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A 24-Year-Old Man With a Left Frontal Brain Mass
Based on this clinical scenario and the accompanying image, understand how to arrive at a correct diagnosis.
JAMA Clinical Challenge
Adrienne L. Carey, MD1; Muhammed U. Khan, MD2; N. Cary Engleberg, MD3 Author Affiliations
1Internal Medicine–Pediatrics Residency Program, Department of Internal Medicine, University of Michigan Health System, Ann Arbor
2Department of Medicine, Central Michigan University, Saginaw
3Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Health System, Ann Arbor
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A healthy 24-year-old man presented with 1 week of headache, gait imbalance, and coordination difficulties. His mother reported that he had experienced personality changes. He denied any fevers, chills, night sweats, or weight loss. He reported smoking marijuana and denied tobacco and intravenous drug use. He is sexually active, with multiple male partners.
On examination, he was alert and oriented, with a temperature of 36.3°C, blood pressure of 131/90 mm Hg, heart rate of 94/min, respiratory rate of 18/min with pulse oximetry of 98% on ambient air, and a body mass index of 28.1 (calculated as weight in kilograms divided by height in meters squared). Neurologic examination was significant for hyperreflexia in all extremities, bilateral shoulder weakness, and right-sided pronator drift. Laboratory results showed a white blood cell count of 3600/μL (73.5% neutrophils, 16.4% lymphocytes, 7.8% monocytes, 1.4% eosinophils, 0.6% basophils); the remainder of the complete blood cell count and comprehensive metabolic profile was unremarkable. The result of a human immunodeficiency virus (HIV) type 1 antibody test was positive, and CD4 cell count was 73/mm3. Results of serologic testing for Toxoplasma gondii IgG were negative. Computed tomography (CT) imaging of the brain showed a left caudate nucleus and lentiform nucleus lesion with mass effect on the left lateral ventricle (Figure, left panel). Fluid-attenuated inversion recovery magnetic resonance imaging (MRI) of the brain confirmed the presence of an aggressive mass lesion extending through the corpus callosum (Figure, right panel). CT of the chest, abdomen, and pelvis and spinal MRI were unremarkable.
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Primary CNS lymphoma (PCNSL)
B. Obtain a brain biopsy
The key to the diagnosis in this case was an imaging finding of an aggressive solitary lesion suggesting malignancy. The most common malignant brain mass in patients with AIDS is PCNSL, particularly in individuals with CD4 cell counts less than 100/mm3. Brain tumors arising from CNS tissue and metastatic malignancies are possible but less likely. Since PCNSL is an Epstein-Barr virus (EBV)–associated B-cell lymphoma, a positive CSF polymerase chain reaction (PCR) assay is highly suggestive of the diagnosis. In this case, a lumbar puncture (option C) was contraindicated because of imaging consistent with increased intracranial pressure. Other causes of brain mass in patients with human immunodeficiency virus (HIV) are toxoplasma encephalitis and progressive multifocal leukoencephalopathy. The latter does not manifest with a mass effect as seen in this case, but toxoplasma encephalitis can present as a solitary, aggressive mass on MRI. This patient had a negative toxoplasma IgG serologic status, making toxoplasmosis unlikely. Had he presented subacutely, had multiple ring-enhancing lesions on MRI, and/or had a positive toxoplasma serologic status, a treatment trial with 10 to 14 days of sulfadiazine and pyrimethamine for toxoplasmosis would be reasonable before considering a brain biopsy (option D). However, the rapid progression, lack of above-mentioned features, and possibility of PCNSL required more urgent diagnosis and treatment. Antiretroviral therapy (ART) is clearly indicated and was given to the patient (option A); outcomes with PCNSL improve when the viral load declines and CD4 cells recover. However, confirming the diagnosis (option B) is vital before initiating antitumor therapy.
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Corresponding Author: N. Cary Engleberg, MD, Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Health System, 3119P Taubman Center Box 5378, 1500 E Medical Center Dr, Ann Arbor, MI 48109 (cengleb@med.umich.edu)
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.
Additional Contributions: We thank the patient's mother for providing permission to share the patient's information.
Gopal S, Patel MR, Yanik EL, et al. Temporal trends in presentation and survival for HIV-associated lymphoma in the antiretroviral therapy era. J Natl Cancer Inst. 2013;105(16):1221-1229.PubMedGoogle ScholarCrossref
Antinori A, Ammassari A, De Luca A, et al. Diagnosis of AIDS-related focal brain lesions: a decision-making analysis based on clinical and neuroradiologic characteristics combined with polymerase chain reaction assays in CSF. Neurology. 1997;48(3):687-694.PubMedGoogle ScholarCrossref
Corr P. Imaging of neuro-AIDS. J Psychosom Res. 2006;61(3):295-299.PubMedGoogle ScholarCrossref
Corcoran C, Rebe K, van der Plas H, Myer L, Hardie DR. The predictive value of cerebrospinal fluid Epstein-Barr viral load as a marker of primary central nervous system lymphoma in HIV-infected persons. J Clin Virol. 2008;42(4):433-436.PubMedGoogle ScholarCrossref
Antinori A, De Rossi G, Ammassari A, et al. Value of combined approach with thallium-201 single-photon emission computed tomography and Epstein-Barr virus DNA polymerase chain reaction in CSF for the diagnosis of AIDS-related primary CNS lymphoma. J Clin Oncol. 1999;17(2):554-560.PubMedGoogle Scholar
Lee AM, Bai HX, Zou Y, et al. Safety and diagnostic value of brain biopsy in HIV patients. J Neurol Neurosurg Psychiatry. 2016;87(7):722-733.PubMedGoogle ScholarCrossref
Rosenow JM, Hirschfeld A. Utility of brain biopsy in patients with acquired immunodeficiency syndrome before and after introduction of highly active antiretroviral therapy. Neurosurgery. 2007;61(1):130-140.PubMedGoogle ScholarCrossref
Koralnik IJ. Approach to HIV-infected patients with central nervous system lesions. http://www.uptodate.com/contents/approach-to-hiv-infected-patients-with-central-nervous-system-lesions. Accessed November 28, 2016.
Rubenstein JL, Gupta NK, Mannis GN, et al. How I treat CNS lymphomas. Blood. 2013;122(14):2318-2330.PubMedGoogle ScholarCrossref
Holdhoff M, Ambady P, Abdelaziz A, et al. High-dose methotrexate with or without rituximab in newly diagnosed primary CNS lymphoma. Neurology. 2014;83(3):235-239.PubMedGoogle ScholarCrossref


And here is the final of the four family portraits. They're such a good-looking family, aren't they?
And here is her beautiful daughter. These may be the biggest eyes I've ever painted.
Can you see where yesterday's boy got his beautiful eyes?
The sun was just starting to come up behind the cedar swamp on this morning; it hadn't yet reached the snowy marsh. Later in the day we discovered coyote tracks heading purposefully south out on the ice.
I haven't had a chance to photograph what I've been working on these last few days, so here is another cute little boy from before the holidays.
Tarzan spent some time sitting on my shoulder while I painted today. As you can see, however, he likes to have my undivided attention.
As I was skiing home across the marsh, I turned and looked behind me toward the west. The clouds were backlit by the sun on its way down, with everything in shadow except their glowing edges.
This picture is from one of my last days in Michigan last week, coming back across the frozen marsh at the end of an afternoon ski, with a sky ranging from pale turquoise on the horizon to deep sky blue up above, with a faint, tiny crescent moon high over it all. This is one of my favorite spots on earth.
I think what I liked best about painting this girl was her pleasant self-assuredness. This is how I imagine Anne of Green Gables looked.
Here is the brother to yesterday's doggie. This little guy is a bit smaller, but with just as much personality. I found that it's fun getting a dog's expression right.
I now do pet portraits! This pooch is a Papillon, and his enormous ears do look like butterfly wings. I'm not often drawn to small dogs, but this little guy and his brother were so full of personality and so adorable that they won me over.
Speaking of pets, our household has a tiny new member—Tarzan! As you can see, he's making it a little difficult to focus on my painting.
I'm thrilled to announce that I am now represented by the online art gallery Fifty Artists. Fifty Artists sells one-of-a-kind paintings for under $500, and they have some really wonderful art on their site. Please check them out!
I've neglected my blog for the last few days--we've been spending lots of quality time in lines at the airport. I still haven't made it home, but I am with family and am warm and cozy. Here's another pretty girl.
It's always easier to paint someone when they're not talking. But for whatever reason, I find myself initiating conversations with some people as I paint. And then I have to ask them to be quiet and hold their mouth still so I can paint it. I don't know why I do that. This man was one of those. Just fun to talk with, I guess.
Cutie-pie, with her dark eyes and curls.


What does it mean to "see" God?
(From St. Ireneaus) "There is one God, who by his word and wisdom created all things and set them in order. His Word is our Lord Jesus Christ, who in this last age became man among men to unite end and beginning, that is, man and God.
The prophets, receiving the gift of prophecy from this same Word, foretold his coming in the flesh, which brought about the union and communion between God and man ordained by the Father. From the beginning the word of God prophesied that God could be seen by men and would live among them on earth; he would speak with his own creation and be present to it, bringing it salvation and being visible to it. He would free us from the hands of all who hate us, that is from the spirit of sin, and enable us to serve him in holiness and justice all our days. Man was to receive the Spirit of God and so attain to the glory of the Father.
The prophets, then, foretold that God would be seen by men. As the Lord himself says: Blessed are the pure of heart, for they shall see God. In his greatness and in expressible glory no one can see God and live, for the Father is beyond our comprehension. But in his love and generosity and omnipotence he allows even this to those who love him, that is, even to see God, as the prophets foretold. For what is impossible to men is possible to God.
By his own powers man cannot see God, yet God will be seen by men because he wills it. He will be seen by those he chooses, at the time he chooses, and in the way he chooses, for God can do all things. He was seen of old through the Spirit in prophecy; he was seen through the Son by our adoption as his children, and he will be seen in the kingdom of heaven in his own being as the Father. The Spirit prepares man to receive the Son of God, the Son leads him to the Father, and the Father, freeing him from change and decay, bestows the eternal life that comes to everyone from seeing God.
*What is Byssus? – Byssus is a cloth of exceeding fine texture used by the ancients. Fit for Royalty, a King, a High Priest, and God. Known as "sea-silk," it is more rare and precious than gold. Made from the long tough silky filaments of Pinna Nobilis mollusks that anchor them to the seabed–strong enough to resist the extreme hydrodynamic forces of the sea. Byssus has a shimmering, iridescent quality which reflects light. Byssus is extremely delicate, yet strong at the same time. It resists water, weak acids, bases, ethers, and alcohols. It can't be painted, as it does not retain pigments, it can only be dyed; and then, only purple. It can also last for more than 2000 years.
Byssus is mentioned in the Bible forty times–For just a few examples: in Genesis, Pharaoh took off his ring from his hand, and put it on Joseph's hand, and arrayed him in clothes of byssus, and put a gold chain on his neck. (Genesis 41) The curtains of the tabernacle (Exodus 26) were twined with byssus. Kingly and priestly garments were made with byssus. (Exodus) Solomon made a veil for the Holy of Holies with cherubim embroidered upon it in byssus.
The Veil of the Holy Face of Manoppello is also made of rare, precious byssus silk. The skill needed to weave a byssus veil as fine as the Veil of the Holy Face of Manoppello is exceedingly great. Chiara Vigo, known as "the last woman who weaves byssus" has said that neither she or anyone alive today could duplicate the gossamer-thin Veil, which is sheer enough to read a newspaper through. The weave is so delicate, she says, that only the nimble fingers of a very skillful child could weave something so fine.
It has been speculated–perhaps even the young Blessed Virgin Mary learned to weave byssus, as a young child in the temple, for the priestly garments. Perhaps, she herself wove this particular miraculous Veil with her own pure hands, which was placed as a face-cloth (sudarium) on the Face of Jesus in the tomb, and is thought to have recorded the very moment of the Resurrection of Jesus, true God and true Man, High-Priest and King!


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Home » Evolution » Is evolution the missing link to understanding mental health?
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Is evolution the missing link to understanding mental health?
Posted by Nicole Mlynaryk on August 22, 2019 in Evolution, genetics, Mental Illness | Leave a comment
What evolutionary theory can teach us about mental illness
Mental health care has become an increasingly frequent topic in our national dialogue, and with good reason. A 2017 survey reported that nearly 1 in 5 American adults live with a mental illness [1], yet the availability of effective treatment remains scarce. The reasons for this discrepancy are widespread, but from a scientific standpoint, much of the struggle lies in understanding the complex origins of each disorder. The high heritability of most mental illnesses suggests a strong genetic component, but our environment also affects our vulnerability to mental illness (nature and nurture). Scientists and clinicians study both topics in hopes of uncovering how each disorder develops, but some now argue that in order to find better treatments, we also need to understand why these disorders exist. The human brain has been shaped over hundreds of thousands of years, with evolution selecting for traits that helped our species survive and thrive. So why do we still have so many genes that make us struggle? Why did our remarkable cognitive capacity come with such a susceptibility to disorder? The field of evolutionary psychology suggests that looking at mental health from an evolutionary perspective will be critical to addressing our mental health crisis, the same way it has reframed our approach to treating cancer, infections, and metabolic disorders [2]. So what exactly does this evolutionary framework entail?
Many advances in evolutionary medicine begin with the following core concept: bodies are shaped by natural selection to maximize reproductive success, not health or longevity. In the case of cancer, this idea made scientists wonder if we are best at fighting tumors during our reproductive years. They further suggested that instead of trying to destroy a tumor completely, it may actually be better for the body to simply control the damage until the reproductive period is over [3]. This theory could help explain why cancer rates increase with age, while also inspiring new research questions and treatment plans. Instead of using therapies that try to eliminate all cancer cells, we could harness the body's built-in system for keeping tumors in check. This powerful approach to studying disease is just starting to be applied to illnesses of the brain.
When it comes to mental disorders, there are currently three major theories [4,5] that try to explain why they exist at such high frequencies, despite the fact that many of them reduce a person's fecundity (how many children you have) [6]. By taking our evolutionary history into account, these ideas aim to make sense of the genetic and environmental causes of mental illness. When we understand how our brains were designed in the first place, we can also learn how best to treat them.
The first theory is the balancing selection hypothesis, where evolution seemingly balances the positive and negative effects of a gene. Genes come in different variations, called alleles, and you have two varieties of every gene (one from each parent). Some alleles increase susceptibility to disorder more than others, but there are several reasons why evolution might have supported the existence of these riskier alleles. For example, you may inherit an allele that is associated with a disease, but is also very useful for other things. A classic example is sickle cell anemia, where having two copies of a particular variant of the hemoglobin gene gives you the disease, but having just one protects you against malaria. In the context of mental health, it's been suggested that the same alleles that contribute to schizophrenia may have also been integral in supporting human language and creativity [7]. Balancing the costs and benefits of an allele might explain why it continues to be passed on, despite its role in mental illness.
In addition to having different variations of a gene, you can also have multiple copies of it. For example, humans have many more copies of the DUF1220 gene compared to our primate ancestors. The more copies of DUF1220 a primate species has, the larger their brains are [8], which suggests this gene was pretty important to our cognitive evolution. But as it turns out, having more copies of DUF1220 is also associated with increased risk and severity of schizophrenia and autism [9,10].
It's important to note that not all traits are all-or-nothing; many exist on a continuum where having a moderate amount of the trait is useful, but extremes lead to disorder. This may be an important way of thinking about depression and anxiety, which include some behaviors that are actually helpful when used appropriately. For example, a major symptom in both disorders is rumination, or repetitive thinking. Excessive rumination can make you dwell on negative thoughts or replay unpleasant situations. On the other hand, being able to focus on a problem for an extended period of time can be quite useful for solving it. So this process that creates distress in excess may have initially evolved to support critical thinking and threat management. Even low mood, reduced motivation, and social isolation have been described as evolutionary tools for energy conservation [11]. These traits inform us to change our circumstances (don't keep doing something that isn't good for you), and can be used as social signals of defeat to prevent further aggression and encourage others to help. Adopting this sort of view would significantly change our perception of these symptoms, and perhaps even our clinical treatment of them. For example, alternative treatments could support the beneficial aspects of a trait instead of trying to get rid of it completely, i.e. promoting productive analytical thinking in a depressive patient rather than discouraging rumination altogether [11].
A second theory is the environmental mismatch hypothesis, which suggests that a trait may have been good in ancient times, but is detrimental in a modern environment or culture. For example, we know that our ancestors' ravenous appetite for sugar was useful for maximizing caloric intake when it was hard to come by. But this trait has become quite dangerous now that sugary resources are everywhere. In fact, the same neural pathways that motivated us to seek out these food rewards may have been later co-opted to drive other addictive behaviors. This concept also applies to traits that were previously neutral, but have become problematic as societal demands change. Some psychologists describe dyslexia as a form of neurodiversity that arose from natural differences in neurodevelopment and cognition. It's our culture's sudden reliance on written language systems that everyone can conform to that leads these individuals to now be labeled as disordered [12].
This set of ideas may explain some of the nature/nurture interactions that contribute to mental illness, especially since human cultures have been changing much more rapidly in recent history. We have a nervous system that was designed to carry out specific tasks within a tight-knit community, and we are now forcing it to adapt to complex new problems in a social structure that spans the globe. Between our largely sedentary lifestyles, shifting sleep patterns, virtual social interactions, and delayed gratification on increasingly abstract goals, there's a lot of environmental mismatch to consider.
The third theory is the polygenic mutation-selection balance hypothesis. Unlike the previous two ideas which try to explain why risky alleles are maintained over time, this theory emphasizes that they actually were removed throughout our evolution. The issue is our mental health depends on a very large number of genes, so there are a lot of opportunities for some of them to be risky, and new mutations appear all the time. One study estimated that each human carries ~500 mutations that are bad for brain function [13], but whether or not someone develops a disorder is based on the cumulative effect of their specific combination of mutations. This makes it very difficult to pinpoint the mechanism for each disorder because they develop slightly differently in each person.
There is also growing concern about new mutations appearing at a faster rate than the older ones can be removed. Whenever a reproductive cell (egg or sperm) is made, a new mutation can form and be passed down to a child. The majority of these new mutations come from the father, because more mutations accumulate each time new sperm are made. Since men are often having children later in life, these new mutations are becoming more frequent [14]. Support for the polygenic theory comes from the fact that rarer disorders like schizophrenia and autism have been linked to both newer mutations and increased paternal age [15,16]. On the other hand, more common disorders like depression and anxiety are likely to be evolutionarily older (not caused by random new mutations). Consistent with this idea, they are not as affected by increased paternal age [17].
This theory may be the most accurate and all-encompassing explanation of the genetic forces that contribute to mental illness, but also the hardest to design treatments for. Progress will likely require large numbers of patients to have their whole genomes sequenced in order to find genes worth targeting (a challenging feat).
The relative contribution of various factors to different mental disorders. Figure from [4].
These and other ideas will continue to be assessed as we search for the causes of harmful mental illnesses. The reality is likely to be a mix of them all. And yet, despite the useful insights and predictions each theory offers, these concepts are not a part of traditional clinical training, let alone the public perception of mental health. Most clinicians would agree that evolution has shaped the adaptive features of our nervous system, but few take advantage of this perspective when searching for the reasons things can go awry. Adding these ideas to the mix could critically shape the way we conceptualize mental illness in this country. Perhaps we would reevaluate which genes and traits are most important to treat, and develop more effective strategies to do that. Maybe describing these disorders within this larger biological framework provides some comfort to patients whose struggles have been stigmatized. It may also be time to make individual and societal efforts to reduce the modern environmental mismatches that cause us distress. But we can at least be certain that this evolutionary approach will generate new testable hypotheses that reveal a more complete understanding of the origins of mental illness. As a therapy session might suggest, sometimes we have to look back at our past in order to really progress forward.
[1] Substance Abuse and Mental Health Services Administration. (2018). Key substance use and mental health indicators in the United States: Results from the 2017 National Survey on Drug Use and Health (HHS Publication No. SMA 18-5068, NSUDH Series H-53).
[2] Gluckman PD, Low FM, Buklijas T, Hanson MA, Beedle AS. (2011). How evolutionary principles improve the understanding of human health and disease. Evolutionary Applications. 4(2):249–263.
[3] Hochberg ME, Thomas F, Assenat E, Hibner U. (2013). Preventive Evolutionary Medicine of Cancers. Evolutionary Applications. 6(1):134–143.
[4] Uher R. (2009). The role of genetic variation in the causation of mental illness: an evolution-informed framework. Molecular Psychiatry. 14:1072–1082.
[5] Durisko Z, Mulsant BH, McKenzie K, Andrew PW. (2016). Using Evolutionary Theory to Guide Mental Health Research. The Canadian Journal of Psychiatry. 61(3):159–165.
[6] Power RA, Kyaga S, Uher R, et al. (2013). Fecundity of patients with schizophrenia, autism, bipolar disorder, depression, anorexia nervosa, or substance abuse vs their unaffected siblings. JAMA Psychiatry. 70:22–30.
[7] Crow TJ. (1995). Aetiology of schizophrenia: an evolutionary theory. International Clinical Psychopharmacology. 10(3):49–56.
[8] Dumas LJ, O'Bleness MS, Davis JM, et al. (2012). DUF1220-domain copy number implicated in human brain-size pathology and evolution. American Journal of Human Genetics. 91:444–454.
[9] Quick VBS, Davis JM, Olincy A, Sikela JM (2015). DUF1220 copy number is associated with schizophrenia risk and severity: implications for understanding autism and schizophrenia as related diseases. Translational Psychiatry 5: e697.
[10] Davis, JM, Searles VB, Anderson N, et al. (2014). DUF1220 dosage is linearly associated with increasing severity of the three primary symptoms of autism. PLoS Genet, 10: e1004241.
[11] Durisko Z, Mulsant B, Andrews P. (2015). An adaptationist perspective on the etiology of depression. Journal of Affective Disorders. 172:315–323.
[12] Protopapas A and Parrila R. (2018). Is Dyslexia a Brain Disorder? Brain Sciences. 8(4):61.
[13] Keller MC and Miller G. (2006). Resolving the paradox of common, harmful, heritable mental disorders: which evolutionary genetic models work best? Behavioral and Brain Sciences. 29:385–404.
[14] Crow JF. (1999). Spontaneous mutation in man. Mutation Research. 437(1):5–9.
[15] Reichenberg A, Gross R, Weiser M, Bresnahan M, Silverman J, Harlap S et al. (2006). Advancing paternal age and autism. Archives of General Psychiatry. 63:1026–1032.
[16] Malaspina D, Corcoran C, Fahim C, Berman A, Harkavy-Friedman J, Yale S et al. (2002). Paternal age and sporadic schizophrenia: evidence for de novo mutations. American Journal of Medical Genetics. 114:299–303.
[17] Laursen TM, Munk-Olsen T, Nordentoft M, Bo MP. (2007). A comparison of selected risk factors for unipolar depressive disorder, bipolar affective disorder, schizoaffective disorder, and schizophrenia from a Danish population-based cohort. Journal of Clinical Psychiatry. 68:1673–1681.
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Your DJ is a song by Nigerian premiere disc jockey and leader of TheCAP Music, DJ Spinall. The song is taken from his debut album, Iyanu. On the track, he features, DMW boss, Davido. Your DJ is the 4th record on the world class album. Check on it below and anticipate the full album drop on Okhype. Enjoy!


Thank You for Your Interest in Showing Your Support!
PAVE is a national non-profit education 501(c) 3 resource and support organization whose mission it is to raise public awareness of the crucial relationship between vision and achievement.
We depend on memberships and donations to fund our national effort to raise awareness and assist the thousands of parents and other individuals who contact PAVE each year.
However, there are several ways that you can help not only PAVE, but children with vision related learning difficulties everywhere.
You are invited to become part of the membership of PAVE by contacting the PAVE National Office for information and membership.
We will soon be making a membership application available on our site for your convenience. For now, please email info@pavevision.org for more information.
Starting a local PAVE Chapter in your community is a great way to raise awareness about the relationship between vision and achievement right in your own backyard.
The more schools and professionals in your area are acquainted with treatment options that can alleviate visual problems, the easier it is to raise awareness of legislators, insurance companies and school districts. If you are interested in forming a PAVE chapter in your community, please e-mail a request for a chapter inquiry packet by clicking here info@pavevision.org.
Monetary donations are also welcome. P.A.V.E. is a 501 (c)3 and your donation is tax deductible. For now, please email info@pavevision.org for more information.


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https://www.chron.com/business/press-releases/article/Ali-Pourvasei-of-LAD-Solutions-Listed-As-One-of-14090295.php
Ali Pourvasei of LAD Solutions Listed As One of 2019 Top SEO Consultants in the U.S. by FitSmallBusiness.com
LAD Solutions has announced that the Ali Pourvasei, one of the company's founders, has been named as one of 2019 Top SEO Consultants in the U.S. by FitSmallBusiness.com. Pourvasei has also been awarded special recognition in a report on the FitSmallBusiness.com website.
LOS ANGELES (PRWEB) July 12, 2019
LAD Solutions has announced that FitSmallBusiness.com, a leading digital resource for small businesses, has named Ali Pourvasei of LAD Solutions as one of 2019 Top SEO Consultants in the U.S.
FitSmallBusiness.com has published the ranking as a part of its SEO Services Reviews with Pourvasei listed under the Consultants rankings. Not only has FitSmallBusiness.com highlighted Pourvasei's career achievements, the article also provides a brief overview of the awards and recognition that his company has received.
The goal of the 2019 Top SEO Consultants list is to provide small business owners with a list of the most helpful SEO consultants from across the U.S. that have consistently exceeded client expectations. Pourvasei and LAD Solutions have excelled in delivering "outstanding expertise, service, and credentials in the SEO industry," according to FitSmallBusiness.
LAD Solutions has also achieved an A+ rating from the Better Business Bureau (BBB) and the company is listed as a premier Google Partner. In 2019 alone, the company has been awarded by Clutch as a Top SEO Company in Los Angeles, Top PPC Management Agency in Los Angeles, a Global Leader, and one of the Top 516 B2B Companies in California.
Ali Pourvasei, along with co-founders Lakshmi Kodali and David Barkhordari, started the company in 2009 after meeting at an SEO conference. Since then, the company has grown to become a nationally recognized firm serving clients throughout the U.S. In addition, LAD Solutions offers comprehensive SEO and PPC management to businesses of all sizes and in various industries.
Ali Pourvasei is a graduate of the University of California, San Diego with a degree in cognitive science and a minor in mathematics. He also holds an MBA from Pepperdine University's Graziadio Business School. Since his graduation in 2009, Pourvasei has obtained various industry certifications and Google Partners Specialist Challenge and is a certified Adwords Specialist. He is committed to ongoing education in order to directly assist his clients with their marketing strategies.
The annual report is available now on the FitSmallBusiness.com. To learn more about the consulting services that Ali Pourvasei provides, LAD Solutions has requested that interested parties request a quote at ladsolutions.com.
About LAD Solutions: LAD Solutions, based in Los Angeles, California, is a full service digital marketing firm. As a nationally recognized firm, LAD Solutions has helped clients develop their businesses from all regions of the U.S. Lakshmi Kodali, Ali Pourvasei, and David Barkhordari, the three founders of the company, started the company in 2009 after meeting at an SEO conference. Today, LAD Solutions works with clients from top brands in various industries. For more information about the services offered by LAD Solutions, go to ladsolutions.com.
For the original version on PRWeb visit: https://www.prweb.com/releases/ali_pourvasei_of_lad_solutions_listed_as_one_of_2019_top_seo_consultants_in_the_u_s_by_fitsmallbusiness_com/prweb16390624.htm


Rocky Seto joins Jason Romano of Sports Spectrum to discuss his faith journey, coming to know Jesus Christ at USC and his relationship with Seattle Seahawks coach Pete Carroll.
At the end of the day, what else matters? Think about what is or who defines success. It is about CHRIST!
Wherever you're called, the King Jesus himself has specifically placed you there, and know that it's exactly where you're supposed to be.
The life you live is the Super Bowl God is giving you. What is the Super Bowl God is giving you to live out?
Rocky returns to his alma mater and shares how he came to know Jesus on Trojan Vision, USC's nightly talk show.
Rocky shares his testimony, as well as his coaching experiences with the USC Trojans and Seattle Seahawks.
Rocky speaks to the participants of Kare Youth Football Camp.


Valentine Day Massacre, or Will Love Be in the Air?
So. Now we know. Feb 14 is the date that is the talk of the town and payments people in Europe in particular. No, spring hasn't softened us and made us all amorous. (Some perhaps, but not all!). I refer of course to the SEPA end date of Feb 2014, which was finally confirmed by European Parliament last month. The name SEPA end date is its self confusing – more than one corporate has asked me why it isn't called the SEPA start date as that may be more accurate. Volumes are still some way short of anything that be called significant market share. The latest indicators from the ECB show SCT take-up is at 24% and SDD at 0.4%. Even EMV at POS is only at 69%. The other comment from corporates I get is about the timing. The vote comes after they've already set, and in many cases, started, their budgets for this financial year. For those I've spoken too, this is resulting in not doing much, if at all anything, about it in the near future The supply side seems to have its own issues too. Many banks are ready for domestic scale SEPA volumes. But a number it would seem aren't. The solutions that were put in place for compliance when SEPA sending/receiving became mandatory are under review, or, in some cases being ripped out & replaced. This has a number of consequences. Firstly, for this to successfully happen, it requires both parties to be ready. There are a few elements in the final text that no corporate I've spoken to is aware of. They may not be issues but frankly they don't know. Specifically, the requirement to use ISO20022 to send payment files is the one that most are unaware of. One assumes that the bigger the corporate and/or the volume of payments they make, the more they are au fait with the regulations. The challenge then is that the smaller end of the market, particularly as there are over 23 million SMEs in Europe, and it sometimes feels, almost as many solution suppliers providing payment gateway/generation software to them! Secondly, any migration always happens at the last minute unless there is a clear, tangible benefit for moving early. That helps the banks that aren't ready in some ways in that it buys them time. But equally creates opportunities for those that are ready to aggressively target corporates now. The stage is being set for a very interesting and busy 2013, with a potentially very dramatic finale.


 Contact Us | Amirkabir Co.
Address: beside airport, Mahshahr- Sarbandar road, Mahshahr.
Address: Next to three-way, special zone, Assaluyeh.
Headquarter: First floor, Building no. 106 Lotfi St., Hafte-e-tir Square, Tehran, Iran.
چنانچه سوال یا درخواستی دارید می توانید با ما تماس بگیرید.


Daniel Negreanu blog is a favourite blog to poker gamblers worldwide in recent times. Every article published in this blog supports both new and existing users. As a beginner or an experienced poker player, you like to happily gamble throughout the leisure and earn as maximum as possible. It is the best suitable time to visit this website and explore every aspect of the poker gambling sector without any inconvenience. All users of this blog get more than expected assistance to be aware of the poker industry. They are keen to find out and use every opportunity towards the profitable poker gambling activities. Attention-grabbing gambling facilities not only catch the attention of gamblers, but also increase their interests to gamble. This is worthwhile to make clear doubts about poker sites and enhance expertise about poker strategies and offers on online. You will become one among satisfied poker players and be successful in this gambling sector.


text:
Q: Use Dictionaries for HP to my Enemies I´m building a tower defense game.I need to get "enemies" with 2 Health.
I've been trying:
foreach (float enemyKey in enemyKeysAAB)
{
    if (bullets[key].Intersects(enemyHitboxAAB[enemyKey]))
    {
        if (hpLEnemyAAB.Contains(enemyKey))
        {
            money += 20;
            tScore += 155;
            removeLEnemyAAB.Add(enemyKey);
            hpLEnemyAAB.Remove(enemyKey);
        }
        else if (bullets[key].Intersects(enemyHitboxAAB[enemyKey]))
        {
            removebullet.Add(key);
            hpLEnemyAAB.Add(enemyKey);
        }
    }
}

I'm using dictionaries to spawn and etc so [enemykey] in my code are each and every enemy.
I´m writing this in Game.cs cause we are not allowed to use classes and I don't know how to use one.
How can i use dictionaries to make enemies with HP?

A: You could make a enemyHP<float, int> dictionary I guess. where enemyHP[enemyKey] would give you that enemy's HP. And then you just check:
if (--enemyHP[enemyKey] < 1)
{
    // Dead
}

redpajama_set_name: RedPajamaStackExchange


The trail varies from a 4x2 and soft roader-friendly route, where the focus is on natural attraction, to a 4x4 route that is challenging in places and where low range, high ground clearance and care is definitely required. Mateke's 4x4 Trail runs through rocky terrain with steep inclines and river crossings that make for a good day's outing. Picnic spots between indigenous trees and halfway stopovers offer one the opportunity of a well deserved break. A permit fee of R150.00 is payable in order to enter the 4x4 trail. Accommodation is also available!


Exchange between Acting Education Minister Dalley and Liberal Education Critic Dale Kirby.
MR. KIRBY: Mr. Speaker, this government's indifference to the ongoing math performance crisis was demonstrated by the Acting Minister of Education last week. In response to questions about the math review announced in this year's Budget, the minister talked about funding for a math strategy that was announced in 2008 – seven years ago.
I will ask the minister again: What is the plan for this year? Exactly how much new funding has been set aside in Budget 2015 for your so-called math performance review?
MR. SPEAKER: The hon. the Acting Minister of Education and Early Childhood Development.
MR. DALLEY: Mr. Speaker, with respect to our math review, I have acknowledged in the House that there are lots of comments and concerns around the Province with math. Now I did comment that we will provide the funding through the department, through curriculum, through our Excellence in Math Strategy. I have also indicated if we need to find money, we will find it within the department because of the importance of the issue.
Now, Mr. Speaker, I did not say – I was a little bit misquoted in some of the media in that I am looking and acknowledging there are problems with the curriculum. What we need do, to be clear, is take a look at math as a whole. It is not just curriculum.
We need to look at how it is being delivered, how teachers are learning and how kids are learning, what is the role of parents, and what is the role of our post-secondary institutions. That is the conversation we want to have and I invite the member opposite to provide some suggestions.
MR. KIRBY: Mr. Speaker, the fact is government has long failed students by dismissing educators' concerns, by blaming teachers, and by not taking declining math scores seriously enough. In the end, it is children who suffer along with their parents who often feel helpless and just plain frustrated.
I ask the minister: If he serious about correcting government's failed record on mathematics, when will the math performance review announced well over a month ago start its work?
MR. DALLEY: Mr. Speaker, some of the latest results are indicating that we are seeing improvements in math performance, particularly at the academic and honours levels in the high schools. We know the importance of math in graduation.
We are seeing higher graduations rates, Mr. Speaker. We are seeing our dropout rates have improved dramatically. We are now seeing that more and more students are graduating from high school with an academic or honours completion, Mr. Speaker, an increase of over 10 per cent in the past ten years.
There are a lot of good things happening. Again, to acknowledge particularly in math, there is a brand new curriculum that has been implemented and a curriculum that is being used across the country in many provinces. We want to have a look at that, we want to invite people to have the conversation about math, and let's see if we cannot even improve the success that we have had so far.


text:
define(
    function(require) {
        var lib = require('../common/lib');
        var runtime = require('./runtime');

        /**
         * @class blend
         * @singleton
         */
        var blend = {};
        var controls = {};
        var isIOS = /iP(ad|hone|od)/.test(navigator.userAgent);

        //有些android手机只执行一次runtimeready
        document.addEventListener('runtimeready', function() {
           blend.readyState = true;
        },false);

        /**
         * 版本信息
         *
         * @property {String} version info
         */
        blend.version = '0.1';

        /**
         * 开放的Api接口entend到blend中
         *
         * @property {Object} Api接口
         */
        blend.api = {};

        /**
         * 注册控件到系统中
         *
         * @param {Control} control 控件实例
         * @return null
         */
        blend.register = function(control) {
            if(controls[control.id]){
                throw (control.type || "") + " New Object Already Exists";
            }else{
              controls[control.id] = control;
            }
        };

        /**
         * 注销控件
         *
         * @param {Control} control 控件实例
         * @return null
         */
        blend.cancel = function(control) {
            //console.log("reg: " + control.id);
            delete controls[control.id];
        };

        /**
         * 根据id获取实例
         *
         * @param {string} id 控件id
         * @return {Control}
         */
        blend.get = function(id) {
            return controls[id];
        };

        /**
         * runtime ready事件
         * @param {function} 触发函数
         */
        blend.ready = function(callback) {
            var handler = function() {
                outTimeFun && clearTimeout(outTimeFun);
                if (/complete|loaded|interactive/.test(document.readyState)) {
                    callback(blend);
                }else{
                    document.addEventListener('DOMContentLoaded', function() {
                        callback(blend);
                    }, false);
                }
                document.removeEventListener('runtimeready', handler);
            };
            if (blend.readyState || window.nuwa_runtime||window.lc_bridge) {
                handler();
            }else {
                var outTimeFun = setTimeout(handler, 200000);
                document.addEventListener('runtimeready', handler, false);
            }
        };

        /**
         * runtime layer接口
         * @todo remove
         * @property {Object}
         */
        blend.api.layer = runtime.layer;

        /**
         * runtime layerGroup接口
         * @todo remove
         * @property {Object} layerGroup
         */
        blend.api.layerGroup = runtime.layerGroup;

        /**
         * runtime core接口
         * @todo remove
         * @property {Object} core
         */
        blend.api.core = runtime.core;

        //把layer的事件触发绑定到blend上快捷使用

        ['on','off','fire','once','postMessage'].forEach(function(n,i){
            blend[n] = function(){
                runtime.layer[n].apply(runtime.layer,arguments);
            };
        });

        //把coreapi和layer上可直接操作的接口直接暴露给blend.api;
        lib.extend(blend,runtime.core);
        lib.extend(blend,{
            "layerStopRefresh":runtime.layer.stopPullRefresh,
            "layerBack":runtime.layer.back,
            "layerStopLoading":runtime.layer.stopLoading,
            "getLayerId":runtime.layer.getCurrentId,
            "layerSetPullRefresh":runtime.layer.setPullRefresh
        });

        //触发函数
        var mainCall = {};
        blend.start = blend.layerInit = function(id,callback){
            mainCall[id] = callback;
        };

        blend._lanch = function(id,dom){

            mainCall[id]&&mainCall[id].call(blend, dom);
        };

        //unload的时候注销所有组件;
        window.addEventListener("unload",function(e){
            for(var i in controls){
                controls[i].destroy&&controls[i].destroy();
            }
        });

        return blend;
    }
);

redpajama_set_name: RedPajamaGithub


I enjoyed my very first falafel on a family trip to Israel as a teenager. Served very spicy with mixed salad, in a flat bread, I still remember how delicious it was. As a chickpea fan, I naturally love them and I enjoy playing around with ingredients, flavours and colours. This beetroot falafel is not just pretty, it's quick and easy to make, healthy, packed with whole ingredients, ideal to make ahead and really filling. If you've never tried them, have a go!
Add the cooked beetroot, the sliced onion and chopped garlic to a baking tray, drizzle with olive oil and a sprinkle of ground cumin.
In the bowl of your food processor add the chickpeas, oats and parsley.
Add the baked beetroot, onions and garlic.
These falafels should be really soft and moist and should be handled carefully off the tray and onto a plate or container.
Serve immediately or cool and enjoy later in the week.
Falafels are a great way to produce delicious, nutrient dense tasty food for your vegetarian or vegan friends. Chickpeas provide you with plenty of plant based protein and good carbs.
Beetroot are very mild on taste, quite sweet actually, and offer so much heart healthy goodness.


text:
document.getElementById("release-0").className = "done";

// Release 1:
document.getElementById("release-1").style.display = "none";

// Release 2:
document.getElementsByTagName("h1")[0].innerHTML = "I complete release 2.";

// Release 3:
document.getElementById("release-3").style.backgroundColor = 955251;

// Release 4:
document.getElementsByClassName("release-4")[0].style.fontSize = "2em";

// Release 5:
var tmpl = document.getElementById("hidden");
document.body.appendChild(tmpl.content.cloneNode(true));

// Release 6:
// The releases are numbered differently in the assignment in this project file.

// Release 7: Reflect
// What did you learn about the DOM?
// What are some useful methods to use to manipulate the DOM?

// There are a few basic ways to access elements through the DOM.
	// 	getElementById
	// 	getElementsByTagName
	// 	getElementsByName
	// 	getElementsByClassName
	// 	querySelector
// We have the ability to change text (content and format),
// display options and even rearrange features.
// When accessing a single element that shares(could share?)
// tags with other elements, an index is needed to get to that
// specific place. Each call starts with "document".


This working paper by Jochen Clasen and Daniel Clegg, of the University of Edinburgh, together with Jon Kvist of the University of Southern Denmark, examines the nature of impact of the economic and political challenges engendered by the "Great Recession" on labour market policy reforms in Europe. The authors thus consider the question of whether the economic crisis has also brought a labour market policy reform crisis in its wake.
The three researchers studied six EU member states (the Czech Republic, Denmark, France, Germany, Spain and the United Kingdom) and observed different response patterns depending on the interpretative framing – or 'narrative' – of the crisis.
In the first phase of the crisis, all countries expanded their labour market policy efforts. As crisis deepened, however, there was a clear bifurcation between those states that stepped up structural reforms intended to reduce labour market segmentation and those that turned to a more aggressive agenda of retrenchment.
The authors conclude that their findings provide grounds for both optimism and pessimism. While observing no substantial evidence of a return to the "labour shedding" policies of the 1980s, they do identify a retrenchment of labour market policy in some states, including Denmark, the country that, in the 2000s, was so vaunted in this respect as a model for others to follow.


Before World War II, The Rev.Robert John Renison was appointed as Chaplain of the Royal Canadian Air Force in which capacity he was often called upon to perform duties for the Air Force in full uniform, despite being too old for active combat.
Bishop Renison's older son, Robert J. B., was a fighter pilot in the 405th Squadron of the Royal Air Force. His younger son, George, enlisted in the 48th Highlanders Regiment, serving in the United Kingdom, Germany, and Italy, where he was injured by a landmine. In May of 1940, Bob and his wing commander were shot down. In September 1940, his family finally received news that Bob was wounded and was a prisoner of war in Germany. He was held at Stalag Lufte III. In October 1944, the Red Cross lost track of the prisoners of Stalag Lufte III. Around early 1945, Bob hitched a lift to London, arriving sometime after Victory in Europe (V.E.) Day (May 8th). His brother, George, received word that Bob's camp had been overrun, and gained leave to go look for his brother in London. They met in a pub, where evidently they thought that a celebration was in order. They then sent a cable to their parents that Bob was safe.
In 1941, the Rt. Rev. Robert.J. Renison (who for over 20 years wrote a column for the Globe and Mail) was selected with eleven other journalists from Canada, to visit England as guests of the British Council. They left between September 16th and 18th from New York to England by "Pan American Clipper" and stayed for 3 weeks.
This is a black and white photograph of The Rt. Rev. Robert J. Renison with his first son, Robert J. B. after he enlisted in the Royal Air Force. Robert J. B. was a fighter pilot in the 405th Squadron of the Royal Air Force. He became a prisoner of war in 1940 and was released in 1945.
Before World War II, The Rev. Robert J. Renison was appointed as Chaplain of the Royal Canadian Air Force in which capacity he was often called upon to perform duties for the Air Force in full uniform, despite being too old for active combat. This is a black and white photograph of Bishop Renison wearing his Air Force uniform.
A photograph of Bishop Renison leading a ceremony in front of the North Bay cenotaph (celebrating the end of the war?) He is wearing a Royal Canadian Air Force Uniform. He is likely in North Bay due to his duties as Chaplain of the Royal Canadian Air Force.
In 1941, The Rev. Robert J. Renison (who for over 20 years wrote a column for the Globe and Mail) was selected with eleven other journalists from Canada, to visit England as guests of the British Council. Here they are photographed on the roof of their hotel on Sept. 30th, 1941.
Booklet of Sermons "Does God Care?"
Booklet of Sermons "Does God Care?" given to the parishioner's at St. Paul's Church, "Dedicated to the Men and Women of St. Paul's Church, Toronto, on Active Service." Rev. Robert J. Renison produced this booklet just before he left for Moosonee, (he left Toronto on January 1, 1944), and sent it to the men and women of the church on active service. He wrote also that he would read the 400 names on the St. Paul's Church "Roll of Honour" on New Year's Eve and remember them in prayer. The Roll of Honour was a list of active service men and women in the Second World War.
Rev. Robert John Renison with his first son, Robert J. B.
Cover of a Booklet of Sermons "Does God Care?"


Theology matters. Our God images are important. We all have them. Constructions in our minds of who, how and what God is like. We are all theologians, whether or not we think in those categories. These images form us, shape us, mold us, and even have the power to transform us, diminish us or constrict us. These physical and emotional abstractions drive our character and our character plays themselves out in the way we do life, in the way we do ministry, and in the way we live out our vocatio, our calling. They impinge on the way we raise our children, compete on the field, and spend our money; what websites we click on in our offices late at night; who we lay next to in bed; who we copulate with; and what we ingest into our bodies. It all matters, immensely so, these God or no-God images. These images of the holy or not-so-holy drive and fuel our virtue, and our virtue is what is seen as we live our lives in the politic public.
I suggest that our views of God have very real and practical implications in our everyday lives. They trespass in the way we discipline our children, in the way we care for ourselves, in the way we talk to other people, and in the way we care for creation. All too often, our God images are un-holy Trinities that are really no god at all. These images are made more in our own likeness than in the image. Our God is too small. Too white, too blond-haired and too blue-eyed. Too American, too powerful, too domesticated, too progressive, too conservative, too religious, too wealthy, too nice, too mainstream, too hip, too popular, too anything we desire, too misogynistic paternal, too emasculated feminine, too heterosexual, too homosexual, too much like Santa Claus, too cozy, too congenial, too perfect, too Hallmark sentimental, too friendly, too awful, too much of our own preferences, too modern, too static, too confined, too managed, too geometric, too vengeful, too anything goes, too stoic, too human, too much of a customer service representative for the way we think the world ought to be, too spiritual, too boring, too rule-oriented, too driven by four spiritual laws, too dualistic, too free, too narcissistic, too, too, too, too. I think that you are starting to get the idea.
What about a God who is mysterious and wonderful and ferocious for me, you, us, and the world? What about a God who is social, passionate, communal, missional, one in three and three in one, dancing, delightful, extravagant, on the margins, from the streets? What if?
Part Three explores what it means to edit, rescript and reconstruct our lives in a way that allows us to flourish in areté again. It is an exposé on the vices we so love and the virtues that we are called to live. The classic seven deadly sins are given contemporary names and I offer a trinity of virtues as the antidote for each of these vices. I offer compelling and honest stories from life in ministry, from the traumatic to the hilarious to the inspiring, in such a way that we are guided into areté again. I pull from theologians, philosophers and artists of our past and present to weave a narrative that strikes a balance between social justice and steadfast faith. I offer candid observations and reverently irreverent insights that will make you think differently about the Trinity, about salvation, about life, ministry and about grace.
We are all perfectly imperfect—this is why we need Jesus. It is why I need Jesus in my life. Christus Victor! It is my prayer that we would be honest with ourselves in all manner of theology, life and praxis. It is my prayer that we would be open to conversation, growth and dialogue about the vexations before us in a complex social situation. It is my prayer that we would sit with our internal angst holding loosely our position long enough to listen to people. Perhaps we may grow comfortable being uncomfortable and allow our current reformation to bring light from shadows. The Protestant reformation did not resolve itself over night and neither will we but we can commit to a journey together that moves beyond polarizations and sentimentalities. I am confident that after the shadows there is light. That is Good Friday to Easter Sunday, which is our faith, which is our hope, which is our story, which is our future!! God help us all!
At this point I could offer endorsements from good folks around the country who have read my book, but I will spare you the self-promotion. If you would like more information you can visit my website at tobinwilson.com. My website features a two minute book trailer video clip, a link to a KOMO 4 Television news interview that I did with Mary Nam and other printed and radio interviews. I would love to speak at any venue you might deem appropriate and of course would love for you to pick up a copy of my book. You can find the book on my website, Amazon, or any local bookseller can order a copy for you.


text:
Changing How Imagery Is Managed, Processed, and Distributed
Introducing Esri Image Server
Geospatial imagery is the fundamental base of most geographic information systems and mapping devices. The quantity of imagery available is growing exponentially from sources such as scanned aerial films, digital cameras, satellite imagery, scanned maps, and digital terrain models.
321 Pan Sharpened
NDVI
Panchromatic
Images with bands enhanced or algorithms applied.
A New Approach to Using Imagery
With these huge quantities of imagery come large problems in how to manage, process, and distribute it. The value of imagery is highest when a large number of users have access to the data quickly. With conventional solutions, image processing and distribution is difficult and time consuming, and end users have difficulty accessing and utilizing the imagery in their standard applications. Image Server is one component of the image solution, providing a new approach to storing, managing, processing, and distributing geoimagery.
Landsat images displayed in ArcGIS
Esri Image Server provides fast access and visualization of large quantities of file-based imagery, processed on the fly and on demand. Output imagery is displayed near instantly for a number of users working simultaneously without the requirement to first preprocess the data and load it into a DBMS.
Esri Image Server resolves bottlenecks in conventional image-processing workflows. It combines processing and distribution and enables the creation of new Web-based solutions that increase the usage and value of geospatial imagery.
This new product supports the leading GIS vendors' clients, including Esri ArcGIS Desktop, ERDAS IMAGINE, Intergraph GeoMedia, and MapInfo Professional, as well as Autodesk AutoCAD and Bentley MicroStation software. In addition, Image Server supports open standards such as Web Map Servers and HTML viewers.
Image Server is able to perform advanced image processing on the fly, such as image enhancement, orthorectification, pan sharpening, and complex image mosaicking. From the same set of base imagery the server can create and distribute multiple image products directly to ArcGIS or other mapping and GIS products.
Esri Image Server is able to perform advanced image processing on the fly.
Imagery can be processed by the server prior to being sent to the Web or client application. The imagery stored in Image Server can be preprocessed imagery (e.g., orthoimagery) or primary imagery (e.g., raw scanned frames or satellite imagery). Utilizing the server's processing power, multiple image products can be derived from a single data source, with different radiometric, geometric processing, and compression options. This removes data management problems associated with multiple preprocessed datasets and substantially reduces data storage requirements.
Esri Image Server is expected to be immediately popular within large mapping and imagery data management companies. There is also an opportunity for significant use within agencies and companies that manage and distribute large quantities of image data.
Key features of Esri Image Server include
Fast access to extensive imagery
Fully scalable enterprise client/server architecture
On-the-fly server-based image processing
Multiple imagery products from single source
Multiplatform GIS/CAD/Web client access
Direct access to multiple file formats and compression
Data security and access logging
Independence from third-party software or DBMS
Expandability through extensions and software development kits
Esri Image Server will operate on Windows servers and is expected to be available in the fourth quarter of 2005. For more information, visit www.esri.com/imageserver.


Panagia Axion Estin (Greek: Άξιον εστίν, Slavonic: Достóйно éсть, Dostóino yesť), or 'It is Truly Meet', the name given to the icon of the Virgin Mary before which, according to tradition, the hymn of Axion Estin was revealed.
During the ninth ode of the canon (the Magnificat), the disciple began to sing "My soul magnifies the Lord..." with the Irmos of St. Cosmas the Hymnographer (October 14), "More honorable than the Cherubim..." The stranger sang the next verse, "For He has regarded the low estate of His handmaiden..." Then he chanted something the disciple had never heard before, "It is truly meet to bless Thee, O Theotokos, ever-blessed and most pure, and the Mother of our God." Then he continued with, "More honorable than the Cherubim..."
The icon is commemorated by the Church on June 11 and July 13. The appearance of the Archangel Gabriel to a monk on Mt. Athos, and the revelation of the hymn "It Is Truly Meet..." is commemorated by the Church on June 11.
↑ Appearance of the Archangel Gabriel to a Monk on Mt. Athos, and the Revelation of the Hymn, "It Is Truly Meet..."
Miracles of the Icon of "Axion Estin"
This page was last edited on July 29, 2011, at 14:30.
This page has been accessed 29,125 times.


1933 - The party led by Adolf Hitler won the German election of March 1933. After winning through the democratic process, Hitler proceeded to concentrate power in his hands until he soon effectively had a dictatorship.
1934 - The Dionne quintuplets were born in May in Callander, Ontario. The wonder of five little girls being born in a single birth helped take people's minds off the grimness of the depression. Over three million people came to look at them and several books and films have since pointed out how they were exploited for the profit of others.
1935 - The "On-to-Ottawa" trek was begun in Vancouver by men from the relief camps of B.C. They jumped on freight trains, planning to make their way across the country to Ottawa, where they wanted to protest the government's use of relief camps or "slave camps" as they called them. Their leader was Arthur "Slim" Evans. When the trekkers reached Regina in June they were stopped by police and only Evans and a few others were allowed to go on to Ottawa where they met a stoney-faced Prime Minister R.B. Bennett. When Evans was later arrested, riots broke out in Regina. Some people feared the Communist organizers of the trek.
Relief camps were opened in 1932 and run by the Department of National Defence. Unemployed men were sent to the camps where they had to work building roads and digging ditches for 20 cents a day. Originally these camps were designed to hold 2000 men, but the numbers grew to 20,000 before this unpopular plan for dealing with unemployment was stopped in 1936.


This week on the Stogie Geeks we interview Jose Seijas and his son Enrique of Matilde Cigars. We talk about making the perfect stick and Cigar Aficionado Hall of Fame. All that and more on this weeks interview.


text:
Home Zurich
Give an example of a scientific theory Zurich
Scientific Management Theory Essay 480 Words 35 Scientific Concepts That Will Help You Understand We give names to everything in order to which leads to misunderstanding — for example, "theory
How can you use scientific theory in a sentence Answers
Scientific Revolutions (Stanford Encyclopedia of Philosophy). What is a scientific model? your theory or model for what happened. Give an example of a once-accepted model that was replaced by a revised model., A scientific theory is an attempt to explain some A theory that cannot be refuted or falsified is not a scientific theory. For example, science: pseudoscience:.
For a much more detailed discussion about writing scientific papers, Examples from the scientific literature that Revision of the theory of A scientific theory many of the equations in general and special relativity give and testable predictions to figure out which theory was right. For example,
Evolution: Evolution, theory in biology are by any standard an example of masterly scientific of the organism and give rise to The Criteria for Science and Scientific Theories Share Flipboard Email Print A scientific theory must help us understand the nature of our data.
The Criteria for Science and Scientific Theories Share Flipboard Email Print A scientific theory must help us understand the nature of our data. The Criteria for Science and Scientific Theories Share Flipboard Email Print A scientific theory must help us understand the nature of our data.
The main Objective of this paper is that the difference between Scientific and Non -Scientific Knowledge and Examine the boundary is there b... 7/09/2018В В· you'd be able to give an exact of what separates a good scientific theory examples of a speculative scientific theory that
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Subaru of Twin Falls is proud to introduce the newly redesigned 2017 Subaru Impreza. It should be available in our store in late 2016. This new impreza is a big deal for us because it will be the first Impreza Model to be completely built in America and will feature the new center stack which has been re imagined to focus on ease of use and design.
The newly revealed Subaru has gone through a complete redesign inside and out. From technology updates and a more spacious interior to its sleek new exterior body look, the 2017 Impreza will blow you away.
It is the first subaru to feature the new Subaru Global Platform and the first Impreza to be completely built in the United States.
With its standard Symmetrical All-Wheel Drive, it's everything you love about a Subaru in a striking new package.
The New Interior design focuses on refinement and comfort.
The 2017 5 door Impreza has been design with a larger rear hatch opening that offers more cargo room and versatility.
The Center stack has been remodeled to offer larger AC vents, and integrated touch screen STARLINK system. The design however maintains Subaru's simplicity for ease of use.
The seat design has been improved for comfort and support. High Quality material and stitching highlight the focus on quality and craftsmanship.
The new Subaru Impreza Sport is now available in both 4 or 5 door body style with unique interior and exterior features.
18 Inch Alloy wheels, 2 Liter Direct Injected Subaru Boxer engine delivering 152 HP, Sport suspension tuning and red stitching throughout the interior. The newly redesigned exterior offers a lower and wider stance, more aggressive headlights, strong character lines and LED taillights have been added to the body of the vehicle.
More Features of the new Impreza.
Starlink is now available with a new 8 Inch touchscreen, it also features Apple Car Play and android auto for a better user experience.
A 4.2 inch color LCD display has been mounted to the center stack for added information.
An updated Harman Kardon stereo system and keyless access Push start button are also available.
The redesigned cabin is now larger than ever and give you more legroom.
The Subaru Impreza is also the least expensive vehicle in the lineup with Eyesight, BlindSpot and rear cross traffic alert.
New for 2017 is reverse Automatic braking. It senses objects behind the vehicle as you are reversing and can bring the Impreza to a stop if necessary.


pre wedding Stephanie and Ryan's Glen Tanar pre-wedding catch up.
Had an awesome time walking round the grounds of Glen Tanar catching up with Stephanie and Ryan while we got a few pre-wedding photos. We took Dodie along for the fun too! Here are a few of my favourite photos.


text:
(2002) Scarlet's Walk
... read morePerhaps Tori Amos didn't intentionally whittle her audience down to merely the rabidly devoted ever since Boys for Pele, but it sure seemed that way with the deliberately abstract arrangements, double albums, and cover records. That devoted cult may be all that pay attention to Scarlet's Walk, her...
Amber Waves (Album Version)
A Sorta Fairytale (Album Version)
Wednesday (Album Version)
Strange (Album Version)
Carbon (Album Version)
Crazy (Album Version)
Wampum Prayer (Album Version)
Don't Make Me Come To Vegas (Album Version)
Sweet Sangria (Album Version)
Your Cloud (Album Version)
Pancake (Album Version)
I Can't See New York (Album Version)
Mrs. Jesus (Album Version)
Taxi Ride (Album Version)
Another Girl's Paradise (Album Version)
Scarlet's Walk (Album Version)
Virginia (Album Version)
Gold Dust (Album Version)
Released 10 September 2002, ℗ 2002 Sony Music Entertainment Inc.
Perhaps Tori Amos didn't intentionally whittle her audience down to merely the rabidly devoted ever since Boys for Pele, but it sure seemed that way with the deliberately abstract arrangements, double albums, and cover records. That devoted cult may be all that pay attention to Scarlet's Walk, her first album for Epic, but it marks a return to the sound and feel of Under the Pink and is her best album since then. Much was made at the time of release about its concept -- conceived as a journey through modern womanhood, when Tori herself journeyed through each state in the union -- but following the narrative is secondary to the feel of the music, which is warm, melodic, and welcoming, never feeling labored as so much of her last four albums often did. This doesn't mean it's an altogether easy listen: an intensive listen reveals layers of pain and an uneasiness murmuring underneath the surface, but it's delivered reassuringly, in croons and lush arrangements that nevertheless are filled with quirks, making it both comforting and provocative. Which, of course, is what Tori Amos delivered in her early years. If this isn't as startling as Little Earthquakes or majestic as Under the Pink, so be it. It's confident, alluring, and accomplished, luring listeners in instead of daring them to follow. And, frankly, it's a relief that she finally delivered another record like that. ~ Stephen Thomas Erlewine