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Largest US Outbreak of Neurologic Disease to Date Uncovered – "We Need to Watch This Very Closely"
TOPICS:Children's Hospital ColoradoNeurosciencePediatricsPublic Health
By Children's Hospital Colorado January 12, 2020
Comprehensive clinical testing led Children's Hospital Colorado researchers to connect enterovirus A71, which causes Hand, Foot and Mouth Disease, to outbreak of neurological illness.
The Lancet Infectious Diseases recently published the results of an observational study led by researchers on Children's Hospital Colorado Infectious Disease and Neurology teams, along with counterparts at the Centers for Disease Control and Colorado Department of Public Health and Environment. The study was conducted from March 1 to November 30, 2018, and led to a discovery of the largest outbreak of enterovirus A71 (EV-A71) in the United States.
"We need to watch this very closely." — Kevin Messacar, MD
Since the 1990s, every 1 to 3 years, EV-A71 has caused large-scale, and sometimes deadly epidemics in the Asia-Pacific region, which has prompted the development of EV-A71 vaccines. In the United States, detections of this virus have been small-scale and sporadic. However, the unique symptoms, unusually high number of cases, and the geographic clustering of children who were observed during this study, indicated an outbreak.
"We need to watch this very closely," said Kevin Messacar, MD, pediatric infectious disease physician and researcher at Children's Hospital Colorado and University of Colorado Anschutz Medical Campus. "Enhanced surveillance is needed in order to determine whether this outbreak was an isolated event, or a warning of impending cyclic outbreaks of EV-A71 neurological disease in the U.S."
In addition to highlighting the need to improve enterovirus surveillance, the observational study also helped identify what other medical providers should be looking for. Children with EV-A71 disease were best differentiated from children with other enteroviruses by the neurological findings of myoclonus (quick, involuntary muscle jerks), ataxia (dizziness), weakness and autonomic instability (dysregulation of heart rate, blood pressure and perfusion). Often times these symptoms can be misunderstood or misattributed to other diagnoses — especially among young children.
Finally, it's important to note that these viruses tend to appear in seasonal waves. If through additional surveillance efforts, the United States continues to see enteroviruses circulating that cause neurological illness, the development of antivirals and vaccines may need to become a priority.
"Were it not for Children's Hospital Colorado's ongoing interest and commitment to the study of enteroviruses, this outbreak would probably not have been detected," noted Drs. Carol Glaser and Mike Wilson in a commentary published alongside the Lancet study. "The USA has yet to have large-scale epidemics of enteroviruses as are seen in Asia and other countries, but it should take steps to become better prepared."
"Clinical characteristics of enterovirus A71 neurological disease during an outbreak in children in Colorado, USA, in 2018: an observational cohort study" by Kevin Messacar, MD; Emily Spence-Davizon, MPH; Christina Osborne, MD; Craig Press, MD; Teri L Schreiner, MD; Jan Martin, MD; Ricka Messer, MD; John Maloney, MD; Alexis Burakoff, MD; Meghan Barnes, MSPH; Shannon Rogers, MS; Adriana S Lopez, MPH; Janell Routh, MD; Susan I Gerber, MD; M Steven Oberste, PhD; W Allan Nix, BS; Prof Mark J Abzug, MD; Prof Kenneth L Tyler, MD; Rachel Herlihy, MD and Samuel R Dominguez, MD, 16 December 2019, The Lancet Infectious Diseases.
"Enteroviruses: the elephants in the room" by Carol Glaser and Michael R Wilson, 16 December 2019, The Lancet Infectious Diseases.
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Find a Kid Loco - Kill Your Darlings first pressing or reissue. Complete your Kid Loco collection. Shop Vinyl and CDs. Find album reviews, stream songs, credits and award information for Kill Your Darlings - Kid Loco on AllMusic - - Four years after his debut, an LP of clever. Kid Loco- Kill your Darlings full album. Nikolas Bickerstaff; 10 videos; 14, views; Last updated on Sep 13, Play all. Share. Loading Save.
12 Oct - 5 min - Uploaded by shinesinpines from Kill Your Darlings. Track 4. Kid Loco- Three Feet High Reefer. shinesinpines. This my first cd from Kid Loco and I like it. "Kill Your Darlings" is a good cd. All of the songs are decent. But "Horsetown in Vain" is my favorite one so far. It's the. Kill Your Darlings. Kid Loco. Released K. Kill Your Darlings Tracklist. 1. Cocaine Diana Lyrics. 2. Lucy's Talking Lyrics. 4. Three Feet High Reefer Lyrics.
Kid Loco Kill Your Darlings. By Rob Bolton. Published Nov 01, Another fine musical journey from Jean-Yves Prieur, the French producer/DJ/remixer. An easy-listening trip-hopster similar in style and intent to his countrymen Air and Dimitri from Paris, Kid Loco has an even stronger kinship with the long tradition.


Representing almost three decades of work, Trilogy explores the poetic imagery of Mexican photographer Flor Garduño. Garduño's images investigate nature, dreams, and the female form. The exhibition is divided into three sections: Bestiarium, Fantastic Women, and Silent Natures. Through a surrealist, dream-like perspective, her works recall ancient rituals and the power of the feminine. Her mystical works captivate and amaze, always evoking a deep emotional response.
William Shakespeare said that art is a mirror held up to nature. This is certainly true for Garduño's unique vision. The mirror she holds up to the world reflects many things, including--the real and the mythical, the natural and the staged, and the factual and fictional--all meant to create her own visual mystical realism.
Flor Garduño studied Visual Arts at the San Carlos Academy for the Arts at the Universidad Nacional Autónoma de México. In 1979 she began working as an assistant to Manuel Alvarez Bravo. By 1985 she published Magic of the Eternal Game the first of her many books. Her work has been awarded several important prizes including twice receiving the Swiss Federal Fund for Culture Prize, the German edition of the Kodak Award for her book Witness of Time, and the Photo District News Award for the book Inner Light.
Her photographs have been widely exhibited in Europe, Latin America and the United States and are held in many permanent collections, including The Museum of Photographic Arts, the Museum of Modern Art, the Art Institute of Chicago and the Biblioteque National in Paris. This exhibition is available for presentation through 2019.
Flor Garduño Trilogy - 240 pages with 96 plates.
Available in English and Spanish. Preface by Francisco Reyes Palma and critical text from Alfredo Lopez Austin, Tereza Siza, and Guido Magnaguagno. Published by Contrasto, Rome, IT.
Flor Garduño, the celebrated Mexican photographer, had a confession: Photography was not her first love.
Then there was Manuel Álvarez Bravo.
Four decades later, Ms.Garduño, 58, is herself a major influence on Mexican and Latin American photographers working today. Her black-and-white images — she favors still lifes, nudes, portraits, street scenes and explorations of indigenous cultures — are included in the permanent collections of the Museum of Modern Art in New York, the Art Institute of Chicago, the National Library of Paris and the Louis Museum of Cologne, among others.
A major retrospective of her work, spanning four decades, just opened at the Museum of Photographic Arts in San Diego and runs through May 29. The show, "Trilogy," offered in Spanish and English, explores Ms. Garduño's principal themes within three groups: "Bestiarium," "Fantastic Women" and "Silent Natures." The show includes 96 images made in Mexico, Poland and Switzerland (where Ms. Garduño spends part of the year).
"Bestiarium" includes some of Ms. Garduño's early work in indigenous rural communities across Mexico. In the 1980s, Ms. Garduño took a government job photographing in Mexico's countryside for use in textbooks. Working under Mariana Yampolsky, another Mexican photographer who influenced her, Ms. Garduño discovered her own style. One of the most striking images of this collection, shot in Mexico in 1987, depicts a man holding a bull by a rope while a goat stands on the bull (Slide 1). What does it mean? Does it mean nothing or everything about life?
"Fantastic Women" features images that explore being a woman in this universe. One of the most striking, "Rapto," depicts a woman in a gauzy toga, seen from behind, holding a raptor with outstretched wings in her outstretched hand. Silent nature includes surreal still lifes, many of them hard to encapsulate with words.
Case in point: Ms. Garduño is currently working on a book of portraits, not necessarily in Mexico.
Women have long been portrayed in art as inscrutable ciphers, from the ancient Greek Kore statues with their tight smiles to the Mona Lisa. But photographer Flor Garduño plays with those enigmatic representations, showing women as not only idealized and mysterious creatures but also powerful and self-fulfilled beings.
"Mujeres Fantasticas" (Fantastic Women) is one of three themes richly explored in the Garduño exhibition "Trilogy" at the Museum of Photographic Arts in San Diego through May 29. The show's 96 works include pieces shot in Poland, the artist's native Mexico and in Switzerland, where she spends part of the year.
Reached by phone in Mexico City, Garduño said in Spanish that the "Trilogy" groupings — women, beasts and what she calls "silent natures" — reflect her interests throughout her career. Born in 1957 in Mexico City, Garduño studied visual art and then began working as a photographer in the early 1980s, when she landed a job taking pictures for the Ministry of Education. She gained recognition in Mexico first, then in the U.S. and in Europe, for photos of indigenous people, portraits and nudes, and for her street photography and still lifes.
Many photos evoke myth and magic through unexpected pairings.
"Rapto, Suiza," from 2008, suggests female and animal strength, either as complements or perhaps as competitors. It shows a woman from behind, her body covered in a gauzy veil that billows in the wind. The bird's broad wings seem to be lifting off from her hand. It's impossible to tell where animal ends and woman begins. She could be about to take flight, or she could be anchoring the bird. Is the woman human or divine?
The part of the exhibition themed "Bestiarium" explores animals and includes an image taken in Mexico in 1987. A man holds a bull by a rope, and a goat stands on the bull. The goat was known for standing on cows and bulls, and the photographer just captured the moment.


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NHD REGISTRATION LINK – BY FEBRUARY 11!
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In class February 8-9 – The Progressives!
Let's check out how the Progressives tried to solve the problems of society at the turn of the century by completing a Progressive Movement in a Nutshell. Make some connections too!
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Assignment February 4/5 – Get Progressive!
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«Дмитрий Пожарский» — советский крейсер проекта 68-бис.

История строительства
Заводской номер: 445.
 31 августа 1951 года — зачислен в списки ВМФ.
 28 февраля 1952 года — заложен на ССЗ № 189 («Завод им. С. Орджоникидзе», Ленинград).
 25 июня 1953 года — спущен на воду.
 31 декабря 1954 года — введен в строй.

История службы
 31 января 1955 года — вошел в состав 4-го ВМФ.
 24 февраля 1955 года — переведен на КСФ.
 7 сентября 1955 года — после перехода по Севморпути из Североморска на Дальний Восток переведен в КТОФ.
 21-26 июня 1956 года — визит в Шанхай.
 В 1964 году имея на борту курсантов ТОВВМУ, выполнил поход по маршруту: Японское море, Восточно-Китайское море, Южно-Китайское море, Филиппинское море и через Сангарский пролив возвратился во Владивосток.
 28-31 марта 1968 года — визит в Мадрас.
 3-6 апреля 1968 года — визит в Бомбей.
 17-24 апреля 1968 года — визит в Могадишо.
 11-19 мая 1968 года — визит в Умм-Каср, Ирак.
 25 мая — 2 июня 1968 года — визит в Карачи.
 5-9 июня 1968 года — визит в Бендер-Аббас.
 25-28 июня 1968 года — визит в Аден.
 6-11 июля 1968 года — визит в Коломбо.
 25 апреля 1969 года — 23 октября 1970 года — проходил капремонт на «Дальзаводе» во Владивостоке.
В 1971 году — поход с курсантами по маршруту 1964 года.
 10 ноября 1974 года — 10 июня 1975 года — несение боевой службы, Индийский океан. Слежение за авианосцем «Констелейшен». Заходы Мадрас, Могадишо, Аден, Порт-Луи.
 Прибыв в Порт-Луи (Маврикий), экипаж корабля с 15 февраля по 1 марта 1975 г. вместе с ПМ-125 две недели оказывал помощь его населению, пострадавшему от последствий тропического урагана «Жервез».
 июнь-июль 1977 года морская практика курсантов 1-го курса ТОВВВМУ им. С. О. Макарова. Обошли вокруг Японии, через Корейский пролив, далее с заходом в Советскую Гавань (стоянка 3 дня) и обратно во Владивосток через четвёртый Курильский пролив и через пролив Лаперуза.
 30 января 1979 года  — поставлен в средний ремонт на «Дальзаводе» во Владивостоке.
 5 марта 1987 года — разоружен и исключен из состава ВМФ.
 16 сентября 1987 года — расформирован.
 1990 год — продан частной индийской фирме на металл.

Командиры
Григорьев Виктор Гаврилович
Колышкин И.М. (1955-1956)
Казенный Б.В. (1956-1957)
Щербаков А.А. (1957-1961)
Косяченко Марк Алексеевич (1961-1963)
Дорогин Л.Н. (1963-1965)
Ясаков Н.Я. (1965-1968)
Сидоров А.М. (1968-1969)
Довбня Петр Иванович (1969-1972)
Громов Феликс Николаевич (октябрь 1972 — октябрь 1975)
Сергеев Валерий Николаевич (октябрь 1975 — март 1979)
Мишанов Валентин Григорьевич

Примечания

Литература

Крейсера проекта 68-бис
Суда по алфавиту

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Dubai Welcomes 13.2m International Visitors in 2014
Dubai, UAE; 3 May 2015: Dubai welcomed a total of 13.2 million international overnight visitors in 2014, according to new statistics issued by Dubai's Department of Tourism and Commerce Marketing (Dubai Tourism). Representing a year-on-year increase of 8.2 per cent – significantly higher than the global average of 4.7 per cent – the growth reflects the continuing strides that the Emirate is making towards realising Dubai's Tourism Vision for 2020, which aims to welcome 20 million visitors by the start of the next decade.
The 13.2 million figure is the headline statistic of the inaugural 'Dubai Annual Visitor Report', issued at this week's Arabian Travel Market (ATM). Differing from previously announced statistics on guests staying at Dubai's hotel establishments, the figure is a measure of all international visitors travelling to Dubai and staying for at least one night, in hotel accommodation and holiday rentals, with friends and relatives, and on board cruise ships.
The Dubai Annual Visitor Report is a collation of key tourism metrics, trends and insights drawn from Dubai Tourism's comprehensive research, which involves monitoring performance across global demand and competitive intensity, the effectiveness and supply of Dubai's proposition, and the emirate's ability to deliver a rounded destination experience to leisure and business travellers.
Commenting on the results, His Excellency Helal Saeed Almarri, Director-General of DTCM, said: "The Dubai Annual Visitor Report provides insights into how and why Dubai achieved significant visitor growth in 2014, continuing the upward trend of recent years. With the year-on-year increase of 8.2 per cent being significantly higher than the global average, the report demonstrates Dubai's broadening appeal as a tourism destination among multiple geographies and audience segments, highlighting both the success achieved to date and the opportunity for continual growth.
"The 2014 success is especially promising considering pressures on a number of source market economies and the 80-day partial closure of Dubai International Airport (DXB). The results are a tribute to the vision of His Highness Sheikh Mohammed bin Rashid Al Maktoum, UAE Vice President, Prime Minister and Ruler of Dubai, and the continued resolute partnership between the government and the private sector.
Having traditionally released annual data on hotel establishment guests, the new report encompasses all international overnight visitors, painting a broader picture of the successes, challenges and opportunities of the Emirate's tourism economy. The research behind the report enables us to further enhance our targeted marketing activity, which in the past year has included the development of extensive digital, social media and PR partnerships with some of the most influential channels in the industry."
Significantly, while sustained momentum in Dubai's traditional source markets saw the majority of the Emirate's top ten source markets growing around eight per cent, there was also double-digit growth from a number of emerging travel source countries home to fast-growing middle-class populations with high disposable incomes. Examples include China, Nigeria and Brazil, in addition to several Eastern European nations – a result of the easing of UAE visa policies applying to 13 EU member states in March 2014.
His Excellency Helal Saeed Almarri, Director-General of DTCM, said: "Dubai has strategically sought to ensure a fragmented source market approach, mitigating risks associated with over reliance on any specific region or geography. Fifty-five per cent of last year's visitors came from our top ten source markets, the majority of which saw sustained growth, and there was healthy acceleration in many emerging feeder geographies. We will continue to work with our partners to further diversify our markets and leverage opportunities for growth, with one example being maximising the potential of Eastern European markets, from which we have already seen a positive result from the easing of visa regulations in March last year and the subsequent flight launches to the region by Emirates and flydubai towards the end of 2014."
Reasons for growth
Despite an 80-day partial runway closure from May to July, 2014 saw Dubai International Airport emerge as the world's busiest for international passengers, surpassing London Heathrow for the first time. The airport welcomed 70.5 million passengers in 2014, an increase of 6.1 per cent, while overall seat capacity to Dubai increased 7.2 per cent year-on-year to 48.6 million. Dubai's two home-grown airlines, Emirates and flydubai, achieved exceptional growth in fleet size and global footprint expansion; the former launching new routes to eight destinations and adding circa 420,000 seats, the latter to 18 destinations and approximately 180,000 seats. The growth in aviation capacity supports the World Economic Forum's assertion that "Dubai's greatest competitive advantage in tourism is its ability to provide a world-class international hub for global air travellers." Dubai's cruise industry, meanwhile, also contributed to growth thanks to the opening of Dubai's third cruise terminal, and 425,000 passengers are expected to arrive on cruises into Dubai in 2015, a 30 per cent increase over the previous year.
2014 also saw improved accessibility to Dubai, driven by the easing of UAE visa policies that have it made it easier and cheaper to visit the emirate. Citizens from a total of 46 countries can now obtain a visa on arrival, boosted by the March 2014 addition of 13 EU member states to the existing 15 member states already eligible. Positive results can already be seen in the increase in visitors from Bulgaria, Hungary and Romania, for example, up by 104 per cent, 86 per cent and 64 per cent respectively.
At the same time, the breadth and depth of Dubai's destination proposition has continued to evolve and diversify, attracting more visitors and contributing to increasing visitors' length of stay. A total of 46 new hotel and hotel apartment establishments opened in 2014, including the likes of Marriott Hotel Al Jaddaf, Warwick Hotel Sheikh Zayed, Sheraton Grand Hotel and Four Seasons Resort Dubai, as well as a host of new attractions such as The Beach at JBR, Jumeirah Corniche and At The Top, Burj Khalifa SKY. These additions, together with Dubai's world-class approach to customer service across all tourism sectors and continued infrastructure developments, have contributed to the ongoing enhancement of Dubai's destination offering and its global appeal.
His Excellency Helal Saeed Almarri commented: "Dubai's sustained growth is a result of the pursuit of excellence across all parts of the tourism economy by the private and public sectors, constantly seeking to be the number one destination for both leisure and business travel. This applies to both creating a compelling proposition and delivering a superior end-to-end experience, and has resulted in the creation of a destination offering that appeals to both leisure and business visitors, and to families, couples and solo travellers. Continuous enhancements to the offering have contributed to an average length of stay of 7.8 days, surpassing that of London and similar to that of New York, and there are numerous additions to the offering, across attractions, experiences, hotels and restaurants, due to open in 2015 and 2016."
Multiple audiences
A key statement within the Dubai Tourism Vision for 2020 is the ambition to become the world's number one family destination, with the objective of capturing a substantial share of one of the highest potential segments in the global tourism market. According to Thomson Reuters, family travel accounts for over 12.5 per cent of the USD 1.7 trillion global tourism market, and is projected to grow at circa 5 per cent up to 2020. With Dubai's top source markets for families being the Kingdom of Saudi Arabia, Oman and India, the Emirate continues to expand its offering for the segment, with the next two years seeing the opening of attractions including Dubai Safari Park, Dubai Opera House, Legoland Dubai, Hollywood-themed Motion Gate and Bollywood Parks Dubai.
Business travellers are another stated target segment for the Emirate, and in 2014 the number of visitors travelling for meetings, exhibitions, conferences and events (MICE) grew by 10 per cent.
His Excellency Helal Saeed Almarri concluded: "In delivering the ambitious targets of our Tourism Vision for 2020, there are no doubt challenges ahead, but the continued collaboration of all stakeholders within the tourism industry and related sectors ensure we are well positioned for success."
Posted by Bec on May 5th, 2015 | Dubai Welcomes 13.2m International Visitors in 2014 | No Comments
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Rosy Wertheim 'String Quartet': Dutch Flair
Published by Alex Burns on 25th November 2020 25th November 2020
Rosy Wertheim: String Quartet
The Dutch composer, Rosy Wertheim (1888-1949), was one of the first female composers who completed her professional music education and garnered some international acclaim for her music. Although spending the start and end of her life in her homeland of the Netherlands, Wertheim travelled all over the world to meet new artists and to champion social causes that were close to her heart. Wertheim lived in Paris, Vienna and New York for a number of years at a time, with Paris becoming a significant place of interest for her. When World War II broke out, Wertheim, a practising Jew, went into hiding in the Netherlands. Although faced with difficult situations throughout her life, Wertheim left behind over 80 works in her archive.
Composed in 1932, Wertheim's only String Quartet showcases her management of textures, melodies and the balancing of sounds to create a palpable chamber work. Although clocking in at just over 10 minutes in duration, Wertheim's String Quartet manages to fit a lot into the three movements.
Movement I – Allegro Con Moto
The opening viola rush signals the violins to begin their ascending passage. Once the cello enters, the full experience of Wertheim's textures comes to fruition. The quick pace and cheeky melodies bounce around the ensemble, with all parts having their given turn. A short unison passage unites the ensemble, before the tempo picks up again the instruments go their separate ways. The themes are invigorating and exciting, with the slower passages adding a new dimension to the movement. After a quick reprise of the opening material, the first movement comes to its thrilling close.
Movement II – Intermezzo
The token slow middle movement starts with the upper strings as they introduce the lamenting main theme. Firmly set in the minor here, the music is emotional and shows Wertheim's values in building effective melodies and textures. As the ensemble rises and falls together, the music begins to fluctuate, creating rippling waves of emotions across the music. As expected, this movement ends delicately and quietly as the music fades into nothing.
Movement III – Allegro Energico
The finale, full of energy and vigour, starts with the theme in the violins. As the other strings accompany, the melody is soon passed around the ensemble. Fast scalic passages begin a call and response section between the top and bottom halves of the ensemble. A slow and reflective central section highlights themes from the middle movement, and offers a sigh of relief within the music. As the tempo begins to rush off once more the final few bars of the movement tie together all of Wertheim's best bits of the quartet, which culminate in two big unison chords before the final flourish finishes this thrilling quartet.
You might also enjoy… Nancy Dalberg: String Quartet No.1
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← Nico Rosberg: "We want to put on an amazing show…"
Christian Horner: "We were pretty competitive at the end of the race…" →
Toto Wolff: "They did it in a fantastic and spectacular way…"
Mercedes boss Toto Wolff says that Lewis Hamilton and Nico Rosberg will be allowed to race each other throughout the season.
He also acknowledged that it was important to have two drivers who could be trusted by the team.
"You need to have the drivers who understand where the team came from, and that it's important not to risk the image of such a brand," he said. "We're representing a big brand, so you need to know what you do. And they did it in a fantastic and spectacular way. I'm happy."
He confirmed that the situation would remain unchanged.
"Yes, until we lose some front wings! Then we sit down again and discuss if this was [the right] strategy. They're racing drivers, it's academic… Let's leave it there!"
Asked if he has any doubts about allowing them to race, in Bahrain he said: "Turn 3 after the start of the race I had doubts! I was like, 'No please, not for one and a half hours now!'. And then at the end when we had the restart we discussed that we trusted the drivers. We knew that they wouldn't risk their own car and the one of the other driver. Nico is still in the championship lead, it's about collecting solid points."
"You know what we said was exactly the same sentence to both of them, just reminding them in a moment before the heat would start just to say don't forget what we discussed. This was not at all a strategic call, it was just a gentle reminder of where we came from."
Regarding the decision to put Rosberg on primes in the middle stint, he said: "We knew that the second car only had a chance to win if you offset him with the strategy. Both cars were on a strategy to win the race."
Wolff said that the team thought Rosberg would be able to pass Hamilton in the closing stint.
"That was the theory, but Lewis had an amazing first couple of laps on the prime. We saw it in a previous stint, one of the Force Indias proved to be really quick on the prime."
Meanwhile Wolff said he was not frustrated by the negative comments from Bernie Ecclestone and Luca di Montezemolo.
"We had some good discussions with all of them today, and I think it's pretty clear that we love F1 and we don't want to talk F1 down, and this is the kind of spirit that we want to have in our future discussions. It's not frustrating. It's good that they came here, and I think that race came at the right time."
Filed under F1 News, Grand Prix News
One response to "Toto Wolff: "They did it in a fantastic and spectacular way…""
Adam, how big do you think Merc's real advantage is? It seems to be around 2.5 – 3 seconds per lap. Horrible if one car is at the front: he can just cruise to the flag, but if they let their drivers carry on racing like that, then it's going to be great.
Assuming they do let them carry on racing that hard, then it's not going to be long before they have contact.


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Home >> Hong Kong
Cantonese culture in Hong Kong heading for extinction
HONG KONG (UCAN): "Politicisation is inevitable, because the teaching materials and textbooks come from China," a political commentator in Hong Kong, Lam Kei wrote.
"They are taking the opportunity to turn Putonghua teaching into brainwashing sessions," Lam said.
Lam's comments come amid growing concerns that the increasing use of Putonghua (Mandarin) in Hong Kong is posing a threat to the city's indigenous culture.
The the government's Census and Statistics Department, in a 2016 census, found that around 166,000 new Hong Kongers—those who migrated from across the border with China—have taken up residence in the city over the past seven years.
Fewer of them said they could speak Cantonese, one of the city's official Chinese languages.
Cantonese was the "usual spoken language" for more than 91 per cent of the population in 2016, but was spoken by just under 70 per cent of migrants from China, the department said.
One resident, Chen Yang, told Radio Free Asia, "I have lived in Hong Kong for more than 20 years and my feeling is that the status of Cantonese is changing in favour of Putonghua."
Chen noted, "When I had just moved to Hong Kong, Putonghua was looked down on as the language of a hick from the sticks, a closed society."
The trend has raised fears among local commentators who say the city's traditional freedoms and way of life are under threat amid growing political influence from Beijing.
Lam observed that the shift away from Cantonese in Hong Kong's education system has been gradually accelerating ever since the 1997 handover to Chinese sovereignty.
"Hong Kong is discovering, just like Guangzhou and Shenzhen a few years ago, that it is the last bastion of Cantonese, and that (the language) is heading towards extinction," Lam wrote.
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Cantonese vs Putonghua
threat to the city's indigenous culture


Twelve luxury rooms with a spectacular rustic and modern design, nine of them endowed with kingsize bed and three with two beds. There are four rooms per bungalow, two in the ground floor, two in the second floor. Each bungalow is surrounded by huge garden areas with terrace and balcony offering a wonderful panoramic view. Each Design room has a spacious bathroom (with shower), walk-in closet, safe, hair dryer, fireplace and amenities.


text:
George Leo Haydock
Haydock, GEORGE LEO, priest and Biblical scholar; b. April 11, 1774, at Cottam, near Wood Plumpton, Lancashire; d. November 29, 1849, at Penrith, Cumberland. At an early age he was placed in a school kept by the Rev. Robert Banister at Mowbreck Hall, near Kirkham, and in 1785 entered the English College of Douai. In the beginning of the French Revolution he escaped from Douai, August, 1793, in company with his brother Thomas and one of the minor professors. He stayed for a short while at Old Hall Green, near Ware, Hertfordshire, but went to his home at the Tagg on November 3, 1794, where he remained until January, 1796, when he rejoined some of his Douai companions in the college at Crook Hall, Durham. After being ordained priest on September 22, 1798, he held the offices of general prefect and master of all the schools under poetry till January 26, 1803, receiving £5 (25 dollars) for his five years' work. Next he took charge of the poor mission at Ugthorpe, Yorkshire, and in July, 1816, the mission of Whitby, whence he was removed on September 22, 1830, to the mission at Westby Hall, Lancashire, owing to a misunderstanding with his superiors. On August 19, 1831, he was forbidden to say Mass by Bishop Penswick, whereupon he retired for the succeeding eight years to the Tagg, devoting himself to study. In 1832 he twice appealed to the Propaganda, but both his letters were intercepted and sent to the bishop; after his third appeal in 1838, his faculties were restored on November 18, 1839, and he was appointed to the mission at Penrith where he spent his last ten years. Father Haydock's chief publication was a new edition of the English translation of the Latin Vulgate first published at Reims in 1582, and at Douai in 1609; Bishop Challoner's text of 1750 was the basis of the work, but in the New Testament Dr. Troy's edition of 1794 is largely followed. The notes are partly original, partly selected from other writers, those on the New Testament not having been compiled by Father Haydock. The edition appeared in Manchester, 1812-4; Dublin, 1812-3; Edinburgh and Dublin, 1845-8; New York, 1852-6; The other works published by Father Hay-clock are: "The Tree of Life; or the One Church of God from Adam until the 19th or 58th century" (Manchester, 1809); "Prayers before and after Mass proper for Country Congregations" (York, 1822); "A Key to the Roman Catholic Office" (Whitby, 1823); "A Collection of Catholic Hymns" (York,1823); "Method of Sanctifying the Sabbath Days" (York, 1824). Besides his published books, Father Haydock left a number of works in manuscript, five volumes of "Douay Dictates"; four volumes of "Psalms and Canticles in the Roman Office"; several volumes of "Biblical Disquisitions"; a treatise on "The Various Points of Difference between the Roman and the Anglo-Catholic Churches"; etc. The pecuniary risks of the press deterred him from publishing these works.
A. J. MAAS


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Lina Palaiodimou, MD
Brown DL, Shafie-Khorassani F, Kim S, Chervin RD, Case E, Morgenstern LB, et al. Sleep-Disordered Breathing Is Associated With Recurrent Ischemic Stroke. Stroke. 2019;50:571–576.
The role of sleep-disordered breathing (SDB) is well established in the development of a first stroke or death from any cause. Previous studies have shown that SDB is associated with an increased incidence of stroke or death from any cause, and this association is independent of other cardiovascular and cerebrovascular risk factors. This condition appears both in prestroke patients and in poststroke patients, and is more often obstructive than central. An association between SDB and recurrent strokes is also being presumed, but there are no sufficient prospective data to demonstrate and support this association.
The study of Brown et al. is an attempt to enrich the scarce data regarding the interaction between SDB and recurrent strokes. More specifically, the primary endpoint of this study is to investigate the association between SDB and recurrent ischemic stroke and secondary endpoints are: possible association between SDB and all-cause poststroke mortality and possible influence of ethnicity on the interaction between SDB and outcome measures (recurrent stroke or mortality). For that purpose, the investigators designed a prospective study of 842 patients who suffered from an index ischemic stroke and underwent a sleep apnea study shortly after the event. Additionally, patients had to be above 45 years old and be a resident of Nueces County, as the study was limited in 7 acute care hospitals of this certain county. Demographics, stroke risk factors, clinical variables and the REI (which is the sum of apneas plus hypopneas per hour of sleep apnea study duration) were recorded. Patients were followed until the first recurrent stroke, death or the last follow-up date, whichever came first. Proportional hazard models were conducted, both unadjusted and adjusted, to assess the association between REI and recurrent stroke or death. Finally, the interaction of ethnicity, REI and each outcome was statistically analyzed.
By strokeblog|March 29th, 2019|clinical, epidemiology and genetics|0 Comments
Richard Jackson, MD
Wabnitz AM, Derdeyn CP, Fiorella DJ, Lynn MJ, Cotsonis GA, Liebeskind DS, et al. Hemodynamic Markers in the Anterior Circulation as Predictors of Recurrent Stroke in Patients With Intracranial Stenosis. Stroke. 2018;50:143–147.
Ashley M. Wabnitz MD et al. introduced the finding that despite the superiority of aggressive medical management (AMM) in intracranial atherosclerotic arterial stenosis (ICAS), 15% of patients still had primary end point of stroke during a median follow up of 32.4 years.
The study was a post-hoc analysis of 154 patients of the total 227 patients with intracranial stenosis randomized to AMM, 49 ICA and 105 MCA. Non-MCA territory infracts and stenosis were excluded, as well as 53 patients for baseline imaging not corresponding to the qualifying event. All patients included in SAMMPRIS had angiographically verified 70-99% stenosis of ICA, MCA, vertebral or basilar arteries. Infarct patterns were classified into core, perforator, internal borderzone, or cortical borderzone based on published templates from a retrospective analysis of WASID lesions. Interobserve agreement for infarct patterns was k=0.8. Evaluation of collaterals was assessed by a validated scale by the American Society of Interventional and Therapeutic Neuroradiology/Society of Interventional Radiology; however, collaterals were assessed as impaired versus not impaired despite the validated scale having 4 grades.
By strokeblog|March 27th, 2019|clinical, prevention|0 Comments
Elena Zapata-Arriaza, MD
@ElenaZaps
Campbell BCV, Majoie CBLM, Albers GW, Menon BK, Yassi N, Sharma G, et al. Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis of individual patient-level data. Lancet Neurol. 2019;18:46-55.
Image selection in acute stroke involves a radiological prognostic marker in patients with large vessel occlusion. Ischemic penumbra is defined as hypoperfused tissue, which is at risk for irreversible damage (i.e., infarction) if blood flow is not rapidly restored and can widen the treatment time window for selected patients as seen in recent positive endovascular trials. The possibility of increasing target population that would experience clinical benefit after performing mechanical thrombectomy motivates the assessment of influence of ischaemic core volume and mismatch volume on functional outcome after endovascular treatment.
The HERMES collaboration performed a systematic review and meta-analysis from all randomized controlled trials published in PubMed from January 2010 to May 2017, assessing endovascular thrombectomy predominantly performed with stent retrievers versus medical therapy in patients with anterior circulation ischaemic stroke, according to PRISMA guidelines. For CTP, irreversibly injured ischaemic core was defined as a relative cerebral blood flow of less than 30% of normal brain blood flow. For diffusion MRI, ischaemic core was defined as an apparent diffusion coefficient of less than 620 μm²/s. The association of ischaemic core and penumbral volumes with 90-day mRS score (functional independence, defined as mRS score 0–2) and functional improvement by at least one mRS category in all patients and in a subset of those with more than 50% endovascular reperfusion was evaluated as highlights among other issues. Symptomatic intracerebral haemorrhage was assessed as a safety outcome.
By strokeblog|March 26th, 2019|clinical|0 Comments
Dr. Raul Nogueira
A conversation with Raul Nogueira, MD, Professor of Neurology, Neurosurgery and Radiology,Emory University School of Medicine, Director of Neuroendovascular Service, Marcus Stroke & Neuroscience Center, Grady Memorial Hospital, on endovascular thrombectomy for acute ischemic stroke with mild symptoms.
Interviewed by Mark R. Etherton, MD, PhD, Assistant in Neurology, Massachusetts General Hospital, Instructor, Harvard Medical School.
They will be discussing the paper "Mechanical Thrombectomy in Patients With Milder Strokes and Large Vessel Occlusions: A Multicenter Matched Analysis," published in the October 2018 issue of Stroke.
Dr. Etherton: This is a very interesting paper that I think raises some good questions about the triage and management approaches to patients with large vessel occlusions and low severity ischemic strokes as assessed with the NIHSS. Could you speak a little bit regarding your management approaches to this patient population, including if any differences whether the stroke was involving the anterior or posterior circulation?
Dr. Nogueira: The first thing you have to acknowledge is there is not a lot of data to answer this question. The data is mostly retrospective in nature. There are methodological issues with these retrospective approaches in that you have to analyze them as intention-to-treat. So you have to separate out the cohorts as immediate treatment versus no immediate treatment. In reality, you really have three groups: immediate mechanical thrombectomy (MT), immediate medical therapy, and immediate medical therapy with subsequent deterioration and rescue MT. You cannot group this last group with the MT group because your initial intent was to treat this group medically. This is the equivalent of cross-over in a clinical trial which creates methodological problems.
By strokeblog|March 25th, 2019|author interview, clinical|0 Comments
Kristina Shkirkova, BSc
Chen G, Wang A, Li S, Zhao X, Wang Y, Li H, et al. Long-Term Exposure to Air Pollution and Survival After Ischemic Stroke. Stroke. 2019;50:563-570
The risk factors of stroke, a major contributor to the global burden of disability and mortality, include environmental exposure to air pollution. Pre-stroke long-term exposure to air pollution derived particulate matter is associated with higher mortality rates after ischemic stroke, the authors of the new study from China report.
The study by Chen et al. estimated the daily exposure of a cohort of 12291 ischemic stroke patients to air pollutants via a machine learning algorithm that accounted for temporal and spatial meteorological and satellite monitoring data for the geocoded location of patients' home address. The authors looked at 3-year pre-stroke air levels of particulate matter with aerodynamic diameter ≤10 μm and nitrogen dioxide and the rates of mortality after ischemic stroke within 1 year follow up period between 2007 and 2008. Smaller coarse particles in the air mixture were the primary interest in this study, as they contain the most toxin and are able penetrate deeper through the respiratory system and cause an inflammatory response.
By strokeblog|March 22nd, 2019|clinical, epidemiology and genetics|0 Comments
Wu S, Yuan R, Wang Y, Wei C, Zhang S, Yang X, et al. Early Prediction of Malignant Brain Edema After Ischemic Stroke: A Systematic Review and Meta-Analysis. Stroke. 2018;49:2918-2927
In cases of unsuccessful recanalization or prolonged hypoperfusion, large infarctions may occur, leading to malignant brain edema. In addition to decompressive craniectomy, there are few therapeutic strategies to alleviate this serious complication of ischemic stroke. Given its high mortality and disability in survivors, high-risk patients identification could lead to a more intensive monitoring and maybe an early intervention.
The authors performed a systematic review and meta-analysis based on Medline and Embase search from inception to March 2018, with studies assessing predictors or predictive models for malignant brain edema after ischemic stroke. Malignant edema was defined as a syndrome of clinical worsening (or death or requirement for decompressive hemicraniectomy) with imaging evidence of brain swelling. Studies included were observational with at least 1 potential predictor measured or a developed predictive model for malignant edema, and with published full-text report in a peer-reviewed journal. Studies were excluded if outcomes were defined as imaging-based edema or as clinical worsening or death not attributable to brain edema, or if the study assessed cross-sectional associations. Moreover, the authors performed a post-hoc literature search in May 2018 to identify randomized controlled trials (RCTs) to provide more robust evidence for the effect of reperfusion therapies and successful revascularization on the development of malignant edema. Reperfusion therapies included either intravenous thrombolysis or endovascular interventions.
Alejandro Fuerte, MD
@DrFuerte1
Desai SM, Rocha M, Jovin TG, Jadhav AP. High Variability in Neuronal Loss: Time Is Brain, Requantified. Stroke. 2018;50:34–37
Acute ischemic stroke caused because of large-vessel occlusion (LVO) is a neurological emergency characterized by abrupt interruption in blood flow that causes rapid neuronal death. It has been shown that time in this situation is directly proportional to the infarcted brain tissue. In this context, there is an approximate loss of 1.9 million neurons every minute, which means "run!". However, as we have observed in the DAWN and DEFUSE 3 trials, there is inter-individual variability, and the therapeutic window can be widened in those cases of patients whose ischemic core grows slowly.
The main goal of Desai et al. was to calculate the rate of loss of brain tissue within a cross-section of LVO patients with different infarct growth rate (IGR). For this purpose, they performed a retrospective review of a prospectively acquired database of acute ischemic strokes with occlusion of the internal carotid artery or middle cerebral artery. Ischemic core volume was measured with automated software and time from last known well to imaging was recorded. For the final calculations, they used what is already known about the volume of forebrain (total number of neurons, synapses, and myelinated fiber length) and, with the results, a statistical analysis was performed.
Gurmeen Kaur, MBBS
@kaurgurmeen
Shah S, Xian Y, Sheng S, Zachrison KS, Saver JL, Sheth KN, et al. Use, Temporal Trends, and Outcomes of Endovascular Therapy after Interhospital Transfer in the United States. Circulation. 2019
The current decade has seen a revolution in stroke care with the advent of endovascular therapy (EVT) and extended timelines for stroke intervention. With the expansion of stroke care, there is a tremendous increase in the need for angiographic suites and providers. Most smaller, non thrombectomy capable centers have set up contracts with academic or bigger centers nearby to transfer their stroke patients for emergent large vessel occlusions.
However, given that the number of treatable strokes far exceeds the number of thrombectomy capable centers, it is the right time to review our nationwide policies on transfers for improved patient care and quality improvement. In this paper, authors Shah et al. have done a great job elucidating the temporal trends in transfer of patients for EVT and how those transfer trends are influencing the final outcome, using the Get with the Guidelines database.
By gkaur|March 18th, 2019|clinical|0 Comments
Robert W. Regenhardt, MD, PhD
@rwregen
Jadhav AP, Zaidat OO, Liebeskind DS, Yavagal DR, Haussen DC, Hellinger FR, et al. Emergent Management of Tandem Lesions in Acute Ischemic Stroke: Analysis of the STRATIS Registry. Stroke. 2018;50:428–433.
With the 2015 trials irrefutably showing the superiority of endovascular thrombectomy (ET) over intravenous tPA alone for the treatment of stroke secondary to large vessel occlusion (LVO), and the 2018 trials showing it may be effective for up to 24 hours from symptom onset, current research efforts focus on expanding the number of patients who may be eligible for this highly effective treatment (e.g., larger core, more distal occlusions) and optimizing protocols for more complex cases. The latter is exemplified by questions that remain about the best approach to treating tandem lesions, which involve both the cervical internal carotid artery (ICA) and an intracranial artery. The most common etiology is cervical ICA atherosclerosis, but tandem lesions can also result from cervical ICA dissection.
Perhaps the biggest conundrum in the management of tandem lesions is whether or not to stent the cervical ICA in the acute setting. Given the risk of dual antiplatelet therapy, especially in patients who received tPA and have larger cores, some interventionalists choose to defer in the acute setting and offer stenting versus endarterectomy later. If stenting is offered in the acute setting, it is unclear whether cervical ICA stenting should be done before or after intracranial ET. Furthermore, the role of angioplasty and the optimum antithrombotic regimen have yet to be determined. There is limited data available to help guide these decisions. While many of the ET trials included patients with tandem lesions, the management was highly variable. Tandem lesions were present in 32% of MR CLEAN, 18% of REVASCAT, and 17% of ESCAPE, while they were excluded from SWIFT PRIME and EXTEND IA. An analysis of the 30 patients with tandem lesions that were treated with ET in ESCAPE showed 17 underwent cervical ICA stenting, 10 before and 7 after intracranial ET. Of the 13 for which stenting was deferred in the acute setting, only 4 underwent ICA revascularization later.
By strokeblog|March 13th, 2019|clinical, treatment|0 Comments
Aristeidis H. Katsanos, MD, PhD
Sharma M, Hart RG, Connolly SJ, Bosch J, Shestakovska O, Ng KKH, et al. Stroke Outcomes in the COMPASS Trial. Circulation. 2019;139:1134–1145.
The Cardiovascular OutcoMes for People using Anticoagulation StrategieS (COMPASS) is a double-blind randomized clinical trial, which assigned a total of 27,395 participants with stable coronary artery or peripheral artery disease to receive either aspirin 100 mg once daily or rivaroxaban 5 mg twice daily or rivaroxaban 2.5 mg twice daily plus aspirin. Stroke occurrence during a mean follow-up of 23 months was reduced to 0.5% in the rivaroxaban 2.5 mg BID plus aspirin group (HR=0.58, 95%CI: 0.44-0.76, p<0.0001), while no significant difference was noted in the occurrence of stroke in the rivaroxaban 5 mg BID group (HR=0.82, 95%CI: 0.65-1.05) compared to aspirin monotherapy. Interestingly, the incidence of hemorrhagic stroke was significantly increased in the rivaroxaban 5mg BID group compared to the aspirin alone group (HR=2.70, 95%CI: 1.31-5.58, p=0.005), but no increase in the risk of hemorrhagic stroke was found for the combination of rivaroxaban 2.5 mg BID with aspirin group (HR=1.49, 95%CI: 0.67-3.31, p=0.33). The annualized rate of disabling or fatal stroke (modified Rankin Scale scores 3-6) was also found to be reduced in the rivaroxaban 2.5 mg BID plus aspirin group (HR=0.58, 95%CI: 0.37-0.89, p=0.01).
#STROKE Utility and validation of the #ACTFAST prehospital triage algorithm for #EndovascularThrombectomy #LVO
https://t.co/Z1uqZzUYRO https://t.co/GmGUptPSiu
►clinical (562)


text:
River Valley Film Society to debut Thursday
By Scott Smith Times Recordssmith@swtimes.com
Film: It's what makes the world go 'round and a community shine brightly.
That sentiment can be found in Brandon Chase Goldsmith, a co-founder of the recently formed River Valley Film Society, which is aiming to connect area film directors, actors, designers, producers, writers, crew members and movie fans.
"It's beyond Fort Smith; that is why we named it the River Valley Film Society," Goldsmith said. "We want to include the whole River Valley region, from Poteau down to Russellville. We want people to think of the society and the community as an area, like Northwest Arkansas, that way, when we start doing things, people will think of it in a regional sense, instead of just one city."
The River Valley Film Society will host its inaugural meeting today at 6 p.m. at 5 Star Productions, 100 N. Eighth St. The event is open to the public and will feature the screening of two locally produced movies, "Alfonso's Gold" and "Batman: The Scheme is Sound," as well as Q&A sessions and more.
"What makes these two film pieces so cool is, they demonstrate this aspect of what the River Valley Film Society is doing," Goldsmith said. "Kevin Croxton used his school students for the 'Batman' film, and he will talk about how he was able to get people from all over the community — people helped with costumes, did set pieces, someone was able to loan him the Batmobile — to come and help him.
And the same thing for 'Alfonso's Gold,' which was done by 5 Star Productions and John McIntosh and had music by Chris Cameron" he added. "That film tells the story of Alfonso Trent, who is from Fort Smith. Having local stories like that in film is great. There are local stories to be told."
Fort Smith resident Jan Johnston agreed.
"I for one am super stoked that the River Valley Film Society is a thing that is now happening," said Johnston, who often sees two or three movies in the theater a week. "There is something great about films. I don't know how to put that into words, to be honest, but movie projects are just special. I'm thankful that there's going to be the River Valley Film Society now."
Goldsmith said he wasn't sure how many people will attend the meeting, but added that he is hoping for a large crowd.
"We have something like over 500 people who like our River Valley Film Society Facebook page, and we will have another new website, RiverValleyFilmSociety.com, that will be up and running soon," he said.
"People will be able to put their head shots, their resumes, examples of their costume designs and animation, and such on the website," Goldsmith added.
Plans call for having the River Valley Film Society to have monthly meetings to keep members informed and inspired and to greet new members, he said.
"We think we might show a film that is produced in this area at each meeting; that is what we would like to see happen," Goldsmith said.
The group, which includes co-founder Tommy Street, also hopes to begin a new film festival in March, he said.
"I want to do the film festival to bring in local talent and for people to see what people have made here," Goldsmith said. "That will be one of the main focuses of the film festival — River Valley films.
"And this is for the filmmakers and for the film fans," he added. "I want to have the networking with the filmmakers and the people who are on the nerdy side of flim, but you also can't make films unless you have people who want to watch them. Both sides work together."
Goldsmith predicted that RiverValleyFilmSociety.com will benefit members, casual fans and filmmakers who are based in other parts of the country.
"Those people from bigger cities can check the site and say, 'Hey, this person works in this field, so we can hire them instead of bringing in someone from out of state,'" he said. "That is main drive behind this. This is to create a community so we can start working on projects and growing the film culture here."
Goldsmith currently is working on his "Western District" documentary and is hoping that "many" film projects continue or begin in the near future in the region.
"On working on my documentary, I kept running into people who would say, 'Hey, I'm a sound engineer,' 'I'm a costume designer' and 'I'm an actor,'" he said. "A lot of people were offering to help out in the community, but at that time, no one knew each other."
Goldsmith said those encounters are what inspired him to form the River Valley Film Society with Street.
"We don't want our area to get left out," Goldsmith said. "I mean, Little Rock has their film festival, and there's things happening in Northwest Arkansas, but people are doing really cool stuff in the Fort Smith region now. The River Valley Film Society will allow more people to know each other and create great collaborations."


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Getting screwed while doing work using woods? It is because you are ignoring some basic safety tips that avoid the repetitive fear of hand being cut by a sharp blade. Improvising or neglecting safety measures are the major cause of construction site accidents. Carpentry can be a joyful hobby in leisure time, creating a structure utilizing own ideas when completed gives a sense of pleasure and proud. Patience should be preferred while cutting the woods. If you are a professional carpenter, it means your living is tied to this work. Surely, you do not want to cut your hand that may take many days to recover, be careful not to come at this serious point. Here are some tips so simple to follow but worthy to be applied, so do what you love with safety!
Keep that in mind that you are doing a work that requires concentration and maturity. Carpentry and alcohol/drugs is a dangerous fusion. Some people drink alcohol or drugs during work to avoid any urge until they finish but you will cost more if you are under the influence of drugs or related substances.do not put yourself in danger when your co-worker doing so stop him before something tragic happens.
Preparation prior the beginning does not only related to safety but time-saving and keeps you away from distractions. Finding the relevant screw, nail or tool while the machine is running is like deliberately putting yourself in danger. To reduce the risk, check your kit for tools for the availability of all the related devices and tools. Isn't your equipment cleaned? Then its working may hinder which again push you towards self-harm.
When you forget to wear personal protective equipment, you are a few moments away from the accident. Avoid wearing loose clothes, they may stuck in the blade and you can now clearly imagine what will occur next. Always wear glasses, respirators, gloves to reduce the risks. Remove any jewelry like bracelets and rings and tie your hairs. These are simple things to do so keep your safety superior before anything else in your wood workshop.
When working with an electric saw, do not put your hands near it while it's running. Use a stick or sharp material to remove the cut-offs and debris, if there is any malfunction in the socket or plugs the saw may start when you are removing the debris with hands. Do not attempt removing the cut-offs during machine working.
This may seem like 'what?' but this dull sounded tip may help you creating with fineness and finishing. On the other hand, when you are working hard using those blunt tools, your hand will come near the blade and you will get a cut.
Alotechnical is the top class carpentry services company in Dubai. Alotechnical-carpenters in Dubai are popular for quality, finishing in work at affordable prices.


Embroidered roses set off Gucci's new Angry Cat motif, a powerful counterpoint to the GG Supreme canvas, along with crystal rays and blue suede details on a striking shoulder bag from the house's Dionysus line. Style Name: Gucci Medium Angry Cat Gg Supreme Canvas & Suede Shoulder Bag. Style Number: 5381633. Available in stores.


The Qing dynasty era ended when Taiwan was ceded to Japan 日本 with the signing of the Treaty of Shimonoseki at the conclusion of the First Sino-Japanese War in 1895. The Japanese invaded Taiwan that same year, wiping out all resistance and ushering in half a century of colonial rule.
For the purposes of this project I have chosen the neutral phrase Japanese Colonial Era 日治時代 to describe this time period but Chinese nationalists might prefer to describe it as an "occupation". The Japanese heavily developed and modernized Taiwan but not without cost to the local populace, particularly as the war effort ramped up in the 1930s. Following their defeat in World War II the Japanese were expelled from Taiwan and a new set of masters moved in. Thus began the KMT authoritarian era.


Asian, European and American influences marked Filipino culture for centuries resulting in an impressive mix charming many visitors.
From 1300 until the mid 16th century there were in the territory of the Philippines several independent sultanates of Islamic influence that practiced trade with Japan and China.
In 1521 began the colonization by the Spanish: The Philippines became part of the Kingdom of New Spain and the population was forced to convert to Catholicism.
In 1889, with Jose Rizal´s (a genius, poet, scientist and philosopher) fight for freedom and the influence of the USA, the Philippines fought the Spanish and became a USA Trust Territory. The Philippines and USA fought the Japanese alongside during World War II before obtaining full sovereignty in 1946.
During the Marcos dictatorship, this most advanced country in its region fell back to the status of third world. In 1986, the Filipinos gave an example to the world in how to get rid of a dictator and its martial law in a peaceful way. Since then, from East Germany up to Egypt many countries followed the Filipino example.
Since 1987 the Philippines are a constitutional democracy and became one of the booming Asian "Tiger countries".
Jose Rizal was a man of incredible intellectual power, with amazing artistic talent as well. He excelled at anything that he put his mind to - medicine, poetry, sketching, architecture, sociology... the list seems nearly endless.
Thus, Rizal's martyrdom by the Spanish colonial authorities while he was still very young man was a huge loss to the Philippines, and to the world at large.
Today, the people of the Philippines honor him as their national hero.
"Within a few centuries, when humanity has become redeemed and enlightened, when there are no races, when all peoples are free, when there are neither tyrants nor slaves, colonies nor mother countries, when justice rules and man is a citizen of the world, the pursuit of science alone will remain, the word patriotism will be equivalent to fanaticism, and he who prides himself on patriotic ideas will doubtless be isolated as a dangerous disease, as a menace to the social order."
This is the spirit of mind that led to his execution by the Spanish colonialist authorities, just shortly before the Philippine revolution for freedom.


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Q: How does one populate the results of an UIImagePicker with some "default" images (if the user has none of their own to choose from) How does one populate the results of an UIImagePickerController with some "default" images. In this case I have made a photo manipulation app where the user selects an image from their library, but I'd like to give them sample images without actually saving them to their libraries. Is there some way to manually inject my default images in to the the UIImagePicker?

A: The UIImagePickerController displays what is included in the camera roll.
Are you proposing that there might be a way to also include some images from your bundle when picking from the camera roll? As I do not believe this is the case.  You are seeing a copy of the camera roll when using this.
The only way I can see that this will work is that before loading the UIImagePickerController, you write the images from your application bundle to the camera roll.
Upon exiting, delete the images from the camera roll unless it was selected.
This way if they want, the users can select your image and you remove it from the library should they not choose it.
The UIImagePickerController is showing you a representation of the camera roll, so this is the only approach I can imagine would work, and is possibly not ideal.

redpajama_set_name: RedPajamaStackExchange


Find out how the Drew Bezanson signature Sano Brake Line came to be from the man himself along with some really dope riding from all over the world in this new product feature.
Sano Brakes, The only thing that can stop Drew B.
The Drew Bezanson signature Sano Brakes are CNC machined from 6061 aluminum and feature low profile arms and spring adjustors for better chain and tire clearance. They also include the Shadow machined cable hanger and ultra soft brake pads that work on any rim surface or color.
The Sano Lever is forged from 6061 aluminum and is available in small or medium sizes for maximum comfort. Hinged clamp for easy installation and a recessed bolt to protect your thumb from cuts.


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Premi e riconoscimenti
1942: BFJA Award - Best Actress
1943: BFJA Award - Best Actress
1968: Padma Shri Award
1976: Dadasaheb Phalke Award

Filmografia parziale
Joydev, regia di Jyotish Bannerji (1926)
Rishir Prem, regia di Jyotish Bannerji (1931)
Prahlad, regia di Priyanath Ganguly (1932)
Manmoyee Girls School, regia di Jyotish Bannerji (1935)
Vidyapati, regia di Debaki Bose (1937)
Mukti, regia di Pramathesh Chandra Barua (1937)
Sathi, regia di Phani Majumdar (1938)
Street Singer, regia di Phani Majumdar (1938)
Lagan, regia di Nitin Bose (1941)
Path Bendhe Dilo, regia di Premendra Mitra (1945)
Raj Lakshmi, regia di Premendra Mitra (1945)
Mej Didi, regia di Ajay Kar (1950)
Asha, regia di Haridas Bhattacharya (1956)
Indranath Srikanta O Annadadidi, regia di Haridas Bhattacharya (1959)

Altri progetti

Collegamenti esterni


If you're looking to view your daily sales in your Shopify store, visit your Analytics > Reports tab or you can visit your Orders > All Orders tab and filter by your date range.
For the email report that you need, I'd have a look at the free daily Email Reports Shopify app or look at the Data Export app and DeepMine app for more comprehensive, custom daily report emails of all your Shopify sales data.
Posted in 🤔 Advice and tagged apps, reporting, shopify.


Here are some sites that I reference during the course of my work, or just enjoy reading.
HTML5 Forms—have a field day!
A listing of free fonts sent to me by some young Web developers in the NorthWest Homeschool Group - thanks kids, and it's cupcakes all round, Ms. Amy!
Fonts Used in Business—sent to me by the students of teacher Courtney Phillips - high fives to all and remember, kids, typography sets the tone in every document you create! Thanks for sending.


Mladá Boleslav, 29 November 2018 – Czech street artist Chemis has given the ŠKODA SCALA an extravagant camouflage look. The new compact model, which celebrates its world premiere in Tel Aviv in a week, became a tourist magnet at Lennon Wall near Charles Bridge in Prague.
What seems like a normal urban graffiti area has its own story and is named after John Lennon. The singer was a hero of Czechoslovakian youth because, during communism in former Czechoslovakia, western music was banned. Since that time, the colourful wall of street art in Malá Strana in Prague, has been a symbol of the importance of one's own opinion and the courage to express one's convictions freely. Czech street artist Chemis and New York-based photographer and influencer Dave Krugman, who have combined the symbolism of this place in a surprising way with the new ŠKODA SCALA, met here to create a spectacular video. They gave the new compact model the leading role in a unique piece of street artwork.
In addition to the video, you can also find photos and interviews with the protagonists on ŠKODA Storyboard.


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Head of Research Centre "Global Commons and Climate Policy", Kiel Institute for the World Economy
Email: wilfried.rickels@ifw-kiel.de
Tel.: +49(0)431-8814-408
European Emission Trading
Negative Emission Technologies and Climate Engineering
Short-windedness Would Weaken Effective Climate Policy
KCG Journal Articles
Authors: Wilfried Rickels, Sonja Peterson (Environmental and Resource Economics, 2020, 76: 447–517)
Committing to rigid shutdown measures to contain the spreading of the corona virus has been undertaken on the tacit assumption that these measures will be temporary and can be loosened when the COVID-19 infection rates decrease and discontinued altogether once vaccines are available. Mitigating climate change and achieving ambitious temperature targets as set out in the Paris Agreement require a long-term structural change taking us away from our current carbon-intensive economy to a zero-carbon and then net-negative carbon economy[...]
(Mis)conceptions about Modelling Negative Emission Technologies
Authors: Wilfried Rickels, Christine Merk, Fabian Reith, David P. Keller, Andreas Oschlies (Environmental Research Letters, 2019, 14(10), Article: 104004)
Intentionally removing carbon from the atmosphere with negative emission technologies (NETs) will be important to achieve net-zero emissions by mid-century and to limit global warming to 2 °C or even 1.5 °C (IPCC 2018). Model scenarios that consider NETs as part of mitigation pathways are still largely restricted to afforestation and bioenergy with carbon capture and storage (BECCS), while the '[f]easibility and sustainability of [NETs] use could be enhanced by a portfolio of options deployed at substantial, but lesser scales, rather than a single option at very large scale' (IPCC 2018, p 19)[...]
Five Senior Fellows Joined KCG in June 2020
The "Kiel Centre for Globalization (KCG)" has since 2016 focused on analysing the benefits and limitations of global value chains (GVCs). These have grown in scale and complexity over the past decades. Combining expertise from economics, management science and ethics, the KCG looks at these issues from an interdisciplinary perspective[...]


Key Fobs make checking IN/OUT much easier and faster. Issue Key Fobs to Volunteers, Faculty & Staff, Vendors, Volunteers and even frequent and "trusted" visitors. Add an RFID Reader (scanner) to your School Check IN system and now users can check in/out by scanning their Key Fob. Using Key Fobs speeds the entire check in/out process because Key Fobs eliminate many button clicks and users no longer need scroll a list to find and then select their name. With Key Fobs, it's so automatic and easy.


0%101°82°Sunny with a high of 101 °F (38.3 °C). Winds variable at 6 mph (9.7 kph).Night - Clear. Winds variable at 3 to 6 mph (4.8 to 9.7 kph). The overnight low will be 79 °F (26.1 °C).
0%100°85°Partly cloudy today with a high of 100 °F (37.8 °C) and a low of 85 °F (29.4 °C).
Today - Sunny with a high of 101 °F (38.3 °C). Winds variable at 6 mph (9.7 kph).


text:
The limits of the productivist regime: capturing three decades of East Asian social policy development with fuzzy sets
Nan YANG, Stefan KÜHNER
Department of Sociology and Social Policy
Research output: Other Conference Contributions › Presentation
Systematic accounts of East Asian government responses to the
'limits of productivist regimes' (Gough, 2004) remain surprisingly rare.
Employing set-theoretic methods, this paper develops three distinct types of
East Asian welfare development, i.e. quantitative, type-specific, and radical. It then uses these types to analyse six policy fields, including education, health care, family policy, old age pensions, public housing, and passive LMP, in six East Asian societies, including China, Hong Kong, Japan, Korea, Singapore and Taiwan. We find that all cases with the exception of Hong Kong and Singapore have experienced at least one radical shift in their welfare models over the past three decades (1990-2016). East Asian governments have increasingly combined quantitative expansion/retrenchment of 'productive' and 'protective' policy structures but have done so in unique ways. South Korea has followed the most 'balanced' approach to welfare development and stands out as the best candidate for further type-specific expansions moving forward.
Published - 2 Jul 2019
The 16th Annual Conference of East Asian Social Policy Research Network: East Asian Welfare Futures: Between Productivism and Social Investment - National Taiwan University, Taipei, Taiwan, Province of China
Duration: 2 Jul 2019 → 3 Jul 2019
https://welfareasia.org/archives/368
The 16th Annual Conference of East Asian Social Policy Research Network
ESAP2019
productivist welfare capitalism
welfare state typologies
set-theoretic methods
Fingerprint Dive into the research topics of 'The limits of the productivist regime: capturing three decades of East Asian social policy development with fuzzy sets'. Together they form a unique fingerprint.
Social Policy Social Sciences
welfare Social Sciences
regime Social Sciences
Hong Kong Social Sciences
family policy Social Sciences
public housing Social Sciences
pension Social Sciences
YANG, N., & KÜHNER, S. (2019). The limits of the productivist regime: capturing three decades of East Asian social policy development with fuzzy sets. The 16th Annual Conference of East Asian Social Policy Research Network, Taipei, Taiwan, Province of China.
YANG, Nan ; KÜHNER, Stefan. / The limits of the productivist regime: capturing three decades of East Asian social policy development with fuzzy sets. The 16th Annual Conference of East Asian Social Policy Research Network, Taipei, Taiwan, Province of China.
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YANG, N & KÜHNER, S 2019, 'The limits of the productivist regime: capturing three decades of East Asian social policy development with fuzzy sets', The 16th Annual Conference of East Asian Social Policy Research Network, Taipei, Taiwan, Province of China, 2/07/19 - 3/07/19.
The limits of the productivist regime: capturing three decades of East Asian social policy development with fuzzy sets. / YANG, Nan; KÜHNER, Stefan.
2019. The 16th Annual Conference of East Asian Social Policy Research Network, Taipei, Taiwan, Province of China.
T1 - The limits of the productivist regime: capturing three decades of East Asian social policy development with fuzzy sets
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AU - KÜHNER, Stefan
N2 - Systematic accounts of East Asian government responses to the'limits of productivist regimes' (Gough, 2004) remain surprisingly rare.Employing set-theoretic methods, this paper develops three distinct types ofEast Asian welfare development, i.e. quantitative, type-specific, and radical. It then uses these types to analyse six policy fields, including education, health care, family policy, old age pensions, public housing, and passive LMP, in six East Asian societies, including China, Hong Kong, Japan, Korea, Singapore and Taiwan. We find that all cases with the exception of Hong Kong and Singapore have experienced at least one radical shift in their welfare models over the past three decades (1990-2016). East Asian governments have increasingly combined quantitative expansion/retrenchment of 'productive' and 'protective' policy structures but have done so in unique ways. South Korea has followed the most 'balanced' approach to welfare development and stands out as the best candidate for further type-specific expansions moving forward.
AB - Systematic accounts of East Asian government responses to the'limits of productivist regimes' (Gough, 2004) remain surprisingly rare.Employing set-theoretic methods, this paper develops three distinct types ofEast Asian welfare development, i.e. quantitative, type-specific, and radical. It then uses these types to analyse six policy fields, including education, health care, family policy, old age pensions, public housing, and passive LMP, in six East Asian societies, including China, Hong Kong, Japan, Korea, Singapore and Taiwan. We find that all cases with the exception of Hong Kong and Singapore have experienced at least one radical shift in their welfare models over the past three decades (1990-2016). East Asian governments have increasingly combined quantitative expansion/retrenchment of 'productive' and 'protective' policy structures but have done so in unique ways. South Korea has followed the most 'balanced' approach to welfare development and stands out as the best candidate for further type-specific expansions moving forward.
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KW - welfare state typologies
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KW - social investment
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M3 - Presentation
T2 - The 16th Annual Conference of East Asian Social Policy Research Network
YANG N, KÜHNER S. The limits of the productivist regime: capturing three decades of East Asian social policy development with fuzzy sets. 2019. The 16th Annual Conference of East Asian Social Policy Research Network, Taipei, Taiwan, Province of China.


Deciding to invest on which technology is to use for your business is very difficult, you should be the one responsible for innovation and growth within your company, but also don't want to be failed in the project. So, is an investment on ERP software worth the risk? To solve out, you need to know the benefits of ERP, and specifically how ERP system advantages and disadvantages breakdown when compared against each other and major thing is that who will provide the best ERP software?
Whether your business is large or small, there are lots of benefits of ERP software your business could gain. Enterprise resource planning software is a platform of customizable applications that allow businesses to integrate and manage their most important processes.
Scaling up your business? Do it right with ERP.
An ERP application helps to come out of the business issues, a business will grow high but this is no denying a fact that the success of any business comes with several associated issues. If your business not having an effective ERP system, it is not possible to handle different processes and their growing demands will, in the least, become confused. There will be many different things to solve in an organization to solve those issues easily an ERP system is a must. If sales team will miss out on essential customer information that has been updated recently, this means missed targets, so if you don't want to miss your customers then implement an ERP system to your business.
Every business has two extremely essential assets, they are information and data. Security of the data and integrity is highly important to ensure that strategic business information is processed and accessed by the right people. With the help of an ERP application system, while the data is maintained safely, access of data can also be given only to people who have the authority and also, strategic information will be maintained at one place while updates to such information can be done by one or more authorized people.
As a business grows it is highly impossible to manually calculate sales margin, profit ratios, information of clients and other such metrics, and measurements and performance metrics help in evaluating business progress and also help in setting future goals of your business. An ERP solution brings a degree of automation to the business by allowing employees across the organization to access shared data without the need to maintain manual records. This also enables generation of synchronized reports on key metrics of your business. Immediate access to information is remarkable to take timely decisions. Today's ERP software systems are flexible, robust, and configurable and they are not a one-size-fits-all proposition but can be sewed to the unique needs of your business. ERP systems also can adapt to the each and every changes in needs of a growing business and it is never ending, ensuring you won't have to purchase an advanced solution once your needs change or your business grows.
Having too many processes to handle? Consider integrating them all.
As the business grows, its processes will also expand. Each and everything of these processes is usually hosted on various platforms and run with various applications or software programs. This will bring a degree of complexity when it comes to the handling of similar information by your employees from various departments. In such a case, your account team handles certain software for recording income and expenses whereas the sales team uses completely different software to record sales, which actually form an integral part of your income leading to the redundancy of data and other issues. An ERP application system integrates different processes that are necessary to run a business enterprise into one single database. These processes will include inventory and order management, human resources, accounting, customer relationship management (CRM), among others. By slicking all the processes into one effective system, an ERP provides your business with a shared database that supports multiple functions across your business enterprise.
A business usually struggles with its accounting procedures if they are still either manual or if the sales, finance, accounting, and HR departments do not have access to shared data. As the business grows, these problems will also grow. Financial reporting and everyday accounting will particularly require a huge amount of time and effort which can be easily reduced or eliminated with the use of an ERP software solution. Using ERP software solution to integrate and analyze financial information will improve employee productivity and reduce delays considerably.
Customer satisfaction is the priority with ERP.
ERP gives more important to keep your customers satisfied while managing your business sales and inventory efficiently can be a herculean task if you have your customer and inventory data housed on different platforms.ERP software system can help you to report product-related data to your clients and maintain up-to-date information and will also facilitate real-time updating of all data. This can help client's representatives' access accurate, updated data and deal with your customers efficiently.
If you decide to invest in a traditional ERP, you could easily end up spending five figures for a single license this is the biggest disadvantages of ERP. The upfront cost of the software alone can be restrictively high, especially for small-to-medium-sized businesses. These businesses can avoid the upfront costs with a cloud solution, which typically can be paid for on a monthly basis.
Investing in software is high; the implementation process can cost nearly four times as much. You will need to hire additional IT staff, software training specialists, ERP consultants, etc. Vendors offering traditional ERP systems typically charge a fee for maintenance on top of the license fee.
Customization is one of the major aspects of ERP, but it can easily and quickly get out of hand. Customizing your ERP software will take more time, effort, expertise and money. But too often, businesses completely underestimate how many resources are needed and either doesn't finish their customization or end up going way over the budget.
ERP software solutions provide lots of capabilities, but that also means the software will be complex and difficult to use. It's not unheard of for a business to get clean up in all the potential of an ERP but fail to plan properly for its implementation.
When taking a decision about which platform is right for your business, it's important to consider the pros and cons of ERP software system, but an effective ERP solution offers strategic management to the business while providing operational support to the management for integrating different departments and handling with the different fluctuations and changes that take place within the them. Your businesses IT management becomes very simple with ERP.
how our erp application is better than otherwhat does erp do for your businessWhat is ERP? Which Type of Business must have an ERP Application?


text:
Man dies doing famous Victorian ocean swim, Lorne Pier to Pub
By 9News Staff
10:56am Jan 13, 2019
A man has died swimming in a popular ocean race in Victoria.
Grandfather Murray Howard, 65, was pulled from the water at 3pm yesterday while taking part in the Lorne Pier to Pub event along the famous Great Ocean Road.
Mr Howard, a cattle farmer from Beeac in the state's west, was a well-respected community member and a fan of health and fitness.
Lorne Pier to Pub claims to be the biggest ocean swim of its kind in the world. (Nine)
But tragically, lifesavers couldn't revive him yesterday.
Lorne Surf Life Saving Club issued a statement saying the club was saddened by the tragic death.
Grandfather Murray Howard, 65, was pulled from the water at 3pm yesterday while taking part in the Lorne Pier to Pub event along the famous Great Ocean Road. (Nine)
"The Lorne Surf Life Saving Club is saddened to hear of the passing of a 65-year-old male competitor at Lorne Pier to Pub, despite the best efforts to revive him from lifesavers and paramedics," the statement read.
"Our thoughts are with the family and friends of the competitor."
Victoria braces for more wild weather, as bushfire continues to burn north of Melbourne
Flash-flood warning for Victoria after storm 'supercell' smashes Melbourne
Hail, flooding as thunderstorms lash Vic
Lorne Pier to Pub claims to be the biggest ocean swim of its kind in the world.
The swim is a 1.2km course starting at the Lorne Pier and finishing on the foreshore in front of the Lorne Surf Lifesaving Club house.
The average time is takes to complete it is 22 minutes.