text:
var FormController = (function () {

  var _addEventHandlers = function () {
    $("#load-data-button").click(initializeLem2);
    $("#induce-rules-button").click(invokeLem2);
    $("input[name='dataset-options']").change(updateDataInputField);
  };

  var updateDataInputField = function () {
    var dataInputField = $("#data-input");
    var dataUrl;

    switch (this.id) {
      case "dataset-1":
        dataUrl = "data/example-1.csv";
        break;
      case "dataset-2":
        dataUrl = "data/example-2.csv";
        break;
      case "dataset-set":
        dataUrl = "data/example-set-1.csv";
        break;
      default:
        dataInputField.val("");
        return;
    }

    $.ajax({
      type: "GET",
      url: dataUrl,
      dataType: "text",
      success: function (data) {
        dataInputField.val(data);
      }
    });
  }

  var convertCsv = function () {
    var csvInput = $("input[name='dataset-options']:checked").val();
    var parseConfig = {
      skipEmptyLines: true,
      complete: function (results) {
        verifyCsv(results);
      }
    };

    if (csvInput !== "dataset-file") {
      var csvRaw = $("#data-input").val();
      Papa.parse(csvRaw, parseConfig);
      return;
    }

    var selectedFile = $("#input-file")[0].files[0];
    if (selectedFile) {
      Papa.parse(selectedFile, parseConfig);
    }
  };

  var verifyCsv = function (csv) {
    if (csv.errors.length) {
      showParseErrors(csv.errors);
      return;
    }

    LEM2.initialize(csv.data);
    newConceptModal();
    $("#concept-modal").modal();
  };

  var showParseErrors = function (errors) {
    var errorList = $("<ul/>");
    errors.forEach(function (error) {
      console.error(error);
      var row = $("<span/>", {
        "text": error.row,
        "class": "badge"
      })

      var errorMessage = " " + error.code + ": " + error.message;
      var errorItem = $("<li />", {
        "text": errorMessage
      });

      errorItem.prepend(row);
      errorList.append(errorItem);
    });

    $("#data-input-error-message").append(errorList);
    $("#data-input-error-alert").show();
  };

  var newConceptRadioButton = function (concept, conceptIndex) {

    // Radio Button

    var radioButtonContainer = $("<div/>", {
      "class": "radio"
    });
    var radioButtonLabel = $("<label/>", {
      "text": "(" + concept.decision + ", " + concept.value + ")"
    });
    var radioButton = $("<input/>", {
      "type": "radio",
      "name": "concept",
      "id": "concept-" + conceptIndex,
      "value": conceptIndex
    });

    radioButtonLabel.prepend(radioButton);
    radioButtonContainer.append(radioButtonLabel);

    // Concept Cases

    var conceptCasesButton = $("<span/>", {
      "class": "badge pull-right",
      "style": "cursor:pointer;",
      "text": concept.cases.size
    });
    var conceptCases = $("<p/>", {
      "text": concept.cases.toString(),
      "style": "display: none; word-wrap: break-word;"
    });

    $(conceptCasesButton).click(function () { conceptCases.toggle(); });

    radioButtonContainer.append(conceptCasesButton);
    radioButtonContainer.append(conceptCases);

    return radioButtonContainer;
  };

  var newConceptModal = function () {
    var conceptModalBody = $("#concept-modal-form");
    conceptModalBody.empty();

    LEM2.datasetConcepts.forEach(function (concept, conceptIndex) {
      var radiobutton = newConceptRadioButton(concept, conceptIndex);
      conceptModalBody.append(radiobutton);
    });

    conceptModalBody.validate({
      errorClass: "text-danger",
      errorPlacement: function (error, element) {
        error.appendTo(element.closest("form"));
      },
      rules: {
        concept: {
          required: true
        }
      }
    });
  };

  var showRules = function (rules) {
    var rulesContainer = $("#rules-div");
    var ruleList = $("<ol/>", {
      "id": "rules-list"
    });

    rules.forEach(function (rule) {
      var ruleItem = $("<li/>");
      var warningIcon = $("<i/>", {
        "class": "fa fa-exclamation-triangle text-warning",
        "aria-hidden": true
      });

      if (!rule.consistent) {
        ruleItem.append(warningIcon);
        $("#inconsistent-alert").show();
      }

      rule.conditions.forEach(function (condition, conditionIndex) {
        var condition = " (" + condition.attribute + ", " + condition.value + ") ";
        ruleItem.append(condition);

        if (conditionIndex === rule.conditions.length - 1) {
          return false;
        }

        var upArrow = $("<i/>", {
          "class": "fa fa-chevron-up",
          "aria-hidden": true
        });
        ruleItem.append(upArrow);
      });

      var rightArrow = $("<i/>", {
        "class": "fa fa-long-arrow-right",
        "aria-hidden": true
      });
      ruleItem.append(rightArrow);

      var decision = " (" + rule.decision.name + ", " + rule.decision.value + ")";
      ruleItem.append(decision);

      ruleList.append(ruleItem);
    });

    rulesContainer.append(ruleList);
    rulesContainer.show();
  };

  var initializeLem2 = function (data) {
    $("#rules-div").hide();
    $("#inconsistent-alert").hide();
    $("#data-input-error-alert").hide();
    $("#data-input-error-message").empty();
    $("#rules-list").remove();
    convertCsv();
  };

  var invokeLem2 = function () {
    if (!$("#concept-modal-form").valid()) {
      return;
    }

    $("#concept-modal").modal("hide");

    var conceptIndex = $("input[name='concept']:checked").val();
    var concept = LEM2.datasetConcepts[conceptIndex];

    $("#concept-display").text("(" + concept.decision + "," + concept.value + ")");
    LEM2.invokeProcedure(concept);
    showRules(LEM2.singleLocalCovering);
  };

  return {
    addEventHandlers: _addEventHandlers
  };

})();

$(document).ready(FormController.addEventHandlers);


text:
Brisley, Weber among champions at Florida Net Four-Ball
by Florida State Golf Association
see also: View results for Florida Net Four-Ball, Lake Jovita Golf & Country Club
Florida Net Four-Ball winers (FSGA photo)
LAKE BUENA VISTA, Fla. (Dec. 2, 2018) - Three teams were crowned champions at the Men's Net Four-Ball Championship on Sunday at Walt Disney World's Magnolia Course. Patrick Brisley and Andy Weber were the champions in the under-50 division. Arne Victorine and Kevin Hewlett took the title in the 50-64 division, while Brian Carroll and Dennis Natale won the 65-and-over division.
Brisley and Weber prevailed in the under-50 division by carding an 11-under 133 over the two-day championship. Brisley and Weberheld fired a 7-under 65 on Saturday to take a one-stroke lead into the final round. The pair shot a 4-under 68 on Sunday to capture the title. This was Weber's second FSGA championship of the 2018 season. He won the Men's Net Championship in September.
In the 50-64 age division, Victorine and Hewlett were the champions, after shooting the low round of the day on Saturday, 10-under 62. The pair shot a 6-under 66 on Sunday to finish the championship with a 16-under 128.
After two rounds, the 65-and-over division came out to a three-way tie. Carroll and Natale, James C. Weed and Dwaine Zitko, and Kevin Hyman and David Norka all finished the championship with a 14-under 130. Carroll and Natale captured the championship in a scorecard playoff with a final-round score of 9-under 63. The pair was in sixth place following an opening round 5-under 67 but went on to card the lowest round of the day on Sunday to take the title.
View results for Florida Net Four-Ball
ABOUT THE Florida Net Four-Ball
Teams of two play in the Four-Ball Championship of 36 holes of net stroke play. Entrants must both be members of the FSGA. Three age divisions: Under 50, 50-64, and 65+.

redpajama_set_name: RedPajamaCommonCrawl


text:
Q: Make timeout work for LWP::UserAgent HTTPS Solution
As reported by @limulus in the answer I accepted, this was a bug in Net::HTTPS version 6.00. Always be wary of fresh .0 releases. Here's the relevant diff between the buggy and fixed version of that module:
D:\Opt\Perl512.32 :: diff lib\Net\HTTPS.pm site\lib\Net\HTTPS.pm
6c6
< $VERSION = "6.00";
---
> $VERSION = "6.02";
75,78c75,80
< # The underlying SSLeay classes fails to work if the socket is
< # placed in non-blocking mode.  This override of the blocking
< # method makes sure it stays the way it was created.
< sub blocking { }  # noop
---
> if ($SSL_SOCKET_CLASS eq "Net::SSL") {
>     # The underlying SSLeay classes fails to work if the socket is
>     # placed in non-blocking mode.  This override of the blocking
>     # method makes sure it stays the way it was created.
>     *blocking = sub { };
> }

Original question
Relevance: It is annoying to see your HTTPS client block indefinitely because the connection endpoint is unreliable.
This experiment is easy to set up and replay at home. You just need two things, a tarpit to trap an incoming client, and a Perl script. The tarpit can be set up using netcat:
nc -k -l localhost 9999 # on Linux, for multiple requests
nc -l -p 9999 localhost # on Cygwin, for one request only

Then, point the script to this tarpit:
use strict;
use LWP::UserAgent;
use HTTP::Request::Common;

print 'LWP::UserAgent::VERSION  ', $LWP::UserAgent::VERSION, "\n";
print 'IO::Socket::SSL::VERSION ', $IO::Socket::SSL::VERSION, "\n";

my $ua = LWP::UserAgent->new( timeout => 5, keep_alive => 1 );
$ua->ssl_opts( timeout => 5, Timeout => 5 ); # Yes - see note below!
my $rsp = $ua->request( GET 'https://localhost:9999' );
if ( $rsp->is_success ) {
  print $rsp->as_string;
} else {
  die $rsp->status_line;
}

What is this going to do? Well, connect to the port opened by NetCat, and then ... hang. Indefinitely. At least in terms of developer time. I mean it might time out after ten minutes or two hours, but I haven't checked; the specified timeout doesn't take effect, not on Linux, and not on Windows (Win32, haven't checked Cygwin).
Versions used:
LWP::UserAgent::VERSION  6.02
IO::Socket::SSL::VERSION 1.44
# on Linux

LWP::UserAgent::VERSION  6.02
IO::Socket::SSL::VERSION 1.44
# on Win32

Now for the timeout and Timeout parameters. The former is the name of the parameter for LWP::UA, the latter is the name for IO::Socket::SSL, used via LWP::Protocol::https. (Incidentally, why is metacpan HTTPS? Well, at least it's not a tarpit.) I am somehow hoping to have these parameters passed along :)
Just so you know, keep_alive doesn't have anything to do with the timeout not working, I verified that empirically. :)
Anyway, before digging deeper, does anyone know what's going on here and how to make the timeout work with HTTPS? Hard to believe I'm the first person running into this.

A: This is a result of the Net::HTTPS module overriding the blocking method of IO::Socket with a noop. Upgrading to the latest Net::HTTP package should fix this.

A: The timeout (and Timeout) options apply only to the connection -- how many seconds will LWP::UserAgent wait while connecting -- they are not for setting a timeout on the whole transaction.
You'll want to use Perl's alarm with a $SIG{ALRM} handler to timeout the whole transaction. See perldoc -f alarm or perlipc.
local $SIG{ALRM} = sub { die "SSL timeout\n" };
my $ua = LWP::UserAgent->new( timeout => 5, keep_alive => 1 );
$ua->ssl_opts( timeout => 5, Timeout => 5 );

eval {
    alarm(10);
    my $rsp = $ua->request( GET 'https://localhost:9999' );
    if ( $rsp->is_success ) {
      print $rsp->as_string;
    } else {
      die $rsp->status_line;
    }
 };
 alarm(0);
 if ($@) {
     if ($@ =~ /SSL timeout/) {
         warn "request timed out";
     } else {
         die "error in request: $@";
     }
 }

(tested on Linux. Alarms can be a bit more cantankerous in Windows/Cygwin)

A: I asked this question on PerlMonks, and received an answer to the effect that:

The underlying IO::Socket::INET does not support non-blocking sockets
  on Win32, thus non-blocking IO::Socket::SSL is not supported on Win32,
  which means also, that timeouts don't work (because they are based on
  non-blocking). See also http://www.perlmonks.org/?node_id=378675

http://cpansearch.perl.org/src/SULLR/IO-Socket-SSL-1.60/README.Win32
The PerlMonks post pointed to is from 2004. Not sure the information still applies; after all, I've seen the timeout does work on Windows, just not via SSL.

redpajama_set_name: RedPajamaStackExchange


The recycling community has actually disputed for many years over what to do with plastic container caps. The plastic sector has actually even evaluated in, attempting to set general rules, yet every regional recycling program has its very own choices.
Much of the complication with caps originates from the fact that they are made from a different plastic material compared to the bottle or jug they protect. Many caps contain polypropylene (# 5 plastic), with some (like the sport drinking bottles you take to the gym) consisting of high-density polyethylene (# 2 plastic), whereas plastic bottles, jugs and most other containers are commonly made with # 1 or # 2 plastic.
For plastic bottles, you need to ask your local recycling facility whether caps are accepted before aiming to recycle them with the container. Some will certainly ask you to leave them on, some approve caps but require them to be separated, and others will just toss them away. This range of alternatives can be quite confusing, though it is caused by the absence of any regulations concerning bottle caps. While some states like California and Massachusets made it necessary to recycle bottles, their laws have nothing to do with caps and lids. Another reason is that some facilities want to ensure that no liquid remains in the bottle, and the only way to do this is to remove caps. There are potential safety concerns that emerge when a plastic bottle is crushed with the cap on and the cap goes flying. Caps are also typically made of a plastic resin (polypropylene, or #5) that has a lower recycling commodity market than the bottles.
For plastic containers (e.g. yogurt cartons or butter tubs), the cover is usually made from the exact same material as the base. For example, if the container is # 5 plastic, chances are the material used for its cap doesn't differ. In these cases, feel free to reattach the lid before recycling if your program approves non-bottle plastics.
Assuming you left the cap on the bottle, the first step in the recycling procedure is to divide the containers as well as caps into their specific materials. iSutain Recycling facility will use a pressurized system to eliminate caps and also squash containers. Plastics are after that taken in water for a traditional float or sink test, where the container (made of # 1 plastic) will sink and also the cap (# 2 or # 5 plastic) will float.
Another step at iSutain Recycling is shredding the # 2 or # 5 plastic into flakes, which are cleaned, washed as well as dried out. Flakes are then melted into pellets, which are transferred to a producer making brand-new plastic caps or other materials, such as casing for cars and truck batteries, storage space containers or reusable plastic bags.
Plastic caps don't biodegrade, indicating it will take centuries for them to decompose in a land fill.
In America, we utilize 2.5 million plastic containers each hour, and also each of them is made with a cap.
2016 debris removal effort of Midway Atoll, an island with a population of less than 60 in the middle of the Pacific Ocean (1,300 miles from Honolulu, the closest city), found almost 5,000 bottle caps; if not recycled, these caps travel a large distance and pose a danger to marine life because of their small size.
According to the U.S. Environmental Protection Agency (EPA), plastics comprise 12% of municipal solid waste, with containers and packaging making up the largest part of that percentage. iSustain Recycling helps not only to improve ecological, but also financial situation of your particular company. If you have any questions regarding plastics recycling – contact us to get professional assistance.
Previous Post How To Recycle Kraft Paper? Next Post Waste Management In Tennessee: Are You Throwing Away Money?


1. Friday – Suncor vs Syncrude President's Cup hockey game, a United Way fundraiser. Casman Centre – doors open 6:30pm, puck drop at 7pm. Tickets $10.
4. Saturday – Habitat for Humanity Wood Buffalo Pancake Brunch – 10am-1pm at the Royal Canadian Legion in Waterways. Details found here.
5. Sunday – FILM FEAR 2016, featuring award-winning horror shorts, a costume contest, and the 20th anniversary screening of Scream. Doors open at 6:30pm, show begins at 7pm at Keyano Recital Theatre. 18+ licensed event. Tickets $13 available here.
Plus 3 new movies made it to town today. First up is Tom Cruise's latest.
We get all kinds of spooky with the second fresh film of the week: Ouija: Origin of Evil.
And finally, a comedy that looks to be a gut buster. Here's the trailer for Keeping Up With the Joneses.


Which non-slip deck to replace Treadmaster..? -… The Kipper's decks are covered in 36 year old Treadmaster. We've jet washed it, scrubbed it, acid treated it, shouted at it, hit it and soaked it.
Marine Non-Slip Boat Decking, Tape & Pads |… Results 1 - 28 of 28 . Prevent this from happening with non-slip decking materials such as boat non-slip pads or non-slip boat flooring – especially in problem.
Marine Deck Treads | Ultralon Foam Group Made from durable, closed-cell PE and EVA foam options. Ultralon deck treads are designed specifically for marine applications. UV resistant, anti-slip and non-.
Non-Slip Paint KiwiGrip | Absolute… KiwiGrip NZ & Australia - Absolute Marine Manufacturers Representative and Distributor. KiwiGrip is a non-slip marine deck coating. It is a completely durable.
Non-Skid & Vinyl Flooring -… Results 1 - 17 of 17 . Browse our selection of Non-Skid & Vinyl Flooring products at Overton's. . Boating & Marine > Carpet & Flooring > Non-Skid & Vinyl Flooring.
Deck paints on test - Practical Boat Owner 27 Nov 2014 . The results of a season's test of 6 non-slip deck paints, including International, . With most paint finishes on boats we spend hours striving for a.
Boat Non Skid | eBay GLS stock number 8100295 is a new out of the box, increment of non skid cushion mat flooring from Tracker Marine, part number 146201. Constructed from.
Non Slip Material and Slip Resistant Flooring -… Items 1 - 16 of 40 . Having non slip materials around the boat is incredibly handy. We stock a great range of non slip tape, placemats, non slip flooring for your.
TBS non-slip decking - Chandlery, Maintenance… TBS16 adhesive non-slip decking, 1.5 m. TBS 16 . TBS 10 non-slip decking for indoor or outdoor use. 10 m roll, 3 . TBS 21 : non-slip sheets to bond on deck.
Treadmaster Original Anti-Slip Decking Fitting Video -… 10 Jan 2012 . Treadmaster Original Anti-Slip Decking Fitting Video . our professional installation video of Treadmaster Marine Original boat decking and see.
Treadmaster: The Original Anti-Slip Deck Covering 5 May 2016 . . the UK, the Treadmaster range has been the benchmark for anti-slip deck coverings for over forty years. . Self Adhesive Grip Pads . Treadmaster are delighted to announce the launch of their new Marine products website.


Micky has been making people laugh for over 30 years and his act is cleverly adapted to suit any audience bringing him major success in Television, Theatre, Corporate, Cruising and Cabaret.
He shines as a stand up comic, excels in visual and vocal comedy and is experienced in production. His cheeky charm is enthusiastic and friendly with a unique act full of magic moments, brilliant parodies and deadly accurate impressions.
Micky is one of the most polished, versatile and widely renowned comedy entertainers in the country.


使用ICMP Echo Request, Echo Reply and TTL-expired.
从33434开始每送个probe依此递增,直至33434+29,(cisco router上使用extended-traceroute命令可以修改这个起始的33434 port #),同时TTL从1开始依此递增,直至1+29=30(最多送30个probe)。中间的router送回 ICMP TTL-expired,使得source得知了中间的每一个router,最后的destination送回TTL-expired 和ICMP port unreachable (因为任何主机上都没有应用使用UDP port# >32768这样的高段port#)。 所以中间某处封掉UDP port>32768回导致traceroute不工作;封掉TTL超时会使source看不到中间的router(有的router根本不支持回送TTL超时);封掉type3, code3可能看不到destination.
router每隔一秒才处理traceroute,所以在source 上你可能看到中间一路 * * *,但却看得到最后的destination.


I should be used to this by now. Every spring, my life turns from a normal working mom with a flexible social calendar into 6 months of being in "lockdown" and doing the lions share of parenting duties. But here we are again, on the eve of the switch being flipped, and I am already starting to feel shackled by my impending restrictions.
My husband works for our baseball team – which means he works EVERY home game – nights, weekends, you name it. This was not a big deal before we had a kid, but once we did, it changed everything. Anytime anyone asks me to do anything in the spring/summer/early fall I have to consult the schedule – or bring my son with, or find a sitter.
I'm a natural early riser – I like to get up early, especially in the summer when the sun is up early and I need to get out and run. Conversely, he will sleep until 9 and leave the house at 9:30am. I go to bed around 9:30 pm and typically he won't get home from a game until later than that, so we could literally go days and days living in the same house but not seeing each other.
Occasionally, I have conferences or events that I need to travel to that happen to fall over a game day(s). This does not go over with with the hubs. On those days, he has to leave work downtown, drive 20-30 min, pick him up, take him to the sitter, drive back downtown, work the game and drive back home. But we have an excellent sitter and it is what it is.
Now that my son has legit homework, that time period between him getting home from school and getting dinner on the table is downright hectic. Right now, my husband and I divide and conquer, but as soon as the season opens, it will all fall on me. He also has weekly occupational therapy sessions which we take turns going to, and now it will all be me.
I am all about travelling. I love to visit my friends & family or take trips to places I've never been. Oh, and I'm always up for a racecation! So again, when making plans of any kind or checking out possible races to run, I have to check the baseball schedule. This year, I am missing out on the Fred 200 Relay in Michigan and the Mountains to Beach Marathon in California. But this year the schedule is allowing me to go to run the Crim in my hometown of Flint, MI, and for that I am happy!
Last year, I was training for a marathon from July – October. I like to do my long runs on Sunday mornings. Unfortunately, on game days, hubby has to leave for work at 8am. That means I need to be done with all of that by then so I can stay home with our son. Once I was in that heavy mileage area – 15, 16, 18 and 20 milers – I had to really be strategic. I was getting up at 4am (partially to beat the heat too) to try to get ALL my miles in before he had to leave. A few times we even needed a sitter to cover the overlap. We don't have any family in the area to help us.
Well, there are a slight few. Everyone's first reaction when they hear who he works for is "wow, you must get to go to a lot of games". Sure, I could – if I had any interest in baseball. I take him once a year to let his co-workers see our son, and one other time usually with my team from work (but I have to pay for a sitter). My son isn't very interested in the game at this point in time, either.
The only true upside for me is lots of quality time one on one with my son. That makes up for a lot of the sacrifice. Weekends include us going out to lunch together, hitting the library together, and Saturday night movies.


text:
SCOUT B-1 R/B
ATLAS F R/B
SL-12 DEB
Track COSMOS 2080 (GLONASS Satellite in Real Time
Detailed information about COSMOS 2080 (GLONASS satellite
Designator id: 1990-045B
Description of COSMOS 2080 (GLONASS Satellite:
Cosmos 2080 was a Soviet Global Navigation Satellite System (GLONASS) satellite launched from the Baikonur cosmodrome aboard a Proton rocket. Originally established in order to locate the Soviet Union's civil aircraft and its merchant and fishing vessels, the signals were used by many American GPS system receivers as a complement/backup to the GPS system itself. The operational system contained 21 satellites in 3 orbital planes, with 3 on-orbit backups. Each satellite was identified by its slot number, which defined the orbital plane (1-8, 9-16, 17-24) and the location within the plane. The 3 orbital planes were separated 120 degrees, and the satellites within the same orbit plane by 45 degrees. The orbits were roughly circular with an inclination of about 64.8 degrees, a semi-axis of 25,440 km, and a period of 11h 15m 44s.
The 3-axis stabilized spacecraft possessed a mass of about 1,400 kg, a slight increase over the 1,250 original model. The diameter and height of the satellite bus were approximately 2.4 m and 3.7 m, respectively, with a solar array span of 7.2 m for an electrical power generation capability of 1.6 kW at beginning of life. The aft payload structure housed 12 primary antennas for L-band transmissions. Laser corner-cube reflectors were also carried to aid in precise orbit determination and geodetic research.
Launch Vehicle: Proton
Launch Site: Tyuratam (Baikonur Cosmodrome), U.S.S.R
Nominal Power: 1600.0 W
Scientific Production Association(Russia) (U.S.S.R)
1 20620U 90045B   12337.31499941  .00000059  00000-0  10000-3 0  3008
Find more details about COSMOS 2080 (GLONASS Satellite


This chapter shall be known as the "Virginia Self-Service Storage Act."
1. "Self-service storage facility" means any real property designed and used for renting or leasing individual storage spaces, other than storage spaces which are leased or rented as an incident to the lease or rental of residential property or dwelling units, to which the occupants thereof have access for storing or removing their personal property. No occupant shall use a self-service storage facility for residential purposes.
2. "Owner" means the owner, operator, lessor, or sublessor of a self-service storage facility, his agent, or any other person authorized to manage the facility or to receive rent from any occupant under a rental agreement.
The owner of a self-service storage facility is not a warehouseman as defined in § 8.7-102, unless the owner issues a warehouse receipt, bill of lading, or other document of title for the personal property stored, in which event, the owner and the occupant are subject to the provisions of Title 8.7 dealing with warehousemen.
3. "Occupant" means a person, his sublessee, successor, or assign, entitled to the use of a leased space at a self-service storage facility under a rental agreement.
4. "Rental agreement" means any agreement or lease that establishes or modifies the terms, conditions, or rules concerning the use and occupancy of a self-service storage facility.
5. "Leased space" means the individual storage space at the self-service facility which is leased or rented to an occupant pursuant to a rental agreement.
6. "Personal property" means movable property, not affixed to land and includes, but is not limited to, goods, wares, merchandise, motor vehicles, and household items and furnishings.
7. "Default" means the failure to perform on time any obligation or duty set forth in the rental agreement or this chapter.
8. "Last known address" means that address provided by the occupant in the rental agreement or the address provided by the occupant in a subsequent written notice of a change of address.
A. The owner shall have a lien on all personal property stored within each leased space for rent, labor, or other charges, and for expenses reasonably incurred in its sale pursuant to this chapter. Such lien shall attach as of the date the personal property is stored within each leased space, and, to the extent the property remains stored within such leased space, as hereinafter provided, shall be superior to any other existing liens or security interests to the extent of $250 or, if the leased space is a climate-controlled facility, $500. In addition, such lien shall extend to the proceeds, if any, remaining after the satisfaction of any perfected liens and the owner may retain possession of such proceeds until the balance, if any, of such charges is paid.
B. In the case of any motor vehicle or watercraft which is subject to a lien, previously recorded on the certificate of title, the owner, so long as the motor vehicle or watercraft remains stored within such leased space, shall have a lien on such vehicle or watercraft as provided for herein to the extent of $250 or $500 if the leased space is a climate-controlled facility. In addition, such lien shall extend to the proceeds, if any, remaining after the satisfaction of any recorded liens and the owner may retain possession of such proceeds until the balance, if any, of such charges is paid.
C. The rental agreement shall contain a statement, in bold type, advising the occupant of the existence of such lien, and that the personal property stored within the leased space may be sold to satisfy the lien if the occupant is in default.
§ 55-419. Enforcement of lien.
A. 1. If any occupant is in default under a rental agreement, the owner shall notify the occupant of such default by regular mail at his last known address. If such default is not cured within ten days after its occurrence, then the owner may proceed to enforce such lien by selling the contents of the occupant's unit at public auction, for cash, and apply the proceeds to satisfaction of the lien, with the surplus, if any, to be disbursed as hereinafter provided. Before conducting such a public auction, the owner shall notify the occupant as prescribed in subsection C of this section and shall advertise the time, place, and terms thereof in such manner as to give publicity thereto.
2. In the case of personal property having a fair market value in excess of $1,000, and against which a creditor has filed a financing statement in the name of the occupant at the State Corporation Commission or in the city or county where the self-service storage facility is located or in the city or county in Virginia shown as the last known address of the occupant, or if such personal property is a motor vehicle or watercraft required by the laws of Virginia to be registered and the Department of Motor Vehicles or Department of Game and Inland Fisheries shows a lien on the certificate of title, the owner shall notify the lienholder of record, by certified mail, at the address on the financing statement or certificate of title, at least 10 days prior thereto of the time and place of the proposed public auction.
If the owner of the personal property cannot be ascertained, the name of "John Doe" shall be substituted in the proceedings hereunder and no written notice shall be required. Whenever a motor vehicle or watercraft is sold hereunder, the Department of Motor Vehicles or Department of Game and Inland Fisheries shall issue a certificate of title and registration to the purchaser thereof upon his application containing the serial or motor number of the vehicle or watercraft purchased, together with an affidavit by the lienholder, or by the person conducting the public auction, evidencing compliance with the provisions hereof.
B. Whenever the occupant is in default, the owner shall have the right to deny the occupant access to the leased space.
5. The name, street address, and telephone number of the owner or his designated agent whom the occupant may contact to respond to the notice.
D. At any time prior to the public auction pursuant to this section, the occupant may pay the amount necessary to satisfy the lien and thereby redeem the personal property.
E. In the event of a public auction pursuant to this section, the owner may satisfy his lien from the proceeds of the public auction, and shall hold the balance, if any, for delivery on demand to the occupant or other lienholder referred to in this chapter. However, the owner shall not be obligated to hold any balance for a lienholder of record notified pursuant to subdivision A 2, or any other lien creditor, that fails to claim an interest in the balance within thirty days of the public auction. So long as the owner complies with the provisions of this chapter, the owner's liability to the occupant under this chapter shall be limited to the net proceeds received from the public auction of any personal property, and as to other lienholders, shall be limited to the net proceeds received from the public auction of any personal property covered by such superior lien.
F. Any public auction of the personal property shall be held at the self-service storage facility or at the nearest suitable place to where the personal property is held or stored. An advertisement shall be published in a newspaper of general circulation in the county, city or town in which the public auction is to be held at least once prior to the public auction. The advertisement must state (i) the fact that it is a public auction; (ii) the date, time and location of the public auction; and (iii) form of payment.
G. A purchaser in good faith of any personal property sold or otherwise disposed of pursuant to this chapter takes such property free and clear of any rights of persons against whom the lien was valid.
H. Any notice made pursuant to this section shall be presumed delivered when it is deposited with the United States Postal Service and properly addressed to the occupant's last known address with postage prepaid.
§ 55-419.1. Other legal remedies may be used.
The provisions of this chapter shall not preempt or limit the owner's use of any additional remedy otherwise allowed by law.
§ 55-420. Care, custody and control of property.
Unless the rental agreement specifically provides otherwise, the exclusive care, custody, and control of all personal property stored in the leased space shall remain vested in the occupant.
All rental agreements, entered into prior to July 1, 1981, which have not been extended or renewed after that date, shall remain valid and may be enforced or terminated in accordance with their terms or as permitted by any other statute or law of this Commonwealth.
§ 55-423. Effective date and application of chapter.
The provisions of this chapter shall apply to all rental agreements entered into or extended or renewed after July 1, 1981.


Left: Control cells exposed to hydrogen peroxide. Right: Cells treated with carnosic acid are protected from hydrogen peroxide. Live cells are stained green, dead cells are stained red.
Herbs widely used throughout history in Asian and early European cultures have received renewed attention by Western medicine in recent years. Scientists are now isolating the active compounds in many medicinal herbs and documenting their antioxidant and anti-inflammatory activities. In a study published in the journal Investigative Ophthalmology & Visual Science, Stuart A. Lipton, M.D., Ph.D. and colleagues at Sanford-Burnham Medical Research Institute report that carnosic acid, a component of the herb rosemary, promotes eye health.
Lipton's team found that carnosic acid protects retinas from degeneration and toxicity in cell culture and in rodent models of light-induced retinal damage. Their findings suggest that carnosic acid may have clinical applications for diseases affecting the outer retina, including age-related macular degeneration, the most common eye disease in the U.S.
Age-related macular degeneration likely has many underlying causes. Yet previous studies suggest that the disease might be slowed or improved by chemicals that fight free radicals—reactive compounds related to oxygen and nitrogen that damage membranes and other cell processes.
Lipton's team first discovered a few years ago that carnosic acid fights off free radical damage in the brain. In their latest study, Lipton and colleagues, including Tayebeh Rezaie, Ph.D. and Takumi Satoh, Ph.D., initially investigated carnosic acid's protective mechanism in laboratory cultures of retinal cells.
The researchers exposed the cells growing in the dish to hydrogen peroxide in order to induce oxidative stress, a factor thought to contribute to disease progression in eye conditions such as macular degeneration and retinitis pigmentosa. They found that cells treated with carnosic acid triggered antioxidant enzyme production in the cells, which in turn lowered levels of reactive oxygen and nitrogen species (cell-damaging free radicals and peroxides).
Lipton, Rezaie, Satoh and colleagues next tested carnosic acid in an animal model of light-induced damage to photoreceptors—the part of the eye that converts light to electrical signals, enabling visual perception. As compared to the untreated group, rodents pre-treated with carnosic acid retained a thicker outer nuclear layer in the eye, indicating that their photoreceptors were protected. The carnosic acid-treated rodents also exhibited better electroretinogram activity, a measure of healthy photoreceptor function.
What's next for carnosic acid? "We're now developing improved derivatives of carnosic acid and related compounds to protect the retina and other brain areas from a number of degenerative conditions, including age-related macular degeneration and various forms of dementia," said Lipton, director of Sanford-Burnham's Del E. Webb Neuroscience, Aging, and Stem Cell Research Center and an active clinical neurologist.


Researchers in Sweden are currently studying how cats communicate with humans, how they respond to the way their humans speak to them and whether or not cats communicate in different dialects.
Do you know what your cat is saying when it meows at you? Researchers in Sweden are trying to give us a better idea by identifying melodic patterns in cat meows: Is your cat hungry or really hungry? Additionally, the way you talk to your cat may influence how your cat talks back.


Super Smash Bros. Wii U and 3DS are rumoured to be getting Kid Icarus character Palutena as a playable character, according to two off-screen photos posted online. The jury's out on them though, so venture within sceptically.
It follows this new Smash Bros. Wii U screen from Masahiro Sakurai, that suggests some form of single-player mode to replace Subspace Emissary.
GoNintendo posted the below photos online, but did not take them. The site notes that the Palutena model seen hasn't been ripped from any existing Nintendo title, and that he background is also new. However, the Mario sprite does look a little out of place next to her.
Could we be about to see another character reveal from Sakurai? Let us know what you think below.


text:
"Мисъл" е българско списание, издавано в София в периода 1892 – 1907 г. След спиране издаването на списанието излизат два сборника "Мисъл" през 1910 г.

Тиражът му варира от 1200 до 2000 броя. Печата се в печатница "Либералний клуб".

История
Първоначално "Мисъл" изразява демократични и реалистични позиции. Постепенно около списанието, дълго след като то се е утвърдило, възниква така нареченият кръг "Мисъл". Кръгът "Мисъл", наречен по името на списанието, включва 4 творци – д-р Кръстев, П. П. Славейков, П. Ю. Тодоров и П. К. Яворов. Повлияни от немската идеалистическа философия и естетика, списанието постепенно внася новите насоки на индивидуализма и естетизма в българската литература и се отдалечава от реалистичното направление. Тематиката на творбите е философска и психологическа, на преден план е изведена личността. Славейков мечтае за литература, която възпява "човека в българина" – като противовес на Вазовата традиция до този момент, която възпява българина.

Външни препратки
 Дигитализирана версия на списание "Мисъл" в проекта "Българският литературен модернизъм"
 За списанието в Знам.bg
 Галин Тиханов, "Жанровото съзнание на кръга "Мисъл" (1998)
 Елка Трайкова, "Как Александър Балабанов чете списание "Мисъл"
 Яница Радева, "Списание "Мисъл" през 1905 г. като възможен проект на Яворов"

Източници

Литературни списания
Спрени списания в София
Основани в България през 1892 година
Пейо Яворов

redpajama_set_name: RedPajamaWikipedia


text:
Q: How to sketch a tree with Expression Blend? I created a WPF steckflow project under Expression Blend 2013.
I would like to sketch a navigation tree to demonstrate how users can select items in a tree. The tree should represent categories at the first level (Cat 1, Cat 2, ...) and items should be under each category node. It should be pretty similar to the navigation tree of the Assets in Blend.
How can I sketch this tree?
Thank you

A: Right so what you're referring to is called a TreeView that you can find and use by going to your "Assets" tab and choosing "Controls" then selecting the TreeView and dragging it to your design surface. Then of course you'll have to add items and sub-items to it.
Hope this helps. Cheers


Leveraged Equities Finance Limited (LEFL) is a specialist margin lending operation that provides finance in NZD and AUD based on your investment portfolio as security. This flexible credit facility enables you to take advantage of any investment opportunities that may arise, such as new issues, rights issues or increasing your exposure to an existing security.
A margin lending facility with Leveraged Equities will allow you to drawdown funds in New Zealand dollars and Australian dollars. This will allow you to participate in both New Zealand and Australian investment opportunities.
Generally interest is charged on a floating basis, however you may elect to draw down some or all of your loan on a fixed rate basis.
Once you have decided what amount and funding period you choose for your fixed rate advance, we will advise you whether we are willing to make the advance, and the interest rate applicable. You must then confirm whether you accept that interest rate.


Fenner & Esler has a earned well-deserved reputation as a top engineers and architects insurance company. We've earned this reputation by giving comprehensive risk-management services through top engineer and architects insurance for more than three decades. The fact that we're an independent insurance brokerage means that we are able to provide architect and engineer at a level that'll suit the size of the business and the scope of their jobs. The E & O Insurance For AE's we are able to offer is extremely economical because of this.
In our current litigious society, an architects and engineers insurance company supplies protection from the economic devastation that may happen even with unfounded claims. Since defending against charges of neglect can cost thousands of dollars, E & O Insurance Coverage For AE's provides architects and engineers the peace of mind that arises from understanding their legal expenses are covered in case of a lawsuit. The policies we offer can be scaled, so you won't ever pay for more coverage than that which you will need.
The importance of obtaining quality coverage from a respected architects and engineers insurance brokerage is something that a lot of people just starting out as design professionals underestimate. Many firms have commercial general liability, or CGL policies and operate under the belief that this is enough. However, this is only a general policy which protects against financial losses which might occur from personal injury or property damage as a result of your services or place of business. Coverage against errors and omissions however is what's essential for architects or engineers specifically. Regardless of how experienced you're, this is still something which could happen to any firm. Without this kind of insurance you'd be forced to cover it out of your own pocket. Even in the event that you're found not at fault if there's a claim of an error or omission made by the client, you may be forced to pay for substantial legal fees. Many own small firms and decide this isn't something which is worth investing in. However, these kinds of lawsuits are capable of devastating many smaller firms, so this is far from the truth. Depend on Fenner & Esler's services as a top engineers and architects insurance company instead.
Additionally, we also offer employment practice liability insurance for A & E. Nearly all design practice firms employ a staff of assistants and secretaries to keep the office running efficiently. It is an unfortunate reality nevertheless that claims of sexual harassment, discrimination, and wrongful termination do arise in even the closest of architecture and engineering firms. To shield your practice from the extraordinary price of litigating and settling these lawsuits, we provide reasonably priced, top quality architects & engineers employment practice liability insurance.
If you should be looking for an insurance company for EPLI for ACEC member firms, AIA members, and NSPE member firms, Fenner & Esler is your best option. Saving you thousands of dollars in premiums, we provide offer insurance policies approved by the AIA, NSPE, and ACEC of the highest quality. Together with our customized risk-management strategies, employment practice insurance for NSPE member firms, ACEC members, and AIA members will give you the security you require to do business and not worry about the future.
Balancing value and coverage is absolutely vital when it comes to working with an engineers and architects insurance brokerage. This is why working with a larger brokerage is not only difficult, but it's not in your best interest. No two firms are exactly the same, but you may find that you're being forced into a one size fits all policy and not receiving individualized attention if you work with a bigger firm. As a leading independent engineers and architects insurance broker however, making certain you are supplied with policies that are flexible and fair is our highest priority. You might find that you're forced into a policy where you're paying extra for coverage that isn't going to be required by your firm considering the work you do if you obtain insurance from a larger brokerage. You may attempt to rectify this situation and find a policy which is more cost-effective, but then you might no longer have all the coverage you need for your firm. If you work with the insurance experts at Fenner & Esler, balancing value and coverage won't be something you're going to have to be worried about. You're able to be confident that your policy isn't going to force you to pay for services you will not require but you'll still have all the coverage you need.
Are you looking for insurance from a leading architects and engineers insurance company? At Fenner & Esler we are dedicated to making it as simple as possible. Do you already have a policy? Having an expert like Fenner & Esler review it and see if we can do better may be a smart idea. Working with us can offer your firm a large number of advantages, including the fact that standards and requirements in your industry are things we are always certain to stay up to date with. You may not be receiving the deal that's right for you taking into account the fact that when it comes to larger on-line architects and engineers insurance companies you seldom get a significant level of individualized service. If you'd like to apply for coverage we make it simple on our website with separate forms for small firms if your billings are less than $1,000,000 and one for big firms if you are over. Do not hesitate to contact us at Fenner & Esler today.
To really receive the best protection for your firm with Errors And Omissions For architects & engineers, it's to your greatest benefit to locate a quality engineer and architect insurance broker possessing considerable experience working with the design sector, such as Fenner & Esler. When you are trying to locate the best AE's E&O company, Fenner & Esler is your best option.


text:
Stock Market OTC Stocks News NASDAQ Biopharmaceutical Cannabis NYSE
Home Stock Market BIIB (Biogen) and IONS (Ionis Pharmaceuticals) Announce Update on SPINRAZA (nusinersen) Phase 3 CHERISH Study (Later-Onset Spinal Muscular Atrophy)
BIIB (Biogen) and IONS (Ionis Pharmaceuticals) Announce Update on SPINRAZA (nusinersen) Phase 3 CHERISH Study (Later-Onset Spinal Muscular Atrophy)
Biogen and Ionis Pharmaceuticals Announce SPINRAZA (nusinersen) Meets Primary Endpoint at Interim Analysis of Phase 3 CHERISH Study in Later-Onset Spinal Muscular Atrophy
via business wire
CAMBRIDGE, Mass. & CARLSBAD, Calif.--(BUSINESS WIRE)--
Biogen (BIIB) and Ionis Pharmaceuticals (IONS) announced that SPINRAZATM (nusinersen), an investigational treatment for spinal muscular atrophy (SMA), met the primary endpoint at the interim analysis of CHERISH, the Phase 3 study evaluating SPINRAZA in later-onset (consistent with Type 2) SMA. The analysis found that children receiving SPINRAZA experienced a highly statistically significant improvement in motor function compared to those who did not receive treatment. SPINRAZA demonstrated a favorable safety profile in the study.
This Smart News Release features multimedia. View the full release here: http://www.businesswire.com/news/home/20161107005392/en/
"These results, along with our successful trial in infantile-onset SMA, reinforce the potential of SPINRAZA to benefit a broad range of SMA patients," said Michael Ehlers, M.D., Ph.D., executive vice president, head of Research and Development at Biogen. "We will make regulators around the globe aware of this data and will continue working closely with them to bring SPINRAZA to families affected by SMA as quickly as possible."
Biogen is preparing for the potential launch of SPINRAZA in the U.S. possibly as early as the end of 2016 or the first quarter of 2017.
Results From the CHERISH Interim Analysis
CHERISH is a fifteen-month study investigating SPINRAZA in 126 non-ambulatory patients with later-onset SMA (consistent with Type 2), including patients with the onset of signs and symptoms at greater than 6 months and an age of 2 to 12 years at screening.
Results from the primary endpoint of the pre-specified interim analysis demonstrated a difference of 5.9 points (p= 0.0000002) at 15 months between the treatment (n=84) and sham-controlled (n=42) study arms, as measured by the Hammersmith Functional Motor Scale Expanded (HFMSE). From baseline to 15 months of treatment, patients who received SPINRAZA achieved a mean improvement of 4.0 points in the HFMSE, while patients who were not on treatment declined by a mean of 1.9 points. The HFMSE is a reliable and validated tool specifically designed to assess motor function in children with SMA, and a change of three points or greater in the HFMSE has previously been identified as clinically meaningful. Data from the other endpoints analyzed were consistently in favor of children who received treatment. SPINRAZA demonstrated a favorable safety profile. The majority of the adverse events were considered to be either related to SMA disease, common events in the general population, or events related to the lumbar puncture procedure. No patients discontinued the study.
With the positive interim analysis, the CHERISH study will be stopped and participants will be able to transition into the SHINE open-label extension study to receive SPINRAZA. Full study results will be presented at future medical congresses.
"These data further validate the potential of SPINRAZA as a treatment for patients with SMA," said B. Lynne Parshall, chief operating officer of Ionis Pharmaceuticals. "We are grateful to all the families and clinicians who have participated in all of the SPINRAZA studies. Without their commitment and support, this program would not have been able to progress so quickly."
The U.S. Food and Drug Administration (FDA) recently accepted the company's New Drug Application (NDA) for SPINRAZA as a treatment for SMA and communicated they plan to act early on the NDA under an expedited review. Additionally, the European Medicines Agency (EMA) recently validated Biogen's Marketing Authorization Application (MAA) in the EU. The EMA's Committee for Medicinal Products for Human Use (CHMP) granted Accelerated Assessment status and the FDA granted Priority Review to SPINRAZA. Biogen is initiating regulatory filings in other countries in the coming months.
Biogen initiated a global expanded access program (EAP) in infantile-onset SMA earlier this year. The company will continue to explore where and when the EAP may be broadened to include patients with later-onset SMA (consistent with Type 2).
The SPINRAZA Clinical Trial Program
SPINRAZA has been studied in both presymptomatic and symptomatic patients with SMA including patients likely to develop or diagnosed with SMA Types 1, 2, and 3.
The SPINRAZA Phase 3 program is comprised of two registrational studies, ENDEAR and CHERISH. ENDEAR is a thirteen-month study investigating SPINRAZA in 122 patients with infantile-onset SMA, including patients with the onset of signs and symptoms of SMA at up to six months of age. The endpoint pre-specified for the interim analysis of the study evaluated the proportion of motor milestone responders from the motor component of the Hammersmith Infant Neurological Examination (HINE). Given the results of the positive interim analysis, the ENDEAR study is being stopped and participants are able to transition into the SHINE open-label study, in which all patients will receive SPINRAZA.
Additionally, the SHINE open-label extension study for patients who previously participated in ENDEAR or CHERISH is open and is intended to evaluate the long-term safety and tolerability of SPINRAZA.
Two additional Phase 2 studies, EMBRACE and NURTURE, were designed to collect additional data on SPINRAZA. EMBRACE is studying a small subset of patients with infantile or later-onset SMA who do not meet the age and other criteria of ENDEAR or CHERISH. NURTURE is an open-label, ongoing study in pre-symptomatic infants who are up to six weeks of age at time of first dose to determine if treatment before symptoms begin would prevent or delay the onset of SMA symptoms. An interim analysis of NURTURE showed that infants treated for up to one year with SPINRAZA achieved motor milestones in timelines more consistent with normal development than what is observed in the natural history of patients with Type 1 SMA. Three infants experienced adverse events considered possibly related to SPINRAZA, all of which resolved. In addition, no infants have discontinued or withdrawn from the study and no new safety concerns have been identified. NURTURE is currently active and enrolling. All studies are being conducted on a global scale.
About SMA1-5
Spinal Muscular Atrophy (SMA) is characterized by loss of motor neurons in the spinal cord and lower brain stem, resulting in severe and progressive muscular atrophy and weakness. Ultimately, individuals with the most severe type of SMA can become paralyzed and have difficulty performing the basic functions of life, like breathing and swallowing.
Due to a loss of, or defect in the SMN1 gene, people with SMA do not produce enough survival motor neuron (SMN) protein, which is critical for the maintenance of motor neurons. The severity of SMA correlates with the amount of SMN protein. People with Type 1 SMA, the most severe life-threatening form, produce very little SMN protein and do not achieve the ability to sit without support or live beyond 2 years without respiratory support. People with Type 2 and Type 3 produce greater amounts of SMN protein and have less severe, but still life-altering forms of SMA.
Currently, there is no approved treatment for SMA.
To support awareness and education in SMA, Biogen has launched Together in SMA in the United States. Together in SMA is a program created to provide informational materials and resources to the SMA community. Learn more at www.TogetherinSMA.com.
About SPINRAZA (nusinersen)
SPINRAZA is an investigational, potentially disease-modifying therapy for the treatment of SMA that was discovered and developed by Ionis Pharmaceuticals, a leader in antisense therapeutics. SPINRAZA is an antisense oligonucleotide (ASO) that is designed to alter the splicing of SMN2, a gene that is nearly identical to SMN1, in order to increase production of fully functional SMN protein.7
ASOs are short synthetic strings of nucleotides designed to selectively bind to target RNA and regulate gene expression. Through use of this technology, SPINRAZA has the potential to increase the amount of functional SMN protein in infants and children with SMA.
Both the U.S. and EU have granted SPINRAZA Orphan Drug status. Additionally, both the U.S. and EU regulatory agencies have granted special status to SPINRAZA, including Fast Track Designation and Priority Review in the U.S. and Accelerated Assessment in the EU.
Biogen exercised its option to worldwide rights to SPINRAZA in August 2016.
Biogen and Ionis Pharmaceuticals acknowledge support from the following organizations for SPINRAZA: Cure SMA, Muscular Dystrophy Association, and SMA Foundation, intellectual property licensed from Cold Spring Harbor Laboratory and the University of Massachusetts Medical School.
About Biogen
Through cutting-edge science and medicine, Biogen discovers, develops and delivers worldwide innovative therapies for people living with serious neurological, autoimmune and rare diseases. Founded in 1978, Biogen is one of the world's oldest independent biotechnology companies and patients worldwide benefit from its leading multiple sclerosis and innovative hemophilia therapies. For more information, please visit www.biogen.com. Follow us on Twitter.
About Ionis Pharmaceuticals Inc.
Ionis is the leading company in RNA-targeted drug discovery and development focused on developing drugs for patients who have the highest unmet medical needs, such as those patients with severe and rare diseases. Using its proprietary antisense technology, Ionis has created a large pipeline of first-in-class or best-in-class drugs, with over a dozen drugs in mid- to late-stage development. Drugs currently in Phase 3 development include volanesorsen, a drug Ionis is developing and plans to commercialize through its wholly owned subsidiary, Akcea Therapeutics, to treat patients with either familial chylomicronemia syndrome or familial partial lipodystrophy; IONIS-TTRRx, a drug Ionis is developing with GSK to treat patients with all forms of TTR amyloidosis; and SPINRAZA (nusinersen), a drug Ionis is developing with Biogen to treat infants and children with spinal muscular atrophy. Ionis' patents provide strong and extensive protection for its drugs and technology. Additional information about Ionis is available at www.ionispharma.com.
Biogen Safe Harbor
This press release contains forward-looking statements, including statements relating to the potential safety and efficacy of SPINRAZA, clinical trial results, potential regulatory approval and the timing thereof, and planning for launch readiness. These statements may be identified by words such as "believe," "except," "may," "plan," "potential," "will" and similar expressions, and are based on our current beliefs and expectations. Drug development and commercialization involve a high degree of risk, and only a small number of research and development programs result in commercialization of a product. Factors which could cause actual results to differ materially from our current expectations include: the risk that unexpected concerns may arise from additional data or analysis from our clinical trials; regulatory submissions may take longer or be more difficult to complete than expected; regulatory authorities may require additional information or further studies or may fail to approve or may delay approval of SPINRAZA or grant marketing approval that is different than anticipated; and risks relating to the potential launch of SPINRAZA, including preparedness of healthcare providers to treat patients, the ability to obtain and maintain adequate reimbursement for SPINRAZA and other unexpected difficulties or hurdles. For more detailed information on the risks and uncertainties associated with our drug development and commercialization activities, please review the Risk Factors section of our most recent annual report or quarterly report filed with the Securities and Exchange Commission. Any forward-looking statements speak only as of the date of this press release and we assume no obligation to update any forward-looking statement.
Ionis Forward-looking Statement
This press release includes forward-looking statements regarding Ionis' strategic relationship with Biogen and the development, activity, therapeutic potential, safety and commercialization of SPINRAZA. Any statement describing Ionis' goals, expectations, financial or other projections, intentions or beliefs is a forward-looking statement and should be considered an at-risk statement. Such statements are subject to certain risks and uncertainties, particularly those inherent in the process of discovering, developing and commercializing drugs that are safe and effective for use as human therapeutics, and in the endeavor of building a business around such drugs. Ionis' forward-looking statements also involve assumptions that, if they never materialize or prove correct, could cause its results to differ materially from those expressed or implied by such forward-looking statements. Although Ionis' forward-looking statements reflect the good faith judgment of its management, these statements are based only on facts and factors currently known by Ionis. As a result, you are cautioned not to rely on these forward-looking statements. These and other risks concerning Ionis' programs are described in additional detail in Ionis' annual report on Form 10-K for the year ended December 31, 2015, and its most recent quarterly report on Form 10-Q, which are on file with the SEC. Copies of these and other documents are available from the Company.
BIOGEN and the BIOGEN logo are registered trademarks of BIOGEN. SPINRAZATM is a trademark of BIOGEN.
Ionis Pharmaceuticals™ is a trademark of Ionis Pharmaceuticals, Inc. Akcea Therapeutics™ is a trademark of Ionis Pharmaceuticals, Inc.
Darras B, Markowitz J, Monani U, De Vivo D. Chapter 8 - Spinal Muscular Atrophies. In: Vivo BTD, ed. Neuromuscular Disorders of Infancy, Childhood, and Adolescence (Second Edition). San Diego: Academic Press; 2015:117-145.
Lefebvre S, Burglen L, Reboullet S, et al. Identification and characterization of a spinal muscular atrophy-determining gene. Cell. 1995;80(1):155-165.
Mailman MD, Heinz JW, Papp AC, et al. Molecular analysis of spinal muscular atrophy and modification of the phenotype by SMN2. Genet Med. 2002;4(1):20-26.
Monani UR, Lorson CL, Parsons DW, et al. A single nucleotide difference that alters splicing patterns distinguishes the SMA gene SMN1 from the copy gene SMN2. Hum Mol Genet. 1999;8(7):1177-1183.
Peeters K, Chamova T, Jordanova A. Clinical and genetic diversity of SMN1-negative proximal spinal muscular atrophies. Brain. 2014;137(Pt 11):2879-2896.
Rigo F, Hua Y, Krainer AR, Bennett CF. Antisense-based therapy for the treatment of spinal muscular atrophy. J Cell Biol. 2012;199(1):21-25
7. Hua Y, Sahashi K, Hung G, Rigo F, Passini MA, Bennett CF, Krainer AR. Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model. Genes Dev. 2010 Aug 1; 24(15):16344-44
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I designed a mobile app to supplement many gamers' needs, which mainly include the ability to track in-game statistics and to easily access game guides and walkthroughs. This app would improve the quality of gamers' user experience because they can manage their game library and progress anywhere they like.
From personal experience and frequent discussions with friends, I realized that some dedicated gamers juggle between multiple games at once and have a growing backlog of games. This frustrates them as new games release during busy times, and the number of games they are interested in playing grow each week.
Before designing the app, I wanted to identify the competitors that already exist in this market. I researched five other products that offer related and similar features for gamers, which allows me to pinpoint the features that my app should include.
Not required, but users can sign in / sign up manually or through Facebook or Google. The account serves no special purpose on the app.
Required to use any features.
Required, but website still can be used without logging in. Users can view the games in their backlog and set playthroughs for specific games.
Required, but website still can be used without logging in. Users can view the games in their backlog and set playthroughs and missions for specific games. There is also a chat feature on user profiles where other users can leave comments.
Required to use any features. Users can create unique profiles and showcase their gaming backlogs.
Required, but website still can be used without logging in.
No need to create an account. Data is saved on the device.
The active IGN community forums are not present in the app.
The app allows users to view and interact with other PlayStation users and their gaming-related statistics.
There is an active forum with members discussing specific video games and giving site feedback. There is also an off-topic section.
There is an active forum with members discussing video games in general, video game collecting, and giving site feedback. There is also an off-topic section.
There is an active forum with members discussing specific video games in their backlog and Grouvee's own gaming podcast. There is also an off-topic section.
However, the app links to a Reddit subreddit for any discussions.
Users cannot browse individual games, but they can browse game news, reviews, and walkthrough created by IGN.
Users can browse games from the PlayStation store (external store), their own game trophies, or other player's trophies.
Users can search through thousands of games from different platforms with different search parameters. Users can also search for their Steam Profile to see how long it would take to beat their game collection.
Users can search through games with search parameters.
Users cannot search through games. They only can manually add their games by typing in the title and choosing the platform.
However, users cannot search with specific search parameters.
Users can search through a collection of games and are able to import their game backlog from their Steam profile, PlayStation 4 account, Xbox One account, and more.
Users can compare their own statistics with their friends, including their game library and trophies. There is also an activity feed of friends' trophy acquisition.
Users can add community users as friends and view users' and friends' stats.
Users can use the Multitap feature to stay updated on friends' progress on games. However, there are no leaderboards.
However, users must manually add friends by first/last names, location. This friends list is primarily used to keep track of game and hardware loans from friends.
However, content is not listed by games. Reviews, news, and game walkthroughs are listed in their own sections, and not specific game information is not listed by individual games.
Users can view information for specific games in the PlayStation store (external website), as well as trophy for each game that they and their friends own.
Each game has an overview that describes what the game is, its developer, publisher, and the length of the game and its DLCs and expansions.
Similar compared to HLTB, plus user's progress can be compared with other users and friends.
Each game is manually added so no information is available except for the game's platform.
Each game has an overview that describes what the game is, its developer, publisher, and users can submit reviews of the game for others to read.
There are advertisements and a subscription plan called IGN Prime that is not prevalent in the mobile app.
There are advertisements in the activity feed. Users can pay for PlayStation subscription service called PS Plus, but it does not add features within the mobile app.
Nowhere to donate, but there is a contact form.
There are banner ads and there is also a Grouvee Gold membership that removes those ads, access to giveaways, and other benefits. $10 a year.
There are ads along with a premium version that removes ads, allow for Dropbox and Google Drive support, and more features.
To design an app that would actually solve these real-world problems that many gamers face, I interviewed 10 individuals who I consider as dedicated gamers. Most of the interviewees are my close connections. The interviews are semi-structured and lasted for about 20 to 30 minutes.
Through analyzing my interview notes, I noticed two distinct categories of interviewees that cover most of the use cases for the app, which I used to create the user personas below.
James is a third-year college student at the University of Michigan majoring in Computer Science. He owns over 200 games on PC, PlayStation 4, and Xbox One and currently has over 130 unfinished games that he plans to complete in the near future. Unfortunately, he has no concrete or efficient plan to do so.
Seeks a more organized way to complete his currently in-progress games on multiple platforms.
Hopes to find a way to easily track completion rate and achievements in each game and use walk-through videos all in one place to complete the games in a shorter amount of time.
Scarlett is a recent graduate of the University of Michigan School of Information. Having secured a well-suited job about 30 minutes from her home, she now has more free time to explore potential pastimes. Her younger brother is an avid gamer, which has peaked her curiosity in video games. She can be unorganized and has a hard time deciding which game to play in her growing game library on PC, PlayStation 4, and Switch.
Based on patterns I noticed in my research, I wireframed out a few ideas using Sketch.
I also created a user flow diagram to understand what I need to include in my application design. Much of the screens changed as I iterated more in the design process and tested my designs.
To build upon the wireframe, I created higher visual-quality mockups.
One of the largest issues with my first round of high fidelity mockups was with having too many unnecessary screens, options, and inconsistent organization that would have been confusing for users.
Based on the feedback I received from other designers, my prototype went through a few more iterations.
After these above designs were created, I quickly realized that there were several (mainly visual design) issues that needed to be fixed. This intuition convinced me to conduct five usability tests to validate my hypothesis.
These tests I conducted each lasted for about 15 minutes and all were in person with users who were NOT frequent gamers.
The left side draggable/swipe-able navigation is confusing to some users and has discoverability issues.
Alternative - hamburger bar is outside of thumb zone.
Second alternative - bottom tab bar - more appropriate.
Text, especially buttons, is hard to read and is cluttered.
No need to have messaging or friends feature.
Other apps exist for that (e.g. Steam, PS App).
No need to show completed games.
After these results, I evaluated the feedback and redesigned once again.
The current visual theme uses a crimson red color to bring the feeling of youth and power into the hands of passionate gamers.
Using Principle, I incorporated some motion designs to increase and usability of the app.
The user explores the home screen and then chooses a game that they have recently played.
The user visits the game guide screen for the game to read more about one of the game's levels.
Following design guidelines is key.
Initially during my first few rounds of design, I did not follow the iOS 12 Design Guidelines when designing. Instead, I created my own style guide, which was admittedly unorganized and therefore resulted in an overall convoluted app design. But as I have learned after designing random mobile apps during my free time, I found that using existing design guidelines makes my job a lot easier and creates higher quality designs.
Sometimes, assumptions have to be made when designing.
Hypothetically, this mobile app would have to earn the approval of many companies, including Microsoft, Sony, and Nintendo, in order to be officially developed and released to market. Access to users' game library and statistics would have to be given to the app. Without this assumption, however, this app would not be possible.
This made me realize that assumptions would sometimes have to made in a design project because many aspects may be uncertain for a period of time, including approval from developers or a project lead for some design decisions.


text:
OUTSIDE POP
Neil Young shares statement on Capitol riots: "Hatred will never find Freedom"
January 11, 2021 Manny Sanchez
Neil Young has shared his thoughts on last week's Trump-incited riots on the U.S. Capitol. "Sadness and compassion hit me last night as I watched fellow Americans telling their stories," Neil writes in a post on his website. He says Donald Trump betrayed the people, "exaggerated and amplified the truth to foment hatred" and that we need "discussion and solutions" and respect, not hate. "I feel empathy for the people who have been so manipulated and had their beliefs used as political weapons," says Neil. "I may be among them."
As for the way authorities reacted to rioters, Neil said, "I was devastated to see the double standard. The way people were treated in the BLM demonstrations recently, compared to the other day. There is no place here for White Supremacy. People need each other to be truly free. Hatred will never find Freedom."
Neil concludes with, "Social media, at the hands of powerful people – influences, amplifying lies and untruths, is crippling our belief system, turning us against one another. We are not enemies. We must find a way home."
Read Neil's whole statement below.
Sadness and compassion hit me last night as I watched fellow Americans telling their stories
A young lady in tears spoke of being maced in the Capital [sic]. She was crying because she had been attacked and all she was doing was trying to have her voice heard in the Revolution. She was one of thousands who have been carrying the feeling of being persecuted for their beliefs, their feeling that American power just didn't care.
This, to me is beyond my own feelings that our president has betrayed the people, exaggerated and amplified the truth to foment hatred. Resentment of the Democratic party among the insurrectionists at the Capitol was rampant. We don't need this hate. We need discussion and solutions. Respect for one another's beliefs. Not hatred.
I was devastated to see the double standard. The way people were treated in the BLM demonstrations recently, compared to the other day. There is no place here for White Supremacy. People need each other to be truly free. Hatred will never find Freedom.
I learned that a some of the people storming the Capitol were police themselves, and gained peaceful entry by showing their badges. I was shocked to see the Confederate flag being waved inside the chamber; the destruction and disrespect. But mostly I felt bad for the people. With Social media, issues are turned to psychological weapons and used to gather hatred in support of one side or the other. This is what Donald J. Trump has as his legacy.
I still have my strong beliefs. That has not changed. But now I feel empathy for the people who have been so manipulated and had their beliefs used as political weapons. I may be among them. I wish internet news was two-sided. Both sides represented on the same programs. Social media, at the hands of powerful people – influences, amplifying lies and untruths, is crippling our belief system, turning us against one another.
We are not enemies. We must find a way home.
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text:
The 2019 season was Petaling Jaya City's 1st season of competitive football, the top division of Malaysian football and in the Malaysia Super League since rebranded in 2019. The season covers the period from 1 February 2019 to 21 July 2019.

Players

Transfers

In
1st leg

2nd leg

Out
1st leg

2nd leg

Loans out
1st leg

2nd leg

Competitions

Malaysia Super League

League table

Results by matchday

Matches
The Malaysian Football League (MFL) announced the fixtures for the 2019 season on 22 December 2018.

Malaysia FA Cup

Malaysia Cup

Group stage

Friendlies

Squad statistics

Appearances and goals

|-
! colspan=14 style=background:#dcdcdc; text-align:center| Goalkeepers

|-
! colspan=14 style=background:#dcdcdc; text-align:center| Defenders

|-
! colspan=14 style=background:#dcdcdc; text-align:center| Midfielders

|-
! colspan=14 style=background:#dcdcdc; text-align:center| Forwards

|-
! colspan=14 style=background:#dcdcdc; text-align:center| Players away from the club on loan or left the club

Disciplinary record

References

Petaling Jaya City FC
Petaling Jaya City FC seasons
Petaling Jaya City


text:
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Plainview Old Bethpage Herald
Home Sports Old Time Base Ball In Old Bethpage
Old Time Base Ball In Old Bethpage
By Christopher Birsner -
A base ball team at Old Bethpage Village Restoration in classic uniforms and holding unique equipment that fits the time period. (Photos courtesy of Tom Fesolowich)
If you are looking to enjoy local sports during the summer, look no further than Old Bethpage Village Restoration's own Old Time Base Ball league.
Starting in 1979 as a Civil War reenactment, it has since evolved into a recreation of the 1864 base ball (as it was spelled back then) league made up of teams that existed on the island back in that time period, such as the Manetto Hill Surprise of Plainview. Players dress up in vintage uniforms and participate in the sport following the rules and customs of the 19th century game. While it started at Old Bethpage, there are now more than 300 teams across the U.S. and Canada that participate in similar leagues like this.
"We researched and found all mentions of the teams and recreated them," said Thomas Fesolowich, who runs the program. "Those who come will get to learn how the rules are different from modern baseball. They'll be thrown back to a more simple time."
Among the noticeable differences is the fact that the players do not use gloves and use a differently-stitched baseball. When the ball is in play, players must throw the ball underhand. Among the biggest in-game differences is that batters can be declared out if the ball is caught after the first bounce.
"It's baseball, but there are a few rule tweaks," said Fesolowich. "The players are constantly answering questions so that people can get it. There are certain things as a modern baseball player you have to unlearn, such as not overrunning first base. You grow up in little league always learning to overrun first base, but you aren't allowed."
Patrons who visit Old Bethpage the day of a base ball game can actually play that day if they want to. The program is made up entirely of volunteers, those who have a little ability but mostly have an interest in the history of the game.
"Some players do join in the middle of the year, so we take them aside and go over the rules with them," said Fesolowich. "Sometimes its learning by fire. You're thrown into the game and you have to learn these rules as you go."
Old Time Base Ball is held almost every Sunday during the summer. They also run a kids game after each main event called "Rounders," which gives kids a chance to play the game with a softer ball and slightly different rules.
On Aug. 3, Old Bethpage Village Restoration will be holding an event called the "Doc Adams Old Time Base Ball Festival," where teams from across the country come to play various different versions of old-time base ball from the 1850s to 1890s. For more information on the event schedule and all base ball events at the park, visit www.obvrnassau.com.
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Christopher Birsner is a reporter with Anton Media Group.
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text:
Le docteur Frederick Carl Bock Jr., né le  dans le Michigan et mort le  à Scottsdale, est un scientifique américain et un pilote de l'US Air Force durant la Seconde Guerre mondiale. Il participa au raid atomique contre Nagasaki le  avec le B-29 The Great Artiste.

Biographie
Né en 1918 à Greenville dans le Michigan, Frederick Bock est diplômé de l'Université de Chicago en 1939. À la déclaration de guerre, il entre dans l'US Air Force pour devenir pilote sur le front asiatique. Il mène des missions dans l'Himalaya et contre le Japon depuis la Chine.

Sélectionné par Paul Tibbets alors qu'il fait partie du  de B-29, il est incorporé à la partie militaire du projet Manhattan en . Sous le grade de capitaine, il pilote le B-29 d'observation The Great Artiste durant la mission de bombardement atomique sur Nagasaki. Le bombardier qu'il pilotait normalement, Bockscar (la voiture de Bock), avait à son bord l'équipage de Charles Sweeney. Bockscar transporta depuis Tinian la bombe Fat Man qui fut larguée sur la ville japonaise le .

Devenu major et décoré de la Distinguished Flying Cross, il retourna à Chicago pour poursuivre ses études en zoologie. Spécialisé dans la génétique et les statistiques, il développa des algorithmes pour la résolution de problèmes complexes dans divers instituts de recherche de l'Illinois. Il fut ensuite chercheur aux laboratoires Baxter Travenol et prit sa retraite en 1986.

Frederick Bock meurt en 2000 à Scottsdale, en Arizona, des suites d'un cancer.

Liens externes

  Photo de l'équipage du B-29 de Frederick Bock

Aviateur des United States Army Air Forces de la Seconde Guerre mondiale
Naissance dans le comté de Montcalm
Naissance en janvier 1918
Décès dans le comté de Maricopa
Décès en août 2000
Décès à 82 ans
Mort d'un cancer aux États-Unis


text:
Published in Mobiles
Apple set to abandon iPhone X
by Nick Farrell on22 January 2018
Will be quietly offed in Summer
It appears that Apple is starting to doubt that its policy of charging its users double for a product which was pretty much the same as an earlier model has proved to be a disaster and it is set to walk away from the iPhone X.
That is the news from the analyst Ming-Chi Kuo, who normally has a good feel for the doings of Apple. He recently issued a new investor note claiming that Apple's 2018 lineup will feature two brand new versions of the iPhone.
One model is said to feature a 6.5-inch OLED display while the second will reportedly boast a 6.1-inch LCD display. Naturally, both devices will feature edge to edge displays and will use Face ID for user authentication as opposed to Touch ID.
However, he warned that Apple might opt to discontinue the current iPhone X entirely if sales remain underwhelming. In fact he is pretty sure that the iPhone X will be 'end of life' in the summer of 2018, instead of being retained as a lower-cost option in the following year.
If Kuo's projection pans out, this will represent a marked shift in Apple's iPhone sales strategy. Going back nearly a decade, Apple has always positioned older iPhone models around as a wallet-friendly alternative for users who weren't keen on paying a premium for Apple's flagship. This means that the 6.1-inch iPhone with an edgeless LCD will become the more affordable version of the current iPhone X. However, it looks like this will not be the case.
The iPhone 8 and iPhone 8 Plus will stick around for at least another generation too.
Last modified on 22 January 2018
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A full–service custom picture framing and art supply store located in Doylestown, Bucks County, PA. Staffed by helpful, knowledgeable artists ready to help you find the right material for your next creation!
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Braden Unthank took the loss for Eldorado in its season opener Wednesday at Carterville. Unthank allowed eight hits over 3.2 innings, striking out two and walking three.
Eldorado stranded six runners on base and was outhit 9-5 in a 7-0 loss to Carterville to open up its season Wednesday on the road.
Braden Unthank (0-1) worked 3.2 innings, allowing seven runs on eight hits, while striking out two and walking three. Dalton White came on in relief of Unthank and gave up one hit, while striking out one in 2.1 innings.
At the plate, Bryant Byrd and White each paced the Eagles with multiple hit days. White was 2-for-3, while Byrd was 2-for-2. Joe Mayberry had the other hit.
Eldorado is scheduled to return to action Saturday as they travel to Mt. Carmel for a 12:30 p.m. game.


It's used by 3 million people and is probably one of the most cost-effective ways to work around London.
A travelcard is one viable option for traversing the city: it's a one-time payment paper card that lets you travel anywhere in London for the entire day. They're valid on tubes, DLRs, London Overgrond trains, National Rail services, buses or trams. Simply put the card into the reader slot at stations or show the card upon request.
Bear in mind that travelcards are not valid on riverboat services; you'll need to purchase a separate ticket for those, but they're definitely worth the extra cost. Some riverboat tour services will even offer a 1/3 discount if you have a travelcard.
Oyster cards and contactless payment cards are the preferred tools of navigation for most Londoners. For visitors and tourists there are also Visitor Oyster cards, which can be used in exactly the same way but boast a host of special offers.
All you have to do is touch your Oyster/Contactless card on the yellow card reader at station gates when you enter and leave a station, and the fare will be automatically calculated for you.
For the purposes of staying safe, it's best to plan your trip in London before you leave to embark. Though London is one of the safest metropolitan areas in the world of its size, it's still worth being cautious in certain ways.
If you need a taxi or minicab, it's important to opt for an officially registered one. Don't be afraid to enquire about this when you board – it's the driver's responsibility to ensure your safety.
Generally, try to avoid walking by yourself at night, and stick to roads that are well-lit and offer good visibility. Cross roads safely by designated crossings, and only cross when the green man appears on the indicator across the road. Check the ground in front of you for 'Look Left/Look Right' markings, which should indicate which direction traffic is coming from.
In terms of the personal property you're carrying, it's best to keep it out of sight or safely under your table when you're not engaged with it. Many venues even offer clips underneath the tables, so make sure you secure your bags to these when possible. Otherwise keep these close to you and don't opt on carrying too much cash with you at once. Common sense solutions include not accepting drinks from strangers, and keeping track of your belongings at all times.
Dial '101' for your nearest Police service in the unfortunate case that you do lose something.
Don't miss out on one of London's greatest assets: its claim to royalty. There are plenty of royal venues to explore and a long lineage of exciting British history to uncover. Visit Buckingham Palace, home of the Queen in London, and take a look around Hampton Court Palace, Henry VIII's residence of preference. Make sure you catch the Changing the Guard ceremony – senior members of the royal family do!
To get the most from your time in London, it's optimal to plan your journey ahead, and allocate the amount of time you'll be spending and where you'll be spending it. There are plenty of attractions all over the city, but the most prominent you'll find in Central or Zone 1.
Check out the Science Museum, Victoria and Albert Museum, National Galleries, Buckingham Palace, British Museum, Natural History Museum, Greenwich Park, and make sure you don't miss Big Ben!
Oxford Street is undisputed king of shops, if it's big chains you're looking for. You can find just about any well-known high street brand here from River Island to John Lewis. For those with more eclectic tastes, it might be a good idea to explore Camden, situation in North Central London, or Shoreditch; also chock-full of smaller shops. Many of these are fantastic gems – perfect for vintage clothes and less obtrusive consumer marques.
Make sure you complete your stay in lodgings that are comfortable and stylish. Try the Montcalm London City Suites, for instance, for one of the best luxury suites in London.
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Data is being generated all the times by almost everything we do. This data is Big Data and businesses need an innovative way to transform the volume, variety, velocity & complexity of Big Data into a corporate asset. To thrive in disrupt markets we combine business use cases with big data technology solutions for complex data management.
With expertise and capabilities extending towards diverse big data analytics tools and technologies, integrating a modern technology into your existing infrastructure or establishing an entirely new platform is effortless. Ensure enhanced operations, performance, security and reliability as you scale your systems in the data centers, in the cloud or the Internet-of-Things (IoT).
Our solutions enable a customer-focused scenario where organizations can aggregate the information about customer insights, driving behaviors, and plan product improvements.


To join this fast pace industry you really need to have an open mind, you need to be able to adapt very quickly with the way things change in this industry.
Charmayne Chung has blossomed into a confident woman who is able to express her opinions and visions thanks to the creative and diverse community that is Limkokwing.
I think studying in Limkokwing definitely changed my life on a personal level; with it being such a diverse university I get to work with so many different creative people from different walks of life so I think it's built my confidence.
A stroke of luck found Charmayne at a University which offered all that she wanted and lead to an exciting boost into the industry.
Being the Assistant Manager of a huge company doesn't allow Charmayne much time to kick back and relax. But this doesn't mean she's not happy and satisfied with her success so far! She measures success as to how passionate you are about your job, and her greatest achievements happen on a daily basis.
I can't say I have one greatest achievement. Every day is a great achievement, being in this industry it's always changing so every day I'm learning something new.
As far as positive thinking goes Charmayne is right up front. She believes there is no such thing as failure; you only go through a trial and error phase before you find your groove.


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Q: Add or remove field based on select option in Angularjs I am trying to display or hide a field based on the drop-down option selected. Also if the field is active, then the option shouldn't be displayed in the Add filter dropdown list.
I've created a plunker here.
Based on what I have done so far, if I click on the remove field button(x), the field is hidden but when I add the field from the add filter option and try removing it again, it doesn't work.
I'm not sure I'm doing this right and I feel there should be a much better approach to achieving this.
Can anyone be of assistance, please?
Controller
angular.module('app', [])
.controller('Main', ['$scope', function($scope) {

$scope.title = "hello";
$scope.isName = true;
$scope.isDropdown = true;

$scope.hideName = function() {
  $scope.isName = false;
  $scope.removeFilterOption($scope.isName);
};

$scope.hideDropdown = function() {
  $scope.isDropdown = false;
};

$scope.removeFilterOption = function(value) {
  if (value != $scope.isName) {
    $scope.add_options.splice(1, 1);
  } else {
    $scope.add_options.splice(1, 0, {
      text: "Name",
      value: "name"
    });
  }
};

$scope.add_options = [];
$scope.add_filter = $scope.add_options[0];

$scope.selected = function(value) {
  if (value === "name") {
    $scope.isName = true;
  } else if (value === "cars") {
    $scope.isDropdown = true;
  }
}

}]);

Template

{{title}}

   Name

    <button ng-click="hideName()">×</button>

   <input/>

  Cars

    <button ng-click="hideDropdown()">×</button>

  <select>
    <option value="volvo">Volvo</option>
    <option value="saab">Saab</option>
    <option value="mercedes">Mercedes</option>
    <option value="audi">Audi</option>
  </select>

Add filter

  <select
    ng-model="add_filter" ng-selected="selected(add_filter.value)"
    ng-options="x.text for x in add_options track by x.value">
  </select>

A: This can be really simple to do if you remove the tracking. You can do it with simply thinking about ng-show and ng-hide. Check out the code below. You essentially just use ng-show and ng-hide correctly. This sample is a lot more simpler to follow than other approaches. You just have to remember to show hide things in the correct places.

angular.module('app', [])
.controller('Main', ['$scope', function($scope) {

   $scope.title= "hello";
   $scope.isName = true;
   $scope.isCar = true;

   $scope.hideName = function() {
      $scope.isName = false;
    };

    $scope.hideCar = function() {
      $scope.isCar = false;
    };

    $scope.getOption = function() {
      var selected = $scope.selected;
      switch(selected) {
        case "Name":
          $scope.isName = true;
          break;
        case "Cars":
          $scope.isCar = true;
          break;
      }
      $scope.selected = ""; // Reset Drop down
    }

}]);
<!DOCTYPE html>

 <link rel="stylesheet" href="style.css" />

  {{title}}

     Name

        <button ng-click="hideName()">×</button>

      <input/>

     Cars

        <button ng-click="hideCar()">×</button>

      <select>
        <option value="volvo">Volvo</option>
        <option value="saab">Saab</option>
        <option value="mercedes">Mercedes</option>
        <option value="audi">Audi</option>
      </select>

Add filter

  <select ng-model="selected" ng-change="getOption()">
    <option value=""> </option>
    <option ng-hide="isName" value="Name">Name</option>
    <option ng-hide="isCar" value="Cars">Cars</option>
  </select>

A: [Updated] I have changed your functions a little bit and its working fine now . You should not use Splice method like this in your case as you have used , it will just keep on adding names or Cars whenever you add cross button :
PFB the changed code :
$scope.hideName = function() {
  $scope.isName = false;
  $scope.removeFilterOption($scope.isName,"name","Name");
};

$scope.hideDropdown = function() {
  $scope.isDropdown = false;
  $scope.removeFilterOption($scope.isName,"car","Cars");
};

$scope.removeFilterOption = function(value,type,text){
  if($scope.add_options.length>0){
  for(var i=0;i<$scope.add_options.length;i++){
    if(type=='name'){
     $scope.add_options.splice(i,1,{
      text: "Name",
      value: "name"
    });

    }else{
      $scope.add_options.splice(i,1,{
      text: "Cars",
      value: "car"
    });
    }
   }
  }else{
    $scope.add_options.push({
      text:  text,
      value: type
    });

  }

};

This is working fine for me.

A: There are many better ways to approach this, like instead of having 'isName' and 'isDropDown', use something like a filter and assign value to 'name' and dropdown.