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Blu-ray Review "Marvel's Captain America: The Winter Soldier"
September 10, 2014 by Mike Gencarelli Leave a Comment
Actors: Chris Evans, Scarlett Johansson, Sebastian Stan, Anthony Mackie, Cobie Smulders
Directors: Anthony Russo, Joe Russo
Rated: PG-13 (Parental Guidance Suggested)
Studio: Walt Disney Studios Home Entertainment
Film: 4 out of 5 stars
Blu-ray: 5 out of 5 stars
Extras: 3 out of 5 stars
Is there simply any stopping Marvel at this point? "Marvel's Captain America: The Winter Soldier" is the latest film in the Cinematic Universe that Marvel is building, all so well! The film is really well done. It follows the events of "Captain America: The First Avenger" and of course "The Avengers". There are tons of Easter eggs hidden throughout the film. It is well-paced and takes a very important stand in Marvel Cinematic Universe. Chris Evans is great as always. Scarlett Johansson gets some more screen time and a chance to chat as Black Widow…but when is that solo movie going to be announced. I have to say I think that Anthony Mackie steals the show as Falcon for sure. I wanted more of him. Sebastian Stan, played the Winter Soldier, signed a nine picture deal with Marvel/Disney, so are going to be seeing a lot more of him. Can't wait to see how this all comes together now in "The Avengers 2".
Official Premise: From the Studio that brought you the greatest Super Hero movie of all time, "Marvel's The Avengers", comes "Marvel's Captain America: The Winter Soldier", the global phenomenon that teams Captain America (Chris Evans) with the Black Widow (Scarlett Johansson) and a new ally, the Falcon (Anthony Mackie), in a fight for the future of mankind. Following the cataclysmic events in New York with the Avengers, Steve Rogers, aka Captain America, is living quietly in Washington, D.C. and trying to adjust to the modern world. But when a S.H.I.E.L.D. colleague comes under attack, Steve becomes embroiled in a web of intrigue that threatens to put the entire world at risk. As the conspiracy deepens and it's no longer clear whom to trust, Captain America, Black Widow and the Falcon must join forces to overthrow their insidious enemy's most mysterious and powerful weapon yet – the Winter Soldier.
Disney/Marvel Studios deliver easily one of the best Blu-rays this year. The 1080p transfer is absolutely perfect and just visually amazing. I was disappointed not seeing it in 3D but in 2D it was just so impressive still. Same goes for the very epic DTS-HD Master Audio 7.1 surround track, which delivers an amazing experience. The film is very action packed and this works extremely well. Special features are good but not outstanding. There is a audio commentary track with Directors Anthony & Joe Russo and screenwriters Christopher Markus & Stephen McFeely, which is very extensive. "On the Front Line: An Inside Look at Captain America's Battlegrounds" takes a look into the production. "On Set with Anthony Mackie: Cut the Check!" focuses on Falcon. Steve Rogers' Notebook looks into the film's differences in various international versions of the film. Lastly there are a few deleted, extended scenes and gag reel included.
Filed Under: DVD/Blu-Ray Reviews Tagged With: america, bluray, captain, marvels, review, soldier, ...


Emily is beautiful, gorgeous – any man's dream. No wonder Adam is madly in love with her. She's something special, and so is the love between them. Each day, the newly-weds grow closer. Adam has no real friends, his work is boring, the only uplifting part of each day is going home to her – his beloved wife, Emily.
Adam is not your typical guy with all his disorders, among which OCD and a somewhat superior attitude, so unsurprisingly he doesn't have many friends. Neither has his new wife, Emily, who flew over from California only a couple of weeks ago. Adam's few friends, if you can call them that, have not been invited to the wedding. They are completely surprised by the marriage and eager to meet Emily.
Why doesn't Emily leave the house as in – ever? Why isn't Adam eager to show off his new bride but instead, acts protectively and.. dare one say.. possessively? Phoebe, Adam's ex, is furious and desperate to discover all about her rival. She is determined that one day, she will have Adam back – whatever it takes.
Nigel Cooper is a British author of fiction. He writes across a diverse range of genres including contemporary, psychological thrillers, suspense, crime and supernatural. He found his 'voice' as the editor of his own magazine, which he ran for eight years before becoming a full-time author in 2011. He studied screenwriting in London and ran a video production company before becoming a freelance journalist writing articles, reviews and stories for various newspapers and magazines.
Nigel also studied to be a private investigator and spent a year working as a PI, the knowledge of which comes in handy with his crime writing today. Having attained a degree in classical piano performance Nigel loves nothing more than to sit and play Beethoven when he isn't writing. Also, being a Hi-Fi nut and a vinyl connoisseur he can often be found in Market Hill in Cambridge browsing through the used vinyl stalls in the hope of picking up a mint condition first pressing of 'Selling England by the Pound'. Nigel lives and writes in Cambridgeshire.


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The Venezuelan foreign minister has denounced a US coup bid against the Latin American nation, after reports of US officials holding numerous secret talks with rebel officers who planned to topple the government.
"It is absolutely unacceptable and unjustifiable" for the Donald Trump administration to "encourage and promote violent actions of extremist factions" seeking to overthrow the government, Jorge Arreaza wrote on Twitter on Sunday.
The foreign minister's remarks came after multiple reports that officials in Washington are considering an ouster of Venezuelan President Nicolas Maduro, and possibly even an outright invasion of the country.
On Saturday, the New York Times reported that US officials held secret talks throughout last year with various dissidents within the Venezuelan Army, including individuals on the US' own sanctions list of corrupt officials. The White House has not explicitly denied the revelations presented in the NYT story. Instead, it merely states that the US supports Venezuela's "peaceful, orderly return to democracy." Washington continues to hear the "daily concerns of Venezuelans," said Garret Marquis, spokesperson for the White House National Security Council.
In response to mounting sanctions and criticism from Washington, the head of Venezuela's Constituent Assembly Diosdado Cabello announced that the ruling party will stage a massive "anti-imperialist" protest march against US efforts to meddle in the country's domestic affairs. The demonstration will take place in the nation's capital, Caracas, on Tuesday.
As Venezuela continues to suffer from severe shortages and hyperinflation, the US has slapped the nation with several rounds of sanctions, including restrictive measures against Venezuela's finances, which are intended to prevent it from selling its debt.


Melissa Chisena had the privilege of dancing and touring nationally with North Carolina Dance Theatre and The Richmond Ballet. Currently residing in Philadelphia, PA, has danced with Jeanne Ruddy Dance and Tania Isaac Dance. She has performed nationally at venues such as Bates Dance Festival, Jacob's Pillow, Aaron Davis Hall-Harlem Stage, Dance Place in DC, The Annenberg Center, The Suzanne Roberts Theatre, The Wilma and numerous colleges throughout the US. Her choreography has been featured at North Carolina Dance Theatre, Richmond Ballet, American Dance Festival, Regional Dance America, Ursinus College, Richard Stockton College, Philadelphia Dance Theatre, Yes! Invitational, Come Together Festival, Grounds for Sculpture and many other venues across the Northeast. She is currently a member of the NADINE Project, a collaborative choreographic company Connecticut, Stone Depot Dance Lab, Beau Hancock, The Naked Stark, Tara Madsen-Robbins, and runs her own company, Chisena Danza. She is the ballet mistress at Philadelphia Dance Theatre and teaches at Temple Univeristy, Ursinus College, Bryn Mawr College, Eastern University, Dance Elite, and Janice's Danceworks. She is the producer of An Evening of Duets, an annual professional show at the Community Education Center and The Philadelphia Youth Dance Fest, an annual youth festival featuring pre-professional companies from across the United States. She is thrilled to be performing with Naked Stark again!!
Leanne Grieger (Dancer), Leanne Grieger is originally from Long Island, NY. She has trained at the Ailey School (NY) and at the Martha Graham School of Contemporary Dance (NY). In 2006, she relocated to Philadelphia to attend the University of the Arts, and graduated in 2010 with her BFA is Modern Dance Performance. Throughout her time spent in Philly, she has worked with IdiosynCrazy Productions, Group Motion, Brian Sanders' Junk, Melina Martin (Argentina), Wally Cardona (NY), Raphael Xavier, John Luna, Gabrielle Revlock, and Nicole Bindler. Her choreography has been shown at Philly PARD's "Mixed Grille", Hybridge Arts Collective "Last Mondays", Group Motion's "Spiel Uhr", the Bookspace, and Round Theater Company's "24Hours: A Festival of New Work". In addition to The Naked Stark, Leanne is currently a performer with Cardell Dance Theater, Curt Haworth Movement and Performance, Choreosplat Dance Works, and ArcheDream for HUMANKIND.
Marisa Illingworth, a recent graduate from The University of the Arts with a BFA in Dance, is a dance artist in Philadelphia, PA. Since graduating, she has taken great pleasure in performing for local artists such as Shannon Murphy, Meredith Stapleton, Haylee Warner, Sean Thomas Boyt and Katherine Kiefer Stark. She values a heightened sense of emotional, social, and political awareness in physical practice and in every day life, and is very excited to continue learning, questioning, and collaborating with fellow artists in Philadelphia.
Chloe Marie Newton is a visual artist from California. She currently resides in Philadelphia where she received her BFA in dance from the University of the Arts in May 2017. Chloe is currently interested in creating collaborative work in hopes to translate the powerful personal histories each individual carries and how important it is to use art to navigate life.
Harlee Trautman is a movement artist and sculptor currently residing in Philadelphia, PA, though most of her artistic career has been spent in Southern Louisiana, where she received her BFA in Sculpture. Since arriving in Philadelphia, Harlee has had the opportunity to work professionally with Opera Philadelphia, Asya Zlatina & Dancers, The Naked Stark, and with several local artists including Meredith Stapleton, Mary-Carmen Webb, Raphael Xavier, Annielille Kollman, and Melissa Rector. Harlee's most recent work has been showcased at the Iron Factory(Philadelphia), Tattooed Mom's(Philadelphia), Grounds for Sculpture(Hamilton, NJ), as well as on display at the Philadelphia International Airport's D terminal.
Brionna Williams is a young independent dance artist currently residing in Philadelphia. Originally a native of Atlanta, Georgia she began dancing at the age of 2 years old. She has trained intensely in multiple styles of dance including ballet, tap, jazz, hip hop, contemporary/modern, improvisation and more. Brionna attended the Dekalb School of Performing Arts High School as a dance major and vocal/media communications minor. In 2010, she was offered a small role as a featured dancer in the Tyler Perry's "For Colored Girls" film. She received her B.F.A in Dance Education and Performance from The University of the Arts in May 2015. Brionna has performed original works of Ronen Koresh, Mark Caserta, Douglas Becker, Sharon Eyal, Robert Battle, Sidra Bell, Helen Simoneau, Netta Yerushalmy, and many others. Following graduation she took on the responsibility of Rehearsal Director at the University of the Arts during their 2015-2016 school year. Post grad she has done project based work with Virgil Gadson, Curt Haworth Janice Rosario and Company, Mark Haim, and a few others! Brionna is currently a full- time ballet instructor at L&L Dance Productions teaching ages 11-17. She is also a signed model in the commercial/print/fitness division at Model Management Group in New York.


"This doesn't fall under any genre--it's emotion, raw and rare. It's so beautiful I feel I may never hear anything so eloquent again. There are tunes Kathy and Randy cut before he left us; there are originals; there's one song I heard Kathy and Randy do on many occasions where we all laughed uproariously; but mostly, there's Kathy's voice and the feeling of loss......and unbearable beauty."


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At Scaramouche, Antonio Scaccabarozzi Tries On Rigorous Beauty
THE DAILY PIC: The Italian conceptualist couldn't help pleasing our eyes.
Blake Gopnik, October 7, 2015
MY DAILY PIC (#1406): This picture from 1980 looks like an attractive abstraction, but it isn't quite that. It is less about what it looks like than about the process that led to its look – in this case, the injection into the wet canvas of carefully calibrated quantities of pigment. The piece is by the late Antonio Scaccabarozzi, a noted Milanese artist whose work is getting its first American outing at Scaramouche gallery on the Lower East Side of New York. The survey is amazingly varied, showing the artist working through all kinds of options for how art might be made, in parallel to (maybe sometimes in conversation with) some strands in American conceptualism. In all of those options, however, you see him dealing with an ancient Italian tradition that says that beauty must come before all. He fights that tradition, while also yielding to it. (He could have chosen to make his dots an ugly brown.)
For a full survey of past Daily Pics visit blakegopnik.com/archive.
Postcards from the Edge Benefit to Offer Works from Famous Artists for Just $85
By , Oct 7, 2015
Has the Market for 'Zombie Formalists' Evaporated?


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Journal of the American Veterinary Medical Association
Reverse cumulative distributions of rabies neutralizing antibody titers 5 to 15 days after booster vaccination in dogs with a current (n = 55; solid line) or out-of-date (19; dashed line) rabies vaccination status. The reverse cumulative proportion represents, for any given titer, the proportion of dogs with a titer equal to or greater than that titer. The hypothesis test for noninferiority was significant (P = 0.029), with out-of-date dogs shown to be noninferior to current dogs.
1. Brown CM, Conti L, Ettestad P, et al. Compendium of animal rabies prevention and control, 2011. J Am Vet Med Assoc 2011; 239: 609–617.
1. Brown CM Conti L Ettestad P, et al. Compendium of animal rabies prevention and control, 2011. J Am Vet Med Assoc 2011; 239: 609–617.10.2460/javma.239.5.609)| false
2. Lau E. States consider controlling rabies vaccination intervals (2011). Veterinary Information Network. Available at: news.vin.com;VINNews.aspx?articleId=19501. Accessed Apr 23, 2014.
2. Lau E. States consider controlling rabies vaccination intervals (2011). Veterinary Information Network. Available at: news.vin.com;VINNews.aspx?articleId=19501. Accessed Apr 23, 2014.)| false
3. Smith JS, Yager PA, Baer GM. A rapid reproducible test for determining rabies neutralizing antibody. Bull World Health Organ 1973; 48: 535–541.
3. Smith JS Yager PA Baer GM. A rapid reproducible test for determining rabies neutralizing antibody. Bull World Health Organ 1973; 48: 535–541.)| false
4. World Organisation for Animal Health. Chapter 2.1.13. Rabies. In: OIE terrestrial manual. Paris: World Organisation for Animal Health, 2013;1–28. Available at: www.oie.int;fileadmin;Home;eng;Health_standards;tahm;2.01.13_RABIES.pdf. Accessed Jun 1, 2014.
4. World Organisation for Animal Health. Chapter 2.1.13. Rabies. In: OIE terrestrial manual. Paris: World Organisation for Animal Health, 2013;1–28. Available at: www.oie.int;fileadmin;Home;eng;Health_standards;tahm;2.01.13_RABIES.pdf. Accessed Jun 1, 2014.)| false
5. Mansfield KL, Burr PD, Snodgrass R, et al. Factors affecting the serological response of dogs and cats to rabies vaccination. Vet Rec 2004; 154: 423–426.
5. Mansfield KL Burr PD Snodgrass R, et al. Factors affecting the serological response of dogs and cats to rabies vaccination. Vet Rec 2004; 154: 423–426.10.1136/vr.154.14.423)| false
6. Ng TH. Non-inferiority hypotheses and choice of non-inferiority margin. Stat Med 2008; 27: 5392–5406.
6. Ng TH. Non-inferiority hypotheses and choice of non-inferiority margin. Stat Med 2008; 27: 5392–5406.10.1002/sim.3367)| false
7. Aubert MF. Practical significance of rabies antibodies in cats and dogs. Rev Sci Tech 1992; 11: 735–760.
7. Aubert MF. Practical significance of rabies antibodies in cats and dogs. Rev Sci Tech 1992; 11: 735–760.10.20506/rst.11.3.622)| false
8. Hooper DC, Morimoto K, Bette M, et al. Collaboration of antibody and inflammation in clearance of rabies virus from the central nervous system. J Virol 1998; 72: 3711–3719.
8. Hooper DC Morimoto K Bette M, et al. Collaboration of antibody and inflammation in clearance of rabies virus from the central nervous system. J Virol 1998; 72: 3711–3719.10.1128/JVI.72.5.3711-3719.1998)| false
9. Day MJ. Ageing, immunosenescence and inflammageing in the dog and cat. J Comp Pathol 2010; 142: S60–S69.
9. Day MJ. Ageing, immunosenescence and inflammageing in the dog and cat. J Comp Pathol 2010; 142: S60–S69.10.1016/j.jcpa.2009.10.011)| false
Article by Michael C. Moore
Article by Rolan D. Davis
Article by Qing Kang
Article by Christopher I. Vahl
Article by Ryan M. Wallace
Article by Cathleen A. Hanlon
Article by Derek A. Mosier
Ben Sun
Michael Auslander
Catherine M. Brown
Lisa Conti
Paul Ettestad
Mira J. Leslie
Faye E. Sorhage
Jeremy B. Evans
Andra K. Voges
Leah Pomerantz
Yu Hung (Alex) Hsieh
Victoria Van
Aliya Magee
Nathalie Rademacher
Lin-Yi Hsuan
Lisa Lipitz
Jaime E. Sage
Comparison of anamnestic responses to rabies vaccination in dogs and cats with current and out-of-date vaccination status
Michael C. Moore
Michael C. MooreVeterinary Diagnostic Laboratory, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506.
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DVM, MPH
Rolan D. Davis
Rolan D. DavisVeterinary Diagnostic Laboratory, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506.
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Qing Kang
Qing KangStatistical Intelligence Group LLC, 117 Firethorn Ln, Manhattan, KS 66503.
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Christopher I. Vahl
Christopher I. VahlDepartment of Statistics, College of Arts and Sciences, Kansas State University, Manhattan, KS 66506.
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Ryan M. Wallace
Ryan M. WallaceCDC, 1600 Clifton Rd, Atlanta, GA 30333.
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Cathleen A. Hanlon
Cathleen A. HanlonVeterinary Diagnostic Laboratory, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506.
CDC, 1600 Clifton Rd, Atlanta, GA 30333.
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VMD, PhD
Derek A. Mosier
Derek A. MosierDepartment of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506.
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https://doi.org/10.2460/javma.246.2.205
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CONTRIBUTOR NOTES
Objective—To compare anamnestic antibody responses of dogs and cats with current versus out-of-date vaccination status.
Design—Cross-sectional study.
Animals—74 dogs and 33 cats.
Procedures—Serum samples were obtained from dogs and cats that had been exposed to rabies and brought to a veterinarian for proactive serologic monitoring or that had been brought to a veterinarian for booster rabies vaccination. Blood samples were collected on the day of initial evaluation (day 0) and then again 5 to 15 days later. On day 0, a rabies vaccine was administered according to label recommendations. Paired serum samples were analyzed for antirabies antibodies by means of a rapid fluorescent focus inhibition test.
Results—All animals had an antirabies antibody titer ≥ 0.5 IU/mL 5 to 15 days after booster vaccination. Dogs with an out-of-date vaccination status had a higher median increase in titer, higher median fold increase in titer, and higher median titer following booster vaccination, compared with dogs with current vaccination status. Most (26/33) cats, regardless of rabies vaccination status, had a titer ≥ 12 IU/mL 5 to 15 days after booster vaccination.
Conclusions and Clinical Relevance—Results indicated that dogs with out-of-date vaccination status were not inferior in their antibody response following booster rabies vaccination, compared with dogs with current vaccination status. Findings supported immediate booster vaccination followed by observation for 45 days of dogs and cats with an out-of-date vaccination status that are exposed to rabies, as is the current practice for dogs and cats with current vaccination status.
Each year in the United States, approximately 6,000 cases of rabies are documented in animals, primarily in the major wildlife reservoir species (ie, raccoons, bats, skunks, and foxes). These confirmed cases are invariably associated with 1 or more human and animal exposures to rabies. In addition, many domestic animals come into contact with sick wildlife or other animals that cannot be captured for rabies diagnostic testing and, depending on the geographic location and species of animal involved, may be considered potentially exposed to rabies. As a result, thousands of dogs and cats are known to be exposed or are potentially exposed to rabies each year in the United States.
Regulations have been developed to minimize the public health risks that dogs and cats exposed or potentially exposed to rabies and potentially incubating the virus may pose. These regulations vary, depending on locality, but most public health officials refer to or rely on the Compendium of Animal Rabies Prevention and Control1 for guidance in these situations.
According to the current version of the compendium, dogs and cats with current rabies vaccination status that have been exposed to an animal confirmed or suspected to be rabid should immediately receive a rabies booster vaccination and be observed for 45 days, most often, as allowed by jurisdictional authorities, under the owner's supervision with no contact restrictions. The recommendation for dogs and cats that have never been vaccinated against rabies and that have been exposed to a rabid animal is euthanasia or quarantine for 6 months in a specialized facility.
In contrast, the compendium guidelines are less clear when it comes to recommendations for dogs and cats overdue for a booster vaccination (ie, dogs and cats with out-of-date rabies vaccination status), suggesting that these animals be evaluated on a case-by-case basis that takes into account the severity of the exposure, time since the last rabies vaccination, number of rabies vaccinations received previously, current health status of the animal, and local rabies epidemiology.1 Unfortunately, this recommendation for a case-by-case risk assessment coupled with concerns for public safety, a fear of liability, and the lack of published clinical data regarding response to rabies vaccination in dogs and cats with an out-of-date rabies vaccination status commonly leads to conservative handling of these animals. Most often, this means that public health officials consider these animals to be unvaccinated, resulting in either euthanasia or a 6-month quarantine.
The present study was designed to provide greater insight into the appropriate handling of dogs and cats with out-of-date rabies vaccination status that have been exposed to rabid animals. Specifically, the purpose of the study reported here was to compare anamnestic antibody responses of dogs and cats with current versus out-of-date rabies vaccination status.
Sample acquisition—The first phase of the study involved serum samples from 10 dogs and 2 cats, from 8 states, that had been exposed to rabies and for which the attending veterinarian or owner had contacted the Rabies Diagnostic Laboratory at Kansas State University between March 2010 and June 2012 for help in assessing the immune state of the animal. The remainder of the study involved serum samples from an additional 64 dogs and 31 cats that had been exposed to rabies and brought to a veterinarian for proactive serologic monitoring or that had not been exposed to rabies and had been brought to a veterinarian for booster rabies vaccination. In total, serum samples from 74 dogs and 33 cats from 13 states collected over a period of 3.75 years were included. The study protocol was approved by the Kansas State University Institutional Animal Care and Use Committee (protocol No. 3193).
For each animal included in the study, a 2-mL serum sample was obtained at the time of initial evaluation (day 0) and then again 5 to 15 days later. On day 0, a rabies vaccine of the attending veterinarian's choice was administered to the animal according to label recommendations. Serum samples were shipped fresh to the Rabies Diagnostic Laboratory and analyzed for antirabies antibody titer by means of a rapid fluorescent focus inhibition test.
Classification of rabies vaccination status—All dogs and cats included in the study were classified as having a current or out-of-date rabies vaccination status. Rabies vaccination status was classified as current if the animal had received initial rabies vaccination and the initial (ie, day 0) serum sample was obtained < 1 year after the initial vaccination or if the animal had received both an initial rabies vaccination and a rabies booster vaccination and the initial (day 0) serum sample was obtained < 3 years after the last vaccination. Otherwise, rabies vaccination status was classified as out of date.
A cutoff of 3 years since the last vaccination was used regardless of whether the last vaccine administered had been licensed for a 1-year or 3-year duration, because the antigenic mass, carrier, adjuvant, and other characteristics of 1-year and 3-year vaccines from 2 companies2,a were reportedly identical. One animal that received a 1-year vaccine was excluded from the data analysis because the companyb that manufactured the vaccine would neither confirm nor deny that their 1-year and 3-year formulations were identical.
Rapid fluorescent focus inhibition test—The rapid fluorescent focus inhibition test,3 a serum neutralization test, was used to determine the titer of rabies neutralizing antibodies in all serum samples. Briefly, rabies virus was mixed with serial dilutions of each serum sample, and the resulting mixture was incubated at 37°C for 90 minutes. Baby hamster kidney cells suspended in Eagle minimum essential medium with 10% fetal bovine serum were then added, and the mixture was incubated for 20 to 24 hours at 37°C. Following fixation with 80% acetone, a conjugate of antirabies antibody labeled with fluorescein isothiocyanate was added to the cells. After washing, cells were counted by means of fluorescent microscopy to determine the ratio of infected to noninfected cells at each dilution. Results were compared with results for a standard control sample containing a known neutralizing antibody concentration to determine the titer for each test sample.
End point dilution was not used to determine the specific antibody titer for samples that resulted in complete neutralization of the virus at the highest serum dilution used. However, the maximum possible titer varied between test runs depending on the control sample's ability to neutralize the challenge virus. Standard operating procedures for the test method defined a priori an acceptable range of titers for the control sample, with testing repeated if the titer for the control sample was outside the acceptable range. Because the lowest titer for control samples used in the present study was 12 IU/mL, for calculation purposes, we reported results for test samples > 12 IU/mL as 12 IU/mL. In the statistical analysis, all titers reported as ≥ 12 IU/mL were treated as right censored. For comparison, a rabies neutralizing antibody titer ≥ 0.5 IU/mL is considered by the World Health Organization to be an adequate vaccine response for dogs and cats traveling to rabies-free areas.4
Data analysis—Rabies neutralizing antibody titers following booster vaccination (ie, days 5 to 15) were compared between dogs with current versus out-of-date vaccination statuses by modeling the proportions of animals with titers exceeding various given values (sometimes referred to as a reverse cumulative distribution). This approach was selected to account for the right censoring of titers for some animals. A proportional hazards modelc was used to compare distributions of titers between the 2 groups (current vaccination status versus out-of-date vaccination status), with current vaccination status as the reference. In essence, the proportional hazards ratio represented the comparative ability of the 2 groups to reach a particular titer after booster vaccination on day 0. If the ratio was equal to 1, the 2 groups were considered identical. If the ratio was > 1, then the response to booster vaccination in animals with an out-of-date vaccination status was considered to be not as robust as the response in animals with a current vaccination status. Conversely, if the ratio was < 1, the response to booster vaccination in animals with an out-of-date vaccination status was considered superior to the response in animals with a current vaccination status. For purposes of the present study, we assumed the response to booster vaccination in animals with an out-of-date vaccination status was not clinically worse than the response in animals with a current vaccination status if the hazard ratio was < 1.25. On the basis of an analysis of data from Mansfield et al,5 this choice of noninferiority margin was determined to be conservative. Formally, in the hypothesis test of noninferiority, the null hypothesis was that the ratio was ≥ 1.25 (ie, out-of-date vaccination status was inferior to current vaccination status), and the alternative hypothesis was that the ratio was < 1.25 (ie, out-of-date vaccination status was noninferior to current vaccination status). Diagnostic graphs indicated the proportional hazard model was appropriate for these data.
Rabies neutralizing antibody titers for the 10 dogs and 2 cats in the first phase of the study were summarized (Table 1). For all 12 animals, antibody titers 5 to 15 days after booster vaccination were > 0.5 IU/mL. Five of the animals were classified as having a current vaccination status, and 7 were classified as having an out-of-date vaccination status. All 7 animals with an out-of-date vaccination status and 2 animals with a current vaccination status were quarantined for 6 months, during which time no rabies-associated clinical disease was reported. All 12 animals survived following rabies exposure. The 2 animals with current vaccination status that were quarantined had been exposed > 1 year (but < 3 years) after receiving a rabies vaccine labeled for 1-year duration. However, the manufacturer confirmed that the 1-year and 3-year formulations of this product were identical; therefore, for purposes of the present study, both animals were classified as having a current vaccination status.
Rabies neutralizing antibody titers immediately prior to (baseline) and 5 to 15 days after booster vaccination in 10 dogs and 2 cats that had been exposed to an animal confirmed or suspected to be rabid.
Exposure description
> 1 vaccine dose previously
Label duration of last vaccine (y)
Time since last vaccination (mo)
Rabies vaccination status
Baseline titer (IU/mL)
Titer after booster vaccination (IU/mL)
Dog* Contact with skunk Yes 3 39.0 OOD 9.7 12
Dog Exposed to rabid skunk Yes UK 9.0 C 0 12
Dog* Raccoon bite Yes 3 41.4 OOD 12 12
Dog* Raccoon bite Yes 1 18.1 C 0.7 3.4
Dog* Exposed to rabid skunk No 1 36.0 OOD 0.6 12
Dog Exposed to rabid skunk Yes 3 15.6 C 12 12
Dog* Raccoon bite Yes 1 30.5 C 1.8 12
Dog Exposed to rabid skunk Yes 3 10.7 C 3.1 12
Cat* Raccoon bite Yes 3 38.7 OOD 0.3 12
Cat* Exposed to bat Yes 3 44.9 OOD 12 12
* Quarantined for 6 months after rabies exposure; no animals developed signs of rabies-associated disease during quarantine, and all 12 animals survived.
C = Current. OOD = Out of date. UK = Unknown.
Rabies vaccination status was classified as current if the animal had received an initial rabies vaccination and the initial serum sample was obtained < 1 year after the initial vaccination or if the animal had received both an initial rabies vaccination and a rabies booster vaccination 1 year later and the baseline serum sample was obtained < 3 years after the last vaccination. Otherwise, rabies vaccination status was classified as out of date. A cutoff of 3 years since the last vaccination was used regardless of whether the last vaccine administered had been licensed for a 1-year or 3-year duration, because formulations of the 1-year and 3-year vaccines were confirmed by the manufacturer to be identical.
Rabies neutralizing antibody titers before (day 0) and after (day 5 to 15) booster vaccination for all 74 dogs and 33 cats included in the study were summarized, along with median increase in titer and median fold increase (Table 2). Dogs with out-of-date vaccination status had a higher median increase in titer, higher median fold increase in titer, and higher median titer following booster vaccination, compared with dogs with current vaccination status. However, statistical analyses were not performed on these parameters.
Rabies neutralizing antibody titers immediately before (baseline) and 5 to 15 days after booster vaccination in 74 dogs and 33 cats classified as having a current or out-of-date rabies vaccination status.
Species and vaccination status
Baseline titer (IU/mL)*
Titer after booster vaccination (IU/mL)*
Median increase (IU/mL)
Median fold rise
Current (n = 55) 2.6 (0–12) 11.1 (0.5–12) 3.1 0
Out of date (n = 19) 2.0 (0–12) 12.0 (0.5–12) 8.1 2
Current (n = 7) 2.4 (0.1–12) 12.0 (2.6–12) 9.4 2
Out of date (n = 26) 6.3 (0.3–12) 12.0 (2.9–12) 2.4 0
* Data are given as median (range).
See Table 1 for remainder of key.
The percentages of dogs and cats in each vaccine category with titers that equaled or exceeded various benchmarks above 0.5 IU/mL were summarized (Table 3). All animals in the study had a titer ≥ 0.5 IU/mL 5 to 15 days after booster vaccination. This included the 14 dogs (9 with current vaccination status and 5 with out-of-date vaccination status) and 2 cats (1 with current vaccination status and 1 with out-of-date vaccination status) that had titers < 0.5 IU/mL prior to booster vaccination (day 0; Table 4). Median increase in titer for dogs (Table 5) and cats (Table 6) with an out-of-date vaccination status was higher for those that had previously received only a single dose of vaccine, compared with those that had previously received ≥ 2 doses of vaccine. Again, however, no statistical analyses were performed on this parameter.
Number (percentage) of dogs and cats in Table 2 with rabies neutralizing antibody titers 5 to 15 days after booster vaccination that equaled or exceeded various benchmarks above 0.5 IU/mL.
Titer (IU/mL)
Current (n = 55) 55 (100) 53 (96) 50 (90) 40 (72) 34 (61) 26 (47)
Out of date (n = 19) 19 (100) 18 (94) 18 (94) 16 (84) 13 (68) 13 (68)
Current (n = 7) 7 (100) 7 (100) 7 (100) 6 (85) 6 (85) 6 (85)
Out of date (n = 26) 26 (100) 26 (100) 26 (100) 23 (88) 23 (88) 21 (80)
Data are given as number (%).
Rabies neutralizing antibody titers immediately before (baseline) and 5 to 8 days after booster vaccination in 14 dogs and 2 cats with a titer < 0.5 IU/mL prior to booster vaccination.
Time between samples (d)
Out of date 0.2 8 12
0.4 7 2.4
Current 0 7 12
0.3 5 11.1
Current 0.1 6 12
Median titer after booster vaccination was 12 IU/mL for dogs with an out-of-date vaccination status and 4 IU/mL for dogs with a current vaccination status.
See Table 2 for key.
Rabies neutralizing antibody titers immediately before (baseline) and 5 to 15 days after booster vaccination for 15 dogs with an out-of-date vaccination status classified on the basis of number of rabies vaccinations received previously.
No. of vaccine doses received previously
Time overdue for vaccination (mo)
Increase in titer (IU/mL)
≥ 2 0.6 6 2.8 0.2 2.2
0.4 7 2.4 0.3 2
9.7 15 12 3 2.3
4 7 5.9 4.8 1.9
12 6 12 7.5 0
3.9 7 12 10.6 8.1
2.9 7 7.8 14.9 4.9
0 8 0.5 19.7 0.5
2 7 12 22.8 10
1 3.4 7 12 0.3 8.6
0.6 10 12 3.4 11.4
0.2 8 12 3.6 11.8
0 5 12 5.9 12
0.6 7 12 24 11.4
Median increase in titer was 2.2 IU/mL for dogs that had previously received ≥ 2 doses of vaccine and was 11.6 IU/mL for dogs that had previously received only a single dose of vaccine.
Rabies neutralizing antibody titers immediately before (baseline) and 5 to 15 days after booster vaccination for 24 cats with an out-of-date vaccination status classified on the basis of number of rabies vaccinations received previously.
≥ 2 12 8 12 0.1 0
6.1 7 11.3 0.1 5.2
3.4 7 12 0.2 8.6
6.4 7 9 1.1 2.6
3.4 7 3.7 2.9 0.3
1 0.6 5 12 4.9 11.4
Median increase in titer was 0.3 IU/mL for cats that had previously received ≥ 2 doses of vaccine and was 9.3 IU/mL for cats that had previously received only a single dose of vaccine.
Reverse cumulative distributions of titers 5 to 15 days after booster vaccination were calculated for dogs with current vaccination status and dogs with out-of-date vaccination status (Figure 1). The hypothesis test for noninferiority was significant (P = 0.029), with out-of-date dogs shown to be noninferior to current dogs, and the proportional hazards ratio (with current vaccination status as the reference) was 0.53 (95% confidence interval, 0.20 to 1.12). Because the upper limit of the 95% confidence interval was < 1.25, the response to booster vaccination in dogs with an out-of-date vaccination status was considered to be noninferior to the response in dogs with a current vaccination status.
Citation: Journal of the American Veterinary Medical Association 246, 2; 10.2460/javma.246.2.205
Because of the small number of cats in the study and the fact that most cats, regardless of whether they had a current (6/7) or out-of-date (21/26) vaccination status, had a titer ≥ 12 IU/mL 5 to 15 days after booster vaccination, proportional hazards analysis could not be used to analyze the response to booster vaccination in cats with current versus out-of-date vaccination status.
Results of the present study indicated that the anamnestic responses of dogs and cats with an out-of-date rabies vaccination status were similar to the responses in animals with a current rabies vaccination status. Specifically, titers 5 to 15 days after booster vaccination in dogs with an out-of-date vaccination status were shown to be noninferior to titers in dogs with a current vaccination status. Also, dogs with an out-of-date vaccination status had a higher median increase in titer, higher median fold increase in titer, and higher median titer following booster vaccination, compared with dogs with current vaccination status; however, statistical analyses were not performed to compare these parameters between groups.
The noninferiority margin of 1.25 used in the present study was selected because it has commonly been used in other studies as a conservative margin for hazard ratio analyses. On the basis of an analysis of results reported by Mansfield et al5 for dogs and cats vaccinated with 3 rabies vaccines, we determined that a margin of 1.25 corresponded to a difference in titer between animals with an out-of-date vaccination status and naïve animals that was at least 88% of the difference in titer between animals with current vaccination status and naïve animals. Ng6 recommends that the noninferiority margin preserve at least 80% of the advantage the active treatment holds over placebo. Therefore, we believe that the noninferiority margin of 1.25 used in the present study was conservative.
In the present study, we used 3 methods to compare anamnestic responses to rabies vaccination in dogs and cats with current versus out-of-date vaccination status: fold rise in titer, absolute increase in titer, and absolute titer following booster vaccination. Evaluating the fold rise in titer gives an advantage to animals with a low starting titer. Therefore, because many animals in the present study with an out-of-date vaccination status had lower starting titers, we were not surprised that they had a higher fold rise in titer, compared with animals with a current vaccination status.
Although absolute increase in titer following booster vaccination provides some information on the anamnestic response to vaccination, it may not represent a true measure of protection. Assuming that neutralizing antibody titer is a measure of protection,7,8 then a rabies neutralizing antibody titer of 5.5 IU/mL should afford better protection than a titer of 0.5 IU/mL. However, when evaluating absolute increase in titer, an increase from 0.1 to 0.5 IU/mL is the same as an increase from 5.1 to 5.5 IU/mL.
In contrast to fold rise or absolute increase in titer, absolute titer following booster vaccination should provide a good indication of the level of protection achieved. In the present study, we found that the response for dogs with an out-of-date vaccination status was noninferior to the response for dogs with a current vaccination status (P = 0.029). Unfortunately, we could not perform the same analyses for cats in the present study because of the low number of cats enrolled and the fact that most cats, regardless of whether they had a current or out-of-date vaccination status, achieved the maximum titer (≥ 12 IU/mL) after booster vaccination. Given these high titers, even if a difference had been found between groups, it likely would not have been clinically meaningful.
Results of the present study may help clarify recommendations in the Compendium of Animal Rabies Prevention and Control1 for postexposure management of dogs and cats overdue for a booster vaccination that are exposed to an animal confirmed or suspected to be rabid. Currently, the guidelines recommend that such animals be evaluated on a case-by-case basis on the basis of the following 5 criteria: severity of the exposure, time since the last rabies vaccination, number of rabies vaccinations received previously, current health status of the animal, and local rabies epidemiology.
Importantly, the guidelines do not recommend altering postexposure management for dogs and cats with a current vaccination status on the basis of severity of the exposure. Considering that dogs and cats in the present study responded to rabies booster vaccination in a similar manner regardless of whether they had a current or out-of-date vaccination status, we believe that postexposure management should be the same for dogs and cats with current versus out-of-date vaccination status, regardless of the severity of exposure.
With respect to time since the last rabies vaccination, we did not identify a difference in anamnestic response between animals with current versus out-of-date vaccination status. In fact, dogs with an out-of-date vaccination status generally had higher responses than did dogs with a current vaccination status.
Similarly, with respect to the number of rabies vaccinations received previously, we did not find a substantial difference in anamnestic responses between dogs and cats that had previously received only a single dose of vaccine and those that had received ≥ 2 doses previously. However, age could have been a confounding factor, given that animals vaccinated only once had a median age of 3 years, whereas animals vaccinated multiple times had a median age of 6 years, and immunosenescence in dogs and cats is well documented.9
We did not evaluate the effect of health status on anamnestic responses in the present study, and all animals were generally healthy. However, we recommend that, regardless of vaccination status, public health officers should be cautious when managing immunocompromised dogs and cats that have been exposed to rabid animals.
Finally, in suggesting that public health officials take local rabies epidemiology into consideration in the postexposure management of dogs and cats with an out-of-date vaccination status that have been exposed to an animal suspected to be rabid, the compendium acknowledges that although rabies is endemic in the United States, the incidence varies widely from one location to the next. Thus, without confirmatory testing, the risk that a dog bitten by a wild raccoon has truly been exposed to rabies is much lower in, for example, Illinois than in Alabama. Nevertheless, given that the response to rabies booster vaccination in the present study was similar regardless of rabies vaccination status, we believe that postexposure management should be the same.
In conclusion, results of the present study indicated that the anamnestic response to rabies booster vaccination in dogs and cats with an out-of-date vaccination status is similar to the response for dogs and cat with a current vaccination status. Thus, we believe that postexposure management of any previously vaccinated dog or cat exposed to a confirmed or suspected rabid animal should be the same, regardless of vaccination status. Specifically, we believe that appropriate postexposure management for dogs and cats with an out-of-date vaccination status is immediate booster vaccination followed by observation for 45 days, rather than euthanasia or quarantine for 6 months. If additional reassurance is needed, titers could be measured prior to and again 5 to 7 days after booster vaccination to determine whether an anamnestic response has occurred.
Rainforth R, Merck, White House Station, NJ: Personal communication, 2014.
Menardi R, Merial, Duluth, Ga: Personal communication, 2014.
Proc PHREG, SAS/STAT, version 9.3, SAS Institute Inc, Cary, NC.
This manuscript represents a portion of a thesis submitted by Dr. Moore to the Kansas State University Graduate School as partial fulfillment of the requirements for a Master of Public Health degree.
Presented to the Compendium of Animal Rabies Prevention and Control Committee of the National Association of State Public Health Veterinarians, Nashville, Tenn, June 2014.
The authors thank Drs. Sue Nelson, John Teeter, and Don Dinges for assistance in procuring samples.
Address correspondence to Dr. Moore (mcmoore@vet.k-state.edu).
https://avmajournals.avma.org/view/journals/javma/246/2/javma.246.2.205.xml


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text:
Shard Cinema
by: Evan Calder Williams
Shard Cinema tells an expansive story of how moving images have changed in the last three decades and how they changed us along with them, rewiring the ways we watch, fight, and navigate an unsteady world.
With a range that spans film, games, software, architecture, and military technologies, the book crosses the twentieth century into our present to confront a new order of seeing and making that took slow shape: the composite image, where no clean distinction can be made between production and post-production, filmed and animated, material and digital.
Giving equal ground to costly blockbusters and shaky riot footage, Williams leads us from computer-generated "shards" of particles and debris to the broken phone screen on which we watch those digital storms, looking for the unexpected histories lived in the interval between.
SKU N/A Categories Cultural Studies, Film Studies, Free Education, Philosophy
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Shard Cinema quantity
Evan Calder Williams
Evan Calder Williams is a writer and artist. He is the author of Combined and Uneven Apocalypse and Roman Letters, and his essays have appeared in Film Quarterly, Mute, The New Inquiry, La Furia Umana, World Picture, and The Journal of American Studies, amongst other publications. He is part of the editorial collective of Viewpoint Magazine and is a founding member of Thirteen Black Cats, a research and production collective for moving images. He teaches at the Center for Curatorial Studies at Bard College.
Paperback with free eBook9781910924914
Number of pages336
Holly Willis, LA Review of Books
"An appropriately fractured rumination on contemporary cinema."
Sven Lindqvist
Dig Where You Stand
Christiana Spens
Lesley-Ann Brown
Blackgirl on Mars


text:
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In some cases, spouses can figure out a compromise as to who gets which asset, and in that case you can submit a property settlement agreement to the judge and ask that it be incorporated into the final judgment of divorce. However, in other cases, spouses disagree on the character of particular pieces of property and also disagree on their value. Sometimes the parties will need to retain appraisers to value the property. If the parties are unable to agree about how to equitably divide the property, a judge will need to make the decision. Factors that the judge will consider are the duration of the marriage, what each spouse contributed to the marital estate, the spouses' needs and ages, the spouses' health, and the spouses' earning capacities. They can also consider the conduct of each spouse during the marriage.
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A Joy to Dream: Dreaming About Breakfast?
Ok... if you really know me, you know that I make cinnamon pancakes at least twice a week. We've come up with an easy way to make them unique and fun for the kids.
Put your batter in some kind of container you can draw with. (yes, you have permission to play with your food) Then go for it... you'll be surprised what fun things you'll come up with to make.
Castle... really... I could go on forever...just try it, you'll never go back to the plain round pancake again.
lol Castle?! Yeah, I guess you could get a bit carried away. ;) I love them and seriously need to try it some time!
Tracy I need to put a link to this on my blog. These pancakes are absolutely adorable!!


text:
Sloppy may refer to:

 Sloppy Thurston (1899–1973), American baseball player
 Sloppy Smurf, a Smurfs character
 Sloppy, sister of Slimey the Worm, a pet of Oscar the Grouch in the children's television series Sesame Street
 Sloppy, title character in the 2012 film Sloppy the Psychotic

See also

 Dirty (disambiguation)
 Filth (disambiguation)
 Messy (disambiguation)
 Slop (disambiguation)

redpajama_set_name: RedPajamaWikipedia


Race participants are encouraged to park in the student lot on the north side of Wheat Ridge High School, off of Holland St. and north of 37th Ave. The only way to access this lot is off of 38th Ave., as 32nd Avenue will be closed to traffic.
The start line is on 32nd Avenue directly in front of Wheat Ridge High School.
Thursday - Friday (Sept. 12-13) 9:00 a.m. to 5:00 p.m.
Participants who register on race morning cannot be guaranteed a t shirt.
Elementary School Challenge: $10 Youth large, ESC shirt only (race day registration is $15) REGISTER BY NOON ON TUESDAY, SEPT. 10 TO BE INCLUDED IN YOUR SCHOOL'S TOTAL FOR THE ELEMENTARY SCHOOL CHALLENGE.
Race day registration begins at 7:30 a.m. and closes at 8:45 a.m.
Registrations by mail must be postmarked by September 6, 2019.
Online registration is open until midnight, September 13, 2019.
Off site registration is open from September 1 until noon on September 14 at Runners Roost Lakewood, 7978 W Alameda, and the Wheat Ridge Rec Center, 4005 Kipling St.
Is your business, book club, fitness group or family the "Fittest on the Farm"?
Register your group in the Fitness Challenge and then begin encouraging your employees, friends, family and others to enter the Farmers 5000 and select your group from the list of those participating. The group with the most entries to its name wins fun gifts from Wheat Ridge businesses and of course, major bragging rights. So whether you use this as a team building opportunity, a way to create awareness for your products and services, or simply a means to give back to the community, you will want to get involved!
Find your group on the drop-down menu on the registration page. Don't see your group? Go ahead and add it - it's free to join! Need more information? Contact us at michelle@rightstartevents.com.
RUNNERS PARTICIPATING ON BEHALF OF A GROUP IN THE FITNESS CHALLENGE MUST REGISTER ONLINE ONLY. ONLINE REGISTRATION CLOSES AT MIDNIGHT ON FRIDAY, SEPT. 13.
*One more thing - Elementary Schools and WRHS school groups are excluded from winning the Fitness Challenge. Instead, area elementary schools compete for the cash prizes generously donated by the Wheat Ridge Optimists in the Elementary School Challenge. WRHS school groups should encourage runners to select their group from the list of school groups and $10 of their entry will go directly to your group.
The top male and female runners will receive $100 CASH. First and second runners-up will receive a gift certificate from Runners Roost Lakewood, 7978 W. Alameda Ave, Lakewood. Overall winners are excluded from age group awards.
Top 3 male and female runners in all categories will receive a gift certificate from Apple Ridge Cafe. Age categories are 8 and under, 9-12, 13-15, every five years thereafter, 80 and over.
All entrants are eligible for prize drawings at the race finish, courtesy of area businesses (must be present to win).
This event is chip timed by Running Bears.
We would like to invite your business to partner with Wheat Ridge High School for its 36th Annual Farmers 5000. Sponsorship provides an ideal marketing prospect for your business. We offer many levels of sponsorship and opportunities for involvement and provide businesses with positive brand recognition. As a sponsor, you can be part of a fun athletic event that promotes health and wellness in our community and supports a local non-profit.
The Farmers 5000 depends on volunteers for many aspects of the race, including planning and coordination as well as race day logistics and operations. If you are interested in helping the Wheat Ridge High School community by volunteering for the Farmers 5000, please use the contact form at the top of the page, or use the button below. Thank you for your support of this wonderful event.


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Home Music Country Music
July 5, 2017 10:32PM ET
Shania Twain Reveals New Album Track List
Singer uses Instagram to unveil the 16 songs that make up 'Now,' her long-awaited comeback album
Joseph Hudak
Senior Editor, Rolling Stone Country
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Shania Twain has announced the track list for her comeback album Now. The Nineties country game-changer took to Instagram to post a short video revealing the 16 songs that make up her new LP, set to be released September 29th. "Feels so great to share with you the full tracklisting for my new album #ShaniaNOW!" Twain wrote, pairing the clip with a snippet of her new song "Poor Me," which evokes the Chainsmokers' "Don't Let Me Down."
"Swingin' With My Eyes Closed," a new song Twain debuted on NBC's Today Show in June, opens the album. Other titles include "Light of My Life," "Poor Me," "Who's Gonna Be Your Girl" and "Because of You." According to a June press release, Now was to be issued in two versions: a 12-track standard and a 16-track deluxe. If that remains the case, then "Life's About to Get Good" – Twain's current single – will only appear on the deluxe version. (UPDATE: Interestingly, the four bonus tracks that appear on the deluxe version of Now – "Let's Kiss and Make Up," "Where Do You Think You're Going," "Because of You" and "All in All" – will be inserted within the standard issue track list, not tacked on at the end, which changes the sequence and flow of the standard version. See the track lists below.)
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Last month, the singer shared the album cover for Now, a black-and-white photo that evokes vintage-era Twain in leopard-spotted above-the-elbow gloves.
Twain has said that writing the songs for Now was akin to therapy for the 51-year-old Canadian. Over what she called a dark period of her life, she divorced husband and producer Mutt Lange, lost her voice and struggled with a Lyme disease diagnosis, eventually purging the painful time through songwriting. "It helped me come to terms with a lot of things emotionally," she told Rolling Stone in February. "It's sort of like when you finish crying. When you're done, you're done and you move on."
Here's the deluxe track list for Now:
1. "Swingin' With My Eyes Closed"
2. "Home Now"
3. "Light of My Life"
4. "Poor Me"
5. "Who's Gonna Be Your Girl"
6. "More Fun"
7. "I'm Alright"
8. "Let's Kiss and Make Up"
9. "Where Do You Think You're Going"
10. "Roll Me on the River"
11. "We Got Something They Don't"
12. "Because of You"
13. "You Can't Buy Love"
14. "Life's About to Get Good"
15. "Soldier"
16. "All in All"
Here's the standard track list for Now:
8. "Roll Me on the River"
9. "We Got Something They Don't"
In This Article: Shania Twain


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Volunteering with the Multiple System Atrophy Trust
Volunteers are a fundamental part of our organisation and are vital for the delivery of our services. Our volunteers help us to raise awareness of MSA and help tackle the isolation felt by having a rare disease. As a charity funded entirely by donations from individuals, companies and charitable trusts, local volunteers also support us by raising vital funds to allow us to continue our work.
We accept applications from anyone with an interest in supporting those affected by MSA and welcome applications from anyone who has personal experience of MSA.
Whatever your strengths are, we're sure that we will have something that will interest you and make a huge difference to the work that we do.
Could you lend a hand? With only a small team of staff working tirelessly to raise funds, increase awareness and support people affected by MSA, we are incredibly lucky to have an ever growing army of volunteers registered to offer their time to support the Trust and get involved in our work.
Click here to view a brief descriptions of the current volunteering opportunities at the MSA Trust. The positions available in locations around the UK and Ireland vary depending on local need, but we welcome all enquiries. For more information on the roles and to apply please contact volunteer@msatrust.org.uk.
If you have a particular interest or area you feel you can help with that isn't detailed below, please do get in touch to have a conversation with our team.
Already a volunteer?
If you're already volunteering with us, you can find all of the information and resources you will need to help you in your role here.
"Our volunteers are at the heart of our work and at the heart of every community so that people affected by MSA receive the support they need. We are committed to ensuring volunteers received the best possible experience whilst volunteering and that they feel fulfilled and valued."
Karen Walker – MSA Trust CEO
Volunteering Roles at the MSA Trust
What Roles are available at the MSA Trust? Below are brief descriptions of the current...
If you're already a volunteer with the Trust here are some resources to support you...