Somehow, despite having been there from the very beginning – when The New Cross sampler was given away free and wasn't £60 on e-bay – I've not managed to write anything about either the New Cross scene or Angular Records. I've tried hard, but there just isn't that much to say about an agglomeration of disparate bands. So it was with a small measure of excitement that I travelled to Goldsmiths Student Union for the launch of the first Angular single.
The lonely unknown outcast, the sick perverted strange.
We externalise all evil so that we can sleep at night.
Send Oedipus off to Broadmoor to serve his twenty-five.
These lines are spat out with a renewed confidence, with Ian Paisley-style contempt for the world of tabloids. On their superb new song, The Male Gaze, they turn their attention to the inescapably electro-pop themes of alienation, voyeurism and inadequacy. Jamie Manners does that 'boy with his nose pressed up against the sweetshop window pose so well, it would mean if the world didn't give him a bag of penny chews. But one suspects his time is yet to come.
One person on whom the male gaze was firmly glued was the singer of the Violets, who has gone from being nervous and sedentary (at the second Angular event) to being utterly at ease with her position as an object of leering. It's still difficult to hear what words she is singing, but her voice is strong. Guitarist, Joe Daniels, is also quite dashing in drainpipe trousers, pencil tie, black shirt and white-banded, black trilby. Even the drummer looks swish. My only qualm is with the music. Whether it is due to the lack of a bassist, I don't know, but there the songs are a too claustrophobic at the moment; there's no space between the instruments, no space for humour. Only on Feast on You, their single, do they really let go of their inhibitions. With Alex screaming and dancing and tying herself up in the microphone cord, they even inspire the kidz (admittedly students) to dance, which is a first.
Joe from The Violets asks us to listen to The Fucks and buy their single with the understandable anxiety of a man who, as Angular records co-founder, has invested his own money in it. He needn't have worried. The Fucks are naïve and charming enough to sell snow to the Eskimos, or, at the very least, irony to the students. They bestride the stage with the ease and humour of people who have a loving audience in front of them, playing their whimsical boy-girl guitar and Yamaha keyboard indie pop with tongue firmly in cheek.
Since I last saw them they've got a lot rockier, wigging out occasionally, with shoeless Jemma head- banging for all she's worth. Their amiable amateurishness suits the angular philosophy well: this is indie without pretensions to compromised success. Doubtless, the Angular boys could have capitalised on the current interest in talentless garage rock, instead they have followed their hearts.


text:
Q: get_file(fname, origin=_URL, extract=True) not extracting the file My code:
import matplotlib.pyplot as plt
import numpy as np
import os
import tensorflow as tf
from tensorflow.keras.preprocessing import image_dataset_from_directory

import os
os.environ['KMP_DUPLICATE_LIB_OK'] = 'TRUE'
os.environ['TF_CPP_MIN_LOG_LEVEL'] = '2'

_URL = 'https://storage.googleapis.com/mledu-datasets/cats_and_dogs_filtered.zip'
dl_fname = '/Volumes/D/PythonCode/tf_transfer_learning/cats_and_dogs.zip'
path_to_zip = tf.keras.utils.get_file(dl_fname, origin=_URL, extract=True)

I can see cats_and_dogs.zip being downloaded, however, it is not extracted/unzipped. I am on MacOS, using PyCharm.
I am not sure why not. Anyone has a pointer? Thanks.

A: The URL is https://storage.googleapis.com/mledu-datasets/cats_and_dogs_filtered.zip but you saved it as cats_and_dogs.zip. When you extract it, you get a directory cats_and_dogs_filtered, no matter what the name of the zip file is.
Though it does seem that the extracted file is in ~/.keras/datasets/cats_and_dogs_filtered.zip even if one uses an absolute path.
import tensorflow as tf

url = 'https://storage.googleapis.com/mledu-datasets/cats_and_dogs_filtered.zip'
dl_path = "/tmp/cats_and_dogs_filtered.zip"
path_to_zip = tf.keras.utils.get_file(dl_path, origin=url, extract=True)

The zip file is saved to the absolute path, but the extracted path goes to ~/.keras/datasets/cats_and_dogs_filtered/.
print(path_to_zip)
# /tmp/cats_and_dogs_filtered.zip

redpajama_set_name: RedPajamaStackExchange


text:
Rivals Take Aim at the Software Company SAS - NYTimes.com
IBM – and other market dynamics – threaten SAS's utopian employment model
The competitive thrust that really grabbed SAS's attention came in late July, when I.B.M. announced that it planned to pay $1.2 billion for SPSS, a maker of predictive modeling software. I.B.M. has placed SPSS and Cognos into a new business analytics and optimization group. That business will be supported by 200 scientists, and the company has said it will retrain or hire 4,000 consultants and analysts to work in the group.
"This is the big growth strategy for I.B.M., the company's next big play for this decade," says Ambuj Goyal, a computer scientist who is general manager of I.B.M's business analytics software unit. "SAS comes from the legacy world of statisticians and programmers. The real opportunity is in deploying this technology broadly in corporations."

redpajama_set_name: RedPajamaCommonCrawl


text:
Home » News » AEW News and Rumors » Saraya on Trolling Fans In the Ring at AEW Full Gear
Saraya on Trolling Fans In the Ring at AEW Full Gear
(Photo Credit: ScottLesh.com)
The recent AEW Full Gear pay-per-view saw Saraya make her long-awaited return to the ring with a win over Britt Baker. Saraya recently spoke with Dean Muhtadi (aka Mojo Rawley) of TMZ Sports and commented on how AEW Produce Jerry Lynn approached her after the match and asked about why she had her head down a lot. Saraya revealed that she was winded.
"When it came to the wrestling side of things [her in-ring return], the thing that I was worried about was if my wind was gonna get me through and it did but I was dying," she said. "Everyone was really fantastic. Jerry Lynn was backstage, he's like this old school wrestler and legend and he was like, 'You kept your head down a lot. You need to pick it up' and I was just like, 'Bro, I couldn't keep my head up. I was blown up.' I could not breathe. I was face down. I was like, I could not believe I went out and did that. I think we did a total of 14 minutes and the first initial thing was everyone was really excited I was in the ring, right? So they're very hyped."
Saraya continued and revealed how she trolled fans with her first bump in the match.
"So then I did the first bump and I wanted to do that first bump where I was like, I psyched everybody out because everyone was like, 'As soon as she takes the first bump, she's gonna break her neck,' because it's really crazy to me that people were so supportive of the men coming back but I don't know if it's a female thing or not and I don't wanna make it about that really but coming back, there was a lot of mixed reactions about it," she said. "People were supportive or they were just really mean to me and I'm like, what is happening? Shouldn't this be a really cool thing for people to witness? So I wanted to go out there and prove everybody wrong but also troll them a little bit with the first bump. So I decided to act and pretended like I hurt my neck and everyone went dead quiet in the arena. They went like [gasped] and then I got up and just started laughing, you know?
"And then the crowd went quiet again because after that, all the bumps, they were all just like, oh my God, please don't get hurt and I realized afterwards it's just because people genuinely don't want me to get hurt in the ring again. It's a scary situation and there was that viral video of me getting hurt in the first place so I understood and once I got through it, everyone was clapping afterwards like, whew. She got through it you guys. Good job."
There's no word yet on when Saraya will return to the ring but she is advertised for most upcoming AEW tapings. She spoke with Renee Paquette on Friday's AEW Rampage and made it known she wants the AEW Women's World Title, currently held by Jamie Hayter.
Stay tuned to WrestlingHeadlines.com for more.
(H/T to POST for the quotes)
AEW Dark Reportedly Returning to Universal Studios
WWE Announces Two Triple Threats with High Stakes for Tonight's RAW


text:
Sergeant Rev. George Bryce was born on a farm near Mount Pleasant, Ontario, on 22 April 1844, a year after his parents had immigrated to Canada from Scotland. He received what was, for the times, a good education, at the high school in nearby Brantford, the University of Toronto, and Knox College, where his success as a student was marked with medals and scholarships. He was an athlete, playing on the college football team.
He had served in The Queen's Own Rifles of Canada during the Fenian troubles of 1866 and was present at the Battle of Ridgeway with No. 9 Company.
Bryce was one of the founders and he served two terms as President of the Manitoba Historical and Scientific Society – once from 1884 to 1887, and again from 1905 to 1913. He was a prolific author, who wrote nine books and forty or fifty pamphlets as well as numerous sermons and speeches. He delivered 30 papers before the Historical and Scientific Society of Manitoba alone, on topics as diverse as geology, archaeology, and Red River history. In 1902 his scholarship gained national recognition when he was elected to the Royal Society of Canada. In 1910 he served as the Royal Society's President and he was also a member of many other learned societies. In 1920 he was awarded an honorary degree by the University of Manitoba.
As a young Presbyterian minister, Bryce was part of the influx of Ontario immigrants who came to Manitoba after the collapse of Riel's Provisional Government in 1870.
He was selected in 1871 by the General Assembly of the Presbyterian Church to come west to Red River to organize a Presbyterian college and a new church. He set up Manitoba College in the same year and taught there until 1909. In 1872 he founded Knox Church, the first Presbyterian church in Winnipeg. He was also one of the founders of the University of Manitoba, and taught science on the University faculty and served on the University Council until his retirement in 1904.
In his later years, after the death of his wife Marion Bryce, he grew frail and moved back to Ontario to live with his brother, Dr. P. H. Bryce, in Ottawa. He died there, largely forgotten, on 5 August 1931 and was buried in the Kildonan Cemetery. He is commemorated by Bryce Avenue in Winnipeg, and Bryce Hall (with a commemorative plaque) at the University of Winnipeg. There are extensive papers at the University of Winnipeg.


text:
Ban could chill isles' tourism, state attorney general says
By Dan Nakaso dnakaso@staradvertiser.com
Students, visiting professors and others from six predominantly Muslim countries with legitimate ties to the United States will be allowed to travel to Hawaii but face an uncertain future once they arrive, state Attorney General Doug Chin said Monday following a decision by the U.S. Supreme Court on President Donald Trump's travel ban. Read more
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Public's opinions welcome on Maui's new biogas facility
Monday service is set for music star Pahinui
Students, visiting professors and others from six predominantly Muslim countries with legitimate ties to the United States will be allowed to travel to Hawaii but face an uncertain future once they arrive, state Attorney General Doug Chin said Monday following a decision by the U.S. Supreme Court on President Donald Trump's travel ban.
The court agreed to hear arguments in October over two lawsuits challenging the ban, including one filed by Chin's office. But no one knows when a decision will be reached, leaving visitors with legitimate U.S. connections from Libya, Iran, Somalia, Sudan, Syria and Yemen in limbo once they arrive.
"If I were to put myself in the shoes of those people — or, really, anybody outside of the United States who's watching everything that's happened — there's no question that what has happened has created a chilling effect," Chin told reporters Monday following the Supreme Court's ruling. "It's created uncertainty in the United States as far as who's going to be allowed to come into the country."
And that uncertainty could spill over into countries beyond the six listed under Trump's ban, Chin said.
The Attorney General's Office argued "that the problem with having these sort of temporary bans is that it makes people who are even not from these countries wonder whether or not it's going to be OK for them to come into the United States," Chin said.
While the court's decision temporarily allows entry to students and others with legitimate U.S. ties, it'll make it more difficult for tourists from the six countries with no U.S. connections to visit Hawaii and other U.S. destinations, Chin said.
He cited Hawaii tourism data from two years ago in which 6,200 island visitors came from the Middle East and 2,000 more from Africa.
Trump tweeted Monday that the Supreme Court's decision was a "clear victory."
But Chin said, "I would say it's a victory for President Trump in the sense that people for the next six months who have no ties to the United States who are from the six Muslim majority nations aren't going to be able to come into the United States. But by the flip side, I could say it's a victory for our position in the sense that people who do have a connection to the United States who are from those six Muslim majority nations … are not covered by the travel ban."
The court's decision is a victory for Ismail Elshikh, the imam of the Muslim Association of Hawaii, who is a plaintiff in the Hawaii case because his mother-in-law is a Syrian national living in Syria.
While Elshikh, his wife and their five children are U.S. citizens, his mother-in-law wants to visit the family in Hawaii that represents her U.S. connection.
"He's grateful for this decision," Chin said. "I think he is pleased that this executive order is not going to apply to him."
But, Chin said, "The bottom line is his mother-in-law still isn't here, which is very unfortunate."


The API is simple. All that's needed to create a graphic is to specify a few default parameters and then, if desired, override one or more of the optional parameters on offer. The library is data-source agnostic. While it provides a number of convenience functions and options that allow for graphics to better handle things like missing observations, it doesn't care where the data comes from.


text:
NaturalGas.org
The Market Under Regulation
The current regulatory environment in which the natural gas industry operates is much less stringent and relies more heavily upon competitive forces than in the past. The last twenty years have seen dramatic changes throughout the industry, spurred by its ever-changing regulatory environment. However, despite the restructuring and deregulation of some portions of the natural gas supply chain, there still exist significant regulatory oversight of the industry in the transportation and distribution of natural gas. This oversight is necessary to ensure that those market participants that possess monopoly power in the industry do not abuse this power or distort the smooth and efficient functioning of the natural gas markets. To jump ahead in this section, click on the links below:
Overview of Current Regulation
Regulation of Distribution
FERC – Regulation of Interstate Pipelines
FERC Processes
Some Important FERC Regulations and Orders
Under the current regulatory environment, only pipelines and local distribution companies (LDCs) are directly regulated with respect to the services they provide. Natural gas producers and marketers are not directly regulated. This is not to say that there are no rules governing their conduct, but instead there is no government agency charged with the direct oversight of their day to day business. Production and marketing companies must still operate within the confines of the law; for instance, producers are required to obtain the proper authorization and permitting before beginning to drill, particularly on federally-owned land. However the prices they charged are a function of competitive markets, and are no longer regulated by the government.
Interstate pipeline companies, on the other hand, are regulated in the rates they charge, the access they offer to their pipelines, and the siting and construction of new pipelines. Similarly, local distribution companies are regulated by state utility commissions, which oversee their rates, construction issues, and ensure proper procedure exists for maintaining adequate supply to their customers.
Source: NGSA
The current regulation of transportation pipelines by the Federal Energy Regulatory Commission (FERC) has designated that interstate pipelines can serve only as transporters of natural gas. In the past, interstate pipelines acted as both a transporter of natural gas, as well as a seller of the commodity, both of which were rolled up into a bundled product and sold for one price. However, since FERC Order 636, interstate pipelines are no longer permitted to act as merchants and sell bundled products. Instead, they can only sell the transportation component, and never take ownership of the natural gas themselves. Pipelines must also now offer access to their transportation infrastructure to all other market players equally, referred to as 'open access' to the pipelines. This allows marketers, producers, LDCs, and even end users themselves to contract for transportation of their natural gas via interstate pipeline, on an equal and unbiased basis.
The current regulatory environment is the product of many years of regulatory evolution. To review the history of natural gas regulation in the United States, click here.
This section will focus on the regulation of the natural gas industry by the Federal Energy Regulatory Commission (FERC). FERC has jurisdiction over the regulation of interstate pipelines and is concerned with overseeing the implementation and operation of the natural gas transportation infrastructure. FERC obtains its authority and directives in the regulation of the natural gas industry from a number of laws; namely the Natural Gas Act of 1938, the Natural Gas Policy Act of 1978, the Outer Continental Shelf Lands Act, the Natural Gas Wellhead Decontrol Act of 1989, and the Energy Policy Act of 1992.
Because FERC obtains its direction and authority from legislation, it is important to get an overview of important congressional committees and government departments that have jurisdiction over areas affecting the natural gas industry, as well as power to direct the future regulation of the industry. To view links to these committees, departments, and agencies charged with oversight of varying aspects of the natural gas industry, click here.
The regulation of local distribution companies has much the same objective as regulation of intestate pipelines, including avoiding the exercise of market power, protecting customers who rely on their supply of natural gas from a single source (captive customers), and ensuring that the rates and prices set by an LDC are fair and equitable. State regulatory utility commissions have oversight of issues related to the siting, construction, and expansion of local distribution systems. Although these general objectives generally hold across states, there are different processes and regulations in place across the country. For more information on the regulation of natural gas distribution, visit the National Association of Regulatory Utility Commissioners here.
Regulation of distribution is currently undergoing a process of change, with the adoption by many states of programs aimed at exploring and instituting retail choice programs. These programs allow natural gas consumers more flexibility in arranging the delivery of their gas, including allowing many customers the option of purchasing their own natural gas, and using the distribution network of their LDC simply to transport that gas. For more information on the status of retail choice programs and unbundling of LDC services across the country, visit the Energy Information Administration here.
The Federal Energy Regulatory Commission is an independent regulatory agency charged with the regulation of certain aspects of the energy industry in the United States, including the regulation of natural gas transportation. It was created in 1977 under the Department of Energy Organization Act. Although a government agency, FERC is designed to be independent from any undue political party influence or affiliation, as well as independent from any influence from the executive or legislative branches of government, and industry participants, including the energy companies over which it has oversight.
FERC is composed of five commissioners, who are nominated by the President of the United States, and confirmed into office by the U.S. Senate. Each commissioner serves a five year term, and one commissioner's term is up every year. The President also designates one of these commissioners to act as FERC Chariman, who has the responsibility for setting a biweekly commission agenda. FERC operates by majority rule, which means that any Order must be approved by at least three of the five commissioners. FERC also has a significant staff, which is responsible for administrative functions, as well as conducting research and advising the commissioners on important matters. There are approximately 1,150 FERC staff, of which 400 focus on electric industry issues, 325 focus on hydro power issues, and 425 concentrate on oil and natural gas issues.
FERC oversees those industries in which member companies have significant market power over their sectors; for example natural gas pipelines are considered 'natural monopolies' due to the fact that in many areas, a single pipeline infrastructure has control over all of the transportation of natural gas to that area. FERC is charged with regulating to ensure that companies do not abuse these monopoly positions; and its regulatory objectives include:
Preventing discriminatory or preferential service
Preventing inefficient investment and unfair pricing
Ensuring high quality service
Preventing wasteful duplication of facilities
Acting as a surrogate for competition where competition does not or cannot exist
Promoting a secure, high-quality, environmentally sound energy infrastructure through the use of consistent policies
Where possible, promoting the introduction of well functioning competitive markets in place of traditional regulation
Protecting customers and market participants through oversight of changing energy markets, including mitigating market power and ensuring fair and just market outcomes for all participants
In the natural gas industry, FERC regulates the rates and services offered by interstate pipeline companies, as well as certifying and permitting new pipeline construction and some closely related environmental issues. In order to build new pipelines, or expand existing infrastructures, pipeline companies must show to FERC how the new or expanded pipeline will serve the public interest, that it is economically feasible, and that it does not have significant environmental impacts. The certification of new pipeline developments is required under Section 7 of the Natural Gas Act. To learn more about the certification process, visit the FERCs website here.
There are essentially two types of issues faced by FERC: making company specific decisions, and making industry-wide decisions. Company specific issues can include applications for rate changes for one company's transmission services, applications for changes in terms or conditions of transportation contracts, and complaints filed by another industry member, including utilities, project sponsors, trade associations, or any other interested party.
The process for dealing with a company specific issue is relatively straightforward. An application or complaint is filed (whether it is an application to expand a pipeline, construct a new one, or a complaint concerning unfair rates) to FERC. This filing is publicly posted, so that interested parties may have time to research and develop comments or viewpoints that they believe may help (or serve their purposes) in the decision making process. FERC staff members typically perform an analysis of the matter, and issue recommendations to the Commission. After FERC staff has reviewed the issue, it is time for the Commission to take action. FERC has fairly wide discretion with how it may decide to resolve issues; it may just make a decision without any further procedures, it may hold a trial-type hearing before an Administrative Law judge, or hold a technical conference or 'paper' hearing. Alternate dispute resolution, like mediation and arbitration, may also be used. For minor matters, the power to make a decision may be delegated to a FERC staff member (usually an Office Director). However, whatever the process used, the Commission has the final say; although FERC decisions may be appealed in the Federal Court of Appeals.
Industry wide issues and decisions may be much more complicated than company specific issues. Because issues and regulations that affect the entire industry are being contemplated, the number of interested parties can be very high, and countless opposing viewpoints may exist. It is the job of FERC to consider all different points of view, and issue a decision based on what it believes is the best course of action for the industry in general.
FERC first addresses industry wide matters by issuing a Notice of Inquiry (NOI), or a Notice of Proposed Rulemaking (NOPR). Notices of Inquiry are generally intended to indicate that FERC is collecting information, ideas, and opinions regarding a certain matter. Notices of Proposed Rulemaking are generally intended to indicate the proposition of new regulations or policy changes. After issuing a NOI or NOPR, FERC then seeks comments from interested parties; essentially giving industry members, the public, trade associations, and any other interested parties the chance to explain their position to FERC. FERC then reviews and considers these comments before making a final decision. The final outcome of this process could be to issue an NOPR (after issues have been clarified under a NOI) to propose new regulations or policy changes, or to issue new regulations or policy changes (that were earlier proposed under a NOPR), usually in the form of a FERC Order, policy statement, or rulemaking. FERC also has the option of abandoning the initiative altogether.
Important FERC Regulations and Orders
There are several important regulations which serve to shape the current regulation of interstate pipelines. Below is a brief description of a few FERC Orders that impacted the way in which interstate pipelines conduct business. This is by no means a comprehensive list of major FERC policy statements and Orders, but instead provide a brief overview of a couple of important Orders. To learn more about recent FERC actions in relation to the natural gas industry, visit FERCs website here.
FERC Order 636 – 1992
FERC Order 636 involves the restructuring of interstate pipeline services. The main objectives of this order include:
Requiring interstate pipelines to 'unbundle' their service, essentially separating the sale of natural gas from the transportation. Under FERC Order 436, pipeline unbundling was voluntary; Order 636 made it mandatory
Allows FERC to issue blanket certificates which allow pipelines to offer unbundled services for firm or interruptible service at market-based rates
Allows for abandonment options for interruptible and short term firm transportation, and in certain instances longer term firm transportation services
Sets a generic capacity brokering program for pipelines to release excess capacity (which includes setting rate ceilings for the sale of released capacity)
For more information on FERC Order 636, visit the FERC website here.
FERC Order 637 involves the regulation of short term pipeline services, and the regulation of interstate pipelines. Essentially, this order served to address some of the issues that had arisen after six years of operating under Order 636, and revise the regulatory structure in response to increased competition in the natural gas industry, and in the transportation of natural gas. Some important aspects of this order include:
Suspended price ceilings for the sale of short term (less than one year) released capacity until September 30, 2002 (to respond to the formation of a significant 'gray market' in the sale of bundled capacity during peak periods by marketers and LDCs that essentially circumvented the ceilings set by Order 636)
Changes the regulations regarding scheduling procedures, capacity segmentation, and the penalties imposed on pipelines in order to improve competition and efficiency in the interstate transportation of natural gas
Removes economic biases associated with the right of first refusal for pipeline services, while at the same time protecting the ability of captive customers (with no other options for meeting their natural gas supply needs) to resubscribe to long-term transportation capacity
Improves the reporting requirements, allowing for more transparency in market pricing and allow for more effective monitoring of the industry
This order involved the regulation of the movement of natural gas in the Outer Continental Shelf (OCS) of the United States, under the Outer Continental Shelf Lands Act. This order was intended to ensure that the transportation of natural gas from facilities located on the OCS was offered on a non-discriminatory, open access basis. Some important issues in this Order include:
The establishment of a regulatory regime for the Outer Continental Shelf that provides for greater market transparency similar to the regulation of interstate pipelines, requiring all
Dictates that all gas service suppliers on the OCS are subjected to the same regulatory environment, whether they fall under the jurisdiction of the Natural Gas Act (interstate pipelines) or not
Sets reporting requirements for OCS gas service providers, requiring that the provider disclose information regarding the facilities it operates, its affiliates, existing customer contracts or information on its conditions of service and rates charged, although there is currently legal dispute as to whether FERC has the power to demand the reporting of certain sensitive information
This allows FERC to ensure that service is non-discriminatory, particularly with respect to affiliates of gas service providers in the OCS region
NOPR – Standards of Conduct for Transmission Providers
An important issue currently facing FERC is the regulation of the interaction of transmission providers and their affiliated companies. FERC initiated discussion about the standards of conduct for transmission providers by issuing a Notice of Proposed Rulemaking in September of 2001. This proposed rulemaking deals primarily with standards for transmission providers (including interstate pipelines) dealing with affiliated companies, and the possibility that pipeline affiliated companies may receive preferential treatment, or allow pipeline companies to 'circumvent' certain regulations. Thus FERC intends to develop a clear set of regulations and rules regarding the conduct of transmission providers, particularly in their dealings with affiliated companies.
The process for setting standards of conduct for transmission providers gives a good indication of the number and range of interested parties who are concerned with FERC regulation. To learn more about this NOPR, and view the comments that have been submitted by various parties, visit the FERC website here.
The regulatory environment in which the natural gas industry operates is constantly changing, with small modifications and company specific issues being dealt with, as well as the institution and modification of broader, far reaching policy objectives and major rulemakings. In order to understand the regulatory forces that affect the natural gas industry, a constant eye must be kept on the status of regulation.
To get the most up to date information on current issues facing FERC with respect to natural gas, visit FERC's website here.
September 20, 2013 by natgas
Overview of Natural Gas
Natural Gas – From Wellhead to Burner Tip
Industry and Market Structure
Natural Gas Demand
Natural Gas Supply
Natural Gas Regulations
The History of Regulation
Environment & Technology
Natural Gas and Technology
Natural Gas and the Environment
Focus on LNG
Focus on Jobs
Potential For New Jobs
Employment By State
Focus on Shale
Shale's Growing Share
Before Shale
Shale Wells
Big Impact
Fueling Jobs and Economic Growth
Shale Shock
Water Requirements
Water Disposal Issues
Shale and Greenhouse Emissions
Natural Gas Quiz
and the Newsprint theme.


text:
Equity returns don't compensate for downside risks
One of the basic assumptions of modern finance is that equities have higher returns than bonds because they have bigger risks. The equity risk premium is generally supposed to be compensation for this increased risk. Over the years, more and more holes have been drilled into this basic assumption. Eugene Fama and Kenneth French even showed in a review article in 2004 that the relationship between systematic risk (i.e. beta) and returns is much weaker than predicted by the Capital Asset Pricing Model (CAPM).
Today we live in a world of factor investing where more than 300 factors have been identified that provide a statistically significant risk premium in violation of the CAPM. I was trained as a physicist and physicists tend to abandon a theory when it is empirically violated once. In finance, there are still people who believe in the CAPM even though it has been empirically violated hundreds of times.
Nevertheless, the advocates of modern finance continue to insist that while the CAPM might be imperfect, at least it has a grain of truth in it insofar as it postulates a relationship between risk and return. Now, Yigit Altigan and his colleagues have put this basic assumption to the most direct test I have ever seen. They took all the stocks in 26 developed equity markets and calculated a range of downside risk measures ranging from downside beta to value at risk on a monthly basis. Then, they looked at the relationship between the downside risks of stocks and the subsequent returns. If equity returns are compensation for downside risks, stocks with higher downside risks should have higher returns.
In order to test this hypothesis, they did the usual thing and split the stocks into five equal-sized buckets and measured the performance of the 20% stocks with the highest downside risks relative to the performance of the 20% stocks with the lowest downside risks. The chart below shows the result for five selected countries and the average over 26 developed markets if downside beta is used as a risk measure. Countries with statistically significant return differences are marked with an asterisk.
Equity return premium for downside beta
Source: Altigan et al. (2019).
On average, stocks with a higher downside beta had lower returns than stocks with a lower downside beta meaning that higher downside risks led to lower returns, not higher. In countries like Japan and Australia, the returns were so much lower that the difference was even statistically significant. The situation becomes even more extreme when we go further out to the tail of extreme losses. If we use Value at Risk (99%) instead of downside beta we look at only the most extreme 1% of negative events in each stock. And lo and behold, the risk premium is a risk discount in practically every country.
Equity return premium for Value at Risk (99%)
If this doesn't give you pause, then you either haven't understood finance theory or these results. They are a direct contradiction of the most basic premise of finance and indicate that we get something fundamentally wrong about finance (or that this study is completely wrong and needs to be retracted). In my book, I dedicate an entire chapter on the topic of complex dynamic systems theory and how it improves on traditional finance. In a complex dynamic systems view of financial markets, equity return no longer has to be a compensation for increased risk and the results shown above are another indication that this new view of markets may be a better model of the world than the one we currently have.


text:
require 'ohmage/api'
require 'ohmage/request'

module Ohmage
  class Client
    include Ohmage::API
    attr_accessor :port, :path, :client_string, :user, :password, :token, :server_config, :server_url, :server_debug
    def initialize(options = {}) # rubocop:disable MethodLength
      self.server_url = ENV['OHMAGE_SERVER_URL']
      self.user = ENV['OHMAGE_USER']
      self.password = ENV['OHMAGE_PASSWORD']
      self.client_string = 'ruby-ohmage'
      self.path = 'app/'
      self.port = 443
      self.server_debug = false
      options.each do |k, v|
        instance_variable_set("@#{k}", v)
      end
      yield(self) if block_given?
      server_config_read
      self
    end

    #
    # ohmage config/read call
    # @returns [Hash] of server config details
    #
    def server_config_read
      request = Ohmage::Request.new(self, :get, 'config/read', {})
      resp = request.perform
      self.server_config = resp[:data]
    end

    #
    # ohmage user/auth_token call
    # @see https://github.com/ohmage/server/wiki/User-Authentication#statefulAuthentication
    # @returns String: auth_token valid for server's auth_token_lifetime param
    #
    def auth_token
      params = {}
      params['user'] = user
      params['password'] = password
      request = Ohmage::Request.new(self, :post, 'user/auth_token', params)
      resp = request.perform
      self.token = resp[:token]
      resp[:token]
    end
    alias_method :auth, :auth_token

    # Masking password from inspected client.
    # Lovingly lifted from https://github.com/octokit/octokit.rb,
    # The full text of the license for this work (MIT) can be found at
    # http://opensource.org/licenses/mit
    # @return [String]
    def inspect
      inspected = super
      inspected.gsub! @password, '*******' if @password
    end
  end
end

redpajama_set_name: RedPajamaGithub


Retail Food Group (RFG) expects an underlying net profit after tax (NPAT) to be approximately $34.5 million for FY18, a 54 per cent decline on FY17's figure of $75.7 million.
Additionally, the company expects statutory NPAT to be a loss of approximately $87.6 million.
At the time of publication market shares have dropped by almost 6 per cent.
RFG has been plagued by scandal recently, with allegations of bad business practices, including exorbitant fees and a lack of support, driving franchisees out of business surfaced in the media.
The Group continues to "maintain dialogue with its bankers and their advisers" in regard to the expected results after concerns over whether it would breach its bank covenants.
RFG's lenders, Westpac and National Australia Bank, raised the debt to earnings ratio to 3 times from 2.5 times – hinting that the company may have been close to breaching its borrowing requirements.
The company is currently in a banker-enforced "step down program" in an effort to reduce its debt from $259.7 million, with 60 per cent of net proceeds dedicated to paying this debt for the foreseeable future.
The Statutory FY18 NPAT figure is also impacted by termination payments to former Managing Director, Andre Nell, who left the position after just two years, in May.
The position was picked up by Richard Henson, a former Metcash state manager, who joined the business in January.
RFG will provide a detailed market update with the FY18 results announcement in August 2018.
(Source by Dean Blake – Inside Retail Australia).


text:
Books that will broaden young kids' perspectives
Among these pages, they'll find a true representation of the world.
By PopSci Commerce Team | Published Dec 24, 2019 7:48 PM
We may earn revenue from the products available on this page and participate in affiliate programs. Learn more ›
In this day and age, a lot of stories told through children's books don't stand the test of time in terms of appropriateness (see the bloodiness of the original Grimm's fairy tales and problematic race stereotypes in Curious George). Luckily, there are a number of modern books that teach children about equality and fairness, and portray minorities as heroes. Here are our top picks for forward-thinking books for kids.
This 2012 winner of a Gelett Burgess Children's Book Award tells the story of a wave named Roland who's afraid of his fate once he hits the beach. As he ponders the end of his existence, he realizes he's not just a wave, but also the whole ocean. It's a compelling and beautiful metaphor for how interconnected we all are.
For kids who break out into tantrums or get easily upset, Breathe Like a Bear is an illustrated collection of mindfulness exercises. It includes 30 simple and short breathing exercises to teach kids body awareness and emotional management. They can be done at school, in car rides, and even on stressful homework nights.
Before Greta Thunberg there was Joan of Arc, Anne Frank, Cleopatra, and many others. Even though gendered toys and stereotypes are still prominent in society, there's no shortage of stories of bold and fearless women who are unafraid to challenge the status quo. This book, which tells the stories of 30 of them, is the perfect gift to inspire any tween.
A very special male bunny, Marlon Bundo (the same name as the real-life pet rabbit of vice president of the US, Mike Pence), falls in love with another male bunny. It's written by John Oliver and spreads a message of love, tolerance, and acceptance for same-sex marriage and democracy. Naturally, it's funny as well.


text:
Sardulgarh è una suddivisione dell'India, classificata come nagar panchayat, di 16.315 abitanti, situata nel distretto di Mansa, nello stato federato del Punjab. In base al numero di abitanti la città rientra nella classe IV (da 10.000 a 19.999 persone).

Geografia fisica
La città è situata a 29° 41' 60 N e 75° 15' 0 E e ha un'altitudine di 209 .

Società

Evoluzione demografica
Al censimento del 2001 la popolazione di Sardulgarh assommava a 16.315 persone, delle quali 8.778 maschi e 7.537 femmine. I bambini di età inferiore o uguale ai sei anni assommavano a 2.448, dei quali 1.340 maschi e 1.108 femmine. Infine, coloro che erano in grado di saper almeno leggere e scrivere erano 8.801, dei quali 5.148 maschi e 3.653 femmine.

Note

Centri abitati del Punjab

redpajama_set_name: RedPajamaWikipedia


elecon crusher operating manual in pdf - villasovaggio.it. Elecon Hammer Coal Crusher Operation Manual. elecon crusher operating manual in pdf, elecon hammer coal crusher operation manual YouTube Feb 11, 2014, Coal can crushed by our jaw crusher,cone crusher .
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Painting in Abaco has become almost as much of a passion to me as fly fishing in Abaco….It's getting there quickly. The sky reflects the Bahamian turquoise blue water and the water returns the favor. This is the land of bright colors softened by days and days of glaring sunlight that turns all colors into the same pastel tones.
"Incoming" is the result of a moment in time on the flats waiting for the tide to come in signaling the beginning of the bonefish tidal banquet. Bonefishing in the Bahamas is one of the great pursuits of a fishermans fishing life and trying to capture the anticipation of the event is always a challenge for the artist. A painting like "incoming" relies on the observer having experienced the "game day" butterflies, the waiting and knowing what is in store, not always sure of the outcome but hoping for the best, then counting on the feeling of success.
In progress....filling in the details.
"Incoming" is an oil on canvas painting, 20×30 inches. There are Limited Edition prints available numbered from 1 to 300 priced at $225.00 each. Numbers 1-10 are priced accordingly.


Every beautiful girl needs a milk bath! You go Claire! Enjoy the skin and share some sort of dessert with Mom! We should all count our Blessings this Thanksgiving and remember those less fortunate.
Thank you for the update. I have been checking each day, two or three times a day. How wonderful that you were able to meet Eliot's parents...God blesses us with friendships that are meaningful and I know your paths were sure to cross for this special reason. I am so excited about little Claire trying to take a bottle..what a treat! I still love the lollipop moment the best! Tomorrow is a day of giving thanks...as we all thank God for our families and blessings, we remember to thank him for Claire and for how she has affected so many lives in a positive way. We also thank God for parents like you and Billy, and for sisters like Camille. Happy Thanksgiving to you all and continue to be blessed! Give Claire and Camille my love.
Sometimes I think babies cry because they do not know how to express themselves any other way .Claire has so much to say ,and she doesn`t even know that we hear her sweet cry.
I am thankful for your family and the lessons of love you teach us .
Today's Thnaksgiving and you guys have so much too be thankful for! You have two beautiful daughters! Give thanks to the Lord for He is good! Let all creation rejoice in your gladness!
Happy Thanksgiving! I'm really glad you were able to meet Matt and Ginny. That must have been very encouraging to you guys. Do not grow weary doing good...We are praying for you.
I found your site through Eliot's a while back and check on you several times a week. I continue to pray for your family and for sweet Claire.
What an honor to meet you guys. This blog cannot contain what a precious family you guys are. It was so great to meet you in person. Claire is amazing. A weekend at the beach could not compare to five minutes of Claire.


text:
Q: How to handle backpressure in Nodejs stream split2() library? Getting heap out of memory error I am using split2 to read a huge file and get an iterable where each chunk is one line:
const downloadedFile = this._s3client.getObject(params)
const userStream: Readable = await downloadedFile.createReadStream()

for await (const userId of pipeline(userStream, split2()) {
    console.log(userId)
}

This code results into error from node engine

"FATAL ERROR: Ineffective mark-compacts near heap limit Allocation failed - JavaScript heap out of memory\n"

Any ideas where could this memory leakage could be coming from? Do I need to handle backpressure explicity here somehow?


text:
Home	Local	Traffic, Crime and Fire Blotter
LocalTraffic & Crime Blotter
by Mitchell White December 19, 2020 0 comment
SM police investigating homicide
SANTA MARIA —The Santa Maria Police Department is investigating a homicide that occurred Friday night on West Donovan Road.
Police responded to a report of a shooting in the 800 block of West Donovan Road shortly before 4:30 p.m. Upon arrival, authorities located a deceased victim, police said.
Detectives were on scene and actively investigating the shooting on Friday night.
No arrests have been made.
— Mitchell White
Man arrested on gun, drug charges
Numerous illegal drugs were seized following the service of the search warrant, including eight pounds of methamphetamine, one ounce of brown heroin, one ounce of tar heroin, and several grams of fentanyl. Authorities also seized several hundreds of rounds of ammunition and six firearms, including two assault rifles and a suppressed handgun.
LOMPOC — A Lompoc man was arrested earlier this week and is facing several drug and firearm charges, authorities said.
On Thursday, detectives from the Santa Barbara County Sheriff's Office Special Investigations Bureau served narcotics-related search warrants at residences in the 400 block of Capella Drive and the 200 block of Briar Creek Way in Lompoc, said Raquel Zick, sheriff's spokeswoman.
Detectives seized illegal drugs as a result, including eight pounds of methamphetamine, one ounce of brown heroin, one ounce of tar heroin, and several grams of fentanyl.
In addition, authorities seized several hundreds of rounds of ammunition and six firearms, including two assault rifles and a suppressed handgun, Ms. Zick said.
John Carothers, 59, was arrested on suspicion of possession of methamphetamine for sale, possession of heroin for sale, possession of fentanyl for sale and numerous felony gun charges. The felony charges include possession of a firearm, possession of ammunition, possession of an assault weapon and possession of a silencer.
Mr. Carothers was booked at the Main Jail and is being held on $300,000 bail.
Man arrested in SM shooting
SANTA MARIA — A Guadalupe man was arrested Thursday in connection with a shooting that occurred Monday night and left one man in critical condition, police said.
Detectives with the Santa Maria Police Department's Special Enforcement team served arrest and search warrants in Santa Maria, Guadalupe and Tanglewood on Thursday related to its investigation. Justin Orozco, 19, was arrested without incident on suspicion of attempted murder. He is being held on $1M bail, according to a department news release.
The shooting was reported around 7:30 p.m. Monday in the 200 block of West Williams Street. A man was transported to Marian Regional Medical Center and is listed in critical condition, police said.
An investigation is ongoing. Members of the public with any information on this crime can contact Detective Robbins at 805-928-3781 ext. 1361 or the tip line at 805-928-3781 ext. 2677.
No arrests made in probation wellness checks
Earlier this week, authorities conducted county-wide wellness checks on active probation clients, which yielded 30 contacts and zero arrests, authorities said.
The checks were conducted Thursday by the Santa Barbara County Probation Department in collaboration of the Office of the District Attorney, Victim Services Division. The operation focused on probationers where it was determined there were children, victims, or vulnerable adults in the home, said Karyn Milligan, spokeswoman for the county Probation Department.
The cases included incidents of domestic violence, child abuse, elder abuse, family violence, and where there was a child likely residing in the home. The operation covered the Santa Barbara, Santa Maria, Orcutt, Lompoc, and Goleta areas, Ms. Milligan said.
The operation included an assessment of the living environments, documentation of any needs of the probationer or family members, and a way to provide information on probation and community resources and to ensure client compliance with their terms and conditions of probations.
Wellness bags were handed out to each family and children, which included facemasks, hand sanitizer, sanitizing cloths, first aid kits, thermometers, stress balls and brochures for community resources. The child wellness bags were holiday themed and included popcorn, coloring books, crayons, puzzles and candy canes.
A total of 36 locations were visited and 30 contacts were made with no arrests. A total of 43 wellness bags were distributed.
Taking part in the operation were 20 deputy probation officers and three victim advocates from the District Attorney's Office.
Mitchell White
Construction to begin on Cathedral Oaks Road repair project
County reports first pediatric COVID-related death


On Feb. 3, the University of Vermont Board of Trustees approved a cross-college, Master of Science degree program in food systems, after more than three years of extensive planning and discussion.
The effort, begun in 2009 when UVM received a USDA Higher Education Challenge Grant for the creation of the program, gained steam in 2010 when Food Systems was chosen as one of UVM's Transdisciplinary Research Initiatives (TRI). Along with complex systems and neuroscience, behavior and health, food systems has been identified as a key area of research investment across the disciplines.
"This is a vehicle in which numerous partners … can really engage, and put UVM and the state of Vermont in the forefront of how we actually create a change in the local and regional food system," John Bramley, interim president, said at the board meeting.
The program has already begun the work of connecting with partners external to the university. Community Development and Applied Economics professor Jane Kolodinsky and Nutrition and Food Sciences professor Amy Trubek, co-authors of the program's proposal, consulted with more than 400 organizations outside of UVM during the writing process.
Rachel Johnson, professor of nutrition and food sciences and a member of the program's steering committee, believes that its approval will help UVM gain ground in the academic food systems community. "The approval of this masters program is very exciting and puts UVM at the leading edge of the emerging field of food systems," she said.
Now that the program has been approved, next steps include accepting students' applications for the fall 2012 semester and furthering the research. "Now, the real work begins," Kolodinsky said.
Published online by the Food Systems Spire on 02/06/2012. Read it here.


text:
Human Proteome Folding Project, projecte interuniversitari per a l'estudi de les formes de les proteïnes humanes
 Fons de Preservació Històrica (del seu nom en anglès Historic Preservation Fund), fons del Servei de Parcs Nacionals per a la conservació dels llocs històrics dels Estats Units
 High Performance Fortran, extensió del Fortran que permet computació paral·lela
 Filtre passaalt (del seu nom en anglès High-Pass Filter), filtre electrònic que permet el pas de les freqüències altes
 Camp d'alta potència (del seu nom en anglès High-Power Field), secció visible per microscopi usada en diagnòstic de citologia
 HPF també és l'abreviatura d'hores post-fertilització, unitat de mesura utilitzada en biologia del desenvolupament


The Grand Mufti of Australia, Dr Ibrahim Abu Mohamed, was the keynote speaker at the Iftar Dinner hosted by the Uniting Church and the Affinity Intercultural Foundation at Parramatta Mission on 14 June. This is his speech.
I start by expressing my gratitude and appreciation to my friends, the President of the Australian Uniting Church, Stuart McMillan, Reverend Michael Barnes and his team for their kind invitation, Affinity, Jeremy Spinak President of the NSW Jewish Board of Deputies, Local Police, Local MP's Community and Faith Leaders.
It is an absolute pleasure to be with you all this evening, and to be able to build bridges of peace and understanding in our blessed multicultural country.
Respected guests, I would also like to apologise for not being able to communicate effectively in the English language. But I would like to stress that my religion, Islam, has afforded me a heart that loves all creation of God and language will not limit my ability to convey that message.
If we consider the human condition and all the pain and suffering around us today, we can highlight many challenges that stand out.
But one that stands out to all of us is the hijacking of religion to suit a warped ideology.
History tells us that any religion that is hijacked by a deviant minority will stain it with their depravity. Islam and the rest of the world have now fallen victim to this evil and despite our advanced civilisation, we still see a wounded, bleeding society, weighed down by extremism and hatred with an insatiable hunger for destruction. It is heart wrenching that the result of this evil is the indiscriminate killing of innocent men, women and children under weak justifications.
All the divine prophets have declared Glory to God in the highest heaven, and on earth peace to those on whom his favour rests. However we see a minority who over the ages have aimed to undermine our happiness and to force their madness upon the world.
Islam, as we have learned and recognised in its divine essence is an institution of humanity, culture, civilisation, a safeguard for human intellect, freedom, and an upholder of those rights. It flows forth from a wholesome source, and is a paradigm of justice and equality. It serves to build this world and counter disease and poverty and everything that denies mankind their dignity.
It favours peace over war, and security over violence and terrorism. It calls the mind to contemplate and ascend, and the heart to believe and be at peace.
We have to maintain our belief that the power of the mind is more powerful than any weapon, and that our values can overcome any evil, and that our efforts for peace must be greater than extremism and hatred.
God's Messenger (ﷺ) said, "Both in this world and in the Hereafter, I am the nearest of all people to Jesus, the son of Mary. The prophets are paternal brothers; their mothers are different, but their religion is one."
In this holy text, the Noble Quran binds all humanity together in the bonds of brotherhood and sisterhood, regardless of their religion. It asks all people to maintain kind relationships, if not for the sake of religion then it should be for the sake of humanity.
In such a call to people, the Quran goes beyond the limits of history and geography, which have divided people. These divisions have created wars, where innocent blood has been shed.
Religions, in their pure form encourage a positive discourse, build bridges and promote tolerance.
Ladies and Gentlemen: thank God that in spite of the hatred we encounter there are still Australians who have the ethos of love and awareness. Whose seeds were sown by all the prophets, especially by our beloved prophets, Moses, Jesus and Muhammad, peace be upon all of them. It is our duty now to maintain their positive messages and promote the common values of all religions.
This is the message that has been communicated to us, so why do we deviate from the path?
Love is the key to changing hearts, minds and entire societies. The message of our faiths is clear, in that to be in the service of others is the quickest route to spreading love. This is the duty of all Australians, to serve each other and promote love and harmony to continue to grow in our cultural richness. Let us make Australia the leading nation in promoting mutual love in the context of our multicultural landscape.
We emphasise that terrorism and racism are two sides of the same coin. We must remain united in confronting these evils, and we must not let anything weaken our determination to protect Australia. I remind our leaders that Australia needs their positive discourse; a discourse that builds bridges rather than walls, and protects diversity.
At this point, I would like to stress the importance of faith leaders coming together in the spirit of cooperation. I would like to thank every person who supports social cohesion, justice, love and mutual respect.
We pray for peace to prevail across the world. May God protect Australia and all Australians, and may He purify us from the plagues of extremism, hatred, and racism.
May the peace and blessings of God be with you all.


text:
Nitric oxide synthase and changes in oxidative stress levels in embryonic kidney observed in a rabbit model of intrauterine growth restriction
Horacio Figueroa, Jorge Cifuentes, Mauricio Lozano, Cristobal Alvarado, Claudia Cabezas, Elisenda Eixarch, Ellio Fernández, Luis Contreras, Sebastián Illanes, Edgar Hernández-Andrade, Eduard Gratacós, Carlos Ernesto Irarrazabal Muñoz*
Programa de Fisiología
Grupo de Fisiología Integrativa
Objective: This work aimed to study the effect of uteroplacental circulation restriction on endothelial kidney damage in a fetal rabbit model. Methods: New Zealand rabbits were subjected to 40% to 50% of uteroplacental artery ligation at day 25 of pregnancy. After 5 days, surviving fetuses were harvested by cesarean section. The gene and protein expressions of selected enzymes associated with nitric oxide production and oxidative stress were analyzed in fetal kidney homogenates. Results: The placenta weight (6.06 ± 0.27, p < 0.0319) and fetal body (19.90 ± 1.03, p < 0.0001) were significantly reduced in the uteroplacental circulation restriction group. The kidneys from restricted fetuses presented a mild vascular congestion and glomerular capillary congestion, without inflammation or hypertrophy. We found endothelial nitric oxide synthase phosphorylation inhibition (0.23 ± 0.13, p < 0.012) and arginase-2 (0.29 ± 0.14, p < 0.023) protein induction in fetal kidneys of the circulation restriction group. Finally, the kidneys from circulation-restricted fetuses showed increased inducible nitric oxide synthase messenger RNA (mRNA) (2.68 ± 0.24, p < 0.01) and reduced heme oxygenase-1 mRNA (23 ± 1.3, p < 0.003), with increased reactive oxygen species (1.69 ± 0.09, p < 0.001) and nitrotyrosine protein (1.74 ± 0.28, p < 0.003) levels, without changes in Nox mRNA. Conclusion: We describe significant deregulation of vascular activity and oxidative damage in kidneys of fetal rabbits that have been exposed to restriction of the uterine circulation.
https://doi.org/10.1002/pd.4829
© 2016 John Wiley & Sons, Ltd.
10.1002/pd.4829
Dive into the research topics of 'Nitric oxide synthase and changes in oxidative stress levels in embryonic kidney observed in a rabbit model of intrauterine growth restriction'. Together they form a unique fingerprint.
Fetal Growth Retardation Medicine & Life Sciences 100%
Nitric Oxide Synthase Medicine & Life Sciences 88%
Placental Circulation Medicine & Life Sciences 66%
Oxidative Stress Medicine & Life Sciences 66%
Rabbits Medicine & Life Sciences 64%
Fetus Medicine & Life Sciences 54%
Renal Circulation Medicine & Life Sciences 53%
Figueroa, H., Cifuentes, J., Lozano, M., Alvarado, C., Cabezas, C., Eixarch, E., Fernández, E., Contreras, L., Illanes, S., Hernández-Andrade, E., Gratacós, E., & Irarrazabal Muñoz, C. E. (2016). Nitric oxide synthase and changes in oxidative stress levels in embryonic kidney observed in a rabbit model of intrauterine growth restriction. Prenatal Diagnosis, 36(7), 628-635. https://doi.org/10.1002/pd.4829
Figueroa, Horacio ; Cifuentes, Jorge ; Lozano, Mauricio ; Alvarado, Cristobal ; Cabezas, Claudia ; Eixarch, Elisenda ; Fernández, Ellio ; Contreras, Luis ; Illanes, Sebastián ; Hernández-Andrade, Edgar ; Gratacós, Eduard ; Irarrazabal Muñoz, Carlos Ernesto. / Nitric oxide synthase and changes in oxidative stress levels in embryonic kidney observed in a rabbit model of intrauterine growth restriction. In: Prenatal Diagnosis. 2016 ; Vol. 36, No. 7. pp. 628-635.
@article{bac8c7faa3094501a3c38c0fd9d119e2,
title = "Nitric oxide synthase and changes in oxidative stress levels in embryonic kidney observed in a rabbit model of intrauterine growth restriction",
abstract = "Objective: This work aimed to study the effect of uteroplacental circulation restriction on endothelial kidney damage in a fetal rabbit model. Methods: New Zealand rabbits were subjected to 40% to 50% of uteroplacental artery ligation at day 25 of pregnancy. After 5 days, surviving fetuses were harvested by cesarean section. The gene and protein expressions of selected enzymes associated with nitric oxide production and oxidative stress were analyzed in fetal kidney homogenates. Results: The placenta weight (6.06 ± 0.27, p < 0.0319) and fetal body (19.90 ± 1.03, p < 0.0001) were significantly reduced in the uteroplacental circulation restriction group. The kidneys from restricted fetuses presented a mild vascular congestion and glomerular capillary congestion, without inflammation or hypertrophy. We found endothelial nitric oxide synthase phosphorylation inhibition (0.23 ± 0.13, p < 0.012) and arginase-2 (0.29 ± 0.14, p < 0.023) protein induction in fetal kidneys of the circulation restriction group. Finally, the kidneys from circulation-restricted fetuses showed increased inducible nitric oxide synthase messenger RNA (mRNA) (2.68 ± 0.24, p < 0.01) and reduced heme oxygenase-1 mRNA (23 ± 1.3, p < 0.003), with increased reactive oxygen species (1.69 ± 0.09, p < 0.001) and nitrotyrosine protein (1.74 ± 0.28, p < 0.003) levels, without changes in Nox mRNA. Conclusion: We describe significant deregulation of vascular activity and oxidative damage in kidneys of fetal rabbits that have been exposed to restriction of the uterine circulation.",
author = "Horacio Figueroa and Jorge Cifuentes and Mauricio Lozano and Cristobal Alvarado and Claudia Cabezas and Elisenda Eixarch and Ellio Fern{\'a}ndez and Luis Contreras and Sebasti{\'a}n Illanes and Edgar Hern{\'a}ndez-Andrade and Eduard Gratac{\'o}s and {Irarrazabal Mu{\~n}oz}, {Carlos Ernesto}",
note = "Publisher Copyright: {\textcopyright} 2016 John Wiley & Sons, Ltd.",
doi = "10.1002/pd.4829",
journal = "Prenatal Diagnosis",
Figueroa, H, Cifuentes, J, Lozano, M, Alvarado, C, Cabezas, C, Eixarch, E, Fernández, E, Contreras, L, Illanes, S, Hernández-Andrade, E, Gratacós, E & Irarrazabal Muñoz, CE 2016, 'Nitric oxide synthase and changes in oxidative stress levels in embryonic kidney observed in a rabbit model of intrauterine growth restriction', Prenatal Diagnosis, vol. 36, no. 7, pp. 628-635. https://doi.org/10.1002/pd.4829
Nitric oxide synthase and changes in oxidative stress levels in embryonic kidney observed in a rabbit model of intrauterine growth restriction. / Figueroa, Horacio; Cifuentes, Jorge; Lozano, Mauricio; Alvarado, Cristobal; Cabezas, Claudia; Eixarch, Elisenda; Fernández, Ellio; Contreras, Luis; Illanes, Sebastián; Hernández-Andrade, Edgar; Gratacós, Eduard; Irarrazabal Muñoz, Carlos Ernesto.
In: Prenatal Diagnosis, Vol. 36, No. 7, 01.07.2016, p. 628-635.
T1 - Nitric oxide synthase and changes in oxidative stress levels in embryonic kidney observed in a rabbit model of intrauterine growth restriction
AU - Figueroa, Horacio
AU - Cifuentes, Jorge
AU - Lozano, Mauricio
AU - Alvarado, Cristobal
AU - Cabezas, Claudia
AU - Eixarch, Elisenda
AU - Fernández, Ellio
AU - Contreras, Luis
AU - Illanes, Sebastián
AU - Hernández-Andrade, Edgar
AU - Gratacós, Eduard
AU - Irarrazabal Muñoz, Carlos Ernesto
N1 - Publisher Copyright: © 2016 John Wiley & Sons, Ltd.
N2 - Objective: This work aimed to study the effect of uteroplacental circulation restriction on endothelial kidney damage in a fetal rabbit model. Methods: New Zealand rabbits were subjected to 40% to 50% of uteroplacental artery ligation at day 25 of pregnancy. After 5 days, surviving fetuses were harvested by cesarean section. The gene and protein expressions of selected enzymes associated with nitric oxide production and oxidative stress were analyzed in fetal kidney homogenates. Results: The placenta weight (6.06 ± 0.27, p < 0.0319) and fetal body (19.90 ± 1.03, p < 0.0001) were significantly reduced in the uteroplacental circulation restriction group. The kidneys from restricted fetuses presented a mild vascular congestion and glomerular capillary congestion, without inflammation or hypertrophy. We found endothelial nitric oxide synthase phosphorylation inhibition (0.23 ± 0.13, p < 0.012) and arginase-2 (0.29 ± 0.14, p < 0.023) protein induction in fetal kidneys of the circulation restriction group. Finally, the kidneys from circulation-restricted fetuses showed increased inducible nitric oxide synthase messenger RNA (mRNA) (2.68 ± 0.24, p < 0.01) and reduced heme oxygenase-1 mRNA (23 ± 1.3, p < 0.003), with increased reactive oxygen species (1.69 ± 0.09, p < 0.001) and nitrotyrosine protein (1.74 ± 0.28, p < 0.003) levels, without changes in Nox mRNA. Conclusion: We describe significant deregulation of vascular activity and oxidative damage in kidneys of fetal rabbits that have been exposed to restriction of the uterine circulation.
AB - Objective: This work aimed to study the effect of uteroplacental circulation restriction on endothelial kidney damage in a fetal rabbit model. Methods: New Zealand rabbits were subjected to 40% to 50% of uteroplacental artery ligation at day 25 of pregnancy. After 5 days, surviving fetuses were harvested by cesarean section. The gene and protein expressions of selected enzymes associated with nitric oxide production and oxidative stress were analyzed in fetal kidney homogenates. Results: The placenta weight (6.06 ± 0.27, p < 0.0319) and fetal body (19.90 ± 1.03, p < 0.0001) were significantly reduced in the uteroplacental circulation restriction group. The kidneys from restricted fetuses presented a mild vascular congestion and glomerular capillary congestion, without inflammation or hypertrophy. We found endothelial nitric oxide synthase phosphorylation inhibition (0.23 ± 0.13, p < 0.012) and arginase-2 (0.29 ± 0.14, p < 0.023) protein induction in fetal kidneys of the circulation restriction group. Finally, the kidneys from circulation-restricted fetuses showed increased inducible nitric oxide synthase messenger RNA (mRNA) (2.68 ± 0.24, p < 0.01) and reduced heme oxygenase-1 mRNA (23 ± 1.3, p < 0.003), with increased reactive oxygen species (1.69 ± 0.09, p < 0.001) and nitrotyrosine protein (1.74 ± 0.28, p < 0.003) levels, without changes in Nox mRNA. Conclusion: We describe significant deregulation of vascular activity and oxidative damage in kidneys of fetal rabbits that have been exposed to restriction of the uterine circulation.
U2 - 10.1002/pd.4829
DO - 10.1002/pd.4829
JO - Prenatal Diagnosis
JF - Prenatal Diagnosis
Figueroa H, Cifuentes J, Lozano M, Alvarado C, Cabezas C, Eixarch E et al. Nitric oxide synthase and changes in oxidative stress levels in embryonic kidney observed in a rabbit model of intrauterine growth restriction. Prenatal Diagnosis. 2016 Jul 1;36(7):628-635. https://doi.org/10.1002/pd.4829


Thank you for visiting our website. This page provides information about the Free School applications that Arthur Mellows and the Fulbridge Academy are submitting to the Department for Education to build 2 new schools at Paston Reserve; one primary school and one secondary school. These schools are being built to meet the need for new school places for students from the Paston Reserve development currently being built and also to provide for the predicted shortage of school places across Peterborough in the future. Both schools will be members of the Four Cs Academy Trust which is a Multi-Academy Trust formed by Arthur Mellows (secondary) in partnership with the Fulbridge Academy (primary).
The new secondary school, called Manor Drive Academy (secondary phase) is due to open in September 2021 with Year 7 only. Initially it will have 5 forms of entry, rising to 8 forms of entry in subsequent years. It will have a Sixth Form opening in 2024. The school will share a lot in common with Arthur Mellows; its values, its standards and its aspirations for learning and student's achievement.
We are still at an early stage in our design and planning but we will update this webpage with additional information as it becomes available. Please find below links to relevant policies and documentation.


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The Intangible Cultural Heritage Fund will support safeguarding priorities in four countries in Africa and Latin America
28 October 2016 Botswana, El Salvador, Kenya, Seychelles,
The Seychelles launched its first International Assistance project
Seychelles,
© Julienne Barra
The Seychelles recently began implementing its first International Assistance project, granted within the framework of the Intangible Cultural Heritage (ICH) Fund. By its Decision 11.COM 3.BUR 5.3, the Bureau of the Intergovernmental Committee for the Safeguarding of the Intangible Cultural Heritage approved the allocation of a total sum of US$90,000 from the ICH Fund to the Seychelles for a project entitled 'Strengthening capacity in Seychelles for safeguarding intangible cultural heritage'.
The first activity of this project was a three-day workshop on the implementation of the 2003 Convention for the Safeguarding of the Intangible Cultural Heritage. The aim of the workshop was to raise awareness among decision makers, non-governmental organizations and community representatives about the purpose of the 2003 Convention, with a view to ensuring its implementation in the Seychelles. Two experts, who are members of the ICH Global Network of Facilitators – Mrs Deirdre Prins-Solani and Mr Lovemore Mazibuko – facilitated the workshop. The participants, who are all potential stakeholders in the implementation of the 2003 Convention in the Seychelles, were selected from different sectors and parastatals.
The key issues that emerged from the workshop were the need to engage the community in the safeguarding of ICH, develop strategies to implement the 2003 Convention and methods to ensure its effective implementation nationwide. Participants engaged in intensive discussions about the implications of safeguarding ICH nationally for the wellbeing of communities, respect and understanding between communities, cultural diversity and sustainable development.
Seychelles signed and ratified the 2003 Convention on 15 February 2005.
International assistance:
Strengthening capacity in Seychelles for safeguarding intangible cultural heritage for sustainable development (2016)


OpenGL functionality in After Effects CS6 is different from OpenGL functionality in previous versions. This document is only for After Effects CS4 through CS5.5. For more information about After Effects CS6 GPU functionality, see this video.
Adobe After Effects crashes or closes without an error while it starts.
A crash or freeze when you scrub the timeline or preview or render a composition.
A crash when you change the settings of an effect while OpenGL previews are enabled.
A crash or freeze when you enable or disable OpenGL previews.
The composition window takes a long time to redraw.
Artifacts or blocks of "garbage" pixels are drawn in the composition window.
The composition window is drawn differently between when OpenGL previews are on and off.
" After Effects warning: A problem occurred when processing OpenGL commands."
"The instruction at '0x00fe1940' referenced memory at '0x000000000' The memory could not be 'read'."
"AE_OpenGL: failed to generate shadow map (5065::0)"
"This composition is too complex for the OpenGL hardware."
"After Effects error: AE_OpenGL: Create texture error. (5065 :: 0)"
For information about how to configure the preview preferences in After Effects for OpenGL and a list of features in After Effects that can be rendered with OpenGL, see Render with OpenGL in After Effects Help.
To benefit most from this document, perform the tasks in order. Record the tasks that you perform and the results of each, including errors and other problems. Adobe Technical Support can use this information to better assist you if you call.
It's necessary to log on as an administrator to perform some of the procedures in this document.
For Windows, some of these procedures require you to locate hidden files and hidden folders. Some procedures require you to locate files by their full filenames, which include extensions (for example, example_filename.ini). By default, Windows Explorer doesn't show hidden files, hidden folders, and filename extensions that it recognizes. See Show hidden files and folders in Windows for details.
For Windows Vista, the steps in this document that mention the Control Panel are in reference to the Classic view. For information on switching the Control Panel to the Classic view and many other common OS procedures, see Common OS procedures.
These tasks can help you resolve the most common problems with OpenGL. Before performing any of these tasks, back up all personal files (for example, After Effects files you created). Always restart the computer after a system error occurs to refresh its memory. Continuing to work without restarting the computer can compound the problem.
To check for updates, choose Help > Updates in After Effects.
2. Make sure that the computer system meets the minimum requirements for After Effects.
3. Make sure that the video card and drivers meet the OpenGL requirements.
Using OpenGL in After Effects requires an OpenGL card that supports OpenGL 2.0.
To determine what version of OpenGL your card supports, click the OpenGL Info button in the Preview preferences. On Mac OS, choose After Effects > Preferences > Previews. On Windows, choose Edit > Preferences > Previews.
For information regarding supported OpenGL hardware, see GPU (CUDA, OpenGL) features.
Newer video card drivers can improve the OpenGL capabilities of your card. See Update the video card driver below.
4. Disable OpenGL to determine whether it is causing the problem.
Choose After Effects > Preferences > Previews (Mac OS) or Edit > Preferences > Previews (Windows).
Deselect the Enable OpenGL option.
Note: OpenGL does not support some features in After Effects, and the appearance of your composition can change between using OpenGL previews and software-rendered previews. For the list features that OpenGL supports, see Render with OpenGL in the Rendering and Exporting section of After Effects Help.
5. Remove the OpenGL plug-in from the After Effects plug-ins folder.
To determine if OpenGL caused the problem, remove the OpenGL plug-in and restart After Effects.
Mac OS: Drag the AE_OpenGL.plugin file from the Applications/Adobe After Effects CS4/Plug-ins/Extensions folder to the desktop.
Windows: Drag the AE_OpenGL.AEX file from the C:\Program Files\Adobe\Adobe After Effects CS4\Support Files\Plug-ins\Extensions folder to the desktop.
If the problem recurs, OpenGL didn't cause it. Drag the OpenGL plug-in back to the original location. If the problem doesn't recur, the cause of the problem is OpenGL. See Update the video card driver below.
6. Update the video card driver.
Many OpenGL problems or conflicts are solved by updating the video card driver. Many video card manufacturers frequently update their software drivers. If you haven't recently updated the video card driver, contact the video card manufacturer for an updated driver, or download one from the manufacturer's website.
Following a crash that an OpenGL problem on Windows causes, After Effects CS4 can automatically disable the Prevent DLL Address Space Fragmentation preference. This preference allows After Effects to access a larger amount of contiguous RAM, but can be incompatible with some OpenGL drivers.
You can enable or disable the Prevent DLL Address Space Fragmentation preference by going to Edit > Preferences > Memory & Cache.
Leave this preference enabled unless you are experiencing OpenGL or memory-related crashes. If you disable the preference because of an OpenGL problem, and you later update the video card drivers, reenable the preference. Then, test the problem again.
8. Optimize the Texture Memory preference.
Crashes or OpenGL errors can occur if After Effects attempts to use too much video texture memory. Texture memory is the amount of RAM on the video card (VRAM).
Multiply the total installed VRAM by 80% to calculate the optimal Texture Memory setting.
In After Effects, choose After Effects > Preferences >Previews (Mac OS) or Edit > Preferences > Previews (Windows).
Enter the value you calculated in Step 1, then click OK.
The ideal value for texture memory is 80% of the VRAM on your video card. (If you use multiple video cards, calculate 80% of the VRAM on the video card that is identified in the OpenGL Information dialog box.) If the Texture Memory preference in After Effects is set to more than 80% of the VRAM, it's possible that not enough VRAM is left for the video card to handle the user interface or other tasks. (For example, the entire screen can turn white.) If the value is set to less than 80%, OpenGL previews in After Effects can take longer to process frames.
See Mac OS Help or Windows Help for information about determining the amount of VRAM on a video card.
9. Purge the image caches and video memory.
If After Effects displays artifacts or "garbage" (blocks of incorrect pixels) in the composition window, the video memory (VRAM) could be full, fragmented, or corrupted. Purge the image caches and video memory to empty the VRAM and let After Effects rebuild the composition preview.
To purge the image caches, choose Edit > Purge > Image Caches.
To purge the video memory, choose Edit > Purge > Video Memory.
Note: Some screen savers that use OpenGL (or Direct3D on Windows) can corrupt the video memory if they activate while After Effects is running. Change or disable the screen saver if you frequently have problems with corrupted images in the composition window after turning off the screen saver.
10. Change the color setting for the video card to Highest (32 bit) (Windows) or Millions (Mac OS).
See Mac OS Help or Windows Help for information about changing the video card or display settings.
Most display card drivers include utilities that allow you to access advanced functions of the card. In particular, anti-aliasing, and 16-bit mode functions can conflict with OpenGL and cause After Effects to crash. Set the advanced functions of the card to their defaults, then disable the anti-aliasing and 16-bit mode options.
If you are using multiple monitors with an Nvidia card, set the Multimonitor setting to "Compatible".
See the documentation for the video card or to the manufacturer's website for instructions on how to access its advanced functions.
12. Use a single monitor.
If you have placed the After Effects application window or the Composition panel on a secondary monitor, move the window to the primary monitor.
Disconnect all but one monitor.
If you are using multiple display cards, remove all but one display card. For best results with OpenGL, use a single dual-head display card.
13. Place the Reduce OpenGL Texture Size script in the Startup scripts folder.
The Reduce OpenGL Texture Size script reduces the amount of texture memory After Effects uses and can provide better compatibility with older video cards.
Navigate to the After Effects scripts folder.
On Mac OS: Applications/Adobe After Effects CS4/Scripts.
On Windows: C:\Program Files\Adobe\Adobe After Effects CS4\Support Files\Scripts.
Move the Reduce OpenGL Texture Size.jsx file from the (support) folder to the Startup folder.
A newer video card can improve the OpenGL capabilities of your computer and make the script unnecessary. After you install a new card and its drivers, move the Reduce OpenGL Texture Size script back to the (support) folder. Then reset the After Effects preferences.
14. Reset After Effects preferences.
Re-create the After Effects preferences file to eliminate problems that damaged OpenGL preferences can cause.
To re-create the After Effects preferences file, restart After Effects. Hold Ctrl+Alt+Shift (Windows) or Command+Option+Shift (Mac OS) while the application is starting.
15. Contact Adobe Technical Support.
If none of the above steps has resolved the error or freeze that you are experiencing with After Effects, then contact Adobe Technical Support. You can find the support options at Adobe Support.


text:
Online Streaming: Boon or Bane to the Media Industry and Digital Rights Management?
By WhoisXML API (Sponsored Post) A Domain Research, Whois, DNS, and Threat Intelligence API and Data Provider
Copyright infringement laws have become less effective due to the ease of sharing content over the Web. Music streaming services, for example, have increased music consumption and the overall industry revenue, but it also has lessened album sales and song downloads. In 2018, song sales decreased by 28.8%, while album sales declined by 18.2% from the previous year.
Are streaming services a boon or a bane then to the media industry as a whole? Let's look at the arguments.
Boon or Bane?
Looking at the report mentioned above, we can see that:
Although the total album consumption grew by 16.2%, the actual album sales declined by 18.2%.
Despite the increase in total song consumption by 27.4%, the total song sales declined by 28.8%.
What Do the Numbers Mean?
All deserving parties do not get the correct shares of on-demand streaming service revenue. Artists and songwriters don't get paid their due, as most of the revenue goes to the large streaming companies. While the music industry has evolved, the laws governing it have remained stagnant. The current U.S. copyright law does not define interactive streaming nor state which exclusive rights it infringes upon, resulting in ambiguity and complications in proper payouts.
There are also no laws that define what licenses on-demand streaming services need to obtain. Companies argue that digital downloads only exploit mechanical rights. Online personalized noninteractive radio services, meanwhile, only require public performance licenses. Terrestrial radio broadcasts only require performance licenses for musical compositions, which means only songwriters are paid but not performers. Terrestrial broadcasting companies argued that radio provided free advertising for record labels and their artists. Only recently has it become generally accepted that interactive streaming services exploited both mechanical and public performance rights. Copyright holders are now fighting to change the detrimental guidelines that prevent artists from collecting the royalties they deserve.
Lack of standardized payment rates raises another prominent issue. While listeners may not care what platform they use to stream music, royalty rare disparities significantly affect artists and record labels. Streaming services typically pay record labels hefty fees for an umbrella license of all their songs. These rates are undisclosed, but researchers estimated sound-recording royalties per stream. These are allocated to record labels, which in turn pay even smaller amounts to artists, depending on their record deals. The artists don't even know what the negotiated royalties are between their labels and the streaming services.
Another shortcoming has to do with the Digital Millennium Copyright Act (DMCA), which was signed into law in 1998 to promote access to information and the Internet's growth. Unfortunately, while the Web continued to grow, the law didn't. The Online Copyright Infringement Liability Limitation Act (OCILLA), for instance, granted online service providers a safe harbor, absolving them of financial liability in some instances of infringement. If a provider is unaware of users transmitting, caching, storing, or linking to copyright material on its site, it can't be held liable. Providers would only be liable if they "adopt and reasonably implement a policy of terminating in appropriate circumstances the accounts of subscribers who are repeat infringers and must accommodate and not interfere with 'standard technical measures.'" As such, OCILLA effectively allows online service providers to profit off of illegal materials. The provider can claim ignorance and remove the material only once a copyright holder submitted a complaint. However, materials removed are often quickly re-uploaded, adding to the gap.
What Can Copyright Holders Do?
Digital rights management (DRM) could be an answer. It is a systematic approach to protecting copyright for digital media. It prevents unauthorized redistribution of digital media and restricts ways consumers can copy content they've purchased.
Content creators and publishers can use DRM products to curb online piracy of commercially marketed materials, for instance, through peer-to-peer (P2P) file exchange programs. These products embed code in copyrighted material to prevent copying. Some specify a period when content can be accessed or limit the number of devices media can be installed on.
One way to limit the amount of time for accessing content is by controlling how many times a song can be played depending on how much money the user paid. A user can also be limited to playing content only on a registered device. In this case, limitations can be enforced based on a user's IP geolocation. Content owners can impose limitations based on any user's unique identifier, in this case, his IP address.
Blocking the IP address of proven copyright infringers can also be imposed. They won't be able to share content illegally, after all, if they can't access it. This approach is one way to ensure that copyrighted material doesn't end up in P2P sharing platforms like torrent sites.
Although DRM is by no means a one-trick pony, it at least limits content access to the right individuals. Augmented with IP geolocation tools that can prevent unauthorized access, it would be more effective.
By WhoisXML API, A Domain Research, Whois, DNS, and Threat Intelligence API and Data Provider – Whois API, Inc. (whoisxmlapi) is a big data and API company that provides domain research & monitoring, Whois, DNS, IP, and threat intelligence API, data and tools to a variety of industries. Visit Page
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interpolator can be set to any factor from 1 to 1024 to and achieve up to 4096 angle steps per revolution. ABZ quadrature signals up to an edge rate of 16 MHz are available at the incremental outputs, permitting 200 000 rpm at the highest resolution.
The outputs are RS422 compatible with adjustable output current and slew rate. The position of the index pulse is adjustable. At pins U, V and W three electrically 120° phase shifted signals are available for the commutation of brushless DC motors with 1 to 16 pole pairs.


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Q: C# error: adding reference to .dll file I have my project file and Calculator01.dll file in same directory. When I'm trying to add a reference to Calculator.dll file message box appears and show

"A reference to 'E\IT131344............Calculato01.dll could not be added. Please make sure file is accessible and that it is a valid assembly or COM component."

I have already marked class functions with in CalDllWrapper class;
[DllImport("Calculator01.dll")]

Solutions I have found so far does not work for me. What can I do to resolve this problem? Please help me.
thanks in advance

A: You can not add references to unmanaged DLLs. Only managed DLLs can be referenced. Unmanaged DLLs can only be used by using the DllImport attribute. Please note that the application needs to be able to access the DLL.