text:
Nickelodeon UK To Launch Slime Across the UK
From Broadcastnow.co.uk:
Nick launches Slime tour
Nickelodeon is set to launch a new interactive roadshow programme to coincide with its live summer tour. Slime Across the UK will be hosted on the road by Ugly Mark [Mark Felgate] and Laura Hamilton.
Nickelodeon USA recently completed a similar tour called Slime Across America, where Nickelodeon USA presenter Pick Boy toured the USA driving a 18-wheel Slime Mobile.
Posted at 3:44 AM Links to this post
Nickelodeon UK's, Nicktoons, Nick Jr. Channel's and Nick Jr. 2's June 2007 Highlights
According to the Sky Ventures website, here are Nickelodeon UK's, Nicktoons, Nick Jr. Channel's and Nick Jr. 2's June 2007 highlights:
Highlights on Nickelodeon
NICK HEADS
Nickelodeon's BAFTA Craft 2007 "Best New Media" team is thrilled to be premiering the return of interactive quiz show "Nick Heads" this June.
Watch Ugly Mark and Laura Hamilton, galloping the length and breadth of the UK in search of Britain's ultimate Nickelodeon fan - in the UK's most exciting afternoon daily TV event. "Nickelodeon's Nick Heads".
"Nick Heads" is the UK's biggest daily fully integrated on-TV, online and via red-button kids TV show. A Nick Head is someone who knows ALL there is to know about Nickelodeon - the ULTIMATE Nick fan. One viewer a day is going to be crowned it, but they'll need to muster all their cunning skills and knowledge to prove this.
Join Ugly Mark and Laura in their search for the ultimate "Nick Heads", including challenges like the longest, biggest Burp Off and Mestermind - where every correct answer wins an exciting prize and leads their opponent to a sliming.
Nickelodeon is all about fun, so we've made sure that EVERY viewer can interact and take part. When watching and shouting the answers at your telly isn't enough, viewers can take control from the comfort of their home by answering live questions about their favourite Nickelodeon shows via red button and at www.nick.co.uk/nickheads
Weekdays @ 4pm
NAKED BROTHERS BAND
The massive US series about the most famous band you've never heard of, is here! In the US, Naked Brothers Band recently achieved the biggest series debut in Nickelodeon's 27-year history.
Brand new Naked Brothers Band tells the exciting story of brothers Nat and Alex, who are catapulted to international fame and fortune when the band they create at school becomes a global smash. Much like the group and its music, the TV series is also a runaway success.
Band leaders Nat and Alex (played by real-life siblings) Nat and Alex Wollf) embark on the thrilling adventure of soaring success and stardom with school friends and fellow band mates Thomas, David, Qaasim and Rosalina.
Filmed in a documentary style, Naked Brothers Band is a fly-on-the-wall glimpse into the lives of school kids who've suddenly become megastars. The series charts their fame, friendships, squabbles and adolescent experiences.
As well as playing their roles, Nat and Alex also write and perform the original songs in the show, which were created, written and directed by their real-life mother, actress Polly Draper, and co stars their father, jazz musician Michael Wollf.
Premiering 5 June
Tuesdays and Thursdays @ 4.30pm
MR MEATY
Premiering this June only on Nickelodeon, a hilarious new puppetry series called "Mr Meaty".
From behind the counter of the "Mr Meaty" cafe, Josh Redgrove and Parker Dinkelman are two teenagers launching big plans to improve their lives and escape the monotony of minimum wage.
Whether it is Josh making a play for one of the "ladies", Parker geeking out at the arcade or the two of them plotting to make their breakthrough sci-fi/horror classic movie, "Ninja Zombies", you can be sure that this cafe is funnier and definitely more bizarre, than any local cafe you've been in before!
Premieres Saturday 9 June
Weekends @ 8.30am and 6.30pm
You can also join in at www.nick.co.uk
PET ALIEN
Premiering 4 June, tune in for a brand new animated series called "Pet Alien".
Meet 13 year old Tommy Cadle, who lives not so peacefully with five aliens in a lighthouse in the fictional town of DeSpray Bay.
"Pet Alien" follows Tommy's hectic life with five aliens named Dinko, Gumpers, Flip, Swanky and Scruffy from the planet Conforma.
Unlike most animated aliens living on Earth, the aliens in this cartoon don't wear disguises, luckily all the humans, except Tommy, are too clueless to tell that they're aliens.
You can also check out www.nicktoons.co.uk
Highlights on Nick Jr.
ROARY THE RACING CAR
NETWORK PREMIER - Ready, set...go! Meet Roary the Racing Car, the no. 1 star of a thrilling new preschool series from the makers of Fifi and the Flowertots!
The colourful, high octane show follows the adventures of Roary, a cheeky and energetic single-seater and his friends, at the amazing Silver Hatch race track. Produced using a combination of stop-frame and CGI animation, the show truly captures the speed and excitement of a Formula 1 race track in this turbo-charged show.
Listen out for the UK's top comic Peter Kay as the voice of Roary's friend Big Chris, plus racing legend Sir Stirling Moss, who narrates the series. Peter Kay also sings the catch theme tune and each episode features an original song performed by the characters.
Weekends @ 4pm
BUBBLE AND SQUEAK
Bubble and Squeak is an original UK show from Nick Jr. It joins Bubble the wizard and Squeak the frog as they present stories, songs and magical cookery fun for preschoolers!
From their home in a giant carrot rocket with their friends Matilda the magical book and Muffet the spider, Bubble and Squeak create "foody magic" every day by whisking up delicious healthy treats.
Whenever there is a problem, Bubble tries to help with one of his "trusty" magic spells, but they always end up going wrong! Instead, it's down to Matilda to tell a story to inspire a solution.
Bubble stirs up his magic cauldron to produce a recipe featuring today's magic ingredient - which could be anything from tomato to carrots or honey - and Squeak takes us to visit some children and find out some fascinating facts about the ingredient of the day.
After singing their favourite sing-along song, "The Magic of Food" Bubble and Squeak wash their hands and prepare the recipe, which could be anything from Pizza Clowns to See In The Dark Soup or Bumble Bee Flapjacks. Matilda takes them through the recipe in easy-to-follow stages that everyone can understand.
Once it's finished, it's time to clean up and tuck in. The dish of the day is scrumptious! But has it helped solve their problem? You'll have to wait and see....!
With behind-the-scenes nutritional advice from Fiona Hamilton-Fairley of the Kids' Cookery School in London and lots of magical special effects, Bubble and Squeak make healthy food fun for little ones!
Weekdays @ 12.30pm on Nick Jr
Every day @ 3pm on Nick Jr 2
CHIGLEY
Brand new to Nick Jr Classics - Chigley was the final series of the well-loved Trumptonshire trilogy of shows, following Trumpton and Camberwick Green. It joins Nick Jr Classics, Nick Jr's daily evening line-up of favourite children's shows from the 60s, 70s and 80s.
The show ws produced in the UK in 1969 using stop-motion animation and was voiced by children's TV legend Brian Cant, who also performed all the songs.
The action takes place in the village community of Chigley, near Camberwick Green in Trumptonshire. The characters include Mr. Swallow of Treddie's Wharf; Mr Cresswell, owner of Cresswell's Chigley biscuit factory; Harry Farthing the potter and his daughter Winnie and last but not least Lord Belborough of Winkstead Hall and his butler Brackett.
The show also features guest appearances by characters from the previous two series, including Windy Miller of Camberwick Green and the Trumpton Fire Brigade with their famous roll call.
Exclusive to Nick Jr daily @ 8.40pm
You can also join in at www.nickjr.co.uk
Nickelodeon UK's, Nicktoons, Nick Jr. Channel's an...


text:
package com.ilivoo.ch14.ch5.lock.pac.lock;

public class Producer implements Runnable{
	private PAC pac;

	public Producer(PAC pac){
		this.pac = pac;
	}

	@Override
	public void run() {
		while(true){
			try {
				pac.produce();
			} catch (InterruptedException e) {
				e.printStackTrace();
			}
		}
	}
}

redpajama_set_name: RedPajamaGithub


£1000 per pair. Available March.
May have to cut one speaker conductor shorter than the other to have the cable hang down straight.
Hope this doesn't cause undue anxiety to potential users.
Certainly worth keeping an eye on.
Interesting that this is another 'grille-less' design.
As per my Spendor A2's.
Maybe this is a trend.
I can see some people missing the grilles.
I haven't missed them for a second.
Makes me think, anyone tried to centre speakers in a stereo setup? Should it work?
+1.... often named so as an LCR (left center right) speaker.
Not really a chicken or a man named Robert, surprised?
Reports are the MA Studio's are very, very fussy about placement and room acoustics... as many studio monitors should be, perhaps. That being said, their marketing shows these in living rooms and as TV front channels.


text:
elodie-meheust » Hip hop » Lecrae - Church Clothes
Lecrae - Church Clothes album download
Lecrae 2013
Performer: Lecrae
Title: Church Clothes
Format: MP3 FLAC MP4 MOD RA MIDI MP4 MPC XM
Album Church Clothes. Church Clothes Lyrics. Yeah, uh One time for H-Town One time for D-Town One time for A-Town, M-Town. to Dr. King I ain't tryna' hate on my own kind But Al and Jesse don't speak for me I'm probably gon' catch some flack man But I'm-a swallow this pill like Pacman Some of these folks won't tell the truth Too busy tryna get them racks.
Church Clothes 2, officially Church Clothes, Vol. 2, is the second mixtape by Christian hip hop artist Lecrae, released on November 7, 2013 by Reach Records. Hosted by Don Cannon, it follows Lecrae's previous mixtape, Church Clothes, and Grammy Award-winning full-length album Gravity, both of which came out in 2012
Church Clothes 3 is the third mixtape by Christian hip hop recording artist Lecrae. It was released on January 15, 2016, through his label Reach Records. The mixtape is the third in his Church Clothes series, and his first major release since his studio album Anomaly. It features guest appearances from E-40, N'dambi, Propaganda, John Givez, JGivens, Jackie Hill-Perry, and label-mate KB. While the previous two mixtapes were hosted by DJ Don Cannon, on Church Clothes 3 S1 served as executive producer on the tape.
Lecrae - Church Clothes. Ashish Rajendra Masih. Lecrae - Don't Waste Your Life.
New mixtape from Lecrae. The mixtape "Church Clothes" is hosted by Don Cannon. Follow on twitter ae annon. PB ft Thi'sl (Prod by Charlie Heat Sarah J). hurch Clothes (Prod by Wit). old World ft Tasha Catour (Prod by Street Symphony). elcome to H-Town ft Tedashii & Dre Murray (Prod By Wit). nspiration (Prod by Wit). ise (Prod by 9th Wonder). arkest Hour ft No Malice (Prod by ThaInnaCircle). lack Rose (Prod by Tyshane).
Church Clothes 3 is the third mixtape by Christian hip hop recording artist Lecrae. The mixtape is the third in his Church Clothes series, and his first major release since his studio album Anomaly (2014).
Freedom (featuring N'Dambi). Gangland (featuring Propaganda). It Is What It Is. Can't Do You (featuring E-40). Misconceptions 3 (featuring Jackie Hill-Perry, John Givez and JGivens).
Lecrae - Church Clothes (EP) (2012). 2. Lecrae - Cold World. 3. Lecrae - No Regrets. Propaganda, Beautiful Eulogy, DJ Efechto - Misconception. More songs by Lecrae. HotLecrae - Church Clothes 3 (2016) 9 months Rap. HotLecrae - Church Clothes 2 (2013) 9 months Rap. HotLecrae - Anomaly (2014) 9 months Rap. HotLecrae - All Things Work Together (re-upload) 9 months Rap.
1 APB
Featuring [Ft] – Thi'slProducer [Prod By] – Charlie Heat, Sarah J
2 Cold World
Featuring [Ft] – Tasha CatourProducer [Prod By] – Street Symphony
3 No Regrets
Featuring [Ft] – Suzy RockProducer [Prod By] – Big Juice, Street Symphony
Featuring [Ft] – Lester L2 ShawProducer [Prod By] – Thainnacircle
5 Misconception
Featuring [Ft] – Beautiful Eulogy, DJ Efechto, Propaganda Producer [Prod By] – Courtland Urbano
6 Spazz
Producer [Prod By] – Charlie Heat, Sarah J
7 Rejects
Featuring [Ft] – Christon GrayProducer [Prod By] – Tha Kracken!*
Copyright (c) – Reach Records, LLC
Phonographic Copyright (p) – Reach Records, LLC
Manufactured By – Infinity Music Distribution
Distributed By – Infinity Music Distribution
Printed By – Infinity Music Distribution
Pressed By – The ADS Group
A&R – Torrance "Street Symphony" Esmond*
Barcode (String): 814509010916
Matrix / Runout: ['the ADS group' logo] 8740-CD-0007 13-187-23
Mastering SID Code: IFPI LK13
Mould SID Code: IFPI L820
none Lecrae Hosted By Don Cannon Lecrae Hosted By Don Cannon - Church Clothes (18xFile, MP3, Mixtape, 320) Reach Records none 2012
Related to Lecrae - Church Clothes
Tommy Tee - Tee Prod. Instrumentals Vol.3 album mp3
Infinity - "Infinity" Infinity album mp3
Criminal Mindz Prod. - Can can album mp3
Solar & Białas - Odliczanie Mixtape album mp3
The Producer - Arabic album mp3
EGreen - Entropia EP album mp3
DWM Prod - Love, Beats And Midnight People's Theory album mp3
Língua Nativa - Língua Nativa album mp3
Ravi - Masses album mp3
Mnero - Zwischen Tür Und Kopf album mp3

redpajama_set_name: RedPajamaCommonCrawl


I ended up getting the 5'10". Only have had one chance to use it. Bad thing was it was really windy so I stayed in shore break so I was not in the big surf. It worked great. I never once sank while on the wave. Looking forward to more time on the board.


Mission: develop a viable framework for strengthening dialogue and partnership between member-countries as well as with foreign governmental, non-governmental and international organizations for the development, approval and implementation of regional project activities that are supported by and serve the interests of all member states.
Vision: promote to improvement of life conditions of the peoples of Central Asia.
Strategy: EC IFAS developed the Plan of activities for effective elaboration, endorsement and implementation of the ASB Program and improvement of the political platform linking the national, regional and international institutions for the joint and coordinated work. In order to successfully implement the ASBP-3 projects, the capacities of EC IFAS and other IFAS bodies need to be strengthened. Our activities are aimed at setting a close link between the ASBP-3 and the process of improving institutional and legal framework.
Key activities: IWRM; sustainable development.
Partners: The Governments of Central Asian countries; GEF; UNECE; GIZ; WB Group; USAID; Swiss Agency for Development and Cooperation (SDC); EU; OSCE; UN Regional Centre for Preventive Diplomacy for CA; CAREC; UNDP; FAO; UNESCO: etc.


text:
import {inject, async, addProviders} from '@angular/core/testing';

import {TestComponentBuilder} from '@angular/compiler/testing';

import {Component} from '@angular/core';

import {NgbRating} from './rating';

function getAriaState(compiled) {
  const stars = getStars(compiled, '.sr-only');
  let state = [];
  for (let i = 0, l = stars.length; i < l; i++) {
    state.push((stars[i].textContent === '(*)' && stars[i].textContent !== '( )'));
  }
  return state;
}

function getStar(compiled, num: number) {
  return getStars(compiled)[num - 1];
}

function getStars(element, selector = 'span > span:not(.sr-only)') {
  return element.querySelectorAll(selector);
}

function getState(compiled) {
  const stars = getStars(compiled);
  let state = [];
  for (let i = 0, l = stars.length; i < l; i++) {
    state.push((stars[i].textContent === String.fromCharCode(9733)));
  }
  return state;
}

describe('ngb-rating', () => {
  it('should show 10 stars by default', async(inject([TestComponentBuilder], (tcb) => {
       tcb.createAsync(NgbRating).then((fixture) => {
         fixture.detectChanges();

         const compiled = fixture.nativeElement;

         const stars = getStars(compiled);
         expect(stars.length).toBe(10);
       });
     })));

  it('should change the num of stars with `max`', async(inject([TestComponentBuilder], (tcb) => {
       const html = '<ngb-rating max="3"></ngb-rating>';

       return tcb.overrideTemplate(TestComponent, html).createAsync(TestComponent).then((fixture) => {
         fixture.detectChanges();

         const compiled = fixture.nativeElement;

         const stars = getStars(compiled);
         expect(stars.length).toBe(3);
       });
     })));

  it('initializes the default star icons as selected', async(inject([TestComponentBuilder], (tcb) => {
       const html = '<ngb-rating rate="3" max="5"></ngb-rating>';

       return tcb.overrideTemplate(TestComponent, html).createAsync(TestComponent).then((fixture) => {
         fixture.detectChanges();

         const compiled = fixture.nativeElement;

         expect(getState(compiled)).toEqual([true, true, true, false, false]);
       });
     })));

  it('handles correctly the click event', async(inject([TestComponentBuilder], (tcb) => {
       const html = '<ngb-rating rate="3" max="5"></ngb-rating>';

       return tcb.overrideTemplate(TestComponent, html).createAsync(TestComponent).then((fixture) => {
         fixture.detectChanges();

         const compiled = fixture.nativeElement;

         getStar(compiled, 2).click();
         fixture.detectChanges();
         expect(getState(compiled)).toEqual([true, true, false, false, false]);
       });
     })));

  describe('aria support', () => {
    it('contains aria-valuemax with the number of stars', async(inject([TestComponentBuilder], (tcb) => {
         const html = '<ngb-rating [max]="max"></ngb-rating>';

         return tcb.overrideTemplate(TestComponent, html).createAsync(TestComponent).then((fixture) => {
           fixture.detectChanges();

           const compiled = fixture.nativeElement;

           expect(compiled.querySelector('span').getAttribute('aria-valuemax')).toBe('10');
         });
       })));

    it('contains a hidden span for each star for screenreaders', async(inject([TestComponentBuilder], (tcb) => {
         const html = '<ngb-rating max="5"></ngb-rating>';

         return tcb.overrideTemplate(TestComponent, html).createAsync(TestComponent).then((fixture) => {
           fixture.detectChanges();

           let compiled = fixture.nativeElement;
           let hiddenStars = getStars(compiled, '.sr-only');
           expect(hiddenStars.length).toBe(5);
         });
       })));

    it('initializes populates the current rate for screenreaders', async(inject([TestComponentBuilder], (tcb) => {
         const html = '<ngb-rating rate="3" max="5"></ngb-rating>';

         return tcb.overrideTemplate(TestComponent, html).createAsync(TestComponent).then((fixture) => {
           fixture.detectChanges();

           const compiled = fixture.nativeElement;

           expect(getAriaState(compiled)).toEqual([true, true, true, false, false]);
         });
       })));

    it('contains aria-valuenow with the current rate', async(inject([TestComponentBuilder], (tcb) => {
         const html = '<ngb-rating [max]="max" rate="3"></ngb-rating>';

         return tcb.overrideTemplate(TestComponent, html).createAsync(TestComponent).then((fixture) => {
           fixture.detectChanges();

           const compiled = fixture.nativeElement;

           expect(compiled.querySelector('span').getAttribute('aria-valuenow')).toBe('3');
         });
       })));

    it('updates aria-valuenow when the rate changes', async(inject([TestComponentBuilder], (tcb) => {
         const html = '<ngb-rating [max]="max" rate="3"></ngb-rating>';

         return tcb.overrideTemplate(TestComponent, html).createAsync(TestComponent).then((fixture) => {
           fixture.detectChanges();

           const compiled = fixture.nativeElement;

           getStar(compiled, 7).click();
           fixture.detectChanges();

           expect(compiled.querySelector('span').getAttribute('aria-valuenow')).toBe('7');
         });
       })));
  });
});

@Component({selector: 'test-cmp', directives: [NgbRating], template: ''})
class TestComponent {
  max: number = 10;
}


text:
Q: how to overlap two columns in css The below picture represents a timeline. Here the task "Exercise" starts from 8:00 to 8:15 and which has been marked with light-blue background color. The other two tasks - first one is "Travel to work" and second one is "Plan day" - are getting overlapped because the former task ("Travel to work") starts from 8:25 to 8:55 and the later task ("Plan day") starts from 8:30 to 9:00. So the overlapping tasks should show as given in the picture.
I tried to implement this using HTML table and css but I am really stuck to move further and its not working the way it is showing in the picture.

            8:00
            Excercise

            8:30
            Travel to work

            9:00
            Plan day

            9:30
            Review yesterday's comments

A: You could use CSS Flexbox and some manipulation of position to overlap tasks occurring in the same hour. This is a good start to achieving a similar layout to the image you provided.

.line{
    /* width: 100%;         */
    border-top: 1px solid black;
    /* position: absolute; */
    background-color: #ADD8E6;
    width: 100%;
    height: 30pt;
}
.title{
    font-size: 10px;
}

.time{
    border-top: 1px solid black;
    width: 49px;
    width: auto;
    height: 30pt;
    color: #555;
}

table tr {
  display: flex;
  align-items: center;
}

table tr td {
 flex: initial;
}

table tr td:not(:first-child) {
   border-left: .19rem solid blue;
}

table .overlap {
   margin-top: .75rem;
}

table .overlap td {
  height: 3rem;
  margin-bottom: -7px;
}

table .overlap > .time {
  padding-right: .6rem;
}

table .overlap .line:last-child {
  position: relative;
  left: -.5px;
  bottom: -2px;
}

.hour {
 font-size: 1.3rem;
 }

            8:00
            Excercise

            8:30
            Plan day
            Travel to work

            9:00
            Review yesterday's comments

redpajama_set_name: RedPajamaStackExchange


Biol Blood Marrow Transplant. 2015 Aug;21(8):1392-8. doi: 10.1016/j.bbmt.2015.05.001. Epub 2015 May 15.
Complement-Binding Donor-Specific Anti-HLA Antibodies and Risk of Primary Graft Failure in Hematopoietic Stem Cell Transplantation.
Ciurea SO1, Thall PF2, Milton DR2, Barnes TH3, Kongtim P4, Carmazzi Y3, López AA3, Yap DY3, Popat U4, Rondon G4, Lichtiger B3, Aung F3, Afshar-Kharghan V5, Ma Q4, Fernández-Viña M6, Champlin RE4, Cao K3.
Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address: sciurea@mdanderson.org.
Department of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Department of Benign Hematology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Department of Pathology, Stanford University, Palo Alto, California.
Detection of donor-specific anti-HLA antibodies (DSA) has been associated with graft rejection in all forms of transplantation. The mechanism by which DSA increase the risk of graft failure remains unclear. We hypothesized that complement-binding DSA are associated with engraftment failure in hematopoietic stem cell transplantation (HSCT) and analyzed 122 haploidentical transplant recipients tested prospectively for DSA. Retrospective analysis to detect C1q binding DSA (C1q+DSA) was performed on 22 allosensitized recipients. Twenty-two of 122 patients (18%) had DSA, 19 of which were women (86%). Seven patients with DSA (32%) rejected the graft. Median DSA level at transplant for patients who failed to engraft was 10,055 mean fluorescence intensity (MFI) versus 2065 MFI for those who engrafted (P = .007). Nine patients with DSA were C1q positive in the initial samples with median DSA levels of 15,279 MFI (range, 1554 to 28,615), compared with 7 C1q-negative patients with median DSA levels of 2471 MFI (range, 665 to 12,254) (P = .016). Of 9 patients who were C1q positive in the initial samples, 5 patients remained C1q positive at time of transplant (all with high DSA levels [median, 15,279; range, 6487 to 22,944]) and experienced engraftment failure, whereas 4 patients became C1q negative pretransplant and all engrafted the donor cells (P = .008). In conclusion, patients with high DSA levels (>5000 MFI) and complement-binding DSA antibodies (C1q positive) appear to be at much higher risk of primary graft failure. The presence of C1q+DSA should be assessed in allosensitized patients before HSCT. Reduction of C1q+DSA levels might prevent engraftment failure in HSCT.
Time to engraftment was assessed by DSA status () as well as by DSA level (). The median time to engraftment for all patients was 18 days. A significant difference in time to engraftment was noted for DSA status (p=0.004). Although the difference in median time to engraftment for DSA positive patients compared with DSA negative patients was very small (19 days versus 18 days), the percentage of patients experiencing engraftment was lower for DSA positive patients (68%) compared with DSA negative patients (96%). Within the allosensitized patients, the median time to engraftment for those with DSA levels ≤ 5,000 MFI was 16 days, however, for patients with DSA levels > 5,000 MFI, the median time to engraftment was not reached since less than 50% of those patients engrafted.
Biol Blood Marrow Transplant. ;21(8):1392-1398.
OS was assessed by DSA and C1q combined status (data not shown), GF status (using a landmark analysis, ), and by treatment group for patients with DSA (). The median OS one month post-transplant for patients who experienced GF was shorter compared with those who did not experience GF (5.3 months vs. 17.1 months). Finally, median OS for DSA patients who did not receive treatment was 5.3 months compared with 8.9 months for DSA patients receiving desensitization alone, and 13.4 months for patients receiving desensitization plus buffy coat.
This is the first study to examine the association between complement-binding DSA and risk of primary GF in patients with HSCT. We observed significantly higher probability of graft failure in patients with higher DSA levels and C1q positivity ( and ), and this effect also was seen in the subgroup of 17 T-cell replete haploidentical transplant patients. Our results indicate that 1) Presence of a positive C1q assay is associated with engraftment failure in patients with higher DSA; and 2) The goal of treatment should be clearing of the complement fixing antibodies before infusion of stem cells. A positive C1q assay was significantly associated with highly allosensitized patients (high DSA levels) suggesting that activation of the complement pathway likely causes apoptosis of hematopoietic progenitor cells.() Although the number of patients with complement-binding DSA was relatively small, the high risk of GF seen in patients who had high DSA levels and were C1q positive, suggest that this is a very high risk condition which should be avoided. Upfront testing of C1q in patients with DSA is necessary, as our data suggests that clearance of C1q is needed to obtain engraftment of donor cells. A two-step cost effective approach may be to screen for DSA patients with mismatched transplants and test for C1q patients who are allosensitized. Half of the patients with high DSA levels (> 5,000 MFI) tested negative for C1q and their risk for rejection was much lower. In fact only one patient in this category rejected the graft (MFI 6,265.78). It remains unclear if complement pathway gets activated in these patients or not and future studies will attempt to elucidate this aspect.
As shown by , the distributions of numerical DSA value in the C1Q+ and C1Q- patients were very different, with on average much higher DSA values in the C1Q+ patients. Due to this strong association between DSA and C1Q status, to assess effects of these variables and other patient covariates on the probability of GF, Prob(GF), a Bayesian logistic regression model was fit including terms for DSA within each C1Q status subgroup, type of pre-transplant T-cell depletion (TCD versus TCR with post-Cy), age, gender, race, and diagnosis. The fitted model, summarized in , shows that higher DSA was significantly associated with a larger Prob(GF) in C1Q+ patients, with Pr(β > 0 | Data) = .95, and was moderately significantly associated with a smaller Prob(GF) in C1Q- patients. No other covariates had a significant effect on Prob(GF).


The 2010 Affordable Care Act (ACA) included roughly 165 provisions to improve Medicare's finances.
The Medicare Trustees Report, which reflects the ACA provisions, shows dramatically lower cost projections for Medicare in the future.
The Medicare actuaries also produce alternative projections assuming that the legislated restraints on growth in payments to health providers are not feasible.
A review of both sets of projections over the past six years shows that the gap between them is narrowing due to declines in the alternative cost projections.
However, a significant gap still remains, which underscores the inherent uncertainty involved in long-range projections.


text:
Q: dynamic image in rdlc not appear correctly I have this hirarcy in my project
Report forlder -> Image Folder , Reports -> Rdlc
in rdlc I set the image source to external and use parameter
when add the parameter to report call the report not appear
I write the parameter like
"file:images\icon.jpg" is there an certain extension to use or why this cause the report to not appear ,I tried to remove the image and the report work fine

A: you should pass the complete image path to your image in this way if you pass it like you've done I don't thik it will work.
ReportViewer1.LocalReport.EnableExternalImages = true;
ReportViewer1.LocalReport.SetParameters(new ReportParameter("image", "file:///" + Server.MapPath("~/images/icon.jpg",true));


text:
Q: how to plot the comparison of the overlay bar chart with pgfplot/tikz? I have the code to plot the overlay bar chart with pgfplot/tikz. However, I would like to plot another group of data for comparison. Could you give me a hand doing that? That is, I have the overlay bar chart like "I I I", I would like to plot the comparison of the overlay bar chart like "II II II". Hope everything is clear. Thanks!
\begin{figure}
    \centering
    \begin{tikzpicture}
    \begin{axis}[
        ybar stacked,
        bar width=15pt,
        ymin=0,ymax=300,
        % nodes near coords,
        enlarge x limits=0.15,
        legend style={at={(0.5,1)}, anchor=north,legend columns=-1},
        ylabel={Percentage (\%)},
        ylabel near ticks,
        symbolic x coords={Q1, Q2, Q3},
        xtick=data,
        % x tick label style={rotate=45,anchor=east},
        ]
        \addplot+[ybar] plot coordinates {(Q1, 43) (Q2, 23) (Q3, 14)};
        \addplot+[ybar] plot coordinates {(Q1, 34) (Q2, 36) (Q3, 39)};
        \addplot+[ybar] plot coordinates {(Q1, 34) (Q2, 36) (Q3, 39)};
        \addplot+[ybar] plot coordinates {(Q1, 34) (Q2, 36) (Q3, 39)};
        \addplot+[ybar] plot coordinates {(Q1, 34) (Q2, 36) (Q3, 39)};
        \legend{1, 2, 3, 4, 5}
        \coordinate (A) at (100,143);
        \coordinate (B) at (20,203);
        \end{axis}
        \node at (A) {test};
        \node at (B) {test 2};
    \end{tikzpicture}
    \caption{The satisfaction of learning experience with the virtual reality lab.}
    \label{fig:experience}
\end{figure}


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When we look into a mirror, there is a lot going on. Light behaves in a very predictable way and when it reflects off of a flat mirror it follows the Law of Reflection. The ray of light approaching the mirror is called the Incident Ray and the ray of light that leaves the mirror is called the Reflected Ray. These two rays create an angle to the normal (think of it as the middle), and the Law of Reflection says that these two angles are always equal.
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