A partial shutdown of the US federal government was postponed by a deal struck late Friday night between White House and congressional negotiators to resolve a protracted standoff on legislation to finance government operations.
The Obama administration agreed to $2 billion more in social spending cuts in return for an agreement by the Republican House leadership on a stop-gap continuing resolution that will fund the federal government through next Thursday. President Obama, House Speaker John Boehner and Senate Majority Leader Harry Reid also said they had reached a broader agreement to fund government operations through the end of the fiscal year, September 30, which is to be voted on by both houses of Congress next week.
The deal reportedly includes between $39 billion and $40 billion in social spending cuts in the current fiscal year budget, virtually the total amount demanded by Boehner. This is the largest-ever single-year reduction in domestic social spending.
Details are not yet available of exactly which programs will feel the brunt of the budget axe, but the cuts dwarf any previous austerity exercise. The cuts are four times those imposed by a Republican Congress in 1995-96, the only previous instance of a budget dispute forcing a partial shutdown of the federal government.
Nearly one million federal workers had been given notice of layoff at their workplaces Friday, about half the total workforce. The shutdown would have affected the majority of civilian government workers, but US military and police forces, the intelligence agencies and the Department of Homeland Security were exempted and told to continue normal operations.
The driving force of the budget crisis has been the Republican-controlled House of Representatives, which demanded even greater cuts in current spending than the record $38 billion offered by the Obama administration. Many in the ultra-right Tea Party caucus regarded a shutdown of all non-military parts of the government as a positive good, while Christian fundamentalists demanded further restrictions on abortion rights as the price of passing a budget.
The final hours of negotiations reportedly focused on the continuation of $333 million in federal funding for women's health services provided by Planned Parenthood, which operates 800 health centers throughout the United States, the majority of them serving women in working class and low-income neighborhoods.
None of this federal funding supports abortion services. It pays for services like breast cancer screening, pap smears, pregnancy counseling and contraception. But the fanatical anti-abortion wing of the Republican Party targeted Planned Parenthood because it is the largest provider of abortion services in the United States and a defender of the right of women to have access to abortion.
The Republican leadership reportedly agreed to drop the defunding of Planned Parenthood in the final deal with the White House, and House Republicans voted Friday night to accept the agreement.
However, the Obama administration and Senator Reid agreed to include a provision demanded by the Republicans that bans the District of Columbia from using its own funds to pay for abortion procedures. Under the notorious Hyde Amendment, enacted in the 1970s and never seriously challenged by the Democrats, federal government funds cannot be used to pay for abortions. But the District of Columbia, like many states, uses funds raised from its own tax revenues to do so. This has become a political football because Congress controls District spending. A Republican-controlled Congress barred the practice, and the Democratic-controlled Congress lifted the ban in 2009.
As is invariably the case in such political confrontations in recent US history, the Democratic Party cowers before the demands of the ultra-right and ultimately offers agreements on their terms. Both President Obama and Senate Democratic Leader Harry Reid acceded again and again to additional demands from the House Republicans.
Speaker John Boehner reportedly reached agreement with Reid and Obama last week on $33 billion in cuts in fiscal year 2011 domestic social spending. He had reason to be pleased, since the original demand of the House Republican leadership, put forward in January, was for $32 billion in cuts.
Under pressure from the right wing of the Republican caucus, Boehner raised the figure in spending cuts to $61 billion, incorporated in the budget passed by the House in February. Obama and the Senate Democrats countered with an offer of $10 billion, and the horse-trading continued, while Boehner used the demands for policy changes—on abortion, environmental regulation, and a ban on implementation of the Obama health care program—to extract more and more spending cuts.
Boehner repudiated the $33 billion figure, proposing instead $40 billion in cuts and reportedly getting a counter-offer of $38 billion in cuts from Reid and Obama on Thursday night. But even this new level of austerity proved insufficient.
Some of the most right-wing figures in the Republican Party joined the debate in the final hours, urging Boehner and the House majority to pocket the many concessions from the Democrats without taking the risk of provoking a public backlash against a shutdown of federal services.
Former Arkansas Governor Mike Huckabee, a presidential candidate in 2008 and a potential candidate in 2012, said the Republicans had the "most to lose" in a shutdown, particularly if they alienated rank-and-file military personnel who would be compelled to work but would go without pay until Congress approved a budget.


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Argentina launches lawsuit against Falklands oil drillers
Argentina announced on Friday it had started legal proceedings in one of its own courts against five companies, including three British, who are drilling for oil and gas off the Falkland Islands, a move Britain denounced as bullying.
Britain defeated Argentina in a 1982 war over the South Atlantic islands and administers them as an overseas territory, whose population of around 3,000 voted overwhelmingly to remain under British rule in a referendum in 2013.
Argentina says it is the rightful owner of the islands, which it calls Las Malvinas, a claim dating back centuries to the Spanish colonial era. The dispute has escalated in recent years with the discovery of oil and gas deposits.
"All exploration and exploitation of hydrocarbons on the Argentine continental shelf without Argentine authorisation is illegal," Argentina's government minister responsible for the islands, Daniel Filmus, told Reuters. He said a judge in Rio Grande, Argentina, would take on the case.
British foreign minister Philip Hammond told Sky News television: "Argentina needs to stop this kind of behaviour and start acting like a responsible member of the international community."
The companies targeted in the case are Premier Oil, Falkland Oil and Gas and Rockhopper, listed in Britain, Italy's Edison and Noble Energy which is listed in the United States. The British and Italian firms declined to comment.
Noble Energy said their concessions were off the Falklands Islands, and that their concession contracts were with the Falklands Islands Government.
Filmus said the Argentine court could impose prison terms of as much as 15 years and steep fines against executives of the firms if they were found to have illegally extracted oil and gas.
Earlier this month, Premier Oil and Falkland Oil and Gas kickstarted their 2015 drilling campaign by announcing they had found oil and gas at the first well in a nine-month programme.
In response, Argentina said it would consider legal proceedings against the energy firms. Britain and Argentina summoned each other's ambassadors for a dressing down.
The Falkland Islands government, which administers the islands' domestic affairs while London controls their defence and foreign policy, said it had a right to develop its own economy.
"Exploration drilling has been happening in Falkland Islands waters for many years," it said. "The Government of Argentina continues to ignore our inalienable right to determine our own future."
The 1982 war killed more than 600 Argentine and 255 British soldiers. Defeat led to the downfall of Argentina's military ruler Leopoldo Galtieri, while victory boosted the fortunes of Britain's Prime Minister Margaret Thatcher.
Shares in Premier Oil were trading 1.8 % lower at 1523 GMT on Friday, while Rockhopper shares were up 1.5 % and Falklands Oil and Gas shares traded 3.5 % higher. – Reuters

redpajama_set_name: RedPajamaCommonCrawl


Pyramid International and The Art Group have an in-house team of eight designers based at their Leicester studio.
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The studio handles every aspect of the product design process, from the initial creative concepts to print-ready or production files. It is also integral at every level of Pyramid's operations — from product design and point-of-sale displays, to corporate ID, catalogues, advertising and all approvals.
The Company holds more than 250 active licences, plus many other agreements with artists and rights-holders. Together, these cover a variety of product ranges and international territories.
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in Latest World News
Photos of 9/11 remembrances in the U.S. and around the world
The were no clouds in New York's sky on Saturday. Nearly the same blank blue as the morning of 9/11.
Twenty years on, against a backdrop of extraordinary political divisiveness, Americans this weekend marked the deadliest terrorist strike on U.S. soil with the austere tolling of bells, the soaring strains of "Amazing Grace" and the somber recitation of names of the dead.
The landmark anniversary prompted an outpouring of grief for the nearly 3,000 people killed Sept. 11, 2001, when four hijacked U.S. passenger planes were wielded — unfathomably, still — as weapons.
Family members grieve at the National September 11 Memorial & Museum on Saturday after the ceremony marking the 20th anniversary of the 9/11 attacks.
(Ed Jones/AFP via Getty Images)
The plane crashes at the World Trade Center; Shanksville, Pa.; and the Pentagon galvanized an outpouring of unity and solidarity in the United States. But two decades later, the anniversary showcased myriad ways in which the nation remains wounded, in large part from within, even as it celebrated heroism and resilience.
In groups big and small, Americans and people abroad filed quietly in by the thousands to the National September 11 Memorial & Museum in New York, the Pentagon, the September 11 Memorial Garden in London, and a monument in Rome.
U.S. service members attend the Pentagon 9/11 observance ceremony at the National 9/11 Pentagon Memorial in Arlington, Va.
(Win McNamee/Getty Images)
Former President Clinton, left, former First Lady Hillary Clinton, former President Obama, former First Lady Michelle Obama, President Biden, First Lady Jill Biden, former New York City Mayor Michael Bloomberg, Bloomberg's partner, Diana Taylor, Speaker of the House Nancy Pelosi and Senate Minority Leader Charles E. Schumer stand for the national anthem Saturday in New York City.
(Chip Somodevilla/AFP via Getty Images)
People across the globe sang out songs of American patriotism.
Flags encircling the Washington Monument are flown at half-staff on Saturday in Washington, D.C.
(Anna Moneymaker/Getty Images)
People embrace at the September 11 Memorial Garden at Grosvenor Square on Saturday in London. People across the U.K. paid their respects to the victims of the 9/11 terror attacks.
(Hollie Adams/Getty Images)
The FDNY Pipes and Drums marches past invited guests and families during the FDNY Memorial Service at St. Patrick's Cathedral on Saturday in New York City.
(Alexi Rosenfeld/Getty Images)
343 American flags, representing firefighters who were killed on 9/11, were held during a processional along Fifth Avenue.
A National Park Service ranger stands in front of the Wall of Names at the Flight 93 National Memorial in Shanksville, Pa., before a Service of Remembrance on Saturday.
(Gene J. Puskar/AP)
Roses are placed in the name of Frank Spinelli during a ceremony at the National September 11 Memorial & Museum.
(Anthony Behara/AFP via Getty Images)
Thousands of New Yorkers and visitors placed flowers, photographs and personal belongings on the names engraved into the National September 11 Memorial & Museum.
Two marble columns, which represent the twin towers of the World Trade Center, are seen during a ceremony Saturday in Rome to remember the lives lost.
(Stefano Montesi/Corbis via Getty Images)
Flowers are left next to a picture at the National 9/11 Pentagon Memorial during a wreath-laying ceremony Saturday at the Pentagon.
(Brendan Smialowski/AFP via Getty Images)
Light bounces off of nearby buildings to light the edge of the north pool Saturday at the National September 11 Memorial & Museum in New York City.
Firefighters gather in lower Manhattan near ground zero in New York as the city commemorates the 20th anniversary of the 9/11 terrorist attacks.
(Spencer Platt/Getty Images)
An American flag is unfurled at the Pentagon in Washington, D.C., on Saturday at sunrise.
(J. Scott Applewhite/AP)
As the day began, an American flag was draped over the site of impact at the Pentagon.
A person pays their respects Saturday at the September 11 Memorial Garden at Grosvenor Square in London.
President Biden and First Lady Jill Biden attend a wreath-laying ceremony Saturday at the Flight 93 National Memorial in Shanksville, Pa.
(Jeff Swensen/Getty Images)
The new One World Trade Center tower stands above other skyscrapers Saturday during the commemoration of the 20th anniversary of the 9/11 attacks.
Photo editing by Jacob Moscovitch.
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What's New NetflixMay 2022Den of Thieves
Den of Thieves: Release Date on Netflix
Den of Thieves came out in January (2018) but will it come to Netflix?
Here is everything you need to know about Den of Thieves release date on Netflix (USA). Details include the date it was added to Netflix, the ratings, cast, the plot, and more. Scroll down for more information.
Den of Thieves is a action movie directed by Christian Gudegast. The film was first released on January 19, 2018, and has a 7 rating on IMDb.
Den of Thieves is coming out on Netflix on May 1, 2022. Let's look at the cast, movie plot, reviews, and what's new on Netflix. ⬇
Den of Thieves
Christian Gudegast
Den of Thieves is came out coming out on Netflix on Sunday, May 1, 2022. We use publicly available data and resources such as NetflixSchedule and NetflixDates to ensure that our release date information is accurate. Some Netflix titles are considered original in one country but not in another and may not be available in your region. Additionally, dates may change, so check back frequently as we update this page.
January 19, 2018 (US)
You can start watching Den of Thieves at 3:01 AM ET (Eastern) on the east coast and 1:01 AM PT (Pacific) if you're on the west coast. And, 3:01 AM CT (Central), 2:01 AM MST (Mountain).
An elite unit of the LA County Sheriff's Dept. and the state's most successful bank robbery crew clash as the outlaws plan a seemingly impossible heist on the Federal Reserve Bank.
Den of Thieves is starring Gerard Butler, Pablo Schreiber, O'Shea Jackson Jr..
IMDb: Den of Thieves has an IMDb rating of 7/10 based on 108,482 user votes.
Rotten Tomatoes: Rotten Tomatoes gave Den of Thieves a 88% score.
Please note, these reviews are only accurate at the time of writing. Den of Thieves reviews will be updated regularly.
Den of Thieves is rated: R. An R-rating is a caution by the Rating Board to parents as some content contains some adult material, and may include adult themes, strong language, violence, nudity, drug abuse or other elements. Parents are strongly urged to find out more about this film before they let their children under 17 attend.
Watch Den of Thieves on:
Who is the director of Den of Thieves?
Den of Thieves was produced by Atmosphere Entertainment MM, Diamond Film Productions, G-BASE, and Tucker Tooley Entertainment, with a budget of $30 million. Its initial release on January 19, 2018, made approximately at the Box Office.
Where you can stream Den of Thieves?
You can stream Den of Thieves on Amazon Video or Netflix. Visit Den of Thieves official website for more details.
Is Den of Thieves a Netflix Original?
Den of Thieves is a movie released in 2018.
When did Den of Thieves come out?
Den of Thieves was originally released on Friday, January 19, 2018. The film has been released approximately 4 years, 11 months, and 26 days ago.
Below are interesting links related to Den of Thieves:
– See what's new on Netflix May 2022.
– Find out what movies and shows came out on May 1st.
– Everything you should know about May 1, 2022.


We're excited to announce our next Neo Insights CxO Roundtable on Unlocking Funds for Innovation by Lowering Run Costs in association with Kirkland & Ellis LLP and True Value. This event will be held in Chicago on May 24, 2016 from 2:30 to 5:30pm CDT with a cocktail reception from 5:30pm to 7:00pm CDT.
Join us for a peer discussion on how to successfully execute your run cost reduction plans, how to fund innovation and how to overcome the related talent challenges. All attendees are encouraged to participate in and contribute to the dialogue.
This invitation-only event will provide an intimate, small-group setting for corporate leaders of technology and sourcing to meet and learn from one another through organic conversations.


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Stanford/Yale Study Gives Insight into Subtle Genomic Differences Among Our Own Cells
Stanford University School of Medicine scientists have demonstrated, in a study conducted jointly with researchers at Yale University, that induced-pluripotent stem cells (iPS cells) — the embryonic-stem-cell lookalikes whose discovery a few years ago won this year's Nobel Prize in medicine — are not as genetically unstable as was thought. The new study, which was published online on Novenber 18, 2012 in Nature, showed that what seemed to be changes in iPS cells' genetic makeup — presumed to be inflicted either in the course of their generation from adult cells or during their propagation and maintenance in laboratory culture dishes — instead are often accurate reflections of existing but previously undetected genetic variations among the cells comprising our bodies. That's good news for researchers hoping to use the cells to study disease or, someday, for regenerative medicine. But it raises the question of whether and to what extent we humans are really walking mosaics whose constituent cells differ genetically from one to the next in possibly significant respects, said Alexander Urban, Ph.D., assistant professor of psychiatry and behavioral sciences at Stanford. Dr. Urban shared senior authorship of the study with bioinformatics professor Mark Gerstein, Ph.D., and neurobiology professor Flora Vaccarino, M.D., both of Yale. It's only a few years ago that human iPS cells started becoming available to researchers. These cells hold great promise because they act almost exactly like embryonic stem cells, which can be nudged to differentiate into virtually any of the body's roughly 200 different cell types. But iPS cells can be derived easily from a person's skin, alleviating numerous ethical concerns arising from the necessity of obtaining embryonic stem cells from fertilized eggs.
Variants of TREM2 Gene Nearly Triple Risk of Alzheimer's
A gene so powerful it nearly triples the risk of Alzheimer's disease has been discovered by an international team including researchers from the Mayo Clinic. It is the most potent genetic risk factor for Alzheimer's identified in the past 20 years. The findings were reported November 14, 2012 in the online edition of the New England Journal of Medicine. The team included researchers from 44 institutions around the world, including 10 from the Mayo Clinic's campuses in Florida and Minnesota. The study was led by John Hardy, Ph.D., a researcher at the Institute of Neurology at University College London and a former professor at Mayo Clinic in Florida. The researchers used new sequencing techniques to home in on the TREM2 gene. Additional TREM2 sequencing was then performed, in part, by scientist Dr. Aleksandra Wojtas in the Mayo Clinic in Florida laboratory of Rosa Rademaker, Ph.D. These studies led to identification of a set of rare variants in TREM2 that occurred more often in 1,092 Alzheimer's disease patients than in a control group of 1,107 healthy people. The most common variant, R47H, was then evaluated in follow-up studies of a large number of Alzheimer's disease patients and controls. Minerva Carrasquillo, Ph.D., a scientist in the Mayo Clinic in Florida laboratory of Steven Younkin, M.D., Ph.D., spearheaded the direct genotyping and analysis of R47H in DNA samples from 1,994 Alzheimer's disease patients and 4,062 "control" participants — individuals verified not to have Alzheimer's. The patients and control participants were evaluated by Mayo Clinic physicians, led by co-authorsDennis Dickson, M.D., Neill Graff-Radford, M.D., and Ronald Petersen, M.D., Ph.D.
Study Offers Clues to Cause of Brain Tumors in Children
Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children. In new research, scientists at Washington University School of Medicine in St. Louis have identified a cell growth pathway that is unusually active in pediatric brain tumors known as gliomas. They previously identified the same growth pathway as a critical contributor to brain tumor formation and growth in neurofibromatosis-1 (NF1), an inherited cancer predisposition syndrome. "This suggests that the tools we've been developing to diagnose and treat NF1 may also be helpful for sporadic brain tumors," says senior author David H. Gutmann, M.D., Ph.D., the Donald O. Schnuck Family Professor of Neurology. The findings were published online on November 14, 2012 in Genes & Development. NF1 is among the most common tumor predisposition syndromes, but it accounts for only about 15 percent of pediatric low-grade gliomas known as pilocytic astrocytomas. The majority of these brain tumors occur sporadically in people without NF1. Earlier research showed that most sporadic pilocytic astrocytomas possess an abnormal form of a signaling protein known as BRAF. In tumor cells, a piece of another protein is erroneously fused to the business end of BRAF. Scientists suspected that the odd protein fusion spurred cells to grow and divide more often, leading to tumors. However, when they gave mice the same aberrant form of BRAF, they observed a variety of results. Sometimes gliomas formed, but in other cases, there was no discernible effect or a brief period of increased growth and cell division. In other studies, the cells grew old and died prematurely. Dr.
Probing Mystery of the Venus Fly Trap's Botanical Bite
Plants lack muscles, yet in only a tenth of a second, the meat-eating Venus fly trap hydrodynamically snaps its leaves shut to trap an insect meal. This astonishingly rapid display of botanical movement has long fascinated biologists. Commercially, understanding the mechanism of the Venus fly trap's leaf snapping may one day help improve products such as release-on-command coatings and adhesives, electronic circuits, optical lenses, and drug delivery. Now a team of French physicists from the National Center for Scientific Research (CNRS) and Aix-Marseille University in Marseille, France, is working to understand this movement. They will present their findings at the 65th meeting of the American Physical Society's (APS) Division of Fluid Dynamics (DFD), November 18 – 20, 2012, in San Diego, California. The work extends findings by Dr. Yoël Forterre and researchers from Harvard University who discovered several years ago that the curvature of the Venus fly-trap's leaf changes while closing due to a snap-buckling instability in the leaf structure related to the shell-like geometry of the leaves. Mathieu Colombani, a Ph.D. student in Dr. Forterre's laboratory is now conducting experiments to elucidate the physical mechanisms behind this movement. "The extremely high pressure inside the Venus fly trap cells prompted us to suspect that changes with a cell's pressure regime could be a key component driving this rapid leaf movement," he notes. The Colombai team uses a microfluidic pressure probe to target and measure individual cells. This is a tricky experiment because it requires the living plant to be immobilized with dental silicone paste while the probe is inserted using a micromanipulator guided by binoculars. They take pressure measurements before and after leaf closure.
New Discovery Regarding Chromatin Remodeling Complexes
A new discovery from researchers at the Huntsman Cancer Institute (HCI) at the University of Utah concerning a fundamental understanding about how DNA works will produce a "180-degree change in focus" for researchers who study how gene packaging regulates gene activity, including genes that cause cancer and other diseases. The discovery, by Bradley R. Cairns, Ph.D., Senior Director of Basic Science at HCI and a professor in the Department of Oncological Sciences, is reported in the November 11, 2012 online issue of the journal Nature. Dr. Cairns's research focuses on chromatin remodeling complexes (CRCs), which are cellular protein complexes that behave like motors, expanding or compacting different portions of DNA to either express or silence genes, respectively. Before, scientists thought that the motor within CRCs waits at rest until it receives instructions. Dr. Cairns and co-author Dr. Cedric R. Clapier show that the motor within a key CRC responsible for gene packaging and assembly is intrinsically turned on, and instead requires specific instructions to turn it off. "Many articles in the research literature show that CRCs are mutated in cancer cells. They are intimately involved in regulating gene expression—responsible for correctly packaging genes that control growth proliferation and for unpackaging tumor suppressors," said Dr. Cairns. "This research reveals principles by which CRC mutations could cause cancer." Chromosomes are made of long DNA strands compressed around nodes of protein called nucleosomes; when DNA is compressed, the genes in that area are turned off. Some CRCs, called disassembly CRCs, act as motors that unwind sections of DNA chains, making genes active for a given cell process. Another type, called assembly CRCs, rewinds the DNA chain, recompressing it when the process is complete.
Class of Small RNA Molecules Protects Germ Cells from Damage
Passing one's genes on to the next generation is a mark of evolutionary success. So it makes sense that the body would work to ensure that the genes the next generation inherits are exact replicas of the originals. New research by biologists at the University of Pennsylvania School of Veterinary Medicine (Penn Vet) has now identified one way the body does exactly that. This protective role is fulfilled in part by a class of small RNA molecules called pachytene piwi-interacting RNAs, or piRNAs. Without them, germ cell development in males comes to a halt. Because these piRNAs play such an important role in allowing sperm to develop normally, the research indicates that defects in these molecules or the molecules with which they interact may be responsible for some cases of male infertility. Dr. Jeremy Wang, an associate professor of developmental biology and director of the Center for Animal Transgenesis and Germ Cell Research at Penn Vet, and Dr. Ke Zheng, a postdoctoral researcher in Dr. Wang's lab, authored the study, which appeared November 15, 2012 in PLOS Genetics. Scientists know of 8 million different piRNAs in existence; they are the most abundant type of small non-coding RNA. The molecule piRNA gets its name because it forms complexes with piwi proteins. Earlier work had indicated that these piwi-piRNA complexes suppress the activity of transposable elements or "jumping genes," which are stretches of DNA that can change position and cause potentially damaging genetic mutations. These sequences are also known as transposons. "There are about 50 human diseases caused by transposable elements, so it's important for the body to have a way to try to repress them," Dr. Wang said.
Gene Variant Distinguishes Early Birds from Night Owls; Helps Predict Time of Day One Is Likely to Die
Many of the body's processes follow a natural daily rhythm or so-called circadian clock. There are certain times of the day when a person is most alert, when blood pressure is highest, and when the heart is most efficient. Several rare gene mutations have been found that can adjust this clock in humans, responsible for entire families in which people wake up at 3 a.m. or 4 a.m. and cannot stay up much after 8 at night. Now new research has, for the first time, identified a common gene variant that affects virtually the entire population, and which is responsible for up to an hour a day of your tendency to be an early riser or night owl. Furthermore, this new discovery not only demonstrates this common polymorphism influences the rhythms of people's day-to-day lives -- it also finds this genetic variant helps determine the time of day a person is most likely to die. The surprising findings, which appear in the September 2012 issue of the Annals of Neurology, could help with scheduling shift work and planning medical treatments, as well as in monitoring the conditions of vulnerable patients. "The internal 'biological clock' regulates many aspects of human biology and behavior, such as preferred sleep times, times of peak cognitive performance, and the timing of many physiological processes. It also influences the timing of acute medical events like stroke and heart attack," says first author Andrew Lim, M.D., who conducted the work as a postdoctoral fellow in the Department of Neurology at Beth Israel Deaconess Medical Center (BIDMC) in Boston. "Previous work in twins and families had suggested that the lateness or earliness of one's clock may be inherited and animal experiments had suggested that the lateness or earliness of the biological clock may be influenced by specific genes," adds Dr.
Vitamin D3 Deficiency Linked to Type 1 Diabetes
A study led by researchers from the University of California, San Diego School of Medicine has found a correlation between vitamin D3 serum levels and subsequent incidence of type 1 diabetes. The six-year study of blood levels of nearly 2,000 individuals suggests a preventive role for vitamin D3 in this disease. The research appears in the December 2012 issue of Diabetologia, a publication of the European Association for the Study of Diabetes (EASD). "Previous studies proposed the existence of an association between vitamin D deficiency and risk of type 1 diabetes, but this is the first time that the theory has been tested in a way that provides the dose-response relationship," said Cedric Garland, DrPH, FACE, professor in UCSD's Department of Family and Preventive Medicine. This study used samples from millions of blood serum specimens frozen by the Department of Defense Serum Registry for disease surveillance. The researchers thawed and analyzed 1,000 samples of serum from healthy people who later developed type 1 diabetes and 1,000 healthy controls whose blood was drawn on or near the same date but who did not develop type 1 diabetes. By comparing the serum concentrations of the predominant circulating form of vitamin D – 25-hydroxyvitamin D (25(OH)D) – investigators were able to determine the optimal serum level needed to lower an individual's risk of developing type 1 diabetes. Based mainly on results of this study, Dr. Garland estimates that the level of 25(OH)D needed to prevent half the cases of type 1 diabetes is 50 ng/ml. A consensus of all available data indicates no known risk associated with this dosage. "While there are a few conditions that influence vitamin D metabolism, for most people, 4000 IU per day of vitamin D3 will be needed to achieve the effective levels," Dr. Garland suggested.
Pig Genome Sequenced
An international scientific collaboration that includes two Kansas State University researchers is bringing home the bacon when it comes to potential animal and human health advancements, thanks to successfully mapping the genome of the domestic pig. The sequenced genome gives researchers a genetic blueprint of the pig. It includes a complete list of DNA and genes that give pigs their traits like height and color. Once all of the genetic information is understood, scientists anticipate improvements to the animal's health as well as human health, as pigs and humans share similar physiologies. "With the sequenced genome we have a better blueprint than we had before about the pig's genetics and how those genetic mechanisms work together to create (characteristics), such as the unique merits in disease resistance," said Dr. Yongming Sang, research assistant professor of anatomy and physiology at Kansas State University. For three years, Dr. Sang worked on the genome sequencing project with Dr. Frank Blecha, associate dean for the College of Veterinary Medicine and university distinguished professor of anatomy and physiology. A report of the international study appears as the cover story of the November 15 issue of the journal Nature. The sequencing effort was led by the Swine Genome Sequencing Consortium. Researchers with the consortium inviting Drs. Sang and Blecha to work on the project because of their expertise and published studies on the antimicrobial peptides and interferons that pigs use to genetically defend themselves against disease. Drs. Sang and Blecha focused on these two families of immune genes, looking for gene duplications and gene-family expansions throughout the pig's 21,640 protein-coding genes, in an effort to help scientists with future pig-related research. Dr.
Origins Matter for Brain Tumors
Cancers arise when a normal cell acquires a mutation in a gene that regulates cellular growth or survival. But the particular cell this mutation happens in—the cell of origin—can have an enormous impact on the behavior of the tumor, and on the strategies used to treat it. Robert Wechsler-Reya, Ph.D., professor and director of the Tumor Development Program in Sanford-Burnham's NCI-designated Cancer Center, and his team study medulloblastoma, the most common malignant brain cancer in children. A few years ago, they made an important discovery: medulloblastoma can originate from one of two cell types: 1) stem cells, which can make all the different cell types in the brain or 2) neuronal progenitor cells, which can only make neurons. Stem cells and progenitor cells are regulated by different growth factors. So, Dr. Wechsler-Reya thought, maybe the tumors arising from these cells respond differently to different therapies. In a study published October 8, 2012 in the journal Oncogene, he and his team show that this is indeed the case. They looked at one growth factor in particular—basic fibroblast growth factor (bFGF)—and found that while it induces stem cell growth, it also inhibits neuronal progenitor cell growth. What's more, the researchers discovered that bFGF also blocks the growth of tumors that originate from progenitors. When they treated a mouse model of medulloblastoma with bFGF, it dramatically inhibited tumor growth. Although bFGF itself can't be used as a drug (it would cause too many off-target effects), this study suggests that molecules like it might be used to treat medulloblastoma—but only for tumors that have the appropriate origins. "Medulloblastomas are not all alike, and the same is true for cancers of the breast, prostate, and other tissues.


The SuiteBlanco fall/winter 2014-2015 collection comes to enrich the fall fashion world with more stunning clothing suggestions meant to grant sassy fashionisers with fresh and chic looks. Stunning supermodel Maryna Linchuk is the hottie featuring in the SuiteBlanco fall/winter 2014-2015 campaign, donning a line of elegant ensembles, as well as cool casual piece and outerwear options. What's more, you can get all these trendy pieces at such affordable prices that updating your fall wardrobe with the biggest trends of the season is a whole lot easier now!
Kind of a polish allure and a high dose of femininity and elegance embed every single pieces demonstrated in the SuiteBlanco fall/winter 2014-2015 campaign. That may be not only because of the minimalist, yet totally enchanting shapes, but also the timeless color palette chosen. Lots of pure whites and timeless blacks catch your attention instantly, while touches of glitter, fashionable khakis and dark red motifs make an appearance later to break the two-color mood and inject some excitement into the collection. Most of the pieces are monochrome with the focus placed on the interesting play of textures, glittery details and fab shapes that certainly lead to a better outcome one could ever expect!
Femininity and elegance are praised a lot in the SuiteBlanco fall/winter 2014-2015 collection, the result of which is a rich array of timeless pieces ideal to be sported to the office, as well as to the street on the days when you want to channel ladylike grace and chic. There you have a big variety of chic LBDs and white little dresses, being ideal outfit suggestions of special parties. Crips white flowy shirts, lovely knitted blouses and soft pleated mini skirts in white are other trendy items you'll fall in love with. However, it doesn't stop here, since we later discover the retro-inspired high-waisted printed full skirt matched with a black top, the structured black tops with short sleeves, the elegant tailored pants, the leather ones, as well as some uber-dazzling outerwear pieces ideal to top all these elegant outfits!
Fans of an alternative style than the feminine and elegant one also have stylish goodies to choose from in the SuiteBlanco fall/winter 2014-2015 collection, since the collection also shows a cool khaki parka and a glittery pencil skirt, meant to take your party styling to a whole new level. Moreover, the Spanish label presents a rich array of denim-wear options and casual pieces for fans of the effortlessly chic day-to-day style! So head to the store and discover it all on your own!


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Web Technologies we will offer you an informed choice of web designing services that can potentially meet your requirements in a number of different ways, giving you the opportunity to pick a solution that best fits your needs from a number of options for your specific requirements.We are a small team of extremely skilled professionals who can help you with all your web design and graphic design needs from creating a logo / branding to designing and hosting your website. We can create a brand and a web identity for you regardless of your business size. We provide web designing services including website design, graphic design, website hosting and domain names at an affordable price.
We can also help add features to any existing websites that you may have and work to your specific requirements. We believe every customer is different and needs customized pages to offer their business its unique identity that it deserves.
We work closely with all our clients and guide them in developing a solution specific to their particular requirements. We make their website reflect their corporate image and give their business a strong identity. Once a website has been built, we will also deliver targeted traffic using our state of the art search engine optimization techniques. Even a great looking site will not be successful online if it is does not reach the right audience. With our specialized search engine optimization service, we ensure that your site is found in the top search engines across the globe. We provide our clients a variety of concepts and directions and work hand in hand with them to produce an appropriate solution that exceeds industry standards.
We are providing quality web designing services with web site design, specifically tailored for small and medium sized businesses. We offer a range of web services from web design, web site marketing, search engine optimization, e-commerce, self updatable web sites, content writing, etc.. We have a major focus on customer service to ensure that we deliver the best web site results to you. Our high-caliber professional web designers, guarantee that our clients acquire a high quality website that will not only achieve all its objectives, but also surpass your expectations.
It is significant not only to have a website that looks good but also one that is designed in such a way as to give you good rankings with the search engines. This involves development of keywords relevant to your website and then we add the relevant key words and meta descriptions to the coding of each page to reflect the information on that page. We also ensure that the coding is dene in a way that makes the site search engine friendly.
We also do SEO optimization of the websites that were not developed by us. Get in touch and we will have a look at your website and work out a plan of action to recover its position in the search engines.
Our Graphic Designing services includes designing leaflets, logos, letterheads to business cards and posters. In addition to designing your web site we can help with.
For the logo and branding our team develop some options of design which you can then comment on. After initial discussions we take your favoured elements and develop them into additional options so that collectively we get a format that you are contented with. Our team produce an outline format and design and ensure that all the elements are portrayed in an effective way. Once the logo is agreed we will then develop options for each of the remaining items and fabricate a final adaptation of each.
Development of a corporate image.
Design and printing of all types of promotional literature.
Design of stands for trade and consumer events.
We also develop web based applications to fulfil needs of small to medium enterprises. Our team is specialized in Designing and Developing Web-Based Applications by Using the Microsoft .NET Framework. Our team also expert in developing web based streaming /e-learning solutions.
Application development is the substance of customization; it depends upon clients precise business prerequisite.
We are experienced professionals to develop advanced systems with complex business logic dealing with large amounts of data and transactions. We will supply you with most desirable, innovative, user friendly web application solution.
Hosting with Go Web Technologies is quick, easy and affordable. Our flexible packages allow you to require a web presence whether it be for home, business, ecommerce, professional or corporate websites. All packages are feature rich and offer great value and are easy to set up.


We would love to have you serve with The Lighthouse Events and help us spread the Good News of Jesus Christ through music. To help make our events run smoothly you can serve in areas like loading equipment, security, ushering, taking tickets or hospitality. If you love to serve and meet other Christians, then come join us! We can't do this without you! You will be provided a Volunteer Badge.
Once we receive your approved background check our Volunteer Coordinator will correspond with you through email to set up your next volunteer opportunity.


How do I delete photos from my iPhone after importing to my computer?
It becomes so disturbing when we are set to delete photos from iPhone after import for recycling, selling, or giving them out to charity, and we get to a touching point that most of our photos are still opened to recovery even after deleting. And with the statistics that shows that "1 out of 14 Americans are victims of identity theft," by US Department of Justice, we become more terrified between the dilemma of holding back to old iPhones or letting them go and be vulnerable.
The worry has come to an end and here is a great news for iPhone users, even the iPhone X and iOS 11 users; there is a way out of this mess and it the awesome privacy protector, iMyFone Umate Pro! With which, you can permanently delete photos from iPhone after import.
There are many lousy apps out there promising to give a delivery of "total erasure of photos" but are either not delivering at all or just deleting from physical folders to hide them as junks somewhere. Fortunately, iMyFone Umate Pro is not here for games, it can completely delete photos from iPhone after import without any slight chance of recovery by any app, agency, even the FBI.
It allows you to do a 1-click export & delete photos.
It can erase all photos permanently without any chances of recovery.
Total erasure is not limited to photos, as it can also permanently erase videos/website data/messages/call history/third-party app, and other private applications.
It can also scan and permanently delete files that have been deleted on iPhone.
It offers you a guarantee of being the best tool to help you keep your privacy on iPhone intact.
At this stage you are expected to delete photos from iPhone after importing to Mac/PC by installing and launching Umate Pro on your PC or Mac. After which, connect your iPhone to your computer by using a compatible USB cable.
On the software interface, choose "1-Click Free Up Space" tab where you can click the "Photos" button that would make you run a quick scan of your iPhone.
When you are done with scanning, you will see details on how much space can be saved with photos. Click on "Export & Delete" button, this will immediately export your photos to computer and also delete them from your iPhone.
Step 1: You will launch the Photos app on your iPhone or iPad, open albums in the bottom right corner.
Step 2: Then click on the photo you want to delete, and tap the Trash icon in the right side of your screen and tap the Delete (x) Photos to confirm the photos you want to delete.
Step 1: Connect your iPhone to your Mac, then launch Image Capture.
Step 2: Press Command+A to do a quick select all on the images.
Step 3: Click the red delete icon, and all the photos on your phone will be deleted instantly.
If you feel you still need some photos, make sure you have backups before you use this option or click the "Import All" button to import them to your Mac before the whole deleting process.
This is another approach to deleting iPhone photos after importing to Mac.
Step 1: Connect your iPhone and then launch Photos app on your Mac.
Step 2: Choose the photos you want to delete and then press command + delete.
Step 1: Connect your iPhone to the Windows PC, then go to your iPhone's DCIM folder within the Windows Explorer.
Step 2: Select your unwanted photos or you can press Ctrl + A to select all. You can delete them by right-clicking or pressing Shift + Del to delete them from your iPhone.
You should know that the above alternative methods have their cons as to their processes. It should be noted that deleted photos with these alternative methods can still be recoverable through the use of recovery programs . It is advisable to go for one-in-all app, the iMyFone Umate Pro and use Erase Deleted Files mode to complete the deleting process.


This car just came out of the garage 2 weeks ago for the first time in 17 years!!!! TheOhio tag went out of date in 12/99. Was running and driving perfectly when put into the garage. Needless to say the brakes will need to be done,and clean the carbs out........The only rust on the car is pictured on both driver / passenger floor pans about 4" wide x 24" long. This is typical as the roof always leaks water when it rains where the top meets the windshield and the door glass. Would love to keep it but I have over 60 cars / trucks and no time in the near future to give attention to this gem. please email with any questions or call 575-613-3480. Delivery may be possible depending on price and where you are.


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Keay, R.W.J. 1953. Kew Bulletin 1953: 69.
International Plant Names Index. 2016. Monocyclanthus. Published online. Accessed Aug. 16 2016.
Tropicos.org 2016. Monocyclanthus . Missouri Botanical Garden. Published on the internet. Accessed: 2016 Aug. 16.
This page was last edited on 31 December 2018, at 06:03.


text:
Q: Generalized homomorphism theorem Let $f: G \rightarrow G'$ be a group homomorphism with kernel $H$. Then we know as an elementary fact of abstract algebra that there is an injective group homomorphism $f^*:G/H \rightarrow G'$ such that $f^*(x+H) = f(x)$. More generally, let $\psi: G \rightarrow G/H$ be a surjective homomorphism with kernel $H$. Then again we have an injective homomorphism $f_{\psi}^* : G/H \rightarrow G'$ defined by $f^*_{\psi}(x+H)=f(y)$ where $\psi(y) = x+H$.
Could you verify the validity of this reasoning?
Thanks.
Edited:
To give you an example about the motivation of this question, we know that given
a homomorphism $f:G \rightarrow G'$ with kernel $H$ there exists always a homomorphism
$f^*: G/H \rightarrow G'$ such that $f = f^* \circ \phi$ where $\phi:G \rightarrow G/H$ is the canonical mapping.
Now, what if instead of the canonical mapping $\phi$ we have another surjective homomorphism $\psi:G \rightarrow G/H$ with kernel $H$? Does then exist a homomorphism
$f^*_{\psi} : G/ H \rightarrow G'$ such that $f = f^*_{\psi} \circ \psi$?

A: By the first isomorphism theorem there is a unique $\psi^*:G/H\to G/H$ satisfying $\psi^*\circ\phi=\psi,$ which must be an isomorphism since it is injective. Let $f^*_\psi:=f^*\circ(\psi^*)^{-1}.$ Then $$f^*_\psi\circ\psi = \left(f^*\circ(\psi^*)^{-1}\right)\circ\psi = f^*\circ\left((\psi^*)^{-1}\circ\psi\right) = f^*\circ\phi=f.$$

redpajama_set_name: RedPajamaStackExchange


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Set your content mission to achieve your business goals.
Select information your audience are seeking and audit existing content.
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Calculate your ROI resources needed over potential.


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Catch stand-up comedy at Northern Lights on Nov. 7
Carlee Wright
Laughs abound at Northern Lights Theatre Nov. 7. The pub is hosting two comedians, Quinn Dahle and Ed Hill, for two shows.
Dahle performs witty, clean comedy that appeals to all. Originally from Minnesota, he settled in Los Angeles, California, to pursue his career in comedy. He draws the audience in with his improvisational, spontaneous crowd work.
He has appeared on "The Tonight Show," "Lopez Tonight" and "Last Call with Carson Daly," as well as Showtime and Comedy Central networks. Performing at clubs, colleges and corporate events, Dahle has worked with Robin Williams, Drew Carey, Tim Allen, Dane Cook, Dana Carvey, Norm McDonald, Jon Lovitz, Bill Maher, Frank Caliendo, David Alan Grier, John Witherspoon, Tommy Chong, John Pinette, Harland Williams and others.
He currently is developing a sitcom based on his life.
Capitol City Theater offers comedy 5 nights a week
Hill is an emerging comic from Vancouver, BC. He uses the term Canasian to describe his situation as he moved to Canada from Taiwan 20 years ago — although his dad told him they were just going on vacation.
Inspiration for his honest comedy comes from everyday life, social situations and his family.
Jay Owenhouse brings magic, illusions to Salem Nov. 6
He was voted "Best Vancouver Comedian of 2015" by West Ender Magazine and "Best Local Stand Up 2015 Runner-Up" by The Georgia Straight. Canadian Immigrant Magazine named him a "Comic to Watch." Hill has appeared on AXS TV's "Gotham Comedy Live," Bite TV's "Stand up & Bite Me" and XM Radio's "Laugh Attack." He has performed at numerous comedy festivals around the world.
Seating is reserved. Seat numbers will be issued when tickets are printed. The theater recommends attendees arrive 30 minutes in advance to check in. Stand-up comedy at Northern Lights is intended for a mature audience. Some material may be objectionable.
Email cwright2@statesmanjournal.com, call (503) 399-6671 or follow on Twitter @CarleeWrightSJ
Lights, Comedy, Laughs! Live Stand-up Comedy
When: 7 and 9 p.m. Saturday, Nov. 7
Where: Northern Lights Theatre Pub, 3893 Commercial St. SE
Age: 21 and older
Information: (503) 585-4232 or northernlightstheatrepub.com
More comedy on Saturday
Comedy at The Bistro
What: A night of food and fun with comedians Eric Alexander Moore, Ken Hamlett and Dash Thompson. Cost includes dinner of lasagna, Caesar salad, soft drink and cheesecake. Beer and wine available for purchase.
Where: Main St. Bistro & Coffee, 201 E Main St., Silverton
Information: (503) 874-1234


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> CFPs > CFP – Aesthetics of the Future: The Cinema of Jean-Pierre Bekolo
CFP – Aesthetics of the Future: The Cinema of Jean-Pierre Bekolo
(African Studies, Film Studies)
Title: Aesthetics of the Future: The Cinema of Jean-Pierre Bekolo
Editor: P. Julie Papaioannou, Ph.D.
Associate Professor of Instruction in French
and Francophone Studies
French Language Coordinator
Lattimore 427
julie.papaioannou@rochester.edu
Aesthetics of the Future: The Cinema of Jean-Pierre Bekolo aims to collect peer-reviewed essays for a critical retrospective, and new emerging trends in the work of Cameroonian filmmaker Jean-Pierre Bekolo.
Bekolo's filmmaking spans three decades bridging the end of a century with the beginning of a new millennium, and his contribution to African filmmaking and criticism has consistently reached aesthetic and experimental milestones by projecting, reshaping, and boldly responding to
questions about representation, narrative, production, exhibition, and distribution.
In 1992, Quartier Mozart heralded the future of African filmmaking with a new and upbeat aesthetic orientation in an amalgam of postmodernist and postcolonial thought. Almost thirty years later, his latest feature, Miraculous Weapons (2017) highlights Bekolo's commitment to generate a critical discursive spin on questions of aesthetics, modernity, and postmodernity.
The goal of this edited book is to revisit contemporary approaches in African film criticism by focusing on critical perspectives in Bekolo's art while expanding a fresh inquiry in the artist's active engagement with crossing visual, narrative, filmic, theoretical, discursive borders, to name
a few; Bekolo's blurring of (post)modern and postcolonial boundaries with Afrofuturism, for example, highlights the director's commitment to challenge critical paradigms not only in African filmmaking but also in broader artistic domains.
In addition, this edited volume invites scholarly readings and insights on questions of technical aspects, soundtracks, photography, and visual effects that have rendered Bekolo's filmmaking new and fresh. The aim is to collect papers for a planned volume that will provide a concise underpinning of the filmmaker's overall work.
Tentative Schedule and Deadlines:
Contributors may express their interest by sending a 200-word abstract, a bio blurb with contact information (email, phone number) and institutional affiliation to P. Julie Papaioannou at julie.papaioannou@rochester.edu by December 15, 2021.
Papers should be approximately 20-25 pages, Times New Roman, Font size 12. Details will be discussed with publisher and will be provided.
Deadline for book chapter drafts May 15, 2022.
Deadline for revised chapters September 30, 2022.
Deadline for submitting manuscript to publisher-end of Fall 2022 (Date TBA)
Concordia College – Instructor – French Immersion
CFP – Journal of Multilingualism


Ace tennis player Sania Mirza took to social media to announce the news of her pregnancy. The sportsperson who is married to cricketer Shoaib Malik, shared a cute graphic of a wardrobe with the middle cabinet reserved for the Mirza-Malik baby, complete with a onesie and feeding bottle. We loved the innovative way the to-be parents chose to make this announcement. Husband Malik too posted the same image on his social media feed. Check it out below.
Mirza and Malik got married in 2010 but she did face a lot of flak from trolls for her decision to marry a Pakistani cricketer. Being the strong-willed woman she is, it did not stop Sania from pursuing her career in tennis, representing India on global platforms and continuing to reach new heights.
This announcement marks a new chapter in the couple's lives and we wish them all the luck for it. Congratulations Sania and Shoaib.


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Home > All > The King's Revenge: Charles II and the Greatest Manhunt in British History
The King's Revenge: Charles II and the Greatest Manhunt in British History
When Charles I was executed, his son Charles II made it his role to search out retribution, producing the biggest manhunt Britain had ever seen, one that would span Europe and America and would last for thirty years. Men who had once been among the most powerful figures in England ended up on the scaffold, on the run, or in fear of the assassin's bullet. History has painted the regicides and their supporters as fanatical Puritans, but among them were remarkable men, including John Milton and Oliver Cromwell. Don Jordan and Michael Walsh bring these remarkable figures and this astonishing story vividly to life an engrossing, bloody tale of plots, spies, betrayal, fear and ambition.
Manufacturer/Publisher: Abacus
Author: D. Jordan & M. Walsh


Professionalism, Patience, Creative, Fun, Amazing...the list goes on!
From the first instance, now we are talking back at our engagement drinks, we booked Kam to capture our event and we knew from then he was the man to have for our Wedding.
Kam made us feel so welcomed, even invited us round to his home, from the beginning and made sure we knew we were in good hands.
From the Pre-Wed shoot, through to Pre-wedding parties, Civil Ceremony, Wedding and Wedding Reception Party Kam pulled out all of the stops. Kam and his team would make sure everyone felt comfortable and he knew exactly what to do to capture the best images. There was never a moment where we would have to ask Kam for anything, he was there with his team ensuring all the fun, emotional and key moments were captured at the correct time.
When Kam gave us a sneaky peak at some of the images captured we were speechless. Now we knew Kam's work was good but this was on another level.
Kam was fantastic during the process of designing and building our wedding album. Ensuring we included all the key moments and capturing all of the emotions from immediate family, we couldn't wait to get our hands on the album and show them to family and friends.
Kam being Kam went back to his usual self of pulling out the stops when it came to giving us the wedding album. Kam threw in some really nice surprises that has allowed us to share the best week of our lives with our loved ones.
Now I am a firm believer in investing in quality. This is something I tell all my friends who have proposed and looking for a photographer. These are the moments that you want to make sure is captured in the best possible way, you want to capture all the fun, excitements and emotions and it is with Kreative Klicks you can get this.
Thanks a lot Kam..no doubt we will be booking you for future family events! "