text:
Page 3, 9th March 1945
Page 3, 9th March 1945 — Art True Church Art is more than an Advertising Art
Organisations: Central Institute of Art and Design
People: Felicity Sutton, Nan Reid, Augustus Lunn, Charles Murray, Stanley Spencers, Adam Kossowski, Matthew Smith, Howard Faulkner, Michael Ayrton
Locations: Jerusalem
Page 3 from 7th July 1939
Religious Art And The Search For God
A Portrait Of The Faith As Young Art
Weaving The Old And The New
The Exuberance Of Frank Brangwyn
Art True Church Art is more than an Advertising Art
Keywords: Fauvism, Paul Gauguin, Adam Kossowski
RELIGIOUS PAINTINGS AND DRAWINGS
THIS exhibition of religious
paintings and drawings which Messrs Mowbray had the initia
live to bring into being by instigating a competition, and which the Central Institute of Art and Design judged and organised, is an illuminating eerieience. It shows uncontrovertibly how deep the fissure is between the artist and the Church on the debit side, and ton ate credit side it shows how earneAly the artist is trying to unite, himself once again with the religious I radition. • The question is bow ? Imitations abound. A modem master, such as MatthewSmith, does not despise the imitative way, and using his own flamboyant colours and technique, produces a Last Supper in the wellknawn manner. Adam Kossowski's Jesus Bearing His Cross is a leser Rouauli, Nan Reid's Journey into Jerusalem is a Gauguin, Augustus Lunn's Jacob's Dream is a blend of Blake and Armstrong. Howard Faulkner's Stations of the Cross follow after Gill, and there are countless numbers of minor Stanley Spencers. It is not necessarily a bad thing. especially while one is finding one's way across unfamtliar territory: to follow another's guidance, and some of these imitative pictures have deserved the prizes they wov, but none of them is forging that link which must be forged if the artist and the Church arc to have a right relationship-that is a free relation5hip based on understand
ing of each other's viewpoints. The
Church must he given the confidence by the artist to believe in the artist's integrity of spiritual vision, and the artist must he given the freedom by the Church to work out his spiritual vision in his own way.
WITH the exception of a few paintings, which I shall come back to later, there is nothing in this show to suggest that this mutual confidence
has been established. Most of the work suggests that the artist is sellconacious instead of God-conscious, and that he is trying desperately hard to give the Church the sort of picture it will stand for, while at the same time, being a bit of a devil, by either portraying. Gospel scenes in modern dress or by using a symbolistic technique. The result is that scriptures and dogmas are advertised or displayed -they are not interpreted.
This won't do either as art or as Church workmanship. Something much more vigorous and visionary is called for, and the artist. to be sure of himself, must understand and feel his subject more deeply. That is the first and absolute necessity.
FronT 'this collection three painters 'lid stoke me as thinkers as well as zompetent painters. The first prizewinner for a resurrection subject, Charles Murray. has portrayed a calm. detached, divine. but suffering-marked Christ emerging from the winding sheet of death, which is real and poignant. Michael Ayrton's Christ before Herod and Behold the Man. though stressing the humanity rather than the divinity of Christ, dre nevertheless works of pule art. Felicity Sutton's Conver.ion of St. Paul too, is a highly imaginative conception And it is on works like these three individual *ritual and spirited paintings that the new, free, spontaneous relationship between Church and artist could be
built.-(Leger.) 7. C.


This site is new and as it grows I will be adding many articles on the subject of genealogy. I do plan on offering either vlogs, live training, or pre-recorded videos in the future as well. Why should you read my posts? The quick answer is you should read them because you want to and find value in the tips and information that I will provide you. The only way to find out if what I write about is valuable to you is to read them! It really is a little circular, isn't it?
I hope that you will find value in what I offer here on the article portion of the website. First a little about myself. I was a hobby genealogist by the time I was in my early 20's. People tend to gravitate towards this hobby for a plethora of reasons but most commonly it is to find out more about your ancestors and to fulfill your sense of belonging. How people are introduced to it also vary but I find it is usually through the influence of others or to answer questions about your family.
My journey with genealogy started pretty early mostly due to my grandmother's interest in it. She would often talk about the family history when I was growing up and would show me family heirlooms and talk about where we came from. This became an official mission of mine to investigate much later in my early 20's. Although she was born in 1918, she was around for a lot of my early genealogy research and I relish those memories. I wish she could have been around for some of my major discovers later. Oh and DNA. How I wish I could have gotten a DNA test for her. That is an entirely different post.
I won't bore with every intricate detail of my genealogy journey! I just thought I would share how my interest in genealogy began. I have been through several careers changes over the years in search of something that I really wanted to do. Then one day after making an amazing discovery for a friend on her family tree she asked me, "Why aren't you a genealogist?" I am a genealogist said my brain! But, I knew she meant professionally. I was excited, could I? Dare I? Yes! A genealogist certification later and here I am. It took quite some time to get here and get a website.
My focus will not be blogging so I will not be churning out a new post every day. Because I simply do not have the time to research and run a blogging empire. I will promise to write regularly though and try to provide interesting articles for you to make use of. I welcome you to my website and hope you will enjoy what you find here.
Next Post Genealogy in 15 minutes a day.


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Bauüberwacher steht für folgende Berufe im Eisenbahnbau in Deutschland:
 Bauüberwacher Bahn
 Fachbauüberwacher

redpajama_set_name: RedPajamaWikipedia


text:
Q: Really confused with java pixel manipulation THIS part i'm confused with what these 3 hexadecimals are doing such as 00ff0000, and why they're bitshifted 16 or 8 places
 // Getting pixel color by position x=100 and y=40
    int clr=  image.getRGB(100,40);
    int  red   = (clr & 0x00ff0000) >> 16;
    int  green = (clr & 0x0000ff00) >> 8;
    int  blue  =  clr & 0x000000ff;

A: The pixel's color information is encoded in a single 32 bit integer. The lowest eight bits store the blue color information, bits 8 to 15 store green and 16 to 23 store red. Bits 24 to 31 store the alpha value. The code that you show first selects the right bits by masking them using the and operation. In order to do calculations with them they are moved to represent their actual values.
clr & 0x0000ff00

selects the bits at position 8 to 15,
(clr & 0x0000ff00) >> 8

moves the result by 8 positions to the right.

A: In
int  red   = (clr & 0x00ff0000) >> 16;

The & will zero out all bits except those that are wanted:
0x00123456 & 0x00ff0000 == 0x00120000

The bit shift will place these bits at the desired position:
0x00120000 >> 16 == 0x00000012 == 0x12

Similarly for the other two channels.
0x00123456 & 0x0000ff00 == 0x00003400
0x00003400 >> 16 == 0x34

0x00123456 & 0x000000ff == 0x56

The reason for this is that the ARGB format stuffs four bytes (alpha, red, green, blue) into one int: 0xAaRrGgBb. The RGB format is similar except it doesn't use the alpha (opacity) channel. The whole point behind the bit-shifting is to separate those bytes: clr == 0x123456 to red == 0x12 green == 0x34 blue == 0x56
Note that each byte (8 bits) is represented by two hexadecimal digits (4 bits each) in the hexadecimal notation, so shifting by 16 bits shifts by 4*4 bits = 4 hexadecimal digits = 2 bytes.

redpajama_set_name: RedPajamaStackExchange


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Beyond the Pitch
Updox: Making Healthcare Simple for Everyone
#Startup Buzz Posted 9/15/2017 by Ryan Helon
Updox Update
It's been a record-breaking year at Updox.
With more than 56,000 physicians and 72 million patients using its secure communications platform, Updox announced, in May, a $12.7 million preferred equity round.
Then, just a few weeks later, for the third consecutive year, this Dublin-based growth business was named to the Inc. 5000 list of America's fastest-growing private companies.
But perhaps the most exciting news coming out of Updox is the company's consistent and industry-leading success in connecting patients' entire care teams with each other and giving the foundation needed to provide truly effective value-based care.
"For healthcare to be successful, everyone in the ecosystem must be able to communicate—whether it's the healthcare provider, the specialist, the pharmacy, rehab, long-term care the patient or their family," said Michael Morgan, chief executive officer, Updox. "It's not just about sharing data—it's about being able to communicate and easily connect around topics that matter."
Providers need to be efficient so that the care they provide is effective.
Updox has always been about communications. Updox started with a web-based universal inbox that allows doctors and practices to manage all patient communications, referrals, faxes, and emails in one place.
As market acceptance accelerated, Updox's vision grew, too. The company built its business by developing the only fully integrated customer relationships management (CRM) platform for independent physician practices.
"Healthcare has to be efficient before you can be effective," Morgan said. "That's why so much time and energy has been spent on large systems for sharing data. While data interoperability is important, excellent healthcare is powered by communications. A lot of technology out there has either been overlooked by independent providers outside of health systems, or it's just a cool app that promises to make one process more effective. But that doesn't work. You have to be efficient first and get people engaged. That's what we did."
To Updox, that means widening the circle of easy communications to connect pharmacies, long-term/post-acute care, and acute-care providers to the patients and physicians using Updox.
Updox extends its connectivity platform to pharmacies.
Envisioning a comprehensive approach to connect pharmacies with physicians, patients, and authorized family members, Updox sought direction from the marketplace.
"We performed market tests with dozens of pharmacies to be sure there was a market fit," Morgan said. "We found—and this is the exciting thing about our business—that the Updox platform, as it is, adds the same type of benefits to pharmacies that it provides to our physician practices."
Pharmacists and assistants are super busy. They deal with lots of paper. They spend considerable time calling patients. Increasingly, patients are turning to community pharmacies for clinical services. Plus, every day, pharmacies are faced with one of the greatest challenges in healthcare today—medication adherence—helping ensure that patients following their physicians' therapies and take their medications as prescribed.
By expanding into other care settings, Updox is creating unique access points for other partners in the healthcare supply chain – such as payers or pharmaceutical companies – to give them a better way to influence behavior for things like medication adherence.
"What we're doing hasn't been done before at this level," said Morgan. "There hasn't been a full-scale communications solution like Updox that offers the same, secure, accessible communications channel to all the different providers within healthcare."
Updox expanded the partnership model that has been so successful in integrating the Updox platform with providers of electronic health records (EHRs) and practices management systems to include leading pharmacy management systems. Interfacing seamlessly with industry leaders that include Rx30 and Computer-Rx, Updox Pharmacy Connect provides pharmacies with the exchange of secure communications – including email, faxes, and forms – with physicians, payers, and patients.
Updox has nearly 100 employees, having added about 40 positions this year, and will continue to add staff. The company's thoughtful approach to market segmentation and validation, the deliberate process of building strategic business partner relationships, and the management team's ability to deliver on the business plan, has accelerated the company's growth.
"We have a recipe that works and a platform that builds value," Morgan said. "We solve pragmatic problems, prove a good market fit, and then develop solutions that simplify healthcare and people like to use."
The plan is to continue to build out the communications and human connectivity of the Updox platform and to segment the healthcare marketplace to more specifically address the needs of certain patient populations further.
"Updox is in a unique position to tie together whole healthcare networks to serve patient populations in ways that make patients, providers, pharma, and patients enthusiastic about the results," Morgan said.
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Channels must be selected from the same HOBO RX3000 and associated Smart Sensors and HOBOnet sensors. In general it's good practice to have the temp, RH, light, and wind sensors at the same location.
Both Hourly & Daily ET are availible to view.
In general, calculated channels are not available in the dashboard until data is available in the database. It can take up to one hour before Hourly ET is available; Daily ET is available after midnight.
Exported data will show ET at the top of each hour or day, depending on which of the two you are plotting.
When comparing hourly and daily ET, in some instances it could be off by 0.01 due to small rounding errors.


Your style is our passion!
Monkey 23 is a make-you feel happy, funky, daring, audacious and colorful brand.
2017-2018: After serving as a volunteer in post-Hurricane Maria Puerto Rico relief efforts and witnessing such a vast amount of destruction throughout the island, we made it our mission to bring back happiness and smiles to the beautiful people of Puerto Rico. With that purpose in mind, we established the first Hispanic funky-fashion company born in Puerto Rico, creating daring, passionate and colorful socks, apparel and accessories for the global market.
2018: The Monkey 23 Fashion Co. brand is launched. The company creates its first product: 16 unique socks with designs that represent Puerto Rico, Hispanics and our culture: "Latinos para el mundo" (Latinos for the World).
2019: In just four months after launching, the product line has grown to 32 successful designs of unique socks with 40 more in the pipeline, including designs for Dominican Republic, Cuba, Miami, Mexico and Venezuela. We focus on creating unique designs and themes paying special attention to quality. Only the softest combed-cotton is used for all our socks making them extremely durable and comfortable. Convenience is also a key characteristic of our product: our socks adjust to most foot sizes.
As a firm testimony of how our brand was born, Monkey 23 Fashion Co. will always have a sincere and firm commitment to our social purpose. As such we give back to the community by donating a percentage of our sales to the Hispanic Federation, the pioneer non-profit organization assisting Hispanics in need throughout the United States of America and Puerto Rico.
We are a funky, urban, edgy, sharp and cool professional. The creator of our global brand is a men who landed on his feet on a 23rd, already a step ahead, ready to walk at his own pace and flow.
The first sock collection developed by the brand will be known for making some of the funkiest novelty socks designs inspired in the Puerto Rican culture for the local and global market.
Show off your awesomeness and turn heads with these crazy cool threads.
This is a unique collection of high-quality socks with a funky style and a good dose of humor.
The assortment comes with 17 unique designs in one size.
You have a life to live, so have fun and spice up your life with Monkey 23!


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Shawnee, Okla. Artist Making a Stop in Glasgow During Art Across America Tour
Wheatgrass Arts and Gallery will be hosting an Artist Reception at the gallery, 523 2nd Ave. S., Glasgow, on Sunday, Oct. 13, from 4:30 to 6 p.m. for Douglas G. Gordon. Gordon is stopping in Glasgow on his Art Across America venture to promote art and artists throughout America.
After the reception, he will be hosting a one evening printmaking class utilizing monotypes and non-toxic etching. The cost is $45 and open to everyone over 14 years old and all skill levels. To register, contact the Wheatgrass Arts & Gallery at 230-0148 or e-mail [email protected] Slots are limited to 10 students in order to enable those attending to gain the maximum amount of knowledge and experience.
"I am really looking forward to meeting local Glasgow artists and artists from the surrounding area," says artist Gordon "I am also excited to be able to teach a class on monotypes and non-toxic printing at the Wheatgrass Arts and Gallery," he adds.
At the beginning of October, Gordon boarded his first train in Norman, Okla., and set forward to head south and then north to Chicago on a train before catching a bus northeast to St. Paul, Minn. He will spend six days there meeting artists, creating art and spending some quality time with family. From St. Paul, Gordon will head west on the Empire Builder to Glasgow and then west to the greater Seattle area before heading south to Portland and Los Angeles. After LA, Gordon will head east to Albuquerque and then north-east to Dodge City to meet with artists from the 2nd Ave Art Guild before heading home at the end of a long and exciting 'Art-venture.'
When planning his trip, Gordon saw that the Empire Builder train stops in Glasgow. "Having grown up in Glasgow, Scotland, I knew that I had to find an art reason for stopping off in Glasgow during my 'art-venture.' I used a search engine to find artists and galleries in Glasgow and I found listings for many artists and The Wheatgrass Arts and Gallery and I reached out to them to see if I could teach a class, in monotype and non-toxic etching."
He plans to use search engines to connect with other artists in other towns and cities along the way. "You might as well go big or go home," he says.
Gordon will be posting many photos and streaming videos to his Facebook 'Art Across America' page ( http://www.facebook.com/ArtAdventure2019/) during his trip as well as on his website at douglasggordon.com.


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Mum's anguish as son, 9, in hospital with rare Covid symptom
Cai Price tested positive for coronavirus in November
Cai Price (Image: Sally Price)
A nine-year-old boy has ended up in hospital with a little-known Covid symptom - despite only experiencing mild symptoms.
Cai Price tested positive at the start of November, and like most children who catch the virus his symptoms were very mild, being described as a 'slightly runny nose'.
Four weeks later however, and Cai became deeply unwell, with a high fever, severe fatigue, a bad stomach, swollen neck glands, cracked lips, and cold hands and feet, WalesOnline reports.
Cai was admitted to hospital where a medical examination found he had developed a Covid complication. It means Cai's immune system went into overdrive to attack infections.
"I am so angry that there is little to no information out there about this syndrome," said his concerned mother Sally Price.
"My intention isn't to scare anybody but to help raise much-needed awareness among parents. The doctors were beside themselves and concerned there could be an influx of further children being admitted to hospital."
Sally said her older son Dylan had many of the classic symptoms of Covid-19 including loss of taste and smell and a bad cough, but Cai was almost completely asymptomatic.
Cai Price (bottom left), nine, with his mum Sally and older brother Dylan (Image: Sally Price)
"Cai plays football six days a week so he was an extremely healthy, fit young boy with no underlying health conditions," Sally added.
He tested positive for coronavirus on November 1, started to become unwell in school on November 30 with neck pain which his family initially thought was a football injury.
"But on December 1 he started to present with a fever, and as time went on it began to look like symptoms of meningitis. So I contacted our GP who was fantastic. She said our best bet was to go to A&E."
At hospital, clinicians initially thought Cai had torticollis, also known as wry neck, a condition where the head becomes twisted to one side and it is very painful to move. They also thought he had a viral infection.
But just 24 hours after being discharged from hospital, Sally noticed Cai's neck had turned bright red and swollen - and the right side of his face had dropped.
This time the family travelled to a different hospital where a series of tests was carried out to find out what was wrong.
Sally added: "They initially thought it was an abscess on his neck. He had a CT scan but nothing was found. They then thought it might be an infection of the lymph nodes as his neck was so painful to touch."
As Cai was admitted to hospital he needed to take a PCR test which came back as positive the following day.
"By chance I informed the doctors that he'd had a positive test four weeks prior - that set alarm bells ringing for them," Sally recalled.
Cai was diagnosed with paediatric inflammatory multi-system syndrome, known as PIMS for short, which occurs when the body's immune system attacks an infection.
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Official NHS guidance says that PIMS can develop between four and six weeks after having Covid. Symptoms can include a prolonged fever, tummy ache, diarrhoea, vomiting, widespread red rash, red bloodshot eyes, strawberry red tongue, and red cracked lips.
In some children with PIMS the inflammation can affect the blood vessels, particularly those around the heart. If untreated it can cause tissue damage, poor function of vital organs, and even death.
Following constant dialogue between clinicians, Cai was given a course of steroids and monitored frequently.
It was discovered that PIMS had affected Cai's heart and given him "a leaky valve".
"His heart wasn't contracting as it should be. They were keeping a close eye on him through his blood pressure and pulse rate," Sally added.
"PIMS targets the heart and then goes to the other vital organs. Cai was very fortunate that his other vital organs hadn't been affected - it was literally just the heart."
After a week in hospital, Cai was discharged but is still being closely watched by the NHS. Their latest assessment found that his heart function - and the leak - had improved.
"He's on the mend. It's going to be a long road ahead but he's been a very brave boy and not complained or moaned. We're very lucky he's still with us. I am so grateful to the staff at Glangwili hospital, particularly Cilgerran Ward. I will forever be in their debt."
Royal Stoke surgeon headbutted as he walks home from work
Sainsbury's says sorry as store turns away angry shoppers
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House boarded up in street plagued by 'walking dead' monkey dust addicts
LIVE: Covid self-isolation rules changed while city sees massive rise in cases


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Q: Fedora 17 Performance Issues I have a Dell Latitude E4310. I have Windows 7 and Fedora installed on it. I rarely use windows and I have been using fedora for a good 9 months now. Recently the performance on my machine degraded considerably. I got a hardware servicing done as well however it continues to worsen each day. What tools can I use to analyze and further resolve the problem?
I have ample of disk space > 30 GB unused.

A: How do I diagnose a performance problem?
This question is too broad for this website, but I'll offer you the following tips only because I don't want you to feel like you're being blown off.

*

*Consult the output of top. Look for processes that are consuming either a lot of CPU and/or memory resources

*Check the output of dmesg, looking for any messages related to errors or anything that's failing

*Check log files, specifically /var/log/messages

*Make sure you're up to date, yum -y update

*Exercise the system using memtest86+
These are just a few of the things to get you started.

A: Try to use top to see which process consumes the more RAM/CPU. iostat can also be used to see which process uses your disk.


Gangplank Slipholders Association (GPSA): The Economic Stimulus Package: A Significant Step Towards a Sustainable Economy and Nation?
The Economic Stimulus Package: A Significant Step Towards a Sustainable Economy and Nation?
-Can D.C. become a hub of green jobs and opportunities?
Light refreshments To Be Provided!


As I click on a video from StandWithUs of a pro-Israel rally in London, I'm inspired. Hundreds of people line the road, flanked by tall blue and white Israeli flags. No speeches. No shouts. Just singing, peaceful and strong.
Cross it; if you're unafraid you can.
What world am I living in that such a rally is even necessary?
My generation of Diaspora Jews had Judaism and Israel on a silver platter. We didn't have to fight for it. It was just there, a given. Something rich and beautiful to enjoy, to feel anchored by, to be proud of, to call home.
Terror has plagued Israel since its inception, even before it became a state. But the existence and legitimacy of the Jewish state? This was not debated in Western society. Today, unbelievably, we need to fight and justify Israel's basic existence.
On the day of the London rally, a news article tells of Johannesburg's latest gift to the Palestinians: a towering statue of Mandela to be placed in Ramallah's town square.
Seriously? What a twisted perversion of the symbol of anti-apartheid. With the symbiotic relationship between Joberg and the Palestinians, perhaps the Palestinians should send South Africa a statue of Arafat — symbol of murder and bloodshed?
To be frank, I was disappointed. South Africa? Israel has done and continues to do so much in guiding and aiding South Africa with its technological innovations in order to help the still developing parts of this continent.
It's not worth engaging this distorted, nefarious and wholly inaccurate historical term — apartheid — when applied accusingly to Israel by her enemies.
Then came news of vandalism in the Virginia Vale neighborhood of my native Denver. Thirty six cars! Stars of David, anti-Semitic messages, racist graffiti….


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As the number of people moving to big cities rises, aren't we all becoming immigrants looking for a sense of home? The future of cities is often visualized as a high-tech, high-speed environment. What's the impact of this scenario on humanity? How about the cities' emotional side?
We all know retail is blending with different fields like work and hospitality lately. Some stores taking this intermix to a higher level. The future of retail is for those who dare to take a next step in being an experiential place. Do you dare to take your store into the future?


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Q: iOS - Automatically resize CVPixelBufferRef I am trying to crop and scale a CMSampleBufferRef based on user's inputs, on ratio, the below code takes a CMSampleBufferRef, convert it into a CVImageBufferRef and use CVPixelBuffer to crop the internal image based on its bytes. The goal of this process is to have a cropped and scaled CVPixelBufferRef to write to the video
- (CVPixelBufferRef)modifyImage:(CMSampleBufferRef) sampleBuffer {
    @synchronized (self) {
        CVImageBufferRef imageBuffer = CMSampleBufferGetImageBuffer(sampleBuffer);
        // Lock the image buffer
        CVPixelBufferLockBaseAddress(imageBuffer,0);

        // Get information about the image
        uint8_t *baseAddress = (uint8_t *)CVPixelBufferGetBaseAddress(imageBuffer);
        size_t bytesPerRow = CVPixelBufferGetBytesPerRow(imageBuffer);
        size_t width = CVPixelBufferGetWidth(imageBuffer);
        size_t height = CVPixelBufferGetHeight(imageBuffer);

        CVPixelBufferRef pxbuffer;
        NSDictionary *options = [NSDictionary dictionaryWithObjectsAndKeys:
                                 [NSNumber numberWithBool:YES], kCVPixelBufferCGImageCompatibilityKey,
                                 [NSNumber numberWithBool:YES], kCVPixelBufferCGBitmapContextCompatibilityKey,
                                 [NSNumber numberWithInt:720], kCVPixelBufferWidthKey,
                                 [NSNumber numberWithInt:1280], kCVPixelBufferHeightKey,
                                 nil];
        NSInteger tempWidth = (NSInteger) (width / ratio);
        NSInteger tempHeight = (NSInteger) (height / ratio);

        NSInteger baseAddressStart = 100 + 100 * bytesPerRow;
        CVReturn status = CVPixelBufferCreateWithBytes(kCFAllocatorDefault, tempWidth, tempHeight, kCVPixelFormatType_32BGRA, &baseAddress[baseAddressStart], bytesPerRow, MyPixelBufferReleaseCallback, NULL, (CFDictionaryRef)options, &pxbuffer);

        if (status != 0) {
            CKLog(@"%d", status);
            return NULL;
        }

        CVPixelBufferUnlockBaseAddress(imageBuffer,0);

        return pxbuffer;
    }
}

It all works fine, except that when I am trying to write it into the video's ouput using this method, it keeps receiving memory warning. It is fine if I keep the same ratio
- (void)writeBufferFrame:(CMSampleBufferRef)sampleBuffer pixelBuffer:(CVPixelBufferRef)pixelBuffer {
    CMTime lastSampleTime = CMSampleBufferGetPresentationTimeStamp(sampleBuffer);

    if(self.videoWriter.status != AVAssetWriterStatusWriting)
    {
        CKLog(@"%d", self.videoWriter.status);
        [self.videoWriter startWriting];
        [self.videoWriter startSessionAtSourceTime:lastSampleTime];
    }

    CVPixelBufferRef pxbuffer = [self modifyImage:sampleBuffer];
    BOOL success = [self.avAdaptor appendPixelBuffer:pxbuffer withPresentationTime:lastSampleTime];
    if (!success)
        NSLog(@"Warning:  Unable to write buffer to video");
}

I also tried with different approaches using CMSampleBufferRef and CGContext. If you can provide a solution for any approach here, I can give you the full score

A: Try to use kCVPixelBufferLock_ReadOnly flag in both calls to -CVPixelBufferLockBaseAddress and -CVPixelBufferUnlockBaseAddress.
And sometimes this issue can be solved by copying pixel buffer. Perform allocating once:
unsigned char *data = (unsigned char*)malloc(ySize * sizeof(unsigned char));

After that, copy data from pixelBuffer to data

size_t size = height * bytesPerRow;
memcpy(data, baseAddress, size);

After that, use data. Hope, that will help.


Win a family ticket to DogFest – the ultimate summer festival for dogs!
We're a team of dog lovers at eastlife so we've partnered up with DogFest, the UK's biggest and best day out for dogs and their families, to offer two lucky winners the chance to win a family pass to this fun-filled day out!
DogFest will take place in the stunning grounds of Knebworth House in Hertfordshire on Saturday 11 and Sunday 12 May.
This amazing weekend once again promises a packed schedule of celebrity appearances and expert talks, jaw-dropping dog displays, educational sessions and fun activities where the public – and their dogs – can join in. Everything is geared towards celebrating the amazing bond between dogs and people and promoting animal welfare.
With special guests Clare Balding and Supervet Professor Noel Fitzpatrick, a highlight of this year's event is 'The Great Dog Walk' (there are 2K and 4K routes). Clare will lead the walk and Noel will open it. He'll also front a special interactive feature for younger visitors.
Then there are seemingly endless have-a-go activities such as dog diving, Fido's Lido, flyball, agility, hay bale jumping and fun dog competitions. There's even mass participation dog yoga where pets and people can de-stress together.
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Why Bill Nye Didn't Win the #CreationDebate
I think Bill Nye had a far better scientific argument, but he didn't win because he failed to realize that the debate was never about science. It was about faith. His words "I'm not a theologian" were the precise reason why he couldn't convince a single person who believed in young-earth creationism to accept his perspective. For them, Ken Ham won the debate.
Which of them is the true scientist was obvious from the question "What would it take to change your mind?"
Ken Ham hemmed and hawed and argued his point again and again, but in the end, it was obvious that there was nothing that could change his mind because he was right.
Bill Nye said "One piece of evidence."
Assuming that Nye wasn't lying, he was the better scientist in the debate because he was willing to admit that he could be wrong and, by his protestation, would be incredibly excited to be proved so!
It's a matter of what's at stake. If Bill Nye is wrong, then he gets to learn something new and exciting. If Ken Ham is wrong, his entire belief system falls apart. As Micah J. Murray points out, "Young Earth Creationism was the foundation upon which Christianity was built." If that falls, everything falls.
For Bill Nye, what's at stake in the debate is the power and prowess of a country and the minds of young children being taught lies.
For Ken Ham, what's at stake is everything. Kids going to hell. Adults going to hell. The entire foundation of Christianity crumbling. His own deeply held religious beliefs being wrong. Ken Ham (and his followers) cannot psychologically allow themselves to believe that Bill Nye might be right. That's why the fight is so weird: It's not about figuring out the best science based on the evidence. it's about defending beliefs.
Bill Nye was going after the symptom. He chopped off one of the hydra's heads, and two more grew back. The heart of the debate is about how to read the first two chapters of Genesis.
When I took history classes, I disagreed with their points about how humans came into existence.
My transformation started with two conversations. The first was when one of my film professors told me that I needed to be willing to go wherever the evidence led – to actually believe in what I believed in, rather than protecting it by refusing to look at certain evidence. "It's not like we're going to one day look under a rock that will prove that God doesn't exist," he said. The second conversation was with my friend Rachel. She suggested that I listen to him. (I had no respect for this professor at the time, but I had a great deal of respect for Rachel.) So I took her advice. I held off judgment.
When I took theology classes, I learned that the point of Genesis was not to be a modern history or science textbook. It was a theological book. The key words that I learned were "Orienting Narrative." The creation narratives were the words of men trying to explain the world, and the spirit of God got involved in this particular telling, and that means that these words are more than just words. Converting them into a literal telling of how the world came into existence is not to take those words too seriously, but to not take them seriously enough.
When I saw this, creationism fell away without a shot. I no longer had a psychological need to reject the mainstream understanding of how the world came into existence. If acting as a science textbook wasn't the Bible's purpose (and it wasn't), then I was free to accept the evidence as it was presented to me. I was free, like Bill Nye, to go where the evidence led.
I have something in common with Ken Ham, though. I don't think there is anything that could convince me not to believe in God. Right now I'm not sure who God is, though. For me, God starts and ends with Jesus on the cross dying to save the world.
You can't disprove the resurrection. Even if one day someone could somehow find the physical body / bones of Jesus, I could just make the shift to believing in a spiritual resurrection. Nobody could ever disprove that. I do believe in the physical resurrection, and that would be hard, if not impossible, to disprove. Certainly there is the argument that that sort of thing doesn't happen, but that is precisely the sort of thing that would make it a miracle.
"If you believe in the physical resurrection, why not believe in six literal 24-hour days and a young earth?" Because I don't need to.
Belief in the physical resurrection of Jesus is essential to my understanding of Christianity and to my faith.
Belief in young earth creationism is not.
And this is why the Bill Nyes of the world will never defeat the Ken Hams on the creation vs evolution debate. They don't realize that, for the Ken Hams, it's not about science, and it never has been.
It's about faith.
Of course, the Ken Hams don't want to look stupid, so they build vast theories and arguments around their ignorance to protect their faith. Nobody wants to be a science denier, so they rewrite and redefine science to match their ends.
For Ken Ham, science is a tool to prove the Bible.
For Bill Nye, science is a means of wonderful discovery.
That's why a professor who used to teach at my school wrote this after the debate:
What struck me most was that Ham came across as a hard-nosed empiricist (by which I don't mean that his methodology is sound), while Nye radiated joy and wonder. His closing peroration would probably have convinced me to believe in God if I didn't already 🙂
–Edwin Woodruff Tait
Bill Nye's joy and wonder "would probably have convinced me to believe in God if I didn't already."
Further resources for what it is to be a Christian and believe in evolution are at biologos.org.
Author David M SchellPosted on February 5, 2014 February 11, 2014 Categories Theology
11 thoughts on "Why Bill Nye Didn't Win the #CreationDebate"
Jennifer Neyhart (@JenniferNeyhart) says:
I really like this post. Especially this: "I no longer had a psychological need to reject the mainstream understanding of how the world came into existence"
Belief in young earth creationism is not."!!!
That is fascinating, and I doubt the switcheroo is because they're playing a part for the sake of the audience. Bill Nye really is overcome with joy and wonder at the prospect of being proven wrong because he's a true believer in his epistemology. Ham, because he also believes that epistemology but simultaneously staked out unrelated claims on top of it, is not at all filled with joy and wonder at the prospect of being wrong. Essentially, Nye's locus of truth is outside himself, and Ham's locus of truth is inside himself, if you can just make up terms like that.
Nye worries about where the evidence leads him, and Ham worries about the Bible and his existing set of hermeneutics. Both are flawed, and both for the same reason: There's no practical protection for flawed human reason.
What theological import would a young-earth vs. old-earth view have? Where in history has the argument over this been as important as the arguers make it out to be? I've never really gotten a good answer to this, other than a cross-reference to somewhere else in the Old Testament. There's never been a connection to clear theological principles, to clear ideas — other than the apparent assumption that to draw any other conclusion undermines sola scriptura. I don't know how they get that connection, but that seems to be what they're saying.
David Schell says:
"Nye's locus of truth is outside himself, and Ham's locus of truth is inside himself, if you can just make up terms like that."
I don't think that you made those terms up, but even if you did, I think that you should be able to, because that was awesome.
Hannah Keefer says:
I believe that tangling up young earth creationism, abortion, and homosexuality up with essential tenets of the faith, as Ham does, is responsible for a LOT of young people abandoning their faith entirely once they hit college. These young people reach a point where they start hearing new viewpoints and thinking for themselves, and sometimes they land on a different side of the debate than their parents did or their church did. Problem is, they've been told all their lives that they can't believe any of the things on this forbidden list AND have faith in God. So, much of the time, God is simply gone. "I believe this, so I guess I'm not really a Christian anymore." Rather than finding a way to hold onto faith and wrestle through the issues, they're stuck with this black-and-white either-or option that never allows them the opportunity to grow and change in their doctrine.
So true, Hannah.
Mike Rogers says:
Bill Nye, the scientist, honestly stated, "I am not a theologian." But Ken Ham was not as honest as Nye since he is not a theologian either. Any degrees he has in religion are honorary and not earned.
Edwin Tait says:
Hannah, one of the exhibits at the Creation Museum concerned someone (not someone I'd heard of, but it was in the late 19th or early 20th centuries) who allegedly lost his faith because he came to believe in evolution. I stood there looking at this guy's picture and I thought, "Why can't they see that this is an argument against their case–he concluded that if evolution is true then Christianity is false, because he'd been taught that these were mutually incompatible." So I think they see the same phenomena you're talking about, but they interpret them differently. You and I (and we're right of course!) see people being driven away from the faith by the insistence that they must be creationists. The creationists see people being lured away from the faith by evolution.
Ubiquitous, there are two basic issues with young-earth vs. old-earth. One, of course, is Biblical literalism. As you say, many fundamentalists think that if you question what Ham calls the "natural" reading of Genesis (which Ham and many fundamentalists think is a "historical" reading), then you have no "objective" way of interpreting any part of Scripture, which undermines the authority of Scripture. Now this isn't as big an issue for me, because I don't believe in sola scriptura. But the fact is that the great conservative Protestant theologians of the 19th and early 20th centuries, including staunch defenders of inerrancy like Hodge and Warfield, had no problem with old earth. (Hodge rejected evolution; Warfield initially accepted it and then became a bit more skeptical later, but never completely ruled it out.) They weren't what we'd now call "literalists," and they had no problem maintaining sola scriptura and Biblical inerrancy.
The other issue, which is a lot more serious from my perspective, has to do with the origin of death and "natural evil" generally (suffering, sickness, etc.) Even if you believe in special creation of human beings and other "kinds," if you accept an old earth you must believe that animals suffered and died (on a vast scale) before there were any humans to sin. This isn't a problem for everyone–in my experience Catholics (even very conservative ones) don't seem to worry about this the way Protestants do. I'm not sure what's going on there. But from my perspective it's the one serious argument the young-earth creationists have.
John Cross says:
Great post! I love how you don't see your faith as depedent on how the earth came into existence. I don't either, but I am still believe in a young earth. From my studies I have seen most of the evidence pointing to a young earth, and not out of making excuses or feeling like my worldview would come crashing down if it didn't.
If I can share thoughts about the debate, I think that Nye did a better job asking questions and debating but was also a bit unfair. For instance, he centered the debate around the issue of if the earth was 6000 years old or not while Ham was mainly prepared to talk about the approaches of the scientific method. Nye did a better job of steering the debate, but was also unfair when he blasted Ham with question after question in his 30 minute presentation, knowing that Ham wouldn't have time to answer in the following 5 minute rebuttal. And to top it off he came back several times to say, "But you still didn't answer my question on this!" Not to mention that he got onto other topics during the Q&A time. Ham, however, started his 30 minute presentation with sharing his views but not doing much debating or asking many questions for Nye to answer.
David, I love your point about the debate being more about faith. I definitely agree. On the surface it was more about a young earth vs. old earth which is why Nye did a better job in debating (though I still agree on Ham's views, just feeling like he didn't express them well). But underlying it was each proponant's deeply rooted worldview.
James 'J' Hunt says:
So wrong Hannah. It's not an us vs them argument. The ones who make it this totally missed Jesus's message. For God loved the WHOLE world. He loves all of us and his grace is for all of us. The only requirement is we accept it.
George Staelens says:
Although I am a Belgian and not acustomed with tose two people, I watched the debate too. I also found Bill Nye praiseworthy, civilized, polite… while Ken Ham was rude, proud, and lacking of arguments. Yes, an old-earth creationist would have had a read science debate with Bill Nye, and Ken Ham was not the right person for such a debate.
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Civil Rights Violation Lawyer David Perecman Weighs in on Swiss Apology to Oprah Winfrey for Perceived Racist Treatment at Zuric
Civil Rights Violation Lawyer David Perecman Weighs in on Swiss Apology to Oprah Winfrey for Perceived Racist Treatment at Zurich Shop
Posted on Aug 13, 2013 7:35pm PDT
The Swiss Tourism Board apologized to Oprah Winfrey following an incident of alleged racism. According to the Chicago Sun-Times (8.9.13), Winfrey was in Zurich and shopping at a luxury store when she asked to see a handbag. The shop assistant refused to let her see the bag, telling her she would "not be able to afford it," Winfrey quoted the shop assistant as saying. After the incident made international headlines, the shop denied any racism was intended. To civil rights violation lawyer David Perecman, the story, as told by Oprah, sounded like a racist incident.
Winfrey said she asked to see the bag more than once, but the clerk repeatedly refused to show it to her, said the Chicago Sun-Times. The handbag at the center of the incident is a $38,000 crocodile-leather Tom Ford design. Winfrey, one of the most famous television personalities and wealthiest women in America, can afford the bag.
"Switzerland chose not to stay neutral over the incident of perceived racism. Apparently it felt embarrassed and rightly so," said David Perecman, a civil rights violation lawyer in New York for over 30 years. "Racism is embarrassing and certainly does not go unnoticed."
The boutique owner also apologized to Oprah, reported the Chicago Sun-Times.
While Winfrey did not publically say that she was discriminated against, the reported incident has sparked a lot of debate on the Internet. While racial discrimination is wrong, attorneys at The Perecman Firm understand that it is a daily reality for many people.
"Erroneous perception sparked an international controversy. The incident was also a sad reminder that discrimination is alive and well," said Perecman.
"The store assistant deserved to lose what may have been a very big commission," he added.
The Chicago Sun-Times article cited is "Swiss tourism officials, boutique owner apologize to Oprah for purse debacle."
Individuals who believe they have been victims of a New York civil rights violation, including discrimination in the workplace or race profiling can contact The Perecman Firm at 212-977-7033.
Categories: Civil Rights


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The Fast & The Furious
Ratings System
Logo Evolution
Antaries
Strings and Horns: How John Williams Could Have Helped The DCEU
There's no denying it: John Williams is one of the greatest composers who ever lived. The fact that he's created more memorable movie tunes than almost anyone else alive or dead is testament to his power as a creator of thematic material, something I believe missing from many of today's blockbuster releases. Among his many graceful motifs, one of the most enduring is his themes for Richard Donner's 1978 film, Superman, the first big-screen, big-budget extravaganza that swept audiences away with the adventures of the Man Of Steel. The theme, reused for no fewer than four sequels (including Bryan Singer's Superman Returns, albeit seconded by composer-in-residence John Ottman, who reworked many of Williams' iconic elements into the new film) has become as synonymous with the character as the big S or Lex Luthor.
So when Zack Snyder announced that his reboot of DC Comics' on-screen franchise properties, beginning with 2013's Man Of Steel, would not reuse the classic themes, many fans felt dubious that replacement composer Hans Zimmer, who had worked wonders with Christopher Nolan's Dark Knight saga, would be able to achieve a similar memorable sound. After all, Zimmer's music tended to atmospheric, while Williams was definitely more melodic.
The end result of Man Of Steel, with Snyder's now lamentable grimdark aesthetic and the character's pummelling into melancholic oblivion by emotionally constipated moral and ethical contrivance, left as much to admire as it did to disappoint. Critics of the film cited the depressing nature of a "realistic" Superman inhabiting our increasingly darker world, while fans applauded the large-scale action, even if it lacked emotional weight. One of the elements rising above much of the controversy was Zimmer's score, a pulsating, moving, uplifting electronic-slash-percussive thing that fit the reboot's slash-and-burn modernism. Frankly, it's one of my favourite overall scores in recent years, and one I still listen to regularly.
But what if? What if Snyder had turned to John Williams to reprise his music and themes for the new Superman? It struck me that a quick re-edit of Snyder's action sequences set to the original Superman theme might give the film's sense of darker, muted heroism a more uplifting vibrancy: so I decided to test that theory out.
A quick search online will uncover many videos where people have combined Snyder's visuals with Williams' themes, to great success. Instead of cutting a "trailer", however, I've tried to keep three of the film's most memorable moments intact as where possible. They include the "First Flight" sequence (which, after Superman takes off, plays out without me cutting it at all), and several rescues of Lois Lane. What surprised me as I put this clip together is just how easily Snyder's edits themselves fit into Williams music (the track is lifted from Ottman's Superman Returns Soundtrack recording). The zooms, action beats, and musical cues are more-or-less as Snyder made them (with two exceptions, where I've judiciously cut brief moments out) and they highlight how easily Snyder could have dropped the Williams Score into the film.
This isn't to disparage Zimmer at all, because I think his score suits the mood Snyder was aiming at. With Williams' music in place, though, the film takes on an entirely different feel, I think you'll agree. Does it work better? That's for you to decide, naturally: one can only fantasise about the music Williams might have cooked up for Batman V Superman… or even Justice League.
Watch the Clip below, then continue the discussion after that!
https://www.youtube.com/watch?v=MR4Od8S0O08&feature=youtu.be
UPDATED!!! NOW WITH DANNY ELFMAN'S BATMAN THEME OVER BATMAN V SUPERMAN!!!
https://youtu.be/6H2Ex4VsKVU
Rodney Twelftree
If you're reading this, you've now learned that Rodney loves movies and will continue to write about them until he falls over dead. And even then he'll have some content scheduled post-mortem.
In Film - General, From the Editor
Grog the Ginger	July 26, 2016
It actually surprised me how perfect it went with Superman flying for the first time. That was spot on and such a great match I couldn't help but smile in the way the '78 Superman did. I didn't think it fit with the destruction at all though. I like in Red Letter Media's review they said shouting "9/11" at the "Superman!" bit of the music would be much more appropriate…
Rodney	July 26, 2016
LOL Yeah, RLM nailed that.
You're right about the destruction – I think Williams' themes suit the euphoric moments, such as "first flight" and the rescue sequences (saving Lois each time) but less so the outright destruction. It wouldn't surprise me if Snyder had temp-edited that first flight sequence to Williams score, because it fits superbly well. I guess 4/4 time works well with modern editing techniques? LOL
Kgothatjo Magolego	July 31, 2016
John Williams' score actually fits in perfectly with that moment where Superman first flies. I just had an enourmous wave of nostalgia hit me. I loved the score for Man of Steel but I had a friend point out to me that Zimmer returns to the same well a few too many times. I have to agree. He does the same in The Dark Knight Rises, feels like he's just playing one tune over and over again. A good tune though.
I don't think Elfman's score quite fits in with that action scene from Dawn of Justice. Feels like Elfman's score was made to coincide with Batman's punches – those awesome BAM! moments in the comics.
I agree, I don't think the Batman score suited BVS that well, it felt too *thin* if that's the right word to describe it. But Williams' Superman score is superb against Snyder's visuals (IMO, of course). The first flight sequence is note for note, beat for beat, untouched opposite the music, and to a frame it works brilliantly.
I get that Snyder wanted to distance his approach to the "classic" films starring Reeve, but I think the music, much like the Harry Potter or Star Wars themes, could interchange between characters/arcs and still have that instantly identifiable, almost unqualifiable emotional resonance.
If Snyder had any sense, he's sneak a small hint of the five-note melodic hook into Justice League for when Superman comes back to life. You know, because how cool would that be!
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Started off her year at the Cowboy Preview (Sept. 1), finishing fourth overall and second for the Razorbacks at 10:42.70… In her second meet, she finished fifth overall at the UC Riverside Invitational (Sept. 16) at 17:37.10, the fourth-best time for Arkansas.
Began her career as a Razorback at the Riverside Invitational (Sept. 17). She finished with a time of 18:27.10 over the 5K course, good enough for the sixth-best time for Arkansas and 28th overall … Improving her performance with a personal best of 17:39.50, she was able to finish as 33rd overall and 13th for the Razorbacks.
Redshirted her first year on campus.
Named two years to the All Arkansas Preps Track and Field Team … Won Arkansas Meet of Champs 3200 meters and 1600 meters … One of only three female Arkansas high school athletes to ever break five minutes in the mile … Two State T/F Titles: 1600 meters and 3200 meters … Helped Cabot Panthers to win a second place state title in track and field … Best cross country time: 18:51 at 2013 Footlocker South Regional … Three-time 7A Central Conference Cross County Champ … Holds school records in the 1600 meters and the 4X800-meter relay … Arkansas All-State Track and Field …. Arkansas All-Star Cross Country Team … Finished sixth at 2015 Texas Relays 1600m with 4.59.99 … Fastest Mile (St. Louis Festival of Miles): 4.59.86.
Born on June 28, 1996 … Daughter of Holly and Sandy Huckabee … Has an older sister, Marley and an older brother, Lance … Majoring in kinesiology … Plans on pursuing a career in physical therapy and or coaching upon completing her degree.


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Category: france
After 18 months — and recommended retractions — no movement in psychology case
The University of Rennes-2
"Dissatisfied." That's how Nick Brown and James Heathers describe their reaction to the progress — or lack thereof — in the case of Nicholas Guéguen, a psychology researcher whose work the two data sleuths have questioned.
Brown and Heathers first wrote about the case in 2017. In a new blog post, they write that the science integrity office at the University of Rennes-2, where Guéguen works, pulled punches in its investigation of its faculty member and in two reports it issued last year about the case. (Brown and Heathers, who has called himself a "data thug," had hoped to make available a preliminary report about the case last year but said the university discouraged them from doing so — a stance that, if true, we wouldn't find surprising given many institutions prefer to sit on reports of such investigations.)
Continue reading After 18 months — and recommended retractions — no movement in psychology case
Posted on May 9, 2019 May 9, 2019 Author Adam MarcusCategories france1 Comment on After 18 months — and recommended retractions — no movement in psychology case
"We were very uncomfortable with this situation:" French group loses aging paper for "overlap"
The authors of a 2017 paper on how chronic inflammation might hasten aging have retracted the work because it turned out to be a collage of previously published articles.
The paper, "Chronic Inflammation: Accelerator of Biological Aging," appeared in The Journals of Gerontology: Series A, an Oxford University Press title. It has been cited 41 times, earning it a "Highly Cited Paper" designation from Clarivate Analytics' Web of Science, meaning it has earned more citations than 99% of papers published in its field that year. The first author is Bertrand Fougère, of Université de Toulouse III Paul Sabatier and Tours University Hospital.
Here's the notice (which we've reformatted for readability): Continue reading "We were very uncomfortable with this situation:" French group loses aging paper for "overlap"
Posted on January 21, 2019 January 21, 2019 Author Adam MarcusCategories france, oxford university press2 Comments on "We were very uncomfortable with this situation:" French group loses aging paper for "overlap"
A critic with more than two dozen retractions can't seem to stop plagiarizing
A mysterious lit and film critic who built a significant portion of his career using the words of other scholars instead of writing his own appears to be attempting a second act.
Last year, Richard-Lawrence Etienne Barnett, who has lost more than two dozen papers for plagiarism, published a book called "The Adversarial Text," which appears to have a rather cozy relationship with four of his retracted articles. The apparent purloinment was first reported by Volker Schröder, a scholar of French and Italian at Princeton University who has been following the Barnett case for the better part of two decades.
In 2001, Schroeder found that
Continue reading A critic with more than two dozen retractions can't seem to stop plagiarizing
Posted on June 25, 2018 June 25, 2018 Author Adam MarcusCategories duplication retractions, franceLeave a comment on A critic with more than two dozen retractions can't seem to stop plagiarizing
Caught Our Notice: Voinnet co-author issues another correction
Title: AtsPLA2-α nuclear relocalization by the Arabidopsis transcription factor AtMYB30 leads to repression of the plant defense response
What Caught Our Attention: A previous collaborator with high-profile plant biologist Olivier Voinnet (who now has eight retractions) has issued an interesting correction to a 2010 PNAS paper. Susana Rivas is last author on the paper, the correction for which notes some images were duplicated, and others were "cropped and/or stretched to match the other blots." Rivas is currently a group leader at The Laboratory of Plant-Microbe Interactions (LIPM), "a combined INRA-CNRS Research Unit." Continue reading Caught Our Notice: Voinnet co-author issues another correction
Posted on March 16, 2018 March 15, 2018 Author Alison AbritisCategories caught our notice, corrections, france, image manipulation, NAS, New Phytologist, Plant biology, plos one, pnas retractions, the plant cell2 Comments on Caught Our Notice: Voinnet co-author issues another correction
Questions swirl around CNRS director's decision to step down early
Anne Peyroche
Today, a French council was set to confirm the new head of a prominent research institute, the National Center for Scientific Research (CNRS). But the appointee took the job a few days early, after the interim director stepped down last week — and the speculation about why she left hasn't stopped ever since.
An official announcement from the French Ministry of Higher Education, Research and Innovation, which runs the CNRS, said Anne Peyroche would be replaced by her expected successor, computer scientist Antoine Petit. Although there have been discussions about some of Peyroche's work on PubPeer (some of which the authors have responded to, assuaging at least one critic), the announcement provided no reason for the new timetable; a news story in Le Figaro cited health reasons.
A spokesperson for the CNRS told Retraction Watch:
Continue reading Questions swirl around CNRS director's decision to step down early
Posted on January 24, 2018 January 25, 2018 Author Alison McCookCategories france6 Comments on Questions swirl around CNRS director's decision to step down early
Paper retracted when co-author forgets he had published a figure before
A 2016 case study in Neurology exploring a "mystery case" has been retracted because four figures had already been published in a 2012 article.
The two papers have three authors in common, but according to the retraction notice, none could explain the duplicate publication. The notice states that Pierre Labauge, the corresponding author on the 2012 paper and the last author on the Neurology paper, said he "did not remember the first paper" when revising the recent one. Continue reading Paper retracted when co-author forgets he had published a figure before
Posted on December 27, 2017 December 26, 2017 Author Victoria SternCategories duplication retractions, france, freely available, image manipulation, neurology, neuroscience retractions, society journal retractions1 Comment on Paper retracted when co-author forgets he had published a figure before
Researcher discovers paper published by co-author in another journal
In February 2016, Albert Jambon received some puzzling news.
Several colleagues had alerted him to a paper, published online in late December 2015 in the Journal of African Earth Sciences (JAES), reporting the discovery of a rare mineral, which Jambon had been analyzing.
When Jambon read the paper, he realized it was a modified version of a paper he had been working on for almost eight years. Impatient, one of his co-authors, Ahmad Bilal, had published his own version of the manuscript and listed himself as the sole author.
Jambon, a professor at Pierre and Marie Curie University, believes that Bilal's paper plagiarized his manuscript, but Bilal disputes this allegation. Bilal–who works at Damascus University in Syria–says he couldn't wait any longer to publish the manuscript, so wrote "a completely new version." Since the authors couldn't resolve the authorship dispute, in August 2016, the journal issued a "temporary" expression of concern, alerting readers to the authorship concerns. Now, a year and a half later, a spokesperson for the publisher says it's going to be retracted.
Eight years is a long time to work on a paper.
Continue reading Researcher discovers paper published by co-author in another journal
Posted on September 25, 2017 April 2, 2018 Author Victoria SternCategories author objections, authorship issues, elsevier, france, geology, J African Earth Sciences, SyriaLeave a comment on Researcher discovers paper published by co-author in another journal
What should a journal do when a scientist who committed misconduct submits a new paper?
Chris Surridge
In December of last year, Chris Surridge found himself in a situation not uncommon to journal editors: A researcher who had been found to have committed misconduct had submitted a manuscript to the journal Surridge edits, Nature Plants. Retraction Watch readers may recall the name of the corresponding author, Patrice Dunoyer, who has had five papers retracted and five corrected following an investigation into work out of the Olivier Voinnet lab.
So what to do? The journal accepted the paper in May, and published it in June, along with a thoughtful editorial likening prizes and cheating in science to those phenomena in sports. The editors, according to the editorial, "treated the study we received as we would any other." We asked Surridge to answer a few questions about the episode.
Retraction Watch (RW): Was there some internal debate about whether to consider publishing a paper by Dr. Dunoyer? Did you personally hesitate? Why or why not? Continue reading What should a journal do when a scientist who committed misconduct submits a new paper?
Posted on August 24, 2017 September 15, 2017 Author Alison McCookCategories france, Nature Plants, nature publishing group, olivier voinnet, switzerland6 Comments on What should a journal do when a scientist who committed misconduct submits a new paper?
Authors retract two plant biology papers over duplicated images
Plant scientists have issued two retractions after noticing several images had been duplicated within and across the papers.
The papers both appeared in March 2002 in The Plant Cell and The Plant Journal.
The last author on both papers — Jonathan Jones, a professor and group leader at The Sainsbury Laboratory in Norwich, UK — took responsibility for the duplications. He told us:
As last author I was responsible for checking the papers but did not notice the similarities between figures in the different papers. I regret this and took action as soon as I realized there was an issue. Both papers went through peer review and the issue was not picked up at that point either.
Susana Rivas, the first author on both papers, has collaborated with beleaguered plant scientist Oliver Voinnet — and was a second author on one of his eight retractions (which we covered here).
The editor-in-chief of TPJ Christoph Benning said that, after the authors contacted them, the journals looked into the issue, confirmed the duplications and then retracted the papers: Continue reading Authors retract two plant biology papers over duplicated images
Posted on June 5, 2017 June 5, 2017 Author Victoria SternCategories duplication retractions, france, image manipulation, olivier voinnet, Plant biology, Plant Journal, society journal retractions, the plant cell, uk retractions, wiley, wiley retractionsLeave a comment on Authors retract two plant biology papers over duplicated images
Author objects to retraction after he says journal ignored his queries for three years
In 2014, a journal contacted researcher Denis Rousseau about one of his papers that had just been published online ahead of print, raising some concerns. According to Rousseau, he sent the journal a corrected figure "almost immediately," which he believed addressed the issue.
Rousseau, a cell biologist at the University Joseph Fourier in Grenoble, France, said he then contacted the journal many times over the next three years to ask about the status of the paper — which never ended up in print — but heard nothing back.
Three years passed.
In March, the publisher finally contacted Rousseau, this time to ask him to issue a formal retraction for the paper. And despite his objections, Molecular and Cellular Biology published a sparse retraction notice, which provides little information about what went wrong:
Continue reading Author objects to retraction after he says journal ignored his queries for three years
Posted on May 2, 2017 May 2, 2017 Author Victoria SternCategories diabetes, duplication retractions, france, freely available, hepatology, hepatology, image manipulation, molecular and cellular biology, molecular biology, society journal retractions, wiley, wiley retractions1 Comment on Author objects to retraction after he says journal ignored his queries for three years


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The Social Media Echo Chamber in the Post-Factual Age
November/December 2016 Issue
Brexit means Brexit," said new British Prime Minister Theresa May as she took office, keen to stress that her government will respect the outcome of the historic referendum. The nation is now in a kind of suspended animation—the U.K. is technically still a member of the European Union (EU) until the decision is taken to trigger Article 50 of the Treaty of Lisbon, which outlines the procedure for leaving the EU.
Once the Article 50 button is pressed, the U.K. will have 2 years to negotiate an exit deal—although a longer time frame is possible if all parties agree. May said that she won't trigger Article 50 before the end of the year. So, the U.K.'s Brexit ministers are no doubt working fiendishly behind the scenes to get to a grip on the task they have been charged with. In terms of the day-to-day lives of all U.K. citizens, little, if anything, seems to have changed—for now.
There is plenty to consider in the post-Brexit world for digital content: competition, data privacy, and taxation. The European Commission (EC) released a raft of proposals for copyright reform, which—according to Andrus Ansip, EC's VP for the digital single market—will "ensure that more content will be available, transforming Europe's copyright rules in light of a new digital reality. Europe's creative content should not be locked-up, but it should also be highly protected, in particular to improve the remuneration possibilities for our creators."
Content strategists may be wise to consider some uncomfortable questions about the role of social media during the referendum campaign. According to a survey conducted just before the nation went to the polls, 26% of people used social networks to share and receive information about the referendum in the run-up to polling day; 24% said that social media helped enhance their understanding of the issues connected with the referendum.
The outcome of the referendum was extremely close—52% voting for Leave and 48% for Remain—but this proximity masks strongly polarized voting patterns, breaking down along demographic lines. Young people were much more likely to vote Remain, while older people were more likely to vote Leave. Areas in which more residents had university degrees skewed sharply to Remain. The highest income areas all chose to Remain, while the lowest income areas voted to Leave. Metropolitan centers such as London were for Remain, while rural areas opted overwhelmingly for Leave.
Although many people said that social media was important to them as a source of information on the issues, I wonder how balanced a view this provided. It's reasonable to assume that most people's social media graph skews to their own demographic, whether by age, education level, region, or economic status—or perhaps all of these. The echo-chamber effect is likely to have been in full force, with most people only seeing self-reinforcing material in their timelines and possibly even search results.
During the campaign, claims from both sides were subjected to impartial, rigorous, and balanced assessment by Full Fact, the U.K.'s independent fact-checking charity. Full Fact is a small organization, but its profile was high during the campaign, with celebrities such as Andy Murray and J.K. Rowling praising its operation. Despite this, facts were in short supply prior to the vote.
It was always going to be difficult for the Remain side—with its rational appeals and economic arguments—to counter the fear, uncertainty, and doubt presented by the Leave camp, which increasingly focused on concerns around immigration. A week before voting day, marketing expert Mark Ritson noted that "[t]he Leave campaign is winning the all-important emotional argument on Brexit." In his view, the decision "will come down to … who can play the emotional advantages better than the other."
Whatever side of the argument someone was on, the votes have been cast, and the politicians must get on with delivering an outcome. The legal and regulatory framework that will eventually apply for content owners in the U.K. is yet to be determined—but for those using content to persuade and influence, the lessons learned from the bruising and rowdy political campaigns are clear to see.
The Nordic Way to Compelling Cross-Channel Content
All things Scandinavian are having a moment here in the U.K. Hardly a marketing campaign goes by without somehow shoehorning in the Danish concept of hygge, which the Oxford English Dictionary defines as "a quality of cosiness and comfortable conviviality that engenders a feeling of contentment or well-being (regarded as a defining characteristic of Danish culture)." It's a remarkably versatile marketing concept.


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What Is Constant Contact And How Does It Work
If you've been thinking about trying out Constant Contact, you've come to the right place. Constant Contact is an online marketing company with offices in Waltham, Massachusetts, Loveland, Colorado, and New York, and a website that lets you create, send, and manage email lists. With this in-depth review, you'll be better equipped to decide whether it's the right fit for you. Let's get started!
A few downsides to Constant Contact include its lack of automation features, like branching points and splits. It also doesn't offer personalized emails, like some email providers do. Workflows begin with a trigger, such as an email or a website visit. Depending on your needs, you can change the order of emails or add delays between them. Constant Contact offers integrations with third party applications like Vimeo. With this integration, you can create automated email workflows for events, sell digital products, and respond to abandoned shopping carts.
Constant Contact also allows you to create signup forms for every visitor to your website. Signup forms can be created with its easy-to-use interface, which makes it a breeze to copy and paste into your site. Constant Contact's signup forms can be tailored to the interests of your website visitors. Then, you're ready to launch your email campaign! Once you've established your list, you can begin sending targeted emails.
Constant Contact's ability to segment its contacts by tags is another great feature. You can send targeted email to people who match certain tags or interests in your business. Constant Contact offers detailed reporting as well. The best part? It's completely free to use. You can even sign up for a 60-day trial and try it for yourself! Make sure to check the free trial and learn about the pricing and features.
Constant Contact's email tools are affordable and simple to use. Even newbie email marketers can understand the platform's interface. The software promises high deliverability, which means less chances of emails getting caught in spam filters. It also offers niche-specific features such as Eventbrite and Google Analytics integrations. You can also use Constant Contact to integrate social media accounts, such as Facebook. You can also create Facebook ads and integrate campaigns.
Another great feature of Constant Contact is its email editor. It lets you send automated emails to new subscribers. You can also track the performance of your email. You can segment your contacts to send them special messages and offers. The Constant Contact email editor allows you to segment contacts. If you have a Shopify-based store, Constant Contact can help you amplify your efforts. Constant Contact syncs your products and contacts automatically, allowing for targeted emails and offers to customers. Constant Contact can help you recover customers and sales lost.
Constant Contact also offers intuitive marketing applications that help small businesses and nonprofits build email lists. Their applications include email marketing, social campaigns, and event marketing. Other useful features include reporting and survey management, and drag-and-drop email templates. This means Constant Contact can handle all of your email design and communication needs. Because Constant Contact offers customizable templates, it is also a great option for e-commerce merchants. Constant Contact is not as customizable for advanced creative designers.
Pricing depends on the size of your email list and how many you wish to send. There are two options: email Plus and email. The latter includes a range of additional features, including coupons, surveys, and registration forms. Constant Contact is priced fairly competitively in the market, but it falls behind Editors' Choice winner Campaigner. Constant Contact also offers a free trial plan that allows you to test it out and get started for less.
The Constant Contact Reporting tab provides a summary of the statistics for your email campaigns. To compare each email's performance with its competitors, you can filter the data by campaign name or time frame. You can also export this data to Excel and CSV. Constant Contact also has a mobile app. Those with large contact lists might want to opt-in to a monthly plan. If you don't require advanced features, this can be expensive.
Shared Mailbox Constant Contact
Constant Contact Gap


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Home Talk Todd Starnes
Rudy Giuliani: James Comey is a "Publicity Whore" with Questionable Morals
Rudy Guiliani spoke to Todd Starnes about why the $130,000 President Donald Trump reimbursed to his personal attorney Michael Cohen to pay Stormy Daniels was not a campaign finance violation. Additionally, Mr. Giuliani expressed his strong opinions on former FBI Director James Comey.
"I guess the Martha Stewart case would have given you an indication that he was a publicity whore, which he is," Giuliani said. He then added, "Then the whole thing he did with Ashcroft at his bedside, which was for the cameras. I think only somebody like a Clinton would appoint him; you know somebody who is, I won't say anything, but somebody who is, not looking for the most moral character, let's put it that way."
Click here to subscribe to Todd's daily podcast - one of the fastest-growing conservative podcasts in America!
Listen to the whole interview:
Jon Costantino
The Todd Starnes Show – September 30th, 2019
The Todd Starnes Show – September 23rd, 2019
Todd Starnes Show 10/02/19 First Hour
Hogan Gidley, Pastor Robert Jeffress, Kayleigh McEnany, College of the Ozarks, Anne Graham Lotz, Rep. Debbie Lesko


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Westman's Case
Document Cited authorities 16 Cited in 48 Precedent Map Related
Court Maine Supreme Court
Writing for the Court PHILBROOK, J.
Citation 106 A. 532
Parties WESTMAN'S CASE
106 A. 532
Supreme Judicial Court of Maine.
Appeal from Supreme Judicial Court, Cumberland County, at Law.
Proceeding for compensation under the Workmen's Compensation Act for death of Fred G. Westman, the employe, by Mabel C. Westman, his widow, against a towboat company and its insurer. Compensation was awarded, the award affirmed by the justice of the Supreme Court, and the employer and insurer appeal. Appeal dismissed.
Argued before CORNISH, C. J., and SPEAR, HANSON, PHILBROOK, and DEASY, JJ.
Frederic J. Laughlin, of Portland, for applicant.
H. S. Avery, of Boston, Mass., for defendant.
Carroll B. Skillin and Edward H. Wilson, both of Portland, for London Guarantee & Accident Co., Limited.
PHILBROOK, J. This is a proceeding instituted by the dependent widow of Fred G. Westman to recover compensation under the terms and conditions of the statute commonly known as the Workmen's Compensation Act.
At the time of his fatal accident the deceased was employed by the defendant towboat company as a cook on its towboat Portland. By the terms of his employment he performed all the duties of cook on the boat, had full authority to buy, and was charged with the duty of buying, all supplies necessary to that work, and, when required, assisted around the deck. The accident occurred at about noon, on the 16th day of February, 1918, when the Portland was lying in a dock. The boat was moored to a coal lighter, which, in turn, was moored to the wharf. Between these two crafts and the head of the dock was lying another lighter, which was also moored to the dock. This lighter was in charge of A. P. Bennett, a witness in the case. On the outside of the second lighter was moored another towboat, and outside the latter was moored still another towboat. The distance from the edge of the wharf to the surface of the water was estimated to be nine or ten feet. On the fatal day, having served dinner to the crew and partaken of his own midday meal, Westman went to a neighboring store to buy supplies. Taking two or three purchases under his arm, he started to return to the boat, being observed to pass along the dock toward his destination, and thus, for the last time, was seen alive. Mr. Bennett, who was on board his lighter, says he heard a thump thereon, followed by a splash. Upon making investigation he saw the unconscious body of Westman in the water between the ends of the two lighters, called for assistance, and the body was taken to the dock. Resuscitation was attempted, but without avail. Westman was dead.
Proper steps were taken to present the claim of the plaintiff to the chairman of the Industrial Accident Commission. He sustained the claim, and ordered payment of the compensation provided by statute. This finding and order, following the practice provided in such cases, was presented to a justice of the Supreme Court, who rendered a decree in accordance therewith, and from that decree the defendants bring the case before us by appeal.
Defendant's Contentions.
(1) That the deceased employe was a seaman on a vessel engaged in interstate and foreign commerce, and therefore his dependent widow is not entitled to the benefits of the Workmen's Compensation Act.
(2) That the burden of proof is upon the petitioner to show by the preponderance of the evidence that the injury arose out of and in the course of the employment, and that, failing to establish the burden of proof, the petitioner cannot recover.
(3) That there is no evidence on which the commissioner was warranted in finding as a fact that the injury arose out of, and in the course of, the employment; that such a finding of fact on the evidence presented could he mere conjecture only, and that the evidence most favorable to the plaintiff was as consistent with the injury arising in such a manner as not to be compensatable as to be in such a manner as to be compensatable.
First Contention.
As the basis of their first contention the defendants call attention to R. S. c. 50, § 1, par. 2, which provides that "masters of and seamen on vessels engaged in interstate or foreign commerce" are excluded from the classes of employes who are entitled to the benefits arising under the Compensation Act. The reasons for this statutory exclusion, evidently growing out of the maritime law and the jurisdiction of admiralty courts over maritime torts, are not in issue, so that a discussion of this most interesting subject would be without justification or merit at this time. Nor is the jurisdiction of the state tribunal over the instant case denied, a jurisdiction which the Judicial Code (Act Cong. March 3, 1911, c. 231, 36 Stat. 1160) § 256, as amended by Act of Congress October 6, 1917, c. 97, § 2, 40 Stat. 395 (U. S. Comp. St. 1918, § 1233), confers in behalf of those who claim "the rights and remedies under the workmen's compensation law of any state." But the defendants read the excluding clause literally, and thereunder claim immunity from liability. Therefore the first question presented to us is whether at the time of his fatal accident the deceased was a seaman on a vessel engaged in interstate or foreign commerce, under the terms of the Compensation Act, when properly construed. The record discloses that the towboat Portland, on which Westman was employed as we have stated, was duly registered at the proper United States customs house; that the range of her license was from Eastport to Cape Cod; that her towing duties consisted in going wherever her orders called her to go, within the range of her license; that the greater part of her work was in Portland harbor; that at the time of the accident she was not engaged on any job, but was lying at the dock.
Defendants contend that, under these conditions of registry, license, and breadth of duties, this towboat is to be regarded in general terms as a vessel engaged in interstate and foreign commerce. They even claim that her principal business was aiding and facilitating such commerce, although we cannot concede that the record substantiates this claim. They urge that the true question for determination is whether this vessel was one generally engaged in interstate and foreign commerce, and not whether she was so engaged at the time of the accident. They say that, without the more permanent classification as to the character of the vessel's employment, there would arise frequent confusion and uncertainty as to the rule applicable under the Compensation Act, because the employe might at one moment be engaged in interstate and foreign commerce and otherwise at another moment. According to the great weight of authority, however, the test must be applied to the conditions actually existing at the time when the accident occurred.
In N. Y. C. & H. R. R. Co. v. Carr, 238 U. S. 260, 35 Sup. Ct. 780, 59 L. Ed. 1298, Mr. Justice Lamar said:
"Owing to the fact that during the same day railroad employees often and rapidly pass from one class of employment to another, the courts are constantly called upon to decide those close questions, where it is difficult to define the line which divides the state from interstate business. * * * Each case must be decided in the light of the particular facts with a view of determining whether at the time of the injury the employe is engaged in interstate business, or in an act which is so directly and immediately connected with such business as substantially to form a part or a necessary incident thereof."
This opinion, it should be observed, was given in an action brought under the Federal Employers' Liability Act, and not under a Workmen's Compensation Act; but we hold that the same rule should apply to actions brought under either act. Other cases in which the same rule is applied are Shanks v. Delaware, Lackawanna & Western Railroad, 239 U. S. 556, 36 Sup. Ct. 188, 60 L. Ed. 436, L. R. A. 1916C, 797; Erie Railroad Co. v. Jacobus, 221 Fed. 335, 137 C. C. A. 151; Illinois Central R. R. Co. v. Behrens, 233 U. S. 473, 34 Sup. Ct. 646, 58 L. Ed. 1051, and cases cited in Ann. Cas. 1914C, 163.
In Morrison v. Commercial Towboat Co., 227 Mass. 237, 116 N. E. 499, a case arising under the Massachusetts Workmen's Compensation Act, the court was considering the claim of a master of a towboat, and discussed the same excluding clause as that now before us. In that case sometimes the boat was engaged in towing barges from Boston docks to a point down the harbor where ocean-going tugs took them and towed them to ports in other states. Sometimes the boat was employed in work wholly within the harbor, and
in no way connected with or similar to that just above described. When engaged in moving barges as the initial part of their interstate voyage the court held that the exclusion of the statute applied, but further said:
"As the towboat on which the plaintiff was master plied only within the limits of Boston Harbor, it may be assumed that at times it was engaged in work that plainly was of intrastate character. The decisive question in this case is, was the towboat Hersey engaged in...
Hinds v. John Hancock Mut. Life Ins. Co.
Supreme Judicial Court of Maine (US)
...then the injury has resulted through accidental means.' This case and its definition were approved in Westman's Case, 118 Me. 133, 141, 106 A. 532. Whatever the thought processes of the decedent may have been when he placed a loaded revolver at right angles against his temple and pulled the......
Gilbert v. Maheux
...for compensation purposes, both prerequisites for the recovery of benefits under the Act would be satisfied. Westman's Case, 118 Me. 133, 106 A. 532 (1919); Paulauskis' Case, 126 Me. 32, 34, 135 A. 824 (1927); Brown v. Palmer Construction Company, Inc., Me., 295 A.2d 263 (1972); Barrett v. ......
Boyce's Case
...is doing what he might reasonably do and at a place where he might reasonably be, it is compensable. See Westman's Case, 118 Me. 133, 106 A. 532, where cook of towboat went from boat at dock to a store for supplies and on return was drowned, and it was held that the injury was traceable to ......
Sullivan's Case
...connection between the conditions under which the employee worked and the injury which he received, Westman's Case, 118 Me. 133, 143, 106 A. 532; that the injury must have been due to a risk "because employed." Mailman's Case, 118 Me. 172, 180, 106 A. 606, 610; Gray's Case, 123 Me. 88, 121 ......


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Pan Shaoqing () (ur. ?, zm. 5 lutego 1983) – chiński duchowny rzymskokatolicki, a następnie Patriotycznego Stowarzyszenia Katolików Chińskich, antybiskup Xiwanzi (biskup Zhangjiakou).

Biografia
W 1958 został antybiskupem Xiwanzi. 20 kwietnia 1958 w Xianxianie przyjął bez zgody papieża sakrę biskupią z rąk biskupa Xianxianu Francisa Xaviera Zhao Zhenshenga SI, zaciągając tym samym na siebie ekskomunikę latae sententiae. Legalny, mianowany przez papieża biskup Xiwanzi Melchior Zhang Kexing żył przez cały okres rządów bpa Pana Shaoqinga i nigdy nie został odwołany z tej katedry.

Od 1980 Pan Shaoqing nosił tytuł biskupa utworzonej przez Patriotyczne Stowarzyszenie Katolików Chińskich diecezji Zhangjiakou

Uwagi

Przypisy

Bibliografia

Chińscy biskupi katoliccy
Zmarli w 1983


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Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is the most common undifferentiated ovarian malignancy in women under 40 years of age. We sequenced the exomes of six individuals from three families with SCCOHT. After discovering segregating deleterious germline mutations in SMARCA4 in all three families, we tested DNA from a fourth affected family, which also carried a segregating SMARCA4 germline mutation. All the familial tumors sequenced harbored either a somatic mutation or loss of the wild-type allele. Immunohistochemical analysis of these cases and additional familial and non-familial cases showed loss of SMARCA4 (BRG1) protein in 38 of 40 tumors overall. Sequencing of cases with available DNA identified at least one germline or somatic deleterious SMARCA4 mutation in 30 of 32 cases. Additionally, the SCCOHT cell line BIN-67 had biallelic deleterious mutations in SMARCA4. Our findings identify alterations in SMARCA4 as the major cause of SCCOHT, which could lead to improvements in genetic counseling and new treatment approaches.


Needle Exchange » Happy Canada Day Everyone! Honk if you're Canadian!
Happy Canada Day Everyone! Honk if you're Canadian!
Maple Leaf via Pure Nintendo.
Honk via the comments below.
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