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Founded in 1885, Tamesis is one of the most active and popular sailing clubs in south west London. Our clubhouse in Teddington is on the first non-tidal reach of the River Thames between Kingston Bridge and Teddington Lock. We provide racing for five different dinghy classes every Sunday morning throughout the year and handicap races on Thursday evenings in the summer. We also hold a number of Regattas and Special Races (see Events page).
We are a friendly, family club offering excellent facilities, sail training, and a lively social programme. New members are welcome. Please visit us any Sunday morning if you would like to join or find out more about us.
Tamesis Club is local. We are not in the middle of the countryside or down on the coast, but right in the heart of South-West London. We are situated in Teddington just off Broom Road, are only a 10-15 minute walk from Hampton Wick station, or a 10 minute walk from St. Marks Road bus stop. There is also a large car park for those driving.
See Location page
The sailing
The club exists mainly for dinghy sailing and racing which is varied and fun at Tamesis. The river location offers its own unique challenges and wind conditions can vary from a light breeze (for those of us wanting a more sedate race) to strong winds (for those of us wanting a real challenge).
There are ample opportunities to crew, and you definitely don't need to own a boat to be able to sail at Tamesis (many members don't).
Sailing is also for all ages. We have children as young as eight sailing as part of the Cadet Class (which meets on Saturdays throughout the summer), and also racing with the adults on Sundays all year round and one of our regular Laser members is about to turn 84!
We are a very friendly and open club and welcome all visitors and prospective members. Once you become a member (sailing or social) you will get to meet and make friends with many others through the sailing and post race lunches, dinners and other social events. All at Tamesis have an interest in sailing, socialising, and supporting each other.
The club is not solely about the sailing. In addition to lunch every Sunday and supper on Thursday evenings during the summer, we have many other social events throughout the year, including dinners, quizzes, BBQ's, summer parties, evening talks with supper, and much more.
There are also groups within the Club that use the clubhouse, such as the Bridge group on Wednesday evenings.
Phil's Bar
Named after our late great Honorary Club Architect, Phil England. Phil was a stalwart of the club for over half a century and we have him to thank for how the clubhouse is today, the key feature of which is Phil's Bar which is at the busy end of the Clubhouse by the entrance to the lawn.
Phil's bar serves a wide selection of wines, spirits and soft drinks and has REBELLION BEER on tap – all at very reasonable prices.
The club lawn, next to the clubhouse veranda, is an ideal place to bring the family to relax, have a bite to eat, and watch the sailing.
Junior Sailing
The club is suitable for all ages and 8 – 16 year olds form their own group called the Junior Sailors. The Juniors have their own mini-clubhouse (overlooking the lawn) and sail together on Saturdays throughout the summer, and often on Sundays with the rest of the club.
The Boat Park and Boat Shed
For those who wish to own and maintain a boat there is plenty of room at Tamesis. The Boat Park has some covered storage for those boats that need it, and a storage area for road trailers. The Boat Shed provides a convenient place to work on your boat whether that is to add new fittings or varnish a wooden deck. Additionally, many members at Tamesis are highly experienced in boat maintenance and are always willing to lend a hand and give advice.
How the club is run
Tamesis is run entirely by its members. The elected flag officers and Committee of Management, chaired by the Commodore, are responsible for overall management. Racing is organised by the Sailing Committee, chaired by the Rear Commodore Sailing, and social events and catering are supervised by the House Committee, chaired by the Rear Commodore House. There is a class captain for each of the dinghy classes and the Offshore Group. All are volunteers. Individual members do race officer and patrol boat duty twice a year.
It was the Romans who gave the Thames the name Tamesis, "a combination of Isis, the old name for the river from its source to Dorchester, and Thame, the tributary it meets near Dorchester". (From The Thames by Paul Atterbury & Anthony Haines, ISBN 1-84188-175-9, published by George Weidenfeld & Nicholson in 1998).
"I walk my beat before London Town, Five hours up and seven down, Up I go till I end my run, At Tide-end-town, which is Teddington." (from The River's Tale by Rudyard Kipling).


Sleek and shiny are all the rage this season. Follow fashion into any season with this belt. Thinly woven shimmering silver mesh winds around to leather-look closer straps and square silver metallic buckle. You choose white or black, dark or light to accent your every whim. Fits standard belt loops.
1 1/8th" wide silver back with white or black leather-like lengths to silver metallic buckle.


Constant Conversations: Hold Your Horses!
What was even more beautiful was the price: $9.95, reduced from $138! Never mind the fact that they actually had my size. After school, Quickly with friends, shower, and dinner, I convinced my mom to drive us to our nearest Anthro so we could find them.
Long version: Entering my local Anthro around fifteen minutes before closing, my mom and I fast-walked towards the sale room in the back. Much to my despair, I couldn't find them in the sale section. My mother was far more prudent than I, and searched the sale rack near the dressing rooms. Et voila! She found them! Except—they didn't have my size. They only had one 28 and a bunch of 29's and 30's. In other words, about 4-6 sizes too big (my size generally ranges from 24-26, or 00-2, depending on whether I want a skinny skinny fit or a more slouchy one). My mom told one of the Anthro girls that online it said there was limited availability of size 26. The girl said to search the sale section, in case someone put it back there. I was crestfallen. I had just come from the sale section; I knew there were none. Combing through the racks dejectedly once more, I searched for my size and admired the softness of the 100% cotton denim. Perhaps it could shrink to my size…? I sighed, and then wandered back to the sale room, where my suspicions were confirmed by my mom: no Holding Horses Patchwork Gable Boyfriend size 26 on the rack. All of a sudden, the Anthro sales associate popped out of the back room of the sale room with a pair of jeans in her hands. "Here, I found the size 26." My mom thanked her elatedly and shooed me off to the dressing rooms. Final test: the fit. I pulled them on, and—perfection. They were a little oversized in the waist, it's true, and a size 25 might've been better, but they were perfect for that comfy, slouchy boyfriend jean feel. My mom came in to see them, and then whisked us off to the cash register, where we bought the jeans for a whopping total of $10.71 and brought them home.
In other news, I now have about 4 new pairs of jeans that I haven't worn yet. Not to mention the new pair of BB Dakota shorts, the matching laser cut tank, and the Alternative Apparel tank, all from Karmaloop. I know I shouldn't tag away from Twitter, but... #shoppingaddictproblems.
Hey there! love those jeans,so boyish yet chic!


Title I, Part A is a federal program that serves the unique needs of children K-12 who struggle to learn. Title I programs and services provide customized instruction and curricula that helps these students meet academic standards and take an active, engaged interest in what they learn. As the oldest and largest federal education program, Title I programs build equity of opportunity for children whose struggles often keep them on the academic sidelines.
Go to the OSPI School District Report Card to learn more about our demographics, test scores and enrollment in the Marysville School District. Once you are in the OSPI website for the Marysville School District, use the drop down menu to choose an individual building's report card. Hard copies of this information is also available at all the school building offices and the main District Office.


Videos, directed, filmed and edited.
Here are 2 videos I made capturing some stunning aerial views down by the river, check out the landscape!
The latest music video fro The High Breed, its called Weirdo, and its a bit weird, which suited my style and this is what we ended up with….
Who is he..? I dont know… i didnt find out in the end, but we did go looking in some caves…… this is all we could find….
I had a chance to test out the DJI Spark… some stunning clips!


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How a counselor shortage is hurting students struggling with anxiety, depression
School counselor retention was already a problem before the COVID-19 pandemic, according to mental health experts. They said it's only gotten worse in recent years.
By Nicole Cortes, Zioni Moore and Whitney Souffrant
This story was published to USA TODAY on April 21, 2022.
It's a typical school day at Miami Lakes Educational Center located in this northwestern suburb of Miami. Kids are rushing to and from classes, people are eating in the cafeteria and Gabriella Fuster, an 18-year old senior, enters the bathroom. She walks into a stall, closes the door behind her.
And she cries.
"I'll hide in there for a good 10, 15 minutes," Gabriella said.
Now, as most students have returned to in-person learning following the quarantine restrictions issued during the worst of the COVID-19 pandemic, taking a few minutes to cry in the bathroom has become the norm at her school, Gabriella said. It's so common that when students walk back into the classroom and tear tracks are still visible on their faces, teachers immediately understand what happened.
"The teachers usually know that you weren't just messing around," Gabriella said.
Gabriella Fuster. Photo by Melissa Noda
The bathroom has become a substitute for a counseling office partly because, like many schools around the country, Miami Lakes is struggling to afford, and hire, enough mental health counselors to help students. Counseling experts say that was a problem before the pandemic and was only made worse during the lockdown because students were isolated at home, their friends and family were getting sick and dying from COVID, and they had no one to turn to and nowhere to go.
Students are now facing the added anxiety of returning to in-person classes, some entering a brand new environment with people they've only seen on their Zoom screens.
"We've definitely seen students across the nation express more feelings of stress and more feelings of anxiety," said Tinisha Parker, executive director of student services at Gwinnett County (Ga.) Public Schools and the former chair of the American School Counselors Association. "Just feeling kind of out of control feelings of fear, of the unknown."
Congress and state legislatures have tried to help by allocating millions of dollars to hire more mental health counselors, but schools have faced their own struggles. Some can't find enough qualified counselors and others worry about hiring new staff with money that's only designed to be short term.
For schools in under-resourced communities, finding enough counselors has always been a challenge. The American School Counselor Association recommends that schools have no more than 250 students per counselor. Only 4.2% of schools located in city centers meet that recommendation, while suburban schools are twice as likely (9.8%) to do so, according to a report from the University of New Hampshire Carsey School of Public Policy.
"When you don't already have resources to be able to support what was happening before the pandemic, and you don't pump anymore into the communities to support those after the pandemic, then those gaps are going to increase," said Kent Butler, a professor in counselor education at the University of Central Florida who holds a Ph.D. in educational psychology.
Struggle to find enough counselors
One of the biggest challenges facing schools is finding enough qualified counselors to hire.
Despite government funding, there's a supply-versus-demand issue in the school counseling field that existed long before COVID-19 hit.
Careers in mental health counseling are expected to grow 23% in the next decade, according to the U.S. Bureau of Labor Statistics. But there aren't enough students in the pipeline to meet that increased demand, partly because of the extensive training and multiple degrees and certifications required to become a counselor and because many programs require students to perform a year of unpaid training, an insurmountable economic barrier for many.
That scarcity is so severe that Nikki Poindexter Ham, the president of the Maryland School Counselors Association, has doubled her recruitment efforts over the past year and a half. She has increased the number of visits she makes to high schools and colleges where she encourages students to become counselors.
She's doing that at a time when more Americans have become more sensitive to mental health as a legitimate problem that requires professional help. About 87% of Americans say that mental illness is "nothing to be ashamed of," according to a May 2019 survey from the American Psychological Association.
And yet, schools are still struggling to find enough counselors.
Jennifer Rothman is a senior manager at the National Alliance of Mental Illness (NAMI), the nation's largest alliance of local mental health organizations, but even she has struggled to find a counselor for her daughter.
"It can be very difficult," she said. "There are shortages all around for that."
In Miami-Dade County, Florida, the school district used $14.2 million to hire 20 mental health coordinators and 100 part-time mental health professionals to respond to the growing mental health needs of its students due to the pandemic. And it has plans to hire an additional counselor for each school in January.
But the district remains far below the ratio of one counselor for every 250 students recommended by the American School Counselors Association. At the start of the 2021-2022 school year, Miami-Dade's ratio was 454 to 1.
"Miami-Dade County Public Schools strives to meet the mental health needs of students in a timely fashion," the district said in a statement. "School counselors are onsite daily, while school psychologists, school social workers, and mental health coordinators spend one day a week at a given school."
Counselors could be allowed to do more
In addition to the shortage of counselors, Butler says there's another problem.
"School districts don't know how to use a school counselor," said Butler, the counseling professor at UCF. "We don't utilize their God-given skills."
School counselors generally fall into three categories. Some help students with their day-to-day academics, some help them with college applications and scholarships, and guidance counselors are dedicated to the well-being of students, including their mental health, family problems, or addictions.
But Butler said they're generally not allowed to cross over into different areas. So, for example, academic counselors are not allowed to discuss family or legal problems with their students, he said. He also said many schools use counselors for administrative work, such as class scheduling, which limits their time counseling students. That means students are left with fewer people to turn to for mental health counseling.
To address these issues, Butler believes schools need to allow academic counselors to provide mental health counseling, so long as they're qualified to do so. In addition to that, schools need to assign only counseling tasks to their counselors.
"If an academic counselor is competently trained...to provide mental health care, then they should be able to utilize their expertise to provide that service," he said.
Districts finding creative solutions
To address the shortage of counselors, many districts around the country have been forced to get creative.
In Broward County, Fla., the school district started its own counselor training program. Using a $2 million federal grant, the school trained 20 social workers and mental health counselors to work in Broward schools over the past year.
In Gwinnett County, Ga., schools are placing a higher emphasis on the use of S.E.L., or social-emotional learning, a program that teaches students and teachers the basics of mental health and how to identify problems that need to be referred to a counselor.
"Every adult in the building has a part of supporting S.E.L, whether you're doing it formally through your instruction, or integrating it through your instructional strategies, or whether you are modeling it as a bus driver or as a custodian or as a cafeteria worker," said Parker, the Gwinnett County administrator.
Several school districts around the country are considering allowing students to take a "mental health day" as an excused absence. That is already in place in Oregon, Illinois and parts of Maryland, and more schools have become interested following the pandemic.
In Maryland, several school districts have been encouraging students to counsel other students. Poindexter Ham, the president of the Maryland School Counselors Association, said those peer counseling programs help offset the lack of professional counselors and provide students with someone they can relate to.
"It's identifying...teens to really be that connection and that support for other teens and really reaching out and helping," Poindexter Ham said.
All these efforts may one day improve the lack of access to adequate mental health services plaguing the nation's schools, but students say they're not yet seeing results.
Gabriella, the Miami Lakes senior, said she sees her classmates struggling constantly. She tries to help when she can, but she's also aware that she's not a trained therapist. So she's hoping that students in her school, and others, one day get the help they truly need.
"A lot of kids at my school...suffer from intense anxiety," she said. "And when I'm feeling like I want to cry in the bathroom...I would like to be able to go to the counselor's office and feel safe and secure and cry in there instead."
Cortes, Moore and Souffrant are high school students at Luella High School in Locust Grove, Ga., North Cobb High School in Kennesaw, Ga., and Miami Lakes Educational Center in Miami. They were participants in Youthcast Media Group's reporting workshop on pandemic student mental health in Fall of 2021. YMG student Melissa Noda contributed to this story.
#counselors #mentalhealth #Recentstories #Supportgroups

redpajama_set_name: RedPajamaCommonCrawl


There are so many types of hair extensions on the market, so how do you know which origin to choose from? There is Brazilian Malaysian, Indian, Peruvian, Mongolian, and the list goes on. What's is the difference? Well we are here to share with you what the differences are in our three origins we sell. Knowing the differences will help you choose the right hair extensions to purchase.


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Cable Operators Employing Preventative Care Maintenance
By K.C. Neel
As the competition for pay TV customers intensifies, keeping existing subscribers satisfied has become even more important — and complicated — for distributors.
But operators are currently swimming in a sea of data, making it difficult create a meaningful proactive plan, according to Ryan Pellet, senior vice president of strategy and service for Nexidia, an Atlanta-based phonetic search technology firm.
Such independent variables as network reliability, customers' payment history, rate hikes and the competitive landscape affect issues that operators want to address, including downgrades, disconnects and net promoter scores. Complicating matters is the fact that those variables can differ in each market.
A new effort pushed by software companies, called "proactive care," requires proritizing these independent factors to determine how best to interact with a customer. "Big data can take those variables and determine a proactive action to retain that customer," Pellet said.
But it can be tricky, Tapan Dandnaik, senior vice president of customer service and financial operations for Mediacom Communications, said. Each market presents its own set of variables, which can vary widely. Big data can sort out how those issues are affecting the company as a whole.
There is no way to completely eliminate the need for customers to contact their service provider, Dandnaik said. So the MSO is trying to make it easy for customers by creating a database that collates touch points including chat, calls and the company's smartphone app so that if and when a customer calls in, all those contact points and information gleaned from them is readily available to an agent. Customers don't have to explain their issue again and the agent has all the information at his or her finger tips, which helps resolve the problem quicker and more effectively, Dandnaik said.
Companies like Nexidia and Amdocs have created software that allows operators to track customers' interactions and then present solutions. Amdocs is working with an unnamed multichannelvideo service provider to launch a project that will initially use big-data techniques to pinpoint variances in customers' billing and call history in an effort to head off future calls, as well as downgrades or disconnects.
For instance, if a good customer suddenly pays a bill late after consistently paying on time, the operator could reach out with a pitch for an autopay program, Yossi Zohar, marketing director of Amdocs' customer management division, said. The proactive-care program being deployed by the unnamed operator is designed to examine the last 12 months of the subscriber's payment history. It then determines if the customer has called the provider over that year, and instructs CSRs to notify the subscriber of any bill variances before he or she calls in. Research has shown that proactively reaching out to customers in this way will deflect ire and improve satisfaction and loyalty.
Because millions of potential combinations of independent variables can affect a dependent variable, prioritization is important, Pellet said. The proactive software can be programmed to detemine which action is required to resolve an issue. Often, resolving matters is as simple as calling a customer before the customer phones the call center. Sometimes, resolution comes in the form of a credit or a service call to a customer's home before a problem is noticed, he said. And customer-service agents could be given an early heads-up on issues customers might be calling about before those calls start to come in.
As in-home equipment has advanced, Mediacom is increasingly monitoring those boxes and will send customers new units (even if it doesn't receive a call from a customer) if the company notices repeated problems, Dandnaik said. In other cases, proactive care can mean contacting customers whose promitions are ending and putting them on a stepped-up plan that will soften the blow of a price increase, Dandnaik said. That kind of proactive contact has reduced Mediacom's churn and increased customer satisfaction in recent years.
Taking care of a system's network's reliability is probably the most effective form of proactive care out there, according to Bruce Leichtman, president of Leichtman Research Group. Cable operators have long been monitoring networks and nodes and notifying customers about service issues. He sees the best proactive care as taking care of the network and the system so customers don't have to call in for any reason.
"If a customer calls in to their system they want the problem resolved," he said. "The most important thing to them is that system works."
K.C. Neel


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Governor urges lawmakers to end 'unnecessary' budget impasse
In a public address less than 24 hours before the extra session opens, Rauner said he would sign into law the plan introduced by House and Senate Republicans just last week that would require more than $5 billion in tax increases to pay for spending capped at $36 billion. [Full Article...]
Arrested After Body of Newborn Is Discovered in Bag on Worcester Property
Worcester Police believe that Rheaume was pregnant, possibly with Santiago's child, and gave birth before tossing the newborn baby in a garbage bag. After a brief investigation, police determined that the bag had been moved and was now behind another home at 384 Lake Ave. [Full Article...]
12 cities to receive Justice Department aid to fight crime
Buffalo was the only city chosen in NY. Kansas City police announced Monday they plan to reassign officers from various units to patrol and target high crime areas in four small, geographic locations throughout the city. To the notoriously violent El Salvadorian gang MS-13, Sessions said in April: "We are coming after you". Drive-by shootings are up 51 percent from previous year. [Full Article...]
Spicer expected to take less public role
David Martosko - the USA political editor of DailyMail.com, who during the campaign earned a reputation for flattering coverage of Trump , with whom he had a personal relationship - also recently spoke to West Wing officials about the communications operation but is not expected to be offered a role, a senior administration official said. [Full Article...]
Amid public outcry, Florida city moves Confederate statute
The statue is being moved from Lake Eola Park to Greenwood Cemetery. This is not the first time the statue has been moved, as it was originally located on Magnolia Avenue before being moved to Lake Eola Park in 1917. It is unclear what is inside or when the city may open the time capsule. The City of Orlando is moving "Johnny Reb" from a park to a cemetery. Some, like New Orleans, have made ... [Full Article...]
Allegiant Adds Two New Destinations At CVG
Brian O'Neill, the airport's executive director and CEO said in the release. "This latest addition to the lineup further enhances our reach into the Western United States", he says. With those additions, Allegiant will offer service to 39 cities from Punta Gorda. The flight to Phoenix-Mesa Gateway Airport will begin October 4 and is seasonal. [Full Article...]
Republican aligned with Trump wins South Carolina House seat
The South Carolina 5th Congressional District Special Election has always been a long shot for Democrats , especially as Democrat Archie Parnell was unable to gin up as much national attention as Jon Ossoff, the Democratic candidate for Georgia's 6th Congressional District. [Full Article...]
Cheering 1st day of summer? Not in Phoenix when 120 expected
A scorching heat wave in Phoenix is expected to cause American Airlines to cancel 50 flights in the Arizona city. Las Vegas was forecast to hit 117F (47.2C) on Tuesday and excessive heat warnings cover nearly all of California. It comes as researchers say deadly heat waves like this one are going to grow more frequent. The heat also meant seven regional flights were delayed. [Full Article...]


NOTE *1 ARC compatible TV is required.
NOTE *2 App is available on the App Store. App is available on Google Play™.
TRADEMARK NOTICE Dolby and the double-D symbol are registered trademarks of Dolby Laboratories./DTS, DTS-HD, the Symbol & DTS and the Symbol together are registered trademarks, and DTS-HD Master Audio is a trademark of DTS, Inc./The Bluetooth® word mark and logos are owned by the Bluetooth SIG, Inc. and any use of such marks by Panasonic Corporation is under license. Other trademarks and trade names are those of their respective owners./Apple and the Apple logo are trademarks of Apple Inc., registered in the U.S. and other countries. App Store is a service mark of Apple Inc./"Google Play" and "Android" are trademarks of Google Inc./aptX® software is copyright CSR plc or its group companies. All rights reserved. The aptX® mark and the aptX logo are trademarks of CSR plc or one of its group companies and may be registered in one or more jurisdictions./HDMI, the HDMI Logo, and High-Definition Multimedia Interface are trademarks or registered trademarks of HDMI Licensing LLC in the United States and other countries.


Civil infrastructure is at the very heart of modern society. Be it for power, water, transport or healthcare; these technical systems are ubiquitously responsible for supervision, control, and management of infrastructure that lays the foundation for almost everything we do. Civil infrastructure provides essential services and shelter, it supports social interactions and drives economic development.
The importance of civil infrastructure makes system reliability paramount. However, as we modernize our aging infrastructure to add features for rapidly evolving technology, within our dynamic urban spaces, it can be challenging to design and build for the longer term. That's what the establishment of the Civil Infrastructure Platform (CIP) Initiative, hosted by the Linux Foundation hopes to address through open collaboration.
While much of the world's legacy infrastructure is aging, and not capable of supporting the growth of the population alongside a more sustainable environment, members of The Linux Foundation's Civil Infrastructure Platform (CIP) are working hand-in-glove to develop the software building blocks that will build smarter and smarter infrastructure powering smart cities (and more).


We Can Install Your Roof Right Away.
When it's that time to get a new roof or replace an old one, it is always a little overwhelming for anyone. Nobody wants to have to replace their roof, but when you do, you can count on OnePro Roofing to get it done the right way and as easy on you as possible. Our roofing contractors are some of the best around and will be able to guide you through the process very easily. We can even help you if you need to use insurance because we have done this many times before and know what insurance companies are looking for.
A roof installation can be done pretty quickly and with very little downtime. As long as the weather is right, our roofing team can get it finished within a day or two depending on the size of the roof and the kind of material you are getting. Regular roof installation is more straightforward because that usually means there isn't a roof on your home yet. This is when it has either been ripped off already or you have a new home that will be getting a roof for the first time. When we do a replacement, we have to take the old roof off and then install a new one. When we do this, we take the old roof off and then look at everything to make sure that it is all up to par with our high standards before we put the new roof onto your home. When you need to have a roof replacement done in Winter Park, FL, give us a call at (321) 354-1600 and we will be more than happy to get the job done for you.
If you notice any of these signs, give us a call at (321) 354-1600 and we will be able to have them repaired or replaced for you right away.
Asphalt Shingle Roofs Are a Top Quality Roofing Material.
Asphalt shingles come in two different types, fiberglass or organic. Each is very similar but do different things. Fiberglass shingles are great for fire protection, as they are coated with a protective coating that makes them waterproof. Organic, on the other hand, are made from paper and then coated to make them waterproof as well. These shingles have a lot of great qualities like being easy to install onto your roof, last for a long time, and come in a large variety of colors.
Just like with anything else, they do have a few cons that you should know about like not being able to install in very cold weather and that they do require maintenance to be done on them to keep them lasting as long as they are supposed to. This is very common with most roofing materials though so overall, this product is a great option to choose. The great part about asphalt shingles is that they are one of the most inexpensive roofing materials to choose from. They also come in many colors so that you can match them to your home in any way that you would like. There have been a lot of advances with asphalt shingles and can now even be gotten in architectural shingles which will add texture to your roof and has become a widely popular choice across residential homes. If you want more information about asphalt shingles, call one of our professionals at (321) 354-1600 and we will be happy to give you your options.
Roof inspections are one of the most important things that you can do for your roof as a home or business owner. When your roof is installed, the material is suggested to last for a certain amount of time. The way for the material to really last that long is to take care of your roof. The best way to do that is to have a roof inspection done once a year. The reason we suggest that is because once you have your roof inspected, it is likely that it will remain good for a full year. Many things can change within a year because the weather is unpredictable and you can't be sure that your roof will not become damaged.
Once your inspection is done, you will be able to see if any repairs need to be done or if it might be time to start considering a roof replacement. This is also a great opportunity for you to ask questions about your roof and get pricing quotes if you need them. A roof inspection checks the entire roof including your gutter system if you have them. They look for damage, mold, any kind of cracking or lifting of the shingles, and the overall quality of your roof. If you would like to have your roof inspected and want to know what the price will be, give us a call at (321) 354-1600 and we will be able to tell you and get you scheduled as soon as possible.
Our Professional Roofers Are Able To Get Your Roof Done Right Away.
When you need a roof replacement, it can be a little overwhelming to think about all that goes into that process. The good news is that we make it very easy for you and try to take all the stress of getting a new roof, away from you. A lot of times a roof replacement will come on the tail of a big storm. If you are going through your insurance, we can help you with that as well. We have been doing this for a long time so we know what the insurance companies are looking for.
Once we check out your roof, we can give you a quote and begin upon your approval. When you need a roof replacement, you should prepare by figuring out what kind of roofing material you would like and if you ever have questions you can give us a call at (321) 354-1600 and talk to one of our professionals about the different options and let us work with your budget to find you the best roof that works for you.
Updated on February 28, 2019 at 5:42 pm by OnePro Roofing.


Additional Info: Includes preface by Sandra Tanner.
Photo reprint of the 1825 edition that is believed to have influenced Joseph Smith during his creation of the Book of Mormon. Also contains the parallels between View of the Hebrews and the Book of Mormon by Mormon historian B. H. Roberts.


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Career Planning is a developmental process subsequently leading to a successful job search and placement. As part of the education experience, placement services are available during the entire period of a student academic involvement and after graduation, if needed. Optimum placement of the student in employment or higher education is the prime objective of the career-planning process.
The Career Center offers self-awareness development which involves sharing of information and examination of values, interests, and aptitudes as these relate to career planning.
The Center provides assistance with career exploration through in-depth investigation of selected careers. Decision-making involves clarifying goals, processing information, projecting for the future, and arriving at sound vocational decisions. Career planning and placement includes examination of education and training, job-seeking skills, and lifework planning. Portfolios are facilitated and available to be forwarded to prospective employers. Students are provided an opportunity to evaluate their career choices through the services provided in the Career Center.
Mrs. Holman-Brooks CDF, MA, M.Ed.


Designed to be bolted to the floor or welded to steel cross members.
Part # Model Finish Max Capacity Wt.
This lashing ring thickness has a diameter of 7/16". Mounting holes accept 3/8" bolts.
This lashing ring thickness has a diameter of 7/16".
This lashing ring requires a 3" diameter mounting hole in 1/4" material or thicker.


text:
Q: Jackson: (de)serialising Map with arbitrary non-string key I have a Scala Map keyed by a type that itself needs serialising to JSON. Because of the nature of JSON that requires key names for objects to be strings, a simple mapping is not directly possible.
The work around I wish to implement is to convert the Map to a Set before serialising to JSON, and then from a Set back to a Map after deserialising.
I am aware of other methods using key serialisers on specific types, e.g. Serialising Map with Jackson, however, I require a solution that applies to arbitrary key types and in this regard, conversion to Set and back again looks to me like the best option.
I've had some success serialising to a Set with a wrapper object by modifying MapSerializerModule.scala from jackson-module-scala below, but I'm not familiar enough with the Jackson internals to get that JSON to deserialise back into the Map I started with.
I should add that I control both the serialisation and deserialisation side, so what the JSON looks like is not significant.
case class Wrapper[K, V](
  value: Set[(K, V)]
)

class MapConverter[K, V](inputType: JavaType, config: SerializationConfig)
  extends StdConverter[Map[K, V], Wrapper[K, V]] {
  def convert(value: Map[K, V]): Wrapper[K, V] = {
    val set = value.toSet
    Wrapper(set)
  }

  override def getInputType(factory: TypeFactory) = inputType

  override def getOutputType(factory: TypeFactory) =
    factory.constructReferenceType(classOf[Wrapper[_, _]], inputType.getContentType)
      .withTypeHandler(inputType.getTypeHandler)
      .withValueHandler(inputType.getValueHandler)
}

object MapSerializerResolver extends Serializers.Base {

  val MAP = classOf[Map[_, _]]

  override def findMapLikeSerializer(
    config: SerializationConfig,
    typ: MapLikeType,
    beanDesc: BeanDescription,
    keySerializer: JsonSerializer[AnyRef],
    elementTypeSerializer: TypeSerializer,
    elementValueSerializer: JsonSerializer[AnyRef]): JsonSerializer[_] = {

    val rawClass = typ.getRawClass

    if (!MAP.isAssignableFrom(rawClass)) null
    else new StdDelegatingSerializer(new MapConverter(typ, config))
  }
}

object Main {
  def main(args: Array[String]): Unit = {
    val objMap = Map(
      new Key("k1", "k2") -> "k1k2",
      new Key("k2", "k3") -> "k2k3")

    val om = new ObjectMapper()
    om.registerModule(DefaultScalaModule)
    om.registerModule(ConverterModule)

    val res = om.writeValueAsString(objMap)
    println(res)
  }
}

A: I managed to find the solution:
case class MapWrapper[K, V](
  wrappedMap: Set[MapEntry[K, V]]
)

case class MapEntry[K, V](
  key: K,
  value: V
)

object MapConverter extends SimpleModule {
  addSerializer(classOf[Map[_, _]], new StdDelegatingSerializer(new StdConverter[Map[_, _], MapWrapper[_, _]] {
    def convert(inMap: Map[_, _]): MapWrapper[_, _] = MapWrapper(inMap map { case (k, v) => MapEntry(k, v) } toSet)
  }))

  addDeserializer(classOf[Map[_, _]], new StdDelegatingDeserializer(new StdConverter[MapWrapper[_, _], Map[_, _]] {
    def convert(mapWrapper: MapWrapper[_, _]): Map[_, _] = mapWrapper.wrappedMap map { case MapEntry(k, v) => (k, v) } toMap
  }))
}

class MapKey(
  val k1: String,
  val k2: String
) {
  override def toString: String = s"MapKey($k1, $k2) (str)"
}

object Main {
  def main(args: Array[String]): Unit = {
    val objMap = Map(
      new MapKey("k1", "k2") -> "k1k2",
      new MapKey("k2", "k3") -> "k2k3")

    val om = setupObjectMapper

    val jsonMap = om.writeValueAsString(objMap)

    val deserMap = om.readValue(jsonMap, classOf[Map[_, _]])
  }

  private def setupObjectMapper = {
    val typeResolverBuilder =
      new DefaultTypeResolverBuilder(ObjectMapper.DefaultTyping.NON_FINAL) {
        init(JsonTypeInfo.Id.CLASS, null)
        inclusion(JsonTypeInfo.As.WRAPPER_OBJECT)
        typeProperty("@CLASS")

        override def useForType(t: JavaType): Boolean = !t.isContainerType && super.useForType(t)
      }

    val om = new ObjectMapper()
    om.registerModule(DefaultScalaModule)
    om.registerModule(MapConverter)
    om.setDefaultTyping(typeResolverBuilder)

    om
  }
}

Interestingly, if the key type is a case class, the MapConverter is not necessary since the case class can be reconstituted from the string representation.

A: In my case, I had a nested Map. This required a small addition to the conversion back into a map:
addDeserializer(classOf[Map[_, _]], new StdDelegatingDeserializer(new StdConverter[MapWrapper[_, _], Map[_, _]] {
  def convert(mapWrapper: MapWrapper[_, _]): Map[_, _] = {
    mapWrapper.wrappedMap.map { case MapEntry(k, v) => {
      v match {
        case wm: MapWrapper[_, _] => (k, convert(wm))
        case _ => (k, v)
      }
    }}.toMap
  }
}))

redpajama_set_name: RedPajamaStackExchange


How was your weekend? Guess what I did? SWATCHING! And the first swatches I'm going to share with you are my A-England "Saint George" and "Dragon".
← Nail Files Bare All Challenge… Naked Nails, Whaaaat?!
Oh my god, I neeeeeed them!!


text:
Biła – dzielnica Szczyrku w formie ulicówki, położona w północnej części miasta, w dolinie potoku Biła, pomiędzy masywami górskimi Beskidka, Klimczoka i Magury.

Dawniej samodzielna wieś w gminie Szczyrk. 20 lipca 1953 otrzymała status samodzielnej gromady w gminie Szczyrk. 5 października 1954 włączona wraz ze Szczyrkiem Dolnym i Górnym do nowo utworzonej gromady Szczyrk. W związku z nadaniem gromadzie Szczyrk statusu osiedla 1 stycznia 1956, stała się jego integralną częścią, a po otrzymaniu przez Szczyrk praw miejskich 1 stycznia 1973 – obszarem miejskim.

Atrakcje turystyczne
 pozostałości po kompleksie skoczni narciarskich Biła
 skocznia narciarska Antoś
 naturalny tor saneczkowy
 wyciągi narciarskie na zboczach Beskidka
 schronisko THF "Chata Wuja Toma" na przełęczy Karkoszczonka
 punkt widokowy na Przełęczy Karkoszczonka.

Szlaki turystyczne
  – do Schroniska na Klimczoku przez Sanktuarium "Na Górce" – 1 godz. 55 min.
  – do Schroniska na Klimczoku – 2 godz. 20 min.
  – do Brennej przez Przełęcz Karkoszczonkę – 1 godz. 10 min.

Przypisy

Geografia Szczyrku

redpajama_set_name: RedPajamaWikipedia


Story time for children 18 months to 3 years old. Story Times consist of age appropriate storytelling, creative dramatics, music, movement and a craft. They are a wonderful way to encourage early literacy, a love of books and the library, as well as help prepare children socially for pre-school/kindergarten.
The Sign Language classes are informal, fun and educational experiences for birth to two year olds and their families. The programs focus primarily on rhymes and songs and learning of common sign language words and phrases. Registration is not required for these programs.
Kid-Fit is a fun physical fitness class for 3 to 6 year olds. Children must wear sneakers, comfortable clothing and should bring a filled water bottle.
Story Time for infants to 18 month old babies. Baby Time consists of age appropriate storytelling, music and movement. It is a wonderful way to encourage early literacy, a love of books and the library from infancy.
Story time for children 2 to 5 years old and their families. Story Times consist of age appropriate storytelling, creative dramatics, music, movement and a craft. They are a wonderful way to encourage early literacy, a love of books and the library, as well as help prepare children socially for pre-school/kindergarten.
Story time for children 3 to 5 years old. Story Times consist of age appropriate storytelling, creative dramatics, music, movement and a craft. They are a wonderful way to encourage early literacy, a love of books and the library, as well as help prepare children socially for pre-school/kindergarten.
Schedule a free one-on one appointment to receive training help with your device. Thirty minute sessions available by appointment. Call 772-226-3080 for more information or to schedule an appointment.
Time to get creative and MESSY! This hands-on program for two to five year olds will feature various media including painting, stamps, clay and more. Registration is not required, but children should wear clothes that can get dirty.
First Thursday of the Month join us for a cup of coffee and BINGO! Small prizes awarded to the winners.
March 18th: Principle 5: attract wildlife.
Every Tuesday beginning in July! Each session has a theme, but all tools will be available for use.
We provide the tools, you provide the creativity. All ages are welcome and it is free and open to the public. Registration is not required. More sessions will be added soon!
Fabric and yarn will also be available for use.
Take a break from test prep to make your own lucky charms out of polymer clay. All supplies provided! Teens only (grades 7-12).
A Mommy & Me event for those who want to learn more about Child Wearing.
Infants through 6 year olds are welcome to join in the songs and stories as we learn the art of child wearing. Little ones are encouraged to bring their own dolls to learn how to "wear" their babies, too.
Learn the 9 Principles of Florida Friendly Landscaping and other exciting gardening topics. Free and open to the public.
October 26th: Snowbird Gardening: Intro to Florida, plant selection, and plant establishment.
November 9th: Snowbird Gardening: Watering, pest management, and fertilizer.
December 14th: Snowbird Gardening: Lawn management and container gardens.
January 11th: Principle 1: Introduction to FFL and right plant, right place.
January 25th: Principles 2 and 4: Water efficiently and mulch.
February 8th: Principles 3 and 6: Fertilize appropriately and manage yard pests.
On May 11, from 10:30 a.m. to 1:30 p.m. families can take a Deep Dive Into the Lagoon through Literacy during a free, event at the Indian River County Main Library. The Moonshot Community Action Network (MCAN) brings together literacy, the arts, and environmental stewardship to shine a spotlight on the importance of literacy and the unique vibrancy of the community.
Immerse yourself in lagoon literacy with local environmental organizations during an afternoon of interactive, hands-on activities promoting the preservation of the Indian River Lagoon.
Fun, environmental education literacy activities will feature Mermaid Meg and the Magic Lagoon a book written by local author, Leslie Maloney. Additional activities include story time, prizes, photos with the East Coast Florida Mermaid and more.
Attendees are also invited to grab a paintbrush and apply their artistic talents to the Moonshot Mural. Artist Pam Sommers designed the collaborative arts literacy project using artwork created by children attending Moonshot afterschool programs.
The event will help to showcase the work of community partners aligned with the Moonshot Moment goal of 90 percent literacy by third grade and highlight the many ways we can care for our local ecosystem.
"This collaborative effort will be a powerful example of how we can spark our community into action," adds Arseneaux.
October 23rd: Snowbird Gardening: Intro to Florida, plant selection, and plant establishment.
November 13th: Snowbird Gardening: Watering, pest management, and fertilizer.
December 11th: Principle 1- Introduction to FFL and right plant, right place.
January 8th: Principles 2 and 4: Water efficiently and mulch.
January 22nd: Principles 3 and 6: Fertilize appropriately and manage yard pests.
February 12th: Principle 5: Attract wildlife.
The Spotlight Lecture Series provides monthly lectures on a variety of topics.
Did you know 1 in 5 adults struggle with Literacy? You can make a difference, become a volunteer tutor! Help someone learn to read or learn English.
When: 2 to 3 hours per week, you choose the day and time.
Where: Tutoring is always in a public facility.
How: Attend a free training workshop to become a volunteer tutor.
Join us to learn more about these stately trees and the essentials of pruning.
Presented by Katherine Booth from the City of Vero Beach Tree and Beautification Commission.
Join us for an afternoon of playing classic board games and card games. Scrabble, Quiddler, Chess, Checkers, and more! No registration required. This program is for adults.
Club meets the last Thursday of the month. 3:00 – 5:00 PM Book selections are available at the Library!


Comic book writer and artist Hilary Barta began his career in 1982, assisting Marvel inkers Al Milgrom, Joe Sinnott and Sal Trapani. Throughout the 1980s he worked only as an inker for both Marvel, First Comics and Eclipse. His credits include titles like 'The Thing', 'Starslayer', 'Warp', 'American Flagg', 'Power Pack' and 'Airboy'. As a penciller, he drew back-ups for Steve Rude's 'Nexus', and on stories for Marvel's 'What The--?!' and DC's 'Plastic Man'.
In the 1990s he was still doing mainly inking duties, among others on 'Alpha Flight', 'Power Pack', 'The New Mutants' and 'StormWatch'. He contributed stories to the Paradox Press 'Big Book' series and to Dark Horse's 'Urban Legends'. In 2000 he drew 'Splash Brannigan' stories for Alan Moore's anthology 'Tomorrow Stories'. Later on, he illustrated short stories for 'Simpsons Comics' and 'Treehouse of Horror' for Bongo Comics, 'Jimmy Neutron' stories for Nickelodeon Magazine, and 'Teenage Mutant Ninja Turtles' stories for both Mirage Comics and Titan Magazines.


text:
Chemistry; Biosynthesis
Novel Antimalarial Compounds Isolated in a Survey of Self-Medicative Behavior of Wild Chimpanzees in Uganda
Sabrina Krief, Marie-Thérèse Martin, Philippe Grellier, John Kasenene, Thierry Sévenet
Sabrina Krief
Institut de Chimie des Substances Naturelles, Centre National de la Recherche Scientifique, 91198 Gif-sur-Yvette Cedex
Marie-Thérèse Martin
Philippe Grellier
USM 0504, Biologie Fonctionnelle des Protozoaires, Muséum National d'Histoire Naturelle, 75231 Paris Cedex 05, France
John Kasenene
Makerere University, Biological Field Station, Fort Portal, Uganda
Thierry Sévenet
For correspondence: sevenet@icsn.cnrs-gif.fr
DOI: 10.1128/AAC.48.8.3196-3199.2004
Following a veterinary and behavioral survey of chimpanzees from a natural population in Uganda, leaf samples of Trichilia rubescens were collected because of the unusual method of ingestion observed. The methanolic crude extract of T. rubescens leaves exhibited significant antimalarial activity in vitro. Bioassay-directed fractionation provided two new limonoids, trichirubines A and B. A greater understanding of the role of secondary compounds in the primate diet may be helpful in recovering naturally occurring compounds of medicinal significance for human medicine.
Plant parts which have no apparent nutritive value and/or are rich in secondary compounds are ingested by chimpanzees (10, 14, 21, 22). Medicinal benefits of such ingestion have been suggested (8, 9, 20) by the observations of two unusual behaviors proposed to control intestinal parasite infection, namely swallowing whole bristly leaves and chewing the bitter pith of Vernonia amygdalina (7, 8, 18, 19). There is no chemical evidence to suggest a role of secondary compounds correlated with the leaf-swallowing behavior: more likely there is a mechanical effect of the surface of the whole rough hispid leaves leading to the expulsion of parasites. Instead of a physical effect, the benefit of bitter pith chewing is pharmacologically based on the activity of steroid glucosides (10, 14). In order to provide new information about self-medicative behavior of chimpanzees (Pan troglodytes schweinfurthii) and the phytochemistry of the plants ingested, field studies were conducted in Kanyawara, Kibale National Park, Uganda. The survey included behavioral data collection, as well as fecal and urine analysis of samples coming from identified chimpanzees. Particular attention was focused on sick individuals and unusual or occasional feeding behaviors. We report herein the bioassay-directed fractionation of the crude extracts of the plant leaves of Trichilia rubescens and elucidation of the structure of two limonoids, namely trichirubines A and B, which possess a significant anti-Plasmodium activity.
The study was conducted in the Kibale National Park (766 km2 between 0°13 to 0°41′N and 30°19′ to 30°22′E) in western Uganda. Data were collected between December 2000 and March 2001 (dry season) and in October 2001 (rainy season). The area contains mid-altitude moist forest, secondary forest, grassland, swamps, and plantations of Eucalyptus and pines, and it includes elements of lowland tropical rainforest, montane rainforest, and mixed deciduous rainforest. The elevation is between 800 and 1,500 m, and the rainfall averages 1,700 mm per year.
The Kanyawara community of wild chimpanzees (P. troglodytes schweinfurthii), including about 50 individuals, was observed. Feeding behaviors were recorded by 10-min focal-animal sessions and ad libitum observations (1). Health state was monitored daily by noninvasive methods consisting of clinical observations, coprological study of 252 stool samples, and urinalysis of 76 samples. We focused our behavioral observations on ill chimpanzees and unusual feeding behaviors, as plants eaten regularly and in large amounts probably did not contain highly active secondary compounds. Eighty-four crude extracts were made from the different parts of 24 plant species belonging to 13 botanical families. The crude extracts were evaluated for their antimalarial activities. After the first screening, plants exhibiting significant activities were submitted to chemical study in order to isolate the compounds responsible for bioactivities.
Air-dried powdered leaves (3 kg) of T. rubescens were macerated in heptane and then in methanol at 40°C. Filtration and vacuum concentration led to a dark-greenish extract (310 g).
Antimalarial activity was evaluated against intraerythrocytic asexual forms of Plasmodium falciparum. The chloroquine-resistant strain FcB1 of P. falciparum (50% inhibitory concentration [IC50] of chloroquine = 62 ng/ml) was maintained continuously in culture on human erythrocytes as described by Trager and Jensen (17). In vitro antiplasmodial activity was determined by a modification of the semiautomated microdilution technique of Desjardins et al. (6). Stock solutions of test extracts or compounds were prepared in dimethyl sulfoxide (DMSO) at a 10-mg/ml concentration. Drug solutions were serially diluted with culture medium and introduced to asynchronous parasite cultures (0.5% parasitemia and 1% final hematocrit) on 96-well plates for 24 h at 37°C, prior to the addition of 0.5 μCi of [3H]hypoxanthine (1 to 5 Ci/mmol; Amersham, Les Ulis, France) per well for 24 h. The growth inhibition for each drug concentration was determined by comparison of the radioactivity incorporated into the treated culture with that in the control culture (without drug) maintained on the same plate. The IC50 was obtained from the drug concentration-response curve and the results were expressed as the mean determined from three independent experiments. The DMSO concentration never exceeded 0.1% and did not inhibit the parasite growth.
Column chromatography on Merck silica gel 60 (reference no. 7736) was used for isolation and purification. High-performance liquid chromatography (HPLC) was carried out with a Waters HPLC instrument equipped with a UV photodiode array detector on C18 Thermohypersil Kromasil 250- by 21-mm 5-μm column at a flow rate of 16 ml/min. 1H nuclear magnetic resonance (NMR) (600 MHz), 13C NMR (150 MHz), and two-dimensional NMR were recorded on Bruker DRX 600 spectrometer. Mass spectra in the electron impact (EI) mode were recorded on a Kratos MS 50 instrument. Liquid chromatography-mass spectrometry (LC-MS) analyses in electrospray ionization (ESI) were conducted on a Thermoquest LCQ Deca ion trap coupled with an HPLC Thermofinnigan chain, using a Hypurity-C18 150- by 4.6-mm, 5-μm column at a flow rate of 1 ml/mn.
Column chromatography on silica gel of 51 g of methanolic extract eluted with a gradient of heptane-ethyl acetate (8:2 to 2:8) (column chromatography 1 [CC1]) led to 14 fractions. Fraction 10 (800 mg) was passed through a silica gel column eluted by heptane-acetone (8:2 to 1:9) (CC2), yielding 12 fractions. Fraction 10′ (81 mg) was a pure compound 1. The other active fraction, 7′ (IC50 = 0.2 μg/ml) was then purified by HPLC (45:55 H2O-acetonitrile).
Among unusual behaviors, we have observed the occasional ingestion of T. rubescens leaves by Kanyawara chimpanzees. We recorded five cases of consumption of T. rubescens Oliv. (Meliaceae) during the course of 700 h of observation. T. rubescens leaves were 1 of the 46 items consumed by the Kanyawara chimpanzees. The chimpanzee diet was dominated by fruit (81% of the feeding time was spent in fruit eating), and although the diet varied from month to month, only four plant species were consumed for more than 10% of the feeding time over the study period. Seventy-five percent of the feeding time was concentrated on six species: five for fruits and one for leaves. Of the 19 species on which chimpanzees spent 0.5% or more of feeding time, T. rubescens leaves were not present. Whereas the groups included two to six chimpanzees, in each bout of observation only one individual from the party ingested a few leaves of T. rubescens (mean of 5 leaves/min) for a short time (mean, 4 min 10 s; range, 2 to 7 min), leaving the shrub before having eaten all the leaves. The individual consuming T. rubescens leaves was different in each case. The other chimpanzees from the party did not even try to feed on the shrub after the consumer left it. Moreover this plant generally grows in a cluster so that leaves would be available for several chimpanzees. These observations suggest that chimpanzees eating T. rubescens leaves may be individuals with temporarily different criteria of food choice from other individuals in their party in spite of any symptom detected by health monitoring.
The plant part ingested was collected according to these observations. The crude MeOH extract exhibited an IC50 at 12 μg/ml. Fraction 10 obtained from CC1 yielded higher activity against P. falciparum (Table 1). Submitted to CC2, fraction 10 led to a pure compound 1 (81 mg), named trichirubine A, with a significant antimalarial activity (IC50 = 0.3 μg/ml) (Fig. 1).
Trichirubine A 1 was obtained as a yellow amorphous solid, [α]D25 +44 (c 0.1, CHCl3). EI mass spectrometry (EIMS) and ESI-MS gave a molecular ion peak at m/z 452.2 corresponding to the molecular formula C26H28O7. NMR spectra were obtained in CD2Cl2, but epimerization induced a doubling of the signals (Table 2). The structure of compound 1 was first determined on the basis of heteronuclear multiple-bond correlations (HMBCs). The correlations of the methyls with α and β carbons led to the skeleton drawn in Fig. 2. The HMBCs of the carbonyl C-1 with H-2 and H-3 implied the presence of a ring C-1, C-2, C-3, C-4, C-5, and C-10. The correlations obtained from both correlated spectroscopy (H,H COSY) and HMBC spectra prove the cycles B, C, and D. The lactone group was determined as located at C-17 on the HMBC correlations (H-17 to C-20, C-21 and C-22). Two epoxide groups were supported by very large coupling constants (JCH = 177 Hz and 184 Hz) observed for C-11 and C-15, respectively. The stereochemistry was determined by nuclear Overhauser effect (NOE) correlations.
Compound 2 (2 mg), named trichirubine B (Fig. 3), was isolated from the fraction 7′ (IC50 = 0.2 μg/ml). The small quantity isolated enabled us to determine the compound's structure, but the activity of the pure product after experiments including heating and acid addition could not be determined with certainty.
Trichirubine B 2 was obtained as a white amorphous solid. EIMS and ESI-MS gave a molecular ion peak at m/z 558.04 corresponding to the molecular formula C33H34O8. Because of the small quantity isolated, the 13C NMR spectrum could not be recorded. The 13C chemical shifts were determined by using the HMBC spectrum in which the doubling of signals was not observed due to the weak resolution in the carbon dimension. NMR spectra were also obtained in pyridine to confirm the determination of terpenic structure, while the spectrum in CD2Cl2 with trifluoroacetic acid (TFA) allowed lactone determination. Even with TFA, 1H signals were still broad and epimers were undistinguishable (Table 3). Compound 2 was related to compound 1, but Me-30, Me-18, and H-17 showed cross-correlation with a carbon at δ 151.37, suggesting that C-14 is an sp2 carbon. An additional phenyl group appeared in 1H NMR spectrum as well as an additional carbonyl (δ 167.50) linked to H-7 according to HMBC correlation. The structure of compound 2 has thus been assigned on the basis of this spectral data.
The genus Trichilia is known for its content in various limonoids, many of which are active against insects (4). In vitro antimalarial activities have recently been reported for limonoids from other Meliaceae: bark and seeds of Khaya grandifolia (2), bark of Khaya senegalensis (13), leaves of Azadirachta indica (11), and Cedrela odorata wood (3). The most active limonoid, gedunin, isolated from Khaya grandifolia, Cedrela odorata, and Azadirachta indica (3, 16), had a better in vitro activity than chloroquine against clones sensitive to chloroquine (15). Its in vitro activity evaluated against a chloroquine-resistant strain of P. falciparum (IC50 = 0.72 μg/ml) was roughly equivalent to that of trichirubine A (12), but its in vivo activity, initially poor (3), might be improved: for example, when combined with chloroquine (2), by synergism with dillapiol, a cytochrome P-450 3A4 inhibitor, or preparation of a more stable compound (16). Antimalarial activities may be related to the presence of reactive groups on ring A (4). As in the case of gedunin, the carbonyl group in C-3 and unsaturation in C-1/C-2 are currently observed in ring A of limonoids. The present structures of compounds 1 and 2 are original for two reasons: (i) the locations of these reactive groups, respectively, in C-1 and C-2/C3, as observed for limonoids isolated recently by deCarvalho et al. (5); and (ii) the presence of a lactone ring compared to the usual furan ring, as observed in limonoids and particularly in limonoids isolated by deCarvalho et al. (5). Those compounds also extracted from Trichilia rubescens leaves were shown to have potential activity in cystic fibrosis (5).
New evidence has been provided to support the previous hypothesis that chimpanzee diet contains secondary metabolites that may be useful to health maintenance. The study of self-medication in apes based in veterinary and behavioral survey might provide a novel approach to the discovery of new bioactive natural products useful in human therapy.
Trichirubine A 1.
HMBC correlations of trichirubine A 1.
Trichirubine B 2.
Antimalarial activities from CC1 and CC2a
1H (CD2Cl2, 600 MHz) and 13C (CD2Cl2, 150 MHz) NNMR data of trichirubine A 1
1H(CD2Cl2, 600 MHz) and 13C (CD2Cl2, 150 MHz) NMR data of trichirubine B 2
We acknowledge Richard Wrangham, codirector of the Kibale Chimpanzee Project, for valuable support in providing data and sharing experience and Claude-Marcel Hladik for important collaboration with the primatological survey. We are grateful to the Uganda Wildlife Authority and to the Uganda National Council for Science and Technology for permission to work in the Kibale National Park. For his kind and helpful collaboration in antimalarial screening, we thank Mehdi Labaied. For their valuable assistance with the fieldwork, S.K. expresses her sincere gratitude to the teams of K.C.P. and M.U.B.F.S. for their cooperation in the field.
Acknowledgments for funding are due to Centre National de la Recherche Scientifique and Museum National d'Histoire Naturelle, France.
We are indebted to the anonymous reviewers who provided interesting comments to improve the manuscript.
Received 19 December 2003.
Returned for modification 26 January 2004.
Accepted 5 April 2004.
Altmann, J. 1974. Observational study of behavior: sampling methods. Behaviour 48:1-41.
Bickii, J., N. Njifutie, J. Ayafor Foyere, L. K. Basco, and P. Ringwald. 2000. In vitro antimalarial activity of limonoids from Khaya grandifolia C.D.C. (Meliaceae). J. Ethnopharmacol. 69:27-33.
Bray, D. H., D. C. Warhurst, J. D. Connolly, M. J. O'Neill, and J. D. Phillipson. 1990. Plants as source of antimalarial drugs. Part 7. Activity of some species of Meliaceae plants and their constituent limonoids. Phytother. Res. 4:29-35.
Champagne, D. E., O. Koul, M. B. Isman, G. G. E. Scudder, and G. H. N. Towers. 1992. Biological activity of limonoids from Rutales. Phytochemistry 31:377-394.
DeCarvalho, A. C. V., C. P. Ndi, A. Tsopmo, P. Tane, J. Ayafor, J. D. Conolly, and J. L. Teem. 2002. A novel natural product compound enhances cAMP-regulated chloride conductance of cells expressing CFTRΔF508. Mol. Med. 8:75-87.
Desjardin, R. E., C.-J. Canfield, J. D. Haynes, and J. D. Chulay. 1979. Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique. Antimicrob. Agents Chemother. 16:710-718.
Huffman, M. A. 1997. Current evidence for self-medication in primates: a multidisciplinary perspective. Yearb. Phys. Anthropol. 40:171-200.
Huffman, M. A., and M. Seifu. 1989. Observations of illness and consumption of a possibly medicinal plant Vernonia amygdalina (Del.), by a wild chimpanzee in the Mahale Mountains National Park, Tanzania. Primates 30:51-63.
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Jisaka, M., H. Ohigashi, T. Takagaki, T. Nozaki, T. Tada, M. Hirota, R. Irie, M. A. Huffman, T. Nishida, M. Kajie, and K. Koshimizu. 1992. Bitter steroid glucosides, vernoniosides A1, A2 and A3, and related B1 from a possible medicinal plant, Vernonia amygdalina, used by wild chimpanzees. Tetrahedron 48:625-632.
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Antimicrobial Agents and Chemotherapy Jul 2004, 48 (8) 3196-3199; DOI: 10.1128/AAC.48.8.3196-3199.2004
You are going to email the following Novel Antimalarial Compounds Isolated in a Survey of Self-Medicative Behavior of Wild Chimpanzees in Uganda


X2C is a graceful professional pole fitness and Liquid Motion instructor who possesses a great feeling for music, and enjoys being able to express herself creatively through movement. She took her first class in 2008 with FiyaStarta Aka Torwa Joe and has been hooked ever since! She immediately enrolled in the series program, graduated the sensual and acrobatic track, then wondered where her pole career would go. Little did she know that FiyaStarta had plans for her. X2C attended her first PoleCon in Palm Beach with Vertical Joes and ended up assisting with instruction because of the overwhelming response to the first ever Booty Clap class. Upon arrival back to Atlanta, FiyaStarta asked when she was going to start teaching. X2C enrolled in the next certification class, and has been teaching ever since. She is over series and 1:1 instruction at Vertical Joe's, and currently has two of the hottest classes there. X2C is part of the Vertical Joe's performance team and teaches workshops at pole conventions.


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Florida Wild Turkey Cost-Share Program aiding habitat enhancement on public land
Through the Florida Wild Turkey Cost-Share Program, 385 acres of wildlife habitat were improved on the Little Big Econ State Forest, a 10,279-acre segment of public land in Seminole County, Florida.
The Florida Wild Turkey Cost-Share Program is a collaborative initiative between the NWTF, Florida Fish and Wildlife Conservation Commission and the Florida Forest Service that provides resources, funds and leveraging ability to complete wild turkey habitat enhancement projects on public lands throughout Florida.
Roller chopping, a wildlife management technique that minces dense brush and small diameter trees, was used to reduce thick saw palmetto and shrubs, primarily scrub oaks. This allows for more effective controlled burns in the future and reduces the risk of wildfire.
"The roller chopping and subsequent controlled burning will create early successional habitat that includes more grasses and forbs in the understory, providing better wild turkey habitat," explained David Nicholson, NWTF district biologist. "This project will not only improve habitat for wild turkeys, but it will also improve habitat for bobwhite quail, gopher tortoise, Southeastern American kestrel and other wildlife found in Florida.
"The Florida Wild Turkey Cost-Share Program was initiated in 1996 and since has improved significant amounts of habitat on public lands open to turkey hunting," Nicholson said. "During this year alone, the program includes 38 habitat projects on 29 WMAs and three focal areas. The program's total value is more than $1.9 million, and it is expected to enhance more than100,000 acres of turkey habitat. Additionally, this program allows the NWTF to leverage funds in working with 12 different land management agencies that also contribute funds and/or labor to the projects."


I'm obviously starting to lose my marbles. Quite clearly a full time job, motherhood, helping my husband run his business, being owned by two dogs, training for a half marathon and trying a new recipe every day - and blogging about it - is clearly taking its toll. Or maybe this is just the start of the slow slide into senility. After all, according to Ian Beale, you stop being young at 35. Someone shoot me now!
Last night I was mildly mortified to find out that someone had been eagle-eyed enough to spot a typo on my blog post. The lovely Sadia aka @bakingelements (find her blog here) tweeted me for my poor spelling of 'juice'. I leapt to my defence, wittering on that I was obviously influenced by the lovely Miss A's constant demands for 'owinge jice pwease Mama'. In fact, it was just sloppy, slovenly spelling. Something I abhor.
Don't get me started on txt spk. It drives me potty. I'd rather send three text messages than skip characters. I love Twitter, but honestly, the amount of time I waste agonising over which words and bits of punctuation to remove to hit the 140 character limit. I've even embarrassed my mother in a posh restaurant by getting a red felt tip out of my handbag (this was back when I was training to be an English teacher - I'm now an analyst, a very telling profession) and circling all the typos on the menu then writing something along the lines of 'B minus - could do better' before replacing it in the stack of menus that had been put on our table.
And to top yesterday off, hoping for a decent night's sleep and a lie in (if you can call staying in bed till 7am a lie in!), I woke in a panic at 11.45pm, thoroughly convinced it was Sunday night and I'd not left Miss A's clothes and other paraphernalia out for nursery. I then spent twenty minutes rushing round the house on tiptoe finding clothes, locating shoes, packing her lunchbox and trying not to yelp when I stood on random pieces of post-Christmas plastic detritus that got missed in the bedtime clearing up session. Returning to bed, I snuggled down, only to jolt awake twenty minutes later with the realisation that it was in fact still only Saturday morning.
Which brings me neatly on (okay it's a tenuous link!) to today's recipe. I'm made Thomasina Miers' Chilli Jam from Mexican Cooking Made Easy. The full recipe sees it served with lamb chops, but it sounded so amazing that I decided to make it to go with the Tiger Bread I'm going to make tomorrow. Cold cuts, cheese, chilli jam and fresh bread. Perfect after the seven mile run I have planned for the morning.
And here comes the tenuous link. I had to retake the picture of the ingredients seven times as I kept forgetting things on the recipe list. And it's not even that good a picture after all the reattempts. The photo-pro I live with would be horrified. If only he'd get me a kitchen built next to his studio, I'd have gorgeous pictures :o). And still I missed putting the sugar into the frame! Hey-ho.
I've mentioned before that I don't actually like tomatoes. There's just something fundamentally wrong in my eyes with the slimy bit in the middle, but I'm gradually learning to love them in other ways besides in a pasta sauce or courtesy of Heinz. I had an amazing semi-dried tomato and green bean salad at work the other day. Something I'd love to try to replicate one day. They even give me the creeps when the slimy stuff comes out when I have the misfortune to cut them up. And despite the copious amounts of tomatoes that went into this, the end result is well worth having to chop up pounds of the things.
This jam, like all of the recipes I've tried from this book, is amazing. I have a bit of a girl crush on Thomasina. Or at least her food. I'd love to live in her house and eat amazing food like this day after day. I tasted a bit on a cracker with a sliver of cheese and I was in absolute heaven. When I decanted it into the jar, I had to fend off Miss A who mistook it for real jam and actually ate something with vegetables in it. She didn't even mind the spicy kick. Much. I could've licked the pan clean - but restrained myself.
Really, you do have to try this. It is just so darned tasty. That said, I only had 900g of tomato thanks to Ocado but halved all the other ingredients, so I have a feeling the taste is a little more intense than it would've been had I been bothered to correctly scale it down. Maths is not my strong point.
I was intending to stop by Allington Farm Shop and buy some lamb cutlets to complete the recipe, but I'm not sure the jam will last that long once I get at the bread and cheese tomorrow. I got about 400g from my 900g of tomatoes. Initially I wasn't too bothered as I didn't want to be left with gallons of the stuff if I didn't like it. I'm now regretting this faux pas and considering growing my own tomatoes this summer just so I can make enough to bathe in. I like it that much. And on that subject, I really must create a page for things I'd make again. This is one of them - and surprisingly, number one so far!
You can find the recipe online here, but I do urge you to buy the book. It's RRP is £20 but it's on Amazon for £12.40 at the time of writing.
And do check back tomorrow when I will hopefully have a better picture of the finished jam accompanying some lovely Tiger Bread. Growl!


How to get Vietnam visa from Iraq?
Whoever living in Iraq has Iraq passport holder or other nationalities which are not in the Vietnam Visa exemption list that must have Visa to enter Vietnam.
Until now, The Embassy of Vietnam has not established in Iran. You have to apply for Visa to Vietnam in person at Vietnam Embassy near around your country.


John Mayer's "Continuum" album was incredibly popular, won a Grammy and got named the 11th best album of 2006 by the Rolling Stone magazine – and for a good reason. It's a fantastic album that mixes all its main ingredients well and uses exactly the right measurements: It's produced but features a real band playing real instruments; it's a soul record but yet, exhibits a pop sensitivity; the vocals are strong but not overly dramatic; and the arrangements are adventurous but simple enough for the record to resonate with the casual listener. And what is true for the album is also true for its opening track and most successful single "Waiting On The World To Change."
The bells, the organ, the swinging drums and the Memphis-style guitar licks make "Waiting On The World To Change" timeless music. In fact, when you are listening to both the song as well as its lyrics, your mind is fooled into thinking that you've just discovered a long-lost soul outtake from the late sixties or early seventies by Marvin Gaye.
However, putting more emphasis on his lyrics wasn't the only change Mayer made in terms of artistic direction when he began working on "Continuum." With this album Mayer was no longer satisfied being just a singer-songwriter. He decided to take on the role of co-producer as well – excellent choice. Another excellent choice was to enroll just the right guy as his collaborator in the studio, Steve Jordan. Jordan was known for his work with such legends as Keith Richards, Chuck Berry and Stevie Wonder – not surprising then that "Continuum" is a lot more blues and soul oriented album than Mayer's work preceding it. Having said that, it is John Mayer who shines throughout the album with his vocals, guitar playing and his songwriting skills. I dare say, everything on this album is so good that by the time you are listening to the amazing "Gravity," you are afraid to listen on, scared that the spell will break and the next song will bring the album down a peg or two; however, this never happens, the spell never breaks. Instead, it intensifies. In fact, the last song on the album, the Otis-Redding flavored "I'm Gonna Find Another You" is one its most brilliant cuts – not bad for a guy who was pumping gas at a filling station after high-school.
In addition, check out this very exciting live performance of the song.


As an Earthwatcher, you can make a difference whilst having fun, getting outdoors and meeting new people along the way.
Whatever your age, interests and abilities, we have a range of hands-on projects, fantastic events and fundraising opportunities for you.
Whether you nurture wildlife in your garden, monitor the water quality of your local river or help us to understand how climate change is affecting our coastline, your local actions will have a global impact and deliver science that matters.
Tackle environmental challenges by reconnecting with nature, taking hands-on action and improving our understanding of the issues.
Our events inform, connect and inspire. Come along and find out more about the issues that matter to the future of the planet.
Let the forest be your classroom with climate change education programmes for teachers and students.
Run, swim or cycle for a more sustainable planet.


Cane-line's new table Core combines the classic with the modern and lifts the use of teak in outdoor furniture to new levels. The soft curves of the table top are paired with a frame of conical pipes in powder coated aluminium. The result is a table that in spite of its light appearance is very strong and hardwearing.
The teak slats are hand-selected and of highest FSC certified teak. The Core tables come in three different sizes and two frame colours enabling you to find the right table for your needs.
Teak table tops are supplied untreated and will develop a patina over time.If you wish to treat your teak table top, we recommend using teak oil - this will makethe wood darker.
To ease spring cleaning you can store your teak table under a cover.


Saltwater Review: This Time Its Not A Sea, But A Cafe!
Leopold Cafe Mumbai Review: Serving Since 1871 !
Keventers Review: The Place For the Original Milkshake !
Food Review: Gluten and Special K Gluten Free Kellogg's Corn Flakes!
Punjab Grill Review: A Place For Punjabi Delicacies!
Kesariya Restaurant Review: For The Desi Food Lovers!
Malaka Spice Restro Review: A First Look Inside !
Bukhara Delhi, Review: The Perfect Place To Fulfill Your Appetite?
Barbeque Nation Review: How Is It Being There?
Global Fusion Review: The Home To Buffet Meals !
Shang Palace Delhi Review: A Foodie's Paradise?
Kayani Bakery Review: Leaving Behind A Legacy !
German Bakery Review: The Iconic Healthy Food Joint In Pune !
MainLand China Pune Review: A Restaurant Serving Authentic Chinese Food !
Nashik: Sadhana Restaurant,The Exclusive Food Outlet Serving "Misal"!
Cafe Good Luck- Visiting The Historical Irani Cafe !
Marz-O-Rin: Get To Know This Place That Serves Exclusive Bread Items!
Gustoso: The Place That Serves The Largest Pizza In Mumbai !
Burger, Pune: A Food Joint That Will Leave You Crave For More !


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HackSpace Magazine Issue 51: Tracking workshop…
"I Am Not Your Scapegoat": Artworks Denounce Increasing Anti-Asian Bigotry #ArtTuesday
In New York City alone xenophobic harassment towards Asian and Asian Americans has increased multiple times over. The public art project "I Still Believe in Our City" combines powerful images with real facts on discrimination and bias.
Via Hyperallergic:
Amanda Phingbodhipakkiya, the Publci Artist in Residence at the Human Rights Commission, addressed this concerning phenomenon with an ad takeover of the Atlantic Avenue subway station in Brooklyn. Titled "I Still Believe in Our City," the public art installation celebrates New York's diversity with a series of 45 panels featuring vibrantly colored portraits of Black, East Asian, and Southeast Asian residents of the city. These portraits are accompanied by anti-discriminatory messages like "I did not make you sick," "This is our home too," and "I am not your scapegoat."
"Despite being confronted with anti-Asian bias and rhetoric, Asian and Pacific Islander [API] New Yorkers continue to fight for our city, for our neighbors, and for justice," Malalis continued. "Amanda's art gives us something beautiful, moving and celebratory when we need it most and it encourages API New Yorkers to remain visible and proud."
Every Tuesday is Art Tuesday here at Adafruit! Today we celebrate artists and makers from around the world who are designing innovative and creative works using technology, science, electronics and more. You can start your own career as an artist today with Adafruit's conductive paints, art-related electronics kits, LEDs, wearables, 3D printers and more! Make your most imaginative designs come to life with our helpful tutorials from the Adafruit Learning System. And don't forget to check in every Art Tuesday for more artistic inspiration here on the Adafruit Blog!
Filed under: art, NYC —
Tags: art, Art Tuesday — by Ben
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"Only knowledge that is used sticks in your mind"


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Education Partner News
Education Program and Policy
Indigenous Education Updates
Ministry of Education Update
Ontario Newsroom
OPSBA Awards
OPSBA Events
OPSBA News
School Board News
Trustee PD
September 2021 - OPSBA
Honouring the first National Day for Truth and Reconciliation
2021 9/29 | Connects Page, Indigenous Education Updates, OPSBA NEWS, OPSBA News
September 30, 2021, marks the first National Day for Truth and Reconciliation. On this day, schools and school boards across Ontario, including students, staff, and school communities, will be commemorating the tragic history and ongoing legacy of residential schools, which more than 150,000 First Nations, Métis, and Inuit children were forced to attend between the 1870s and 1997.
OPSBA Board of Directors Meeting – September 25, 2021
The Ontario Public School Boards' Association (OPSBA) Board of Directors held a virtual meeting on Saturday, September 25, 2021. President Cathy Abraham gave an acknowledgement that participants in the meeting were connecting to the meeting from numerous traditional...
2021 9/27 | Connects Page, Education Finance, Education Policy, Federal Issues, Legislative Updates, Ontario Newsroom, OPSBA News
The Legislative Assembly of Ontario will resume in two weeks on Monday, October 4, 2021. House Speaker Ted Arnott has confirmed "everyone seeking to enter" the legislature will require either proof of vaccination or a recent negative COVID-19 test. The new rules will...
2021 9/20 | Connects Page, Education Policy, Elections, Federal Issues, Legislative Updates, Ontario Newsroom
The Legislative Assembly of Ontario will resume October 4, 2021. COVID-19 Update / Return to School Fall 2021 As of the morning of September 17, 632 cases of COVID-19 have been reported in publicly funded schools in the past 14 days. Of those cases, 526 are students,...
2021 9/13 | Connects Page, Education Finance, Education Policy, Education Program and Policy, Elections, Legislative Updates, Ontario Newsroom
As previously noted, the Legislative Assembly of Ontario will now remain adjourned until October 4, 2021. COVID-19 Update / Return to School Fall 2021 The COVID-19 cases in schools and child care centres webpage has been updated with a note stating that the page has...
2021 9/13 | Connects Page, Education Finance, Education Policy, Legislative Updates, Ontario Newsroom
On September 3, Government House Leader Paul Calandra issued a statement to the media about the decision to prorogue the legislature until October 4, 2021. Prorogation is the act of completely ending a session of Parliament, and has the effect of terminating all...
OPSBA in the Media – September 2021
2021 9/2 | Connects Page, OPSBA in the Media
What to know about our first National Day for Truth and ReconciliationThe London Free Press - Sep. 29, 2021Thursday marks Canada's first National Day for Truth and Reconciliation, a day to remember the more than 150,000 First Nations, Inuit and Métis children who were...


Former U.S. Rep. Melissa Hart has rejoined Pittsburgh law firm Keevican Weiss Bauerle & Hirsch LLC as a member.
Hart was defeated by Jason Altmire last November after serving three terms as the Republican representative from McCandless.
Keevican Weiss Bauerle & Hirsch launched in 1988 and has offices in Cleveland and Harrisburg. In 2003, the firm, then ranked as Pittsburgh's ninth largest and known as DKW Law Group PC, filed for protection from creditors under Chapter 11 of the federal bankruptcy code, emerging successfully later that year. It adopted the current name in early 2006.
Hart said in a statement that she was "happy to be back in a professional capacity at a first-rate organization among long-term friends and colleagues."


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What Is Considered A High News Score?
– A high score (NEW score of 7 or more) should prompt emergency assessment by a clinical team/critical care outreach team with critical-care competencies and usually transfer of the patient to a higher dependency care area.
What is an early warning score chart as implemented in all Irish hospitals?
An Early Warning Score (EWS) is a bedside score and track and trigger system which nursing staff calculate from the vital signs recorded, and aims to indicate early signs of a patient's deterioration.
What NEWS chart means?
An early warning score (EWS) is a guide used by medical services to quickly determine the degree of illness of a patient. It is based on the vital signs (respiratory rate, oxygen saturation, temperature, blood pressure, pulse/heart rate, AVPU response).
What is the NHS scoring system?
The system sees each patient given an overall score based on a number of vital signs such as heart rate, oxygen levels, blood pressure and level of consciousness. Doctors and nurses can then prioritise patients with the most urgent NEWS scores.
What is the highest NEWS score?
The total possible score ranges from 0 to 20. The higher the score the greater the clinical risk. Higher scores indicate the need for escalation, medical review and possible clinical intervention and more intensive monitoring (see table one).
What is a normal NEWS2 score?
The recommendation for a NEWS2 aggregate score of 0 (that is, no change to any parameter) is a minimum 12‑hourly review and to continue routine monitoring.
What is a NEWS2 chart NHS?
The National Early Warning Score (NEWS2) is a system for scoring the physiological measurements that are routinely recorded at the patient's bedside. Its purpose is to identify acutely ill patients, including those with sepsis, in hospitals in England.
How do you interpret NEWS scores?
What does a NEWS score of 6 mean?
Medium risk (aggregate score 5 to 6) – urgent review by ward-based doctor or acute team nurse to decide on escalation to critical care team. • High risk (aggregate score of 7 or over) – emergency assessment by critical care team, usually leading to patient transfer to higher-dependency care area.
What does NEWS score indicate?
NEWS is a tool developed by the Royal College of Physicians which improves the detection and response to clinical deterioration in adult patients and is a key element of patient safety and improving patient outcomes.
High risk (aggregate score of 7 or over) – emergency assessment by critical care team, usually leading to patient transfer to higher-dependency care area. The recommendation for a NEWS2 aggregate score of 0 (that is, no change to any parameter) is a minimum 12-hourly review and to continue routine monitoring.
How do you interpret NEWS2 scores?
A NEWS2 score of 5 or 6 is considered a key threshold that may indicate clinical deterioration and should prompt urgent response by a clinician or a team with competence in assessment and treatment of acutely ill patients [8]. The NEWS2 scoring chart is utilised as part of routine patient care practice at our hospital.
How many parameters are in the NEWS score?
The NEWS2 scoring system measures 6 physiological parameters: respiration rate. oxygen saturation. systolic blood pressure.
What are the benefits of using the NEWS2 tool?
What are the benefits of using NEWS2 in the community? NEWS2 can facilitate communication at the interfaces of care such as when requesting ambulance transfer or hospital assessment.
Respiratory rate.
Oxygen saturations.
Systolic blood pressure.
Pulse rate.
Level of consciousness.
What is a pew score?
Identifies pediatric patients at risk for clinical deterioration. Pediatric inpatients. Originally developed to provide a practical and objective method to identify pediatric inpatients at risk for cardiac arrest.
What is a normal Mews score?
Modified Early Warning Score (MEWS)
MEWS score
Type of score
The patient should remain under specialized care and assessed again in 2 to 8h.
The patient has an increased mortality risk and is highly likely to be moved to ICU or HDU.
What is the NEWS2 chart used for?
The technology. The National Early Warning Score (NEWS2) is a system for scoring the physiological measurements that are routinely recorded at the patient's bedside. Its purpose is to identify acutely ill patients, including those with sepsis, in hospitals in England.
What is SOFA score in sepsis?
The sequential organ failure assessment score (SOFA score), previously known as the sepsis-related organ failure assessment score, is used to track a person's status during the stay in an intensive care unit (ICU) to determine the extent of a person's organ function or rate of failure.
What is the scoring system for sepsis?
Called the quick SOFA (qSOFA) score, it includes 1 point for each of 3 criteria: (1) respiratory rate ≥ 22 breaths/min, (2) altered mental status, or (3) systolic blood pressure (SBP) ≤ 100 mm Hg. A qSOFA score ≥ 2 is suggestive of sepsis.
How do you calculate NEWS score?
NEWS uses six physiological measurements: respiratory rate; oxygen saturation; temperature; systolic blood pressure; heart rate and level of consciousness. Each scores 0–3 and individual scores are added together for an overall score. An additional two points are added if the patient is receiving oxygen therapy.
What does a mews score of 4 mean?
The sum of the scores of the six vital signs yields the patient's total MEWS score. If the total score is 4 or greater, this prompts the nurse to call the patient's physician and also the organization's outreach team.
What does NEWS mean in medical terms?
What Response Is Required By A News2 Score Of 5 In A Patient…
What Two News 2 Scores Can Trigger A Clinical Response?


assemblage - Sheffield Graduate Journal of Archaeology - Home. ... love most: serious scholarship and great extras! Contact us at. assemblage@sheffield.ac.uk.
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There is substantial heterogeneity in the clinical behavior of pancreatic cancer and in its response to therapy. Some of this variation may be due to differences in delivery of cytotoxic therapies between patients and within individual tumors. Indeed, in 12 patients with resectable pancreatic cancer, we previously demonstrated wide inter-patient variability in the delivery of gemcitabine as well as in the mass transport properties of tumors as measured by computed tomography (CT) scans. However, the variability of drug delivery and transport properties within pancreatic tumors is currently unknown. Here, we analyzed regional measurements of gemcitabine DNA incorporation in the tumors of the same 12 patients to understand the degree of intra-tumoral heterogeneity of drug delivery. We also developed a volumetric segmentation approach to measure mass transport properties from the CT scans of these patients and tested inter-observer agreement with this new methodology. Our results demonstrate significant heterogeneity of gemcitabine delivery within individual pancreatic tumors and across the patient cohort, with gemcitabine DNA incorporation in the inner portion of the tumors ranging from 38 to 74% of the total. Similarly, the CT-derived mass transport properties of the tumors had a high degree of heterogeneity, ranging from minimal difference to almost 200% difference between inner and outer portions of the tumor. Our quantitative method to derive transport properties from CT scans demonstrated less than 5% difference in gemcitabine prediction at the average CT-derived transport value across observers. These data illustrate significant inter-patient and intra-tumoral heterogeneity in the delivery of gemcitabine, and highlight how this variability can be reproducibly accounted for using principles of mass transport. With further validation as a biophysical marker, transport properties of tumors may be useful in patient selection for therapy and prediction of therapeutic outcome.