight the constitutional protections that citizens have when accused of crimes."
The programs are similar in their content, but the actual agenda depends on the criminal proceedings occurring in the courthouse on that day.
The educators are expected to observe arraignments, bail hearings, plea bargains, jury selection, juvenile sentencing and the court's drug-diversion program, according a statement by the court's information office, Kelly said. The seminars also give the teachers an opportunity to discuss constitutional rights and trial procedures with judges, prosecutors, public defenders and other court staff.
During the day-long seminar yesterday teachers from eight local high schools sat in on a suppression hearing, watched the court grant a trial continuance, and attended a preliminary hearing.
The group also witnessed a defendant in handcuffs and a blue jumper accused of domestic violence enter a no-contest plea after being informed of his constitutional rights. The teachers also had the opportunity to learn about the issues that arise in juvenile and family law proceedings.
Before or after each proceeding, the judge or commissioner presiding would explain the legal issues involved in that particular proceeding and the teachers were given an opportunity to ask questions.
At least 13 judges, two commissioners and one referee joined the teachers during lunch. In what Fruin referred to as an attempt to "humanize" the judges, each judicial officer spoke to the group.
Janet Lipson, a teacher at Long Beach Poly High School praised the program:
"The opportunity to spend a day at a local court accompanied by court officials is one all government teachers should get to experience. Besides seeing many aspects of the justice system, the chance to speak with individual judges and have questions answered was invaluable."
Anthony B. Rogers, also from Poly, said he was "grateful" for the opportunity to spend a day "watching the court system in action." He said the time spent in the juvenile court was particularly useful.
At the end of the day's program, each participant was given a copy of a CD-ROM designed to help explain the justice system through a step-by-step description of a criminal case from the time of filing to the disposition.
The CD-ROM, funded by a $22,000 grant from the Judicial Council, was the product of a cooperative effort between the court and the Los Angeles County Office of Education. It features three simulated hearings based on reports of actual cases decided in California in 2001 and 2002.
The scenarios were written by Superior Court Judge John Segal and depict a motion to suppress, the withdrawal of a guilty plea, and a "three-strikes" sentencing, presided over by Judges Larry Fidler, Lance Ito and Tricia Bigelow.
Bigelow told the MetNews she was "really touched" that so many people were willing to volunteer their time to put together the CD-ROM. Fruin credited Bigelow with casting the attorneys, bailiffs, clerks and other court personnel who appear in the courtroom scenarios featured on the CD-ROM.
The CD program also includes lesson plans developed by Laura Westerman from the county Office of Education and Dr. Bryan Borys, director of the court's organizational development and education department. The lesson plans include the appellate opinions on which the scenarios were based.
Fruin said he hopes the government teachers will use the CD-ROM as a tool to teach their students about the trial courts.
Charlene Sampson, a teacher at Cabrillo High School, said that her classroom is equipped with the technology to use the CD-ROM, but suggested that other schools may not be technologically advanced enough to take advantage of such a high-tech teaching tool.


Michael Wild was the nearly man of British musical theatre in a career that saw him produce more than 40 such works. His few West End runs were short-lived despite his obvious gift as a tunesmith.
He began performing at Reading School and was twice recipient of the drama medal bearing the name of former pupils and leading British filmmakers the Boulting Brothers. Aged 12, he turned to composing and drew attention for his ballet score for The Necklace at the Embassy Theatre while still a student at RADA.
After National Service, he trained at the Guildhall School of Speech and Drama, producing the revue Well, Really! with fellow student Jim Murphy in 1952.
Seen in Reading in 1957, his first full musical, Pardon My Prejudice, a reworking of Jane Austen's Pride and Prejudice, was written while Wild – who also directed his shows – was at teacher training college.
Several adaptations followed: of Thomas Hardy in Fairwell, My Fancy (1958), Oscar Wilde in Earnestly Yours (1960) and Frances Hodgson Burnett's Little Lord Fauntleroy in 1969, which The Stage reported as being "the most commercial musical of the last 20 years".
Maggie, another adaptation, of JM Barrie's What Every Woman Knows, enjoyed a brief run at the Shaftesbury Theatre in 1977. It marked Anna Neagle's last appearance on a West End stage and won Anna Sharkey a Society of West End Theatre (now Olivier) award for best performance in a musical.
Wild had larger ambitions for his portrait of the entertainer Josephine Baker, claiming interest from soul diva Diana Ross for a mooted Broadway run that never came to fruition. It eventually achieved a showcase performance at the Fortune Theatre in 1989.
In the early 1990s, Hastings' White Rock Theatre staged revivals of Pardon My Prejudice, Maggie and Little Lord Fauntleroy.
An occasional performer, he was the piano accompanist for Tom McGrath's Mr Laurel and Mr Hardy (Mayfair Theatre, 1976), was seen in cabaret and headlined An Evening with Michael Wild and Friends at the Latchmere Theatre in 1990.
He published an autobiography, Composer, Known Only to God and Anna Neagle, in 2018.
Michael John Wild was born on May 13, 1931 and died on November 11, 2018, aged 87.


text:
Andrews University (1)
Carroll College (1)
Columbia Law School (3)
Grove City College (1)
Gustavus Adolphus College (1)
Imperial College of Science/Technology/Medicine - University of London (1)
Indian Institute of Technology - Bombay (1)
New York University School of Law (1)
Okayama University (1)
Pace University School of Law (1)
Pennsylvania State University (1)
Rutgers University (1)
Santa Clara University (1)
The George Washington University Law School (3)
(-) The Ohio State University (1)
Tuskegee University (1)
UCLA School of Law (1)
University of Arkansas (1)
University of California - Berkeley (4)
University of California - Berkeley School of Law (6)
University of California - Hastings College of Law (2)
University of California - Los Angeles (5)
University of California - Los Angeles Medical School - Department of Biological Chemistry (1)
University of California - San Diego (2)
University of California - Santa Cruz (1)
University of Connecticut (1)
University of Massachusetts (1)
University of San Diego (1)
University of Science & Technology of China (1)
University of Washington - Seattle (1)
Vanderbilt University Law School (1)
Villanova University (1)
Bryan J. Johnson
bryan.johnson@knobbe.com


text:
Transplants for the elderly in myeloma
Gareth J. Morgan
1INSTITUTE OF CANCER RESEARCH AND ROYAL MARSDEN HOSPITAL
Gareth J. Morgan; Transplants for the elderly in myeloma. Blood 2013; 122 (8): 1332–1334. doi: https://doi.org/10.1182/blood-2013-07-510941
multiple myeloma, older adult
In this issue of Blood, Gay et al provide important new information that can be used to design future phase 3 trials.1
The key elements of modern treatment strategies: sequential treatment approach for myeloma. Ongoing treatment with an induction phase, followed by intensification (transplant), consolidation, and a maintenance phase.
They chose a dose of melphalan known to be tolerated in this age group and augmented its activity by using cassettes of treatment using novel agents during induction, consolidation, and maintenance and evaluated its activity and tolerability in the 65- to 75-year-old age group. It is clear that it is well tolerated, with minimal early mortality and is associated with good response and survival data. It is possible to compare these outcomes with representative historical data sets including the Medical Research Council (MRC) study where the overall survival (OS) in the nontransplanted group for melphalan-prednisone vs cyclophosphamide-thalidomide-dexamethasone was 30.6 vs 33.2 months, respectively, and for patients in the transplanted group >64 years of age was 53 months.2 In the Intergroup Français du Myélome (IFM) 99-06 study comparing melphalan-prednisone with melphalan-thalidomide-prednisone and with autologous stem cell transplant (ASCT) with 100 mg/m2 of melphalan, the OS in each group was 33.2, 51.6, and 38.3 months, respectively.3 Thus, the 5-year OS of 63% in the current study is good, using this novel sequential approach to treatment, which should now be evaluated formally against current standard approaches for this age group.
Maximizing cure rates by personalizing therapy is one of the major aims of modern myeloma treatment. With respect to achieving cure, one of the major prerequisites is the achievement of a stringent complete response (sCR) as assessed by multiparameter flow cytometry. It has been increasingly possible to achieve this aim in younger patients treated with ASCT where such sCRs are associated with optimum clinical outcomes.4 The integration of novel therapies into the context of ASCT has further improved overall and sCR rates and has changed the prevailing treatment paradigm which now comprises induction, transplant, consolidation, and maintenance treatment blocks. These blocks of treatment are delivered with the aim of sequentially reducing tumor bulk and incorporate the concept of using combinations of drugs incorporated into cassettes of treatment, which when combined have synergistic effects maximizing response rates. In addition, at each treatment phase, different cassettes comprising different combinations of drugs are given with the aim maximizing the chance of inducing apoptosis in resistant subclones and reducing the risk of relapse. More recently, the aim of maximizing responses has incorporated the concept of "maintenance treatment," whereby ongoing treatment is given aiming to control the biology of residual clonal populations and killing myeloma stem cell populations coming into cell cycle.5,6
The incorporation of these ideas has revolutionized the treatment of younger patients, but it has come at the price of potentially increasing toxicity that needs to be managed. This is perhaps not an issue for the 40% of patients who develop myeloma before the age of 60, but for the majority of patients who develop myeloma beyond this age, toxicity is a significant issue. ASCT is considered the standard treatment of younger fitter patients, but there is no consensus in terms of an age cutoff above which ASCT is contraindicated. The initial IFM study used 60 years as an age cut point, whereas the MRC VII study used 65 years.7,8 In subsequent studies, including Myeloma IX, the MRC group used doctor and patient preference to decide on treatment pathway and included patients up to the age of 73 years in the transplant strategy. In an analysis of this study based on 5-year age cohorts, it was clear that there were differences in survival for the 55 to 60, 60 to 65, and 65 to 70 year groups, but mortality was not an issue. Interestingly, although a small number of patients over the age of 70 were included in the study, none made it to the transplant procedure for a number of reasons, including failure to collect stem cells and doctor or patient preference, making 70 a pragmatic age cutoff above which a full dose of 200 mg/m2 is generally inappropriate.2
The definition of an age cutoff of 70 years raises the issue of what is the best way of treating this age group, as well as younger patients who are considered too frail to receive a full dose of melphalan. One way of making high-dose melphalan more applicable is to reduce the dose. The standard dose of melphalan is 200 mg/m2, which reflects the fact that 3 positive studies comparing transplant to standard therapy used this dose,8 whereas studies using lower doses were not associated with positive survival benefits.3,9 In a variation on the single dose of melphalan approach, a sequential 100 mg/m2 approach has been evaluated and was found to be tolerable but again it did not improve survival.10
Conflict-of-interest disclosure: G.J.M. has participated in advisory boards for, received payment for lectures and development of educational presentations from, and received travel support from Celgene, Millenium, Novartis, Merck, and Johnson & Johnson.
Magarotto
Crippa
Bortezomib induction, reduced-intensity transplantation and lenalidomide consolidation-maintenance for myeloma: updated results.
NCRI Haematological Oncology Study Group
Cyclophosphamide, thalidomide, and dexamethasone (CTD) as initial therapy for patients with multiple myeloma unsuitable for autologous transplantation.
Intergroupe Francophone du Myélome
Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial.
Rawstron
de Tute
Minimal residual disease assessed by multiparameter flow cytometry in multiple myeloma: Impact on outcome in the Medical Research Council myeloma IX study.
J Clin Oncol
The genetic architecture of multiple myeloma.
Barlogie
Anaissie
van Rhee
The Arkansas approach to therapy of patients with multiple myeloma.
Best Pract Res Clin Haematol
Harousseau
Single versus double autologous stem-cell transplantation for multiple myeloma.
Medical Research Council Adult Leukaemia Working Party
High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma.
Sonneveld
van der Holt
Segeren
Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON)
Intermediate-dose melphalan compared with myeloablative treatment in multiple myeloma: long-term follow-up of the Dutch Cooperative Group HOVON 24 trial.
Zamagni
Prospective, randomized study of single compared with double autologous stem-cell transplantation for multiple myeloma: Bologna 96 clinical study.


text:
»Administrative Rules Related
»Department of Safety and Professional Services (SPS)
»Chs. SPS 301-399 ; Safety, Buildings, and Environment
»Chs. SPS 326-360; General, Part II
»Chapter SPS 326
subch. II of ch. SPS 326 Subchapter II — Definitions
SPS 326.10 SPS 326.10 Definitions. In this chapter:
SPS 326.10(1) (1) "Ability to pay" means a manufactured home community occupant's financial capacity to meet the manufactured home community occupant's water and sewer service financial obligation.
SPS 326.10(2) (2) "Agent" means a village, city or county designated by the department to issue permits and make inspections of the manufactured home communities.
SPS 326.10(3) (3) "Basic unit" means a manufactured home without hitch, awnings, cabanas, storage unit, carport, garage, windbreak, non-winterized porch or similar appurtenant structures.
SPS 326.10(4) (4) "Department" means the department of safety and professional services.
SPS 326.10(5) (5) "Disconnection" means an event or action taken by the manufactured home community operator or manufactured home community contractor to terminate or discontinue the provision of water and sewer service, but does not include cessation of service at the request of a manufactured home community occupant.
SPS 326.10(6) (6) "Dispute" means a statement or question by a manufactured home community occupant alleging a wrong, grievance, injury, dissatisfaction, illegal action or procedure, dangerous condition or action committed or created by a manufactured home community operator or manufactured home community contractor.
SPS 326.10(7) (7) "General service charges" means charges billed to the manufactured home community occupant by the manufactured home community operator or manufactured home community contractor and intended to recover the cost of supplying water and sewer service.
SPS 326.10 Note Note: The expenses typically recovered by general service charges are operation and maintenance expenses, taxes, depreciation, or debt service. Expenses such as late payment charges, non-sufficient funds check charges, or reconnection charges are not typically recovered through general service charges but are typically separate, additional charges applied to the manufactured home community occupant's account.
SPS 326.10(8) (8) "Manufactured home" has the meaning specified under s. 101.91 (2), Stats.
SPS 326.10 Note Note: Under s. 101.91 (2), Stats., "manufactured home" means any of the following:
SPS 326.10 Note (am) A structure that is designed to be used as a dwelling with or without a permanent foundation and that is certified by the federal department of housing and urban development as complying with the standards established under 42 USC 5401 to 5425.
SPS 326.10 Note (c) A mobile home, unless a mobile home is specifically excluded under the applicable statute.
SPS 326.10(9) (9) "Manufactured home community" has the meaning specified under s. 101.91 (5m), Stats.
SPS 326.10 Note Note: Under s. 101.91 (5m), Stats., "manufactured home community" means any plot or plots of ground upon which 3 or more manufactured homes that are occupied for dwelling or sleeping purposes are located. "Manufactured home community" does not include a farm where the occupants of the manufactured homes are the father, mother, son, daughter, brother or sister of the farm owner or operator or where the occupants of the manufactured homes work on the farm.
SPS 326.10(10) (10) "Manufactured home community contractor" has the meaning specified under s. 101.91 (6m), Stats.
SPS 326.10 Note Note: Under s. 101.91 (6m), Stats., "manufactured home community contractor" means a person, other than a public utility, as defined in s. 196.01 (5) (a), who, under a contract with a manufactured home community operator, provides water or sewer service to a manufactured home community occupant or performs a service related to providing water or sewer service to a manufactured home community occupant.
SPS 326.10(11) (11) "Manufactured home community occupant" has the meaning specified under s. 101.91 (7), Stats.
SPS 326.10 Note Note: Under s. 101.91 (7), Stats., "manufactured home community occupant" means a person who rents or owns a manufactured home in a manufactured home community.
SPS 326.10(12) (12) "Manufactured home community operator" has the meaning given in s. 101.91 (8), Stats.
SPS 326.10 Note Note: Under s. 101.91 (8), Stats., "manufactured home community operator" means a person engaged in the business of owning or managing a manufactured home community.
SPS 326.10(13) (13) "Meter" means an instrument installed to measure the volume or rate, or both, of flow of water delivered through it.
SPS 326.10(14) (14) "Person" means an individual, firm, trust, partnership, association or corporation.
SPS 326.10(15) (15) "Protective services emergency" means a threat to the health or safety of a community resident because of the infirmities of aging, other developmental or intellectual disabilities, or the frailties associated with being very young.
SPS 326.10(16) (16) "Remote outside meter" means an analog device attached to a building or structure that displays the reading of the base meter through electronic pulses sent from the base meter.
SPS 326.10 Note Note: Remote outside meters are considered part of the manufactured home community operator's or manufactured home community contractor's metering configuration.
SPS 326.10(17) (17) "Site" means a plot of ground within a manufactured home community designed for placement of one manufactured home.
SPS 326.10(18) (18) "Small manufactured home community" means a manufactured home community containing fewer than 6 individual sites that are rented or offered for rent for the accommodation of a manufactured home.
SPS 326.10(19) (19) "Street" means the paved or surfaced portion of the roadway between curb faces.
SPS 326.10 History History: CR 04-135: cr. Register February 2006 No. 602, eff. 3-1-06; correction in (5) made under s. 13.92 (4) (b) 6., Stats., Register December 2011 No. 672; CR 14-017: r. (4), renum. (5) to (20) to (4) to (19) Register August 2014 No. 704, eff. 9-1-14; 2019 Wis. Act 1: am. (15) Register May 2019 No. 761, eff. 6-1-19.
subch. III of ch. SPS 326 Subchapter III — General Requirements
SPS 326.11 SPS 326.11 Location.
SPS 326.11(1)(1) Every manufactured home community and manufactured home within the community shall be located on a well-drained area and shall be properly graded to prevent the accumulation of stormwater or other waters.
SPS 326.11(2) (2) A manufactured home shall be located on soil that provides sufficient soil bearing capacity to support the manufactured home.
SPS 326.11 History History: CR 04-135: cr. Register February 2006 No. 602, eff. 3-1-06.
SPS 326.12 SPS 326.12 Physical layout.
SPS 326.12(1)(1) Sites.
SPS 326.12(1)(a)(a) Each site shall be clearly delineated on plans submitted to the department or its agent for approval.
SPS 326.12(1)(b) (b) Each basic unit shall be located on a site so that there is at least a 10-foot clearance between basic units. The clearance requirements shall be exclusive of a parking area.
SPS 326.12(1)(c) (c) No basic unit may be located closer than 10 feet to any of the following:
SPS 326.12(1)(c)1. 1. Any building such as a pump house, the office building for the community, a laundry building or a recreational building, except a garage or accessory structure belonging to the site or manufactured home community occupant.
SPS 326.12(1)(c)2. 2. Any property line of the community.
SPS 326.12(1)(c)3. 3. Any street within the community.
SPS 326.12 Note Note: See chs. SPS 320 to 325 for additions and alterations to manufactured homes.
SPS 326.12(2) (2) Parking. Parking spaces in a ratio of one and one half for each site shall be provided and maintained in good condition.
SPS 326.12(3) (3) Streets.
SPS 326.12(3)(a)(a) Streets shall conform to the minimum widths specified in Table 326.12.
Table 326.12
Street Widths, in Feet - See PDF for table
SPS 326.12(3)(b) (b) Where parking on the street is prohibited, "no parking" signs shall be provided.
SPS 326.12(3)(c) (c) Streets shall be graveled or paved, maintained in good condition, have natural drainage, and be able to support the imposed loads for occasional use of fire apparatus as determined in consultation with the local fire department.
SPS 326.12(4) (4) Existing manufactured home communities.
SPS 326.12(4)(a) (a) Except as provided in par. (b), manufactured home communities or a section of a manufactured home community that were in existence prior to 1962 need not comply with subs. (1) to (3) unless the department determines that non-compliance endangers the health or safety of community occupants.
SPS 326.12(4)(b) (b) Any manufactured home community expansion shall comply with subs. (1) to (3) and other applicable parts of this chapter.
SPS 326.12(4)(c) (c) Any modification of a manufactured home community that existed prior to 1962 relating to the size of the basic units, the separation between basic units or the placement of basic units on a lot in relationship to streets and other buildings shall be permitted by the department unless the department determines that the modification endangers the health or safety of community occupants. Any modification of a manufactured home community which did not exist prior to 1962 shall comply with subs. (1) to (3) and other applicable parts of this chapter.
SPS 326.12(4)(d) (d) Manufactured home communities or a section of a manufactured home community that were constructed between 1962 and March 1, 2006 shall comply with the following requirements for the width of 2-way streets within the community: At least 32 feet if parking is permitted on both sides of the street, 24 feet if parking is permitted on one side of the street and 18 feet if parking on the street is prohibited.
SPS 326.12 History History: CR 04-135: cr. Register February 2006 No. 602, eff. 3-1-06; correction in (3) (a) made under s. 13.92 (4) (b) 7., Stats., Register December 2011 No. 672; CR 14-017: am. (1) (c) (intro.), 1., 2. Register August 2014 No. 704, eff. 9-1-14.
SPS 326.13 SPS 326.13 Fire hydrants. For manufactured home communities and community expansions constructed after March 1, 2006, fire hydrants shall be provided in accordance with ch. NR 811 when the required water supply is available.
SPS 326.14 SPS 326.14 Plumbing systems. Water and sewer systems owned by a manufactured home community operator or manufactured home community contractor shall be constructed and maintained in compliance with chs. SPS 381 to 387.
SPS 326.14 Note Note: The connection and use of a public water or sewer system is regulated under s. 281.45, Stats.
SPS 326.14 History History: CR 04-135: cr. Register February 2006 No. 602, eff. 3-1-06; correction made under s. 13.92 (4) (b) 7., Stats., Register December 2011 No. 672.
SPS 326.15 SPS 326.15 Adequacy of water supply. Each manufactured home community operator or manufactured home community contractor shall furnish a continuous and adequate supply of potable water to its manufactured home community occupants.
SPS 326.16 SPS 326.16 Electricity.
SPS 326.16(1)(1) Manufactured home community electrical connections shall meet the requirements set forth in ch. SPS 316.
SPS 326.16(2) (2) A manufactured home community operator may request an electric utility provider to disconnect the electrical service to a site where an electrical overload or other dangerous condition exists in nonconformance with ch. SPS 316.
SPS 326.16(3) (3) An authorized employee or agent of the department may order a manufactured home community operator to make the request specified in sub. (2).
SPS 326.16 Note Note: Chapter SPS 316 adopts the National Electrical Code (NEC). See Article 550 Part III of the NEC for information relating to electrical connections for manufactured homes. See Article 240 for overcurrent protection.
SPS 326.16 History History: CR 04-135: cr. Register February 2006 No. 602, eff. 3-1-06; correction made under s. 13.92 (4) (b) 7., Stats., Register December 2011 No. 672; CR 14-017: renum. section 326.16 to (1), cr. (2), (3) Register August 2014 No. 704, eff. 9-1-14.
SPS 326.17 SPS 326.17 Garbage and rubbish.
SPS 326.17(1)(1) All garbage not disposed of through a garbage disposal unit connected with the sewage system shall be kept in separate, leak proof, non-absorbent containers equipped with tight-fitting covers unless otherwise protected from flies and insects, and the contents shall be disposed of as often as necessary to prevent decomposition or overflow.
SPS 326.17(2) (2) Garbage and rubbish containers shall be maintained in a clean and sanitary condition. The use of wooden or paper containers for storing garbage and rubbish is prohibited.
SPS 326.17 Note Note: Local ordinances may require the separation of garbage and recyclable materials.
SPS 326.17(3) (3) This section does not prohibit the use of dumpsters in a manufactured home community.
SPS 326.18 SPS 326.18 Management.
SPS 326.18(1)(1) Availability. The manufactured home community operator or a designee in charge of the manufactured home community in the absence of the operator shall, during reasonable hours, be available in the community, in close proximity to the community or via electronic means.
SPS 326.18(2) (2) Registration of owners. The manufactured home community operator shall keep a register of all owners and occupants of manufactured homes located in the manufactured home community, and shall permit the department or its agent to inspect the register at all reasonable times and upon reasonable notice. The register may be kept in an electronic form. If the register is being stored at a location different than the licensed address, the operator shall disclose the storage location to the department upon request.
SPS 326.18(3) (3) Maintenance. The manufactured home community operator shall maintain the manufactured home community in a clean, safe, orderly and sanitary condition at all times.
SPS 326.19 SPS 326.19 Duties of occupants. All owners and other occupants of manufactured homes in a manufactured home community shall do all of the following:
SPS 326.19(1) (1) Register with the manufactured home community operator.
SPS 326.19(2) (2) Maintain their site in a clean, orderly and sanitary condition at all times.
SPS 326.19 History History: CR 04-135: cr. Register February 2006 No. 602, eff. 3-1-06; CR 14-017: am. (intro.), (1) Register August 2014 No. 704, eff. 9-1-14.
SPS 326.20 SPS 326.20 Other municipal fees. A manufactured home community contractor or a manufactured home community operator may pass along to a homeowner a municipal charge imposed on the community or its occupants on a schedule to meet the obligations imposed by the municipality or municipal utility notwithstanding the terms of the lease.
SPS 326.20 History History: CR 14-017: cr. Register August 2014 No. 704, eff. 9-1-14.
subch. IV of ch. SPS 326 Subchapter IV — Water and Sewer Service
/code/admin_code/sps/safety_and_buildings_and_environment/326_360/326 true administrativecode /code/admin_code/sps/safety_and_buildings_and_environment/326_360/326/II/10/19 Department of Safety and Professional Services (SPS) Chs. SPS 301-399 ; Safety, Buildings, and Environment administrativecode/SPS 326.10(19) administrativecode/SPS 326.10(19) section true
Published under s. 35.93, Stats. Updated on the first day of each month. Entire code is always current. The Register date on each page is the date the chapter was last published.


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Charity 'advised mum to force her son, 7, to live as a girl'
Ashitha NageshSunday 8 Oct 2017 8:56 am
The boy, 7, was reportedly forced to live as a girl (Picture; Shutterstock)
A transgender charity has reportedly been banned from contacting a family after the mother forced her seven-year-old son to live as a girl.
Mermaids UK has also been criticised for advertising 'same day' cross-sex hormone treatments for children – a treatment banned by the NHS, because it causes irreversible changes and can compromise fertility later in life for anyone under 16.
In a High Court case, reported last year, Mr Justice Hayden removed the child – known only as 'J' – from his mother after finding she had caused him 'significant emotional harm' and 'pressed [him] into a gender identification that had far more to do with his mother's needs and little, if anything, to do with his own'.
After the judgement, the Sunday Times reported, the charity Mermaids attacked the 'horrific decision' and insisted that J did in fact identify as a girl, and said there was 'no evidence at all to support this judge's views'.
However, it has now been claimed that the charity has been 'ordered to have nothing to do with this child following their removal'.
The charity was reportedly ordered not to be in contact with the family (Picture: Mermaids UK)
J was being home-schooled and dressed in girls' clothes, the court found. After being removed from his mother, the boy was sent to live with his father and was sent to school, and has since 'asserted his own masculine gender' by living life as a boy, the judgement said.
Until last Friday the youth section of the charity's site featured a message from Dr Birgit Möller, a doctor based in Hamburg, offering fast-track hormone treatment for kids.
'If the families are interested we would set up a long evaluation appointment at our clinic (3-4 hours) and afterwards an appointment with the endocrinologist,' Möller wrote. 'In case of an indication for hormone treatment he would prescribe it the same day.'
Mermaids UK then claimed it was not the subject of the court order, but actually it was the family that had been instructed to contact it.
They added that they vehemently disagreed with the way the case had been represented in the Sunday Times, and that they were actively seeking legal advice.
Mermaids UK's statement in full
Mermaids was recently approached by a journalist with a series of enquiries concerning Mermaids' involvement with the court judgement following the case of 'Child J' in October 2016. The case was covered extensively in the national media at the time.
The story published today in the Sunday Times (8/10/17) refers to this case and references Mermaids. Mermaids supported the mother during the court case, although none of our representatives were present at any of the proceedings as they were conducted in a 'closed family court'. While the court documents have been sealed, a public summary judgement can be found here: http://www.bailii.org/ew/cases/EWHC/Fam/2016/2430.html
Contrary to what is implied in the Times article, Mermaids has not been banned from contact with the child by the high court, and Mermaids was directly referenced only once during proceedings, to state that the mother had been receiving support from the charity. Following the proceedings, the mother informed us that the judge had ordered the child should have no further contact with the charity. While we have not received any legal notice to support this statement, we have respected this request.
We are disappointed to note that while we informed the journalist of the above facts, they have chosen to publish this article. While we appreciate that there is currently an interest by the media in transgender children, it is very unhelpful to publish an article which could undermine the only national charity supporting them.
All of us engaged with gender diversity and supporting gender-questioning and transgender youth are familiar with negative reactions based on ignorance, fear and prejudice. This makes it even more important that the UK media report on this subject in a truthful and non-sensational manner.
While Mermaids has been recognised by, and received numerous awards from respected institutions, the impact of such negative reporting has a direct impact on the families and young people we support.
Mermaids will continue to offer much needed support to families and young people, and to provide education and guidance to organisations and professionals, and maintain our objective to strive towards making the world a fully accepting and inclusive place for gender non-conforming and transgender children and young people.
Mermaids is in active discussion with a lawyer regarding misinformation in the Sunday Times article.
ChildrenLGBTSchoolTransgender
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1Community Compact Member - Governor Baker created the Community Compact Cabinet (CCC), in order to elevate the Administration's partnerships with cities and towns in the Commonwealth. Compact members chose among a list of Best Practices to pursue. One of the Best Practices is Complete Streets. Municipalities receive additional points on their policy and project application for their Compact membership and Complete Streets Best Practice choice. Membership numbers represent the status at the time of registration. Many municipalities signed Compacts after registering for this Program.
2Approval Dates - The document approval dates provided indicate when MassDOT approved those documents. Click on the date to retrieve the document to determine the date that the municipality approved their Policy or developed their Prioritization Plan.


Jes Goodwin | Azazel's Bitz Box.
Officio Assassinorum. The Order of Imperial Assassins. The face of death to whomever is unlucky enough to see them, and many who never even catch a glimpse of their killers.
This is the "Head 1" version of the model. I think I have the alternative version, unpainted, somewhere. It utilises the same torso and body, and given the "throwing grenade" pose of the torso, I doubt we're going to get a radically different model when I do eventually find and paint him.
The Culexus Assassin, of course was released last out of the four (five?) Imperial Assassin types. The first, obviously was the Rogue Trader-Era "Ninja" Assassin, of no fixed temple. Now my memory is a little sketchy, but I recall the original being superseded over the course of three months worth of White Dwarf by the trio of the Vindicare (Sniper), the Callidus (Close Combat Shapeshifter) and the Eversor (All-out Psycho-Killer Berserker). Later on, with Codex: Assassins, they introduced the Culexus, who is a psychic "null" and a thing called the Animus Speculum bolted onto their gigantic, Xenomorph-like heads. When the eye of the Animus opens, focused "negative psychic energy" is unleashed and does a right number on any Psykers nearby, and in particular on its target.
Having read through Index 2 to see what this guy is like in-game, I can see he's a bit of a glass cannon, and appropriately nasty against psykers. Assassins were a nasty surprise to anyone who came near them back in 2nd edition, which was when I most often employed Assassins – this fellow in particular against a friend who's Slannesh army was fond of rather potent psykers.
I'm not sure how often a weapon like this will manage to see the tabletop in my games of 8th, which will largely be focused on smaller, friendly games for some time as the forces are built up. Perhaps he could be rolled out for especially large games? Certainly once we get to the stage of Daemon Princes and Greater Daemons being rolled out to the table, he'd have a place then.


text:
Q: creating a plug in that would tap into save/update action of posts What's a good plug-in that taps into the update post or save post action that allows admins to enforce rules such as if a user selects a category with the ID 5 then he also has to select at least one category from the the XYZ custom taxonomy etc - or that update/save won't go thru.
I'd like to write my own rules as to who ( which roles ) can do what and so on.
My plan is this.
Get a well-written plug-in and use that as the boiler plate for customizations.   So, I can just go into the source code of that  plug in and inject all kinds of business logic that is specific to my web site.
Any leads towards this goal is really appreciated.

A: I don't know of any plugins that do this, and I'm not sure you'll find one. The closest I can find is the "Mandatory Field" plugin. The specific tasks that you might want are so varied, that I wonder whether a non-bloated plugin that let you customize the validation is out there.
With that said, you'll want to look into the save_post hook. There are quite a few questions about that hook on this very site (such as this one). If you're looking for a code-snippet to modify, I'd start by looking through those questions.
Also, even if you do manage to write a good validation plugin with the save_post hook (btw, I'd use the term "validation" in your future questions and queries as that's really what you're trying to accomplish), I'd consider augmenting it with some client-side jQuery validation. I'd imagine it would be very annoying to have the "Publish" or "Update" button not take the expected action since this is a relatively rare feature to add to a WordPress site. By creating some live validation (backed up by the server-side stuff) would be a much better user experience.

A: I know that Advanced Custom Fields does that.
I keep citing it, but I promise I'm not affiliated...

From a fast analysis, this is the code that does it, but couldn't track how it's being hooked...
$('form#post').live("submit", function(){
    do_validation();

    if(acf.valdation == false)
    {
        // reset validation for next time
        acf.valdation = true;

        // show message
        $(this).siblings('#message').remove();
        $(this).before('

' + acf.validation_message + '

');

        // hide ajax stuff on submit button
        $('#publish').removeClass('button-primary-disabled');
        $('#ajax-loading').attr('style','');

        return false;
    }

    $('.acf_postbox:hidden').remove();

    // submit the form
    return true;
});

redpajama_set_name: RedPajamaStackExchange


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VIEWPOINT: Expose the Hidden Curriculum
December 1, 2022 by Madison Fox-Moore 1 Comment
It is no secret that, as a university with more students from the top 1% of the income scale than the bottom 60%, Georgetown University's wealth distribution greatly favors the upper class. While Georgetown has strived to increase the representation of low-income students on campus, the social impact of socioeconomic disparities remains the elephant in the room for its less advantaged students. Elite universities have a duty to rectify the invisibility of class privilege to those who hold it; Georgetown can do so by expanding existing programs such as the class "Mastering the Hidden Curriculum" to expose the realities of socioeconomic diversity to its privileged student body.
In 2004, Georgetown joined the growing effort of schools like Notre Dame, Brown and Northwestern to increase the representation of First-Generation Low Income (FGLI) students at elite universities through the Georgetown Scholars Program (GSP). The GSP supports FGLI Hoyas through grants, mentorship, advocacy and community building, which have enjoyed widespread success. The graduation rate for GSP students is 94%, which is 3.6 times higher than the national graduation rate for first-generation college students.
One of the most valuable GSP resources is the "Mastering the Hidden Curriculum" (MHC) course. This two-credit course is open to all students, but GSPers receive priority registration, and the course is largely guided by its two GSP Teaching Assistants. The course is meant to equip students with the skills and cultural capital to navigate Georgetown's academic community and collegiate environment," and it largely succeeds in this endeavor.
From discourse on the unique identity of FGLI students to presentations from the Cawley Career Education Center, the MHC course provides invaluable resources for its students. Classes focus on the power of privilege, the persistence of classist structures on college campuses and the diversity of FGLI experiences. For me, as a first-year student who has never before had the courage to publicly identify as FGLI, the power of the MHC course came from its ability to create an atmosphere where socioeconomic diversity was undeniably visible and welcome.
This class, however, falls short in its potential; FGLI students are unfortunately all too familiar with the structural barriers faced not only when applying to elite universities, but also when attending them. These obstacles are present daily in the cost of going out, the financial stress of purchasing books and the unrelenting onslaught of "How have you never been to …?"
It is not the duty of FGLI students to adapt to the dominant culture of wealth at Georgetown. It is the duty of Georgetown to implore all its students to be cognizant of the harsh reality of economic inequality.
In a nation where 44% of millionaires identify as "middle class," the privilege of wealth is often a bubble. This bubble blinds upper class Americans to the privilege associated with socioeconomic status: cultural capital. Defined as "institutionalized widely shared, high status cultural signals … used for social and cultural exclusion," elite cultural capital manifests itself in knowledge of office hours, campus resources and the unspoken mechanisms of higher education. Without the privilege of elite college preparatory resources, FGLI students often lack awareness of the need to use office hours to cultivate relationships with professors and the career preparation that universities offer. This effective denial of resources will continue, so long as the holders of cultural capital remain blind to their privilege.
By expanding access to the MHC course to all students, Georgetown can begin to deconstruct the class bubble. Instead of only teaching FGLI students how to adjust to a campus with very little socioeconomic diversity, Georgetown can make the realities of socioeconomic diversity known to all of its students. This would work to create a more prepared, mindful student body. Georgetown prides itself on molding future public servants, but in order to create better leaders, this education must holistically encompass America's diversity.
Georgetown should transform the MHC course into a 3-credit class that fulfills the university's engaging diversity requirement. Georgetown mandates that students take two courses with the engaging diversity attribute to ensure that students recognize "the plurality of human experience," yet out of the 54 courses offered for the Spring 2023 semester that satisfy this requirement, very few mention class, socioeconomic diversity or economic inequality. Georgetown has failed to meaningfully address the reality of class for far too long, and it is imperative that its curriculum acknowledges socioeconomic diversity as a meaningful component of the human experience.
The MHC course should continue to be offered as it stands for FGLI students, as its community-building atmosphere provides refuge from the often overwhelming culture of privilege on the Hilltop. The course's aims, however, should be expanded to educate students of all backgrounds.
First-Generation Low Income students have a home in the GSP at Georgetown, but this is not enough. The university has a responsibility to make its students well-rounded citizens, and this includes instruction on the privilege of wealth.
Madison Fox-Moore is a first-year student in the College.
About Madison Fox-Moore
Melony says
Excellent points!