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Humboldt County is well-positioned in regards to transportation and logistics. With the intersection of US Highway 169 and State Highway 3 in Humboldt and the proximity to Interstate 35 and Interstate 90, Humboldt County offers tremendous access to major distribution areas across the Midwest.
US Highway 169 runs north and south and State Highway 3 runs west and east through Humboldt County. Humboldt County communities are approximately 30-45 minutes west of Interstate 35 and 15-30 minutes north of US Highway 20 and approximately 60 minutes south of Interstate 90.
Location Approximate
Distance in Miles Approximate
Minneapolis, MN 200 miles 3.25 hours
Chicago, IL 415 miles 7.75 hours
St. Louis, MO 453 miles 7 hours
Kansas City, MO 280 miles 4.25 hours
Des Moines, IA 113 miles 1.75 hours
Omaha, NE 177 miles 3 hours
Union Pacific Railroad has lines serving the following Humboldt County communities: Bode, Gilmore City, Hardy, Livermore, LuVerne, Ottosen and Pioneer. Additional information can be obtained by visiting Union Pacific Railroad's website.
The Humboldt Municipal Airport will accommodate single engine aircraft up to twin engine aircraft. The runway is 60 x 3417 and is 12/30. There is a 24-hour terminal with phone service. The Fort Dodge Regional Airport provides connecting flights to major airports and is located 15 miles south of Humboldt.
Low cost public transit bus service is provided for Humboldt County by Pathfinders Strategic Partners. For more information check out Pathfinders Facebook.
Humboldt County offers safe, reliable and dependable utility service to residents and businesses. From water and wastewater in each community to gas, electric and telecommunications provided through utility partners, Humboldt County is positioned for growth!
*Midland Power Cooperative *MidAmerican Energy Company
*MidAmerican Energy Company
(Click on the City you are needing information on)
City of Bode City of Bradgate
City of Dakota City City of Gilmore City
City of Humboldt City of Livermore
City of Ottosen
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For more information on transportation services in Humboldt County, please contact us.
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AtlWolf is a furry and fursuiter who lives in Norcross, Georgia, U.S.A. His fursuits are Emo. T. Wolf (purchased from Badwolf in 2010) and Salsa (purchased in 2012 from Wezen).
AtlWolf organizes furmeets in and around the Atlanta area. He also works as staff for Furry Weekend Atlanta Atl has also worked staff and hosted panels for many years, at fandom conventions such as DragonCon.


Need to tidy this place up and hide some of the more removals-men-scaring stuff.
Fairly clear plan ahead for move.
Go to The Link on Friday to sort the new phone out. And buy socks.
Contact Eurolet ASAP and cancel flat.
Set up Royal Mail redirects as soon as I get a new address.
Tell my wife I'm moving (and why the divorce ain't moving)!
Take small change to machine in Sainsbury.
London suddenly looks very close, this side of Whitby.
Will be great when you and Karen move to London. Much closer for much partying and shopping for pretty things.


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Grill 'n Chill is held once a month from April through September after the Monday night ride. It's a fun time to socialize and get a quick bite to eat before heading home. The LWA provides hot dogs, burgers, and non-alcoholic beverages. Members donate side dishes and desserts. You can also bring your lawn chair and your favorite beverage.
If you can't make the Monday night ride, or you are a non-cycling spouse/partner, you can still join us! Volunteers are always needed to cook on the grill or monitor the food tables.
• Bring donations to the food table before you ride! We have coolers available to keep everything cold.
• We provide serving utensils! If you want your container back, mark it with your name.
For more information, questions or to volunteer, contact our Grillmeister.


text:
Q: Send Text Msg to Mobile Number I am working on some website in which I fetch some user information from DB to webpage and I also have one textbox and one send msg button on this page. I want that when user puts any mobile number on the textbox and click send button then the text message should go on that Mobile number with some data i want to send.
Mail functionality is very easy to implement but I never user text msg kind of functionality.
Tell me in detail which server or port I have to use it and I want to send free unlimited text msgs like we send mails from Google server.
How to do it?

A: I doubt you will find anything completely free. Here are two services Ive personally used, I think AWS stuff is probably better but you will have to experiment:
AWS Simple Message Services (SNS)
and
Twilio

A: You Can use a GSM Modem(USB GSM Modem). it has AT Commands and you can easily send SMS to mobile phones.

redpajama_set_name: RedPajamaStackExchange


While Paris Hilton may have starred on "The Simple Life," she certainly was not living the simple life in real life. Her party girl lifestyle started when she was a teenager living at Waldorf Astoria in New York City. She started going to clubs with her sister, Nicky Hilton. In the early 2000s, Hilton was everywhere and her partying was crazier. She has been arrested for a DUI and spent 23 days in jail. Hilton continues to be scene at all the newest hot spots with her always changing current fling.
Bijou Phillips moved to New York to be a model in actress when she was only 14. As her modeling popularity increased, so did her partying. Before the age of 20, she became notorious for her wild behavior and was even sent to rehab. In the last few years Phillips has slowed down her partying ways, she got married in 2011 to Danny Masterson and the couple had a daughter in February 2014.
The Former BFF of Paris Hilton, Nicole Richie was always getting photographed partying all over NYC and Hollywood's hot spots. Richie started sneaking into clubs when she was only 14. After she turned 21, Richie was arrested and subsequently sent to rehab for getting caught with heroin in her car. Her first rehab stint didn't change her party girl ways. In 2006, she was arrested for driving the wrong way on a highway and admitted to taking drugs. Richie finally left her partying ways behind her and is now a business owner, mother to son, Sparrow James Madden and is married to Joel Madden.
One of Paris Hilton's posse of girls, Kimberly Stewart was big into the L.A. party scene. Daughter of musician Rod Stewart, Kimberly Stewart partied so hard that she developed a severe liver disease. Stewart has dated many other celebs and socialites including, Gerard Butler, Jack Osbourne and Jude Law. Stewart dated Benicio del Toro and the pair had a daughter together in 2011. Since becoming a single mother, Stewart has reformed her partying ways.
Britney Spears went from innocent girl next door to crazy party girl in an extremely short timespan. After her divorce from Kevin Federline, Spears began her bad girl downward spiral. After being spotted staying out all night and dancing on tables, Spears was admitted to multiple rehab facilities, shaved her hBritney Spears went from innocent girl next door to crazy party girl in an extremely short timespan. After her divorce from Kevin Federline, Spears began her bad girl downward spiral. After being spotted staying out all night and dancing on tables, Spears was admitted to multiple rehab facilities, shaved her head and eventually lost custody of her kids. Spears has reformed her short-lived bad girl ways and has since regained joint custody of her 2 boys and is now performing her own Las Vegas Show.ead and eventually lost custody of her kids. Spears has reformed her short-lived bad girl ways and has since regained joint custody of her 2 boys and is now performing her own Las Vegas Show.
Mischa Barton rose to fame when she starred on the hit show "The O.C." And as she became more popular, she partied more and more. Party girls stick together and Barton was often seen partying with Nichole Richie and Lindsay Lohan. Barton's partying took a more serious turn when she was arrested for a DUI and subsequently spent time in rehab. By 2013, Barton's wild nights were behind her and she is trying to revive her acting career.
Tara Reid's party girl ways don't seem to slow down as she is getting older. Reid is in her late 30s and is still partying up a storm. Reid figured out how to turn her partying into a money-making business by filming a show on E! called "Taradise," which was all about high-society vacation destinations and often featured Reid partying. It doesn't sound like Reid will ever change her ways.
Aside from Paris Hilton, Lindsay Lohan might be Hollywood's most famous partier. She was always scene leaving hot spots with other party girls like Paris Hilton and Britney Spears. From multiple car accidents and DUIs to multiple stints in rehab, Lohan went on a very strong downward spiral. Lohan couldn't seem to keep herself out of the tabloids. In 2014, Lohan said her partying ways are behind her and she is filming a documentary about living in NYC sober.
London's most famous party girl, Kate Moss has been partying for 20 years now. The model has been linked with party rockers like Pete Doherty and is currently married to guitarist Jamie Hince. Moss has been dropped from various fashion labels because of a controversy with drugs, but was soon cleared of all drug charges. The British It girl doesn't seem to be reforming her bad girl ways and she is still one of top-earning models.
One of the newest additions to the Hollywood party scene, Selena Gomez has been seen at all the hottest clubs. Since her split from JBeibs, Gomez has been spotted all over Hollywood with BFF Vanessa Hudgens. Gomez spent time at a rehab facility in 2014, but has never been confirmed for substance abuse. This Ex-Disney Star sounds like she will be enjoying her 20s for awhile.
Next article This Little Girl's Epic 'Brake-Up' Note Serves As A Warning To All Little Boys Out There. LOL.


visit here: Do you want to get arts and crafts supplies?
Things, which usually we like to carry out the most such as painting, drawing, decorating our bedrooms, etc., have course just about all related to arts and crafts. Making art pieces are definitely one of many most interesting jobs that people enjoy doing all of them as a activity or part of profession.Art routines and crafting are wonderful hobbies, which usually we do with our hands and by using creative perception in our human brain. We can enjoy the pleasure regarding expressing our inner feelings, feelings and our creativity transferred on paper or canvas.
If someone else appreciates our arts and crafts skills, we feel so content and happy. Art abilities can be increased by exercising and with passion that comes right out the deep thinking about our heart. Art skills may be used for admiring character, even performing and dancing, for appreciating something furthermore considered as an art and craft of arts. Not necessarily only the things which we make with our palms but what generate on the computer screen with the help of digital media can also give us several pleasure. Nonetheless, working with some media and equipment in our palms gives tremendous satisfaction and pleasure that is over and above expression.
Arts and crafts possess played a major role in almost all walks of life and now it has become a need of many men and women to health them emotionally with the aid of art and color therapies.
Arts and crafts help in developing learning and observational expertise in students. Very young children learn to imagine and create along with help of arts. The faculties provide their students all sorts of art information and art supplies to help them express, produce, and generate different art projects.
Art supplies needed in art classes or workshops can be purchased very easily through online art offer stores. You can find any kind of art related materials that you'll need. You can order at and online supply shop from place upon planet.
For more information please visit art supplies.


New Delhi, May 10 (UNI) The Left parties today rejected the Petroleum Minister Murli Deora's proposal for increasing the prices of petroleum products, saying the government should rather abolish all taxes on the import of oil.
''We have told the Petroleum Minister that we are opposed to any hike in the prices of petroluem products,'' CPI Parliamentary group leader in the Lok Sabha Gurudas Das Gupta told UNI.
In a presentation to Left leaders, the Oil Ministry said prices of petrol be raised by Rs 9.33 per litre and diesel by Rs 10.43 per litre, kerosene by Rs 17.16 per litre and LPG by Rs 114.45 per cylinder if they are to be brought at parity with import costs.
During the meeting with the minister in his chamber, the Left leaders spelt out the reasons for the opposition to any such hike.
''Why does the government want to increase the prices when it has claimed a high growth and while the fiscal budget is low...'' they asked.
CPI(M) general secretary Sitaram Yechury said the Manmohan Singh government should rather abolish all excise and customs duties on import of oil products or the common man would be badly hit.


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If Your Kids Miss Seeing Their Best Friends, This Sweet Personalized Book Will Lift Their Spirits
A Tale of Two Personalized Children's Book For Best Friends
As POPSUGAR editors, we independently select and write about stuff we love and think you'll like too. POPSUGAR has affiliate and advertising partnerships so we get revenue from sharing this content and from your purchase.
10 December, 2020 by Kate Schweitzer
My 6-year-old daughter hasn't played with her best friend in nine months. They've seen each other at carefully orchestrated, socially distanced meetups just enough for my kiddo to only ask, "Will I ever get to play with her again?," a handful of times, but whenever she has outwardly pondered her relationship with her pint-size pal, my heart would break for all the other children out there who are missing their best buds more than ever.
And although a book won't bring them magically together, a new hardcover personalized book called Tale of Two ($40) may be just the thing to make them feel connected — and to remind them that friendships are worth waiting for.
"One of the reasons I wrote the book for my little one was to remind her of her best friend who moved away when she was 3, so it's very apt that people are using it to connect little ones far away in 2020."
The 36-page story — which allows you to customise two different characters who play a fantastical game of hide-and-seek in the library and explore all kinds of classic books — launched in the US in September by a small publisher called Librio, and it's already by far the brand's most popular title of the seven currently available.
"One of the reasons I wrote the book for my little one was to remind her of her best friend who moved away when she was 3, so it's very apt that people are using it to connect little ones far away in 2020," Ed Russell, Librio's founder and CEO, told POPSUGAR. "It is super exciting to see it resonating with people in such a difficult year."
When creating the story, you can create your kiddo and their friend (or cousin, sibling, neighbour, or classmate!) by selecting skin colour, hairstyle and colour, and clothing, and the rest of the magic is done by Librio. They plop the kids into a series of adventures with pirates, unicorns, a very hungry caterpillar, and a boy named Mowgli, for starters.
The book is also available in soft cover ($28), and what's extraspecial about this particular personalization-style book is that if you want two copies (one for your kiddo and their bestie), you only need to click a link to instantly create a second copy of the book with the children's roles reversed. That way, they'll each have the same sweet story, with a slight twist!
It took me less than 10 minutes to create a book for my daughter and her friend, and even though I know my kid would love to find her actual pal hiding under the tree come Christmas morning, I hope that pageing through this book will somehow join them together in their imaginations. If it can make my kid feel like she's with her friend, even for a few minutes, well, that's the magic of reading combined with the power of friendship.
Tale of Two
from librio.com
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MyBroadband
Business Telecoms
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The cure should not be worse than the virus – SA businesses
Staff Writer7 April 2020
South African logistics and ecommerce businesses are asking Trade and Industry Minister Ebrahim Patel to allow the transport and delivery of goods with no human contact.
These businesses argue that allowing all goods to be transported domestically by professional courier companies will allow many businesses to continue operating.
They add that these sectors provide a valuable service to society while not adding undue risk to the further spread of COVID-19.
"We hereby request that you seriously consider allowing approved courier companies adhering to stringent preventative measures to transport all goods domestically," the letter reads.
"We can play a vital part in not only preventing the spread of the virus, but ensuring the well-being of South Africans – please allow us to do this."
The open letter to Patel has already been signed by over 1,000 logistics and ecommerce businesses and executives in South Africa.
Prominent signatories include uAfrica's Andy Higgins, Bidorbuy's Craig Lubbe, The Courier Guy's Stephen Gleisner, and Courierit SA's Marnie Dreyer Shaik.
The full open letter to Patel is published below.
The letter and signatures can be seen here: DearEbrahimPatel.co.za
The Minister of Trade and Industry
The Honorable Ebrahim Patel
Dear Honorable Minister,
Re: Request to allow the domestic transport of all goods with no human contact.
We write as concerned South African businesses operating in the local logistics sector. We are proud of the proactive response the South African government has taken to address the Covid-19 crisis, especially when compared to many other so-called first world countries.
We understand we are living in extraordinary times and saving lives can and must be our priority.
We however also believe the "cure" cannot be more detrimental to society than the virus itself and a balance needs to be obtained between extreme lockdown measures and protecting human well-being as well as the economy – a deterioration of which can also ultimately lead to the loss of lives.
We understand the most effective tool we have right now to fight the virus is to eliminate human contact as far as possible. We hope in time, ubiquitous testing with contact tracing, effective treatments and ultimately a vaccine are additional tools that will be instrumental in fighting the virus.
Right now the vast majority of South Africans remain free of the virus and are adhering to the regulations imposed by the government by staying at home. Families across the country are attempting to go on with their everyday lives, within the constraints of being home-bound. Those that can, have set up home offices.
Many children are likely to be schooled from home and will be requiring school supplies. With the onset of cooler weather, warm clothes and bedding is also needed. Access to non-essential home supplies will assist South Africans to continue with their activities at home for any period of lockdown.
Furthermore, the mental well-being of people can be improved by having access to certain non-essential goods such as devices for home entertainment and other items to remain occupied and healthy at home.
The logistics sector supports many micro businesses that would be able to continue to operate through the lockdown without human contact including:
All forms of eCommerce.
Online retailers – tens of thousands of online merchants are able to operate remotely.
Offline retailers – physical stores will be able to make use of courier services for home deliveries thereby preventing people from making unnecessary trips and reducing their risk of exposure.
For the most part, these micro businesses are not eligible for UIF or other government programmes available to support small businesses with many of these businesses currently on the brink of collapse.
As an essential service, the logistics industry's workforce is already deployed – fortunately most drivers own their own delivery vehicles and do not need to make use of public transport to get to work.
Unfortunately, with essential goods exclusively permitted to be transported, the costs to support this infrastructure are similar to a fully operational scenario but with income for these drivers significantly lower and currently unsustainable. Extending a lockdown with the current restrictions will ultimately result in job losses for many of these drivers.
The logistics industry has already taken proactive measures to prevent transmission of the virus:
Drivers are tested daily for any symptoms.
Drivers have been supplied with face masks.
Hand sanitiser is used before and after every collection / delivery.
Parcels are sanitised.
All interactions are contactless with sufficient separation between the driver and the sender/recipient.
We would argue that by allowing all goods – including those deemed to be non-essential – to be transported domestically by professional courier companies, will allow many businesses to continue to operate and provide a valuable service to society while not adding undue risk to the further spread of the virus.
We hereby request that you seriously consider allowing approved courier companies adhering to stringent preventative measures to transport all goods domestically. We can play a vital part in not only preventing the spread of the virus, but ensuring the well-being of South Africans – please allow us to do this.
Concerned Business
Now read: South African companies cutting salaries during the lockdown
courier services Ebrahim Patel Headline
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Pratt faculty: please show solidarity with Pace adjunct faculty by attending the following rallies. They have asked for our support. They have been bargaining for their first contract for the adjunct faculty for more than 3 years. Enough is enough!!! A number of Pratt faculty have already pledged to show up (weather permitting). Come to the rally and find us!
On December 11th and December 13th, Pace University is holding its annual "Employee Recognition Ceremonies." While we applaud our colleagues' accomplishments we also need to remember that among the honorees are many adjunct faculty who are in the ironic position of simultaneously being recognized and disrespected by the institution to which they have contributed so much. It is unacceptable for Pace to spend a few hours each winter passing out certificates, pins, and watches but spend the rest of the year wasting hundreds of thousands of dollars fighting its employees' right to union representation and a fair contract.
Join UAFP to tell President Freedman and the Pace Administration that REAL employee recognition means recognizing our right to a union and a fair contract! Let's send a message that New York State's working men and women are going to 'think twice' before attending or sending their children to an institution that wastes tuition, alumni, and public monies fighting its workers' right to a fair contract.
And click here for more information from the NYSUT website.
This entry was posted in Global News on December 8, 2007 by Suzanne.


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Playlist: Dave Brubeck
Image by: wikipedia
Dave Brubeck Quartet 1967. From left to right: Joe Morello, Eugene Wright, Brubeck and Paul Desmond.
Jazz musician Dave Brubeck passed away Dec. 5, 2012 at the age of 91.
WNYC's Fishko Files: An Hour With Dave Brubeck
From WNYC | Part of the WNYC's Fishko Files series | 59:00
An Hour With Dave Brubeck
"An Hour With Dave Brubeck" is another in Sara Fishko's series of conversations with musical figures. The interview for the program was taped in Brubeck's studio in Connecticut, this past spring. In the program, Brubeck discusses his childhood, musical influences (from jazz pianist Art Tatum to classical composer Darius Milhaud) and development. Music featured includes a very early recording of Brubeck "imitating" Tatum, Teddy Wilson and other pianists he admired; as well as some of the iconic live and studio recordings from his later days.
WNYC's Fishko Files: An Hour With Dave Brubeck | 59:00
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Dave Brubeck on Fighting Communism with Jazz
From Blank on Blank | Part of the Blank on Blank series | 05:11
Dave Brubeck took the stage at the Litchfield Jazz Festival in 2008 and during a conversation with John Dankosky, the host of Where We Live on WNPR, Brubeck told the remarkable story about fighting communism with jazz. Here's Dave Brubeck on going behind the Iron Curtain and what he saw--and heard.
Blank on Blank
Dave Brubeck on Fighting Communism with Jazz | 05:11
Dave Brubeck: Legacy of a Legend
Brief survey of pianist Dave Brubeck's long career.
For well over 60 years, pianist Dave Brubeck has been creating a sound that combines what he hears in the world around him with experimentation, playfulness and a lot of serious musicianship. His music - from Camptown Races to Take Five - are some of the most recognizable and influential pieces in Jazz history.
In this one-hour radio special, you'll hear stories and insights about the music from Brubeck himself, as well as collaborators Eugene Wright, Bobby Militello and manager & composer Russell Gloyd.
Dave Brubeck: Legacy of a Legend | 59:00
Dave Brubeck on Cultural Exchange
From National Endowment for the Arts | Part of the Jazz Masters Moments series | 01:59
Dave Brubeck on the importance of Cultural Exchange
NEA Jazz Master and pianist Dave Brubeck recalls how the US State Department sent US jazz greats abroad under President Eisenhower's cultural exchange program. Blended with audio of Louis Armstrong singing a song written by Brubeck's wife, Iola.
Dave Brubeck on Cultural Exchange | 01:59
Dave Brubeck on Russia and Jazz
Dave Brubeck reflects on the importance of jazz and foreign relations
NEA Jazz Master Dave Brubeck recollects the effect of American Jazz Ambassadors abroad. During the Jazz Ambassador program of the 1950s, Brubeck and other jazz greats like Armstrong and Gillespie were sent to global hot spots, such as Iraq, Iran, Pakistan and ... Russia!
Dave Brubeck on Russia and Jazz | 02:00
Dave Brubeck on the Oneness of Man and Music
NEA Jazz Master Dave Brubeck on the Power of Music and Exchange.
NEA Jazz Master Dave Brubeck celebrates the importance of music (jazz) and the oneness of man. The oneness comes from, he says, "the rhythm of your heart."
Dave Brubeck on the Oneness of Man and Music | 01:29
NEA Jazz Master Dave Brubeck on India
FOR MORE THAN 50 YEARS, NEA JAZZ MASTER DAVE BRUBECK HAS TRAVELED THE WORLD, FORGING RELATIONSHIPS THROUGH MUSIC. HE'S BEEN ONE OF AMERICA'S BEST REPRESENTATIVES OF CULTURAL EXCHANGE.
NEA Jazz Masters Moments highlight the jazz greats honored through the NEA Jazz Masters, a comprehensive program of jazz support that includes the NEA Jazz Masters Award, an NEA Jazz Masters tour with performances and educational activities, radio programming, a compilation CD, educational resources, and publications and reports. Nearly 100 radio segments feature eighteen NEA Jazz Masters, providing musical samples, historical information, and first-person anecdotes designed to give listeners added insight into the artists and their art.
NEA Jazz Master Dave Brubeck on India | 01:30
Jazz Ambassadors
Jazz Master Dave Brubeck on US Jazz Ambassadors of the 1950s
NEA Jazz Master Dave Brubeck discussed the inspirational and innovative Jazz Ambassadors program of the 1950s. Brubeck along with other jazz legends traveled the world playing jazz and promoting peace.
Jazz Ambassadors | 02:00
Jazz on the Bay: Tribute to Dave Brubeck, his music & legacy
From Melanie O'Reilly | 51:54
Irish jazz singer and radio host Melanie O'Reilly, visited the Brubeck Festival at the Brubeck Institute in Stockton, in 2007. In this program of "Jazz on the Bay", Dave Brubeck's music legacy is explored featuring interviews with the legend himself, his wife Iola and tributes from his close musical colleagues and friends including film actor/director Clint Eastwood, who also shares a little of his own involvement in jazz.
Jazz on the Bay: Tribute to Dave Brubeck, his ...
Melanie O'Reilly
Irish jazz singer and radio host Melanie O'Reilly , visited the Brubeck Festival at the Brubeck Institute in Stockton CA, in 2007. In this program of " Jazz on the Bay" , Dave Brubeck's music legacy is explored featuring interviews with the legend himself, his wife Iola and tributes from his close musical colleagues and friends including film actor/director and Chair of the Honorary Board of the Brubeck Institute, Clint Eastwood, who also shares a little of his own involvement in jazz.
The tributes recorded that day now have a powerful resonance after Dave Brubeck's recent passing, and capture the inspiration he generated through his music and legacy.
Jazz on the Bay , a series created by Melanie, is winner of a PPI Award (Irish National Radio Award) and is devoted to capturing the spirit of jazz in the San Francisco Bay Area, consisting of music and interviews by Bay area jazz performers, interspersed with their life stories, inspirations and personal anecdotes. Other programs in the series feature Chick Corea, Larry Coryell, Nancy Wilson, James Moody, Maria Muldaur, Frank Martin, Marion McPartland, Bobby McFerrin among others, and a special feature of Women of Jazz in the Bay Area.
Jazz on the Bay: Tribute to Dave Brubeck, his ... | 51:54


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The word "humility" means a modest opinion or estimate of one's own importance or rank.
Humility is the most essential quality of the Christian as it allows you to respond as you are being led by Christ.
This is telling us to live our lives, in our marriage, pleasing to God and not to desire the high praises of men.
Compromise is what marriage is all about so be careful with issues related to being opinionated.
Do you find yourself having to do things your way and not listening to your spouse?
If you want to be esteemed in God's eyes, in Isaiah there are three things God revealed that are first necessary.
When we humbly accept the love of God, our pride is challenged.
Humility will give you a deeper realization of your unworthiness.
Do you accept your God-given role of being subordinate to your husband? Keep in mind that God blesses us for submitting to this God-given role.
How do you respond when your spouse rebukes you? With anger?
You need to carefully consider the areas that have your spouse upset.
How do you act when your spouse disagrees with your opinion? Do you slander your spouse?
Do you try to understand the view point of others while realizing that God made everyone to think differently.
You need to have a humbling view about yourself, because you know your own secret faults and you know the true you.
Don't selfishly give yourself glory thinking that you are wiser, more talented or more gifted than your spouse.
You need to rejoice in the blessings of your spouse.
God often allows us to go through humiliating circumstances in our life.
Paul could not avoid or remove his fleshly thorns because they were necessary for his spiritual well-being to develop and maintain humility.
Let's take time to look at what our source of humiliation is?
It is healthy for us to have sources of humiliation.
Humiliating the proud is part of Jesus' ministry.
They tried to kill Jesus because he humiliated them.
They needed to be humiliated if they were ever to be saved.
What is your source of humiliation? Spouse? Children? Siblings? In-laws? Work? Co-workers? Friends? Finances? Marital Status?
The "Great Physician" may be trying to save your marriage by giving you medicine of humiliation.


text:
Marijn Lijffijt
SAGE Therapeutics, United States
LUIGI JANIRI
Catholic University of the Sacred Heart, Italy
Gaurav Bedse
Vanderbilt University Medical Center, United States
Front. Psychiatry, 05 April 2016
Sec. Addictive Disorders
Volume 7 - 2016 | https://doi.org/10.3389/fpsyt.2016.00054
Examination of the Addictive and Behavioral Properties of Fatty Acid-Binding Protein Inhibitor SBFI26
Panayotis K. Thanos1*, Brendan H. Clavin1, John Hamilton1, Joseph R. O'Rourke1, Thomas Maher1, Christopher Koumas1, Erick Miao1, Jessenia Lankop1, Aya Elhage1, Samir Haj-Dahmane1, Dale Deutsch2 and Martin Kaczocha3
1Behavioral Neuropharmacology and Neuroimaging Laboratory on Addictions, Research Institute on Addictions, University at Buffalo, Buffalo, NY, USA
2Department of Biochemistry, Stony Brook University, Stony Brook, NY, USA
3Department of Anesthesiology, Stony Brook University, Stony Brook, NY, USA
The therapeutic properties of cannabinoids have been well demonstrated but are overshadowed by such adverse effects as cognitive and motor dysfunction, as well as their potential for addiction. Recent research on the natural lipid ligands of cannabinoid receptors, also known as endocannabinoids, has shed light on the mechanisms of intracellular transport of the endocannabinoid anandamide by fatty acid-binding proteins (FABPs) and subsequent catabolism by fatty acid amide hydrolase. These findings facilitated the recent development of SBFI26, a pharmacological inhibitor of epidermal- and brain-specific FABP5 and FABP7, which effectively increases anandamide signaling. The goal of this study was to examine this compound for any possible rewarding and addictive properties as well as effects on locomotor activity, working/recognition memory, and propensity for sociability and preference for social novelty (SN) given its recently reported anti-inflammatory and analgesic properties. Male C57BL mice were split into four treatment groups and conditioned with 5.0, 20.0, 40.0 mg/kg SBFI26, or vehicle during a conditioned place preference (CPP) paradigm. Following CPP, mice underwent a battery of behavioral tests [open field, novel object recognition (NOR), social interaction (SI), and SN] paired with acute SBFI26 administration. Results showed that SBFI26 did not produce CPP or conditioned place aversion regardless of dose and did not induce any differences in locomotor and exploratory activity during CPP- or SBFI26-paired open field activity. We also observed no differences between treatment groups in NOR, SI, and SN. In conclusion, as SBFI26 was shown previously by our group to have significant analgesic and anti-inflammatory properties, here we show that it does not pose a risk of dependence or motor and cognitive impairment under the conditions tested.
The endocannabinoid system (ECS), which includes the lipid-derived neurotransmitters arachidonoylethanolamide (anandamide/AEA) and 2-arachidonoyl glycerol (2-AG) (1), has been widely studied (2) and implicated in numerous functions and diseases, including schizophrenia and Parkinson's (3), pain sensation (4), anxiety (5), learning and memory (6), emotion (7), obesity (8), and drug addiction (9). In the central nervous system, 2-AG and AEA primarily bind to the CB1 receptor (10). This discovery has led to the development of several synthetic compounds that can modify both the anabolism and catabolism of these endogenous signaling molecules.
Arachidonoylethanolamide is hydrolyzed by fatty acid amide hydrolase (FAAH), which is found in abundance throughout the CNS along with CB1 receptors and is the main enzyme responsible for AEA breakdown (11, 12). FAAH inhibitors, such as URB597, significantly elevate AEA levels and have been deemed effective in alleviating depression and anxiety symptoms (13) as well as pain and inflammation (14) in rodents, and at therapeutic doses, they lack the psychomotor deficits associated with direct CB1 receptor agonists (15). However, these compounds lack specificity (16). For example, FAAH is highly expressed in the liver (17), and systemic inhibition is linked with hyperglycemia and insulin resistance (18).
Due to the fact that AEA is a lipid ligand and that its catabolizing enzyme FAAH is localized on the endoplasmic reticulum and mitochondria, it has been deemed likely that a specific mechanism is responsible for the transport of AEA through the cellular cytosol for hydrolysis (19). Fatty acid-binding proteins (FABPs) have been proposed by Kaczocha et al. (20) as the means of transport for AEA. A particular focus has been on FABP3, 5, and 7 that are highly expressed within the brain and may provide a tissue-specific approach to elevating AEA. More recent findings have emerged supporting this claim and the possibility for this transport mechanism as a target for therapeutic modification (21–25). A recently developed compound, SBFI26, inhibits two of the most prevalent FABPs in the brain (FABP5 and FABP7) (21). Kaczocha et al. (26) have shown that SBFI26 inhibits visceral, inflammatory, and neuropathic pain by increasing AEA levels in rodent brain. FABP3 (heart-FABP) was not targeted (although it is also abundant in the CNS), because its deletion has been shown to induce age-related cardiac hypertrophy (27) and apoptosis and mitochondrial dysfunction in mouse embryonic cells (28).
The effect of increased AEA levels induced by SBFI26 has revealed a gateway for therapeutic potential beyond analgesia. The abuse of prescription and non-prescription opioids, such as heroin, has transitioned from a form of self-medication to a worldwide epidemic (29, 30). Given recent evidence of endocannabinoid modulation of pain and the abuse liability of many opioids, we hypothesize that manipulation of endogenous AEA signaling by SBFI26 might have important clinical potential. It is important first though to establish whether this compound may have abuse liability or exhibit some of the characteristic negative side effects of cannabinoid compounds.
In addition to the well-known "tetrad" of cannabinoid effects [analgesia, hypothermia, catalepsy, and sedation (31)], increased activation of CB1 can lead to aversive reactions and deficits in humans and animals, sometimes in a biphasic manner that contrasts the therapeutic effects of moderate increases in CB1 activation (32). For example, elevation of AEA via FAAH administration has produced anxiolytic effects (33), but high doses of CB1 agonists can produce anxiogenic responses (5). Accordingly center time in the open field, which is characterized as a measure of anxiolytic response, is significantly reduced in WT C57 mice administered THC, as is total open field locomotor activity at high doses (34). However, low doses of the synthetic CB1 agonist WIN55,212-2, URB597, and the "AEA transport inhibitor" AM404, which also raises AEA levels, did not decrease open field center time (35).
Learning and memory are also impaired by administration of THC in clinical studies (6, 36, 37) along with a variety of other CB1 agonists in rodents (38, 39). Both URB597 and the stable synthetic AEA analog R-(+)-methanandamide cause deficits in object recognition and performance in a variety of other short-term memory tests in a CB1-dependent manner (40, 41), and it was also recently demonstrated that URB597 impairs LTP in hippocampal brain slices from wild-type, but not CB1−/− mice (40). CB1 receptors are abundant in hippocampus (31), and AEA, but not 2-AG, has been deemed the ligand responsible for CB1-dependent memory deficits when in excess in this brain area (42). Given these findings, it is entirely possible that SBFI26 could potentially cause cognitive and learning deficits.
Similarly, recognition memory for social stimuli is also mediated at least in part by CB1 activity. Selective deletion of CB1 in specific neuronal populations has elicited similar effects on exploration in both the object recognition and social interaction (SI)/social novelty (SN) procedures, and the hippocampus has been primarily implicated in both (43). However, preference for SI and SN is mediated by a range of additional variables, such as olfactory, auditory, and ectocrine cues, as well as unshared neural correlates such as the involvement of the hormones oxytocin and vasopressin (44). In turn, although the tests for SI and SN can be used to operationalize aspects of learning and memory as well as anxiogenic responses (34), these paradigms are reflective of combinations of multiple behaviors, are considered a model for characterizing many different psychiatric disorders, and may reveal treatment effects not observed by testing recognition memory and exploratory drive alone (45).
Perhaps most importantly, pharmacological ECS manipulation has brought up the concern of addictive properties associated with the variety of compounds used to achieve this. Squirrel monkeys, for example, have been shown to self-administer AEA, an effect blocked by CB1 antagonism (46). Conversely, Scherma et al. (47) showed that while mice receiving intravenous injection of anandamide did not induce a conditioned place preference (CPP), the introduction of URB597 along with AEA resulted in conditioned place aversion. More recently, squirrel monkeys were also shown to self-administer AM404, and this compound also reinstated drug seeking for THC and cocaine (48). Similar to THC, it appears AEA might exhibit varying qualities under particular conditions that warrant further explanation. The present study examined the effects of the specific FABP5/7 inhibitor SBFI26 on CPP, a well-established model used to measure the rewarding properties of stimuli. Additionally, we studied a range of other behaviors previously shown to be affected by endocannabinoids in attempt to characterize any cannabimimetic side effects and potential clinical utility.
Male C57BL/6 mice (22–30 g, 9–10 weeks old, Taconic Farms) were used for all experiments (n = 66). The animals were single housed at room temperature (22°C) and in controlled humidity conditions and kept on a 12-h inverted light cycle beginning at 0900 hours with ad libitum access to water and food. Food intake and body weights were monitored daily. The animals were habituated to the experimental room for 1 week before testing. The experiments conducted herein conform to the National Institutes of Health Guidelines for the Care and Use of Laboratory Animals and were approved by the University Institutional Animal Care and Use Committee. Mice were divided into four treatment groups (vehicle, 5.0, 20.0, or 40.0 mg/kg SBFI26).
The FABP inhibitor SBFI26 was synthesized as in Berger et al. (21). The drug was dissolved in DMSO:cremophor-EL:saline (4% DMSO:10% Cremophor-EL) and administered intraperitoneally at a volume of 10 μl/g body weight. Doses used were determined by our previous report with SBFI26 (26).
The CPP apparatus used was a Habitest three-chamber model (Coulbourn Instruments; Allentown, PA, USA), as previously described (49). The present study used 1″ black and white stripes on two opposite walls in the left compartment, which contained crisscrossed half-inch metal flooring, whereas the right compartment consisted of perforated stainless-steel flooring with round holes on staggered centers, and 1″ black and white checkering on two opposite walls.
Locomotor and exploratory behavior were examined using an open field arena and the Tru Scan software photo beam tracking system (Coulbourn Instruments, Whitehall, PA, USA). The open field arena was a 16″ × 16″, and the perimeter was designated as the area within 2.5″ of the walls. The center consisted of the area within the perimeter.
Novel object recognition (NOR) testing also took place in the open field arena, and objects used were similar 5″ pink buckets and white vases. SI and SN testing took place in a plexiglass three-chamber apparatus, as described in Ref. (50), and used 5″ black wire cups to hold stimulus mice. Tests were recorded by digital video camera.
Conditioned Place Preference
The CPP paradigm was performed, as described in Ref. (49, 51), with some modifications (60 min conditioning sessions and 15 min pretest/test). SBFI26 or vehicle was administered 50 min prior to each conditioning session, and animals were returned to their home cage between injection and testing. The present study determined preference by calculating the percentage of time spent in one compartment compared to the other. This percentage is regarded as percent preference. Compartment preference for CPP was evaluated by comparing the percent time (time in one chamber divided by total time spent in both chambers) spent in the drug-paired chamber on preconditioning day to test day. Locomotor activity during CPP was also measured each conditioning day and binned for a time period of 1 h.
Open Field Activity
Locomotor activity and exploratory behavior were measured in an open field arena for 1 h, as previously described (52). Measurements included total distance traveled (FP Distance), time spent in center (Center Time), and time spent in a rearing position (VP Time). SBFI26 injections took place 50 min before the animal entered the open field.
Novel Object Recognition
Novel object recognition was carried out, as previously described (53). During the "familiar" phase, mice were placed in the center of the arena and allowed to explore two identical objects in either corner for 5 min. They were then returned to their homecage for 30 min, during which time one of the "familiar" objects was switched with a "novel" object. Subjects were then returned to the arena for the "novel" phase, and the proportion of time spent exploring the novel object over total exploration was scored for analysis. Buckets and vases were counterbalanced, as being considered the "familiar" and "novel" objects to avoid bias. SBFI26 injections occurred 50 min prior to the middle of the "familiar" run. Exploration of an object was considered to be occurring if the test mouse was within 1″ of the circumference of the object and oriented toward it. Recorded videos were scored by two research assistants, and scored were compared with an inter-rater reliability score.
Social Interaction and Novelty
Social interaction and SN were performed in a three-chambered arena with open doors, as described in Ref. (50), with minor modifications. Briefly, the test began with a 5-min habituation period in which the entire arena with both empty cups could freely be explored. Water bottles were placed atop cups to prevent climbing. The experimentor then introduced a conspecific male stimulus mouse to one of the cups for a 10-min "familiar" run (SI), followed immediately by the introduction of another conspecific male in the other cup in the "novel" run (SN). After 10 more minutes of exploration, all mice were returned to their home cages. SBFI26 injections occurred 50 min prior to the middle of the "familiar" run. Exploration of a conspecific was considered to be occurring if the test mouse was within 1″ of the circumference of the cup and oriented toward it. Recorded videos were rated with Top Scan software (Clever Sys Inc., VA, USA).
Paired-samples t-tests were used to calculate differences in preference between CPP preconditioning and test day for each treatment group, followed by a one-way ANOVA to detect differences in preference on test day between treatment groups. A two-way repeated measures (RM) ANOVA with SBFI26 dose and treatment (SBFI26 or vehicle) as factors was used to analyze locomotor activity throughout CPP conditioning. Open field parameters, NOR, SI, and SN were compared between treatment groups using one-way ANOVAs. All statistics and graphing were performed using SigmaPlot 11.0 software (Systat Software Inc., San Jose, CA, USA).
Paired-samples t-tests found no significant preference for the SBFI26-paired chamber with any of the treatment doses administered (see Figure 1); vehicle [t(12) = −1.18, p = 0.26], 5.0 mg/kg [t(15) = −1.87, p = 0.081], 20.0 mg/kg [t(15) = −1.79, p = 0.094], and 40.0 mg/kg [t(14) = −1.87, p = 0.082]. There was also no difference between treatment groups in mean preference on test day [F(3,56) = 0.060, p = 0.98].
Figure 1. A paired-samples t-test found no significant difference within any treatment group between percent preference for the drug-paired chamber on preconditioning day versus test day.
CPP – Locomotor Activity
A two-way RM ANOVA on average total activity between treatment groups and treatment days revealed no significant differences between groups [F(3,58) = 1.81, p = 0.16] or treatment day [F(1,58) = 1.11, p = 0.30; figure not shown].
No differences were revealed between treatment groups with respect to FP distance, a secondary measure of locomotor activity [F(3,53) = 0.36, p = 0.78]. There were also no differences in time spent in the vertical plane [F(3,53) = 1.63, p = 0.19] and time spent in the center [F(3,53) = 0.25, p = 0.86], and no significant interaction detected (Figure 2).
Figure 2. Floor plane distance traveled, vertical plane time, and center time were measured for all mice treated with either vehicle SBFI26 in the open field test. No significant difference was found between groups in all three parameters.
The proportion of time spent exploring the novel object did not differ with respect to SBFI26 dose [F(3,53) = 0.31, p = 0.82]. A one-way ANOVA also did not fine any significant differences in total object exploration time between treatment groups [F(3,53) = 0.78, p = 0.51; figure not shown].
Separate one-way ANOVAs were conducted to analyze the acute effects of SBFI26 on social behavior – defined as SI and SN. No significant main effect was found for the treatment of SBFI26 doses given [F(3,38) = 2.07, p = 0.12; figure not shown] on SI (interaction time with cup versus mouse). Similarly, no effect was found on SN (interaction time with familiar mouse versus novel mouse) for the SBFI26 doses given [F(3,38) = 1.579, p = 0.210].
By targeting the intracellular anandamide transporters FABP5 and FABP7, this study examined the effects of SBFI26 on CPP reward behavior, locomotor and exploratory activity in the open field, NOR, SI, and SN. Results showed that SBFI26 did not induce CPP nor aversion. In addition, SBFI26 did not have any effects on locomotor activity measured during CPP conditioning or in the open field. We also found that SBFI26 did not have effects on other behaviors measured.
THC and other CB1 agonists have been shown to exhibit a biphasic effect on reward and locomotion (54) as well as anxiety (55), and elevate dopamine (DA) in the nucleus accumbens such as all known drugs of abuse (56). FAAH inhibitors vary in their ability to produce rewarding effects and increases in DA concentrations in the nucleus accumbens; these effects are specific to which compound is being administered (57), as well as route of administration (58). Therefore, it was unknown if SBFI26 would have rewarding effects. The present study demonstrates that SBFI26 does not elicit the acquisition of reward or CPP behavior or CPA (aversion). Given that we recently reported the analgesic and anti-inflammatory properties of SBFI26 (26), the use of SBFI26 for pain management may provide future promise.
In addition, SBFI26 was shown not to have any effects on multiple test parameters of locomotor and exploratory activity, working memory as measured by NOR, and propensity for SI and SN. Specifically, SBFI26 did not produce differences in activity during the CPP procedure or the open field parameters of distance traveled, time in the center, or exploratory or rearing behavior (as measured by time spent in the vertical plane). Proportion of time exploring the novel object in NOR, and time spent exploring the stimulus mouse in SI and SN also revealed no differences between SBFI26 treatment groups. Due to the previously mentioned biphasic action of cannabinoids, we chose to utilize an effective dose of SBFI26 (20.0 mg/kg) for these experiments, as well as a low and high dose to tease out potential side effects across different degrees of FABP5/7 inhibition. SBFI26 did not cause any behavioral changes in the tests conducted at any dose.
These findings are in contrast to previous studies showing deficits in NOR induced by acute doses of CB1 agonists and R-(+)-methanandamide (41), as well as URB597 (40, 42), and decreased SI time in control mice (34). The latter finding is particularly intreaguing, given recent evidence that oxytocin elevates AEA in the nucleus accumbens to facilitate social reward (59). One possible explanation for the lack of significant differences in behavior in the present study is the degree to which SBFI26 raises AEA levels – URB597 has been shown to cause a fourfold increase of this endocannabinoid in mouse brain (5), whereas our group detected significant but smaller increases from SBFI26 (26). Therefore, SBFI26 may raise AEA concentrations to a degree that can still have therapeutic effects without detriments. Although we did not detect any anxiolytic effects of acute SBFI26 administration as measured by center time in the open field, this realm of research warrants further investigation given previous data of AEA elevation on anxiety (60).
These results are encouraging given the potential analgesic and anti-inflammatory properties of SBFI26, but more research is needed on the effects of SBFI26 testing on other drug abuse paradigms (i.e., self-administration, locomotor sensitization). Future research should also be directed at interactions with commonly abused drugs, such as cocaine, heroin, and marijuana.
All authors have significantly contributed to the research described in this article. Developed/planned the experiment: PT, SH-D, DD, and MK; performed the experiments: BC, JO, TM, CK, and EM; analyzed the data: PT, BC, TM, CK, AE, and JL; wrote the paper: PT, BC, and JH.
This research was funded by the Research Foundation of New York and NIH (1R01DA035923-01).
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59. Wei D, Lee D, Cox CD, Karsten CA, Penagarikano O, Geschwind DH, et al. Endocannabinoid signaling mediates oxytocin-driven social reward. Proc Natl Acad Sci U S A (2015) 112(45):14084–9. doi:10.1073/pnas.1509795112
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Keywords: endocannabinoid, FABP, anandamide, addiction, conditioned place preference, reward, memory, social behavior
Citation: Thanos PK, Clavin BH, Hamilton J, O'Rourke JR, Maher T, Koumas C, Miao E, Lankop J, Elhage A, Haj-Dahmane S, Deutsch D and Kaczocha M (2016) Examination of the Addictive and Behavioral Properties of Fatty Acid-Binding Protein Inhibitor SBFI26. Front. Psychiatry 7:54. doi: 10.3389/fpsyt.2016.00054
Received: 11 December 2015; Accepted: 24 March 2016;
Marijn Lijffijt, Baylor College of Medicine, USA
Luigi Janiri, Università Cattolica del Sacro Cuore, Italy
Gaurav Bedse, Vanderbilt University, USA
Copyright: © 2016 Thanos, Clavin, Hamilton, O'Rourke, Maher, Koumas, Miao, Lankop, Elhage, Haj-Dahmane, Deutsch and Kaczocha. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Panayotis K. Thanos, pthanos@ria.buffalo.edu


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Patriots Subscribe:
Curran's Patriots Talk Podcast
Tom E. Curran
Phil Perry
Look no further than the red zone as to why the Patriots can't score
By Phil Perry December 11, 2019 11:04 AM
FOXBORO — The Patriots are so infected by offensive issues right now that it's hard to pinpoint one and say it's the reason they've scored more than 20 points only once since Halloween.
But one area — one situation — stands out, because their struggles there are so glaringly obvious by the numbers. It's where the scoring happens: the red zone.
The Patriots went 1-for-3 on their red zone scoring chances against the Chiefs in Week 14, dropping their success rate in those situations to 48.08 percent for the season. That's 27th in the NFL, and places them behind teams like the Dolphins (16th), Bears (12th) and Bills (10th). It's also a significant drop-off from where they were just a year ago when they scored touchdowns on 62.86 percent of their red zone trips.
PERRY: Key takeaways from HBO's Belichick-Saban documentary
The one red zone score the Patriots had in last weekend's loss to Kansas City came on a 10-yard jet-sweep run with running back Brandon Bolden aligned as a slot receiver.
"It was nice to run it in there with Brandon Bolden," Tom Brady told WEEI's Greg Hill Show this week. "It's always nice when you can run it in. It's a lot easier than trying to squeeze it into those tight coverages in the red area."
The numbers would bear that out.
According to Sharp Football Stats, NFL teams have a 41 percent success rate collectively in the red zone when throwing this year. Their success rate when running in the red zone is 47 percent. From the 10-yard line and in, teams have a collective success rate of 48 percent passing. Their success rate from 10 yards and in when running the football is 52 percent.
Yet the Patriots — among the worst red-zone offenses in football this year — have frequently thrown the football more and more as they've gotten closer to the goal line.
LISTEN TO RICH EISEN & MATT CASSEL ON THE PATRIOTS TALK PODCAST:
On the season, they have 94 pass attempts inside the red zone versus 71 rush attempts. That's the most red zone pass attempts in football by a wide margin. (The Saints are next with 80.) But as the season has gone on, the run-pass contrast has become even more stark.
Over their last five games, going back to their loss in Baltimore, the Patriots have passed 39 times in the red zone (most in the NFL) compared to 19 rush attempts. When they've been inside the 10-yard line, they've passed 15 times compared to eight rush attempts. Inside the five, they've passed 13 times compared to three rush attempts.
"It's always best if you can hand the ball off and run it in," Bill Belichick told WEEI's Ordway, Merloni and Fauria Show last week. "It's harder to throw down there just based on the number of players they have on defense and the amount of space you have to throw on offense. Everything is a lot tighter.
"But the running game is tighter too because the secondary is closer to the line of scrimmage and safeties are like added linebackers so it's harder to get a hat on everybody. But the easiest thing to do is to hand the ball off and run it in if you can do that. That's always preferable than trying to throw it into a tight space with more defenders. But if they bring enough people up there or you're too close to the goal line and you have unblocked players then that's not really the answer either."
CURRAN: Why believe Belichick? The "Mona Lisa Vito" press conference
On this topic, everyone seems to agree. Running the football down close to the goal line is the most efficient way to do things. Even the advanced statistics — which often highlight the efficiency of NFL passing games — suggest that running effectively in the red zone and at the goal line is particularly valuable. According to this offseason piece by FiveThirtyEight.com's Josh Hermsmeyer, league-wide completion percentage drops about nine points from an opponent's 20-yard line to its three-yard line, making the ability to run down there critical.
So why have the Patriots bailed on their running game when down in close?
Their running game, in general, has struggled for much of the season and they currently rank 29th in yards per carry (3.5). That's one reason. But opposing defenses have also, at times, sold out to stop them on the ground in the red zone — probably because they like their chances to stop the Patriots' passing-game weapons.
Last week Josh McDaniels pointed to a play against the Texans when the Patriots had a first-and-goal situation at the seven-yard line. Against an eight-man box for Houston, Sony Michel took a handoff and was tackled near the line of scrimmage by a safety. Brady's next two passes went incomplete and the Patriots kicked a field goal.
"[The safety] was in the backfield, and that's the way we were getting played, quite honestly," McDaniels said. "Down there against them — and a few other teams the last so many weeks here — they're trying to make it difficult, trying to force you to do something, be one-dimensional . . .
"Our goal is to always try to be as efficient as we can be and do the thing that gives us the best chance to have success. I certainly am not opposed to being more run than pass, or more pass than run, if it's going to be successful for our team. I've got to do a better job at trying to find the right answers each week and put our guys in the right position and hope that we can go out there and execute well and get it in the end zone each time we're down there."
Perry's Report Card: Patriots WR fail to step up vs. KC
Last week against the Chiefs, the Patriots ran it successfully twice on their first two red-zone snaps. After a blocked punt, James White carried for nine yards to get the Patriots to the Chiefs 10-yard line. Then Bolden took it around the edge to score. Perhaps that was an indication of where McDaniels was hoping to go with his red zone attack.
On their next trip, it appeared as though the Patriots scored on a play that — as CBS color analyst Tony Romo pointed out — could be classified as a type of run play even though it was a short pass. Brady found N'Keal Harry going in motion for a very shallow under route, and Harry took it into the end zone after a couple of broken tackles. He simply wasn't deemed by the officials to have scored.
Three outside runs in the red zone. Three successful plays. Maybe there's something to work with there moving forward.
The Patriots had three more chances to punch it in after that officiating gaffe, remember. They ran for a loss of two after rushing to the line because they thought they'd scored on the Harry play. On second down, Brady threw to Jakobi Meyers, who dropped it. (Another red zone touchdown off the board.) On third down, Brady was sacked.
Why Van Noy thought booing was 'disrespectful'
On both dropbacks, both Julian Edelman and James White were doubled. On both dropbacks, the Chiefs started the down with what looked like well-populated fronts that might've discouraged run plays. Unable to run and unable to pass to their top options, the Patriots stalled deep in opponent territory.
Later in the game, on the final Patriots drive, they ran another pass-but-really-run play when White took an end-around pitch. He was tackled for a loss of two by an unblocked Chris Jones. Three passes followed, finishing with an incompletion to Edelman from the three-yard line that ended the game.
There's no easy fix to what ails the Patriots in the red zone right now. It's not as simple as more rush attempts and fewer passes. Defenses can dictate how things will go to an extent. McDaniels isn't going to ask his players to run head-first into a wall at the line of scrimmage simply because the numbers say it's better to run. But passing hasn't worked either.
Will the Patriots continue to go to the air and hope that a third option — a healthier Mohamed Sanu or Meyers or Harry, perhaps? — can emerge outside of Edelman and White? Or will they scrap the passing attack because it has them near the bottom of the league in red zone offense, and try to grind out touchdowns against imposing fronts instead?
Facing a long list of issues right now, executing key four-point plays — finding the edge that will lead to touchdowns over field goals — has to be at or near the top of the to-do list for McDaniels and his offense.
Curran's Power Rankings: Pats keep slipping in AFC>>>>>
Tags: Phil Perry, Tom Brady, Bill Belichick, Josh McDaniels, New England Patriots
By Justin Leger January 16, 2020 10:09 PM
Tom Brady doesn't officially become a free agent until the new league year begins on March 18, but the rumors are already flying about the New England Patriot quarterback's future.
A report surfaced earlier in the week that Brady and his family purchased a home in Greenwich, Connecticut. As NBC Sports Boston's own Tom E. Curran pointed out, that is false.
But that doesn't mean Brady isn't planning on making a move.
Thursday night on "Arbella Early Edition," Gary Tanguay revealed that a source told him Brady and wife Gisele Bundchen are looking to leave New England.
"I was told today by a source the family is planning to leave the area," Tanguay said. "The priority this time is to let the kids finish school this year, then they're gone."
Tanguay's report doesn't mean Brady is definitely leaving New England, but talks of him and his family looking to live somewhere else continue to gain steam.
If Brady indeed is moving on from New England and looking to start a new chapter, some of that could do with his desire to finally make the money he's worth in free agency.
According to Tanguay, Brady is "embarrassed" by the number of quarterbacks in the league that make more than him and has been fed up about it dating back to the summer, before he signed his contract extension.
Thirteen quarterbacks, including Brady's former backups Jimmy Garoppolo and Jacoby Brissett, make more on average annually than the six-time Super Bowl champion according to overthecap.com.
The truth is, we won't know for certain what's going through Brady's mind until the ink is on paper for the 42-year-old's new contract. Until then, it's going to be a stressful offseason for Patriots fans.
Curran: Is this newfound time a silver lining for Patriots?
Tags: Tom Brady, New England Patriots
By Jacob Camenker January 16, 2020 7:21 PM
Needless to say, it's unusual for the New England Patriots to have so much down time in January. Typically, they're playing in the AFC Divisional Round. And the AFC Championship Game. And often, the Super Bowl.
But this year, they were eliminated in the Wild Card Round for the first time since 2009. And now, they have a lot of time on their hands.
And while their early playoff exit was surely discouraging, the Patriots could stand to benefit from this extra time.
On the latest episode of the Patriots Talk Podcast, Tom E. Curran and Phil Perry discussed how the Patriots could utilize the extra time and the positive impact it could have on the organization.
Click here to subscribe to the Tom E. Curran Patriots Talk Podcast
Curran pointed out that because the team has so often been playing into February, their already thin staff has been stretched thin come draft season, which explains why the team has had some draft misses in recent seasons.
Really, it comes down to 312 days of prepreparation were sacrifice. And so for a bare bones organization in terms of both front office and coaching staff -- these guys have had shorter offseasons by a month on average than any other team in the NFL.
So on one hand, it's remarkable and it's a high-class problem. On the other hand, isn't it somewhat inevitable that you might have some draft swings and misses?
Perry agreed with Curran and brought up that the fact that the extra time off will give Belichick a real chance to thoroughly evaluate his roster.
I think for a team that is looking at a reboot, one of the sort of ironic things about that is that now you have time to really think that through in more detail and not to say that Bill Belichick isn't planning or looking at his roster, how it's constructed, how the contracts set up and trying to plan ahead. I'm sure he is doing that to a certain extent.
But you can only spend so much time on those things when you're getting ready for the divisional round, the AFC Championship Game every year, the Super Bowl every other year.
This surely makes sense and is definitely a positive for the Patriots. Perhaps with that extra time, Belichick can find a way to retain Tom Brady while significantly upgrading his supporting cast.
For more on the Patriots offseason plans, potential changes in their front office, and predictions for the AFC and NFC Championship Games, check out the latest episode of the Patriots Talk Podcast, which drops every Tuesday and Thursday as a part of the NBC Sports Boston podcast network.
Curran: Is this newfound time a silver lining for the Patriots?
Tags: Tom E. Curran's Patriots Talk Podcast, Phil Perry, NFL, Bill Belichick, Tom E. Curran, New England Patriots
Sources: Tom Brady and family preparing to leave New England Patriots Talk Podcast: What exactly are the Patriots up to right now? Patriots' Dont'a Hightower to miss 2020 Pro Bowl with injury; Bills LB to replace him Madden simulations predict NFL Conference Championship results Mike Vrabel thanks 'good friend' Tom Brady for motivating Titans on Instagram Patriots suddenly have time on their hands; here's how Bill Belichick will use it NFL rumors: Browns to interview Patriots' college scouting director for GM job Melvin Gordon wants James White to pass message on to Bill Belichick Report: Patriots bring in college QB-turned-CFL CB for workout Patriots' Stephon Gilmore named PFWA Defensive Player of the Year NFL reveals Super Bowl LIV referee, and it's a familiar face for Patriots fans Rob Gronkowski has fitting Twitter reaction to Luke Kuechly's retirement Patriots Talk Podcast: So with McDaniels back, does Brady follow? There is no Tom Brady house in Connecticut, says Tom E. Curran That 617 Life Podcast: Keeping Jimmy Garoppolo wouldn't have saved the Patriots Patriots QB Tom Brady pokes fun at Julian Edelman in new Instagram story Twitter couldn't resist comparing LSU QB Joe Burrow to Patriots' Tom Brady NFL odds: Where Patriots stand in opening Super Bowl LV betting lines revealed Ex-GM Scott Pioli provides evidence of Patriots' winning culture at Shrine Bowl Joe Burrow's record-breaking season for LSU has fitting Tom Brady connection


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presented by Nike Lacrosse
2022 NCAA Lacrosse Preview: No. 20 Bryant (Men)
Mon Jan 3 2022 | Matt DaSilva | College
PHOTO COURTESY OF BRYANT ATHLETICS
The 2022 college lacrosse season is nearly upon us. As is our annual tradition, we're featuring every team ranked in the Nike/USA Lacrosse Preseason Top 20.
Check back to USALaxMagazine.com each weekday this month for new previews, scouting reports and rival analysis.
NO. 20 BRYANT
2021 Record: 9-4 (5-2 NEC)
Final Ranking (2021): No. 16
Coach: Mike Pressler (16th year)
Mike Pressler called last year his most difficult as a college coach.
"And that includes the other thing," he said, referring to the fabricated Duke lacrosse case that briefly derailed his 36-year career in 2006.
"We didn't just coach lacrosse. We coached COVID," Pressler said. "It was about player safety. We met in Zoom. My office was my truck. We didn't get into the locker room for six months."
Bryant's rollercoaster 2021 season stalled three times due to COVID-19 protocols. Star attackman Marc O'Rourke missed the first eight games with myocarditis stemming from his own encounter with the coronavirus. Top scorer Logan McGovern, who has cystic fibrosis, also tested positive. The Bulldogs' rotation included eight freshmen who were forced into action because other players were either ill or injured.
"We were one positive test away from being shut down by the Rhode Island Department of Health," Pressler told USA Lacrosse Magazine's Patrick Stevens before the NCAA tournament last May. "Our goals changed. It wasn't game to game. It wasn't day to day. It was minute to minute."
NIKE/USAL PRESEASON TOP 20
1. Virginia
2. Maryland
4. Georgetown
5. Notre Dame
6. North Carolina
7. Loyola
8. Yale
9. Penn
10. Rutgers
11. Lehigh
12. Denver
13. Army
14. Syracuse
15. Johns Hopkins
16. Delaware
17. Drexel
18. Cornell
20. Bryant
O'Rourke's mid-April return sparked Bryant, which upended second-seeded Hobart and top-seeded Saint Joseph's in the Northeast Conference tournament to claim its fifth conference title since 2013. The Bulldogs, who in 2014 pulled off one of the biggest upsets in NCAA tournament history when they ousted Syracuse, gave Virginia fits in the first round before relinquishing a fourth-quarter lead in a season-ending 13-11 loss.
Playing with a heart monitor implanted in his left pectoral muscle, O'Rourke scored six goals in his first game back and finished with 21 goals in just five games.
"We talked about playing him half a quarter and resting him," Pressler said. "Guess what? That lasted about half a quarter."
O'Rourke returns as a third-year captain and one of four players utilizing an extra year of eligibility to pursue an MBA at Bryant and compete as fifth-year seniors. (Three others are graduate assistants.)
"He's right there with the best I've ever seen," Pressler said of O'Rourke, likening the big lefty to Zack Greer as a scorer and Matt Danowski as a dodger. "He's an underrated feeder too. We run him out of the box all the time."
Bryant boasts an enviable combination of top-down leadership and bottom-up depth, with a young core that could keep it in the top-20 conversation for years. McGovern (20 goals, 26 assists) was technically a third-year freshman per his eligibility in 2021. Faceoff specialist Jacob Alexander (57.9 percent), who outdueled All-Americans Zach Cole (Saint Joseph's) and Petey LaSalla (Virginia) as an injury replacement for Nathan Laliberte, was a second-year freshman. NEC Rookie of the Year Bennett Abladian (29 goals, eight assists), Kevin Groeninger (10 goals, nine assists) and Aidan Goltz (16 goals) were first years.
True freshmen accounted for more than 40 percent of the Bulldogs' offensive production last year.
"Those guys performed and came back with confidence," Pressler said. "From last spring to this fall, you could see it oozing through their pores."
Bryant purchased 12 new lockers in November to accommodate those looking to max out their eligibility in Smithfield. Pressler expects the current 54-man roster to balloon to more than 60 players next year. Senior goalie Luke Caracciolo (52.7 percent), the NEC championship MVP, already has rerouted his plans to enroll in the U.S. Army's Officer Candidate School to start his MBA and come back in 2023.
"For us, it's just the momentum," Pressler said. "The way we ended last year, that five-game stretch in the regular season, the NEC tournament and the battle with Virginia until the end—that momentum continued this fall. We really like the team we return in every spot."
TOP RETURNERS
Luke Caracciolo, G, Sr.
Bryant's best teams have always been strong up the middle, a formula that starts with a sound goalie. A fourth-year starter, Caracciolo was outstanding down the stretch, making 17 saves in the NEC semifinal win over Hobart and tying a career high with 18 saves in the conference final against Saint Joseph's. He also had a buzzer-beating save in a one-goal win over Merrimack. For the season, Caracciolo set new career highs with 147 saves and nine wins, posting a save percentage of 52.7 percent.
Logan McGovern, A, Jr.
Pressler said McGovern's pulmonologists credited his superior anaerobic conditioning and healthy eating habits for his avoiding any serious complications of COVID-19. "He is ripped," Pressler said. McGovern led Bryant with 26 assists and picked his spots as a shooter (20-for-58) to finish with a team-high 46 points in 11 games. He too has already committed to coming back in 2023 and should have additional eligibility beyond that.
Marc O'Rourke, A, Gr.
The fastest player in Bryant's Division I history to accumulate 100 points (it took him just 29 games) and just the fourth player to score at least 100 career goals, O'Rourke is an All-American caliber attackman who has not played a full season since 2019 due to the pandemic. An accomplished lefty, he has developed a strong right hand as well. O'Rourke had not practiced for six months when he came back to score six goals in his first game. Imagine what he will do with a full offseason and training camp under his belt. The sky is the limit.
KEY ADDITION
Cole Braun, M, Fr.
Pressler loves recruiting under-the-radar Californians (seven on the current roster) and prefers big multi-sport athletes with football experience. "Our MO is that we recruit a three-star recruit and try to make him a five-star player," he said. "We're in player development here." A 6-foot-6, 210-pound midfielder from Danville, Calif., Braun is also a bit of an entrepreneur. He started his first business building and selling websites in eighth grade, according to this article by ADVNC Lacrosse. Braun was Pressler's first recruit in his class. Consider us intrigued.
BREAKOUT CANDIDATE
Aidan Goltz, M, So.
Speaking of big California middies with backgrounds on the gridiron, Goltz, a 6-foot-2 specimen out of Newport Beach, started as a true freshman on Bryant's first line and was drawing long-stick matchups by the end of the season. "They took the pole off [two-time All-NEC midfielder] Trevor Weingarten and put it on Aidan," Pressler said. "Aidan doesn't even know a pole is on him. He'll just run by him." Recruited by Cal to play football as a split end, Goltz chose lacrosse, the sport his father, Ian, played growing up in Canada. Look for him to build on his 16-goal freshman campaign. Pressler also identified sophomore defenseman LaJhon Jones (31 ground balls, 15 caused turnovers) as a breakout candidate.
ENEMY LINES
What rival coaches say about the Bulldogs:
"Love the zone defense making you play slow, but they are willing to bust out from it and push the tempo. … Will always be superb at the FO X with Casey Brodersen on staff. … One of those teams I don't trust, but don't want to play either. Teams that have a lineup of guys I've never heard of — they're the ones that scare me."
POWERED BY LACROSSE REFERENCE
There is something in the water up in Rhode Island. When I calculated the most efficient players in Division I men's lacrosse, two of the top five were Bryant Bulldogs. You know the name Marc O'Rourke, but the player with the highest usage-adjusted EGA in the nation last year was his teammate, Isaiah Davis. I'll be watching to see if he's able to make a leap this season. — Zack Capozzi
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