text:
Q: Легковесные GUI-приложения Задача заключается в создании оконного приложения (Windows), имеющего небольшой размер исполняемого файла и не содержащего зависимостей от внешних библиотек. Например, если писать с использованием Qt и поместить нужные библиотеки в exe-файл, размер этого файла будет несколько десятков мегабайт.
Какие есть альтернативы для создания оконных приложений с исполняемым файлом минимального размера (хотя бы <5 Мб)? Кроссплатформенность не нужна.
UPDATE
Альтернативные фреймворки предложены в комментариях к ответу.
A: Чистый WinAPI. Можно с библиотекой MFC.
exe-шник будет динамически линковаться с необходимыми бибилиотеками, которые поставляются с Windows.
Простенькая игра с компьютерным противником, рисованием по WM_PAINT и с меню у меня занимает 128кБ (в Release-сборке).
A: "затруднительно, долго и нудно"

Это только поначалу, потом наделаешь своих модулей, и будет всё писаться быстро.
"2015 год всё же, интернет у всех быстрый."

Дело не в интернете вовсе, правильная мысль у человека. Если нужная мне программа, найденная в сети, занимает больше 2-3мб, я её не использую, ибо это говорит о криворукости программиста или лени, когда этот функционал можно было запихнуть в 500кб.
The "core" (the "hello" program compiled & linked with a static FLTK library using gcc on a 486 and then stripped) is 114K.

1,14к она должна макс. занимать, а на ассемблере ещё раз в 10-20 меньше, ) т.ч. хвастаться нечем.


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"Oxidative Stress in a Rat Model of Chronic Gliosis" by Kristyn Bates, Ralph Martins et al.
Alzheimer's disease is a progressive neurodegenerative disorder characterised by abnormal extracellular deposition of a 4 kDa peptide termed beta-amyloid, neuronal loss, oxidative stress and chronic astrocytosis and microgliosis, but how the latter two features contribute to the progression of the disease is poorly understood. We have previously demonstrated in a novel in vivo transplantation model that chronic astro- and microgliosis resulted in molecular pathology similar to that observed in the Alzheimer's disease brain. We now report that these heterotopic, gliotic transplants exhibit prolonged oxidative stress, characterised by lipid peroxidation and protein carbonyl formation. Furthermore, we demonstrate that dietary additives can elevate endogenous anti-oxidant defences and reduce oxidative stress without attenuating astro- and microgliosis. We also show that administration of ibuprofen through the drinking water results in a similar reduction in oxidative stress but with no observable effect on glial reactivity. The present study lends support to the notion that dietary anti-oxidants and non-steroidal anti-inflammatory drugs may be potential preventative agents against some of the pathological processes associated with neurodegenerative disease.


text:
Consolidation is coming for the self-driving vehicle industry. Will only three firms reach the finish line?
In 2017, operators ride inside one of Uber's self-driving SUVs along Penn Avenue in the Strip District. (Stephanie Strasburg/Pittsburgh Post-Gazette)
Argo AI's big money partnerships with Ford and Volkswagen are only part of a complicated and growing road map of relationships
Courtney Linder
clinder@post-gazette.com
In 2016, nobody knew what Argo AI was.
It was a scrappy artificial intelligence startup with lofty goals and industry veterans ready to jump ship from other self-driving firms, eager to try a new approach of making robot cars.
Reinventing the wheel was not exactly on CEO Bryan Salesky's agenda.
The heart of Argo's business model was — and is — quintessentially anti-Silicon Valley: Snuggle up with industry titans that have deep pockets and make them investor-partners. To this day, the startup has funding from only two firms, keeping the rest of the equity for employees.
"We always thought that would be a compelling business model because it's a capital-intensive thing," said Mr. Salesky, a Pittsburgh native. "That's not foreign to a large manufacturing company. They need the help because those companies don't typically build software well."
Truth is, no company trying to crack the autonomous vehicle code is moving anywhere quickly without help. A complicated web of partnerships and acquisitions has formed, helping firms create economies of scale to become more efficient.
Even companies working together to leverage one another's expertise haven't dropped their guard. Mr. Salesky believes that when the winning self-driving companies do emerge, he'll be able to count them on one hand.
In evidence of the growing number of partnerships in the industry, this 2017 photo shows a group of Argo AI and Ford officials getting together. From left, Peter Rander, Argo AI COO; Ken Washington, Ford vice president of research and advanced engineering; Mark Fields, former Ford president and CEO; Bryan Salesky, Argo AI CEO; Raj Nair, former Ford executive vice president, product development, and chief technical officer; and Laura Merling, former Ford Smart Mobility LLC vice president of autonomous vehicle solutions. (Image courtesy of Argo AI)
But it's still worth partnering up. Companies that work together will find success more quickly than larger firms keeping to themselves, if the parties can put ego aside, he said.
Three years after its founding, Argo has wooed two of the industry's major auto manufacturers, Ford and Volkswagen, into investing billions of dollars into the business, which hit a $7 billion valuation in mid-July.
"Automobile companies realize that if they don't partner, they'll be left behind," said Timothy Derdenger, associate professor of marketing and strategy at Carnegie Mellon University's Tepper School of Business in Oakland.
"They don't have the technical capabilities to really go alone at it, or if they did have the technical capabilities, they're so bogged down by the slow pace of their industry."
An Aurora Innovation autonomous vehicle cruises over the Fort Pitt Bridge. (Image courtesy of Aurora Innovation)
Sprite. Unito. Wolfe. Angus. Empire. Not exactly household names.
These early car companies are just some of the thousands that existed more than a century ago, when the horseless carriage started thrilling the world.
Companies like Ford, General Motors and Chrysler emerged as the winners — and they're now competing in the fledgling self-driving market.
In a 2016 photo, one of Uber's autonomous Volvos makes a turn onto Seventh Avenue from Grant Street during the morning rush. (Darrell Sapp/Post-Gazette)
Many small auto manufacturers that fizzled out began in the late 1890s or early 1900s. That graveyard isn't particularly unusual.
Most industries face a "consolidation curve," according to a 2002 analysis in the Harvard Business Review, a business journal associated with the Cambridge, Mass.-based university. That contraction, which consists of four phases, is happening more quickly than in the past.
"Today, we predict, an industry will take on average 25 years to progress through all four stages; in the past it took somewhat longer, and in the future we expect it to be even quicker," the authors wrote. "But, our research suggests, every company in every industry will go through these four stages — or disappear."
Differentiation is partly what leads some companies to success, Mr. Derdenger said.
"You see this in every industry … competition plays out and then you start to see the cream of the crop rise to the top and everyone else goes away," he said.
This is similar to the auto industry at the turn of the century, Mr. Derdenger pointed out.
"You saw a bunch of entry, competition and the best rose to the top. And the reason Ford rose to the top is Henry Ford and his knowledge of the assembly line to reduce costs and scale," he said.
The Autonomous melting pot
In 2017, an Aptiv vehicle with autonomous technology in Las Vegas, Nevada. (Photo by John F. Martin for Aptiv)
Sterling Anderson, Chris Urmson and Drew Bagnell are the three founders of Aurora Innovation, a Lawrenceville-based company that creates software for self-driving cars. (Image courtesy of Aurora Innovation)
Some competitors in the autonomous vehicles race raise money to fuel their development by seeking rounds of venture capital. It's a common system across industries that allows founders to trade equity in their companies for cash.
In February, Aurora Innovation, based in Lawrenceville, took $530 million in Series B venture capital funding from Seattle-based Amazon and investment company Sequoia Partners, based in Menlo Park, Calif.
Meanwhile, Aptiv, a self-driving firm based in O'Hara, has been working with ride-hailing service, Lyft, since May 2018, offering riders trips in the company's autonomous vehicles in Las Vegas as part of a bid to collect data on miles driven.
Lyft itself is not a one-partner kind of company. It's also cozy with General Motors and Waymo, the self-driving outfit spun out of Google's parent company, Alphabet.
Mapping the self-driving web Every week, it seems there's a new partnership, acquisition or investment in companies developing self-driving vehicles. From artificial intelligence startups to automobile manufacturers, hardware and software companies, to even rental car agencies, the web is spinning tighter and tighter. We mapped the relationships between these companies for you to better understand the autonomous vehicles race. Click or tap on the chart below to begin exploring company relationships.
Despite all of the partnerships, most entities have retained their own unique brand. Argo struggled with that early on.
In 2017, after Ford invested $1 billion into the Pittsburgh startup, it turned heads. What is Argo AI? Is it a subsidiary of the Michigan automaker?
"Just because we gave them some equity in the company doesn't mean that they control our every existence," Mr. Salesky said. "The whole point was to partner with the [auto companies] in such a way that we had access to their manufacturing capability and scale and the ability to take us into lots of different markets."
Pete Rander, president of Argo AI, emphasizes the company is not some sort of department at Ford. Argo is an independent company that will eventually go public, he told the Post-Gazette last September.
With the infusion of another $2.6 billion from Volkswagen last month, Argo's profile became clearer. It is its own firm, with its own vision, its own employees, its own patents. It just happens to reel in big customers.
"You can't build stuff like this just within the four walls of an [original equipment manufacturer]. It takes a different culture, a different type of company that can move fast," Mr. Salesky said.
Foes becoming friends
In a March 2019 press conference announcing that self-driving companies were working with the city of Pittsburgh on testing guidelines, several industry representatives stood by their technology. From left, Pete Rander, president of Argo AI; Khobi Brooklyn, vice president of communications of Aurora; Raj Rajkumar, co-director of the General Motors-Carnegie Mellon Vehicular Information Technology Collaborative Research Lab; Junqing Wei, vice president of engineering of Aptiv; and Eric Meyhofer, head of Advanced Technologies Group of Uber. (Lake Fong/Post-Gazette)
It usually takes millions of dollars per year to develop and test self-driving cars, so spreading the costs among partner companies makes sense.
Uber spent $97 million on autonomous vehicles research at its Advanced Technologies Group in the Strip District during the second quarter alone, according to a filing this year with the Securities and Exchange Commission. That's down from $117 million during the same period in 2018.
Those figures also include expenses related to other programs that Uber defines as "next-generation technologies."
Aurora Innovation — after having severed ties with Volkswagen just before the German automaker jumped ship for Argo — partnered with Fiat Chrysler, a U.K.-based automaker, to deploy vehicles with autonomous capabilities.
Fiat Chrysler will manufacture the autonomous-enabled cars, with Aurora building out the brains of the operation. All the more reason to partner — it allows companies to lean on others' expertise rather than starting from scratch.
That's always been one of Argo AI's strategies, Mr. Salesky said.
"We think that those who are going to have success … are tooling around with technology and creating a platform," he said. "Because why reinvent the wheel on something that's so hard to begin with?"
Jim Hackett, president and CEO of Ford, said in the company's second-quarter earnings call last month that he's pleased with Volkwagen's decision to invest in Argo AI.
Ford's investment in what it calls its "mobility segment" has increased from $181 million in the second quarter of 2018 to $264 million during the same period this year, according to company filings. This is mostly cash for Argo AI operations — the $1 billion investment in 2017 is spread out over the course of five years.
Ford and Volkswagen will pool valuable data, expertise and, naturally, development costs.
"Ford and VW, of course, will remain vigorous competitors … with each of us designing and delivering unique experiences for our customers," he said.
Four stages of consolidation
Earlier this year, self-driving firm Aurora Innovation announced a $530 million investment. (Image courtesy of Aurora Innovation)
The consolidation curve consists of four stages.
First is the "opening stage," which usually begins with a few private startups or a monopoly created by deregulation, like utilities.
Soon, competitors will begin to crop up, so early entrants — like Waymo in Mountain View, Calif. — look for ways to create barriers for entry. Technological advancements in the form of trade secrets and patents are essential, as well as spending to create scale.
Mr. Derdenger doesn't think the self-driving industry is on the consolidation chart yet. These companies may just be entering phase one. Mr. Salesky thinks some companies could be in the first phase.
The other stages are "scale"; "focus," which is when the playing field starts to tighten and remaining firms really start to focus on profitability; and "balance and alliance," which is where the top three or so companies claim as much as 70% to 90% of the market.
The consolidation curve There's been research on how new industries form and then eventually consolidate into key players. Here's the life cycle as determined by a study of more than 1,300 large mergers.
Sources: Harvard Business Review, 2002 article by Graeme K. Deans, Fritz Kroeger and Stefan Zeisel of A.T. Kearney and authors of book, "Winning the Merger Endgame: A Playbook for Profiting from Industry Consolidation." | Post-Gazette
A 'complex business'
An aerial view of Hazelwood Green along the Monongahela River with the city skyline in the background in 2018. In the foreground is the Uber test track. (Darrell Sapp/Post-Gazette)
Companies don't leave the fourth stage of consolidation. They stay there and try to maintain their position at the top. Industries like tobacco and soft drink beverage companies have famously made it to this point.
Mr. Derdenger said when smaller tech startups start leaving the industry, licensing their intellectual property to larger firms, it's a signal the winning companies may be getting close to stage four.
In the self-driving industry, it may also mean they are approaching level four of autonomy, a standard wherein cars no longer need humans to operate the vehicle.
Mr. Salesky ultimately believes that there's room for only three firms to win. "I want the companies who are doing it right to be successful, even if they're competitive with us."
Courtney Linder: clinder@post-gazette.com or 412-263-1707. Twitter: @linderrama.

redpajama_set_name: RedPajamaCommonCrawl


text:
Q: Sum of angles related to a triangle I have got a multiple choice question, which is below:

and the question is what is value of x+y
below are the choices:

*

*180

*185

*190

*195

*200

I have tried but not understand how to solve this. Please help me to solve this problem.

A: $(180^{\circ}-y)+(180^{\circ}-125^{\circ})+ x=180^{\circ}$. You can tell $y-x=55^{\circ}$ but can not determine $x+y$ from just what's given.

A: You cannot determine $x+y$ because, if you have a solution, it suffices that you take CB slightly more vertical, say, and this will result in an increase of both $x$ and $y$!

A: $$ (180^0 -y) + x = 125^0$$
 $$ y-x = 55^0$$
That is all. The given problem cannot be solved as it is about $(x+y)$

A: The answer is 5.
Indeed, from the knowledge of $x-y$ and $x+y$, the possible angles $A,B,C$ are

*

*$ 55.0 , 62.5 , 62.5 $

*$ 55.0 , 60.0 , 65.0 $

*$ 55.0 , 57.5 , 67.5 $

*$ 55.0 , 55.0 , 70.0 $

*$ 55.0 , 52.5 , 72.5 $
and only the last proposal is such that $B<A$ ($C$ closer to $A$ than to $B$).

redpajama_set_name: RedPajamaStackExchange


Freshness and quality are important to Martin's Famous Potato Rolls and Bread. The company uses high protein wheat flour (and for whole wheat products, 100 percent stone-ground whole wheat), nonfat milk, potatoes, pure cane sugar, yeast, sunflower oil, and real butter in their bakery products. Their products contain no artificial colors or artificial sweeteners, and they source all non-Genetically Modified Organism (non-GMO) ingredients.
"Quality is crucial to our brand, and the efficiency of our operations is essential, especially since Martin's bakery products are only on the stores shelves for 3-4 days, which is a significantly shorter amount of time than our competitors' products," Martin said.
The new production space is designed with the future in mind so that production capacity in this space can be increased as the market dictates. The newest line will encompass state-of-the-art baking technology that includes production efficiency, automation, and verification processes that promote the highest quality in food safety standards.
The Martin's Potato Roll and Bread bakery in Valdosta has been producing Martin's products since 2008. The design, build, and installation of this new production line will be completed by February 2019.
Martin's Famous Pastry Shoppe, Inc.®, is an all-American family owned and operated consumer goods company headquartered in Chambersburg, PA, with a second location in Valdosta, GA, focused on baking high-quality bread and roll products using high-quality ingredients. They are rigorously dedicated to extraordinary taste, quality, and customer service that proudly represents their legacy of cherished eating experiences and truly sets them apart from their competitors. Since the 1950s, the business has expanded from a home garage business into two commercial baking plants and continues to grow and flourish in areas of established distribution. For more information, visit www.potatorolls.com.


We love QuickBooks Online. The leading cloud accounting software gives us flexibility and deep access to the numbers of the people we work with. Becoming a QuickBooks Gold Partner is a great milestone on our on-going journey and we're really proud to be accredited by the global leader in cloud accounting software!
What does QuickBooks mean for you?
One of the reasons we use QuickBooks – and encourage you to use it as well – is that it makes it easier for you to work with us collaboratively.
When you put your accounting on QuickBooks, we both win because we have access to the numbers from anywhere in the world. Not only this, but the techno guys at QuickBooks make sure the software is always up to date.
There are also hundreds of nifty add-ons available – from credit control to inventory tracking to website building – all of which integrate with QuickBooks Online and bring a variety of different new functions and automated processes to your finance systems.
Why does it matter that we're a QuickBooks partner?
If you are using old or outdated software (perhaps even Excel, or pen and paper) to manage your accounts and financial data, think about switching to QuickBooks.
As a QuickBooks Gold Partner, we have the processes in place, and the hands-on experience needed, to help make the switch from your old software a simple matter. Read more (link to consulting).


text:
David Lazzaroni, né le  à Échirolles, Isère, est un sauteur à ski français.

Biographie

Carrière sportive
Lazzaroni commence à s'entraîner dès son enfance sur de petits tremplins et rejoint le club de l'US Autrans. En 1995, il fait son premier saut sur un tremplin K-90, à Hinterzarten (Allemagne). À l'âge de 16 ans, il arrête pendant quelque temps de s'entraîner à cause d'un manque de motivation. Cependant, quand il voit à la télévision les mauvais résultats des sauteurs à ski français au sein des JO 2002 à Salt Lake City, il décide de recommencer l'entraînement, pour qu'il fasse mieux que ses coéquipiers. Lors de sa première apparition au sein de la Coupe du monde, sur le tremplin de vol à ski à Planica (Slovénie), en mars 2002, il est le meilleur sauteur français dans l'épreuve par équipes, avant de faire ses débuts individuels à Oslo. Depuis, il a atteint plusieurs résultats dans les top 30, parmi eux la  à Harrachov, en décembre 2005 pour marquer ses premiers points (top 30). Entre-temps ses meilleurs résultats sont enregistrés dans la Coupe continentale, notamment avec une quatrième place à Rovaniemi en
décembre 2004.

En mars 2007, il signe son premier top dix dans la Coupe du monde avec une dixième place à Oslo. En mars 2008, il obtient son meilleur résultat individuel avec une sixième place à Harrachov. Avec également une septième place à Oslo, il finit l'hiver 2007-2008 au  rang du classement général, son dernier qu'il enregistre dans cette compétition. Dans les Championnats du monde, il compte trois sélections entre 2005 et 2009, se classant au mieux individuellement  au petit tremplin à Oberstdorf en 2005.

À la fin de la saison 2009-2010, où il participe aux Jeux olympiques de Vancouver ( et  en individuel) il décide à seulement 25 ans de prendre sa retraite sportive en raison de problèmes dorsaux et à la suite du départ de l'entraîneur finlandais de l'équipe de France de saut à ski Pekka Niemelä.

Vie personnelle
Sur le site de la FIS, il est indiqué que David Lazzaroni est maître nageur, il s'agit d'un job d'été qu'il a eu. David Lazzaroni a un contrat avec l'armée de l'air française.
Il est le fils d'Éric Lazzaroni, lui même sauteur a ski, devenu entraîneur de l'équipe de France de combiné nordique.

Palmarès

Jeux olympiques d'hiver

Championnats du monde

Championnats du monde de vol à ski

Coupe du monde
 Meilleur classement général :  en 2008.
 Meilleur résultat individuel : .

Classements généraux annuels

Références

Liens externes

Naissance en février 1985
Naissance à Échirolles
Sauteur à ski français
Sauteur à ski aux Jeux olympiques d'hiver de 2010

redpajama_set_name: RedPajamaWikipedia


Infectious bronchitis (IB) is a widespread acute, highly contagious, upper-respiratory tract infection caused by the infectious bronchitis virus (IBV), a coronavirus. The disease was first reported in 1931 and since then has become a threat to chickens across all industries worldwide. It primarily affects the bird's respiratory tract, but can also cause damage to the kidneys and reproductive system. There are several types of vaccines available, however the emergence of multiple strands of the virus have made control difficult.
Outbreaks of IB frequently occur, even in vaccinated flocks. IB spreads rapidly among chickens in a flock, resulting in all birds eventually becoming infected, in a short period of time. Susceptible birds placed with infected chickens usually develop clinical signs of illness within 24–48 hours. The severity of the infection varies depending on the bird's immune status, age, virus strain, and whether secondary infections are involved.
What are the symptoms of infectious bronchitis?
What are the potential complications of infectious bronchitis?
Secondary bacterial infections: IBV damages the chicken's respiratory epithelium, often predisposing young chicks to secondary infections with pathogenic bacteria, such as Escherichia coli and Mycoplasma spp. Two of the most common secondary manifestations resulting from E. coli infection in chickens, following IBV infections are airsacculitis and systemic colibacillosis.
Kidney damage: Some strains of IBV are nephrogenic, meaning that after replicating in the bird's trachea (and causing respiratory disease), the virus will then spread to the kidneys (causing nephritis—or inflammation of the kidneys). Nephritis results in damage to the kidneys which often leads to renal failure and increases the risk of birds developing gout. Typical signs of renal failure include: increased water intake, rapid weight loss, and diarrhea in affected birds.
Signs of IB appear similar to many other respiratory diseases. One of the most confused include IB and Infectious Corzya.
Both Infectious Bronchitis (IB) and Infectious Coryza (IC) cause acute respiratory disease in chickens, however IB is caused by a coronavirus, and IC is caused by bacteria. The best way to achieve a confirmed diagnosis of IB is through submitting a sample (tracheal swabs or tracheal tissue obtained from the infected or dead chicken) to a veterinary diagnostic laboratory for virus isolation. Otherwise, IB and IC can often be differentiated by the presence of facial swelling. Facial swelling occurs frequently in chickens with IC, but only on rare occasions in chickens with IB.
IBV spreads rapidly among chickens in a flock and is transmitted through direct and indirect contact with contaminated feed, water, equipment, environment, or infected birds. The virus is shed through nasal discharge and feces of infected or vaccinated birds. Carrier chickens and recovered chickens can also spread the disease, as birds may shed the virus for up to 4 weeks after recovery. IBV can survive outdoors in the environment for up to 12 days in the spring and up to 56 days in the winter (it survives longer during cooler temperatures). However, it is rapidly killed by common disinfectants.
Combining birds that were vaccinated against IBV with unvaccinated chickens.


For those of you watching the All Blacks take on Ireland at Eden Park tonight you'll notice that the front three for New Zeland all have new boots on their feet. Tony Woodcock, Andrew Hore and Owen Franks were spotted in training this week wearing the new adidas adipower Kakari boots. They are also expected to be worn by Ireland's Paul O'Connell.
They are the latest boots for those in the pack, that replace those previously known as the adidas Flanker, the name change makes sense as players in all positions of the front eight can wear them, not just loosies.
After the players gave feedback to adidas, the Kakari are 10% lighter than the Flanker, the upper is a new Bravo synthetic leather which has the feel of a soft K-leather but is far stronger and is desingned to withstand deformation and stretching. There is also a 5mm heel wedge for reduced stress on the lower body. They are also micoach compatible, just don't tell your coach!
New boy Brodie Retallick, who'll get his first cap for the All Blacks in the Ireland game after having impressed at Lock for the Chiefs in Super Rugby will be wearing the exact same boot, but in the alternative white colourway, that we saw him wearing at training this week too.


MBI has developed a proprietary Soft Hydrophobic Acrylic material that incorporates the most desirable UV blocking properties for their yellow and clear PresiSAL Intraocular lenses. Utilizing this base material, a unique family of intraocular lenses has been developed and CE Mark approved.
There is no need changing your implantation technique. MBI offers an easy, controlled implantation with highest quality standard. All MBI intraocular lenses are designed and manufactured in USA. All PreciSAL models demonstrate extremely high stability and safety in the capsular bag.
PreciSAL intraocular lenses are currently available in Diopter powers from 0.0 D to 30.0 D for monofocal and 10.0 D to 30.0 D with added +1.0 D to +6.0 D cylinder for toric IOLs.


text:
Mostrando entradas con la etiqueta Art Rock. Mostrar todas las entradas
Lemon Kittens – The Big Dentist (LP, 1982, Illuminated Records – JAMS 131 ) FLAC
Artist Biography by Andy Kellman
With no "proper" musical skills upon their formation in Surrey, England, the Lemon Kittens epitomized the "anything goes" spirit of late-'70s post-punk in the U.K. Karl Blake, who cut his teeth in numerous outfits prior to the Lemon Kittens, started the band with Gary Thatcher and a revolving cast of others (which at one point included future Alternative TV leader Mark Perry), but at the time of the release of their first EP in 1979, the seven-song Spoonfed + Writhing 7", the group's lineup featured Blake, Thatcher, N. Mercer, Mylmus, and Danielle Dax. The group was whittled down to a duo of Blake and Dax by February of 1980; the other three members had fled, making for the group's 16th different lineup change since initialization in April 1978. Blake and Dax then decided to operate primarily as a duo, with help coming from whoever whenever they needed the assistance to perform. Later in 1980, Blake and Dax released We Buy a Hammer for Daddy on the United Dairies label (their labelmates included fellow oddballs and noise-mongers Whitehouse and Nurse With Wound), an album that featured the duo swapping a wide variety of instruments. The Cake Beast EP came out in February of 1981; Dax left after its release to begin a successful solo career, which Blake took part in sporadically throughout the '90s. In late 1982, the Illuminated LP Those That Bite the Hand That Feeds Them Must Sooner or Later Meet...the Big Dentist (best referred to as The Big Dentist) became the group's second full-length. Blake rounded up a new group of cronies, laid the Lemon Kittens to rest, and began the Shock Headed Peters.
Lemon Kittens – The Big Dentist
Label:Illuminated Records – JAMS 131
Format:Vinyl, LP, Album
Country:UK
Genre:Electronic, Rock
Style:Art Rock, Experimental
A1 They Are Both Dirty 11:19
A2 The Hospital Hurts The Girl 4:30
A3 Mylmus 4:09
B1 No Night Not Shared 4:55
B2 Oath 4:08
B3 The Log And The Pin 4:00
B4 Nudies 3:17
B5 An Untimely End 2:11
BONUS!!
Lemon Kittens, London, ICA, December 27, 1980
Part of a new wave festival "Rock Week Plus" at the ICA, London
only 3 tracks
Lemon Kittens:
Karl Blake
Danielle Dax
01. Death By Leeches
02. PBS
Publicado por savecueandlog en 9:27
Etiquetas: Art Rock, Danielle Dax, experimental, Karl Blake, LEMON KITTENS


TORONTO – Canada has been named as a potential target by terrorists, but the vast majority of potential targets are managed by the private sector, experts told a Conference Board event Wednesday.
In response, Canada's chemical, biological, radiological and nuclear research and technology initiative is broadening its investment in science and technology, and focusing on collaboration between government, academia and the private sector.
"We have to start predicting and delivering technologies in advance of an event," said Camille Boulet, director of the CBRN Research and Technology Initiative (CRTI) with Defence Research and Development Canada, during a conference on Business & Technology Opportunities in National Security and Public Safety.
The CRTI is a partnership between federal departments and agencies, and its success is largely dependent upon relationships with first responders, the science and technology community and the international security community.
It has broadened its original mandate to include the Public Security Technical Program (PSTP), with a goal to provide governments with solutions before a crisis actually hits. Launched in July 2003, the PSTP is a joint U.S.-Canada program aimed at enhancing critical infrastructure protection and border security through the collaborative delivery of science and technology solutions. In the future, the program could include Australia and the U.K.
So far, there are 17 projects approved or pending between the U.S. and Canada, and Boulet said international partners are necessary to the future expansion of its collaborative model. The CRTI is also cooperating with the U.K. Nuclear Threat Reduction organization and the Health Protection Agency's Emergency Response Division.
The PSTP's mission areas include chemical, biological, radiological, nuclear and explosive threats, critical infrastructure protection, disruption and interdiction and systems integration standards and analysis.
Targets could include people, critical infrastructure, the food supply, the water supply, agro-terrorism plants and agro-terrorism animals. Even Mother Nature herself can be a terrorist entity, said Boulet. Attacks might be deliberate, but they could also be natural, accidental or caused by neglect.
So far the CRTI has 120 projects on the go. "Technology acceleration" projects, for example, include a handheld real-time biological detector and MEMS sensor for bio-agent detection and identification. "Research and technology" projects include therapeutic antibodies for the Ebola virus, 2D molecular imprinting techniques for sensors and rapid assessment of radioactive contamination.
After 9/11, Canada invested $170 million over five years in the areas of science and technology research, providing a single program focused on national security for government, academia and the private sector.
The 2006 budget includes $15.5 million, but the CRTI is requesting an additional $135 million. Despite government funding, the CRTI relies on co-investment through contributions by project partners. Government isn't always great at commercializing technology, said Boulet, and the academic sector doesn't always focus research on commercial solutions, so private-public partnerships play a key role in getting technology initiatives off the ground.
There's a need for industry to work with government on national security, said Gene McLean, vice-president and chief security officer with Telus Communications Inc.
Telus, for example, is working with the provinces to develop operational emergency response centres and alert notification systems, he said. Telecom is a cornerstone to Canadian critical infrastructure, he added, and loss due to a cyber or physical event could have a significant impact on other sectors.
"Interdependency is huge, there's no doubt about that," he said. There are a number of collaborative efforts between government and the telecom industry, such as the Canadian Telecommunications Cyber Protection Working Group, the Canadian Telecommunications Emergency Preparedness Association and the U.S. Network Security Information Exchange (a similar organization is being created in Canada).
The Business & Technology Opportunities in National Security and Public Safety conference focused on how governments can collaborate with the private sector to protect Canada's national security.


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Mount Bishop (British Columbia)
Mount Bishop (British Columbia) – Climbing, Hiking & Mountaineering
Photo credit: PAFC Woody
Mount Bishop (British Columbia) Climbing Notes
Please submit any useful information about climbing Mount Bishop (British Columbia) that may be useful to other climbers. Consider things such as access and accommodation at the base of Mount Bishop (British Columbia), as well as the logistics of climbing to the summit.
Select Mount Bishop (British Columbia) Location Map Detail:
Use this relief map to navigate to mountain peaks in the area of Mount Bishop (British Columbia).
10 other mountain peaks closest to Mount Bishop (British Columbia):
1. Mount Elsay (1419 m) 2.7 km
2. Mount Seymour (1449 m) 4.3 km
3. Mount Fromme (1185 m) 10.8 km
4. Goat Mountain (Vancouver, British Columbia) (1401 m) 11.4 km
5. Eagle Mountain (British Columbia) (1050 m) 11.5 km
6. Crown Mountain (North Vancouver, British Columbia) (1504 m) 12.2 km
7. Grouse Mountain (1231 m) 12.5 km
8. Coquitlam Mountain (1583 m) 16.5 km
9. The Forefinger (mountain) (1741 m) 16.8 km
10. Burnaby Mountain (370 m) 16.9 km


text:
Q: TypeScript mutating prop Why is born_date being mutated? I'm cloning it to date before making changes to it, is there something I'm missing?
export default class Gigasecond {
  born_date: Date;

  constructor(date: Date) {
    this.born_date = date;
  }

  date(): Date {
    let date = this.born_date;
    let date_plus_giga = date.getSeconds() + 1000000000;
    date.setSeconds(date_plus_giga);
    return date;
  }
}

A: let date = this.born_date; is not achieving your desired behavior of cloning the date. It's copying a reference to the date object, and then the call to setSeconds later mutates the object (which is both referenced by the member born_date and the local variable date).
To clone the date object, you can do this: let date = new Date(this.born_date.valueOf());.


text:
Hjalmar Selander ( près de Göteborg -  à Stockholm) est un acteur, régisseur et directeur de théâtre suédois.

Biographie
Selander fut actif à Göteborg de 1877 à 1879, dans plusieurs compagnies de théâtre itinérantes de 1879 à 1888 et au Théâtre suédois à Stockholm en 1888-1889.
Il se maria en 1887 à Concordia Selander, qui dirigea pendant plusieurs années la Selander Company, qu'elle avait créée en 1889.

Filmographie
 1917 : La Fille de la tourbière (Tösen från stormyrtorpet), de Victor Sjöström
 1919 : Le Trésor d'Arne (Herr Arnes pengar), de Mauritz Stiller
 1920 : Familjens traditioner (Familjens traditioner), de Rune Carlsten
 1920 : Mästerman
 1928 : Gustaf Wasa del I
 1928 : Gustaf Wasa del II

Liens externes

  Hjalmar Selander dans la Svenskt porträttgalleri sur le site runeberg.org

Acteur suédois
Naissance en juillet 1859
Naissance dans le comté de Västra Götaland
Décès en août 1928
Décès à 69 ans


text:
Writing for Ghosts
The Online Abode of Writer Robert Crisp
Why Writing For Ghosts?
Notice of Copyright Protection
Forthcoming Work
Tag fiction
Jenny and the Gorgon (freewriting)
October 26, 2018 Robert Crisp	Leave a comment
Writing something weird is better than writing nothing at all, eh?
Do you remember the time with scaled that mountain and you fell and busted your back? Jesus, you were laid up for six months in the hospital, and you did all that physical therapy. What was the therapist's name? You slept with him, which is all kinds of fucked up, but I try not to judge. I try and fail. Ha ha.
Darren, that was his name. I'm not saying he wasn't attractive, but you getting in bed with him made as much sense as a lizard in a blender, which–I don't mind telling you–doesn't make a hell of a lot of sense at all. That's what my daddy used to say, before he turned to stone. Speaking of weird-ass things, how many people you know that just, like, suddenly turn to stone? It threw me for a bit, I'll tell you. And when other people started turning to stone, I figured it was some kind of chemical attack, some country that had cooked up this lethal gas that made people into statues. But it turned out a gorgon had gotten loose, which would mean that she had been held somewhere to begin with, for something like a thousand years, and then she was set free and she was like, "Fuck, it's been a long time, I'm going to set these eyes on the first miserable bastard that comes along," and bam, just like that, Daddy was stone. He had just woken up, had his first cup of coffee, and opened the front door. Little did he know a gorgon was slithering down the street.
That's the kind of fucked-up world we live in, Jenny. Trump in the White House, gorgons roaming the streets, ol' Ms. Shookapoo coming down with the gout. Did you know women could get gout? I thought it was a man thing. Hell, I hope I don't get it.
No, Jenny, it wasn't Medusa! Lord God! It was another one. Maybe they cut her head off and put it in a bag, and they'll keep it around in case something big-ass monster shows up, like they did with Medusa, who's apparently the only gorgon you think existed. Crack a book open, Jenny, and get off that damn YouTube!
I swear, you and the YouTube! Its like you think it's magic or something. Maybe it is magic for you and you're under its damn spell, so I think it would be best if I just smashed the daylights out of the computer and run over your phone in my truck. Then what, Jenny? Then you'd be more worried about the damn gorgon, is what.
Ben the Would-Be Cannibal (story snippet)
October 7, 2018 Robert Crisp	Leave a comment
I came across this story snippet as I was going through some old writing, and I was struck by how often cannibalism comes up as a theme in my work. Also, for every completed story, I have perhaps fifty or so partial stories. So it goes.
No picture for this one. I'm not terribly keen on Googling "cannibalism."
"I'm supposed to care about something, you know," Ben said as he chewed on a face.
"What if I'm a sociopath?"
"Well," Donovan observed, "you're eating a human head. And just because you're
supposed to do something doesn't mean you should. Shit, I'm supposed to go
to church, but I don't. Also, I'm sitting here as you demonstrate you're a cannibal, so
what does that say about me? I'm supposed to stop you, right? Or at least protest in
some way?"
Ben sighed. "I'm not really a cannibal. This is processed."
"Doesn't matter. You're eating a processed human, which they say tastes like the real deal."
"I guess."
"You haven't eaten a real person, right?"
Ben sighed again. "No." He could have, of course. There was nothing stopping him
from exploring the black market and picking a body. It would be dressed-out and
ready to cook. Instead, he was gnawing on human-flavored gelatin face. What
respectable cannibal would eat a face, anyway? Could you even cook a head and have
the features stay in place? Maybe if you closed the eyelids and simmered it in broth,
Ben reasoned. The facsimile face he was dining on had gooey, sweet-flavored eyeballs.
He imagined the real deal was a bit tougher and more salty.
"So why are you worried you're a sociopath?" Donovan asked. "I mean, the current
activity notwithstanding?"
"Because like I said, I don't care about anything. Not school, not girls, or cars.
Nothing, man. It's a scary feeling."
"Which means you're not a sociopath. Do you think a real sociopath pauses to
reflect on his lack of empathy?"
"Maybe. Like, early in their sociopathy."
"Have you ever tortured or killed animals?"
"That doesn't mean anything, Donovan. The mutilation of animals is only one
indicator in a wide variety of cues that might signal someone's a sociopath."
"Well, for someone who doesn't like school, you don't seem to have a problem
learning. At least about sociopaths."
Ben shrugged and ate.
Donovan studied the beheaded false corpse before him. Eventually, Ben would have to
remove its clothes, and Donovan didn't want to be around for that. Ben had
ordered a male corpse, which Donovan guess was better than a female corpse, but he
really wasn't sure why…
The Pattern (short fiction)
October 5, 2018 October 5, 2018 Robert Crisp	Leave a comment
In the spirit of Joyce Carol Oates. Please pardon any typos I may have missed.
The Pattern
If she looked closely, she could see a pattern, and she could see herself in the pattern. This didn't happen every day, of course–she had to be in the right frame of mind and receptive to receiving the pattern and her place in it. Over the years since the accident, she estimated that she'd detected the pattern about fifty times. Of that fifty, she'd located herself in the pattern about twenty times.
She couldn't talk about the pattern with anyone, not her husband, not her sisters, and certainly not her friends. But they weren't really friends, were they? And as much as she loved her sisters and her husband, that weren't of ultimate consequence. The accident had proven that she could live without them. She could live without anyone, or so the pattern indicated, and she believed the pattern over all things.
After the accident, she lay in a coma for three months, and that's when the pattern had come to her. When she woke to her broken body, her torn and disfigured face, the pattern was burned into her mind. She remember the fiery way it came, like the tongues of flames that appeared above the apostles head on Pentecost, She'd known she was on the brink of death; that feeling permeated everything. In the coma, she had a series of dreams, all of which were lit by the fire of the pattern. It flickered over walls, highlighted the ground, filled the sky. Sometimes she dreamed she was a young girl, and other times she was a old woman. No matter the dream, no matter the non-sequiturs her mind strung together, the fire followed, and she felt peaceful.
Nearly a year of physical rehabilitation followed her waking, and she bore it with uncharacteristic stoicism. Her husband said she was remarkably brave, and she just nodded. He was afraid of her, afraid of her new-found strength and determination. Her doctors were skeptical that she would walk again, but she was walking after six months. She underwent two surgeries on her face but stopped short of cosmetic repair. The scars formed their own pattern, and she liked them. Her husband urged her to get the cosmetic surgery, but she wouldn't be swayed.
When she was cleared to leave the rehab unit, she found her house stifling. It was no longer her home, she realized, and she convinced her husband to sell it. In the home's place, they settled into a small apartment in a neighborhood that made the husband uncomfortable, but he found that he couldn't tell his wife no. She had been returned to him, more or less whole, and every day was a gift, or so he told himself She wanted to move, and so they moved. He would grow accustomed to the neighborhood with its loud music and questionable young men who stood on the corner, laughing and smoking and hitting each other. He had been a young man once, but he had never acted like that.
She went for long walks, even though it was painful. She walked with a limp and would for the rest of her life, or so the doctors said. That was all right, she decided. Her new neighbors stared openly at her, disturbing by her ruined face. That was all right, too.
She couldn't have explained the pattern to anyone, even if she felt they could be trusted. The pattern defied description, and it could be apprehended by her alone. It made her sad sometimes that she couldn't locate herself always in the pattern, but ultimately she decided that was the nature of life and, indeed, the nature of the universe. The universe didn't have to include you in its plans, but it was wonderful when it did.
As much as she could determine from the pattern, she had only to follow it when prompted. The first indication had been to leave her house, which she had done. The next part had been to walk through her neighborhood as much as she could, mentally mapping the terrain, and she did that.
She hadn't worked since the accident. She found she hated her job and work in general, and she was relieved when she discovered her company had terminated her. What a horrible thing, work, she realized. Her husband was an investment banker and made more than enough money to support them both, but he wondered if she wanted to perhaps get a part-time job or maybe volunteer. She shook her head no. It's not that there wasn't time for such things, for there was, even with the promise of the pattern. But she had no desire to do anything unrelated to the pattern.
Her husband was more patient than most men, and he felt overwhelming guilt whenever he allowed himself to wonder What's wrong with her? She's healed physically, but it's like the rest of her is just…elsewhere. She would have agreed with that sentiment, had the husband shared it. She was certainly elsewhere in her mind, her spirit. She was seeking the pattern, having seen it enough times to crave more. But she was not in control of that. She simply had to remain open.
The woman's sisters and friends slowly separated from her, and they shared worried whispers about her less and less. Eventually, her husband took a job and Seattle and said he would return to move her there with him, but he never did. She didn't mind. He still supported her. Her bank account was alway full and never need replenishing. She had more than enough money for food and the occasional item of clothing she bought.
All the while, she continued her treks through the neighborhood. As time went on, people developed stories about the strange woman who limped up and down the streets, her eyes scanning back and forth, sometimes talking to herself. The stories ranged from true, that she'd been in a terrible accident that affected her mind as well as her body, to patently false, that she was a cold-blooded murderer who had done away with her husband. Most people felt sympathy for her, but some hated her for no reason other than she was different. One day, some kids in a car threw rocks at her, one large enough to leave a jagged gash in her forehead. She fell to her knees.
"Crazy bitch!" one of the kids sang out from the open car window as it sped away.
She stared at the concrete, tracing its web of cracks with her fingers. "The pattern," she whispered, knowing everything–the accident, her sisters and husband abandoning her, the cruelty of the world–was worth it.
Audrey and the Alien (a dialogue)
August 7, 2018 Robert Crisp	2 Comments
I don't remember writing this (no shock there), but I thought enough of it to keep it in my "story drafts" folder. I also have a folder called "lousy ideas," and the files in it are cringe-worthy.
Anyway, I have no idea if I'll do anything more with this, but I like the idea of a woman going to an alien therapist.
If I think about for too long, give it more than just a passing consideration, I start to question the whole system. And that's not good for anybody, especially my family. I have to think about them first, you know. I can't let anything happen to them.
It sounds like you're under a lot of stress.
Everybody is. I'm not special. I just keep my head down and do what I'm told, report to my job, and continue accepting things the way they are.
Your father didn't do that, did he? In fact, he rejected the way things were.
Yes…and he ended up disappearing. I try not to think about that, either. It's been five years.
He could be alive.
No. He's gone. I know that. Can we move on?
Of course we can, but we're not going to get anywhere if we don't discuss the more painful aspect of—
Everything is painful, Roger, but some things are pure agony, and I choose not to dwell on those.
You decided to come to me, knowing my specialty is Emotional Calibration. For the program to function successfully, you can't avoid the 'pure agony.'
You're not human. Jesus, I should have gone with a person.
Just because I'm not human doesn't mean I can't help, Audrey. In fact, I've helped many people, some of whom are your friends.
(sighing) I know.
And you decided to call me Roger.
Well, it's certainly easier than your real name, which I'm sure I couldn't even pronounce.
I could teach you, if you'd like.
No. That's okay.
All right. So, Audrey, if we're not going to talk about your father, would you like to discuss your job? Or perhaps your standing in the community? I understand you received a recognition last week.
Oh, that.
The Watcher (flash fiction)
August 3, 2018 Robert Crisp	Leave a comment
I'm slowly crawling out of the funk of a long-lasting, unexplained fever…and regaining my equilibrium in others ways after a difficult past few months. Writing hasn't been much of a priority. Today, I feel well enough to return to the keyboard, so I'm taking advantage of that.
I've been reading a lot of Joyce Carol Oates lately, and I see her influence on the following piece.
It wasn't enough that he could see her, he wanted to be close to her. He wanted to lean in, take a deep breath near her neck, and luxuriate in her scent; he wanted to meld his flesh with hers and disappear into the darkness forever.
Daniel slowly lowered the binoculars and squinted at her form, so far away. From this distance, she could be anyone. She was just another person sitting at the outside cafe, drinking a coffee. He couldn't see her delicate features, the gentle slant of her nose, the spark of her eyes. He couldn't see her lips curl in a secret smile or her brow furrow in worry.
"Excuse me, sir?"
Daniel turned at the voice, a flutter of panic in his stomach. The police officer wore a smile, but it was forced. The smile said, I'm trained to look like this when I approach people, even shifty-looking sons of bitches like you.
"Yes, officer?" Daniel said automatically. The binoculars suddenly felt awkward and heavy in his hands.
"May I ask what you're doing?" the office said. Even though he was in full uniform, including what looked like Kevlar under his short, his face was free from perspiration, and it was at least 90 degrees outside. Daniel had been sweating ever since he stepped out of his apartment, but that wouldn't deter him from his purpose.
"Bird watching," Daniel replied. He'd practiced this, of course. He care nothing about birds, but he'd memorized the local birds by studying various Internet sites. He could ramble off facts about cardinals and blue birds and even the migration patterns of geese.
"This doesn't seem like an ideal place for bird watching," the officer said, pleasantly enough. The radio on his shoulder squawked to life, and he reached out and turned down the volume. "I mean, standing here on the sidewalk downtown."
"You'd be surprised how many different species are here," Daniel said.
"Be that as it may, I'm going ask you to move along. The park isn't far from here."
Daniel gripped the binoculars. If he left, he could lose track of her, and who knows how long it would be before he tracked her down again? Lately, the girl had been changing her routine, and it frustrated (and tantalized) Daniel to no end.
"Sir?" the office prompted. His smile was gone now, and his voice carried a slight edge. "It's time to move on."
"Of course," Daniel said. "I wasn't trying to bother anyone. I just spotted a scarlet tanager and got excited."
"Where was this bird?"
Daniel smiled. He brought the binoculars back up to his eyes and focused on her. "Right over there," he murmured.
Random Lines
May 26, 2018 Robert Crisp	Leave a comment
Lately, writing has taken a back-seat to other things in life. That's the way of it. I found myself with some time today and thought, "All right, let's get crackin'." I wouldn't call the writing session a complete failure because I came up with some lines that made me laugh.
"You can't reason with Nazis!" the boy screamed, and by God, he was right.
He flourished, like a man named Steve flourishes in a crowd that's dangerously low on people named Steve.
She drowned in that crippled man's pond. I mean, what the hell? Who drowns anymore?
If you find a hat made of orangutan hair, keep it. Yeah, it's illegal, but it's worth it. You put that thing on when it's just you and your lady, you better to hang on to something, because it will get crazy in the bedroom.
And that's that. Maybe tomorrow will yield more substantial results. In the meantime, I'm thinking of taking one of the lines and turning into…well, something.
Glinda and Charley (a scene)
February 16, 2018 Robert Crisp	Leave a comment
I've given up trying to write traditional stories (at least, for now). Instead, I'm just letting the words do what they want. In this case, the words made me say, "What the hell?" Incidentally, the picture has nothing to do with the story. I just typed "weird" in the Flickr Creative Commons search bar and clicked on the one that made me laugh.
"Is there somewhere we can talk privately?" Glinda asked. She wasn't the Good Witch, or a witch at all. She was just Glinda, and she didn't know how to dress herself despite being thirty-three. She had a maid help her. The maid's name was Fuzzy. She was a cat, but a really smart one with a keen fashion sense and a remarkable vocabulary.
"Like the moon?" Charley suggested. He was fond of the moon and its wild temperature swings. He was also rather partial to radiation.
"The moon's too far," Glinda lamented.
"It's not that far if you travel with your imagination."
"Like Mr. Roger's?"
"Sure, if Mr. Roger's was a kick-ass space explorer."
"Mr. Roger's is plenty kick-ass without adding 'space explorer' to his already impressive resume," Glinda said. Her hair dragged the floor, and she suffered from excessive optimism, the kind that made Charley nervous.
"Whatever," Charley said. "Are we going to the moon or not?"
"Not. What I have to say can be said here. It's private enough."
"The bugs are listening."
"I'm not worried what a few bugs think, if they think anything at all." Glinda took a deep breath. "Ok, here it is. I'm worried you might not be real."
Charley rubbed his chin. The thought had occurred to him, too. It was troubling notion, that he might not be real. Glinda's realness was never in question. Was that strange or is that how things were supposed to go?
"Does it matter if I'm real or not?" Charley asked. "We still like each other."
"We do?" Glinda felt warm inside. She thought Charley kind of hated her.
"Well, we tolerate each other."
Glinda felt her insides clam up. She would never be the apple of Charley's eye, or of anyone's. The only creature that loved her was Fuzzy…maybe. Or maybe Fuzzy was just doing her job?
"Now that we've settled that, I'm off to check out the moon," Charley said. "Are you sure you don't want to come?"
"Yes," Glinda whispered.
"Toodle-oo," Charley said and blinked out of sight.
Glinda settled onto the floor and tried to cry, but she'd forgotten how. Or maybe she'd never learned in the first place.
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Posted insex & society
Why is Melinda Gates so obsessed with 'gender equality'?
The Bill and Melinda Gates Foundation will donate $2.1 billion to promoting women's rights.
by Anna Hitchings Jul 18, 2021 Jul 19, 2021 / 4 mins /
The Bill and Melinda Gates Foundation has donated billions in recent years to "gender equality".
A few weeks ago, the Bill and Melinda Gates Foundation (BMGF) announced it is venturing further than ever before in its quest to establish "gender equality" by committing no less than US$2.1 billion to the endeavour — more than half of which will be spent on contraceptives.
The Foundation, and Melinda Gates in particular, is well-known for its efforts towards sterilising as much of the female population as possible, particularly in Africa, India and other developing nations.
The remainder of the eye-watering sum will, according to the BMGF, be divided between accelerating "women's inclusion in leadership roles" (however that works) and strengthening "women's economic empowerment" by supporting "women's empowerment collectives, strengthen[ing] the care economy, improv[ing] women's financial inclusion, and reduc[ing] barriers to paid work" (whatever that means).
This is not the first time Melinda Gates has donated hefty sums towards pushing women out of the home and into the workplace.
In 2019, she pledged US$1 billion to expand "women's power and influence in the United States".
She loves throwing out broad, sweeping statements and philanthropic jargon without saying much of substance, that Melinda.
Her new press release is bursting with similar enthusiastic but meaningless statements like,
when women control their bodies and their futures, they unlock a cycle of empowerment that reverberates for generations to come
The world has been fighting for gender equality for decades, but progress has been slow. Now is the chance to reignite a movement and deliver real change
As an educated millennial, phrases like these sound embarrassingly archaic to me, not to mention cringeworthy as hell.
When I read such statements all I can think is, really? We're still doing this? We're still recycling outdated and debunked feminist narratives from the '60s?
As everyone ought to know by now, since making their escape from the shackles of home life 60 years ago, women have become steadily more miserable, disillusioned and drug-dependent.
This fact was made inescapably clear in a 2009 University of Pennsylvania study, which found that women have been growing unhappier since – surprise, surprise – the early 1970s (a fact Elle magazine described as "perplexing").
In her excellent 2019 book The Anti-Mary Exposed: Rescuing the Culture from Toxic Femininity, Dr Carrie Gress says,
…for all the so-called progress women have made, there is precious little evidence that any of it has actually made women happier. Divorce rates are still staggering, with 70 percent initiated by women; suicide rates are soaring; drug and alcohol abuse is unprecedented; STDs, particularly among women, are at epidemic levels, and depression and anxiety are everywhere. Women are not getting happier, just more medicated.
Turns out, most women are a lot happier being at home with their kids than working 80-hour weeks in corporate enterprises.
And yet we're constantly treated to Melinda Gates and her ilk spitting with rage about the under-representation of Fortune 500 female CEOs – while never stopping to ask how many women actually care about becoming one — and babbling on about the "wage gap", which has been debunked even by far-left publications like The Huffington Post.
But Melinda Gates' most sacred cow — as it is for virtually all loud and annoying feminists — is abortion and, by extension, contraception.
The Gates' obsession with these pillars of progressivism goes back decades. Their recent press release proudly states they have been fighting for "family planning" (read: abortion) and "women's health" (read: contraception) for 20 years. The Gates Foundation is even funding an online "Contraceptive Symposium" this month.
The family planning page on the BMGF website gives a lengthy account of their strategies and goals for "enabling women to make informed decisions about whether and when to have children", complete with photos of Foundation reps talking to people from impoverished countries, as an alleged means of tackling poverty.
However, as Nigerian pro-life activist Obianuju Ekeocha points out, most African women are far more interested in having access to basic commodities like food, water and an education than in contraception.
A little further digging into the Gates' history yields some surprising results.
For one thing, the United Nations Population Fund awarded their 2010 Population Award to the BMGF, with executive director Thoraya Obaid citing the Foundation as a "leader in the fields of global health and global development, particularly in promoting excellence in population assistance, including through the design of innovative, integrated solutions in the areas of reproductive health, family planning, and maternal and neonatal health".
For another, Bill said in his now-infamous 2010 TED talk that,
The world today has 6.8 billion people. That's headed up to about nine billion. Now, if we do a really great job on new vaccines, health care, reproductive health services, we could lower that by, perhaps, 10 or 15 percent.
I won't go into speculation about the relation between this and the Gates-funded Pfizer Covid-19 vaccine. My point here is that he makes clear his Malthusian mindset that the world would be better off with less people.
And it's no secret that the best way to achieve this is through sterilisation via contraception, or infanticide through abortion (that and keeping women out of the home and in the workplace).
China is our clearest and most recent example of this — to disastrous effect. They've finally begun to realise that their ageing population is becoming so top-heavy, they will soon end in economic and social collapse — hence the repeal of the one-child policy.
Ours is a sick society that values big salaries and high-flying careers over stable families and the lives of innocent children. Only a diseased social mind could come up with the "pussy hat" and the "shout your abortion" trend.
I fear that we will only spiral faster into this toxic morass unless we reject the Malthusianism of people like Bill and Melinda Gates and promote traditional families as the building blocks of society.
I've heard it suggested that the best thing we can do to rebuild our broken society is to get married and build large, stable families.
I know that, given the chance, that's exactly what I'll be doing.
Anna Hitchings
annahitch@me.com
Anna Hitchings is a freelance writer based in Sydney. More by Anna Hitchings
Tagged: abortion, Bill and Melinda Gates Foundation, Bill Gates, contraception, feminism, Melinda Gates, population, population control, wage gap, women's health


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Q: Dynamically changing a NSWindow's contentViewController I have an NSWindowController and an NSViewController, both configured in a storyboard.

*

*When I set the contentViewController in Interface Builder, everything works as expected.

*When I set the contentViewController programmatically in windowDidLoad everything works as expected.

Now I'm trying to update the content view controller in response to a toolbar button click (below).
@IBAction func toolbarButtonClicked(_ sender: Any) {
    contentViewController = storyboard?.instantiateController(withIdentifier: "VC") as! NSViewController?
}

This assignment causes viewWillAppear to be called on the view controller, but at that point the content view doesn't have a window assigned.
Why is this? Is it possible to dynamically change a window's contentViewController like this?

A: It looks like:

*

*When the content view is configured in storyboard or windowDidLoad, the view already has a window by the time viewWillAppear gets called, i.e. when the window itself appears.

*When the content view is set after the window has appeared, viewWillAppear gets called to indicate that the content view will be added to the window; the view has no window until viewWillLayout is called.

I was using the window to access the current document, so my solution was to access the document before updating the content and use that to configure the content view controller.


One of the periodic reports from TfL has been released with details of ongoing network upgrades across the networks it controls over the past few months. If you've ever wondered what goes on when the lines are closed at weekends, this will inform you.
The planning application for the rebuild of the ticket hall is due to be submitted by the end of the year.
They completed the primary construction works in late September. More than two-thirds of the pre-cast platform sections have been installed and casting of the lining wall and column encasement continues on schedule. The blockwork to create the internal walls for the rooms in the new station and construction of the eastern superstructure are now underway.
Construction work has started on the internal walls to form the rooms in the new station. Construction of the eastern and western service lift shafts and emergency stairs was completed in September. Installation of the architectural ceiling in the station ticket hall continues, with 80 out of 92 sections complete.
The final fit-out of four new passageways continues during engineering hours. This includes the installation of the flooring and electrical equipment as well as tiling the passageway walls.
80 percent of the new tunnels for the station upgrade has been completed, and waterproofing of the new tunnels has begun ahead of schedule.
At the new Cannon Street entrance, they have completed the large-scale excavation of the new station box. The next phase involves starting the lift shafts for the new station entrance. Preparatory works at the Northern line platform are almost complete.
The exceptionally delayed new entrance to the Waterloo & City line is still due to open by the end of this month.
All remaining station modernisation works will be finished by the end of December, with the project close-out including property refurbishment, reinstatement of the roadway and bus station by mid-2019.
Two new escalators and a new lift between the Bakerloo and Elizabeth lines have been installed. The installation of vitreous enamel wall and ceiling panels is progressing.
For the signalling upgrade, they have competed 120 out of 192 in-cab installations to 18 (out of 33) engineering vehicles, and have successfully run one of these in test conditions.
They have also upgrade 24 of the 46 signal control rooms.
performance and provide a more comfortable journey. It includes an overhaul of door locks, saloon doors, saloon seating and flooring, and replacing central wiring.
to complete the project in 2022.
Progress is being made on completing the stations and testing their systems as well as completing the installation of the rail system in the central tunnels to facilitate a period of intensive underground testing of signalling systems, train and rail infrastructure.
Award of the contracts for enhancement works on six western surface stations is progressing, and enabling work for these station upgrades is continuing with significant works.
At Camden Town, four sets of deep Tube points had been renewed, including 100 metres of new track layout.
Moorgate Station – I visited Moorgate Station last Wednesday and was able to see the new lift for the Northern Line through a glass panel in shuttering.
I then went up to the Great Northern City Line which is directly above the Northern Line and even has escalators for interchange. But there was no sign of any work to install lift access.!
It seems according to the person who runs SFL site (Step Free London) Moorgate finds itself in a civil war between the DFT who operate Northern City Line and Northern Line run by TFL and Mayor as to who funds lift access ! ( in other words who builds a hole in the wall so lift can stop at that level ….! ) .
Will Circle Line, Metropolian Line, Hammersmith & City Line and District Line could introduce Night Tube services. Once the signalling and track upgrades have been completed. Same with Bakerloo Line that Night Tube could also be introduced. DLR also operates their own services at night. And parts of the London Overground routes could also operate at night such as the North London Line, West London Line, Lea Valley metro services (Liverpool St-Cheshunt, Chingford and Enfield Town), Euston-Watford Line and Gospel Oak-Barking Line.
A Euston to Watford LO night sevice would be rammed, might have to put on extra trains !
Perhaps you are right James.
A Euston to Watford LO night service would be rammed, might have to put on extra trains !


Excellent Tofu & Snack LTD.
Appetites are a strange thing. Some days you can go hours and hours until you find yourself hungry, while on other days you can't seem to find an end to the munching. This dietary conundrum is even more pronounced when it comes to food bloggers. While some only seem to play with their plate, many more seem to swallow it by the dump truck. The interesting part of this really starts to show when I travel; even more so when I head to a place like Vancouver where I've established some ties to the food community. This inevitably means food…and more food and more food.
Take this stop on Saturday night after landing in Vancouver. With our feet barely making prints on tarmac and our luggage still waiting behind the scenes, we were already in discussions about food. That's right, our weekend tour guide and local blogger Kim (I'm Only Here for the Food) had post-plane dessert plan. Tofu, at the aptly named Excellent Tofu & Snack LTD.
A small, dive-like shop, Excellent Tofu is all business; offering an assortment of house made (that's right, house made) silken tofu to fill your tummy. Just in case you are craving more when you arrive, you can also pick off a short menu of standard Asian appetizers. With seats along the bar and wall, we added third chair to the last table available and got to business. Right away you could smell the restaurant mixing up tofu and turning around in my chair I saw hoses, buckets, and heating elements. Nothing says a good time like fresh food, so it must be the same with tofu right!
I should clarify that there really isn't an assortment of the tofu, rather, the custard-like base stays the same and the toppings are what you change. From tapioca to maple syrup, you can find a lot of toppings. As well you can get your order cold or warm. The tofu comes unsweetened which may not suit those with a sweet tooth, but don't worry, there are bottles of liquid syrup (plain and ginger) for the diner to adjust to their liking. I quite like this idea as it allows for you to have a bit of control in how bad or good the treat will be. After a few minutes of contemplation, we settled on Grass Jelly, Red Bean with Coconut Milk, and Black Glutinous Rice; all of which we asked to be warm.
The toppings from all three were good and except for the rather bland jello-like grass jelly, didn't need any additional sugar. None of the three toppings were offensive in any way, which I think is half the battle for those who've never encountered them before. The ginger sugar syrup would be my favourite of the two as it gave me some baking ideas. The tofu was perfectly smooth and creamy and really did make for a nice change in dessert choices. With prices around $3.50 for each bowl, it's a pretty reasonable snack and worth the price of admission.
I was quite relieved that you and Sarah liked it. Not only this can be a bit of an acquired taste; also stakes here were high. After all, I had to, ahem, make a good impression! 😀 Looking forward to your other post!


What documents do I need to provide you with to complete my DBS identity check?
We will need sight of 3 original documents to confirm both your name and current address. The following documents are acceptable.
Your address: This must be a document sent by post to your address and must be dated no earlier than 3 months before the check is carried out by TSE (exceptions listed below). One or two of these documents can be used provided they are not from the same institution.
We will check and process the DBS after 1st June (3 months before the course commencement e.g. if the check is carried out on 1st July the document must be dated no earlier than 1st April.
I do not receive any utility bills or bank statements through the post, what should I do?
Please request a one-off printed statement or bill to be posted to you from your bank/credit card company or service provider. We are unable to accept documents downloaded from the internet and must have sight of an original statement which has been posted to you.
When do I need to apply for a DBS?
You should register online for your DBS before 1st June, or as soon as you have been offered a place on the course if later. We will provide you with a document which will take you step by step through the DBS process, along with the website link to register your details and start the process. Once you have supplied us with the documents we need to check your identity, we can then confirm to the DBS authorities that we are happy with the documents you have provided, and you will be issued with a DBS certificate.
I already have a DBS; why do I need another one?
Teach SouthEast is responsible for ensuring all eligibility checks are carried out and the trainee is suitable for work with children. This is regardless of any previous DBS checks. TSE will then inform your training school that the checks have come back clear.
Should I enrol for the Update Service?
We recommend that trainees register with the updates service as this will mean you are not required to reapply for a new certificate for each school that employs you in the future. Users of the online DBS application service will be given the opportunity to subscribe to the DBS update service on receipt of their electronic (e) reference number or when their new certificate is issued. You only have 19 days from the date of issue of your certificate in which to subscribe. Please note that if you apply for the update service you will be liable for the annual fee of £13.
Further information on how to apply for the update service can be found at https://www.gov.uk/dbs-update-service.
I have lived overseas during the last 10 years, will I require any additional checks?
Yes, all trainees who have lived overseas during the last ten years are required to obtain a police check from their previous country of residence. This is in addition to the standard DBS check.
I will have some disclosures on my DBS, how will this affect my application?
Any disclosures will be assessed on an individual basis in strict confidence within 28 days of your receipt of the DBS certificate. A risk assessment will be carried out and the result notified to you in writing. If you are aware of any information which may affect your application, please notify us immediately.
When should I take the skills tests?
I am worried about passing the tests. Is there any help available?
Teach SouthEast also host numeracy & literacy support sessions for trainees who feel they may require additional help. Please contact us for further information.
You are strongly advised to practise the tests before taking them to familiarise yourself with the functionality of the tests.
For more information on the specification and how to access sample tests, please follow the link to http://sta.education.gov.uk/.
I have special needs: are there any special access arrangements for sitting these tests?
You may be eligible for special access arrangements. Visit the website at http://sta.education.gov.uk/professional-skills-tests/access-arrangements for more information.
What happens if I fail the skills tests?
As of 14 February 2018, candidates will have unlimited attempts to achieve a test pass. Candidates will be able to book three tests per subject, free of charge. A charge will be applied from the fourth test attempt per subject.
Before booking a resit you should consider any areas of weakness which were highlighted on the score report of your previous attempt.
We recommend that you allow plenty of time to revise before you resit a test. Practice materials and guidance to help you prepare are available on the http://sta.education.gov.uk/ website.
I would like to get my skills test completed early. Is this possible?
Yes. You can take your skills tests once you have evidence of having submitted your application through UCAS Teacher Training. You can book your tests in advance of this, as long as your UCAS application is submitted before attending the test centre.
I was educated overseas, how will this affect my application?
Your overseas qualifications will need to be sent to NARIC (National Academic Recognition Information Centre) who will complete a statement of comparability. This process can be lengthy, so apply as early as possible. For further information visit the NARIC website: www.naric.org.uk.
What should I do if I don't have English / Maths GCSE equivalent?
I will be finishing my degree this summer so can't provide certification of my degree class. Will this be a problem?
No, this is not a problem. You will need to inform Teach SouthEast of your degree classification as soon as it has been awarded and present your original degree certificate once you have received it.
I can't locate my qualification certificates. what should I do?
If you have misplaced your degree certificate, you will need to contact your University to obtain a certified letter confirming you degree classification.
My conditional offer includes a requirement to complete an SKE. How long should the course be?
The duration of an SKE course will be stipulated in your conditional offer letter with course lengths varying between 8-28 weeks. The start date of an SKE is your own choice, however, please note that courses must be completed prior to commencing your ITT training in September.
Can I choose my own SKE provider?
Yes. You are free to find a suitable course from any provider subject to our approval. We do recommend the TES Institute which offers fully online courses of a variety of lengths. https://www.tes.com/institute/ SKE courses are fully funded by the government and you may be eligible for a training bursary of up to £7,200 to support you throughout the course.
I have a disability, how will Teach SouthEast support me?
As a team, Teach SouthEast will support you to fully access the course taking into account any disabilities you may have. Please ensure we are fully aware of any special needs and it will be arranged that you meet with a senior member of the team to discuss how best we may support you.
I am a salaried trainee. What difference does this make to the admin process?
Please contact your employing school as soon as you can. They will be responsible for obtaining your DBS and Fitness to Teach checks, therefore it is very important that you liaise directly with them as early as possible.


Spread across three tower blocks it will house 105 residential units, with a commercial floor on ground level. The basement will host a range of amenities including swimming pool, sauna, spa and gym. Formerly home to a historic petrol station and a famous Banksy graffiti piece.


text:
Commercialisation of Education
Topic is in the paper instruction
A world of work
Angels in America
Brown v Board of Education
Caring About Our Environment
Causes of Obesity in America
Childhood Obesity in America
CRITICAL DISCUSSION OF APPLICATION OF TAYLOR'S PRINCIPLES Name: Class: Name of school: City: State: Date: Introduction In the world of work, there have been efforts of seeking organization such that there can be a maximum production with high efficiency. Among the entities that influence the set up of work, the principles of Taylor have been on the front line. There has been much organization of work in agreement with Taylorian principles in a bid to gain maximally. On the same note, personnel departments and academics keep themselves busy with tasks such as training and adjustment of the workforce. In this paper, there is a critical discussion of how there has been the organization of work following the principles of Taylor. There are deliberations of the tasks with which personnel departments and the academics busy themselves. There is the analysis of how Taylorism dominates the production world. The principles There is much organization of work in line with the principles of Taylor. This statement may not make sense to a person who does not recognize Taylor himself. Taylor was a mechanical engineer in America. In the peak of his career, he sought to bring efficiency in the industrial world, (Kai-Ping, Jane, Sheng & Mei-Ju, 2013, 79). Taylor was among the earliest management consultants who worked hard to achieve sanity in the world of work. Putting his efforts together, Taylor came up with a useful book which has been in use in the industrial world, famously known as the principles of scientific management. It is those principles of scientific management which managers in workplaces have sought to align to, in a bid to ensure efficiency in the
Free Topic is in the paper instruction Essay Sample


text:
Orhun H Kantarci, Brian G Weinshenker
Multiple sclerosis (MS) is the prototypic idiopathic inflammatory demyelinating disease (IIDD) of the central nervous system (CNS) (Table 20.1).1 The clinical manifestations, prognosis and pathological features vary, both amongst entities within the broad spectrum of demyelinating disease and amongst subtypes of MS.2 MS is usually classified based on the temporal course of disease; the most common form is characterized by an initial relapsing-remitting course that ultimately evolves into a progressive disease. A variety of neurological functions are affected during these relapses depending on the location of the lesion. During and between clinical relapses, magnetic resonance imaging reveals CNS white matter lesions of different stages, most evolving without symptoms. While relapses and new inflammatory lesions detected on MRI become less frequent, and even scarce over time, an insidious course of worsening neurological function ensues characterized by prominent progressive axonal loss (secondary-progressive MS). Progressive axonal dropout apparently begins at a very early stage, when the clinical disease is still regarded as relapsing remitting. About 15% of cases, despite occasional relapses, remain disability-free (benign MS). Some cases present with insidious neurological dysfunction, most commonly as a myelopathy from onset without any clinical symptoms of acute relapses (primary progressive MS).
Cytokine Gene Polymorphisms in Multifactorial Conditions
0849336198, 9780849336195
Immunology and Microbiology(all)
Pharmacology, Toxicology and Pharmaceutics(all)
Fingerprint Dive into the research topics of 'Multiple sclerosis'. Together they form a unique fingerprint.
Multiple Sclerosis Medicine & Life Sciences
Recurrence Medicine & Life Sciences
Chronic Progressive Multiple Sclerosis Medicine & Life Sciences
Neurology Chemical Compounds
Demyelinating Diseases Medicine & Life Sciences
Central Nervous System Medicine & Life Sciences
Spinal Cord Diseases Medicine & Life Sciences
Kantarci, O. H., & Weinshenker, B. G. (2006). Multiple sclerosis. In Cytokine Gene Polymorphisms in Multifactorial Conditions (pp. 289-304). CRC Press.
Multiple sclerosis. / Kantarci, Orhun H; Weinshenker, Brian G.
Cytokine Gene Polymorphisms in Multifactorial Conditions. CRC Press, 2006. p. 289-304.
Kantarci, OH & Weinshenker, BG 2006, Multiple sclerosis. in Cytokine Gene Polymorphisms in Multifactorial Conditions. CRC Press, pp. 289-304.
Kantarci OH, Weinshenker BG. Multiple sclerosis. In Cytokine Gene Polymorphisms in Multifactorial Conditions. CRC Press. 2006. p. 289-304
Kantarci, Orhun H ; Weinshenker, Brian G. / Multiple sclerosis. Cytokine Gene Polymorphisms in Multifactorial Conditions. CRC Press, 2006. pp. 289-304
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title = "Multiple sclerosis",
abstract = "Multiple sclerosis (MS) is the prototypic idiopathic inflammatory demyelinating disease (IIDD) of the central nervous system (CNS) (Table 20.1).1 The clinical manifestations, prognosis and pathological features vary, both amongst entities within the broad spectrum of demyelinating disease and amongst subtypes of MS.2 MS is usually classified based on the temporal course of disease; the most common form is characterized by an initial relapsing-remitting course that ultimately evolves into a progressive disease. A variety of neurological functions are affected during these relapses depending on the location of the lesion. During and between clinical relapses, magnetic resonance imaging reveals CNS white matter lesions of different stages, most evolving without symptoms. While relapses and new inflammatory lesions detected on MRI become less frequent, and even scarce over time, an insidious course of worsening neurological function ensues characterized by prominent progressive axonal loss (secondary-progressive MS). Progressive axonal dropout apparently begins at a very early stage, when the clinical disease is still regarded as relapsing remitting. About 15% of cases, despite occasional relapses, remain disability-free (benign MS). Some cases present with insidious neurological dysfunction, most commonly as a myelopathy from onset without any clinical symptoms of acute relapses (primary progressive MS).",
author = "Kantarci, {Orhun H} and Weinshenker, {Brian G}",
booktitle = "Cytokine Gene Polymorphisms in Multifactorial Conditions",
publisher = "CRC Press",
T1 - Multiple sclerosis
AU - Kantarci, Orhun H
AU - Weinshenker, Brian G
N2 - Multiple sclerosis (MS) is the prototypic idiopathic inflammatory demyelinating disease (IIDD) of the central nervous system (CNS) (Table 20.1).1 The clinical manifestations, prognosis and pathological features vary, both amongst entities within the broad spectrum of demyelinating disease and amongst subtypes of MS.2 MS is usually classified based on the temporal course of disease; the most common form is characterized by an initial relapsing-remitting course that ultimately evolves into a progressive disease. A variety of neurological functions are affected during these relapses depending on the location of the lesion. During and between clinical relapses, magnetic resonance imaging reveals CNS white matter lesions of different stages, most evolving without symptoms. While relapses and new inflammatory lesions detected on MRI become less frequent, and even scarce over time, an insidious course of worsening neurological function ensues characterized by prominent progressive axonal loss (secondary-progressive MS). Progressive axonal dropout apparently begins at a very early stage, when the clinical disease is still regarded as relapsing remitting. About 15% of cases, despite occasional relapses, remain disability-free (benign MS). Some cases present with insidious neurological dysfunction, most commonly as a myelopathy from onset without any clinical symptoms of acute relapses (primary progressive MS).
AB - Multiple sclerosis (MS) is the prototypic idiopathic inflammatory demyelinating disease (IIDD) of the central nervous system (CNS) (Table 20.1).1 The clinical manifestations, prognosis and pathological features vary, both amongst entities within the broad spectrum of demyelinating disease and amongst subtypes of MS.2 MS is usually classified based on the temporal course of disease; the most common form is characterized by an initial relapsing-remitting course that ultimately evolves into a progressive disease. A variety of neurological functions are affected during these relapses depending on the location of the lesion. During and between clinical relapses, magnetic resonance imaging reveals CNS white matter lesions of different stages, most evolving without symptoms. While relapses and new inflammatory lesions detected on MRI become less frequent, and even scarce over time, an insidious course of worsening neurological function ensues characterized by prominent progressive axonal loss (secondary-progressive MS). Progressive axonal dropout apparently begins at a very early stage, when the clinical disease is still regarded as relapsing remitting. About 15% of cases, despite occasional relapses, remain disability-free (benign MS). Some cases present with insidious neurological dysfunction, most commonly as a myelopathy from onset without any clinical symptoms of acute relapses (primary progressive MS).
BT - Cytokine Gene Polymorphisms in Multifactorial Conditions
PB - CRC Press