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125th Anniversary of Foundation
Mother Teresa Casini
Vocation Journey
Pray for Priests
Foundress
Priest Retirement Homes
Cinquanta Club
Beatification of Maria Teresa Casini
A group of 41 pilgrims held the people of the Diocese of Youngstown in deep prayer during a special pilgrimage to Rome and to neighboring Frascati and Grottaferrata – two small towns twelve miles southeast of Rome.
Members of Oblate Sisters of the Sacred Heart of Jesus, their relatives, friends and group chaplains, Msgr. Michael Cariglio and Father Ray Thomas, left for Rome on October 27th, the birthday of Mother Casini.
Mother Casini, founded the Oblate Sisters on February 2, 1894 in Grottaferrata; she was beatified in Frascati in the cathedral where she was baptized on October 29, 1864, two days after her birth.
The Diocese of Youngstown played a key role in Blessed Teresa Casini's beatification because the miracle required for her beatification took place here.
In 2003, five-year-old Jacob Sebest of Campbell, Ohio drowned in a swimming pool and was diagnosed with irreversible brain damage. Two days later, on the feast of the Sacred Heart of Jesus, after intense prayer to the Sacred Heart of Jesus through the intercession of Mother Teresa Casini, young Jacob miraculously awoke from a medically induced coma without any signs of brain trauma. Today he is a healthy, vibrant 17-year-old and a senior at Ursuline High School.
For ten days the American pilgrims, including Jacob, his mother and brother (his father Joseph Sebest, Jr. who died in 2012 was with us in spirit), visited several holy places and prayed in a special way for each of you, your families and the intentions held deep within your hearts. The highlight of the pilgrimage centered on five special days.
On Thursday, October 29th, the day appointed by Pope Francis as Blessed Teresa Casini's feast day, the pilgrims prayed at the convent in Grottaferrata where Mother Teresa Casini first established her religious congregation and where she later died on April 3, 1937. We heard Mass in the chapel and prayed before the historical tabernacle that depicts her vision of the Pierced Heart of Jesus. We visited her bedroom and venerated her relic, which was the braid of hair that was cut off on the day she professed her vows and, unbeknown to her, was kept by those who sensed that one day she would be recognized for her great love end heroic virtues.
Then on Saturday, October 31st, our group joined five of Mother Teresa Casini's direct descendants, along with 3,000 other devotees in Frascati for the beatification Mass that was held in the piazza in front of the Cathedral of St. Peter the Apostle. The principal celebrant was Cardinal Angelo Amato, Prefect of the Congregation for the Causes of the Saints. Concelebrating with him were several bishops and priests. Among these were Bishop George Murry, S.J., Msgr. Michael Cariglio, Father Raymond Thomas, Father Shawn Conoboy, Father Christopher Cicero, and Father Joseph Tuscan, OFM, of the Youngstown Diocese.
Our hearts soared with joy when Jacob Sebest carried Mother Teresa's relic in procession, escorted by six Oblate Sisters and several young children strewing rose petals. I'm sure that Mother Teresa Casini, seeing this from heaven, was a bit put off by all the pomp and circumstance. On the other hand, I'm sure she was rejoicing in the fact that this was a grace-filled moment that increased our love for God and for our brothers and sisters in Christ.
On the next day, November 1st, the feast of All Saints, the Oblate Sisters, their relatives and friends gathered once again at St. Peter's Basilica in Rome for a Mass of Thanksgiving. The principal celebrant was Cardinal Angelo Comastri, the Archpriest for the Basilica of St. Peter and the Vicar General for the Vatican City State.
Immediately after Holy Mass we went outside in the piazza to pray the Sunday Angelus with Pope Francis. After the Angelus, Pope Francis announced: "Mother Teresa Casini, Foundress of the Oblate Sisters of the Sacred Heart of Jesus, was beatified yesterday in Frascati. She was a contemplative woman and missionary; she made her life an offering of prayer and concrete charity in support of priests. Let us thank the Lord for her witness!" You can imagine the cheers that bellowed forth from all of us gathered in her honor.
This triduum of Solemn Masses concluded on Monday, November 2nd, the feast of All Souls with our group of 41 pilgrims hearing Mass in the crypt of St. Peter's Basilica at the site of St. Peter's tomb. Bishop George Murry, S.J. was the principal celebrant as we gathered to pray in thanksgiving once again for the life and holiness of Blessed Mother Teresa Casini.
As a fitting conclusion to these extraordinary events, our USA pilgrims gathered in the piazza of St. Peter's one last time for a papal audience on Wednesday, November 4th.
The occasion was the beatification of Mother Maria Teresa Casini, foundress of the Oblate Sisters of the Sacred Heart of Jesus.
This triduum of Solemn Masses concluded on Monday, November 2nd, the feast of All Souls, with our group of 41 pilgrims hearing Mass in the crypt of St. Peter's Basilica at the site of St. Peter's tomb. Bishop George Murry, S.J. was the principal celebrant as we gathered to pray in thanksgiving once again for the life and holiness of Blessed Mother Teresa Casini. As a fitting conclusion to these extraordinary events, our USA pilgrims gathered in the piazza of St. Peter's one last time for a papal audience on Wednesday, November 4th.
After the papal audience, Jacob, his mother Marcy, Mother Arcangela Martino, General Superior of the Oblate Sisters, and Sister Amalia Iannelli, a General Counselor, were escorted to personally meet Pope Francis. They thanked the Holy Father for greeting them and were delighted to converse with him in English. Marcy gave Pope Francis a gift of a rosary containing the image of Blessed Maria Teresa Casini. She also asked him to pray for her beloved deceased husband.
The next day, November 5th, we parted for our return trip home. Our bodies were a bit tired, but our hearts and souls were as light as a feather. A few days after our return, one pilgrim e-mailed me. Among his musings, he made a statement that I believe reflected the sentiments of all who participated: "Sr. Joyce, as each day goes by, it continues to sink in that we experienced life-changing, as well as once-in-a-lifetime events. I'm so grateful that I decided to make this trip. I remain on an emotional and spiritual high, which is helping me as the realities of work and life return! Thank you."
I pray that the "realities of work and life" that you encounter everyday will be made a little lighter and filled with more joy as a result of the many prayers that we offered for each of you during our pilgrimage for the beatification of Blessed Maria Teresa Casini.
The Diocese of Youngstown celebrated Mother Casini's beatification on Sunday, May 22, 2016 at St. Columba Cathedral.
High School Lesson Plan
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Villa Maria Teresa
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Hubbard, OH 44425
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City Council OKs Resolution Urging Media to Curb 'Racist, Sexist Slurs'
CBS Los Angeles, March 22, 2012
The City Council has approved a resolution calling on local TV and radio stations to limit any "racist" and "sexist" comments on their broadcasts.
The City Council voted 13-2 to approve the resolution with a motion urging "the management of radio and television stations in Los Angeles to do everything in their power to ensure that their on-air hosts do not use and promote racist and sexist slurs over public airwaves in the City of Los Angeles".
Councilmen Joe Buscaino and Mitchell Englander cast the two opposing votes to the resolution, which was introduced on Mar. 7 by Councilwoman Jan Perry in response to a the controversy over recent comments by KFI 640 talk radio hosts John Kobylt and Ken Chiampou.
The duo had recently drawn criticism for referring to the late pop singer Whitney Houston as a "crack ho" in February in the wake of her untimely death.
Topics: Censorship
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Aulakh Jaipal S Dvm & Mpvm is a Veterinarians facility at 1445 Van Ness Avenue in Fresno, CA.
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A huge thank you to all of you who entered the giveaway, and to all of you who helped to spread the word!
"I adore the cover for this book, I love the contrast between the white and the red. So eye catching! Following your blog :)"
Congratulations! If you send us an email at yabluewater@gmail.com with your name and address, then we can make sure that your copy is sent to you as soon as it becomes available.
Last of all I would like to say a big thank you to Strange Chemistry, for letting me get involved with the cover reveal, and being generally awesome!! Thanks guys!


Massage Therapy Cary NC - Agape Touch - 4.2 out of 5 based on 2 ratings.
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Finite Life
The Words of Eric M. Stinton.
On January 26, 2016 By Eric In Mixed Martial Arts Like
The Prodigal Son Returns
"As an MMA writer, I try to be as objective and emotionally detached as possible. While I can proudly say I've checked my personal feelings at the keyboard — and many times gone about the sobering process of betraying them — the truth of the matter is that I'm still, at my core, a fan. So objectivity be damned: Quit playing games with my heart, B.J. Penn.
"The Prodigy" last week made his comeback official. In doing so, he sent fans everywhere jolts of excitement, anxiety and that feeling you get when you're called to the principal's office. I don't know how to process it all…"
Read more at Sherdog
Cyborg and the Post-Rousey World
"When Ronda Rousey lost at UFC 193 in November, it felt like a defining moment. The biggest star in the sport went supernova, sending shockwaves into the MMA universe that have just begun to register.
Before her fateful collision with Holly Holm's shin, Rousey put women's MMA on the map. She quickly rose to become the first legitimate female draw in MMA and then transcended that label to become one of the biggest draws in combat sports period. However, what we are now coming to understand is that Rousey did not only bring women's MMA to the forefront of public consciousness — she single-handedly held it there. The proof lies in the declining fan interest around Invicta Fighting Championships featherweight titleholder Cristiane "Cyborg" Justino…"
T.J. Dillashaw vs. Dominick Cruz Statistical Analysis
"Champion will fight former champion at UFC Fight Night Dillashaw vs. Cruz on Sunday at the TD Garden in Boston.
Former bantamweight champion Dominick Cruz has been on the shelf for the greater part of the last four years due to a long string of broken hands, torn knee ligaments and a torn groin. Cruz was the final World Extreme Cagefighting champion and the Ultimate Fighting Championship's inaugural titleholder at 135 pounds, but he vacated the title in January 2014 after more than two years of injury-induced inactivity. He briefly returned later that year and demolished Takeya Mizugaki, earning a title shot that would end up getting pushed back for another torn ACL. "The Dominator" has not lost a fight since dropping down from featherweight to bantamweight in 2008…"
On January 4, 2016 By Eric In Mixed Martial Arts Like
Sherdog.com's 2015 Fighter of the Year
"We should have seen it coming.
Rewind to this time last year. Of all the fighters coming off superlative years, of all the burgeoning and blazing stars of the sport, only one of them had the clairvoyance to know where he would end up by year's end: the man they call "Mystic Mac."
Entering 2015, McGregor was still plagued by questions and doubters. He had run roughshod over inferior foes, they said; the Ultimate Fighting Championship was handpicking opponents for him to look good against; he had yet to face a stud wrestler; his ground game was completely untested and unproven; he was being promoted because of his trash talk, not his skill. Such accusations brought comfort to the high school coach types who hated his cockiness, and they put staunch McGregorites in a defensive uproar. However, the man himself could not seem to be bothered by any of it…"
Low Hopes for McGregor's Redemption
Quality Reads from 2019
Some Things I Wrote in 2019
"To live is to war with trolls. To write is to sit in judgement on oneself." - Henrik Ibsen
Writing is hard, and it isn't terribly lucrative. If you enjoy my work, please consider making a donation. Your support goes a long way.
Copyright Eric M. Sintion | All Rights Reserved ©2015


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Las celebraciones por el 525 Aniversario del Descubrimiento de América fueron un conjunto de actuaciones, destinadas a conmemorar tanto la llegada de los españoles en 1492 al continente americano, como la importancia de este hecho en la historia universal. Para tal fin, en el año 2017, la Diputación de Huelva organizó una Comisión para la Conmemoración, con la finalidad de preparar, programar, organizar, coordinar y ejecutar las actividades destinadas a la celebración de dicho acontecimiento, la cual decidió denominar al evento con el nombre de 525 aniversario del encuentro entre dos mundos.

Las celebraciones proyectadas consistieron en actividades culturales, deportivas, académicas, turísticas, institucionales y de sensibilización ciudadana.

En los Lugares colombinos, las celebraciones locales se denominaron 525 Aniversario del Descubrimiento de América, y contempló multitud de actos conmemorativos, rememorando la participación clave de Palos de la Frontera, su monasterio de La Rábida y Moguer en el viaje descubridor.

En España

Comisión organizadora
La comisión organizadora estaba formada por el Ministerio de Educación, Cultura y Deporte, la Junta de Andalucía, la Diputación Provincial de Huelva, el Ayuntamiento de Moguer, El Ayuntamiento de Palos de la Frontera, El Ayuntamiento de Huelva, El Ayuntamiento de San Juan del Puerto, la Universidad de Huelva (UHU), la Universidad Internacional de Andalucía (UNIA), y la Universidad Nacional de Educación a Distancia (UNED). La disposición ministerial que denominó al acontecimiento como «525 Aniversario del Descubrimiento de América en Palos de la Frontera (Huelva)» lo calificó como "acontecimiento de excepcional interés público".

En su dossier de presentación se destacó el sentido de la iniciativa con la siguiente argumentación:

Objetivos
La iniciativa "525 aniversario del encuentro entre dos mundos" expresó el compromiso de las instituciones promotoras del evento por aunar, bajo una marca y objetivos comunes, el plan de actividades contempladas para conmemorar la efeméride. Entre sus objetivos se encontraban:
 Reafirmar la vocación americana como seña de identidad específica de la provincia de Huelva.
 Crear los cimientos que permitan desarrollar esa vinculación en el tiempo, para que sea percibida y asumida por la sociedad onubense como un valor de futuro.
 Fijar la marca América a nuestro territorio, y muy especialmente al de los Lugares Colombinos vinculados con el Encuentro.
 Identificar nuestro territorio como escaparate americano en 2017, a través de las plataformas de actividades diseñadas por las instituciones participantes.
 Promocionar los lugares históricos y desde ellos la provincia de Huelva en sus vertientes turísticas, económicas y culturales.

Véase también
 Celebración del IV Centenario del Descubrimiento de América
 Celebración del V Centenario del Descubrimiento de América
 Lugares colombinos
 Descubrimiento de América

Referencias

Bibliografía
 Dossier del 525 Aniversario. Dossier con explicativo de las conmemoraciones.

Enlaces externos
 525 encuentro de dos mundos – Web oficial del 525 encuentro de dos mundos.
 La Junta respalda la celebración del 525 Aniversario del Encuentro entre Dos Mundos en 2017. - Web de la Junta de Andalucía.
 El 525 Aniversario del Encuentro entre Dos Mundos refrendará la vocación americanista de la provincia de Huelva – Web Diputación de Huelva
  Convenio de colaboración para la creación de la Comisión Interadministrativa del acontecimiento de excepcional interés público "525 Aniversario del Descubrimiento de América" – Web oficial B.O.E.
 Programa actividades – Web oficial del 525 encuentro de dos mundos: Actividades programadas.

Historia de la provincia de Huelva
Historia de Moguer
Historia de Palos de la Frontera
España en 2017

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Baysox Swing And Miss In Opener
Bowie Baysox Staff | April 08, 2011, 06:43 AM	| 0 Comments
Bowie batters struck out 15 times as the Baysox lost to the Harrisburg Senators 5-0 Thursday in Harrisburg on Opening Night. The Baysox put runners on second base with no outs in each of the first two innings, but were unable to push either across.
In the first inning, leadoff hitter and center fielder Xavier Avery reached on a single and then stole second, but Senators starting pitcher Brad Meyers struck out the next three batters to leave Avery stranded. In the second inning, left fielder Robbie Widlansky hit a leadoff double, but again Meyers was able to retire the next three Baysox batters.
Baysox pitchers walked eight batters in the contest. Right-handed starting pitcher Chorye Spoone threw two scoreless innings before running into trouble in the third. Spoone walked Jonathan Tucker and Steve Lombardozzi to open the frame before striking out Derek Norris. Tyler Moore then hit a single that scored Tucker and advanced Lombardozzi to third.
Buck Coats followed with a single that scored Lombardozzi and advanced Tyler Moore to second. Spoone struck out Jesus Valdez for the second out of the inning, but then walked Bill Rhinehart to load the bases and Tim Pahuta to score Moore. Spoone struck out Josh Johnson to end the inning.
"The first two innings, I think I walked the one guy, but I was in the zone, Spoone said. "I'm not sure what happened going into the third. I guess I got a little quick, I didn't feel like myself. A couple of the guys told me that it looked like I was getting a little quick, getting a little ahead of myself."
Right-handed reliever Ryohei Tanaka took over for Spoone in the fourth inning. After Tucker flew out to right field, Lombardozzi reached first base on a fielding error by first baseman Joe Mahoney. Tanaka then walked Norris and a wild pitch during Moore's at bat advanced both runners. Moore would ground out, but not before Lombardozzi scored to make the game 4-0. Tanaka ended the inning by getting Coats to fly out to center field.
With two outs in the fifth, the Baysox started showing signs of life after a bunt single by shortstop Pedro Florimon and a base hit by right fielder Ronnie Welty put runners on first and second. However, the inning ended with no runs for the Baysox after Johnson, the shortstop, made a diving catch on a hit by Avery and got the force out at second.
"We had an opportunity to score and then the shortstop makes a nice play," said Baysox Manager Gary Kendall. "We could've maybe gotten on the board and stayed in the ballgame, but that didn't happen."
Right-handed pitcher Tim Bascom entered in the sixth inning and retired the side in order. Right-handed reliever Wynn Pelzer entered in the seventh and allowed a run on a double play by Coats that scored Norris who had reached base after being hit by a pitch.
Meyers threw five innings for the Senators and struck out nine while only allowing four hits. He was replaced by Henry Rodriguez, who is with the Senators on a Major League rehab assignment, in the sixth inning. Rodriguez compiled three more strikeouts and did not allow a hit in two innings of work.
[Meyers] kept the ball down, he changed speeds and he had effective breaking balls and changeups," Kendall said. "We were a little tardy on some fastballs early in the game and then when he started whipping out his breaking ball and changeup he got even tougher. In the middle of the game they brought in Rodriguez, on Major League Rehab, he had a quick arm and threw the ball in the mid 90s. He looks like he is ready to go back to where he belongs."
Coming back from shoulder surgery, Spoone threw 132.0 innings last year, but made his last start August 19, three weeks before the end of the season. This season, Spoone believes he is back to 100 percent and hopes to put in a full season of work for the first time since 2007.
"My goal is to throw at least 160 [innings]," Spoone said. "If I'm going to remain a starter the whole year, I'd like to hit the 160 mark by the end of the season. I'd be happy with that."
Opening Day was the first game of the season for everyone on the team, but for Welty, it was his first game at the Double-A level. Welty recorded one of just five hits by the Baysox, but admitted to feeling anxious in the opener and has some things he will work on improving in tomorrow's game.
"I will probably just attack the fastball a little earlier in the count," Welty said. "A lot of guys were letting good fastballs go by, including myself, so tomorrow I'm going to focus on hitting that first good fastball."
Kendall echoed the concerns that Opening Day jitters may have affected the offense and believes that better preparation for Friday's game will help the team put any worries behind them. The team's 15 strikeouts were the most since 17 Baysox struck out at Trenton on August 18.
"Hopefully it was a case of the Opening Day jitters," Kendall said. "Offensively, we have to be more prepared. We weren't really prepared early in the ball game; we were tardy on some pitches. From a pitching standpoint we can't walk as many guys as we did. When you look out on the board and you see us having five hits and them having four hits, you don't expect five runs on the board."
The Baysox open their first home stand at Prince George's Stadium Thursday, April 14, at 7:05 p.m. Friday, April 15, is Outdoorsman Night at the stadium, and Saturday is Betty White Tribute Night with postgame fireworks.
Tags: Baseball, Bowie, Bowie Baysox
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LRE Teams with Forsgren for EPC Water Master Plan - Leonard Rice Engineers, Inc.
This article is about El Paso County's new effort to create a Water Master Plan with the help of Forsgren Associates in conjunction with LRE. This exciting effort will culminate in late 2018 with a roadmap for the many water providers in the County to manage and develop their resources with an toward the future. We look forward to working with the County and Forsgren to achieve the goals for development of the plan.


Here's a confession I have no problem making: Not only did I not have high hopes for Trader Joe's Dark Chocolate Covered Ginger, I really didn't want to try it either. It's not that ginger and chocolate can't work together - they can - but...big crystallized ginger bites. We have a history. It's not good. But, here we go. Why? Check out our forthcoming podcast episode.
Thankfully, all my trepidation aside: I actually like these. They're not going to be my newest BSFF (best snack food friend), but I will be sad to see this now nearly-empty container go. It's got to be the chocolate - there's a good, thick coat of the typical high-quality TJ's dark chocolate indigenous to all their other candies - with an added firmness and crunch from the candy lacquer. The middles are that formerly formidable crystal chunks that I usually like in only small doses. That softer core adds a nice textural change up, while that chocolate tampers down that fierce ginger bite into something more palatable.
These Raisinet-sized bites do hit a certain balance. On one hand, when I need a chocolate fix, they deliver. But I can eat way too much chocolate. Thankfully, the ginger, while pairing well enough with the chocolate, still makes odd-enough bedfellows that make eating more thana small handful seem like not the best of ideas.
Both Sandy and I enjoy them, not sure who likes them more. I got a good laugh when she thought at first they were the new cocoa-covered coffee beans...oh, the face she made. Priceless. Anyways, it's $4.99 for the tub, and worth a try.
I LOVE anything ginger. I didn't love these. I like the thin sliced crystallized ginger but only if it's spicy, sometimes it's just too mild and like ginger flavored sugar but that seems to vary bag to bag.
The ginger chunks i'm not the biggest fan of the texture. Somehow this didn't work for me. And i love dark chocolate too. Was just an awkward pairing that just made me wish i was either eating some spicy ginger or some dark chocolate.
Why doesn't TJs sell pickled ginger...?
They recently changed the ingredients to contain butterfat...just so all those with dairy allergies are aware.


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Deer die at famous Japanese park after eating plastic bags
By Jessica Campisi - 07/10/19 07:41 AM EDT
Nine deer have died recently at a famous Japanese park after swallowing plastic bags, The Associated Press reports.
Nine of the 14 deer that have died since March had plastic in their stomachs, with masses of tangled plastic litter and snack packets recovered from their stomachs, according to the AP.
The heaviest mass removed from one of the bodies weighed close to 10 pounds, the news service notes.
With more than 1,000 deer, Nara Park reportedly allows tourists to feed the animals sugar-free crackers bought from local shops. And while those crackers don't come in plastic bags, some people carry them around while visiting the park.
The deer may have eaten the bags because they associated the plastic with food, a veterinarian told the AP.
Animals have continued to die in recent years after ingesting or getting caught in littered waste. A juvenile sperm whale washed ashore in Italy in May and was discovered to have a stomach full of plastic waste.
Last month, a sea turtle was found dead on the Florida coast after getting tangled in plastic waste and a fishing line. A mother bird in Florida was also seen feeding a chick a cigarette butt that was left behind on the beach.
Tags Japan Deer plastic bags


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Series of 6.1 earthquakes strike Greek Island of Crete, Felt in Israel
Dec 31, 2021 | 0 |
On Wednesday morning, a 6.1 magnitude earthquake shook the Greek Island of Crete. The quake was felt as far away as Israel. No injuries or damage were reported.
According to Israel 365 News, This comes after a series of three quakes (5.2, 5.4, 4.2) hit the island on Sunday. The quake was at a depth of 80 km (49.7 miles), the European Mediterranean Seismological Centre (EMSC) said.
On October 12, a powerful magnitude 6.3 earthquake rocked Crete, two weeks after another tremor on the island killed a man and damaged hundreds of buildings. The island of Crete is referred to in the Bible as Caphtor (Amos 9:7, Jeremiah 47:4).
Though no catastrophic earthquake has been recorded in Crete, a cataclysmic volcanic blast that took place at approximately 1627 BCE and 1600 BCE in the nearby island of Thera was one of the largest volcanic eruptions in the last 4,000 years.
According to Express, An earthquake of magnitude 5.7 struck Crete, Greece, on Wednesday, the country's Geodynamic Institute said. There were no immediate reports of injuries or damage. Egyptian authorities reported the quake was felt in some of the country's cities.
Akis Tselentis, director of the Geodynamic Institute who was in Crete, told Greece's Skai TV: "I felt it." Thankfully it was in the sea. The area is already burdened (with earlier tremors) and if it were inland there could have been damage," he said.


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Home Health & Medicine Genetics
Evolution: What is it? How does it work?
Nature has a way of pressuring creatures to adapt to their environments over generations.
by Zoe Gordon
in Genetics, News, Science
This is an odd start, but before we get into complicated things I want to talk about something near and dear to my heart—corn. Once upon a time, the corn we know and love (at least I do), used to be something called teosinte, a small green plant that doesn't look anywhere near as appetizing. It is hard to believe, I know, but something very interesting happened. In the area that is now Mexico, this plant was identified as having potential as a food crop, so farmers began intentionally growing it. Being good farmers, they thought that maybe if they kept the seeds of the biggest ones and kept planting those they would get more food out of it. As it turns out, they were right. After ten thousand years of only planting the ones that produced the biggest kernels, we ended up with maize as we know it today. It's bizarre but entirely true and it happened through a process we call artificial selection.
In nature similar, very strange changes can happen to species over time given enough pressure by the environment around them. Evolutionary biology is essentially the study of how organisms have changed over time to develop into new species. The topic is a bit contentious, as we all know, but there are also many common misconceptions about exactly how this process works. Thinking about it as a whole is difficult, with many points where it is easy to get hung up and confused. So, instead of looking at the big strange picture, we should start with a closer look at the little parts that make up the concept. As we move into this article, remember that, ultimately, every species needs to survive and reproduce because that's how species continue to exist. With that said, let us take a look!
Credit: Pixabay.
Let us consider two individuals, Tom and Jack. Tom is long-limbed, athletic, lightweight, and doesn't have much body hair. Jack is shorter, has a fair amount of hair, and a larger, higher-fat build. If you put both of these men in a forest, it is likely that Tom will have a bit of an advantage with traversing, climbing, et cetera. However, take the same pair and put them in a windy tundra and Jack will likely do a lot better in the harsh weather.
Every environment poses its own unique challenges. If you live in an area that has a lot of water, you will do a lot better if you can swim. If you live in an area that has a lot of plants and cover, predators are less likely to see you if you're small and green. These factors contribute to something we call fitness which is a measure of how well you are built to survive and how likely you are to reproduce. In some ways, it's a bit like physical fitness in humans. And, similarly, this fitness affects more than just your looks.
Genetics plays a huge role in this, and your genes (genotype) are expressed through your outward characteristics, called your phenotype. Small brown lizards living in a forest are displaying ('expressing') genes that give them the small and brown phenotype, and maybe even more that tell them to like staying on surfaces that match their color. Which brings us to the next main idea, a process called natural selection.
Natural selection looks at the differences in the likelihood of survival and reproduction based on a species' phenotype. Ultimately, in nature, creatures that have genes that result in fit phenotypes will survive and reproduce. This concept is where the term "survival of the fittest" comes from. The survivors live to have offspring and so genes in that population will, therefore, start leaning towards that fitter survivor genotype. Let us use an example.
Imagine that in a grassland there is a population of mostly large, green grasshoppers. They are doing well here because nature provides a lot of cover. This season, though, there isn't much rain and the grassland starts turning brown and sparse. This means that the larger, brighter grasshoppers become much easier to see by predators and many of them get eaten. So, the next generation of grasshoppers ends up being mostly smaller and perhaps a bit less green, because the ones that best survived the change in the grasslands were the ones that were harder to see.
This is natural selection. Those built to survive in an environment will live long enough to have offspring, changing the gene variety in the next generation. The same process happens with plants, fungi, and microorganisms. An important thing to note here, though, is that this is only possible because a healthy population has a wide range of genes to choose from. Not all organisms of a species will be the same size or the same color or have the same features.
Charles Darwin is considered the father of modern evolutionary biology. He developed his theory of natural selection by observing the variations among the species of the Galapagos Islands. He was best known for his study of birds, which all occupied different niches on these far islands but bore obvious resemblances to mainland species. Image credits: John Gould.
Over a long period of time and given a lot of pressure, a population of organisms can change in significant ways. The reason we are now having an antibiotic crisis is that, after many years of exposing bacteria to chemicals designed to kill them, the ones that had the gene quirks allowing them to survive are the ones which were able to multiply. So now we have a large number of antibiotic-resistant bacteria to contend with which have whole sections of DNA that exist only to counteract these drugs—but that, of course, raises a question. If they didn't have these genes before, why do they have them now?
Mutant Power
Mutation is a major factor influencing the process of evolution. Every so often, when cells are dividing, the mechanisms that copy bits of genetic data make a mistake. While it can often result in problems, it sometimes creates just what an organism needs to survive. One reason why HIV has been so hard to cure is that its reproduction process is unstable and prone to genetic errors. What this means is that the medication will work on most viral particles, but not all of them. The virus is, therefore, constantly evolving and the 'error', mutant forms that help it survive persist due to natural selection.
Some mutations are overtly harmful, like mutations in hemoglobin genes that cause sickle cell disease, where red blood cells curve into a "sickle" shape. The mutation makes the cells less efficient oxygen carriers and more fragile, and sometimes they cause painful blockages and organ damage. However, these mutations continue to persist because if a person is only a carrier, having received the variant gene from only one parent, it has a protective effect against malaria—a common disease in the parts of Africa where sickle cell is most prevalent. The fragility of the cell due to the hemoglobin structure means the cell will often rupture before the parasite can reproduce. But, since the remainder of their hemoglobin is normal, they don't experience most of the severe effects seen in persons with the full form of the disease. The carrier phenotype is, therefore, fit. Natural selection is a strange process indeed.
So we have looked at mutation, natural selection, and fitness. We have looked at bacteria and viruses and how these factors have made them survive and evolve on a smaller faster scale. Now, how does that translate to bigger more complex things?
Imagine that there is a ground-dwelling species of mammal that lives in a forest. Many of them are competing for the same food sources. A few of them, have started climbing in the hopes of finding another food source. A mutation comes which makes one offspring's claws curve a bit more, causing that individual to be better at climbing. It survives to reproduce. A few generations down the line, all its descendants may have these curved claws. Somewhere along the line, a descendant is born with unusually long limbs which makes it better at both climbing and jumping, this individual's offspring may well, do better than others—and so on. These minor changes can add up over time, just like the biggest teosinte kernels being intentionally planted. In nature, however, it takes far longer than a neat ten thousand years to produce something as different as maize.
Let this mammal group adapt for many thousands of years with natural selection favoring climbing habits and hunting in trees. At the end of that time if you were to take one of these climbing adapted creatures and put them alongside the ground dwellers they would look very different. They may have a different body form, make different sounds, have eyes that are adapted to seeing at a distance, and so on. And, because of the amount of mutation and genetic changes that brought them to this point, any offspring born of a mix of these two creatures would be sterile like a liger or mule. Just like that, you now have two different species. This also speaks to a common misconception, the idea that if one organism advanced from another, the first one should be gone. That simply isn't how the process works.
In nature, creatures will exist side by side as one group remains the same and others experience changes due to environmental pressure. It is strange, and hard to fully appreciate, but we have a bit of evidence that can follow the trail. Think even of the liger I just mentioned, the mere fact that a lion and tiger—two distinct species from two different regions—can produce offspring means that their genotypes must be similar enough to make an embryo viable. We interpret this to mean that these big cats must have some ancestry in common.
What Do We Know?
Though it happens over a very long period of time in creatures that take longer to reproduce than bacteria or viruses, there are a few ways we can observe that evolution is an acting process. If an organism has advanced from one form to another, it stands to reason that there had to be some forms in between. Well, though we don't always have all the bits of the puzzle, the fossils we find often help us fill these gaps. For example, between dinosaurs and birds we have found species of feathered, winged dinosaurs like Archaeopteryx.
There are also several odd cases in nature of organisms growing parts they have no need for. Some snake species and legless lizards retain a pelvic girdle with no real function, dolphin embryos in development still start to grow hind limb buds that retract after a time, and many cave dwelling or burrowing species retain non-functioning eyes. The fact that the genetic machinery required to make these structures happen exists, presents as evidence that these genes had a purpose at some point in the organism's history.
There are other factors to consider as well. Genetic evidence frequently shows fairly small differences between one species and another of a similar type that cannot reproduce with each other. In fact, genetic evidence shows that a large variety of organisms have a surprising number of genes in common—whales, humans, bats, and cats all have the same bones making up their forelimbs. But, this gets into very complex discussion and murky waters. This article really just serves to give a background of a concept. Take the information here, interpret and think about it as you will and, of course, there are many other great sources of information on the topic out there. Whether evolution on a larger scale makes sense to you or not, hopefully we can at least agree that these smaller processes of change are things we can observe. By now, I hope, the idea of what evolution is and how it works is at least a little bit clearer.
Tags: evolutionnatural selection
Zoe Gordon


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text:
KS - 82 Min. Outage; Failed Transformer
Outage pulls plug on city businesses By Brady McCombs, Journal-World Writer
A failed transformer led to an 82-minute power outage Friday evening in northwest Lawrence and Lecompton.
Nearly 3,000 customers were without power from 8 p.m. to 9:22 p.m., KPL spokesman Mark Schreiber said. A transformer at Baldwin Creek Substation in northwest Lawrence failed, bringing on the outage, he said. The failure was not caused by rain or lightning.
"They had to go out and identify the problem at the substation," Schreiber said. "It's a pretty sizable outage, but we were able to reroute the power and get them back on."
In Lawrence, the outage stretched north to Peterson Road, east to Monterey Way, south to 15th Street and west to the city limits.
Pizza Hut, Blockbuster Video, Dillons, Hy-Vee, Arby's and J.B. Stout's Grille and Bar were among businesses unable to operate during the outage.
Jim Lund, general manager of J.B. Stout's, 721 Wakarusa Drive, said his restaurant went pitch dark with a full house and a 45-minute waiting list.
He estimated actual lost business and potential business on what normally is one of the restaurant's busiest nights at $5,000 or more.
It wasn't a good day for Lund. First, he set off the burglar alarms on the restaurant about 7:30 a.m., necessitating a visit by Lawrence Police. Then, he discovered that 15 empty kegs had been stolen from the restaurant.
"I've had a fun day," he dead-panned.
Lund said that during the outage his customers were orderly and polite.
Sarah Burkett, shift manager at Pizza Hut, 4651 W. Sixth, said the business lost 20 pizzas and had to cancel 10 deliveries. She said between 8 p.m. and 9 p.m. Friday usually is a prime delivery time. She estimated more than $500 in lost business.
"It was our busiest Friday in a while when the power went out," another shift manager, Pete Gaines, said.
At Dillons, 3000 W. Sixth, employees were forced to move all frozen goods to walk-in freezers in the back of the store.
"There were a fair amount of people here, but no one freaked out or anything, which is good," employee Chris Dull said, adding, "Can you say 'lost business?'"
Schreiber said KPL will investigate the failed transformer.
"We will keep the power rerouted until we make sure everything is back up to speed at the substation," Schreiber said.
http://www.ljworld.com/section/citynews/story/19092
-- (Dee360Degree@aol.com), July 29, 2000


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text:
Wed 23 May 1877
YOUNG MEN'S CHRISTIAN ASSOCIATION.
The sixth anniversary demonstration in connexion with the Young Men's Christian Association was held at the Town-hall last night. Notwithstanding the somewhat
Wed 23 May 1877 - The Argus (Melbourne, Vic. : 1848 - 1957)
Page 6 - YOUNG MEN'S CHRISTIAN ASSOCIATION.
YOUNG MEN'S CHRISTIAN
ASS0C1ATJ0A.
The Bixth anniversary demonstration in
connexion with the Young Men's Christian
Association was held at the Town-hall last
night. Notwithstanding the somewhat un-
favourable state of the weather, the affair
was extremely successful in all respects. The
proceedings commenced with a tea meeting,
at which about COO persons were present. A
public meeting and concert were then held.
The Rev. Dr. Cairns presided, and there was
an enormous attendance, the hall being
crowded in every part. The chairman
delivered a brief address, in which he
pointed out the great good which was being
done by societies such as that the anniver-
sary of which they were celebrating, and he
urged the advantage of all sections of Chris-
tians endeavouring to render the association
still more useful in the future than it had
been in the past. The Bixth annual report
of the association, which was read by the
secretary, was of an encouraging character.
The number of members and subscribers on
the roll at the beginning of last year was S73,
wbile during the year 135 new members had
been added, 13G resigned, and six died,
making the present Btrength of the association
SGI, or a decrease of 12 during the year. This de-
crease, however, the secretary explained, was
principally owing to the want of accommoda-
tion for members, and as the association had
now obtained a new building, it could be
expected that the number of members would
be very largely increased before the end of
the present year. The employment and
boarding-house registries had been success-
fully carried on during the year, and had
proved of great benefit. The library now
contained 1,800 volumes; the lectures de-
livered under the auspices of the asso
ciation had been greatly appreciated,
and the literary and debating society«
had been fairly attended. The site on
which the new building was being erected
bad been purchased for £4,300, and the
tender of Mr. W. Little at £2,145 waa accepted
for the building of the new hall. Donations
to the society bad been promised to the
amount of £2,200, in addition to subscrip-
tions of £5 each from a number of the mem-
bers, making in all about £3,300, of which
sum upwards of £2,200 had been collected.
The committee urged the necessity of
continued effort in the matter of collecting
donations, &c as only about half the
cost of tbe land, building, and furniture
in connexion with the new hall had been
raised. Satisfactory progress was reported
in regard to tbe mission and devotion work,
and the report concluded by expressing a
hope that now the association was entering
upon a new era its sphere of usefulness
would be still further extended. The report
waB received with much applause, and was
unanimously adopted. The concert, which
was given solely by the pupils of the Asylum
and School for the Blind (under the
direction of Mr. F. W. Harmer, teacher of
music and einging at the asylum),
was extremely enjoyable, some of the
Sianofoite selections (especially one by
lies Constance Heine, a blind girl only 14
years of sge) being very excellently rendered.
The part-songs and glees were also very well
given, and evinced the careful tuition of the
teacher. During the course of the evening
addresses were delivered by different clergy,
men present, and the proceedings concluded
witb the singing of the beautiful hymn
" Abide with me,''
YOUNG MEN'S CHRISTIAN ASSOCIATION. (1877, May 23). The Argus (Melbourne, Vic. : 1848 - 1957), p. 6. Retrieved January 20, 2021, from http://nla.gov.au/nla.news-article5923025
"YOUNG MEN'S CHRISTIAN ASSOCIATION." The Argus (Melbourne, Vic. : 1848 - 1957) 23 May 1877: 6. Web. 20 Jan 2021 <http://nla.gov.au/nla.news-article5923025>.
1877 'YOUNG MEN'S CHRISTIAN ASSOCIATION.', The Argus (Melbourne, Vic. : 1848 - 1957), 23 May, p. 6. , viewed 20 Jan 2021, http://nla.gov.au/nla.news-article5923025
{{cite news |url=http://nla.gov.au/nla.news-article5923025 |title=YOUNG MEN'S CHRISTIAN ASSOCIATION. |newspaper=[[The Argus (Melbourne)]] |issue=9,652 |location=Victoria, Australia |date=23 May 1877 |accessdate=20 January 2021 |page=6 |via=National Library of Australia}}
The Argus (Melbourne, Vic. : 1848 - 1957), Wed 23 May 1877, Page 6 - YOUNG MEN'S CHRISTIAN ASSOCIATION.


text:
Published online: 22nd February, 2008
■ Pyrazolo[1,5-a][1,3,5]triazines(5-Aza-9-deazapurines): Synthesis and Biological Activity
Anton V. Dolzhenko, Anna V. Dolzhenko, and Wai-Keung Chui*
*Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
The present review gives an account on the synthetic routes to pyrazolo[1,5-a][1,3,5]triazine system, which is an isostere of purine, and polyfused systems bearing this heterocyclic core. Data concerning biological activity of compounds with pyrazolo[1,5-a][1,3,5]triazine skeleton are also discussed.
■ Arylhydrazononitriles as Building Blocks in Heterocyclic Synthesis: Synthesis of New Benzothiazolyl-1,2,3-triazole Amines and -1,2,3-triazol-4-yl-1,3,4-thiadiazol-5-ylamines
Khadija Omar Badahdah
*Chemistry Department, Faculty of Science, King Abdul Aziz University, Jeddah, Saudi Arabia
Benzothiazole-2-ylacetonitriles 6a-b and 5-benzoylamino-1,3,4-thiadiazol-2-ylacetonitrile 6c-d coupled with aromatic diazonium salts to yield arylhydrazones 7a-d. Compound 7a-d reacted with hydroxylamine hydrochloride in ethanolic sodium acetate to yield the corresponding amidoximes 8a-d. Compounds 8a-d cyclized readily into the 1,2,3-triazole derivatives 9a-d upon reflux in ethanolic DMF in the presence of anhydrous sodium acetate.
■ Synthesis of Pyrrolo[2,3-d]pyrimidine Analogues of the Potent Antitumor Agent N-{4-[3-(2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)propyl]benzoyl}-L- glutamic Acid (TNP-351)
Gaojun Zhu, Zenglu Liu, Yun Xu, and Zhenmin Mao*
*School of Pharmacy, Shanghai Jiaotong University, Shanghai 200240, PR China
Two three-atom-bridged analogues of TNP-351, N-(4-{[(2-amino- 4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-ylmethyl)amino]methyl}- benzoyl)-L-glutamic acid (4) and N-(4-{[(2,4-diamino-7H-pyrrolo[2,3-d]- pyrimidin-5-ylmethyl)amino]methyl}benzoyl)-L-glutamic acid (5) were synthesized as anticancer agents, and their biological activities were evaluated.
Published online: 7th March, 2008
■ Medicinal Foodstuffs. XXXIII. Gastroprotective Principles from Boesenbergia rotunda (Zingiberaceae) - Absolute Stereostructures of Diels-Alder Type Addition Prenylchalcones
Masayuki Yoshikawa,* Toshio Morikawa, Kanako Funakoshi, Momotaro Ochi, Yutana Pongpiriyadacha, and Hisashi Matsuda
The methanolic extract from the rhizomes of Boesenbergia rotunda (Zingiberaceae) was found to exhibit potent inhibitory activities on ethanol- or indomethacin-induced gastric mucosal lesions in rats. Through the bioassay-guided separation, six new optically active Diels-Alder type addition prenylcalcones, (+)-panduratin A (1a), (-)-panduratin A (1b), (+)-4-hydroxypanduratin A (2a), (-)-4-hydroxypanduratin A (2b), (+)-isopanduratin A (3a), and (-)-isopanduratin A (3b) were isolated together with 12 known compounds [(4-14) and geraniol]. The absolute stereostrucutures of six new compounds were elucidated on the basis of physicochemical evidence including CD spectra. Among them, the enantiomeric mixtures of panduratin A (1a, 1b) and 4-hydroxypanduratin A (2a, 2b), and pinocembrin (4) showed gastroprotective effects on ethanol- or indomethacin-induced gastric mucosal in rats.
■ Solvent-Free Synthesis of 2-(1H-Benzimidazol-1-ylmethyl)-4-substituted 1-Hydroxyaryl by the Two Component Mannich Reaction between 6H,13H-5:12,7:14-Dimethanedibenzo-[d,i][1,3,6,8]tetraazecine (DMDBTA) and Phenols
Augusto Rivera,* Miguel Angel Navarro, and Jaime Ríos-Motta
*Departamento de Química, Universidad Nacional de Colombia, Ciudad Universitaria, Carrera. 30 # 45-03, Bogotá, D.C., Colombia
A new series of Mannich bases (7a-e) were synthesized with good yields, in a single pot by a two component Mannich-type reaction under solvent-free conditions from 6H,13H-5:12,7:14-dimethanedibenzo[d,i][1,3,6,8]- tetraazecine (DMDBTA 1) and phenols (6a-e) at 150 °C. The mechanism of formation of those Mannich bases and their subsequent thermal decomposition into 1H-benzimidazole (8) and respective ortho-methylated phenols (9a-f) by an o-quinone-methide intermediate are also discussed.
■ Enantioselective Synthesis of Piperidine Diamine Derivatives as Novel fXa Inhibitors
Akiyoshi Mochizuki,* Hiroyuki Naito, Yumi Nakamoto, Kouichi Uoto, and Toshiharu Ohta
*Medicinal Chemistry Research Laboratory I, Daiichi Sankyo Co., Ltd, 1-2-58, Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan
Previously, we reported that racemic cis-piperidine diamine derivatives (±)-1 showed high anti-fXa, anticoagulation activity and oral activities. To confirm the active enantiomer, (3R,4S)-piperidine diamine derivatives (-)-1A and (-)-1B were synthesized enantioselectively from Boc-D-serine. These synthetic routes and intermediates could be utilized for the optimization of these derivatives. From the activities of (-)-1A and (-)-1B, (3R,4S)-isomer was confirmed to be the active enantiomer.
■ Simple and Convenient Synthesis of 2,3,4,5-Tetrahydro-1,5-dioxopyrrolo[1,2-a]quinazoline- 3a(1H)-carboxylic Acids in Multi-Gram Scale
Rustam T. Iminov, Anton V. Tverdokhlebov,* Andrey A. Tolmachev, Yulian M. Volovenko, Alexander N. Kostyuk, Alexander N. Chernega, and Eduard B. Rusanov
*Enamine Ltd., Alexandra Matrosova str. 23, 01103, Kiev, Ukraine
The title compounds were prepared in 70-100 grams scale by reaction of 2-amino-N-alkyl(aryl)benzamides with 2-oxoglutaric acid. Their structure was proved unambiguously by X-ray crystallographic study.
■ A New Route for the Synthesis of Linezolid Mimetic 3,4-Disubstituted Oxazolidin-2-one Derivatives
Fumiko Fujisaki, Nobuhiro Abe, and Kunihiro Sumoto*
*Faculty of Pharmaceutical Sciences, Fukuoka University; Nanakuma, Jonan-Ku, Fukuoka 814-0180, Japan
New oxazolidin-2-ones (3), which mimic the clinically useful antibacterial agent (1) (Linezolid) were prepared by using a cyclization procedure with diethyl carbonate from aminoalcohol (7) starting with DL-serine methyl ester hydrochloride (4) and aromatic carboxylic acid derivatives (5).
■ Versatile Three Component Coupling for the Synthesis of Pyrazolopyridines and Other Pyrido Fused Systems
Carmen Almansa,* Marina Virgili, Elena Carceller, and Pedro Grima-Poveda
*Innovation and Drug Discovery, Palau Pharma S. A. (Grupo Uriach). Av. Camí Reial, 51-57, E-08184, Palau-Solità i Plegamans, Spain
A new unexpected reaction of 1-(4-fluorophenyl)-2-(4-pyridyl)ethanone 2 with 3-aminopyrazole, involving loss of a 4-pyridylmethyl group, afforded 4,6-bis(4-fluorophenyl)-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine 1 in good yields. Investigation of the features of this cyclization led to the development of a new three component coupling for the synthesis of pyrazolo[3,4-b]pyridines, from a ketone, an aldehyde and a 3-aminopyrazole in the presence of acid catalysis and a protic solvent. The study of the scope of this reaction showed its remarkable versatility and its usefulness in the preparation of other bicyclic systems, such as thieno[3,2-b]pyridines, pyrrolo[3,2-b]pyridines, imidazo[4,5-b]pyridines, furo[2,3-b]pyridines, isoxazolo[5,4-b]pyridines and, isothiazolo[5,4-b]pyridines. The three component nature of this reaction makes it suitable for the preparation of combinatorial libraries since scaffold decoration can be easily achieved in one step.
■ Ring Current Models of Porphyrin and Conformational Analysis of the Dicarboxylate Complex of SNIV Porphyrin
Hajime Iwamoto* and Yoshimasa Fukazawa*
*Department of Chemistry, Graduate School of Science, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8526, Japan
Several models for the porphyrin ring current effect are constructed based on a classical line current approximation and their performances in reproducing the observed induced shifts of ligand protons in SnIV(porphyrin) dicarboxylate complexes are compared. A new model is selected and it is found that the diamagnetic ring current running on the inner 16π-electron circuit of the porphyrin is the main contributor together with a minor paratropic ring current on the outer 20π-electron circuit. Conformational analyses of bis(biphenyl carboxylate) complexes of SnIV(tetraphenylporphyrin) in solution were carried out with this porphyrin ring current effect model.
■ Synthesis of 5-(Adamantan-1-yl)-4,4-dimethyl-1-(3-oxyphenyl)-2,6,7-trioxabicyclo-[3.2.0]heptanes and Their Base-Induced Chemiluminescent Decomposition in Liquid/Solid Phase
Masakatsu Matsumoto,* Masatoshi Tanimura, Masahiko Tachi, and Nobuko Watanabe
*Department of Chemistry, Kanagawa University, Tsuchiya, Hiratsuka, Kanagawa 259-1293, Japan
Singlet oxygenation of 4-(adamantan-1-yl)-5-(3-hydroxy)phenyl-1,2-dihydrofuran 4a effectively gave bicyclic dioxetane 3a as crystals with a high melting point. Dioxetane 3a decomposed rapidly accompanied by the emission of blue light, when treated with tetrabutylammonium fluoride (TBAF) in DMSO or acetonitrile. The chemiluminescence efficiency for 3a was as high as those for tert-butyl-analog 2. In addition to chemiluminescent decomposition in a liquid phase, a finely powdered mixture of crystalline 3a and crystalline dimethylaminopyridine (DMAP) emitted blue light upon heating at 80-110 °C while maintaining a solid state.
■ Synthesis of 6-Pyridylaminopurines
Luc Demange, Nassima Oumata, Julia Quinton, Serge Bouaziz, Olivier Lozach, Laurent Meijer, and Hervé Galons*
*INSERM U648, Université Paris Descartes, 4, avenue de l'Observatoire 75006 Paris, France
An efficient synthesis of new 6-pyridinylaminopurines was developed based on Buchwald-Hartwig coupling reaction between aminopyridines and 2,6-dichloro-9-iso-propylpurine. The reaction was best carried out in the presence of a limited load of palladium acetate (4 %) as catalyst, racemic 2,2'-bis(diphenylphosphanyl)-1,1'-binaphtyl (8 %) as ligand and potassium tert-butoxide as base. Rising the load of catalyst, or using other catalysts and bases led to the development of side reactions.
■ Facile Synthesis of 2-Anilinopyrimido[4,5-e]-[1,3,4]thiadiazines
Mehdi Bakavoli,* Mohammad Rahimizadeh, Ali Shiri, Hossein Eshghi, and Mohsen Nickpour
*Department of Chemistry, School of Sciences, Ferdowsi University, Mashhad 91775-1436, Iran
One-pot synthesis of 2-anilino-pyrimido[4,5-e][1,3,4]thiadiazines through intermediates formed by reaction of 5-bromo-2-chloro-6-methyl-4- (1-methylhydrazino) pyrimidine with arylisothiocyanates is reported.
■ Synthesis of Novel N-Substituted 6-Chlorothieno[2,3-e]-1,4,2-dithiazin-3-amine 1,1-Dioxides
Rajab Abu-El-Halawa,* Mahmoud H. Al-Refai, Mustafa M. El-Abadelah, and Hani D. Tabba
*Chemistry Department, Faculty of Science, Al al-Bayt University, Mafraq, Jordan
A series of N-(substituted)-6-chlorothieno[2,3-e]-1,4,2-dithiazin-3- amine 1,1-dioxides (9a-g) were prepared via direct interaction of the appropriate isothiocyanate with 2,5-dichloro-3-thiophenesulphonamide 6 in THF in the presence of sodium hydride. The structures of these new bicyclic derivatives are based on microanalytical and spectral (IR, MS, and NMR) data.
■ Thiophene Derivatives from the Aerial Part of Pluchea indica
Yun-Qi Qiu, Shu-Hua Qi, Si Zhang,* Xin-Peng Tian, Zhi-Hui Xiao, MIn-Yi Li, and Qing-Xin Li
*1Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, P. R. China
Chemical investigation on the aerial part of Pluchea indica resulted in the isolation of two new thiophene derivatives, 2-(4-hydroxy-3- methoxybut- 1-yn-1-yl)-5-(penta-1,3-diyn-1-yl)thiophene (1) and 2-(4-O-β-glucopyranosyl- 3-hydroxybut-1-yn-1-yl)-5-(penta-1,3-diyn-1-yl)thiophene (2) along with three known thiophene derivatives 2-(3,4-dihydroxybut-1-yn-1-yl)-5-(penta-1,3-diyn-1-yl)thiophene (3), 2-(3-acetoxy-4-hydroxybut-1-yn-1-yl)-5-(penta-1,3-diyn-1-yl) thiophene (4) and 2-(prop-1-yn-1-yl)-5-(6-acetoxy-5-hydroxyhexa-1,3-diyn-1-yl) thiophene (5). The structures of 1 and 2 were determined on the bases of extensive spectroscopic analysis, including 1D and 2D NMR data. Antimicrobial activities of compounds 1-5 were tested.
■ A Facile Synthesis of Imidazo[1,5-b]pyridazines from 3-Formylchromones
Andrey S. Plaskon, Sergey V. Ryabukhin,* Dmitriy M. Volochnyuk, Alexander N. Shivanyuk, and Andrey A. Tolmachev
*Enamine Ltd. 23 A. Matrosova st., 01103 Kyiv, Ukraine
The recyclization of 3-formylchromones promoted by chlorotrimethylsilane with 1-amino-1H-imidazoles results in a set of imidazo[1,5-b]pyridazines is obtained in high preparative yields. It's found that the reaction is sensitive to the structure of NNC-binucleophiles.
■ A Facile Synthesis of Novel Heteropolycyclic Pyrazines and Oxazoles Mechanistic Studies of 2,3-Dihydrobenzo[de]chromene-7,8-dione with Amines
Hua-pei Jian, Xing-yuan Wang, Zhi-shu Huang, Shi-liang Huang,* and Lian-quan Gu
*School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510080, P. R. China
A series of novel heteropolycyclic pyrazines and oxazoles were synthesized by the reaction of 2,3-dihydrobenzo[de]chromene-7,8-dione (compound 1) with amines in mild reaction conditions. The mechanisms for these reactions were discussed.
■ Synthesis of 1H-Isoindoles by Iodoamination of 2-Vinylbenzylidenamines
Kazuhiro Kobayashi,* Mai Horiuchi, Miyuki Tanmatsu, and Hisatoshi Konishi
An efficient method for the synthesis of 1H-isoindole derivatives is described. It is based on iodine mediated cyclization of aryl(or alkyl)(2-vinylbenzyliden)amine derivatives, which can be easily prepared from the reactions of 2-lithiostyrene derivatives with various nitriles, furnishing the corresponding iodoamination products, 3-aryl(or alkyl)-1-iodomethyl-1H-isoindole derivatives, in satisfactory overall yields.


Xoriant has been involved in developing multidimensional, interactive D3.js visualizations for a number of its clients. The knowledge and experience gained by our engagement team and technical personnel has led to the development of Xoriant Visualization (XViz) framework.
Xoriant's proprietary XViz Framework is developed to create and deploy complex data visualizations on any device (handheld or otherwise) supporting a web browser or a web view.
The XViz framework comprises of multiple independent modules used for preloading of files and data required for visualizations, data parsing, view rendering and communication between visualizations as well as communication between visualizations and native device code. Visualizations developed using the XViz framework are independent in that they can be deployed by themselves wherever they are required and do not depend upon the existence/inclusion of other visualizations.


Last night I turned my light off around midnight as usual, but my mind would not turn off until hours later. I have so many great ideas for this site, some of which are perhaps a little overly ambitious, but still fun ideas that I look forward to trying and sharing with you.
This morning I have been organizing my existing catalogue of plants based on the colour of the petals. And I am trying to figure out the best way to sort within the colour categories - number of petals? season? ...to be determined. I also couldn't resist a morning stroll to go with my coffee on this gorgeous day, which ended up expanding my catalogue with tall rattlesnake root, a new flora find.
I always get excited each time I find a new wildflower, well, one that is new to me at least.
Notes from wanderings, reflections, news and stories.


Martin's fitness services are built on one clear goal: to help people transform their body. His website needed to deliver that message clearly.
Martin had already delivered plenty of amazing body transformation results, so we organized his web design around those and the elegant brand his logo represented.
The website is clean, clear, has plenty of white space and targets people who are looking for support in their venture to become their best possible self.
Get in touch to talk about your website design project.


Cryptocurrency communities are finding more reasons to worry about Tether, the leading stablecoin by market capitalization. A post on Reddit notified the community that Tether (USDT) had updated how it holds its collateral.
The original white paper required Tether tokens to be backed by dollars in the bank. These reserves have not been audited, and only twice has the company provided putative third-party verification of its balances.
But some observers thought differently. Some saw it as a "discreet" bid to face off scrutiny from the CFTC. Others speculated that the company was seeking to loan out its vast reserves and profit from the interest; some even alleged that it was a sure sign of an exit scam.
Crypto Briefing reached out to people from around the sector to find out what the changes meant.
Most agreed that Tether was looking to make a profit from its collateral. George Harrap, the co-founder and CEO of Bitspark, said it was a sign Tether was turning "into a bank." The change does not benefit USDT holders, Harrap said, if the stablecoin is prioritising profit over the security of its holdings.
"[I]t gives [Tether] the ability to run a fractional reserve and make more money," he said.
If stablecoins remain fully collateralized, Harrap believes holders can be confident in their underlying value because they can be redeemed. There's no problem if investors can seamlessly swap their tokens for fiat currency, and vice a versa.
But when there isn't collateral, a stablecoin project runs the risk of a "run on the bank situation." People who can't redeem value could start to "panic sell," flooding the market with tokens and driving the price down.
Stablecoins have 'slipped' in the past. In one week in October, Tether's market cap plummeted, and so did the price. USDT's market-wide price fell by $0.04 in the space of one morning, and could be bought for as low as $0.72 on Kraken.
Tether's price fluctuations in October, 2018. Source: CryptoCompare.
As investors divested out of Tether, the price of TrueUSD (TUSD) increased to 1.07.
Stablecoins provide safe stores of value for the market. Armin Schmid, CEO of Swiss Crypto Tokens AG, believes stablecoins which are regulated and transparent about their underlying assets provide credibility and long-term sustainability to the sector.
Tether's decision to loan out some of its collateral is a fundamental risk. For wary investors, it's somewhat reminiscent of what happened to QuadrigaCX, the Canadian exchange whose owner mysteriously died on honeymoon in India. The platform's native CAD tokens, a form of stablecoin, dropped in value because there was not enough collateral for holders to redeem their value.


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Failed Tory candidate forced to deny comparing Corbyn to Hitler in vile tweet about Grenfell Tower
A failed Tory parliamentary candidate has been forced to deny comparing Jeremy Corbyn to Adolf Hitler in a tweet allegedly attacking Corbyn for visiting victims of the Grenfell Tower fire.
Michelle Lowe, who is deputy leader of Sevenoaks Council in Kent, lost her bid to become MP for Coventry South to Labour's Jim Cunningham earlier this month. Earlier this week, the Coventry Telegraph revealed that she posted a photo of Adolf Hitler meeting the public on Twitter alongside the caption "Politicians should go out and hug the public more. It proves they are nice people." When questioned about who the tweet was about, she merely responded "I will leave you to interpret as you wish."
The timing of the tweet is particularly suspect, as Jeremy Corbyn had been making efforts to meet those involved in the horrific Grenfell Tower fire over the weekend.
Michelle Lowe is now under fire from all corners. Her local council, Conservative Party, Labour Party and MPs in parliament have condemned her crass remarks. While Lowe strenuously denies that she was trying to make a comparison between Corbyn and Hitler, social media users pointed out the clear and evident implication in her tweet.
The leader of the Conservative Party in Coventry, Gary Ridley, said:
"As Leader of the Conservative Party, in a city which still bears the scars of Nazi aggression, I'm disturbed by any attempt to use Adolf Hitler to make a political point.
He brought pain and suffering to the world on an unimaginable scale and was responsible for the deaths of millions of innocent people.
To evoke his memory in this way is disrespectful to those who suffered at the hands of this monster and trivialises the crimes of the Nazi regime."
Meanwhile, the victor of the race to become MP for Coventry South, Jim Cunningham, said:
"Comments and remarks like this are so far away from what most people are concentrating on in the wake of awful tragedies.
It beggars belief that a senior Tory, someone who recently thought they should be an MP for Coventry, thinks this is acceptable.
The Tories must stand up and take a stance against these offensive comments, they have no place in political discourse."
In her response to the accusations, Ms Lowe claimed that the photo was actually in defence of Theresa May being so reserved in meeting victims and the public following the Grenfell Tower fire. She told the Coventry Telegraph:
"The purpose of the tweet was not to cause offence but to point out that just because some people are reserved and not as able to be as familiar with strangers as others it does not mean they don't care about their suffering.
It was a comparison with Theresa May and no one else dealing with the Grenfell Tower victims – for which she took a lot of criticism – and nothing else."
Despite her passionate defence of the tasteless tweet in this statement, the photo was deleted shortly afterwards.
In the words of Michelle Lowe herself, we will leave you to interpret it how you wish.


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Q: Responsively scale an absolutely positioned element I have a circle which needs to have an absolute position as per the attached design. I can achieve the positioning but it doesn't scale responsively with the viewport width. Kindly suggest how can I have a responsive image along with the absolute position. Below is the CSS I applied to the image.
.upper-partial-circle
{
    position:absolute;
    z-index: 1;
    left: -10%;
    max-height: 300px;
    top: -1%;
}

A: I would try give it a width or height with viewport units. For example height: 10vw; so it's height will be always 10% of the screen's width.
codepen.io/RoniFlash/pen/wvBxbwM
HTML:

CSS:
body {
  position: relative;
  width: 100vw;
  height: 100vh;
  margin: 0;
}

div {
  width: 10vw;
  height: 10vw;
  background-color: #fff;
  position: absolute;
  top: -5%;
  left: -5%;
  border-radius: 50%;
  border: 2px solid #000;
}

redpajama_set_name: RedPajamaStackExchange


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Tour LeBron James' $36.75M Beverly Hills House
Top 5 Things To Do in the Winter Wonderland of Charlevoix That You'll Never Forget
The Lakers star LeBron James has purchased a stunning Beverly Hills mansion for $36.75 million. Take a look inside LeBron's new Beverly Hills house, which is today's daily dream home!
Located on 2.5 acres, the NBA star's new house was purchased from the estate of Lee Phillip Bell (the "The Young and the Restless" co-creator passed away earlier this year). LeBron's new house at 9955 Beverly Grove Dr., features seven fireplaces, a pool house with two baths, lighted tennis court, and screening room.
The huge Beverly Hills mansion has the proportions to accommodate all 6 feet and 9 inches of the LA Lakers star, with more than 9,100 interior square feet and vaulted, exposed-beam ceilings.
Featuring a hedge-lined driveway and palm-topped motor court, the primary estate spans 9,100 square feet with four bedrooms and eight total bathrooms. It was built in the 1930s but updated over the years during Bell's ownership.
Pandemic Pivots: A Luxury Desk Designed with HER in Mind
Bell's former estate has been kept in wonderful shape, which was listed with Hilton & Hyland founders Jeff Hyland and Rick Hilton in June. And before being purchased by the Bell family, the estate was owned by legendary actress Katherine Hepburn.
The four-time NBA MVP paid $36.75 million, slightly below the original listing price of $39 million, for the Mediterranean-style Beverly Hills house.
Beverly HillsDaily Dream HomeLeBron JamesThe Lakers
Joan Stern November 10, 2020
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Inside The 5-Star Beverly Wilshire Hotel As It Safely Reopens
Cocktails At Home: The Feeling Pretty From Beverly Wilshire
Daily Dream Home: A Hamptons-Inspired Escape in Naples, Florida
Tour The Weeknd's $24.995M California Mansion


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Eine Deckungsstelle (Abkürzung: Dkst) ist bei den deutschen Eisenbahnen eine Betriebsstelle der freien Strecke, die den Bahnbetrieb an beweglichen Brücken, höhengleichen Kreuzungen von Bahnen, Gleisverschlingungen und Baustellen sichert. Einer Deckungsstelle können gleichzeitig die Funktionen einer anderen Betriebsstelle übertragen sein, z. B. die einer Blockstelle, Abzweigstelle oder Anschlussstelle.

Die genannten Gefahrenstellen sind in der Regel mit Hauptsignalen abgesichert. Hauptsignale einer Deckungsstelle, die nicht zugleich Blockstelle oder Abzweigstelle ist, sind nicht in den Streckenblock eingebunden; sie heißen dann Deckungssignale. In der Praxis gab bzw. gibt es auch Deckungssignale vor kombinierten Schiene/Straße-Brücken und gefährlichen Bahnübergängen.

Bewegliche Eisenbahnbrücken auf der freien Strecke werden fast ausnahmslos durch Deckungsstellen gesichert.

Bei Deckungsstellen mit älterer Signaltechnik ist beiderseits der Brücke ein Formhauptsignal aufgestellt, bei einfachen Verhältnissen kann es auch ein Signal Sh 2 sein (alte Bezeichnung: Deckungscheibe Ve 1). Beispiele: Klappbrücke Lindaunis mit Formhauptsignalen, Drehbrücke Sanderbusch mit Deckungscheiben; mittlerweile beide durch Ks-Signale als Block- und Deckungssignale ersetzt. Das Deckungssignal einer auf dem der Bedienungsstelle gegenüberliegenden Ufer einer beweglichen Brücke kann allerdings nur elektrisch betätigt werden.

Bei beweglichen Brücken auf zweigleisigen Strecken befand sich am Regelgleis ein Formhauptsignal und am linken (früher: falschen) Gleis eine Deckungscheibe.
Beispiel: Klappbrücke Itzehoe bis 1983, Drehbrücke Friedrichstadt bis 1988.

Bei der Deutschen Reichsbahn wurden in den 1960er Jahren Deckungscheiben vor beweglichen Brücken fast überall abgebaut und in der Regel durch Lichthauptsignale ersetzt, es verblieben lediglich zwei Signalpaare bis in die Nach-Wende-Zeit.

Bei Deckungsstellen mit neuerer Signaltechnik ist beiderseits der Brücke ein Lichthauptsignal aufgestellt; es kann durch ein Lichtsperrsignal ergänzt sein.
Beispiel: Klappbrücke Weener (Friesenbrücke).

Die meisten beweglichen Eisenbahnbrücken befinden sich innerhalb von Bahnhöfen / Hafenanlagen. Sie werden durch Lichthauptsignale (Kattwykbrücke Hamburg oder Ziegelgrabenbrücke Stralsund), Lichtsperrsignale (Mannheim, Oldenburg, Emden, Lübeck u. a.), Gleissperren (Harburg), Deckungscheiben (Elisabethfehn), im Gebiet der Deutschen Reichsbahn bei Erfordernis für Rangierfahrten zusätzlich durch Rangierhaltsignale (Wartezeichen Ra 11b, Anklam). Bei Lichtsignalen kommen vereinzelt Sonderbauarten zur Anwendung.

Quelle
 Serie "Besondere Brücken" in der DREHSCHEIBE
 Deckungsstelle bei tf-ausbildung.de
Bahnanlagentyp


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PG is currently an ingredient used in all vaping products, but it is a chemical derivative from the transformation of petroleum. In fact, unfortunately it can cause various unpleasant effects. PG is highly hygroscopic, causes dry mouth, is sometimes excessively annoying in the throat or causes gastrointestinal discomfort, may be poorly tolerated by some subjects.
In some cases it can cause real allergies. Through various studies it has been hypothesized that one third of users are intolerant to it in various forms. Unfortunately, more and more frequently, there are people who just can't vape consistently due to annoying effects mostly related to propylene glycol and are forced to abandon the electronic cigarette.
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Reference MCPRO1558
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text:
The Best of Both Styles: Schlafly Releases India Pale Lager
The Best of Both Styles: Schlafly Releases India Pale Lager [/vc_column_text] Schlafly Beer, the largest locally owned brewery in St. Louis, announces the release of India Pale Lager, a beer that blends the assertive hoppiness of an IPA with the crisp refreshment of a lager. IPL is the next offering in Schlafly's Hop Allocation Series, the brewery's series of hop-forward...
Use your Illusion: Six of the Best Cocktail-Inspired Beers Ranked
Schlafly Beer Ranks #1 of Best Cocktail-inspired Beers There are beers, there are cocktails, and there are beer cocktails. Then, there are also beers that taste like cocktails. Cocktail-inspired beers are a new style of beverage that inventive brewers have brought to our attention in recent years. The experimental spirits (no pun intended) of brewers like Pipeworks Brewing, Brooklyn Brewery, and Two Roads Brewing...
Brewer Magazine: How Failure Can Help Shape Your Future
"There can be no growth without failure," noted Karben4 co-founder Zak Koga. "Every slight miscalculation with a beer style, recipe, branding, timing, etcetera, is part of our story in creating what we hope will ultimately be success. The key is to really embrace the process and not the outcomes — at least that's what I'm trying to tell myself."All failure is invaluable....
Bigger is Better for Summer: Schlafly Introduces 12-Packs of Hoppy Wheat Cans
Schlafly Beer announces today the roll-out of 12-packs of Hoppy Wheat in 16-ounce cans. The can release of the popular, warmer-weather seasonal furthers the Saint Louis Brewery's™ footprint in larger format cans. Schlafly Beer was the first brewery in St. Louis brewery to offer 12-packs of 16-ounce cans with White Lager in December 2017. Hoppy Wheat also continues Schlafly's value...
Schlafly Beer Partners with National Forest Foundation
(ST. LOUIS; April 6, 2018)—Schlafly Beer announces today a partnership with the National Forest Foundation, the nonprofit partner of the U.S. Forest Service that works to promote the health and public enjoyment of America's 193-million-acre National Forest System. The largest, locally owned craft brewery in St. Louis chose to support the organization as part of their overall 2018 sustainability mission. Other initiatives...
For the Record: Schlafly's Pilsner Box gets a Facelift
We love a craft beer promotion that supports another craft or small business because it reinforces that spirit of community and independence that's crucial for the industry (and we dare say, society).
The Love of Pale Ale
It saddens me a bit that back in 1992 when I tried my first craft beer — a Schlafly Beer Pale Ale; I did not have the foresight to realize I was tipping back something special. I didn't know that it would not only mean something to me 27 years later but inspire me to write about it.
Hop Allocation: Northeast IPA makes its way to the Midwest
If you don't know about Northeast IPAs (some call them New England IPAs or just NE IPAs) then you haven't been paying attention. In the last few years, these beers have migrated from the East Coast to all over the country.
Kick Off: Schlafly Beer announces release of Raspberry Chipotle Brown Ale
The series, which began last year, gets a new look for 2018. The bottle design now showcases the research and development inside each of the inventive beers with a handwritten look and feel and a descriptive neck tag.


text:
Trailer for Tom Bradby's interview with Prince Harry released
January 5, 2023, 7:55 a.m.
In a promotional clip ahead of Sunday's interview, Tom Bradby puts difficult questions to Prince Harry about privacy.
TOM BRADBY: Some people will say You have railed against invasions of your privacy all your life. But the accusation would be, here are you invading the privacy of your most nearest and dearest without permission. That will be the accusation.
PRINCE HARRY: That would be the accusation from the people that don't understand, or don't want to believe that my family have been briefing the press.
TOM BRADBY: If you're invited to the Coronation, will you come?
PRINCE HARRY: There's a lot that can happen between now and then. But the door is always open. The ball is in their court. There's a lot to be discussed, and I really hope that they are willing to sit down and talk about it.
TOM BRADBY: Do you still believe in the monarchy?
PRINCE HARRY: Yes.
TOM BRADBY: Do you believe you will play a part in its future?
PRINCE HARRY: I don't know.
The best in season fruits, vegetables to buy in Canada during the winter
Nue Just Released the Ultimate Reusable Nipple Covers
Following the super successful launch of its much-loved breast tape, Nue just dropped an all-new...
PureWow
Kate Middleton Just Proved This Royal Rule No Longer Applies (at Least to Her)
Kate Middleton just confirmed what we all saw coming: The royal family's "no selfie" rule is no longer enforced. This week, Princess Catherine traveled to Leeds to promote her new campaign, Shaping Us, which supports early childhood development. While there, the royal visited the Leeds Kirkgate Market and chatted with vendors about her initiative. The Princess of Wales also proved that the royal family's "no selfie" rule doesn't apply anymore. (Well, at least to her.) The Princess of Wales very
Teacher floors Simon Cowell on 'AGT: All-Stars': 'Best performance I've seen all series'
The search for the No. 1 act continued on NBC's "AGT: All-Stars" Monday in the fifth week of auditions. Singer Tom Ball earned the Golden Buzzer.
Kate Middleton Stepped Out in a Bodycon Dress and Emerald Coat for a Visit to Leeds
Fresh off wearing a red wrap blazer with a plunging neckline yesterday in London, Kate Middleton tried a cream bodycon dress while visiting the University of Leeds.


Chris Paul's eighth signature shoe is a high-performance basketball shoe built for one of the top point guards to ever play.
.Flight Web fit system and textile for lightweight ventilation and lockdown.
.Dual-density cushioning in the heel and Nike Zoom unit in the forefoot for low-profile, responsive cushioning.
.TPU chassis for lateral stability.
.Rubber pods placed in high contact areas for lightweight durability.
.Heel and toe herringbone pattern for multidirectional traction.


As always, Banque Misr with its appreciation of the importance of science, and belief that today's youth are the generations of the future; Mr.Mohamed Kamal El Din Barakat, Chairman of Banque Misr and Banque Du Caire, honored a group of Thanaweya Amma's Top students for the year 2006/2007. furthermore Mr. Mohamed Ozalp, Deputy chairman ,honored the top Thanaweya Amma students of 2007/2008.They were granted a Banque Misr saving account dotted with EGP 10.000 in the first year as well as a distinguished Certificate worth another EGP 10.000 in the second year, in addition to a BM Card . Mr. Mohamed Barakat said that these top students deserve appreciation for succeeding to achieve top positions despite their difficult circumstances; especially that each of them had a success and struggle story worthy of respect. This award comes to reflect a part of the bank's commitmenttowards the Egyptian society through presenting the BM youth card which adds a new social dimension as these cards have the effect of refreshing commercial activity in addition to being a way for simplifying financial transactions. The BM youth card gives students a feeling of independence and responsibility, and is also a modern, safe method for buying. The holder of the card can also use it to withdraw cash from ATM machines spread nationwide ..


Read Psalm 34 all the way through at least once. Then go back through the entire Psalm and take the extra step to write out the descriptions of God that you see. If you're really bold, mark in your Bible! Underline or circle the descriptions of God. If one of the characteristics you are magnifying pricks your spirit and uncovers a lie, write that verse out on a sticky note and replace the lie with the truth daily. Oh, magnify the Lord with me, and let us exalt his name together.


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This round: RPGs. The Japanese RPG market exploded in the 32-sixty four little bit days, blowing out with a new sport seemingly each 7 days. You can blame Square for that 1, bringing to the stores incredible sport following incredible sport, which instantly spurned each other business to launch whatever dreck they could muster to maintain you pumping money into their pockets. Nowadays there are hundreds of choices Brawl Stars Free Gems out there, and the Japanese market isn't the only 1 around. North American companies have their own solutions to the RPG increase and now it's a veritable flood of options. Here are the top five for every option you've received.
Mystery, Alaska (1999)- This is my preferred ice hockey film. Russell Crowe stars as John Biebe, sheriff of the city and member of the Thriller, Alaska hockey team. After an article in Sports activities Illustrated is written about the players of Thriller, a sport is set up between them and the New York Rangers. Although they shed the game five-4, they are celebrated by the town anyway and even make the regard of the Rangers. Burt Reynolds and Hank Azaria co-star.
38.Turned down the Val Kilmer role in Heat to do a manufacturing of Hamlet in Canada. If I haven't said it before, allow me say it now, the guy is devoted to his craft. He works on it, he tries new issues. He keeps working. Even if you believe he's not obtaining better, at least he's trying. How many film stars maintain pushing themselves following they strike it big? How numerous just coastline along on generic roles and unspectacular performances? Keanu pushes himself. Screw all to his limitations, he pushes himself and I regard him for it.
There are a ton of fantastic video games for the Wii. The ones that are great have been played by thousands of players who have verified that they're the very best. So, what I'm heading to do is share with you the very best games for Wii that are downloadable.
Continuing the brawl. Now it is the darkus brawler's turn, because he gained't say the exact same factor you did last time. "Gate card set, bakugan brawl darkus laser guy stand". Now it's the Haos brawler's flip. "Bakugan Brawl Stars Gems generator haos tuskor stand". Haos Tuskor stood on Darkus laserman's card so there is yet another battle.
The graphics are better of program, but not by much. Sometimes the sport will even remind you of Melee especially if you play in a Melee level. The stages and the figures are more comprehensive and you'll see cool effects that's not feasible in Gamecube during a final smash. Super Smash Bros. Brawl will certainly remind you of Melee, but there are enough modifications and enhancements in graphics and gameplay that you'll know you're taking part in Brawl.
Choose your three bakugan. This is most likely 1 of the most important actions because you need to determine what bakugan you will be using the entire game. You might want to use bakugan if you have their character card or if their printed g-power is really high. Also, you might want to use bakugan who have the right g-power to function with your command playing cards.
Super Smash Bros. Brawl has been out for a couple of times and after having performed it a lot of occasions, I'd have to say this is the very best Super Smash Bros. however. Nevertheless, that doesn't imply everything feels enhanced more than prior versions but nearly everything is. I'm referring to the characters particularly. I'm sure I'm not the only 1 who feels this way about the figures they like to use. There is always some type of change to your preferred character heading from one installment to the next. It might be much better and it might be worse.
That is why the choice of key phrases is so important if you want post popularity. Today, if you wrote an article on Anna Nicole Smith and placed her title in the title of the article, in the content material of the post, and the keyword entry, you would get a Brawl Stars Gems generator great deal of readers.
My 6 yr previous grandson is fascinated by them and did not have any of his own till now. His mom and I experienced quite the squabble about them. Because he stored "borrowing" them from the teacher's desk, and defended himself from a bigger child at school who attempted to take 1 absent from him, my daughter thinks they are evil because he is so enthralled with them. I believe that was because he did not have any of his personal which could have prevented a great deal of problems if he did personal some of his personal. Perhaps if she purchased some for my 5 year previous Brawl Stars Free Gems grandson, he would be less inclined to "borrow" from others.
Metroid Prime three: Corruption: Metroid Prime 3 is probably the best initial individual shooter on the Nintendo Wii. In addition to becoming a first person shooter, it is also an journey game that allows you explore vast worlds. It might be sensible to perform the other Metroid Primary games Brawl Stars Gems generator prior to embarking on this 1.
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st_aightfo_wa_d_guidance_on_fundamental_details_fo_b_awl_sta_s_f_ee.txt · Last modified: 2021/11/12 10:46 by maurinewiseman1