text:
Q: I added linear gradient to text and applied animation to each alphabet. But the text gradient showing only after completing animation. Why? I added animation to a text with a linear gradient. But the gradient effect on text shows only after completing the animation. Text animation working properly. The issue is only with the text gradient. How to do the animation to text with gradient?

ul {
    list-style: none;
    display: flex;
    cursor: default;
    justify-content: center;
    transition: 5s;
    align-items: center;
    position: relative;
    z-index: 1;
    top: 35vh;
    left: -4%;
}

li {
    font-size: 12vw;
    font-weight: bolder;
    margin: .1em;
    position: relative;
    background: -webkit-linear-gradient(green, yellow);
    background: linear-gradient(green, yellow);
    background-clip: text;
    color: transparent;
    -webkit-background-clip: text;
    -webkit-text-fill-color: transparent;
    -webkit-text-stroke: 1px rgb(76, 70, 245);
}

li::before {
    content: attr(data-text);
    position: absolute;
    top: 0;
    left: 0;
    z-index: -1;
    text-shadow: .02rem -.02rem .1rem gray,
        .05rem -.05rem .1rem gray,
        .08rem -.08rem .1rem gray,
        .11rem -.11rem .1rem gray,
        .14rem -.14rem .1rem gray,
        .17rem -.17rem .1rem gray,
        .20rem -.20rem .1rem gray,
        .23rem -.23rem .1rem gray,
        .26rem -.26rem .1rem gray,
        .29rem -.29rem .1rem gray,
        .32rem -.32rem .1rem gray,
        .3rem .2rem .5rem gray;

}

@keyframes year {
    50% {
        transform: translateX(-5vw) translateY(-35vw) rotate(-180deg);
    }

    100% {
        transform: rotate(-360deg);
    }
}

li:nth-child(1) {
    animation: year 2s linear;
}

li:nth-child(2) {
    animation: year 2s linear;
    animation-delay: 1s;
}

li:nth-child(3) {
    animation: year 2s linear;
    animation-delay: 2s;
}

li:nth-child(4) {
    animation: year 2s linear;
    animation-delay: 3s;
}

2

0

2

2

Please help me do the animation with the text gradient shown from the beginning of the animation.

A: The use of transform create a stacking context which disable the z-index: -1 you are using.
Do it differently by using the other pseudo element to create the gradient coloration

ul {
    list-style: none;
    display: flex;
    cursor: default;
    justify-content: center;
    transition: 5s;
    align-items: center;
    position: relative;
    z-index: 1;
    top: 35vh;
    left: -4%;
}

li {
    font-size: 12vw;
    font-weight: bolder;
    margin: .1em;
    position: relative;
    color: transparent;
}

li::before {
    content: attr(data-text);
    position: absolute;
    top: 0;
    left: 0;
    text-shadow: .02rem -.02rem .1rem gray,
        .05rem -.05rem .1rem gray,
        .08rem -.08rem .1rem gray,
        .11rem -.11rem .1rem gray,
        .14rem -.14rem .1rem gray,
        .17rem -.17rem .1rem gray,
        .20rem -.20rem .1rem gray,
        .23rem -.23rem .1rem gray,
        .26rem -.26rem .1rem gray,
        .29rem -.29rem .1rem gray,
        .32rem -.32rem .1rem gray,
        .3rem .2rem .5rem gray;
}
li::after {
    content: attr(data-text);
    position: absolute;
    top: 0;
    left: 0;
    background: linear-gradient(green, yellow);
    background-clip: text;
    -webkit-background-clip: text;
    -webkit-text-fill-color: transparent;
    -webkit-text-stroke: 1px rgb(76, 70, 245);
}

@keyframes year {
    50% {
        transform: translateX(-5vw) translateY(-35vw) rotate(-180deg);
    }

    100% {
        transform: rotate(-360deg);
    }
}

li:nth-child(1) {
    animation: year 2s linear;
}

li:nth-child(2) {
    animation: year 2s linear;
    animation-delay: 1s;
}

li:nth-child(3) {
    animation: year 2s linear;
    animation-delay: 2s;
}

li:nth-child(4) {
    animation: year 2s linear;
    animation-delay: 3s;
}

2

0

2

2


text:
Aaron Finch Gives a Hint of Josh Hazlewood's Inclusion for Rajkot
Australia captain Aaron Finch has given a hint of right-arm pacer Josh Hazlewood might get a chance in the second ODI to manage the workload of Pat Cummins and Mitchell Starc. Australia thrashed India by 10 wickets in the first ODI in Mumbai where Starc and Cummins picked up five wickets between them with their superb […]
By Shruti - Jan 17, 2020
Aaron Finch Reveals the Reason Behind Team India's Loss
Australia captain Aaron Finch said that their fightback helped them to get back in the game in the middle overs during their first ODI against India at the Wankhede Stadium in Mumbai. Finch and his opening partner David Warner ensured that Australia chased down a target of 256 with ease. Even they won the game […]
"We Complement Each Other Very Well": David Warner on the Partnership with Aaron Finch
Flamboyant Australia opener David Warner and Aaron Finch dismantled the Indian bowling attack by stitching an unbeaten 258-run stand in their chase of the 256-run target. However, Warner said both of them complement each other well on the field. "We complement each other on the field and we're great mates off the field as well. […]
Shikhar Dhawan Praises David Warner After Mumbai ODI
On Tuesday, the Indian opener, Shikhar Dhawan went on to say that the loss of four quick wickets on both the sides of the 30th over was one of the crucial reasons behind India's crushing 10-wicket loss to Australia in the first ODI in Mumbai. Dhawan went on to score 74 before India being bundled-out […]
By CricShots - Jan 15, 2020
Twitterati Erupts As India Suffered A Dominating Loss In Mumbai
Australia have outplayed India in all the three departments without even breaking much of a sweat in the first of the three-match ODI series to take a 1-0 lead at the Wankhede Stadium in Mumbai. Their bowlers were simply fantastic before the Aussie openers, David Warner and skipper Aaron Finch scoring centuries during the chase. […]
"I think he has just matured as a cricketer": Andrew McDonald on Aaron Finch
Australia captain Aaron Finch has matured a lot as a cricketer and filled the void place in terms of captaincy in the limited-overs cricket feels Australia's stop-gap coach Andrew McDonald. Australia will play a three-match ODI series against India starting January 14. "I think the growth of Aaron Finch in his leadership role in the […]
Australia Want to Win the Series Against India, Says Aaron Finch
Australia captain Aaron Finch hopes a good performance by his team in India would help bring smiles back to the faces of people who are currently suffering in bushfires at home. The devastating fire has killed at least 26 people and their tour has overshadowed their tour. "Obviously it's very unfortunate what's happening in Australia and […]
"A big part of playing in India is how you play spin": Marnus Labuschagne
In-form Australia batsman Marnus Labuschagne said that he considers the upcoming ODI series against India will be a big opportunity. He scored back-to-back Test centuries against Pakistan and became the vital cog for Australia. Australia will play a three-match ODI series against India starting January 14 in Mumbai. "You look at the guys I look […]
Important to Not Overplay Jasprit Bumrah Threat, Says Aaron Finch
Australia captain Aaron Finch on Friday said that it is important for his side to not "overplay" the Jasprit Bumrah factor in the upcoming three-match ODI series against India. India's pace spearhead Bumrah has returned to action after a three-month injury lay-off, and the visiting side – Australia team are aware of the threat he […]
Aaron Finch Sure About His Game-plan For The ODI Series Against India
The Australian team has the mettle in them to beat Virat Kohli and his men, feels skipper Aaron Finch. The men in yellow left for India for the three-match series on Thursday. The two sides face each other in Mumbai on January 14 before heading to Rajkot and then Bangalore for what will be Australia's […]
By CricShots - Jan 9, 2020
KL Rahul Feels Proud To Be Compared With Rahul Dravid
Virat Kohli Showered Praises For Rahul And Dhawan
IND vs AUS (2nd ODI): India Made A Strong Comeback In Rajkot
WATCH – KL Rahul Affected Brilliant Stumping To Dismiss Aaron Finch
WATCH – Manish Pandey Pulled-off A One-handed Jumping Catch
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redpajama_set_name: RedPajamaCommonCrawl


text:
Jeremy John Elton Lefroy (né le ) est un homme politique britannique du Parti conservateur. Il est député de la circonscription de Stafford de 2010 à  2019.

Jeunesse et carrière
Lefroy est né le  à Londres, en Angleterre . Il fait ses études à Highgate School, une école indépendante à Highgate dans le nord de Londres . Il étudie au King's College de Cambridge, où il obtient un baccalauréat ès arts (BA) en 1980 : selon la tradition, son BA a été promu à une maîtrise ès arts (MA Cantab) en 1984.

Lefroy vit et travaille dans l'industrie du café en Tanzanie entre 1989 et 2000. Il est expert-comptable diplômé .

Il fonde également et dirige Equity for Africa, une fondation caritative qui cherche à réduire la pauvreté de manière autonome en créant des emplois en investissant dans les petites et moyennes entreprises (PME) en Afrique.

Carrière politique
Lefroy est l'un des trois conseillers conservateurs du quartier Westlands du conseil de Newcastle-under-Lyme. Lorsqu'une administration conjointe dirigée par les conservateurs et les libéraux-démocrates prend le contrôle sur les travaillistes en , il est titulaire du portefeuille des finances et de l'efficacité dans l'arrondissement.

Lefroy est le candidat officiel du Parti conservateur pour Newcastle-under-Lyme aux élections générales de 2005, perdant face au député travailliste en exercice, Paul Farrelly.

Lefroy est élu pour la première fois député de Stafford en 2010 avec une majorité de 5 460 voix et est réélu aux élections générales de 2015 avec une majorité accrue de 9 177 voix. Il ne se représente pas aux élections générales de 2019.

Au Parlement, il siège au Comité spécial pour le développement international . En 2013, Lefroy est élu président du Réseau parlementaire sur la Banque mondiale et le Fonds monétaire international. Il est membre du comité exécutif de 1922 .

Lefroy se décrit comme un " conservateur One Nation" . Il préconise un vote « Remain » pour le référendum de 2016 sur l'UE .

Vie privée
Lefroy est marié à Janet, médecin généraliste et maitre de conférences en médecine à l'Université de Keele, depuis 1985. Le couple a deux enfants, qui sont tous deux allés à l'école à Newcastle-under-Lyme.

Il est membre du Conservateur Christian Fellowship .

Références

Liens externes

Député du 57e Parlement du Royaume-Uni
Député du 56e Parlement du Royaume-Uni
Député du 55e Parlement du Royaume-Uni
Député du Parti conservateur (Royaume-Uni)
Étudiant de King's College (Cambridge)
Naissance en mai 1959

redpajama_set_name: RedPajamaWikipedia


text:
Kolusu
KOLUSU is a film produced by BLACSPICE FILMS in collaboration with Singapore Indian Theatre and Film Explorers (S.I.T.F.E). Watch this space for updates, pictures and teasers of our upcoming film!
KOLUSU is a film produced by BLACSPICE FILMS in collaboration with Singapore Indian Theatre and Film Explorers (S.I.T.F.E).[...]
Meetup #3 & Free Acting Workshop
Meetup #02 & Mobile Film Making workshop
Meetup #1
Show & Tell of PANJABOOTHANGAL performances by some groups and updates on S.I.T.F.E.'s upcoming events.
Discussion on PANJABOOTHANGAL and updates on S.I.T.F.E.'s upcoming events. (more…)
The first meetup with general public and members about S.I.T.F.E. & idea generation session
KALAI MAALAI 2017
Shakespeare's
In commemoration of Shakespeare's 400th Anniversary, S.I.T.F.E. organized this event which invited actors, writers and directors who had[...]
S.I.T.F.E CLUB event #01
S.I.T.F.E. CLUB was officially launched with a sharing by Cultural Medallion Mr KTM Iqbal. Mr Iqbal recited about[...]
Blk F #01-01 LASALLE College of the Arts 1 McNally Street Singapore 187940
Phone: (+65) 8268 6481
Email: sitfexplorers@gmail.com
Copyright © 2019 Singapore Indian Theatre & Film Explorers. All rights reserved. Web Design By De Mellows


A warm welcome will await you at Hinsley Hall in Leeds the Diocese of Leeds Conference Centre. Attractive landscaped grounds create a peaceful setting for our well appointed facilities, one and a half miles from the centre of the city, with good access by public transport.
The Centre offers a comfortable, cost-effective venue suitable for a variety of needs.
Groups and individuals of all denominations and faiths are welcome and enquiries are invited for events and training of all kinds.
Our bedrooms provide residential groups with pleasant accommodation and full en-suite facilities. The dining room seats up to 90 people and two smaller rooms are available for private dining.
From our high quality cuisine you may choose our menu for the day or plan in advance a menu of your choice. Vegetarian or special dietary needs are catered for.
The surrounding area has much to offer the visitor. The Yorkshire Dales, stately homes, ancient abbeys, art galleries and museums vie with the shopping and entertainment facilities of Leeds for your interest and enjoyment.
Our experienced and friendly staff are here to relieve you of the burden of organizing your visit. Their help and expertise will ensure a successful event and an enjoyable stay with us.
• Large conference room for up to 90 people.
• 11 other meeting rooms of various sizes.
• Library and book shop.
• Dining room for up to 90 guests.
• Bar and lounge area.
• Ample and secure free car parking.
• One and a half miles from Leeds city centre.
• Set in four acres of tranquil grounds.


Steve Quayle is an extreme right wing conspiracy theorist, pseudohistorian, religious fundamentalist, doomsday fearmonger, gold bug, and radio kookbabbler.
Quayle is an occasional guest on right wing conspiracy media, including Coast to Coast AM, Jim Bakker, Alex Jones, and TruNews.
On TruNews, he stated that President Obama accepted the Democratic presidential nomination from "Satan's throne" in 2008.
On Jim Bakker's show, Quayle claimed there is a massive conspiracy by "the global elite" to reduce the human population by 90 percent through the use of birth control, Ebola, and the Zika virus.
On Coast to Coast AM, Quayle further expanded on this theme by combining his depopulation conspiracy theory with chemtrails, biowarfare, genetic experimentation, and a secret airbase in Nevada.
Alex Jones apparently believes that Quayle is a prophet and that all his predictions have come true.
For the Bigfoot of today's bible-thumping giant aficionados, see our article on the nephilim.
""I have invested over 30 years researching the vast history of giants. It has, for the most part, been kept from the public. Proof of giants' existence — their skeletal remains — has been quickly secreted away in obscure museums, when not destroyed. Additionally, time has cloaked and sugar-coated these creatures' true perverse nature, the majority too vile, too demonic for bedtime stories. However, history is replete with their tales of unimaginable cruelty, sexual perversity, cannibalism and pagan rituals. This is only the beginning. Some things are best forgotten… or are they?
Quayle claims to be "the leading authority" on giants. Apparently, he believes that Conan the Barbarian was a giant capable of running into a herd of bison and scooping up one in his arms. His evidence for this is because the Bible said so in the book of Genesis. He also believes that the giants before the days of Noah were "very advanced" and had "supernatural" powers.
""The truth is that much of what many today believe unlikely or impossible is in fact not only possible be most likely actually happened.
Using advanced technology, the global elite can manipulate the weather and cause extended periods of drought or storm.
The Nazis didn't lose World War II and built an empire under the ice.
"Monsterous [sic] creations" are being developed with secret technology in labs around the world.
Giants, transhumanism, genetic manipulation, Bible prophecy, the end times, it's all true!
Apparently, it's all because of the Catholics. Or something.
On Coast to Coast AM Quayle called immigrants coming into the US "infectons", claiming they could be "intentionally exposed to some of the most deadly pathogens with the goal of spreading disease" as Coast to Coast put it. Nobody thought to tell him that perfectly legit businessmen returning from exotic foreign locations are every bit as much of a potential threat.
According to him, the bombardment of the US embassy in Moscow with microwaves (1953-76) was not, as reported at the time, a form of radio jamming but a successful scheme using "quantum frequencies" to project viruses through thin air. Amazing what quantum frequencies can achieve.
Quayle runs a precious metals business that panders to the paranoid, using typical scaremongering language.
↑ Rick Wiles Points To 'Game Of Thrones' Tweet To Prove Obama Is The Antichrist. Right Wing Watch, 12 May 2014.
↑ Steve Quayle: 'The Destruction Of 90 Percent Of Humanity' Imminent. Right Wing Watch, 14 September 2016.
↑ Bioweapons & Viruses/ Genetic Engineering. Coast to Coast AM radio show archives, 30 June 2014.
↑ Steve Quayle: The man who predicted it all speaks out. Infowars.com, 18 August 2016.
↑ The Truth about Giants.
↑ Consider the image on the cover of Quayle's True Legends.
↑ Steve Quayle reveals technology of the fallen. Infowars.com, 26 July 2015.
↑ Stephen Quayle, Little Creatures: The Gates of Hell Are Opening, 2015. ISBN 1495137953.
↑ Stephen Quayle, Weather Wars & Un-Natural Disasters, 2007. ISBN 0972134786.
↑ Stephen Quayle, Empire Beneath the Ice: How the Nazis Won World War II, 2015. ISBN 149513797X.
↑ Stephen Quayle, Xenogenesis: Changing Men Into Monsters, 2014. ISBN 1467576018.
↑ Stephen Quayle, Angel Wars: Past, Present and Future, 2011. ISBN 0983623902.
↑ The Unholy See. Are the forbidden secrets of the prehistoric past linked to the forthcoming events of the prophetic future? Is there a hidden hand confiscating and concealing artifacts relating to the world before the Flood of Noah and the hybrid entities that inhabited it? Are living giants still walking the earth today? Is the Vatican preparing for the arrival of "alien saviors"?
This page was last modified on 17 August 2018, at 01:05.


text:
BOOK CLUB: Every Note Played
BOOK CLUB Books POPULAR FICTION
Author: Lisa Genova
Lisa Genova is the bestselling author of Still Alice which has been made into an award winning film. It is the only Genova title that I have read but she is certainly one cemented on my watch list.
Every Note Played is an in-depth and insightful exploration of the insidious ALS, the disease at the heart of the Ice Bucket Challenge; suffered by Lou Gehrig and Stephen Hawking. ALS is a disease that doesn't discriminate, it could strike anyone.
Genova pens a heartbreaking tale of ALS when it strikes an accomplished concert pianist, whose first love has always been the piano. On tour and in the prime of his life Richard heads to the doctor for what he thinks is a bout of tendonitis, only to discover that it's the early stages of ALS.
Less than a year later and things are progressing faster than he would like. Denial is no longer an option and Richard is watching his life slip further away, and take his independence with it.
Karina is Richard's ex-wife and the mother of his child. The two have a volatile relationship and now that their daughter is away at college they don't speak at all. Karina is a piano teacher and not finding it as fulfilling as she once did but she is still paralysed by excuses and fear, afraid to pursue the career path that once excited her.
Every Note Played explores ALS and the effect it has on Richard's body, and on his mind, but it's also a story of making peace. Karina and Richard are both holding onto more than their fair share of resentment and anger about their failed marriage and they don't seem to own any of the responsibility for what went wrong.
Richard finds himself unable to live on his own and the only real option is for Karina to become his carer and have him move back into the house they once shared. Their relationship is still strained and there is a lot of resentment, living in such close quarters gives them endless opportunities to work through their issues and find forgiveness but will such strong willed people allow themselves to bend that far.
Genova pulls no punches in her stark and heartbreaking portrayal of ALS and the devastation it wreaks on bodies. She shines a light on the 24/7 nature of care required and gives a nod to some of the other high profile personalities living with ALS. This story is touching as well as devastating. The long road that wound down a lot quicker than expected and the long road to forgiveness for a passionate couple who were once so deeply in love.
All relationships were assessed and analysed as Richard became more and more trapped inside his head, being cut off from reliable communication leaves him introspective. Terminal illness can make or break a family and in this case, I think there was finally some progress made, but it was still a long time coming.
Karina and Richard are both characters who were drawn in great detail, who we got to know intimately as they wrestled with their issues. They held resentments from long before Richard's disease brought them back under the same roof but once they are back in their marital home and Karina becomes his carer they start to grow new resentments.
My favourite character in the whole story is Bill, he is one of the home health aides caring for Richard and he is the absolute embodiment of compassion. If I ever need a personal care nurse I want someone just like Bill. We learn the motivations for his chosen career and we get to know him. He is empathetic but he is also more than just a nurse. He becomes a friend but he also treats more than just the challenges Richard faces, his care encompasses the family. He is invested and makes sure that he can remain one of the carers after Richard moves out of his area.
Every Note Played is a story of finding the courage to forgive and to really live, it's about learning the peace that you can find for yourself when you offer forgiveness. It is raw, heartbreaking and sometimes hard to read but at the same time it is well worth the read. Genova has obviously done her homework, the story is well researched, beautifully written and emotional. I love that she is shining a light on tough topics and helping to bring these diseases into conversation, to make them talking points and hopefully bringing them extra attention can assist in the long term goals of treatments and cures.
Definitely well worth read, I would wholeheartedly recommend Every Note Played.
Lisa Genova can be contacted on LisaGenova.com, Twitter and Facebook.
Thanks to Simon & Schuster 30 of our Beauty and Lace Club Members will be reading Every Note Played so please be aware there may be spoilers in the comments below.
Every Note Played is published by Simon & Schuster and available now from Angus & Robertson Bookworld, Booktopia and where all good books are sold.
Blog Tour Book Review: The House of New Beginnings
BOOK CLUB: The Codebreakers
BOOK CLUB: The River Gum Cottage
Book Review: Burnt
Tags: ALS, book club, contemporary, lisa genova, POPULAR FICTION, Simon & Schuster
BOOK CLUB: Making Peace
BOOK CLUB: The Paris Seamstress
29 thoughts on "BOOK CLUB: Every Note Played"
Debbie Dye says:
Every Note Played is an emotional rollercoaster , poignant, beautifully written and gripping.
It's based around Polish immigrant Karina and her conceet pianist estranged ex-husband Richard. Their relationship was complicated…Richard cheated and Karina had her own secrets too.
Now bound together only by their college student daughter Grace, Karina learns that Richard is suffering from the debilitating and terminal condition ALS, otherwise known as Motor Neuron disease or 'What Stephen Hawking had'.
This is all the more topical as Stephen Hawking only died recently and this has brought the conversation about quality of life vs quantity to the forefront of our minds.
Karina, through misdirected guilt, pity, duty or a mixture of reasons eventually decides to become Richard's carer.
Richard's decline in functionality is all the more horrid because his career, his life, his very existance revolves around his beloved piano and his career as an acclaimed classical concert pianist.
Karina was also destined for greatness as a classical pianist, but her true love is jazz. Something Richard could never understand and a love she dissolved as a dutiful wife and mother.
I found myself constantly drawn into the debate of what would I do if I was in this situation…knowing the outcome?
And Lisa Genova's ability to weave the classical music into the text, like a constant calming accompaniment is brilliant.
I loved reading Every Note played and I love Lisa's mentions of the ALS charities at the end.
Most of us would be familiar with Stephen Hawkings journey with ALS and the devastating effect it has on ones physical body, but not the mind.
Richard, a revered and accomplished concert pianist, finds his body quickly starving away and the author, Lisa Genova, captures all emotions and rollercoaster ride that Richard experiences – from disbelief, reluctance, resentment to overcoming his pride and the heartbreak of living with this neurological disease.
Also struggling with Richards diagnosis and his aloof relationship with their daughter, is Karina, Richard's ex wife, herself a pianist but not as accomplished. Afraid of being pushed away but with no one else to care for him Karina becomes his reluctant carer along with the help of caring and compassionate Bill.
Before reading Every Note Played, I was not very familiar with ALS, also known as Lou Gehrigs Disease and it is very evident by Lisa's extensive research that this is a true to life, almost biographical novel of a once known friend. Lisa is a brilliant writer, having written the Oscar nominated 'Still Alice' and having studied a PHd in Neuroscience at college, this deeply passionate, human story is also intermingled with the actual symptoms, signs and side effects of ALS.
If you think you would enjoy a deeply touching, personal and unforgettable novel that makes you think as well as tugs at the heartstrings, give Every Note Played a read,
Every Note Played was one of the most emotional and raw books I've ever read. It was both educational, heart warming, and heart wrenching all at the same time. I didn't know anything about ALS before I read this book, but feel I have a good understanding to the horrible symptoms and decline that the sufferers and their families go through.
While I didn't like Richard as a character, I would never wish the pain and suffering he experienced on anyone. It is an eye opener that we need to put our loved ones first, as we never know what will happen. It was well written, especially the raw honesty of the emotions the family and loved ones experienced.
Thank you Beauty and Lace, and Simon & Schuster for giving me the opportunity to read and review this book.
Imogen says:
Lisa Genova's new novel Every Note Played is a moving and profound study in the hideous death sentence that is ALS and its inexorable and inescapable march on the lives of its sufferers and in turn their families and loved ones. At times almost too sad to bear, this novel explores not only the disease but the relationships of Richard and his family which are quite suddenly and forcefully brought to the forefront.
Certainly a tearjerker but also leaves the reader feeling somewhat incongruously hopeful, I will certainly be recommending this book to family and friends, Thanks to Beauty and Lace, Lisa Genova and Simon and Schuster for the opportunity to read and review Every Note Played.
alanna jane says:
i found this quite an emotional book to read as my father in law suffered with MND similar but different, and it was so very hard as a family to watch his independence fade away.
I thought it was very well written and didnt hold back what its like to suffer such horrible illnesses
Have already passed this along to other family members and i am sure it will "do the rounds"
My heart went out to Karina and felt every emotion with her.
11/10 stars
Thanks for the opportunity to read Every Note Played
What a heart wrenching storyline of the devasting ALS & its effects on everyone concerned Richard & Karina are both strong characters who although seperated come together as the disease takes its course & Richard needs a carer both interesting characters but along comes Bill a personal care nurse my favourite character
The rest I will leave for everyone who I hope get the chance to read this awe inspiring story
I highly recommend this book & thank you Lisa Genova
First up thank you Beauty and Lace and Simon and Schuster for selecting me to read this book. This is my very first book by Lisa Genova and again I am so grateful to have been chosen to read this book.
It was an emotional rollercoaster ride. I felt happiness, anger, frustration, confused and immense sadness. Before reading this book I did not know the depths of ALS my main knowledge was knowing that Stephen Hawking suffered from it. What a heartbreaking and horrible disease for anyone to suffer through not only for themselves but for their loved ones to watch them be taken away by it.
This book is a must read and I highly recommend it. Very well written and no sugar coating. Thank you Lisa for a great book.
Every Note Played is an emotional and well researched story on the degenerative disease ALS. When Richard, a concert pianist, is diagnosed with ALS he is at first in denial but as the degeneration of his muscles progresses he must face a life without his beloved piano. Genova goes through Richard's slow degeneration and explains the symptoms in a poetic rather then clinical way. The characters inner feelings are expressed with clarity and compassion. Richard and his wife are divorced and we get both sides of the story with a dual POV. Genova focuses on relationships and forgiveness, the all consuming job of caring for a terminally ill loved one and the wonderful job done by home help workers. Had me in tears. A recommended read.
This book is the first book in a long time for me, that I wasn't able to put down.
Lisa Genova takes you through the thoughts of someone who is diagnosed with ALS. Beginning with Richard who is in denial about his ALS and his wife Karina who refuses to believe that he actually is suffering from the disease. Richard who is a pianist and is known for playing at grand locations around the world has his life turned upside down when he is diagnosed with ALS.
The book takes the reader through both Richard and Karinas thought process. Richard who is coming to terms with the immediate decline in his health and Karina as the ex wife who takes it upon herself to become carer to an ex husband that she has despised for so long.
This book left me crying through the last couple chapters. Recommend it for all who will want to read it.
Every Note Played by Lisa Genova is a must read book about the devastating effects of ALS on the body and the resounding emotional turmoil. I enjoyed reading the on-going and strained relationship between Richard and Katrina and how the ravaging effects of Richard's ALS and subsequent side-effects healed their relationship. Thank you Beauty and Lace and Simon and Schuster Publishers for the opportunity to read this book and to learn and have a greater understanding of ALS.
I found Every Note Played by Lisa Genova to provide such insight into the disease ALS. It showcased not only the disease and the decline in health, but the true emotions and impact that it can have on a whole family. This novel follows the story of Richard who is a concert pianist and his ex-wife Karina, who had big dreams of being a jazz pianist but forfeited this dream early on to be a mother. The lives of Richard and Karina come together again when Richard is unable to care for himself in his own home. This is definitely a story of healing and forgiveness, and yes it is a bit of a tear jerker.
Thank you, Beauty and Lace, for the opportunity to read this book. I enjoyed learning about the disease of ALS and it has given me a lot more understanding regarding the disease.
Dale Pearce says:
Every Note Played by Lisa Genova follows the life of Richard, a concert pianist, who starts showing symptoms of ALS (Amyotrophic lateral sclerosis) or Lou Gehrig's disease.
Richard is in massive denial as he knows that he will one day no longer be able to function let alone play piano. He tells his agent that he has tendonitis so that his concerts around the world will be cancelled and as Richard reaches each milestone of losing control of his body this fabulous book follows his story.
Every Note Played shows that even in dysfunctional families there is sympathy for those that are suffering. Karina, Richard's ex-wife, selflessly opens her home to him in his hours of need and helps him through each and every decline of the disease.
As I started crying from page 65, this book was a challenge to read – can't read whilst out and about or if you know someone is coming to the house BUT it is a book that was hard to put down. If this book is made into a movie you will not get away with the small pack of tissues that fit into your handbag but will need the family size box and no sharing.
Thank you to Beauty and Lace and Simon & Schuster for allowing me to read this amazing book.
Sarah Tegerdine says:
Gosh, this book had me hooked from the 1st page, I couldn't put it down.
It was so moving and you could feel the conflict from all parties. It was artfully written, at first I thought I was going to favour 1 character over another and to my surprise I was moved by everyone. Their pain was so palpable, it caught me off guard and felt utterly absorbed by it.
I would recommend it this to anyone who is looking for a book with heart and depth!!!
Thank you so much to Simon and Schuster and Beauty and Lace for the opportunity of reading 'Every Note Played'… It's a story that left footprints….!
Richard is an accomplished concert pianist, with a history of performances all over the world. At least, he was 8 months ago. He has been diagnosed with ALS – his right arm is completely paralyzed, and he knows his left arm will be next.
Three years ago, his wife Karina took down their wedding photo from the wall. But she still hasn't been able to move on, blaming Richard and their failed marriage for not following her dream of jazz piano.
As Richard's health deteriorates and he can no longer live independently, Karina reluctantly becomes his carer, as they both try to reconcile before it's too late.
Having read some of Lisa's other books before, I had a rough idea of what to expect. What I didn't expect was to be able to vividly see, and feel, what Richard was experiencing, as if I was living it myself.
Richard and Karina are characters that I love to hate. They are both arrogant and self-absorbed, and hold only blame and anger for each other. However, I love that the characters did not change majorly throughout the book. Many books have characters starting off like this, who then become all sweet and loving, but these characters do not change so drastically. There's no real happily ever after, and I really appreciate that.
The descriptive language used in the novel really allowed me to really experience ALS in my own way. When Richard experienced difficulty swallowing or breathing, I could feel myself experiencing it too. I love reading books that allow you to be in the characters' shoes.
I'm really glad that I read this novel!


L&T Conservative Hybrid Fund Direct-Dividend quarterly is a Balanced mutual fund scheme from L&T Mutual Fund. This scheme was launched on 01 Jan 2013 and is currently managed by its fund managers Jalpan Shah and Venugopal Manghat. It has an AUM of ₹42.35 Crores and the latest NAV decalared is ₹11.544 as on 25 Apr 2019 at 9:05 pm.
L&T Conservative Hybrid Fund Direct-Dividend quarterly scheme return performance in last 1 year is 5.27%, in last 3 years is 24.34% and 60.86% since scheme launch. The min. SIP amount to invest in this scheme is ₹1000.
The scheme aims to generate monthly income with minimum investments in debt instruments to the extent of 80 percent. Equity and money market instruments can constitute a maximum of 20 per cent of the portfolio.


text:
Canadian Surface Combatant: Naval Group And Fincantieri Propose To Canada A Joint-Offer Based On The FREMM Frigate Design
The Government of Canada has declared its intention to acquire an existing and proven NATO warship design that could be readily modified to best meet the Royal Canadian Navy requirements.
Diana Shipping Inc. Announces Time Charter Contract for m/v Norfolk With SwissMarine
Diana Shipping Inc. (NYSE:DSX), (the "Company"), a global shipping company specializing in the ownership of dry bulk vessels, today announced that, through a separate wholly-owned subsidiary, it has entered into a time charter contract with SwissMarine Services S.A., Geneva, for one of its Capesize dry bulk vessels, the m/v Norfolk.
Navios Maritime Containers Inc. Announces Delivery Of The First Of Four Containerships With Period Charters
Navios Maritime Containers Inc. ("Navios Containers") (N-OTC:NMCI), a growth vehicle dedicated to the container sector, announced today that it has taken delivery of APL Denver, the first of four 2008-built Panamax containerships with period charters it has agreed to acquire.
PHOTO RELEASE–Huntington Ingalls Industries Launches National Security Cutter Midgett
Huntington Ingalls Industries' (NYSE:HII) Ingalls Shipbuilding division launched the National Security Cutter (NSC) Midgett (WMSL 757) on Wednesday. Midgett is the eighth NSC Ingalls has built for the U.S. Coast Guard. It will be christened during a ceremony on Dec. 9.
SKY Perfect JSAT And KVH To Deliver Maritime Broadband Services
KVH Industries, Inc., (Nasdaq:KVHI), today announced that it has concluded arrangements with SKY Perfect JSAT (SJC) to work together in delivering next-generation maritime broadband services.
PHOTO RELEASE–Huntington Ingalls Industries Delivers Guided Missile Destroyer Ralph Johnson (DDG 114) to U.S. Navy
Huntington Ingalls Industries' (NYSE:HII) Ingalls Shipbuilding division delivered the guided missile destroyer Ralph Johnson(DDG 114) to the U.S. Navy today with shipbuilders, ship's force and representatives of Supervisor of Shipbuilding Gulf Coast in attendance.
Global Marine Coatings Market Is Predicted To Reach A Value Of US$14.52 Bn By 2025 – Transparency Market Research
The global market for marine coatings has significantly evolved over the many centuries since ships made primarily from wood were launched and continues to evolve as shipbuilding materials span a vast array including metals, nonmetals, and manmade fibers and materials.
PHOTO RELEASE–Huntington Ingalls Industries Authenticates Keel of Guided Missile Destroyer Lenah H. Sutcliffe Higbee (DDG 123)
Huntington Ingalls Industries' (NYSE:HII) Ingalls Shipbuilding division authenticated the keel of the Arleigh Burke-class guided missile destroyer Lenah H. Sutcliffe Higbee (DDG 123) today. The ship is named in honor of the first woman to receive the Navy Cross.
PHOTO RELEASE–Huntington Ingalls Industries Christens Destroyer Delbert D. Black (DDG 119)
PASCAGOULA, Miss., Nov. 04, 2017 (GLOBE NEWSWIRE) — Huntington Ingalls Industries' (NYSE:HII) Ingalls Shipbuilding division celebrated the christening of the Arleigh Burke-class guided missile destroyer Delbert D. Black (DDG 119) today with approximately 1,200 guests in attendance.
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text:
EU net zero climate goal: momentum reduced to a footnote
Which 4 countries blocked an EU net zero emissions goal for 2050? 20 June 2019
© WWF EPO / Alex Mason
Brussels, Belgium - 20 June 2019
Today's European Council failed to deliver an EU climate neutral target for 2050. This is despite the flood of Member States voicing their support for such a target in recent days, reaching 24 in total. In the end, due to opposition from just four countries - the Czech Republic, Estonia, Hungary and Poland - the text only refers to a "climate-neutral EU", but without mentioning 2050 or any target year. It merely contains a footnote stating that the "large majority" of countries are in favour of a 2050 target.
Ester Asin, Director of WWF European Policy Office commented:
"The EU has dealt itself a devastating blow in terms of its climate leadership. It has let down all the people who have been massively calling for climate action in recent months, reducing their hopes for a climate-neutral Europe to a mere footnote.
"The 24 Member States who support a climate neutral 2050 target have failed to stick to their guns, and allowed their commitment to be watered down by just four blockers - Poland, the Czech Republic, Hungary and Estonia.
"The reference to being in line with the Paris Agreement in such a flimsy text makes a mockery of that Agreement, and should not be allowed to stand.
"A commitment to net zero emissions by 2040, and an update of the EU's 2030 climate target, must be included in the EU's updated climate pledge to the UN. We urge the Finnish EU Presidency and the new EU Commission president to help make it happen urgently."
The EU will attend the UN Secretary General's climate summit in September in New York, at which many countries are expected to bring climate pledges that have been updated since the 2015 Paris Agreement. The next official European Council is scheduled for 17-18 October.
Imke Luebbeke, Head, EU Climate and Energy Policy
iluebbeke@wwf.eu +32 2 743 88 18
Sarah Azau, Senior Communications Officer,
sazau@wwf.eu +32 473 573 137
© WWF EPO / Alex Mason Enlarge
WWF's media advisory ahead of the European Council
European Council conclusions - 20 June 2019
Scenes from the People's Climate March in Germany
© WWF Germany / Peter Jelinek Enlarge


Peru has varied landscapes: the Andes mountains, rainforest, and the plains and valleys near the coast. And Machu Picchu, the famous 15th century Incan ruins, is just one of the ancient ruins to be explored in Peru.
Below, you can find Matador's articles on aspects of life and travel in Peru like the best time to visit, volunteering, the day in the life of an expat, tube hunting in Lobitos, Peruvian drinks guides, and how to learn indigenous languages.


On the field: Hay Park claimed a 120-run win over Dalyellup Beach on Saturday. Photo: Thomas Munday.
Hay Park still remains in contention for the 2018/19 Bunbury and Districts Cricket Association premiership title.
On Saturday afternoon, the Redbacks cruised to an effortless 120-run victory over Dalyellup Beach.
In front of an enthusiastic home crowd, Hay Park opening batsman Fraser Thompson knocked 63 runs including a remarkable nine fours.
Following opener Kris Miller's dismissal, top order batsman Steven Florance made an impressive 49.
Knocking four fours and five sixes, middle order star Michael Tassone added 73 to the home side's total.
Chasing Hay Park's 6/249, Dalyellup Beach opener (52, including eight fours) gave the visitors a glimmer of hope.
The Beach Boys' middle and lower order batsmen were later dismissed mercilessly.
The Redbacks earned a bonus point for their efforts in round 15.
League leaders Eaton suffered an upset loss to third-placed Colts at the Bunbury Recreation Ground.
Eaton top order batsmen Clayton Caltsounis (24 off 68 balls) and James Hillery (37 off 71) got the team's campaign off to a cracking start.
Scott Tynan made 31, before the Beavers' middle and lower order batsmen were taken down.
Joe Barningham (collecting 3/37 from 10 overs) assisted in dismissing Eaton for 164.
During Colts' time at the crease, Eaton bowler Clint Hewson claimed 2/25 from 10.
After Jaysen Miguel's dismissal, fellow opener Jayden Goodwin slogged a respectable 72 not out in his 122 minutes with the bat.
Middle order batsmen Barningham, Murray Goodwin, Riley Miguel, and Cruize Ciallella also made double figures.
Colts reached the opposition's total with 9.2 overs to spare.
Second-placed Leschenault also picked up a bonus point on the weekend.
The side excelled in its clash with Marist at Forrest Park North, scoring a 117-run win.
Leschenault was stranded on 2/14, before captain Thomas Buchanan (28 off 40) and Jarrad Quinn (43 off 69) upped the team's run rate.
Aided by bowler Ben Shipley (4/45 from nine), the Blues managed to restrict the Green Caps to 170.
During Marist's disastrous inning, Mark Steele (14 off 37) and Cole Sawyer (22 off 55) were the only batsmen to reach double figures.
Thanks to Leschenault bowlers Dwayne Franklin (2/3 from five), Matthew Bowles (2/9 from five), and Brody D'Agostino (2/12 from six), Marist was dismissed for a measly 53.
Teams will return to the field for Round 16 on Saturday, February 9.


Incldes pressure regulator & gear reduction for engine shaft (e.g., Honda GX160 5.5 HP engine).
Performance: 6 gpm, 290 psi, 2800 rpm max. rated speed. Ports: 3/4" HB inlet, 3/8" HB outlet from pump, 5/8" HB bypass outlet from regulator.
Shaft: 3/4" hollow shaft output (gear reduced for gas engine), accepts 3/4" solid shaft. Includes control unit (9910-Kit1990) Oil-level sight glass.


Shrewsbury Town Away Tickets – On Sale!
The Club can confirm that tickets for Bradford City's first game of the 2018/19 season campaign are on sale!
The Bantams kick-off the new season against Shrewsbury Town at the Montgomery Waters Meadow on Saturday 4 August – kick-off 3:00pm.
At the moment, tickets for this game are on sale to season ticket holders only. Tickets will go on general sale from Thursday 26 July.
Supporters can purchase their tickets at the Northern Commercials Stadium Ticket Office, or online by clicking here.
Any online orders received five days or more before the game will be posted unless instructed otherwise. If any tickets are ordered less than five days before, tickets will be for collection only from The Northern Commercials Stadium.
If fans are unable to collect from the stadium, the tickets will be taken to the away stadium for collection on the match day.
If you have any questions, please call the Ticket Office on 01274 770012.


Date stamps are available in several styles and either self inking or used with an inkpad.
As well as a stamp of just the date, daters can be made in combination with your own text or image.
Office self-inking dater – metal body. A lighter alternative to the Classic line.
P700 Dater – plastic and metal body. This dater design requires a SEPARATE inkpad.
For the P700 dater, please click here for our ink options.
For daters without text there are also self inking and daters used with an inkpad.
Reiner Dater – Metal body. This is a sturdy model of dater offering a wide range of layouts from printing just the date to textplate with date and even with numbers too!
If the ??? dater or numberer design design is selected it is possible to have a 2 colour ink pad – red for the date/number and blue for your text.
To order your custom dater stamp now, click here.


text:
Q: Measure Product Theorem: may non-$\sigma$-finiteness result unique product? Let $i\in\{1,2\}$. The Measure Product Theorem states that, given the measure spaces $(X_i,\Sigma_i,\mu_i)$, there is at least one product measure $\pi$ such that $\pi(A_1\times A_2)=\mu_1(A_1)\;\mu_2(A_2)$, for $A_i\in\Sigma_i$.
It also states that if the $\mu_i$'s are $\sigma$-finite, then $\pi$ is unique.
I'd like an example of a non-$\sigma$-finite pair of measures from which, nevertheless, we only obtain one product, thus showing "if" cannot be "iff" on the paragraph above.

A: Trivial example: $X = \{x\}$ has one point, $\mu(\{x\}) = \infty$, $X_1 = X_2 = X$, and $\mu_1 = \mu_2 = \mu$.  Not $\sigma$-finite, but the unique product measure is $\lambda(\{(x,x)\}) = \infty$.

A: Take an uncountable set $X$ with counting measure defined on the power set and consider $X \times X$. Then the usual product measure and the complete locally determined product measure coincide with counting measure on the product and we conclude by the result that any measure $\lambda$ on the product $\sigma$-algebra satisfying $\lambda(A \times B) = \mu(A) \nu(B)$ for all sets $A$ and $B$ of finite measure must lie between the complete locally determined product and the usual product, as was explained in this answer.

redpajama_set_name: RedPajamaStackExchange


text:
Nevillea  es un género con dos especies de plantas herbáceas perteneciente a la familia Restionaceae. Es originario de Sudáfrica en la Provincia del Cabo.

Especies de Nevillea

Nevillea obtusissimus (Steud.) H.P.Linder, Bothalia 15: 66 (1984).
Nevillea singularis Esterh., Bothalia 15: 484 (1985).

Referencias

Enlaces externos
Imágenes en Google

Restionaceae


text:
By Sean Palmerston Featured, Reviews, Reviews - Audio October 15, 2009
Harvestman: In A Dark Tongue
By Adam Wills
Neurosis' Steve Von Till doesn't seem to know the meaning of down time. After the band's latest release Given to the Rising in 2007, SVT followed up with the incredible solo folk album A Grave is a Grim Horse in 2008, and has now released another solo venture, under the alias Harvestman.
2009's In A Dark Tongue is built on the foundations of folk, yet wanders all over the musical soundscape throughout the 12 tracks, ranging from blissful layered guitar, to pounding electronic overtones, to a Gaelic inspired John Martyn cover. However, the album flows completely naturally, so the disjointed styles don't seem out of place.
Opener "World Ash" serves as a fitting introduction – calming, and surrealistic tones set up the atmosphere perfectly for "Karlsteine", which delves into a darker state of sound, only to be once again, calmed down by "Birth-Wood Bower", reminiscent of the soundtrack to a 70's nature documentary. "By Wind and Sun" picks things up with possibly the heaviest (and grooviest) track of the album, and also the lone track containing Von Till's trademark raspy chants, which transform slowly into an expansive electronic cloud by the conclusion of the track.
Von Till then turns to some worldly inspirations, as the Asian inspired "Music of the Dark Torrent" is followed by the Gaelic folk song "Eibhli Ghail Chiuin Ni Chearbhail". "Headless Staves of Poets" is a brooding and sorrowful interlude, followed by "The Hawk of Achill", a pounding 10 minute episode of pounding drums underneath layers of electronic noise and wandering guitar. "Carved in Aspen", "Light Cycle" and "In a Dark Tongue" are drawn out, droning tracks, which leaves us with "Centre of the World", a mirror image of the opener.
In A Dark Tongue isn't your typical folk album – nor is it your typical atmospheric noise album, or drone album. It's somewhere in between them all, and it pulls it off very well. After repeated listens, I'm still not sure on where this will sit with me in the long run. It requires more attention than background music would often need… but can run long with it being your primary musical focus. But given the right setting, this could be the soundtrack for an awe-inspiring journey – I just haven't quite found it yet.
(Neurot)
Harvestmanneo-folkNeurosisNeurotSteve Von Till
Mean Streak: Metal Slave
Marduk: Wormwood
Crossfaith in Wiesbaden, 15 June 2018
The series of the toughest pits to step into for photography continues. Sweat all over the lens, intense moshing and rarely a chance to get…


text:
using System;
using System.Collections.Generic;
using System.Linq;
using System.Text;
using PetaPoco;
using Vulcano.Engine.Dominio;

namespace Vulcano.Engine {
	public class Grabador {

		public static void Guardar(IList<Resultado> resultados, Action<int, string> reporte = null) {
			var ses = NHibernateHelper.SessionFactory.OpenStatelessSession();
			var tx = ses.BeginTransaction();
			try {
				var i = 1;
				foreach (var resultado in resultados) {
					ses.Insert(resultado);
					foreach (var detalle in resultado.Detalles) {
						detalle.Padre = resultado;
						ses.Insert(detalle);
					}
					if (reporte != null)
						reporte(i, "progreso");
					i++;
				}
				if (reporte != null)
					reporte(i, "total");
				tx.Commit();
			} catch (Exception ex) {
				tx.Rollback();
				throw ex;
			} finally {
				ses.Close();
			}
		}

	}
}

redpajama_set_name: RedPajamaGithub


I'm just a college student with so many feels.
Jesus is Lord bae. I'm confused, or sleepy, all of the time.
:] Thanks - Happy Baby Jesus Day to you too~!
: ) No proublem, Screamo.
Your avatar is cute. Can I draw it?
Oh i'd love you to! Thank you so much~!
oh please Do add me as friend i'll add you too:D lol.
know what i mean xD ohey & hello i'm mafe.
MAFE? how would u prononce that? (MAY- FFF-EEE?) FAILZ.
Oh i shall my little bannana fann'a c8 (haha get it- bannana fann'a as in- FAN.
Well you know.. I just wrote what was in my.. heart.
And btw i'm Potential- Poe for short.
‹ㅑJïNxㅜㅇNㅕ› has chosen not to enable this feature.
Asylum Role play! Characters Needed!


Headquartered in Silicon Valley, CA, Proxim Wireless Corporation is the only vendor that provides secure, scalable and high-performance broadband wireless systems that can be centrally managed from end-to-end – Wi-Fi, Point-to-Point and Point-to-Multipoint 4G wireless network technologies for wireless internet, video surveillance and backhaul applications.
Proxim's end-to-end broadband wireless solutions and services have helped more than 250,000 customers around the world enable new applications, increase productivity, decrease expenses, gain operational flexibility and create new business opportunities. To date, Proxim has more than 2.5 million units shipped in the field worldwide in over 90 countries.
Proxim serves customers through a global network of distributors, value-added resellers, system integrators and original equipment manufacturers. Its product portfolio enables partners to custom-build the wireless solution that fits customers' specific needs. This broadband wireless equipment is used by enterprises, service providers, carriers, government entities, educational institutions, healthcare organizations, municipalities and other organizations that need high-performance, secure and scalable broadband wireless solutions.
Claritech has been working as a reseller of Proxim Wireless products since 2015, offering on the local market Proxim's product lines, ORiNOCO® and Tsunami®, from Point-to-Point products (high speed broadband wireless access for fixed & mobile applications) to Point-to-Multipoint (high power wireless bridges exceeding 4G speeds) and Wireless LAN Access (high capacity Wi-Fi access points).


Exhausted all of the time, feel tired but can't sleep, can't drag yourself out of bed, fall asleep after meals, brain fog, can't make it to the gym, have no energy to play with your kids, drinking energy drinks like they are going out of style, taking hormone replacement therapy to try and feel more energetic; these are all symptoms of chronic fatigue, or adrenal fatigue or adrenal burnout.
Who do you know that complains about not having enough energy or being tired all of the time?
There are millions of people out there. Know this, our natural health restoration programs help feed the body what it needs to boost it's energy and get back on track.


text:
当前位置:首页 > 留学生论文 > Essay/Assignment写作
Doctor of Business Administration:CUSTOMER EXPERIENCE AND THE IMPACT OF ITS ANTECEDENTS ON THE
CUSTOMER EXPERIENCE AND THE IMPACT OF ITS ANTECEDENTS ON THE
DIFFERENT STAGES OF CUSTOMER EXPERIENCE:A DYNAMIC APPROACH.
GRENOBLE ECOLE DE MANAGEMENT
Extended Research Proposal
Dr. XXX
1.Research background
Customer experience (CX) has become a separate offering besides the traditional product-service duopoly (Pine II, Gilmore, 1998). Companies like Walt Disney, Starbucks, Nespresso are amongst the pioneers in designing memorable customer experiences. They do not simply sell a product (e.g. coffee), they provide customers with valuable and meaningful experiences. A recent Gartner report (2014) shows that 89% of firms now expect to compete primarily on Customer Experience Management (CEM), versus 36% in 2010. This considerable increase in firms' strategic focus shows that nowadays most companies understand the importance of customer experience and that they will mainly compete on experiences. Many firms incorporate the concept and the term 'experience' even in their mission statements (e.g. Nordstrom, JetBlue).
Academic research on customer experience has been listed by the Marketing Science Institute (MSI) as the number one research priority for 2014 – 2016. In MSI's words: "Understanding and managing the customer experience is a major concern of most firms, as well as one of the cornerstones of the marketing discipline. Managing customer experience effectively is considered by most practitioners to be a critical driver of their firm's long-term success" (www.msi.org). CEM can become a key factor in building a sustainable competitive advantage and it should be conceived as a core competency (Singer, 2015) by companies that want to lay out the foundations for a sustainable business and exit the commoditization trap. Both practitioners and academics are contributing to the analysis of this new marketing construct. The challenge is and will be to ensure CEM does not remain a vague concept, defined so broadly that it becomes of little use to managers. According to Klaus (2011:6) "scholarship needs to become clearer as to its scope". The concept still presents uncertainties and challenges on whether it can actually deliver the promised benefits to companies (Palmer, 2010). There is a danger that CEM may become a rebranding of service (Lemke et al., 2010).
External and internal factors are behind the increasing interest in CEM by both practitioners and academics. Among factors external to the firm, the emergence of globalization and digitization, has contributed substantially to firms strategic shift towards customer experience. These two phenomena have generated, amongst other outcomes, a power-shift in the firm-customer relationship. Customers can now access information quickly, easily and at a very low cost. The access to information that was not readily available in the past (e.g. comparing real-time prices and features between competitors' offerings) increases the power to chose, negotiate and interact with other customers, in real-time (e.g. customer-to-customer reviews). Porter (2008) highlighted the bargaining power of customers as one of the five forces that can shape the competitive battleground. This force acquires more power with the increase in information access. In 2009 the video "United Breaks Guitars" showed to the World the opportunities and risks linked to the new inter-connected digital world. The video was posted by a Canadian band to share their real-life experience of how a guitar had been broken during a trip with United Airlines and the subsequent reaction from the airline. The song became an instant hit on iTunes and YouTube signifying success for the customer and loss for the firm (the United Airlines stock lost 10% within 4 days). The event became to symbolize the new shift in power between firms—in this case an historical American airline—and customers—a relatively unknown band, whose video has been viewed more than 15 million times to date. Conversely, also great customer experiences can be immediately shared with millions of people around the world, within a matter of seconds. TripAdvisor epitomizes this phenomenon very well. More than 200 million customer-to-customer reviews are currently shared and have the power to influence the firm-customer experience (Verhoef et al., 2009; Lemke et al., 2011). Advances in the telecommunication arena have radically changed the way people and firms relate to each other. With more sophisticated, demanding and interconnected customers, the competitive battleground for the firm has changed (Mascarenhas, 2006). On top of that, the increasing commoditization of products and services (Schmitt,1999; Shaw, 2002; Meyer and Schwarger, 2007) requires an "upgrade" of firms' offering. Pine & Gilmore (1998) have highlighted that services, like long-distance telephone services,, had increasingly become commoditized, and sold only on price. Since then, experiences have emerged as the next step in what the two authors call the progression of economic value (figure 1).
Figure 1. The Progression of Economic Value – Pine & Gilmore (1998)
Internal firm-level factors like the possible failure of Customer Relationship Management (CRM) to offer the solution to address these challenges, and re-balance the power game on the firms' side, has contributed to this strategic shift in focus towards customer experiences. Although CRM gives managers the tools to collect and analyze big amounts of data on customers' history (e.g. purchases, service requests, product returns, inquiries), CRM projects have not showed an appreciable ROI. The whole CRM approach has proved to be too invasive for the customer, without accounting for the emotional side of the relationship (Schmitt, 2003; Meyer & Schwager, 2007; Palmer, 2010). One of the first well-publicized studies about CRM, by Gartner Group in 2001 disclosed a failure rate of over 50 percent. In line with these results, a 2009 survey by Forrester found a failure rate of 47 percent (source: CRMSEARCH). CEM attempts to move beyond CRM (Homburg et al., 2015) and it requires firms to involve the whole organization, rather than mainly the customer-facing functions. CEM also requires firms to look at the total experience of the Customer with the firm's offerings from a new angle, "outside-in". Emotions are now part of the analysis too. Customer experience data aims at capturing customers' subjective thoughts and feelings about a particular company's offering and uncover the meaning behind the experience (Shaw et al., 2010).
2.Research problem and proposition
The phenomena described above has generated an increase in attention towards customer experience, both in the academic and managerial worlds. However, a gap emerges within the extant literature. A general dearth of empirical research (Lemke et al., 2010; Klaus & Kaplan, 2013; Marketing Science Institute, 2014) and, more specifically, a lack of focus on understanding how the customer's experience evolves over time (Verhoef et al., 2009; Palmer, 2010). No academic research has been produced so far, to empirically examine the evolution of the CX antecedents over the different stages of the buying process. Verhoef et al. (2009 :4) asks: "Are the determinants of customer experience – and the nature and extent of their effects – stable over time? Or, are they sensitive to changes in the internal environment (e.g., customer service) and the external environment (e.g., competition)?" It is in line with the gap and the recent literature developments that the research question has been identified: How does the impact of the relevant antecedents of customer experience change along the pre-purchase, purchase, consumption and post-purchase stages of the buying process?
By investigating this research question, we offer two main contributions to extant literature. First, we contribute to empirical research on antecedents of customer experience. The extant literature on this topic has largely been static, rather than dynamic. In this research, we study how the relationship between the various antecedents of experience "evolves" over time. We define antecedent as "a preceding event, condition or cause. Something that came before something else and may have influenced or caused it "(Merriam-Webster dictionary). A deeper understanding of the dynamic aspect of customer experience is of essence because experiences are longer (than simple service encounters, as confirmed by Klaus, Kaplan, 2001 and 2013) and involve not only functional clues, but also emotional ones (e.g. Holbrook and Hirschman, 1982; Schmitt, 1999). As Customer's emotions change over time (Magids et al., 2015; Shawn at al., 2010), we can deduct that also the entire customer's assessment of the experience evolves over the course of the CX cycle stages. As a consequence, the relevance (i.e. impact) of the multiple antecedents end up having a different weight on the overall customer experience.
Second, we also review the conceptual literature and propose a definition of Customer Experience, which attempts to identify a common denominator amongst the most relevant academic contributions. Starting with Pine II and Gilmore (1998), academics have been highlighting specific characteristics of the new construct. In table 1 we summarize all main CX definitions currently available in literature. The words in red bold are the key components that, put all together, constitute the uniqueness of the CX construct. "The customer experience can be defined as "the customer's internal cognitive and affective response to any direct and indirect interaction with a firm's product, service or part of the organization. This response is subjective and evolves over time.". This definition clarifies the conceptual differences between CX and measurements like customer satisfaction or service quality (Klaus, Kaplan, 2011, 2013; Klaus, 2015; Lemke, 2011) and between CEM and CRM (Meyer, Schwarger, 2007; Palmer, 2010; Homburg et al., 2015). These differences demarcate CX from previous marketing constructs and they will be extensively discussed in our research.
Table n.1. Definitions of Customer Experience
3. Justification for the Research
An increasing number of studies link customer experience with important marketing outcomes, like customer satisfaction, customer loyalty and word of mouth (Gentile et al., 2007; Lemke et al, 2011; Rose et al., 2011; Kim, Choi, 2013; Klaus, 2013). Companies like Nespresso and Apple, just to mention a few, have shifted their strategic focus towards customer-centric business modes, which create memorable experiences, besides great quality products. This increased focus, both on the corporate and academic stages, has obviously generated further interest in Customer Experience over the last few years. At the same time, the Marketing Science Institute (2014) admits that "there is insufficient empirically-based guidance as to best practices for customer experience management". Over the CX stages, there may be thousands of touchpoints to manage and they may depend on several factors (Garg et al., 2010), which may or may not be within the retailer's control (Verhoef et al., 2009). Also, understanding the customer experience requires academics and practitioners alike to focus beyond the firm-customer boundary, including other customers and suppliers' networks (Lemke et al., 2011). These challenges have contributed to the creation of the mentioned gap on the empirical front.
As stated, this research will specifically address the topic of the CX antecedents' evolution over the course of the buying process, which has been largely neglected in academia so far. The studies produced so far, analyze the impact of the identified factors in a static manner, that is, without considering that the relationship between those factors may evolve over the different stages of the experience. Consequently, they may end up having a different weight on the overall experience. This research, after a contribution to the conceptual discussion, aims at adding a dynamic element to the empirical analysis.
Table n.2. The Customer Experience antecedents – summary of currently available models
3.1.Managerial Implications
Firms must understand how customers' attitudes adjust over time as the concept of experience itself involves progression over time (Palmer, 2010). Executives would benefit tremendously by being able to see which antecedents of the customer experience contribute most significantly to the customer's individual and internal responses, and how the relationship between them evolves over the different stages. Managers should understand which key elements contribute to an experience and in which distinct areas (Poulsson and Kale, 2004). In practical terms, a determinant that is crucial in the pre-purchase stage (e.g. social environment or peer-to-peer reviews), may become of secondary relevance or completely irrelevant over the following stages. Considering that the length of the experience is difficult to quantify and it relies on several independent factors (e.g. type of service provided), consumers will have different needs at different stages of the relationship lifecycle (Frow, Payne, 2007), and this will influence their personal assessment (i.e. customer experience). As a result of the lack of research in this specific area, managers have received little guidance to date about how to design, manage and measure customized customer experiences, especially with regards to where in the total customer journey they should focalize their investments. This point is crucial in making sure that customer experience is not perceived as a vague concept. Many managers don't know how to link CEM initiatives to a measurable Return on Investment (ROI). More than 400 CEM executives interviewed in 2014 by the Harvard Business Review Analytic Services: although the majority agreed that firms will compete mainly on experiences, 45% of them found it difficult to tie CEM investments to outcomes. Being able to understand "what-matters-where" in the CX journey becomes paramount for managers, in order to carefully plan the required financial investments and customize memorable experiences for their customers.
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text:
Home Sheriff Question: How Long Is Sheriff Academy?
Question: How Long Is Sheriff Academy?
As such, the length of a time it takes to become a deputy sheriff can range from 14 weeks to one year.
1 How long is Sheriff Deputy Academy?
2 How do you prepare for the Sheriff Academy?
3 Do you get paid while in sheriff Academy?
4 What is the cut off age for sheriff?
5 How much does Police Academy cost?
6 Is Sheriff Academy hard?
7 Do you get paid more as a police officer with a degree?
8 What do you do in police academy?
9 Can you join the police at 40?
10 Can I become a cop with a DUI?
How long is Sheriff Deputy Academy?
Yes, the Sheriff's Academy is a twenty-two (22) week training program.
How do you prepare for the Sheriff Academy?
Get Fit: The first step in preparing for a police or sheriff's academy is improving your strength and endurance. Some include:
Obstacle Course.
Body Drag.
Fence Climb.
Wall Climb.
500 Yard Sprint.
1.5 Mile Run.
How much does Police Academy cost?
If you attend the police academy without a job offer in place, you will have to pay tuition, though you can sometimes get a partial reimbursement for tuition if you get a law enforcement job after attending the academy. The average tuition for police academy is $6,700.
You might be interested: Often asked: Sheriff Who Killed Billy The Kid?
Is Sheriff Academy hard?
This is an extremely difficult and trying six months of instruction which test recruits in every way imaginable. The college has been affiliated with the Orange County Sheriff's Department since 1970 and provides training not only in the Basic Academy but also in many other advanced officer training classes.
Do you get paid more as a police officer with a degree?
Police departments place a greater value on educated officers because of the changing nature of law enforcement. Officers with degrees will bring a diverse skillset to their department, earn a higher salary, and make themselves more eligible to further their career through promotional opportunities.
What do you do in police academy?
They learn state laws, criminal investigations, patrol procedures, firearms training, traffic control, defensive driving, self-defense, first aid and computer skills. Police academy recruits also undertake physical training and fieldwork that demonstrates their comprehension of classroom instruction.
Can you join the police at 40?
Age Requirements There's no upper age limit for applying to the police service. Candidates who have reached the age of 18 years may apply to become a police officer and can take up appointment on reaching the age of 18½.
Can I become a cop with a DUI?
Technically, even if you have a DUI you can get hired as a police officer in most states, depending on the circumstances of your arrest and court case. Therefore, if you were convicted of a felony DUI, you can't become a cop.
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text:
/*
The difference is scoping.
var is scoped to the nearest function block, and
let is scoped to the nearest enclosing block
both are global if outside any block, which can be smaller than a function block.

Also, variables declared with let are not accessible before they are declared in their enclosing block.
*/

console.log(globalVar); //'undefined' as an output in runtime
//console.log(globalLet); //ReferenceError: globalLet is not defined | terminates the application
//console.log(globalConst); //ReferenceError: globalConst is not defined | terminates the application

// Global: They are very similar when used like this outside a function block.
var globalVar = 'global var';
let globalLet = 'global let';
const globalConst = 'global const';

console.log(globalVar); // successful: globally scoped
console.log(globalLet); // successful: globally scoped

// Function: They are identical when used like this in a function block.
function varletFunction() {
    var funcScopeVar = 'function scope let'; // successful: function block scoped
    let funcScopeLet = 'function scope var'; // successful: function block scoped
}

console.log(funcScopeVar); // ReferenceError: funcScopeVar is not defined
console.log(funcScopeLet); // ReferenceError: funcScopeLet is not defined

// Block: Here is the difference! "let" is only visible in the for() loop,
//        and "var" is visible to the whole function.
function letBlock() {
    //letBlockVariable is *not* visible out here
    //console.log(letBlockVariable); //ReferenceError: letBlockVariable is not defined
    let letScope = "let scope";

    for (let letBlockVariable = 0; letBlockVariable < 5; letBlockVariable++) {
        //letBlockVariable is only visible in here (and in the for() parentheses)
        //and there is a separate (new) letBlockVariable variable for each iteration of the loop
        //Thus, it binds fresh value rather than keeping an old reference.
        //In other words, If you use let instead of var in a loop, with each iteration you get a new variable.
        //That means that you can safely use a closure inside a loop.
        //Block scope of "let" is also useful for garbage collection to reclaim memory.
        console.log(letBlockVariable);
        console.log(letScope); // output: let scope
    }

    //letBlockVariable is *not* visible out here
    //console.log(letBlockVariable); //ReferenceError: letBlockVariable is not defined
    console.log(letScope); // output: let scope
}
letBlock();

function varBlock() {
    //varBlockVariable *is* visible out here
    console.log(varBlockVariable); //undefined

    for (var varBlockVariable = 0; varBlockVariable < 5; varBlockVariable++) {
        //varBlockVariable is visible to the whole function
        console.log(varBlockVariable); //0, 1, 2, 3, 4
    }

    //varBlockVariable *is* visible out here
    console.log(varBlockVariable); //5
}
//varBlock();

// Redeclaration: You can't declare the same variable multiple times using let.
// You also can't declare a variable using let with the same identifier as another variable which was declared using var.
//let letRedeclaration = 'foo';
//let letRedeclaration = 'bar'; // SyntaxError: Identifier 'letRedeclaration' has already been declared

var varRedeclaration = 'foo';
var varRedeclaration = 'bar'; // No problem, `varRedeclaration` is replaced.
//console.log(varRedeclaration); // output: bar

/*
References:
https://stackoverflow.com/questions/762011/whats-the-difference-between-using-let-and-var-to-declare-a-variable
https://stackoverflow.com/questions/33198849/what-is-the-temporal-dead-zone
*/


AKIP1 promotes early recurrence of hepatocellular carcinoma through activating the Wnt/beta-catenin/CBP signaling pathway.
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Sirtuin-mediated deacetylation of hnRNP A1 suppresses glycolysis and growth in hepatocellular carcinoma.
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Amplification of SMYD3 promotes tumorigenicity and intrahepatic metastasis of hepatocellular carcinoma via upregulation of CDK2 and MMP2.
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Dynamic expression of ZNF382 and its tumor-suppressor role in hepatitis B virus-related hepatocellular carcinogenesis.
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Lymphoid enhancer-binding factor-1 promotes stemness and poor differentiation of hepatocellular carcinoma by directly activating the NOTCH pathway.
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Genome-wide screening identifies oncofetal lncRNA Ptn-dt promoting the proliferation of hepatocellular carcinoma cells by regulating the Ptn receptor.
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Mechanisms involved in the activation of C/EBPalpha by small activating RNA in hepatocellular carcinoma.
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Endothelial fatty liver binding protein 4: a new targetable mediator in hepatocellular carcinoma related to metabolic syndrome.
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Exosome circRNA secreted from adipocytes promotes the growth of hepatocellular carcinoma by targeting deubiquitination-related USP7.
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Hepatitis B virus X protein promotes DNA damage propagation through disruption of liver polyploidization and enhances hepatocellular carcinoma initiation.
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Indian Hedgehog links obesity to development of hepatocellular carcinoma.
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Bclaf1 promotes angiogenesis by regulating HIF-1alpha transcription in hepatocellular carcinoma.
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Forcing ATGL expression in hepatocarcinoma cells imposes glycolytic rewiring through PPAR-alpha/p300-mediated acetylation of p53.
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Hypoxia-induced TUFT1 promotes the growth and metastasis of hepatocellular carcinoma by activating the Ca(2+)/PI3K/AKT pathway.
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KIFC1 regulated by miR-532-3p promotes epithelial-to-mesenchymal transition and metastasis of hepatocellular carcinoma via gankyrin/AKT signaling.
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Identification of UAP1L1 as a critical factor for protein O-GlcNAcylation and cell proliferation in human hepatoma cells.
Oncogene. 2018 Aug 10. pii: 10.1038/s41388-018-0442.
Poly(ethylene glycol)-poly(lysine) block copolymer-ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells.
Oncogene. 2018 Aug 8. pii: 10.1038/s41388-018-0406.
Hsp90beta promotes aggressive vasculogenic mimicry via epithelial-mesenchymal transition in hepatocellular carcinoma.
Oncogene. 2018 Aug 7. pii: 10.1038/s41388-018-0428.
PTBP3 splicing factor promotes hepatocellular carcinoma by destroying the splicing balance of NEAT1 and pre-miR-612.
Oncogene. 2018 Aug 1. pii: 10.1038/s41388-018-0416.
Recapitulation of pharmacogenomic data reveals that invalidation of SULF2 enhance sorafenib susceptibility in liver cancer.
PSTPIP2 connects DNA methylation to macrophage polarization in CCL4-induced mouse model of hepatic fibrosis.
Oncogene. 2018 Jul 11. pii: 10.1038/s41388-018-0383.
Collagen IV-conveyed signals can regulate chemokine production and promote liver metastasis.
SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells.
Oncogene. 2018 Jun 1. pii: 10.1038/s41388-018-0335.
Gene activation of CEBPA using saRNA: preclinical studies of the first in human saRNA drug candidate for liver cancer.
LncFZD6 initiates Wnt/beta-catenin and liver TIC self-renewal through BRG1-mediated FZD6 transcriptional activation.
Tumor-derived exosomes promote tumor self-seeding in hepatocellular carcinoma by transferring miRNA-25-5p to enhance cell motility.
Oncogene. 2018 May 22. pii: 10.1038/s41388-018-0309.
NUDT21 negatively regulates PSMB2 and CXXC5 by alternative polyadenylation and contributes to hepatocellular carcinoma suppression.
Oncogene. 2018 May 21. pii: 10.1038/s41388-018-0280.
Circulating-free tumour DNA and the promise of disease phenotyping in hepatocellular carcinoma.
Oncogene. 2018 May 14. pii: 10.1038/s41388-018-0262.
PARP10 suppresses tumor metastasis through regulation of Aurora A activity.
The Rbm38-p63 feedback loop is critical for tumor suppression and longevity.
Tumor cell-intrinsic Tim-3 promotes liver cancer via NF-kappaB/IL-6/STAT3 axis.
A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma.
Oncogene. 2018 Apr 9. pii: 10.1038/s41388-018-0206.
Stress-induced phosphoprotein 1 mediates hepatocellular carcinoma metastasis after insufficient radiofrequency ablation.
Oncogene. 2018 Mar 21. pii: 10.1038/s41388-018-0169.
Mutant KRAS promotes liver metastasis of colorectal cancer, in part, by upregulating the MEK-Sp1-DNMT1-miR-137-YB-1-IGF-IR signaling pathway.
Oncogene. 2018 Mar 21. pii: 10.1038/s41388-018-0222.
Loss of Cyclin E1 attenuates hepatitis and hepatocarcinogenesis in a mouse model of chronic liver injury.
Oncogene. 2018 Mar 19. pii: 10.1038/s41388-018-0181.
Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice.
Oncogene. 2018 Mar 16. pii: 10.1038/s41388-018-0188.
USP27-mediated Cyclin E stabilization drives cell cycle progression and hepatocellular tumorigenesis.
Oncogene. 2018 Mar 2. pii: 10.1038/s41388-018-0137.
DDIAS suppresses TRAIL-mediated apoptosis by inhibiting DISC formation and destabilizing caspase-8 in cancer cells.
FoxO1 is a regulator of MHC-II expression and anti-tumor effect of tumor-associated macrophages.
Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth.
Alu RNA accumulation induces epithelial-to-mesenchymal transition by modulating miR-566 and is associated with cancer progression.
miR-139-5p inhibits aerobic glycolysis, cell proliferation, migration, and invasion in hepatocellular carcinoma via a reciprocal regulatory interaction with ETS1.
Oncogene. 2018 Jan 16. pii: 10.1038/s41388-017-0057.
Oncogene. 2018 Jan 16. pii: 10.1038/s41388-017-0070.
Ribosomal protein S15a promotes tumor angiogenesis via enhancing Wnt/beta-catenin-induced FGF18 expression in hepatocellular carcinoma.
Oncogene. 2017 Dec 15. pii: 10.1038/s41388-017-0017.
Murine stroma adopts a human-like metabolic phenotype in the PDX model of colorectal cancer and liver metastases.
Oncogene. 2017 Dec 15. pii: 10.1038/s41388-017-0018.
Reticulocalbin-2 enhances hepatocellular carcinoma proliferation via modulating the EGFR-ERK pathway.
Wnt/beta-catenin activation and macrophage induction during liver cancer development following steatosis.
Intestinal cancer progression by mutant p53 through the acquisition of invasiveness associated with complex glandular formation.
TRIM31 is upregulated in hepatocellular carcinoma and promotes disease progression by inducing ubiquitination of TSC1-TSC2 complex.
Ribosomal proteins: insight into molecular roles and functions in hepatocellular carcinoma.
Oncogene. 2017 Sep 25. doi: 10.1038/onc.2017.
Myc target gene, long intergenic noncoding RNA, Linc00176 in hepatocellular carcinoma regulates cell cycle and cell survival by titrating tumor suppressor microRNAs.
Oncogene. 2017 Aug 28. doi: 10.1038/onc.2017.
Mitochondrial elongation-mediated glucose metabolism reprogramming is essential for tumour cell survival during energy stress.
Angiomotin-like 2 interacts with and negatively regulates AKT.
Autophagy-dependent generation of Axin2+ cancer stem-like cells promotes hepatocarcinogenesis in liver cirrhosis.
Oncogene. 2017 Aug 7. doi: 10.1038/onc.2017.
The PDGFRalpha-laminin B1-keratin 19 cascade drives tumor progression at the invasive front of human hepatocellular carcinoma.
Transcription factor SPZ1 promotes TWIST-mediated epithelial-mesenchymal transition and oncogenesis in human liver cancer.
SHP-1 is a negative regulator of epithelial-mesenchymal transition in hepatocellular carcinoma.
LncRNA HULC triggers autophagy via stabilizing Sirt1 and attenuates the chemosensitivity of HCC cells.
Critical role of Myc activation in mouse hepatocarcinogenesis induced by the activation of AKT and RAS pathways.
Oncogene. 2017 May 8. doi: 10.1038/onc.2017.
Hepatic cyclooxygenase-2 overexpression induced spontaneous hepatocellular carcinoma formation in mice.
Oncogene. 2017 Mar 27. doi: 10.1038/onc.2017.
Oncogene. 2017 Mar 20. doi: 10.1038/onc.2017.
The anti-diabetic drug exenatide, a glucagon-like peptide-1 receptor agonist, counteracts hepatocarcinogenesis through cAMP-PKA-EGFR-STAT3 axis.
The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition.
A point mutation in the extracellular domain of L1 blocks its capacity to confer metastasis in colon cancer cells via CD10.
Oncogene. 2016 Sep 19. doi: 10.1038/onc.2016.


text:
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Home » World News » Pentagon blocks top spy briefings for Biden transition team
Pentagon blocks top spy briefings for Biden transition team
Washington: The Trump administration has refused to allow members of President-elect Joe Biden's transition team to meet with officials at intelligence agencies that are controlled by the Pentagon, undermining prospects for a smooth transfer of power.
The impasse has prevented the Biden team from engaging with leaders at the National Security Agency, the Defence Intelligence Agency and other military-run spy services with classified budgets and global espionage platforms.
The Defence Department rejected requests from the Biden team this week, officials said, despite a General Services Administration decision on November 23 that cleared the way for federal agencies to meet with representatives of the incoming administration.
President Donald Trump has said he would leave the White House if the Electoral College cast votes for Biden. Credit:AP
On Saturday afternoon (ADST) California certified its presidential election and appointed 55 electors pledged to vote for Democrat Joe Biden, officially handing him the Electoral College majority needed to win the White House. The members of the College will cast votes on December 14 – normally a technicality, but outgoing President Donald Trump, who disputes the result and makes false claims of electoral fraud, has said he will leave the White House if the college ratifies the results.
The rejections came even as Biden advisers spent much of this week meeting with officials at the Office of the Director of National Intelligence and the CIA, agencies that are part of the US intelligence community but independent of the Defence Department.
Sue Gough, a Defence Department spokeswoman, said Friday that the Biden team "has not been denied any access". In what officials in the Biden camp interpreted as a change in the Pentagon position, she said the requested meetings could take place as early as next week.
By then, Biden advisers will have waited more than a month since the election to have meaningful contact with intelligence agencies that have multibillion-dollar budgets, satellite networks that circle the planet and vast surveillance authorities.
The delays have added to the unprecedented tensions surrounding the transition, fueled by a President who refuses to concede that he lost the election and spent much of his tenure accusing the nation's spy agencies of disloyalty to him.
A spokesman for the Biden transition team declined to comment, as did officials from the NSA and DIA.
The Pentagon has been in significant turmoil since the election. Acting secretary of defence Christopher Miller was installed last month after President Donald Trump fired Mark Esper, his Pentagon chief.
Current and former officials, who spoke on the condition of anonymity to discuss a sensitive matter, said the delays have impaired the Biden team's ability to get up to speed on espionage operations against Russia, China, Iran and other US adversaries.
The inability to meet with the NSA was described as particularly worrisome. The agency is the largest US intelligence service and its eavesdropping capabilities have been a critical source of intelligence on threats as varied as weapons proliferation and foreign interference in elections.
Officials said that rejections relayed this week to the Biden team cited seemingly petty procedural barriers.
One person said the Pentagon had asked repeatedly for rosters of those who would take part in a visit, lists of topics and estimates of time to be allotted – information that in some cases had been provided at the outset.
"If they were in a cooperative mood, none of this would be happening," said another person with knowledge of the interactions.
Pentagon officials in turn blamed Biden advisers. One defence official, who spoke on the condition of anonymity, citing the sensitivity of the subject, said that Biden transition officials had improperly contacted agencies directly to arrange visits and briefings and were told that they instead needed to submit requests to the Pentagon.
The result has been an awkward standoff in which former officials were spurned by agencies they formerly helped run. Among those ex-officials is Vincent Stewart, a retired three-star US Marine Corps general who previously served as Defence Intelligence Agency director and is a leading member of the Biden intelligence transition team.
Other spy agencies have been far more receptive. At the CIA, the Biden transition team has been granted extensive access to senior officials, computer equipment connected to the agency's classified systems, and office space at Scattergood, a historic homestead on the CIA compound often used for entertaining VIPs.
Biden recently named Avril Haines, a former top White House official and deputy director of the CIA, as his nominee to become director of national intelligence. Biden has made no other announcements about his intelligence team, but former deputy CIA director David Cohen is seen as a leading candidate to become director of that agency.
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Understand the election result and its aftermath with expert analysis from US correspondent Matthew Knott. Sign up to The Sydney Morning Herald's newsletter here, The Age's here, Brisbane Times' here and WAtoday's here.
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Home News Online First Mulgrave partnering with legion to upgrade town cenotaph
Mulgrave partnering with legion to upgrade town cenotaph
Drake Lowthers
MULGRAVE: The Town of Mulgrave is assisting the Royal Canadian Legion in making repairs and upgrades to the town's cenotaph.
During their regular monthly council meeting on Jan. 4, councillors passed a motion to financially support the legion's plan to upgrade the cenotaph, which is located in front of the former Mulgrave Memorial Education Centre, which also serves as the location of the town office.
Mayor Ron Chisholm said the cenotaph was in need of upgrades since it stands in front of the former school, and Remembrance Day ceremonies are always held there.
"A donation was asked for from the legion, and council talked it over," Chisholm said. "One thing is the legion never comes to us for money, they never ask us for money."
Councillors committed to fund up to 50 per cent of the estimated $4,772 cost of the project.
The mayor suggested there's really not a better cause to support, because it's paying respect to the people who served the country.
"It was a consensus that we donate and make the upgrades to the cenotaph," Chisholm said. "It hasn't had anything done to it in how long – nobody seems to know – and it's starting to look the wear."
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Q: scaling a discord bot to potentially 100k plus concurrent users So currently I'm struggling to find an efficient way to scale a discord bot written in node.It currently has music capabilities and over 100 chat commands plus moderation features. I'm in talks with large scale partnered discord servers to put my bot on their server but don't have a clue how id scale to that number and beyond.
Any Help would be appreciated <3 (also my 1st post so pls be gentle lol)


As part of the series of sessions which complement the Junior Performance land and water sessions, Stratford upon Avon Boat Club Junior 16 and 17 year squads played host to a special guest Flo Pickles. Flo started rowing as a junior at Evesham Rowing Club and her talk took the juniors on her journey to date. A move to Gloucester Hartpury attending the British Rowing World Class Start Programme gave Flo the opportunity to push herself in order to develop into the high performance athlete she is today.
Flo was a member of a crew who made history by becoming the first to win at rowing's premier event Henley Royal Regatta taking gold in the Diamond Jubilee Challenge Cup in 2014 and subsequently retaining their title in 2015. Following on from this success, Flo represented Team GB U23's through 2016 and 2017. During 2017 she competed in The Boat Race for Oxford. Flo is currently training as a lightweight at Reading Rowing Club taking part in the GB Rowing selection programme and setting her goals on achieving selection for the 2019 World Rowing Championship to be held in Ottensheim Austria, cumulating in the ultimate honour of representing Great Britain at the Tokyo Games in 2020.
Listening intently to Flo, the Junior Squad began to realise that Flo was no different to them and that setting their sights on rowing on the world stage resulting in a medal is within everyone's grasp and it takes dedication to training and time management through exam years in order to keep all on track through thick and thin in the quest for success.