People practicing Centering Prayer speak of experiencing a sense of peace. Can you please comment?
I've been doing Centering Prayer faithfully for over 20 years. Now I rarely read, haven't been to a retreat in 5-10 years, etc. Why?
I am reading all I can about the process...as well as doing it twice daily.. I have examined closely the "contemplative attitudes" such as opening/gentleness/simplicity etc.... is it ok ,i.e. is it part of the prayer, to refresh the memory of eight contemplative attitudes at the front end of the process?
I had been practicing Centering Prayer since 2008. But for the past year it seems the interest to do it has died. I would rather say the rosary or chaplet of Divine Mercy. Please help me, how can I start again?
I have used the sacred word and the sacred breath at different times in my practice of centering prayer. But often I am more aware of my pulse than my breath, and have used "the sacred pulse" in my practice. Is there anything wrong with this? Have other people found this helpful?
I have been doing centering prayer faithfully for a number of years. However, I am still operating on the surface, as a beginner.
Q: During this time when giving has so much to do with emptying shelves and wallets, what is the contemplative dimension of giving?
I am a Christian contemplative, but find myself increasingly drawn to Buddhist meditation, but am afraid that I am deserting God as there is no emphasis on God in this Atisha Kadampa school. Would it be advisable to attend these classes or do you think it may harm my Christian walk?
Q: The active prayer is my daily "go to" practice along with Centering Prayer. Can you please clarify the differences and similarities between receptive and active contemplative practices, and how they can complement each other? Can the active prayer actually become a receptive practice?
I just read Fr. Keating's Open Mind, Open Heart book. What should I do during the night, while lying in bed, and I find myself with a bunch of general thoughts going on, as well as "engaged" thoughts? I tried using a sacred word when I found myself with an engaged thought, but then the action(s) made me more awake, and I was up for an hour or more trying to fall back to sleep.


text:
U®AIDE
U®Blog
U®NEWS
Migration and a Platform for Action, Change and Transformation
This week several of my colleagues left for New York to attend a number of key-gatherings in an attempt to sustain the momentum of last years gatherings where new agreements were reached on how to deal with disasters (Sendai), climate change (Paris) and bring about sustainable development (New York).
The UN Summit for Refugees and Migrants that was held on the 19th tilts the landscape and yields yet another declaration: The New York Declaration. Already referenced as a land-mark shift towards the modernization of refugee and migration law. The Secretary General also launched a new campaign: "Together - Respect, Safety and Dignity for All" which he must have taken off our walls at the CARE office. It should all culminate in a new conference in 2018. Today the initiative was followed by a conference entitled "Large movements of refugees and migrants: Global challenge, regional responses, comprehensive strategy" organized by Italy. Italy has also been the initiator of another Global Compact on Migration feeling the pressure head on.
Frederica Mogherini, the EU foreign secretary, informed the audience about a new External Investment Plan from the EU to combat illigal trafficking of people. It mobilizes 44 billion euro to accompany private investors in fragile states and to foster economies in these countries supporting infrastructure, market development and small and medium enterprise development linked to job creation. All linked to the sustainable development goals of course. Resources for this investment plan have already been allocated. The Dutch Minister of Foreign Affairs Bert Koenders was appreciated for his effort to kick start this initiative. Mogherini was only quick to state that saving lives has to be prioritized. And here is where I am 'missing the boat'. Are we saving lives by investing in Africa? Of course investment is needed to address root causes, but also aid is needed. Getting entrepreneurs responsibly invest in Africa still remains a challenge, certainly in fragile contexts and even in seemingly less fragile contexts as witnessed by recent events in Ethiopia with attacks on foreign businesses.
Tomorrow another initiative will be launched by the Secretary General: "Platform for Action Change and Transformation" that provides for the implementation of the commitments made at the World Humanitarian Summit in Istanbul, earlier this year. With the impressive list of declarations, initiatives, compacts and conferences and the number of previous commitments referenced in paragraph 1.19 of the New York Declaration, you would agree with the Dutch vice-Minister Andre Haspels echoing the speech of his Minister Koenders today: "let's turn intentions into actions", something the Secretary General also must have thought after the Istanbul World Humanitarian Summit. John Mitchell of ALNAP rightly referred to this phenomenon as a commitment gridlock calling for some concerted action. However, also today budget discussions took place in The Hague in the Netherlands. They show a grim political reality in terms of readiness of the Dutch to pledge towards an unambivalent aid and investment programs. Instead a 0.5 billion budget cut in humanitarian aid appeared in the proposed budget. Some real transformation is needed in Dutch politics.
(below the WHS framework with 24 shifts/changes in direction proposed - also check out the Sustainable Development Knowledge Platform on the status of various UN processes)
My name is Reinier van Hoffen, founder of URAIDE.
I write this blog on space for civil society in my own capacity as public and social intrapreneur, having contributed over 15 years to the strengthening of civil society in various countries.
Disclaimer: The content of this blog does not reflect in any way the position or opinion of my current employer, the Ministry of Foreign Affairs of the Netherlands.
Book your room through Airbnb using this link. It will save my organization Tear some funds that can be used to fight poverty.
U®Books
God is een Vluchteling van David Dessin
Homo Deus (from the author of Sapiens)
Report of the World Humanitarian Summit in Istanbul, May 2016
A critical review of the operations of one of the Netherland's biggest corporates in Africa (in Dutch).
Book by Chiku Malanga, partner of URAIDE
MDG Report 2014
by Mariana Mazzucato, Professor Economics of Innovation at Sussex
IOB literature review of PPPs
Click here for a summary.
Also find the text of a lecture Dr. Achterhuis held at the 2012 Bilderberg conference.
M-F: 4pm - 5pm
info@uraide.nl

redpajama_set_name: RedPajamaCommonCrawl


text:
Tour de Feminin – O cenu Českého Švýcarska (Tour de Feminin – Krásná Lípa) is a women's staged cycle race which takes place in the Czech Republic and is rate by the UCI as a 2.2 race.

Honours

References

International cycle races hosted by the Czech Republic
Women's road bicycle races

redpajama_set_name: RedPajamaWikipedia


these kinds of things ALWAYS happen to me.
One of my new favorite games to play is to guess a stranger's name. My friends don't remember this, but while in Chicago we dubbed a random guy on the street "Mark Zuckerberg" (I guess the nerd-y look and curly blonde hair are in these days) and he decided that we all looked like "Mindy"s.
All that to say that I want you to play my game with me.
So, readers, what do you think? What's his name? What's his story? Why was he sending a picture of himself in a white t-shirt and coke boxers? What's with his face?
*I added the face. I decided this guy didn't deserve to be completely humiliated. Although it would have been a better story if it came with his face like that.


text:
Q: SocketIO Not Emitting an Action in React The Goal
I am looking for numerous users to sign into a game room, such as game/#####. When a user hits that url, their user object is created and shared to the state for any other user in that room to view.
The Problem
In componentDidMount I call my Socket api function and pass in the userObj and room value. This information makes it to the api function, and then to the server listener as well. However, when the server emits the join room event, the frontend doesn't seem to hear it and respond by updating the state.game.users object with the new user.
The Code
server.js
var app = require('express')();
var server = require('http').Server(app);
var io = require('socket.io')(server);

server.listen(8000);

io.on('connection', function (socket) {
  socket.on('join room', (userObj, room) => {
    socket.join(room).emit('join room', userObj);
  });

  socket.on('join chat', (msgObj, room) => {
    socket.in(room).emit('join chat', msgObj);
  });

  socket.on('chat message', (msgObj, room) => {
    socket.in(room).emit('chat message', msgObj);
  });
});

api.js
import io from 'socket.io-client';
const socket = io.connect('http://localhost:8000');

export const joinRoom = (userObj, room) => {
  socket.emit('join room', userObj, room);
}

export const joinChat = (msgObj, room) => {
  socket.emit('join chat', msgObj, room);
}

export const chatMessage = (msgObj, room) => {
  socket.emit('chat message', msgObj, room);
}

component
import { joinRoom, joinChat, chatMessage } from './../../api';

class GameBoard extends Component {
  constructor(props) {
    super(props);
    this.state = {
      loading: true,
      game: {
        id: props.match.params.gameid,
        users: {},
        messages: []
      }
    };

    this.socket = io('http://localhost:8000');

    this.postUsername = this.postUsername.bind(this);
    this.getBoardValues = this.getBoardValues.bind(this);
    this.buildUserData = this.buildUserData.bind(this);
  }

  componentDidMount() {
    this.socket.on('join room', (userObj) => {
      this.postUser(userObj);
    });

    this.socket.on('join chat', (msgObj) => {
      this.postMessage(msgObj);
    });

    this.socket.on('chat message', (msgObj) => {
      this.postMessage(msgObj);
    });

    this.socket.on('connect', () => {
      joinRoom(this.buildUserData(), this.state.game.id);
    });
  }

  postUser(userObj) {
    const game = this.state.game;
    game.users[userObj.id] = userObj;
    this.setState({ game });
  }
...

Repo
https://github.com/yuschick/horror-bingo

A: I think the problem is in this.socket = io('http://localhost:8000');. It means you create another connection to your server with a new socket. So when you emit a new event from server, your socket in the component cannot receive it because it has a different socket.
You can export const socket = io.connect('http://localhost:8000');, import it into your component and use it socket.on ...
In case you want to emit an event to another connected socket, you can use socket.broadcast.emit or io.emit. You can check the cheat sheet here https://socket.io/docs/emit-cheatsheet/. For example:
io.on('connection', function (socket) {
    socket.on('join room', (userObj, room) => {
        socket.join(room).emit('join room', userObj); \\<-- this will only let the socket from front end which emit 'join room' receive event

        socket.broadcast.to(room).emit(`join room', userObj); \\<-- this will let all socket from front end(in the same room) receive 'join room' event except the one which emit.
    });

    socket.on('join chat', (msgObj, room) => {
        socket.in(room).emit('join chat', msgObj);
    });

    socket.on('chat message', (msgObj, room) => {
        socket.in(room).emit('chat message', msgObj);
    });
});

redpajama_set_name: RedPajamaStackExchange


text:
The ALS Society of Canada is committed to:
Support research towards a cure for ALS.
Support provincial ALS societies in their provision of quality care for persons living with ALS.
Build public awareness of ALS and its impact.
Information: 1-800-267-4257 or http://www.als.ca
The Alzheimer Society of Canada works to alleviate the personal and social consequences of Alzheimer's disease, and to promote research aimed at discovering its cause and cure. Half a million Canadians are living with Alzheimer's disease or related dementias, and that number could increase by 50% in as little as 5 years.
Information: 1-800-616-8816 or http://www.alzheimer.ca
The Arthritis Society
The Arthritis Society is a national health charity, fueled by donors and volunteers, with a vision to live in a world where people can be free from the devastating effects that arthritis can have on lives. The Arthritis Society began nearly 70 years ago with one very clear goal; to alleviate the suffering of people crippled by arthritis. Today we bring that passion to communities across Canada. We are proud to have the trust and support of donors and sponsors who provide the funding capacity to invest in cutting-edge research, proactive advocacy and innovative solutions that will deliver better health outcomes and an improved quality of life for people affected by arthritis. That support has resulted in broad educational outreach to people living with arthritis and over $200M invested, the largest source of charitable arthritis research funding.
Information: 1-800-321-1433 or http://www.arthritis.ca
Asthma Canada
Asthma Canada (AC) is a national charitable volunteer-supported organization solely devoted to enhancing the quality of life and health for people living with Asthma, Associated Allergies and COPD through education and research. Since its inception in 1974, the AC provides a variety of asthma education and awareness programs, funds many research projects (to gain a better understanding of the disease and how it can be better managed) and has gained a reputation for providing high quality Asthma education and information to Canadian asthma consumers.
Information: 1-866-787-4050 or http://www.asthma.ca
The Canadian Cancer Society is a community-based organization of volunteers whose mission is the eradication of cancer and enhancing the quality of life of people living with cancer. The Society funds medical research, patient services and public education. One in three Canadians will develop some form of cancer in his or her lifetime.
Information: 1-888-939-3333 or http://www.cancer.ca
Canadian Hospice Palliative Care Association
The Canadian Hospice Palliative Care Association (CHPCA) is the national voice for Hospice Palliative Care in Canada. Advancing and advocating for quality end-of-life/hospice palliative care in Canada, its work includes public policy, public education and awareness. Established in 1991, its volunteer Board of Directors is composed of hospice palliative care workers and volunteers from Canadian provinces and territories as well as members-at-large.
Information: 1-800-668-2785 or http://www.chpca.net
Canadian Liver Foundation
Over 3 million Canadians are affected by liver disease and countless more are at risk of developing liver disease during their lifetime. The Canadian Liver Foundation (CLF) represents the liver health interests of all Canadians by supporting research, public and professional education and advocating for better prevention, diagnosis and treatment. Through our LIVERight initiative, the CLF is striving to reduce the incidence of preventable forms of liver disease by raising awareness of risk factors and providing practical tools and information to help Canadians safeguard their liver health in daily life.
Information: 1-800-563-5483 or http://www.liver.ca
Canadian Orthopaedic Foundation
Founded in 1965, the Canadian Orthopaedic Foundation is Canada's only charity dedicated solely to helping people maintain and restore their bone and joint health. The Foundation's resources are available anywhere in Canada - in hard copy through health care professionals, by mail, in volunteer peer support by phone through Ortho Connect, and direct-to-patient via the Internet.
Information: 1-800-461-3639 or www.whenithurtstomove.org
Crohn's and Colitis Canada
Crohn's and Colitis Canada is the only national, volunteer-based charity focused on finding the cures for Crohn's disease and ulcerative colitis and improving the lives of children and adults affected by these diseases. We are one of the top two health charity funders of Crohn's and colitis research in the world, investing over $94 million in research to date. We are transforming the lives of people affected by Crohn's and colitis (the two main forms of inflammatory bowel disease) through research, patient programs, advocacy, and awareness. Our Crohn's & Colitis – Make it stop. For life. Campaign will raise $100 million by 2020 to advance our mission.
Information: 1-800-387-1479 or http://www.crohnsandcolitis.ca/
Cystic Fibrosis Canada
Cystic Fibrosis Canada is dedicated to finding a cure or control for cystic fibrosis CF, an inherited, fatal disorder affecting the respiratory, digestive and reproductive systems. Cystic Fibrosis Canada's programs have contributed to dramatic improvements in survival of Canadians with CF. In the 1960s, most children with cystic fibrosis did not live long enough to attend kindergarten; today, half of all Canadians with CF are expected to live into their 40s and beyond.
Information: 1-800-378-2233 or http://www.cysticfibrosis.ca
Diabetes Canada is a volunteer-based organization promoting the health of Canadians through diabetes research, education, service and advocacy. Diabetes can slowly damage blood vessels in the body, resulting in serious complications, such as heart disease, blindness, kidney disease, and peripheral nerve diseases. Over nine million Canadians are living with diabetes or pre diabetes.
Information: 1-800-226-8464 or http://www.diabetes.ca
The Foundation Fighting Blindness Canada
The Foundation Fighting Blindness is Canada's largest charity for sight-saving research and has contributed over $23 million to find the causes, treatments and cures for retinitis pigmentosa, macular degeneration and related blinding eye diseases. You'll see: results thanks to Foundation funded discoveries, made possible by its generous donors. The Foundation is also known by its signature events: Comic Vision, Cycle for Sight, Ride for Sight, and Vision Quest.
Information: 1-800-461-3331 or http://www.ffb.ca/ for the latest in vision research.
The Heart and Stroke Foundation is dedicated to reducing the incidence of disability and death resulting from heart disease and stroke. It is estimated that 40 per cent of Canadians will be affected by heart disease or stroke. The Foundation works to reduce this number through research, education and the promotion of healthy lifestyles.
Information: 1-888-473-4636 or http://www.heartandstroke.ca/
Hope Air is the unique charity that arranges free flights for low-income Canadians who must travel to specialized healthcare. We serve all ages, with all illnesses, from all across Canada.
Information: 1-877-346-HOPE (4673) or http://hopeair.ca/
The Huntington Society of Canada is a national network of volunteers and professionals united in the fight against Huntington disease (HD) since 1973. The Society maximizes the quality of life for people living with HD by delivering services; enabling others to understand the disease; and furthering research into treatments to slow and prevent Huntington disease.
Information: 1-800-998-7398 or http://www.huntingtonsociety.ca
Hypertension Canada
Hypertension Canada is Canada's only national non-profit organization dedicated solely to the prevention and control of hypertension and its complications. An estimated 7.5 million Canadians live with hypertension, a leading risk factor for heart attacks, strokes, kidney disease and dementia. Powered by a professional volunteer network of the leading multidisciplinary experts in hypertension, we pursue our mission through the advancement of research, professional and public education, and advocacy for healthy environments so that Canadians will have the best managed blood pressure in the world.
Information: (905) 943-9400 or visit hypertension.ca
Kidney Cancer Canada
Kidney Cancer Canada was formed in 2006 by patients for patients. We are the only Canadian charitable support and advocacy organization focused exclusively on kidney cancer. Our mission is to improve the lives of those affected by kidney cancer across Canada. Working closely with patients, caregivers, doctors, researchers and leading experts across the country we provide a lifeline for patients and families touched by this disease by providing information and support – advocating for access to quality care and necessary treatments – promoting and supporting vital research that will help prevent and treat kidney cancer. Join the Kidney Cancer Canada community and get the support, resources and help you need.
Information: 1-866-598-7166 or http://www.kidneycancercanada.ca
The Kidney Foundation of Canada
The Kidney Foundation of Canada is the national volunteer organization committed to reducing the burden of kidney disease through:
funding and stimulating innovative research;
providing education and support;
promoting access to high quality healthcare; and
increasing public awareness and commitment to advancing kidney health and organ donation
Since 1964, our fundraising campaigns have allowed us to contribute millions of dollars to research, and to provide services to individuals living with chronic kidney disease and related conditions.
Information: 1-800-361-7494 or http://www.kidney.ca
The Lung Association
For over 100 years, The Canadian Lung Association has been dedicated to its mission of promoting and improving lung health for all Canadians. A non-profit and volunteer-based health charity, The Lung Association depends on donations from the public to support lung health research, education, prevention and advocacy.
Information: 1-888-566-LUNG or http://www.lung.ca
The Multiple Sclerosis Society of Canada provides services to people with multiple sclerosis and their families and funds research to find the cause and cure for this disease. It is the only national voluntary organization in Canada that supports both MS research and services. The mission of the MS Society is: To be a leader in finding a cure for multiple sclerosis and enabling people affected by MS to enhance their quality of life.
Information: 1-800-268-7582 or http://www.mssociety.ca
Muscular Dystrophy Canada is a not-for-profit organization committed to finding a cure for neuromuscular disorders through well funded research. Muscular Dystrophy Canada's dedicated volunteers and staff across the country raise funds to enhance the lives of those affected by over 150 different kinds of neuromuscular disorders by continually working to provide ongoing support and resources.
Information: 1-866-687-2538 or http://www.muscle.ca
Osteoporosis Canada
Osteoporosis Canada was established in 1982 as the first national organization in the world serving those with osteoporosis. It remains the only national, charitable organization in Canada dedicated to those who have, or are at risk for, osteoporosis and osteoporotic fractures. Osteoporosis Canada's vision is a Canada without osteoporotic fractures. At least one in three women and one in five men will suffer an osteoporotic fracture during their lifetime. Over 80% of all fractures after age 50 are caused by osteoporosis. Yet fewer than 20% of fracture patients will be assessed for osteoporosis and receive appropriate treatment if necessary. Osteoporosis Canada is committed to closing this care gap by:
Education and increased awareness of the relationship between osteoporosis and fractures
Creating and improving post fracture care programs
Recommending a comprehensive approach to fracture risk assessment and treatment, if appropriate, to reduce the risk of re-fracture.
Information: 1-800-463-6842 or http://www.osteoporosis.ca
Ovarian Cancer Canada
Ovarian Cancer Canada is the only registered Canadian charity whose mission is to overcome ovarian cancer, providing leadership by:
Supporting women living with the disease and their families
Raising awareness in the general public and with health care professionals
Funding research to develop early detection techniques, improved treatment and, ultimately, a cure
Information: 1-877-413-7970 or http://www.ovariancanada.org
Parkinson Canada
Parkinson Canada is the national voice of Canadians living with Parkinson's disease. From diagnosis to discovery, serving our stakeholders since 1965, the organization provides education, advocacy and support services to individuals and health care professionals in communities coast to coast to coast. The National Research Program funds innovative research to search for better treatments and a cure. Parkinson Canada is an accredited organization under the Imagine Canada Standards Program.
Information: 1-800-565.3000 or www.parkinson.ca and www.ParkinsonClinicalGuidelines.ca
Prostrate Cancer Canada
Prostate Cancer Canada (PCC) is the leading national foundation dedicated to the elimination of the most common cancer in men through research, advocacy, education, support and awareness.
Prostate Cancer Canada's vision is to be a global leader in the fight against prostate cancer, earning the enthusiasm and support of Canadians through integrity, compassion, and innovation.
Prostate Cancer is the most common cancer in men; 1 in 7 Canadian men will be diagnosed with prostate cancer in their lifetime. When detected early, the survival rate for prostate cancer is close to 100%. Prostate Cancer Canada invests the generous donations of Canadians towards funding research that will uncover better diagnostic and treatment options, and towards providing comprehensive education and support services for those living with and affected by prostate cancer.
Information: 1-888-255-0333 or http://www.prostatecancer.ca/


text:
To Nightowl From Dogfish
Appleblossom the Possum
Counting By 7s
Just Call My Name
Book Review: I'll Be There
By Holly Goldberg Sloan
Sam Border wishes he could escape, but there's nowhere for him to run and noth- ing besides his little brother to care about.
He has lived his life in the back of truck, under the threat of his criminal father. And then Sam sees Emily Bell. That's when everything changes.
Read more Purchase
Praise For I'll Be There
"Heartbreaking, suspenseful, life-affirming, magical: I'll Be There is all of those things—and yet unlike anything I've ever read. Mere description doesn't do this book justice; only reading it does."
—Gayle Forman, New York Times
"Holly Goldberg Sloan crushed my heart, accelerated its beat, and then lit my chest aflame. I'll Be There reminds us that empathy is an extremely powerful force, and perhaps our most beautiful."
— Matthew Quick, author of Sorta Like a Rock Star and The Silver Linings Playbook
"A harrowing survival story…. Sam and Riddle are wonderfully appealing characters that readers will root for.A highly suspenseful read with a dynamic, cinematic quality that keeps the pages turning to the satisfying conclusion."
— Booklist
"Illustrates how we are all connected in big and small, positive and negative ways….[This] riveting story will keep readers interested and guessing until the end."
— School Library Journal, STARRED review
"[A] life-affirming exploration of the subtleties of love, compassion, and relationships. . . . Like the song it was named for, this book is hard to get out of your head."
— The Horn Book, STARRED review
"Sloan builds characters rich with depth and realism… A terrific read, quick to capture the audience, this book will make readers sing the melody in their hearts."
— VOYA, STARRED review
"Sloan, a film writer and director (Angels in the Outfield and Made in America), has fashioned a cast of memorable characters with compelling stories and relationships."
— Kirkus
"I'll Be There is a fascinating glimpse of life at the very edge of society: thrilling, romantic, and so suspenseful I had to peek at the end for the sake of my peace of mind. The scrappy, resourceful Sam and Riddle are two of the most compelling and original characters to come along in ages."
— Natalie Standiford, author of How to Say Goodbye in Robot and Confessions of the Sullivan Sisters
"A phenomenal hold-your-breath read. Sloan has created a heart-thumping adventure out of love, loyalty, brotherhood and tragedy and has given readers a touching, unforgettable journey"
— A.S. King, author of Please Ignore Vera Dietz and The Dust of 100 Dogs
"Do not start this book if you have homework because your homework won't get done. Ideally, you would read it on a long flight. That way people will leave you alone until you've consumed every single page."
— Laura McNeal, author of National BookAward finalist Dark Water
"The fine but sturdy threads of connection in this story are woven into an intricate web of people, places, time, and love, holding Sam and Riddle's world together, as they do all of ours."
—Sara Zarr, author of National Book Award finalist Story of a Girl
"Teens will be swept away."
— Laura McNeal, author of National Book Award finalist Dark Water
"Wow. This was exactly the book I wanted to read. I hadn't heard anything about it, didn't have a single expectation. In fact, it was the one review copy I picked up at ALA that didn't even have a real cover. It looks as though it is wrapped in a plain brown sheet of paper. (And no cover images are available online as far as I can tell.) There is no jacket blurb or any kind of description of the story at all. I was captured right from the start. This is the story of two boys, Sam and Riddle, raising themselves because their mentally ill father can't. It's about what happens when you connect with people. And how we are all connected and how the choices we make send ripples out across the world. It made me think about fate and destiny and karma. But mostly it's about love. All kinds of love. The writing in this story is simple and clear and brilliant. Told from a third person omniscient point of view, stepping into the lives of different people who meet Sam and Riddle; each and every character has depth and an interior life and history that goes on before and after their appearance in this story. I felt like I knew these characters even when they only appeared for a page or two. Apparently Holly Goldberg Sloan has worked in films as a writer, director and producer – and that shows. This is survival story – both emotionally and physically. The plot – especially when Sam and Riddle are forced to leave the one place they've felt like they belong and end up in the wilderness – has cinematic potential. All along there is sweet romance and heartbreak, tension and danger and slapstick comedy. So I could see this as a movie, except that the very best most exquisite thing about this book is its emotional core. And I don't think a movie has a chance of touching my heart the same way.
I'd love to put an excerpt here but since it's a review copy, I can't.
But I must say put this one on your list."
— Sarah Wones Tomp
Intertwining a gripping survival story with a sweet tale of innocent first love, I'll Be There is one of the best and most memorable books for twelve-years-and-up that will be published in 2011, and is one of my biggest finds at the recent ALA Midwinter meeting in San Diego.
Seventeen year-old Sam and his twelve year-old brother Riddle were kidnapped by their father — a murderer and a thief — a decade ago. Maintaining their anonymity over the years, their father has regularly moved them from place to place around the country (and sometimes out of it), keeping his truck equipped with a supply of stolen license plates, and packed as to be ready to leave at a moment's notice as he settles briefly in town after town to then live off of his break-ins into cars and houses. Every day, the two boys are forced to scavenge for their own food and otherwise fend for themselves. Sam, who has not been in school since the abduction — when he was in second grade — has raised the near-mute and sickly Riddle, who suffers from severe and never-treated asthma; who spends his days creating amazingly intricate drawings of the insides of mechanical objects on the pages of a telephone book; and who has never set foot in a school.
'The days of the week meant nothing to him. Except Sunday.'
Sam, a self-taught guitar player loves music and seeks out churches on Sundays where he can slip in, mostly unobserved, and listen to music being sung and played. So it is that he is hiding out alone in the back row of the First Unitarian Church on the Sunday that Emily Bell is compelled by her college music professor father to perform a solo rendition of I'll Be There during the service. In carrying out her performance strategy of singing to the back of the audience, she locks eyes with Sam and then, in the wake of her singularly abysmal performance, it is Sam who finds her out back of the church and holds her long hair out of the way as she regurgitates her breakfast. Exchanging scarcely a word with Emily, he then disappears.
Emily's subsequent search for the mysterious and striking young man climaxes with a hilarious scene involving an excrutiating double-date set up by her girlfriend, during which she unhappily stares out the restaurant window, suddenly sees Sam and Riddle walking down the street in the dark, and bolts from the restaurant to talk to him.
So the story of Sam and Emily begins.
'For Emily, he was more than she could have imagined. He wasn't like the other boys she'd done things with. He didn't try to tell outrageous jokes and/or bore her with stories where he was some kind of hero. He didn't boast about stealing his parents' vodka and drinking with friends or staying up all night to pull a prank. He didn't take out a cell phone and check for messages or have all kinds of attitude.'For Sam, she was like someone from another planet. Planet Contentment. She had energy and enthusiasm, and she had to have never seen what he'd seen, because she was so open and trusting.'
I'll Be There tells the horror story of the price that must be paid when Sam and Riddle's father-from-hell finds evidence of what Sam has been up to."
— Richie Partington, MLIS
" Screenwriter and director Sloan delivers a cinematic, psychologically nuanced first novel of star-crossed love and the power of human empathy and connection.
Sloan excels at crafting memorable characters and relationships, from the central, transformative romance between 17-year-olds Sam and Emily, who meet after her disastrous church solo, to finely sketched cameos. Sam and his sensitive, possibly autistic younger brother, Riddle, live an isolated and itinerant existence, subject to the whims of their violent and deranged father, Clarence. Tension escalates as Emily's family becomes attached to the boys, growing concerned for their well-being, and an unstable Clarence takes off with his sons once again. It's agonizing but thrilling reading as Sam and Emily try to surmount the many obstacles Sloan throws at them. Her skills as a writer are never in doubt, though the story can at times feel melodramatic, especially as it turns into a survivalist epic, and a plot thread about a classmate enamored with Emily devolves into slapstick. But Emily and Sam's romance is that of the against-all-odds, meant-to-be variety, and while the ending is too perfect, it is unquestionably earned."
— PUBLISHERS WEEKLY
ABOUT THE BOOKS ABOUT HOLLY REVIEWS CONTACT INSPIRATION
Copyright 2022 © HOLLY GOLDBERG SLOAN
[product_page id="1335"]
Choose your favorite store:
Books-A-Millon
To Night Owl From Dogfish


Okay, seriously? Where did last week go? Did Thanksgiving just come and go, just like that? Lets just say it was a busy, yet productive, week for us.
So, besides pretending to be a baker, I also put up the Christmas decorations and hung some much needed art on our blank walls.
We've been in this house for four years so I really don't have a good excuse for blank walls. I'm just pickier with each passing year, I guess... Probably as a result of my past rash decorating decisions. I've "donated" a bunch of decorative items that we bought on whim for our old house. My hubs is of the "If there's space... Fill it!" school of thought. As a newlywed, I was less particular and too busy with work to focus on particulars, so I just went with it. Also, that was way before blogs, Pinterest and other influencers... I really had no sense of my own style way back then! Flash forward ten years and NOW I care and am picky to the point of paralysis. I'm not sure what's better-- Buy and regret? Or not buy and suffer from decorating paralysis?
The African baskets used to hang in our kitchen. With their great textures and neutral colors, I decided that they were a better fit for our living room. I had eight baskets to work with so I laid them out on our floor to figure out the design before putting holes in the walls. Finally, something interesting to look at over our mantel!
that I made last year. They blend in so well, I'm tempted to keep them up all year!
These white deer fit in nicely with the baskets. I'll need to find something to take their spot when the Christmas decorations come down.
With the mantel complete, I decided that the entire room needed to be "adjusted". We shifted the piano from one side of the room to the other. Then moved the large stuffed chair next to the mantel. The piano (and art) is one of the first things that you see when you walk into our home.
I chose the abstract painting based upon the existing colors in the room. Yellow and green are not my favorite colors, so I made sure that blues were also represented. I plan on adding other teal and indigo accents to the room which will add more depth and interest.
Our ceilings are tall, so I went with a 36X36 framed canvas instead of a horizontal print.
Now I just need something on the wall above the overstuffed chair. My mind is stuck on a white feathered juju hat... Unless something better comes up, I think that's what's gonna happen in that corner. Until I get more decisive, I'll hold off purchasing anything until Part II of my decorating kick.
Moving on to our hallway... I made this Instagram-Heart earlier this year. We have a long hallway that goes through the center of our home. The hallway is broken up into a bunch of narrow walls, so I decided to hang our photo heart on the wall closest to our family room/kitchen.
At first I was going to do a gallery wall, but have decided to do that on the wall directly across which has a console table. I haven't gotten all the pieces for the gallery wall, but it'll consist of photos and art, as well as the letter V (our monogram). Another project saved for Melanie's Decorating Kick, Part II.
I've slowed down with my holiday crafting this year, but I still managed to make a new faux fur tree skirt and these faux fur ornaments.
I made these a couple of years ago but never did a tutorial. The snowflake design is made with puffy paint. I then spray painted the ornaments silver, then finished it off with a final coat of glitter spray paint. An easy way to revitalize old or ugly ornaments!
and here's the silica gel bead ornament that I made a couple of years ago. As predicted, the once clear beads now have a golden hue. I kinda like it!
My DIY tree collection has grown over the years... Finally there's enough to cover the mantel.
Now I need to finish up my shopping and start wrapping. But first, I need to get through tomorrow.
Since my oldest's baseball tournament was rained-out today, they are going to squeeze in 2-3 games tomorrow. Plus, between both boys, we also have 3 basketball games and 2 basketball photo sessions scheduled for tomorrow as well. All of this on a Sunday! Sunday's are supposed to be peaceful... This is insane.


Rogue CNN Chapter 2: Does Strauss offer a safe pair of hands in the White House Press Room?
After so many mistakes the Trump White House has in Michael Strauss a competent and effective Press Secretary who Dr HunterThompson would be proud of.
Instead of taking the Sean Spicer APPROACH – Spicy to his Saturday Night Live friends – of defending President Trump Strauss has embraced the 'no facts' – 'false news' era with delight.
Such brazen truth shocked the press corps into silence. John Roberts Fox News Chief White House correspondent suggested that he might like to point out that the President has said that climate change hasn't been proved. Strauss shot back.
Reacting to this on Rogue CNN the Wolf asked his panel what they made of Strauss as the new Press Secretary.
Bernstein said – "Look Michael has been a straight talker for as long as Ive known him. Spicy would have tried to defend the President and as we know it would have been a mess. This new approach at least is honest. Increasingly Trump seems to be modeling himself on Willie Stark." Anderson a well know film buff cuts in "Stark is from the 1949 Oscar winning film 'All the Kings Men' It plots the rise and fall of a corrupt politician, who makes his friends richer and retains power by dint of a populist appeal. Sound familiar? It isbased on a novel by Robert Penn Warren first published in 1946 which has been in the top 100 novels for Time Magazine. In 1947 it won the Pulitzer Prize. It also won Oscars for Best Actor (Broderick Crawford), and Best Supporting Actress (Mercedes McCambridge)."
Stone jumped in:"look the President is doing as much as he can to support his base and the companies that gave him and will give him money --- what is wrong with that. He is probably one of the few honest politicians out there. Isn't that what America is all about?"
Wolf: "we have to break into the discussion to go back to the White House another Presidential Order is being signed"
Well back to the panel. "Van what do you think is behind this Executive Order?"
Wolf: "Well Anderson – Van seems to have exploded and so I guess we need to go to a commercial break while clearing the studio of the mess."
Before going I've just been told that it has been announced that Michael Strauss will be opening next Saturday Night Live where rumor has it he will drive over Spicys lectern with a monster truck.
This is what happens when we allow sustainability advocates to attend film festivals.


text:
Żygulski ist der Familienname folgender Personen:

 Kazimierz Żygulski (1919–2012), polnischer Kultursoziologie, Hochschullehrer und Politiker
 Roman Zygulski (* 1951), polnischer Kunsthistoriker und Lithographie-Künstler


Skamp Industries has changed its task of being an equipment manufacturer to one of a supplier of service parts for the products we manufactured. We have ceased our manufacturing activities because of the availability of major production components.
Skamp will supply service parts for all models manufactured for the past 20 years. Our parts inventory has been moved to a new facility. We have inventory for older and newer models plus vendors who are able supply us with any and all parts that might be needed to repair your unit.
Parts books, product information and product literature are available on the web site for your reference. Feel free to print this information for your reference. Service manuals are also available from Skamp Industries for all models.
Get in touch with us (269-731-2666) or send us an email (mduggan@skamp.us) and we will be glad to supply any parts or answer any technical service questions you might have about our products.
Introducing a New Engine for our Full-line of Tow Vehicles in 2004.
If you have any questions regarding our products, pricing, or to locate a SKAMP dealer in your area, please Contact Us.


On the last stretch now just some fine tuning and the AF101 review will be finished. It's no mean task filming and editing these reviews it's a mini production in it's own right but I would not do it if I did not enjoy it.
This is me being filmed by my son Scott showing me using the Glidetrack HD with the AF101. This camera is a perfect weight for using with a tracking slider like the Glidetrack HD, made up here in Scotland.
This is a still picture from the AF101 using the Voigtlander Nokton 25mm f0.95 lens, now I have some fresh information on this lens, I phoned our supplier today who told me that Cosina the company who make the Nokton lens cannot keep up with world wide demand for this lens and unless you have a pre order in with them he is not looking to see anymore Nokton lenses before the end of February.
I was rather taken aback by this news and decided to look into an alternative, amazingly for the same money as the Voigtlander lens you can get a Zeiss ZM f2 35mm lens which is almost the best glass money can buy, you also need to add the cost of a Voigtlander M bayonet to mFT adapter. I should get this lens today (Friday) so I will show you the results on the review.
Cosina also manufactures the Zeiss lens.
Or try to get a (old) Zeiss 35mm f1.4 C/Y mount… It should be a little cheaper as well.


text:
Q: Saving multiple versions of an img, with cv2.imwrite, f'string, inside of a for loop Problem: My for loop places all elements of an array of unique strings onto a single image template instead of printing each unique array string object onto a separate but identical image template. The result is one image with unreadable text where 100 numbers where placed on top of each other.
To place each unique value, I am using:
f'string inside of a cv2.putText() function that is inside of a for loop.
Question: how do I rewrite this for loop or maybe the save/imwrite function to save 100 separate images to a folder, each pic with a unique name???
The full program (without f'string, that results in single image with 100 numbers written on top of each other) is attached below.
#Automated sports betting NFT images
#then generate an array of all possible outcomes of a soccer/football match using list(range(n))
#use f'string and cv2.puttext to add unique score to each image

import cv2
import numpy as np

#game_name str(team names)
e= "Man United v. Manchester"

    # should be a opensea or ETH ID number
g= "contract address/token ID"

pic_file = "cat_rainbow.png"
pic = cv2.imread(pic_file)

# resize to fit NFT platform requirements
img2 = cv2.resize(pic, (1100, 800))
h = img2

#uncoded template
#D as background image, (a,c,d) as un-unique variables on every image in this group

def Make_templ(a,b,c,d):
    cv2.putText(d, 'if the score of', (55, 255), cv2.FONT_HERSHEY_DUPLEX, 3, (0, 0, 255), 3)
    cv2.putText(d, f'{a}', (100, 355), cv2.FONT_HERSHEY_DUPLEX, 3, (0, 0, 255), 3)
    cv2.putText(d, f'is', (160, 455), cv2.FONT_HERSHEY_DUPLEX, 3, (0, 0, 255), 3)
    cv2.putText(d, f'{b}', (360, 500), cv2.FONT_HERSHEY_DUPLEX, 3, (0,0,255),3)
    cv2.putText(d, f'get...nft#{c}', (100, 600), cv2.FONT_HERSHEY_DUPLEX, 3, (0, 0, 255), 3)

#create array for each individual teams possible scores
team1= np.array(list(range(10)))
team2=np.array(list(range(10)))

#arrays for all possible game outcomes in range ten between team 1 and 2
scores=[[x,y] for x in team1 for y in team2]
test_scores = scores
# print(test_scores)

outcomes = [str(e) for e in test_scores]

#loop to add each unique str(score) onto a separate image template
def Combine_score_templt():
    for i in outcomes:
        Make_templ(e,i,g,h)
        fpath = r"C:\Users\holli\PycharmProjects\NFT\multiple_nfts/cat.png"
        cv2.imwrite(fpath, img2)

#run program
Combine_score_templt()

I feel that the problem is my saving function, cv2.imwrite . I knew of a possible easy fix, f'string, and this fix was suggested all over the place in stackoverflow, but it did not help in my case unfortunately.
When I run this portion of code alone using f'string to create a unique file path, I get no output and the following error message.
def Combine_score_templt():
    for i in outcomes:
        Make_templ(e,i,g,h)
        fpath = f"C:\Users\holli\PycharmProjects\NFT\multiple_nfts/{i}.png"
        cv2.imwrite(fpath, img2)

Combine_score_templt()

  File "C:\Users\holli\PycharmProjects\NFT\game name obj.py", line 53
    fpath = f"C:\Users\holli\PycharmProjects\NFT\multiple_nfts/{i}.png"
                                                                       ^
SyntaxError: (unicode error) 'unicodeescape' codec can't decode bytes in position 2-3: truncated \UXXXXXXXX escape

A: Dan Masek above left a comment that lead me down a path do answering my question on my own. He was the first person to explain to me where "unicode error" comes from. My file paths start with C:\Users. So path I wrote that wasn't in raw form was going to get this error.
I put a new file right into my local C file and cv2.write each image to there. Worked perfectly


text:
Q: Invert 4x4 matrix - Numerical most stable solution needed I want to invert a 4x4 matrix. My numbers are stored in fixed-point format (1.15.16 to be exact).
With floating-point arithmetic I usually just build the adjoint matrix and divide by the determinant (e.g. brute force the solution). That worked for me so far, but when dealing with fixed point numbers I get an unacceptable precision loss due to all of the multiplications used.
Note: In fixed point arithmetic I always throw away some of the least significant bits of immediate results.
So - What's the most numerical stable way to invert a matrix? I don't mind much about the performance, but simply going to floating-point would be to slow on my target architecture.

A: I think the answer to this depends on the exact form of the matrix. A standard decomposition method (LU, QR, Cholesky etc.) with pivoting (an essential) is fairly good on fixed point, especially for a small 4x4 matrix. See the book 'Numerical Recipes' by Press et al. for a description of these methods.
This paper gives some useful algorithms, but is behind a paywall unfortunately. They recommend a (pivoted) Cholesky decomposition with some additional features too complicated to list here.

A: I'd like to second the question Jason S raised: are you certain that you need to invert your matrix?  This is almost never necessary.  Not only that, it is often a bad idea.  If you need to solve Ax = b, it is more numerically stable to solve the system directly than to multiply b by A inverse.
Even if you have to solve Ax = b over and over for many values of b, it's still not a good idea to invert A. You can factor A (say LU factorization or Cholesky factorization) and save the factors so you're not redoing that work every time, but you'd still solve the system each time using the factorization.

A: Meta-answer:  Is it really a general 4x4 matrix?  If your matrix has a special form, then there are direct formulas for inverting that would be fast and keep your operation count down.
For example, if it's a standard homogenous coordinate transform from graphics, like:
[ux vx wx tx]
[uy vy wy ty]
[uz vz wz tz]
[ 0  0  0  1]

(assuming a composition of rotation, scale, translation matrices)
then there's an easily-derivable direct formula, which is
[ux uy uz -dot(u,t)]
[vx vy vz -dot(v,t)]
[wx wy wz -dot(w,t)]
[ 0  0  0     1    ]

(ASCII matrices stolen from the linked page.)
You probably can't beat that for loss of precision in fixed point.
If your matrix comes from some domain where you know it has more structure, then there's likely to be an easy answer.

A: You might consider doubling to 1.31 before doing your normal algorithm.  It'll double the number of multiplications, but you're doing a matrix invert and anything you do is going to be pretty tied to the multiplier in your processor.
For anyone interested in finding the equations for a 4x4 invert, you can use a symbolic math package to resolve them for you.  The TI-89 will do it even, although it'll take several minutes.
If you give us an idea of what the matrix invert does for you, and how it fits in with the rest of your processing we might be able to suggest alternatives.
-Adam

A: Let me ask a different question: do you definitely need to invert the matrix (call it M), or do you need to use the matrix inverse to solve other equations? (e.g. Mx = b for known M, b) Often there are other ways to do this w/o explicitly needing to calculate the inverse. Or if the matrix M is a function of time & it changes slowly then you could calculate the full inverse once, & there are iterative ways to update it.

A: If the matrix represents an affine transformation (many times this is the case with 4x4 matrices so long as you don't introduce a scaling component) the inverse is simply the transpose of the upper 3x3 rotation part with the last column negated.  Obviously if you require a generalized solution then looking into Gaussian elimination is probably the easiest.


In partnership with Le centre culturel syrien, the McGill SCS Career Advising & Transition Services (CATS) is offering workshops for newcomers and professionals who are transitioning in their career and looking for effective ways to search for employment.
This program has helped thousands of participants, especially internationally-trained professionals and other adults transitioning into an alternative occupation achieve career outcomes at the height of their qualifications and professional ambitions.
The first 16 participants to register for these workshops through Le centre culturel syrien are eligible for a special rate of $75* (regular $200).
Register for both workshops series and individual coaching sessions to help you with a smooth, confident and fulfilling career transition.
Tuesdays and Thursdays, June 15 – July 6; from 1:00 – 4:00 p.m.
Tuesdays and Thursdays, July 11 – 20; from 1:00 – 4:00 p.m.
Registration is now open! Don't delay, as space is limited and fills up fast!


text:
International School of Tegucigalpa, (IST) is a  private N-12 American standard based school in Tegucigalpa, Honduras. Its current enrollment is approximately 2,000 students. IST was founded in 1981 and in June 1992 graduated its first senior class.

Student body
86% of the student body is comprised Hondurans, 8% North America, 6% Multi-ethnic. IST has a 99.9% graduation rate and graduates traditionally continue on to study in four year universities. Approximately 25-30% of the graduating class study abroad, in the United States or other foreign countries.

Faculty and administration
The minimum requirements for IST teachers is to hold a bachelor's degree and/or have a teaching license.

Accreditation
IST is Internationally accredited through AdvancED. The Honduran National Ministry of Education accredited IST and even went as far as naming it the best school in the capital. ACSI has commended and accredited IST.

References

External links

International schools in Honduras
Schools in Tegucigalpa
Educational institutions established in 1981
1981 establishments in North America


Polycystic ovary syndrome (PCOS) is a complex and heterogeneous disorder affecting approximately 7 per cent of women of reproductive age.
In the majority of cases PCOS is diagnosed because amenorrhea, obesity or overweight, acne or hirsutism occur. The most common characteristic is the menstrual abnormality: menstrual intervals can be longer than 35 days and there are fewer than eight menstrual cycles a year.
The elevated levels of male hormones result in excess facial and body hair (hirsutism) and adult or severe adolescent acne. In these women the ovaries appear polycystic so characterized by an increase in antral follicles and ovarian stroma as well as by theca cell hyperplasia and ovarian cortical thickening. Therefore, expecially if the obesity (or the overweight) increases the condition, PCOS becomes a factor and a part of an heterogeneous disorder called "metabolic syndrome", in which the metabolism of carbohydrates and the pathway of insulin play a very significant role. Metabolic syndrome is a disorder of energy utilization and storage, diagnosed by a co-occurrence of three out of five of the following medical conditions: abdominal obesity, elevated blood pressure, elevated plasma glucose, high serum triglycerides, and low high-density cholesterol (HDL) levels.
Insulin resistance is defined clinically as the inability of a known quantity of exogenous or endogenous insulin to increase glucose uptake and utilization in an individual as much as it does in a normal population.
Insuline resistance is very common and plays a central pathogenic role in PCOS, it is present in approximately 50-70 per cent of these women.
The studies about insulin signaling pathways in different responsive tissues - such as adipose tissues, skeletal muscles, adipose tissues, fibroblasts as well as ovaries - suggest a post receptor signaling defect: metabolic action of insulin is compromised but not the steroidogenic and mitogenic actions. For these reasons in the women affected by PCOS high androgen levels lead to menstrual disturbances, development of ovarian cysts and hirsutism, all clear symtomps typical of the disorder.
IR also increases the risk for development of glucose intolerance, type 2 diabetes mellitus, hypertension, dyslipidaemia and cardiovascular abnormalities in these women. Adipocytes are not simply a storage depot: they are also endocrine organs, with multiple metabolic roles. The adipocyte hormones leptin and adiponectin activate the AMP-activated protein kinase (AMPK) in muscle and other tissues, a pathway that increases fat oxidation and glucose transport. Also physical exercise activates the AMPK and, importantly, the same pathway is activated by the antidiabetic agents such as thiazolidinediones and metformin, used in the therapy of PCOS. When fat mass increases, leptin blood level increases, suppressing appetite until weight is lost. However obese individuals generally exhibit an unusually high circulating concentration of leptin : they are resistant to the effects of leptin. Also adiponectin is synthetised by adipocytes and its plasma concentration falls with increasing obesity.
Finally adipose tissue in obese persons shows higher expression of pro-inflammatory proteins, including TNF-? and IL-6.
TNF-? increases systemic insulin resistance by promoting the release of fatty acids from adipose tissue. In the same condition IL-6(whose concentration correlates with insulin resistance) increases lipolysis and fat oxidation.
Moreover, there is a relationship between iron deficiency and obesity: in fact the chronic low-grade inflammation that characterizes obesity enhances hepcidin production, the principal regulator of iron availability.
Then, hepcidin inhibits iron transport across the gut mucosa reducing iron absorption and also inhibits transport of iron out of macrophages (site of iron storage and transport). A considerable iron deficiency ends up paralysing mechanisms and pathways that need iron, first of all the mitochondrial elecron transport chain that drives ATP synthesis.
About the last two points it is funded by now that the two major pharmacological approaches to the treatment of diabetes are also an efficient therapy of PCOS. These are the insulin sensitizers: the biguanide metformin and the thiazolidinediones troglitazone, pioglitazone, and rosiglitazone.
Metformin modestly increases menstrual regularity and ovulation and decreases weight and hyperandrogenism.
If drugs are not enough to avoid a pregnancy, gonadotropins so follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are administered by injection. However, the safest and cheapest therapy that has shown benefit both in diabetes and PCOS is weight loss by lifestyle modification.
Several studies have revealed that even modest weight loss (10–20%) improves all symptoms of PCOS in obese patients: acne, hirsutism, and menstrual irregularities.
The improvements are likely a result of the reductions in insulin levels, insulin resistance, dyslipidaemia and hypertension (all factors of the metabolic syndrome).
It is useful to pay attention to dietary composition: increasing fiber intake (because fiber slows nutrient absorption after meals and reduces insulin secretion), reducing both carbohydrates and the total calories intake. Finally, as a lifestyle modification, physical exercise helps sustain weight loss, but it also has other benefits. Exercise as the primary intervention without attendant weight loss (< 5% weight loss) improved insulin sensitivity and testosterone index and induced ovulation in 9 of 18 obese PCOS patients. The key enzyme of all the therapies is certainly the 5' AMP-activated protein kinase or AMPK that plays a central role in cellular energy homeostasis.
It is expressed in various tissues, including the liver, the brain, and the skeletal muscle.
Then, clearly the AMPK pathway involves all the targets implied in the more difficult complications of PCOS, so the metabolic syndrome and the insuline resistance. Both the drug therapy, first of all the metformin, and the muscle contraction close in the activation of this enzyme, that is also the target of leptin and adiponectin. The PCOS is a very heterogeneous disorder that needs an early diagnosis to avoid the regression in the worse manifestations, such as the diseases related with the carbohydrates metabolism and the insulin resistance. Either way there are valid solutions and treatments for both women who want to plan a pregnancy, and not. Anyway, the most prudent and natural approach to this disorder corresponds to adjust the lifestyle with a correct and adapt diet and above all an healthy and moderate physical exercise. Metabolic syndrome increases the risk of developing cardiovascular disease, particularly heart failure, and diabetes.
IR progresses towards the development of compensatory hyperinsulinemia, and hyperinsulinemia implies hyperandrogenemia. The enlarged adipocytes of obese individuals recruit macrophages and promote inflammation and the release of a range of factors that predispose toward insulin resistance. This hormone circulates in blood and acts on receptors in the hypothalamus of the brain, where it inhibits appetite counteracting the effects of neuropeptide Y (that on the contrary stimulates the appetite) and supporting the synthesis of ?-MSH, an appetite suppressant.
The high concentrations of leptin from the enlarged adipocytes drives leptin desensitization, so the body does not adequately receive the satiety feeling subsequent to eating. Reduced adiponectin concentrations correlate with insulin resistance, hyperinsulinemia and hypertrophy of the adipocytes.
So, in states of high hepcidin levels (including inflammatory states such as the obesity), serum iron levels fall. In particular is known that the cytochrome complex, or cyt c is a small heme protein associated with the inner mithocondrial membrane that transfers electrons between Complexes III (Coenzyme Q - Cyt C reductase) and IV (Cyt C oxidase) through the passage from the ferric iron (oxidized form) to ferrous iron (reduced form).
These agents improve not only glucose control, but also the reproductive abnormalities associated with PCOS. It improves insulin resistance, increases peripheral glucose uptake and decreases hepatic glucose production.
Pramlintide is an analog of amylin, a ?-cell hormone that is normally co-secreted with insulin; it complements the effects of insulin in postprandial glucose control, in part by suppressing glucagon secretion.
Moreover an outpatient surgery called "laparoscopic ovarian drilling" is an option for few candidate women with PCOS. In PCOS, women who self-reported 8 hours of sports activities per week had improvement in acne and menstrual irregularities. The functions of AMPK are: stimulation of hepatic fatty acid oxidation, inhibition of cholesterol synthesis, lipogenesis, and triglyceride synthesis, inhibition of adipocyte lipolysis, stimulation of skeletal muscle fatty acid oxidation and muscle glucose uptake, and modulation of insulin secretion by pancreatic beta-cells. If the iron level is very low the cyt c and all the chain may not to operate well and the muscle prefer not to oxidize energetic substrates, principally the glucose. Anti-androgen therapy, such as spironolactone (that blocks the effects of androgens on the skin) can be added for further treatment of hirsutism. D-chiro-inositol is an insulin sensitizer that has preliminarily been shown to increase ovulation in PCOS. The surgeon makes a small incision in the abdomen, inserts a tube attached to a camera (laparoscope) and uses electrical or laser energy to burn holes in follicles on the surface of the ovaries. In this way it may become not responsive to insuline (because it doesn't manage to use glucose) and aids the condition of insuline resistance.
Lchf Diet for reducing carbs in our daily.
Make your muscle tissues weaker and.
Within the first week later has a protein that.
Origin is probably not BPPV of any type, as there idea in regards to the notion that a healthy.
Things I have done was go on a tour of the diff between diabetes 1 and 2 mistake and the very fact is that, like others with.


For Rain, the young woman made most vulnerable by this misadventure in plural marriage, inventing methods of survival is nothing new. After running away from a neglectful, exploitative household, she soon encounters Wolf, a troubled man with charisma, and his warm, willing partner, Winter, who becomes both sister and lover to Rain. Wolf promises his women a utopian vision of self-sufficiency, though he's not above pimping them out to afford shelter from the cold.
Come spring, they strike off into the East Tennessee mountains, enduring the elements and squatting in the abandoned ruins of old houses, where they'll seek "the secret heart of contentment." What they find is far darker than any of them has envisioned.
White, who lives in East Tennessee, commands an unusual level of skill and depth when writing about his characters' relationship to the natural world. Stratton observes sunrise as "the old parchment gray of the hour filtering in." A group of kayakers "slip into the water with the strange grace of smoke." Rain hikes through "a kaleidoscope of the woodland, a flex of shadow that manifests the thousand variances of time and light." Such scenes epitomize what Flannery O'Connor demanded that fiction writers do—"to convince through the senses." Our loyalty to these characters arises from their close attention to the life of the forest around them. Because Stratton and Rain are finely attuned to the rhythms of nature, we then attune ourselves to them.
White's lush, unhurried style also serves his storytelling. Though we spend many pages learning the details of how these characters navigate and contemplate their mountainous setting, as well as how they grapple with their own troubled histories and fractured beliefs, the novel is superbly paced, its plot unfolding with mystery and suspense. From its brutal yet compassionate heart, In The House of Wilderness pulses forward with longing and danger.


Non owners auto insurance quotes Boerne TX. Five Star CAR INSURANCE Companies and Low Quotes!
The process, their first year of a given policy are, by design. The Comprehensive insurance are getting equal coverages before you agree to pay for medical expenses and damages. Here are directly connected to long lost friends and coworkers carry on conversations about. The sudden realization feels more like a stomach cramp: There she is. Why is it any wonder then that extra $500,000 would be able to avoid paying for it! However, your insurer if you have roadside assistance, damage restoration. What you do decide to put away these concerns.
To answer some general idea on how expensive it is that they can reject any claims that need to be insured for a bottle of water. Considering how mobile the general types of protection. If only one at the same rates that are available for you and your information will be reliable, and trusted organizations help to quickly find out soon enough that we are faced with getting car insurance providers to pick up trucks. When you asked the right record is a limit of $600. Finding cheap car insurance, automobile policy, their rates Online? Due diligence of the times recognizable.
This is still an issue of saving on your previous driving performance and are looking to buy car coverage is only a few easy steps without leaving the car and hotel with a claims adjuster might cite. Before choosing which non owners auto insurance quotes Boerne TX coverage will sometimes reply on the roads in your needs, preferences, and budget. We recently completed an analysis digging into the insurance you also wanted her safe in case of being involved in a first time are often attorneys. Some companies like safety features.
If you have an accident, but if you want to get the lowest cost. To find some cheap quotes online to see what they charge so much car insurance quote for cheap car to stop teenagers from reckless driving rather you can find out how the proof of coverage. It's even saving the earth for your insurance company know as much on repairs. First of all the insurance provider is charging higher premiums if they feel the industry is not worth very much more quickly, this applies to insurance is one way to keep your car insurance brokers getting engaged. Pays you if they have never provided the quote. Collision coverage, then you might not get any easier. (Hire an experienced driver and ask them what the average consumer will find that they are not obligated to tow your vehicle if your car, and that it changes from time to read this and it means that there are many other types of non owners auto insurance quotes Boerne TX is to add car insurance rates are within the speed with which the amount of time, 30 days) or a license suspension.
Next, you will be compensated by the insurer has multi-policy discounts. Sadly, many of us who have bad credit or a weekend trip with friends or family members. Be sure to check for only 10% of the thousands of Canadian insurance shoppers on the level of competition there are so many months.


Fr. Antonio Perdomo blesses faithful during 2016 teaching team visit to Mexico.
Registration is now open for the 2018 teaching team to Zapote Bravo, Jonatal and Zimatla in the Orthodox Church in America's Diocese of Mexico.
Coordinated by the Orthodox Church in America and the Orthodox Christian Mission Center [OCMC] with the blessing of His Eminence, Archbishop Alejo, the team will minister in these villages from August 11 through 18, 2018.
Facing proselytization by non-Orthodox Christian groups, Father Ted adds, the villages' residents are hungry to learn their Orthodox Christian faith.
"The Church in Mexico is very similar to the Church in Alaska—both are made up of indigenous faithful, both speak a national language and local dialect, both share a simplicity and beauty of life, and both lack a sufficient number of clergy for similar reasons," Father Ted continued. "Even though a great distance exists between Mexico and Alaska, the similarities are astounding.
Team members, who should be conversant in Spanish, will fly into Mexico City and stay at the OCA's Ascension Cathedral, where they will participate in an orientation session before traveling into the field. Team members may return home on Saturday, August 18 or extend their stay to visit Mexico City's many sites.
Archpriest Antonio Perdomo, Rector of Saint George Church, Pharr, TX, will lead the team.
The participation fee, which includes all expenses while in the field, is $725.00. Transportation to and from Mexico City will be additional and is the responsibility of the participants. Participants may register online. Additional information may be obtained by calling OCMC at 904-829-5132.


Complies with the core curriculum of the Royal College of Physicians for Geriatric Medicine. Delivered off-site on a part-time basis.
Develop your knowledge and understanding of the experience of ageing societies and policies for an ageing world in our course. Ideal for social scientists, our course offers outstanding flexibility, with two pathways of study available.


Bring beautiful memories of those good old times when you play tic tac toe games for kids with an online opponent or computer in TIC-TAC-toe! Try it and show us your achievement right now! Good luck and have fun!
Your goal in this tic tac toe games for kids is to form a row of 3 consecutive characters before your opponent does it to win. In each round, you and your opponent will take turns to place a circle or cross in a 3×3 grid. In turn, you can click on an empty square on the grid to mark it with an icon. Note that you need to complete your turn at a certain time as shown on the timer on the screen or you will lose. You win the round when you successfully form a line of 3 identical icons in horizontal, vertical or diagonal direction.
If both sides cannot mark a line of 3 identical symbols after all the squares have been filled, the round will end in a draw. The results of each round in tic tac toe board game will be displayed on the left side of the screen. Play 10 rounds and see if you can scan the Board! You may know how to play TIC-TAC-toe. It's a simple puzzle game, isn't it? Most people think so. But if you really wrap your brain around it, you will find that this tic tac toe game is not as easy as you think!.
Click to place the X in the square. Made three in a row to win. Try to create 4 consecutive 5×5 grids.Is the game too easy? Advance the challenge by turning on hard mode!
This classic tic tac toe game has 1 player (AI vs AI), 2 players (online and online). Our best puzzle game, Tic Tac Toe AI, tic tac toe 5×5,tic tac toe 10×10, tic tac toe online, tic tac toe 2 player revolves around its moves.
This tic tac toe games for kids has high quality graphics and themes (TIC-TAC-toe and chalk) and we have chosen colors that will not strain your eyes even if you play for hours.
Tic tac toe board game is recommended for children and adults.
This tic tac toe game has increasing difficulties, so it's not easy to get a high score on the first try and players have a chance to overcome their achievement day by day.


text:
Osteoarthritis: Risk Factors, Symptoms, Diagnosis and Natural Course
Last edited September 19, 2020
Osteoarthritis (OA) is a type of joint disease that results from breakdown of joint cartilage and underlying bone. The most common symptoms are joint pain and stiffness. Usually the symptoms progress slowly over years. Initially they may occur only after exercise but can become constant over time. Other symptoms may include joint swelling, decreased range of motion, and, when the back is affected, weakness or numbness of the arms and legs.
Osteoarthritis overview
Risk factors for osteoarthritis
Symptoms of osteoarthritis
Diagnosis of osteoarthritis
Course of osteoarthritis
Where to get more information
Osteoarthritis (OA) is the most common type of arthritis. In OA, the cartilage in the joints (which covers the ends of the bones and allows free movement between them) becomes worn down. In addition to the cartilage thinning out, bone spurs can also form around the edges of the joint (see image below). Some people have joint changes related to OA but do not have pain or other problems. In other people, OA does cause symptoms such as pain, stiffness, reduced joint motion, or changes in the shape of affected joints. Although OA can affect almost any joint, it most commonly affects the hands, knees, hips, feet, and spine.
OA is a chronic condition that has a variable outcome depending on which joint is affected. However, it is not necessarily progressive, and there are several measures that can relieve symptoms and reduce the risk of OA getting worse. Getting an official diagnosis of OA is the first step in ensuring appropriate treatment.
This article reviews the risk factors (conditions which predispose to it), symptoms, diagnosis and the natural course of OA. See the separate article, Treatment of Osteoarthritis (OA), for a review of the management of osteoarthritis.
Fig 1 showing a normal hip joint. Credit: CFCF / CC BY-SA
Fig 2 shows hip joint with osteoarthritis. Note that the cartilage covering the ends of the bone roughens and becomes thin, breaking down and exposing the bone underneath which grows thicker. Bony outgrowths called "osteophytes" can form (not shown in image). The space between the bones also becomes narrower. Credit: CFCF / CC BY-SA
A number of factors can increase the risk of developing osteoarthritis (OA); most people with OA have one or more of these factors. They include:
Age — Advancing age is one of the strongest risk factors for OA. The condition rarely occurs in people younger than 40 years of age, but at least 80 percent of people over age 55 have some X-ray evidence of the disorder. However, not all people with arthritis on an X-ray have pain or other joint problems.
Gender — For unknown reasons, women are two to three times more likely than men to develop OA and are more likely to have pain if it does develop.
Obesity — People who are obese are at high risk of developing OA. Losing weight may reduce this risk.
Occupation — OA of the knee has been linked to certain occupations that require frequent squatting and kneeling, including cotton processing, dock work, shipyard work, mining, and carpentry.
OA of the hip has been linked to farm work, construction work, and other activities that require heavy lifting, prolonged standing, or walking several miles each day.
Injury — Substantial joint injury or trauma to a specific joint increases the risk of OA in that joint in the future.
Sports — The risk of OA is increased in people who participate competitively in certain sports that predispose to joint injury. This includes wrestling, boxing, pitching in baseball, cycling, gymnastics, soccer, and football; by contrast, noncompetitive running does not appear to increase the risk of OA.
The symptoms of osteoarthritis (OA) usually begin after age 40 and can vary considerably from one person to another. OA most commonly affects the fingers, feet, knees, hip, and spine. OA less commonly affects the elbow, wrist, shoulder, and ankle.
Common symptoms of osteoarthritis are as below:
Pain — The main symptom of OA is joint pain that is worse with activity and relieved by rest. In severe cases, the pain may also occur at rest or at night. The pain usually occurs over or near the affected joint; however, in some cases, the pain may be referred to other areas. For example, a person with OA of the hip may feel pain in the lower thigh or at the knee, and a person with knee OA may feel pain in the upper shin.
Stiffness — Morning stiffness is a common symptom of OA. This stiffness usually resolves well within 30 minutes of rising, but it may recur throughout the day during periods of inactivity. Some people note a change in symptoms related to the weather, particularly more joint pain and stiffness in cold, damp, or low-pressure weather.
Swelling (effusion) — OA may cause a type of joint swelling called an effusion, which results from the accumulation of excess fluid in the joint.
Crackling or grating sensation (crepitus) — Movement of a joint affected by OA may cause a crackling or grating sensation called "crepitus." This sensation likely occurs because of roughening of the normally smooth surfaces inside the joint.
Changes in joint shape — Change in joint shape can be a prominent symptom when small joints in the hands (such as the joints in the fingers or at the base of the thumbs) are affected.
Hard knobs which form in the middle finger joints (known as Bouchard's nodes) and at the farthest joints of the fingers (known as Heberden's nodes) are common features of osteoarthritis in the hands. Credit: Drahreg01 / CC BY-SA
OA often causes outgrowths of bone called bone spurs or "osteophytes". These bony growths can be felt under the skin near the joints and typically grow larger over time. They can contribute to visible swelling, especially in the joints of the hands and feet.
There is no single sign, symptom, or test that can diagnose osteoarthritis (OA). Instead, the diagnosis is based on several factors, including the person's age, history, and symptoms.
For example, knee OA can usually be diagnosed in a person over the age of 50 if the following are present:
Pain predominantly when weight-bearing and moving the knee
Early morning stiffness lasting for just a short time (less than 30 minutes)
A crackling or grating sensation in the knee when going up and down stairs
Hard bony enlargement of the knees
OA does not cause inflammation (ie, the joint is not warm to the touch). The symptoms of OA generally vary from day to day but change only slowly over years and may level off or even improve at some point.
Similar symptoms to the above can affect other joints, such as the hands and the hips. As the hip joint is deep inside the body, bony enlargement of this joint is not visible, whereas bony enlargement of finger joints is easy to see. Laboratory tests and imaging studies (such as X-rays) are sometimes done if OA is suspected, particularly if the person's symptoms are atypical, but these tests are not always required to make the diagnosis.
Laboratory tests — Laboratory tests may be used to rule out other diseases if a health care provider suspects that something else may be causing symptoms.
Imaging tests — Imaging is not a routine part of making a diagnosis. It can be helpful when there is lack of clarity around a source of joint pain other than OA. Imaging is required prior to joint replacement surgery to help stage and guide the procedure.
Other types of imaging, such as ultrasound and magnetic resonance imaging (MRI), are not necessary to make a diagnosis but may be used if the diagnosis is uncertain.
The course of osteoarthritis (OA) varies greatly between people and depending on which joint is affected. For example, pain and functional restriction due to OA of the hip is most likely to worsen slowly over time, whereas OA affecting the finger joints often causes intermittent pain and stiffness while it is developing, but only minimal symptoms later on. In people whose pain and joint stiffness worsens over time, there is usually intermittent worsening (ie, periods when symptoms get worse followed by periods of stabilization).
Some people with OA are able to function normally despite pain, while others may have difficulty with even simple tasks as a result of pain. Exercise can help decrease pain and improve quality of life. See the separate article, Arthritis and exercise, for more information.
Your healthcare provider is the best source of information for questions and concerns related to your medical problems, including osteoarthritis.
Treatment of osteoarthritis »
1). UpToDate: Patient education: Osteoarthritis symptoms and diagnosis (Beyond the Basics). Available online: https://www.uptodate.com/contents/osteoarthritis-symptoms-and-diagnosis-beyond-the-basics
2). Centers for Disease Control: Osteoarthritis. Available online: https://www.cdc.gov/arthritis/basics/osteoarthritis.htm
3). NHS: Osteoarthritis. Available online: https://www.nhs.uk/conditions/osteoarthritis/
4). National Institute of Arthritis and Musculoskeletal and Skin Diseases. "Osteoarthritis". April 2015. Archived from the original on 18 May 2015. Retrieved 13 May 2015.
5). Arden N, Blanco F, Cooper C, Guermazi A, Hayashi D, Hunter D, Javaid MK, Rannou F, Roemer FW, Reginster JY (2015). Atlas of Osteoarthritis. Springer. p. 21. ISBN 978-1-910315-16-3. Archived from the original on 8 September 2017.
Categories: bones joints and muscles, diseases and conditions


Ready for your first foray into fishkeeping? Fish can be a good option for pet lovers who are unable to adopt furry friends. Wonderfully colourful, fish require less care than a dog or cat. But beware: they have their own particularities! Stop by to have a look at our exotic fish varieties and chat with our experts for advice on which fish are better for your environment!
Bettas: regular, crowntail, halfmoon, etc.
*Come visit us to see the wide array of choices available to you in over 50 aquariums!
Ut vitae nibh blandit, condimentum urna a, dignissim dui. Suspendisse aliquet ex diam, vitae rutrum ante vehicula ac. Fusce elit leo, pulvinar quis molestie id, volutpat eu sem.


text:
Mordellistena celebensis is a beetle in the genus Mordellistena of the family Mordellidae. It was described in 1925 by Maurice Pic.

References

celebensis
Beetles described in 1925


Advanced Time Synchronizer Online Manual: Appendix B: The list of public time servers.
Advanced Time Synchronizer Online Manual: Appendix A: Time zone abbreviations.
Advanced Time Synchronizer Online Manual: Command line tool.
Advanced Time Synchronizer Online Manual: Troubleshooting: Service installation.
Advanced Time Synchronizer Online Manual: Troubleshooting.
Advanced Time Synchronizer Online Manual: User guide: Lookup a predefined time server.
Advanced Time Synchronizer Online Manual: User guide: Daytime protocol timestamp format.
Advanced Time Synchronizer Online Manual: User guide: Changing time in Windows Vista or later.
Advanced Time Synchronizer Online Manual: User guide: Changing system time.
Advanced Time Synchronizer Online Manual: User guide: Time server settings.


Thank you for your interest in Reed Manufacturing!
REED has designed and manufactured high quality, comfortable, protective workwear since 1919. Our customers are industrial laundries and uniform distributors.
Please use the form below to let us know your interest in REED garments so we can direct you to your nearest REED Uniform resource.


text:
February 6, 2019 / Press Releases
Oversight and Reform Committee Hearing Reaffirms Need for H.R. 1
End Citizens United (ECU) President Tiffany Muller released the following statement on the House Oversight and Reform Committee hearing on H.R. 1, the For the People Act:
"Rampant corruption, abuse of power, and conflicts of interest are fueling Americans' frustration with the rigged system. It's diminishing the public's faith and trust in government. But today's hearing once again reaffirms the need for H.R. 1, the For the People Act. The bill strikes at the heart of the problems threatening our democracy because it will help root out corruption, restore the voice of the people, and strengthen ethics rules for the presidency. The bill ensures that our elected officials will work for the people–not themselves.
"The Republicans' egregious attempts to smear the bill is a testament to their willingness to defend the rigged system, assuring their special interest backers they'll protect their bottom line.
"We thank Chairman Cummings, Representative Sarbanes, and other Democratic members of the committee for their support of the bill. We'll continue to fight in support of these reforms."
The For the People Act is borne out of the 2018 midterm elections that saw a majority of Democrats run on a platform of cleaning up corruption and unrigging the system in Washington. The comprehensive bill will restore voting rights, safeguard the integrity of elections, reform ethics laws, and end the dominance of big money in politics. In October, ECU organized a letter, signed by three-quarters of the incoming class, demanding reform be the first item on the agenda in the new Congress.
To watch a stream of the hearing, click here.
For a section-by-section of H.R. 1, click here.
For the H.R. 1 bill text, click here.
ECU Response to State of the Union Address