text:
Election Intrigue in Belarus
Date: Sunday, March 19 @ 16:51:11 UTC
By Stephen Gowans, gowans.blogspot.com
The efforts of Western powers to overthrow Belarus' Lukashenko government will culminate in rallies planned for Sunday night in Minsk to protest the outcome of the presidential election Lukashenko is sure to win, not because the election will be rigged, but because Lukashenko is by far the most popular candidate.
Polls carried out as recently as last month, paid for by the International Republican Institute, the US taxpayer funded foreign policy arm of the Republican Party, show that support for the US-backed candidate, Aleksandr Milinkevich is "in the single digits," (1) while over half of voters back Lukashenko.
A January Gallup/Baltic Surveys poll found that 55 percent of voters planned to vote for Lukashenko, while only 17 percent planned to mark their ballot for the West's favored candidate.
So popular is Lukashenko, that the Los Angeles Times acknowledged that even his "fiercest opponents don't question the accuracy of independent polls that rate him the most popular politician in this country." (2)
That is, until now.
Milinkevich, whose campaign is being run by Terry Nelson, the national political director of the Bush-Cheney 2004 campaign (3) says the election "result has already been decided." (4)
This is part of a strategy to engineer a color revolution in Belarus, following the same script used in Ukraine and Georgia, to oust pro-Russian governments there. According to the strategy, election results will be declared invalid, followed by members of a Western-funded youth group spilling into the streets in a planned "spontaneous" uprising, demanding the government's resignation.
Last April 21st, Condoleezza Rice met with anti-Lukashenko groups in Lithuania, promising them money and demanding they coalesce around a single candidate (Milinkevich). "Rice's meeting," noted the Washington Post, "appeared to be aimed at preparing opposition officials for the elections, which Rice said would be an excellent opportunity to challenge the government." (5)
Up until the last few days, anyone following media accounts of the campaign would have learned that "Mr. Lukashenko's opponents seem not to be running an election campaign, as much as they are trying to organize an uprising" (6) and that Milinkevich "is campaigning not for the presidency but for an uprising." (7)
However, now that the election is upon us, the tone of the coverage has changed. Gone are stories about polling results that show Lukashenko to be miles ahead of Milinkevich. Now, warnings are issued. The election will be "manipulated, as expected." (8)
Nonsense. With his polling numbers in the single digits, the unpopular Milinkevich has no hope of winning the presidency, except by following the plans laid out for him last April by Rice.
Central to these plans is the youth group Khopits, modeled after similar youth groups put together by Western powers to bring down governments in Serbia, Georgia and Ukraine. Khopits gets its money from the US National Endowment for Democracy, its British equivalent, the Westminster Foundation for Democracy, and the Foreign Ministry of Germany, with "cash smuggled into Belarus in small amounts." (9)
Khopits' goal: To fill the streets after the elections results are announced, denouncing them as fixed, and demanding that Lukashenko step down.
Why does the West want Lukashenko to go? For the same reason Belarus' voters want him to stay. The economy.
Roughly 80 percent of Belarus' industry remains in state hands, the government "pursues a policy of pervasive state involvement in the economy," resists privatization, hinders foreign investment, and follows "active policies of important suppression and export promotion." (10)
The result is that under Lukashenko's tutelage, Belarus has become "a miniature version of the Soviet Union itself" (11) – hardly the kind of place to set hearts aflutter in the boardrooms of New York, London and Frankfurt.
Yet, however much Lukashenko's government makes investors and transnationals see red, both literally and figuratively, Lukashenko has "presided over a continual increase in real wages for several years, culminating in a 24 percent rise over the past 12 months."
(12) "He has also cut (Belarus's value added tax), brought down inflation, halved the number of people in poverty in the past seven years," and created "the fairest distribution of income of any country in the region." (13)
Is this the kind of guy you'd expect voters to be champing at the bit to dump?
1. New York Times, February 26, 2006.
2. Los Angeles Times, September 25, 2006.
4. Times Online, March 17, 2006.
5. Washington Post, April 22, 2005.
6. New York Times, January 1, 2006.
8. Washington Post, March 18, 2006.
10. The Heritage Foundation 2006 Index of Economic Freedom.
11. New York Times, January 1, 2006.
12. Times Online, March 10, 2006.
13. Ibid.


Mape CNC-2000XL 1999, 2 spindle Driller-router, 80Krpm Precise spindles. Completely overhauled.
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Can be supplied seperately or as multihead configuration. In excellent condition. Recently upgraded and refurbished. Warranty 6 months.


"The export business of Cork in Spain and Portugal during the 20th century: Changes and public interventions" is the title of the PhD thesis of the researcher Francisco Manuel Parejo Moruno, at Extremadura University. The work analyses the changes that have marked the world business of the cork industry in the 20th century, focusing mainly on Portugal and Spain in comparison with the other countries involved in this business. The thesis highlights the change of positions between the two countries in the worldwide leadership of the cork industry since the Spanish civil war of 1936. Portugal took first place and Spain moved to second position.


text:
package ideal.development.declarations;

public enum variable_category {
  LOCAL,
  INSTANCE,
  STATIC,
  ENUM_VALUE
}

redpajama_set_name: RedPajamaGithub


text:
North Korea Files Missile, Says Aiming for Nuclear Test
By Reuters	| May 15, 2017
Intercontinental ballistic missiles (ICBM) are driven past the stand with North Korean leader Kim Jong Un and other high ranking officials during a military parade marking the 105th birth anniversary of country's founding father Kim Il Sung, in Pyongyang April 15, 2017. The missiles themselves were shown for the first time inside a new kind of canister-based launcher on Saturday. The trucks upon which they are mounted are originally designed to move lumber. REUTERS/Damir Sagolj
North Korea said on Monday it had successfully conducted a newly developed mid-to-long range missile test on Sunday, supervised by leader Kim Jong Un and aimed at verifying the capability to carry a "large scale heavy nuclear warhead."
Kim accused the United States of "browbeating" countries that "have no nukes" and warned Washington not to misjudge the reality that its mainland is in the North's "sighting range for strike," the North's official KCNA news agency reported.
The North fired a ballistic missile that landed in the sea near Russia on Sunday in a launch that Washington called a message to South Korea, days after its new president took office pledging to engage Pyongyang in dialogue.
The missile was launched at the highest angle so as not to affect the security of neighbouring countries and flew 787 kilometres (490 miles) reaching an altitude of 2,111.5 kilometres (1,312 miles), KCNA said.
Experts said the altitude reached by the missile tested on Sunday meant it was launched at a high trajectory, which would limit the lateral distance it traveled. But if it was fired at a standard trajectory, it would have a range of at least 4,000 km (2,500 miles), experts said."The test-fire aimed at verifying the tactical and technological specifications of the newly developed ballistic rocket capable of carrying a large-size heavy nuclear warhead," KCNA said.
"If the U.S. awkwardly attempts to provoke the DPRK, it will not escape from the biggest disaster in the history, Kim said, strongly warning the U.S. should not to disregard or misjudge the reality that its mainland and Pacific operation region are in the DPRK's sighting range for strike and that it has all powerful means for retaliatory strike," KCNA said.
DPRK is short for North Korea's formal name, the Democratic People's Republic of Korea.
North Korea is believed to be developing an intercontinental ballistic missile (ICBM) capable of carrying a nuclear warhead and reaching the mainland United States. The U.S. military's Pacific Command said the type of missile that was fired was "not consistent with an intercontinental ballistic missile". The United Nations Security Council is due to meet on Tuesday to discuss North Korea's latest missile launch, diplomats said on Sunday, which was requested by the United States and allies South Korea and Japan.
U.S. Ambassador to the United Nations Nikki Haley called the launch a message by Pyongyang to South Korea after the election of President Moon Jae-in, who took office on Wednesday. "You first have to get into Kim Jong Un's head — which is, he's in a state of paranoia, he's incredibly concerned about anything and everything around him," Haley told ABC's "This Week" program, referring to North Korea's leader.
The report on the missile's flight was largely consistent with South Korean and Japanese assessments on Sunday that it flew 700 km (435 miles)and reached an altitude of more than 2,000 km (1,243 miles), which is further and higher than an intermediate-range missile tested in February from the same region, northwest of Pyongyang.
"North Korea's latest successful missile test represents a level of performance never before seen from a North Korean missile," Washington-based monitoring project, 38 North, said in an analysis issued on Sunday. "It appears to have not only demonstrated an intermediate-range ballistic missile (IRBM) that might enable them to reliably strike the U.S. base at Guam, but more importantly, may represent a substantial advance to developing an intercontinental ballistic missile (ICBM)," it said.
World hunger on the rise: More than 820 million at risk, UN says
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Meghan Markle, Pippa and Kate Middleton all smiles at the Wimbledon Women's Final
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redpajama_set_name: RedPajamaCommonCrawl


Did you ever have one of those strangely wonderful days? Today was a day like that for me.
I woke up this morning, no joints popped or cracked when I stretched.
Both kids slept 'till 8am, I actually read the whole newspaper and had two cups of hot coffee. It's not that I usually read the whole paper, it's just that I could.
When I checked my email this morning,there where only two messages telling me how to purchase "wealth building secrets" for $19.95.
The stock market took a big nosedive yesterday. I don't own any stocks.
We started to walk to the park today, but we never made it. We got a bit distracted. Gwen, who is three years old, seems to notice things I just never noticed.
"Where honey? I don't see it."
"Look Daddy, in the window!"
"Ah, frost on the window. A beautiful star indeed!"
"Can we make a snowman? He has to be big."
"We just made a snowman yesterday. You want to make another one today?"
"I want to make a big one!"
"Okay, where should we put him? Next to this snowman we made yesterday? He'll have a friend."
"It's a snowman baby. I want to make a daddy snowman."
"Oh, that's sweet. Let's make 'em big like your dad."
She sings "He's big, he's bad, he's my big bad dad...he's big..."
"Well thank you sweetie! I love you too. Where did that come from?"
Later when our snowman was happily guarding the house with the "snowman baby" we went inside and enjoyed some hot chocolate (well, 11 month old Ian had milk.) We had a nice fire going and Gwen was curled up on my lap giggling at George of the Jungle. Ian was banging on some blocks and singing to himself.
"You should daddy, I'm beautiful."
"I love Ian too. Is he beautiful?"
"Yes Daddy, he's just like you."
Indeed, I had a wonderful day. I'll never forget it.


We've all heard the stats. The workforce is shrinking while customer expectations are rising. We talk to Field service contractors every day who are facing the same challenges.
Few have navigated growth under these circumstances like Greg Crumpton. Greg is VP of Critical Facilities & Technology for Service Logic, with more than 36 years experience as a mechanical contractor. As one of the largest privately held HVAC/Mechanical Services companies in the U.S., Service Logic employs 1,200 technicians who service 100 million square feet of commercial, industrial and institutional real estate.
As part of our Field Talk series, Greg and I recently sat down to talk about the ways in which today's commercial customers are changing and what the field service industry needs to do to meet their evolving expectations.
Question 1: The expectations of customers are changing. From your experience, how should field service companies adjust?
Tip 1: Teach soft skills so young technicians communicate well with customers.
Question 2: How can today's field service contractors quickly set themselves apart?
Tip 2: Embrace digital technology to improve the customer experience.
[Greg Crumpton] "When I started out, communication with customers was mostly verbal with handwritten work orders where techs recorded what they did on the job.
By 2004, I was running my own company and bought the first laptop for one of our technicians to put mobile computing in the truck. Our little company set the tone for a higher level of customer communication within our geographic area. I've always embraced technology and that quickly taught me that our customers wanted more of it. Today, customers have digitized their businesses and they expect our industry to keep up.
Question 3: Off-site management has become more common in the commercial space. How does that change how customers do research and make buying decisions?
Tip 3: Educate off-site property managers by delivering interactive proposals that inform.
[Greg Crumpton] "In order for companies to compete they had to go to some kind of geographic model where people have more responsibility. One client used to have a property manager in Atlanta and one in Charlotte and another in Tampa. Today, there is a single southeast regional manager. When this guy needs pricing, he's got to solicit proposals via RFP. That's often a race to the bottom on pricing because you haven't built rapport with the client.
Question 4: In field service, there can be inherent distrust. How do your techs establish trust?
Tip 4: Show customers 'proof' of problems and solutions.
[Greg Crumpton] "Real human to human interaction comes down to good communication that builds a relationship and trust.


text:
Q: bash awk moving average with skipping I am trying to calculate a moving average with a data set. But in addition, I want it to skip a few number of data each time the average 'window' moves. For example, if my data set is a column from 1 to 20 and my average window is 5, then the current calculation is the average of (1-5), (2-6), (3-7), (4-8).....
But I want to skip a few data each time the window moves, say I want to skip 2. then the new average will be (1-5), (4-8), (6-10), (8-12)......
Here is the current awk file I am using, can anyone help me edit it so that I can skip a few data each time the window moves? I want to change the skip size and window size as well. Thank you very much!
#!/bin/awk

BEGIN {
    N=5          # the window size
}
{
    n[NR]=$1       # store the value in an array
}
NR>=N {            # for records where NR >= N
    x=0            # reset the sum variable
    delete n[NR-N] # delete the one out the window of N
    for(i in n)    # all array elements
        x+=n[i]    # ... must be summed
    print x/N  # print the row from the beginning of window
}

A: I think your ranges are not well specified, but you wanted to achieve can be done by parallel windowing as below
awk        '{sum[1]+=$1}
     !(NR%5){print NR-4"-"NR, sum[1]/5; sum[1]=0}
        NR>3{sum[4]+=$1}
      NR>3 && !((NR-3)%5){print NR-4"-"NR, sum[4]/5; sum[4]=0}' <(seq 15)

will give, you can remove printing ranges which it there for debugging.
1-5 3
4-8 6
6-10 8
9-13 11
11-15 13

for making window size and skip count variable
awk -v w=5 -v s=3 'function pr(x)    {print (NR-s-1)"-"NR, sum[x]/w; sum[x]=0}
                                     {sum[1]+=$1}
                   NR>s              {sum[s+1]+=$1}
                   !(NR%w)           {pr(1)}
                  NR>s && !((NR-s)%w){pr(s+1)}' file

first window always start at 1, second window starts at s+1.  This can be generalize for more than 2 windows as well, perhaps you can find someone to do it...

A: I see that you want to print MA every K ticks instead of printing for every tick (K=1). So you could add a condition NR%K==0 before printing in your existing code.
But it would be better to keep an array of N elements and overwrite them instead of deleting. Using NR%N as array index. This way, when K is not 1 and want not to calculate the MA, you will avoid checking how many elements to delete etc.
awk -v n=5 -v k=2       '{ a[NR%n]=$0 }
    NR>=n && (NR-n)%k==0 { s=0; for (i in a) s+=a[i]; print NR ":\t" s/n }' file

update condition to (NR-n)%k==0 for always starting from first tick where MA is calculated (that is for NR=n).

redpajama_set_name: RedPajamaStackExchange


Inflammation contributes to cardiovascular complications in type 2 diabetes, which are often characterized by microvascular alterations. We investigated whether myeloid-related protein 8/14 complex (MRP8/14) secreted by transmigrating monocytes and granulocytes may represent a biomarker for microvascular alterations in patients with type 2 diabetes and nephropathy.
MRP8/14 was measured in 43 patients with type 2 diabetes and nephropathy. Additionally, the inflammatory markers Interleukin-6 (IL-6), Tumor necrosis factor-α (TNF-α) and C-reactive protein (CRP) were quantified. To detect microvascular alterations proteinuria and retinal vessel caliber were used as classical and novel marker, respectively. Proteinuria was quantified by protein-creatinine ratio (PCR); retinal vessel caliber was quantified after retina photography on digitalized retina pictures.
MRP8/14 was positively associated with inflammation (r = 0.57), proteinuria (r = 0.40) and retinal arterial caliber (r = 0.48). Type 2 diabetic patients with MRP8/14 values above the median of 5.8 μg/ml demonstrated higher proteinuria and larger retinal artery caliber than patients with MRP8/14 values below the median (logPCR: -0.51 ± 0.52 versus -0.96 ± 0.46, P < 0.01; retinal artery lumen (μm): 178.3 ± 14.1 versus 162.7 ± 14.9 P < 0.01). Both groups did not differ with regard to metabolic factors and blood pressure. MRP8/14 was an independent predictor of retinal artery caliber in multivariate stepwise regression analysis (β = 0.607) and was positively associated with IL-6 (r = 0.57, P < 0.001) and TNF-α (r = 0.36, P < 0.05).
MRP8/14 – a marker for transendothelial migration – describes not only the state of inflammation in diabetic nephropathy, but additionally the degree of microvascular alterations in the glomerular and retinal bed. Therefore, MRP8/14 may be a potentially selective novel biomarker for microcirculatory defects in diabetic nephropathy.
Chronic inflammation contributes to type 1 and type 2 diabetes mellitus and is involved in the development of cardiovascular complications [1, 2]. Microvascular complications, which are largely defined by the presence and degree of proteinuria, are associated with inflammation . In the case of diabetic nephropathy proteinuria and systemic inflammation define the cardio-vascular risk . It would be interesting to correlate these changes to the microvasculature.
Retinal vessels represent a direct non-invasive measurement of vascular lumen diameter on the level of resistance arteries, hence the microcirculatory level . In this respect an enlarged retinal arteriolar and venular caliber is related to diabetes and systemic inflammation [6, 7]. The dilation of the retinal vessels has been attributed to an increased production of nitric oxide as a result of up-regulated nitric oxide synthase messenger RNA, secondary to release of cytokines such as IL-1 and TNF-α .
Apart from these direct effects of inflammatory markers on the microcirculation in diabetic nephropathy, little is known about the contribution of inflammation-initiated transmigration of monocytes through the arteriolar wall. We hypothesize that the myeloid-related protein 8/14 complex (MRP8/14), a marker of monocyte and neutrophil activation , predicts microvascular changes at an early stage. MRP8/14, also termed calprotectin, leukocyte protein L1 complex or cystic fibrosis antigen, is a heterodimer of two calcium-binding proteins (S100A8 and S100A9, also referred to as MRP8 and MRP14, or calcranulin A and B involved in calcium-dependent signaling, cell differentiation, cell cycle progression, and cytoskeleton-membrane interactions . MRP8 and MRP14 are primarily expressed in cells of myeloid origin, particularly in monocytes and neutrophils . Upon phagocyte activation, MRP8 and MRP14 form the MRP8/14 complex, which translocates to the cytoskeleton and plasma membrane, where it is secreted [12, 13]. This is an early event during transendothelial migration and thus represents an interaction of MRP-expressing neutrophils and monocytes with endothelium . Therefore we further hypothesize that systemic inflammation in diabetic nephropathy results in an increased transendothelial migratory activity of monocytes and neutrophils and hence microvascular changes in the glomerular and retinal vascular bed. It is the aim of this study to investigate in patients with type 2 diabetes and nephropathy whether the degree of proteinuria and retinal arteriolar lumen diameter are associated with markers of inflammation and endothelial transmigration. Furthermore we describe one patient demonstrating reduction of MRP8/14 and proteinuria under TNF-blockade, potentially mirroring the pathophysiological relevance of MRP8/14.
Forty-three patients with type 2 diabetes with nephropathy were recruited from the nephrological clinic Weissenburg. In the entire cohort, the simplified MDRD (Modification of Diet in Renal Disease) equation was used to estimate the glomerular filtration rate (eGFR (ml/min/1.73 m2) = 186 × (serum creatinine (mg/dl))-1.154 × (age)-0.203 × (0.742 if female) × (1.212 if black)). Proteinuria was quantified in spot urine by measurement of the protein-creatinine ratio (PCR). PCR was log-transformed to better approximate normal distributions. Additionally, cardiometabolic risk factors were evaluated and biological parameters measured, according to the recommendations of the American and European clinical practice guidelines. Anti-diabetic and anti-hypertensive medication was recorded including insulin-therapy, oral anti-diabetics, and the total number of antihypertensive drugs including differentiation of inhibitors of the renin-angiotensin system (RAS) or calcium channel blockers. The research has been carried out in accordance with the Declaration of Helsinki (2000) of the World Medical Association, and has been approved by the local Ethics Committee of the institution. Written informed consent was obtained from each patient after full explanation of the purpose, nature and risk of all procedures. One trained person measured anthropometric characteristics. For ≥3 hours before the examination, the participants refrained from heavy exercise, smoking, and alcohol or caffeine-containing beverages. The body mass index was weight in kilograms divided by height in meters squared. Venous blood samples, collected after overnight fasting, were analyzed by standard automated methods for lipids and blood glucose. Diabetes mellitus was defined as a fasting blood glucose level of at least 7.0 mmol/l or as the use of antidiabetic drugs.
IL-6, TNF-α (R&D Systems, Minneapolis, MN, USA) and MRP8/14 (Bühlmann Laboratories, Schönenbuch, Switzerland), were determined by commercially available ELISA using serum samples.
One trained person performed the retina measurements. Methods used to measure and summarize retinal vessel diameters from digitized photographs followed a standardized protocol described elsewhere . In brief, two 30° color retinal photographs of the left and two photographs of the right eye were taken at baseline. They were digitized by a high resolution scanner with standard settings (IMEDOS, Jena, Germany). Graders masked to the characteristics of participants used a computer program to measure diameters of all arterioles and venules in a specified zone surrounding the optic disc. These measurements were combined into summary indices – the central retinal arteriolar and venular equivalents – which represented the average arteriolar (CRAE) and venular (CRVE) diameters of that eye, respectively. These were additionally expressed as the retinal arteriolar-venular ratio (AVR). The ratio compensated for possible magnification differences between eyes, and an AVR of 1 indicated that arteriolar diameters were, on average, the same as venular diameters in that eye, while a smaller ratio suggested narrower arterioles. The AVR reflects the mean of the four photographs.
Aortic pulse wave velocity (aPWV) was assessed by sensitive transducers and the results were analysed using the Complior program (Complior, Artech Medical, Pantin, France) . First, patients rested in the supine position for 5 min. Brachial blood pressure was measured by an oscillometric device (Omron, Japan). Pressure-sensitive sensors were placed on the right carotid, radius and femoral artery. The distance between two sites (carotid-radius, carotid-femoral) was estimated automatically according to the body height of the patients. The time difference was determined from the delay of starting phase of the first wave between carotid and another site ("foot-to-foot method"). Aortic PWV was calculated by dividing the distance by the time difference. At least 10 signals were obtained twice and averaged to the results. In the case of an intra-patient variance of more than 10%, a third measurement was performed. Data were collected by a single observer (P.C.R.). The intra-observer coefficient of variation for carotid-femoral (C-F) PWV was 2.5%.
Programmed and validated blood pressure devices (model 90207; Spacelabs Medical, Issaquah, Washington, USA) were used to obtain blood pressure recordings at intervals of 20 min from 0700 to 2300 h, and every 30 min from 2300 to 0700 h. We calculated the within-subject 24-h means of the ambulatory measurements with weights according to the time interval between successive readings .
Data are expressed as means ± SD or percentages. The unpaired t-test, Mann-Whitney U-test or χ2-test were used for comparing the upper and lower MRP8/14 median group. Within the cohort, multiple linear regression analysis was used to evaluate which factors were independently associated with retinal arteriolar diameter. Data were analyzed using SPSS software (version 14.0). All tests were two-sided and a P-value < 0.05 was considered significant.
Patients with diabetic nephropathy and proteinuria are characterized in Table 1. They were stratified according to the median of the myeloid-related protein complex to assess whether MRP8/14 affects cardiovascular and metabolic characteristics (MRP8/14: median: 5.8 μg/ml, 25th percentile: 3.2, 75th percentile: 11.8, Table 1).
Values represent mean ± SD or percentages (%).
Anthropometric data and renal function were comparable between the groups. The distribution according to the median of MRP8/14 did not lead to difference in HbA1c and lipid profile. The use of insulin therapy was significantly higher in patients with higher MRP8/14 values (50 versus 17%, P < 0.05). The number of antihypertensive drugs and the use of calcium channel blocker (data not shown) and RAS-blocker were similar in both groups. MRP8/14 values had no influence on ambulatory blood pressure and arterial stiffness. In contrast, MRP8/14 values above the median correlated with microvascular alterations including increased proteinuria and enlarged retinal arterioles. Proinflammatory characteristics were prominent in patients with MRP8/14 values above the median.
Patients with diabetic nephropathy and proteinuria had a positive association between the degree of proteinuria and inflammation, although restricted to IL-6 (r = 0.39, P < 0.05, Figure 1). Other inflammatory parameters such as TNF-α and CRP were not significantly associated with the degree of proteinuria.
Bivariate correlations of Interleukin-6 (IL-6) and TNF-α with proteinuria and retinal artery caliber in patients with type 2 diabetes and nephropathy: A) IL-6 and proteinuria, B) IL-6 and retinal artery caliber, C) TNF-α and proteinuria and D) TNF-α and retinal artery caliber. We observed significant positive correlations for A) r = 0.39, B) r = 0.42 and D) r = 0.41. All correlations are given as calculated by Spearman correlation coefficient.
As second microvascular characteristic the luminal diameters of central retinal arterioles (CRAE) were investigated and associated with inflammatory markers. Here, IL-6 and TNF-α were positively associated with the lumen diameter of CRAE (r = 0.42, P < 0.01 and r = 0.41, P < 0.05).
MRP8/14 as marker for monocyte transmigration was positively associated with IL-6 and TNF-α (r = 0.57, P < 0.001 and r = 0.36, P < 0.05, Figure 2). Moreover, MRP8/14 was positively associated with the degree of proteinuria (r = 0.40, P < 0.05) and the lumen diameters of CRAE (r = 0.48, P < 0.01).
Bivariate correlations of MRP8/14 with A) Interleukin-6 (IL-6) and B) TNF-α as inflammatory marker and C) with proteinuria and D) retinal artery caliber as microcirculatory marker in patients with type 2 diabetes and nephropathy. We observed significant positive correlations for A) r = 0.57, B) r = 0.36, C) r = 0.40 and D) r = 0.48. All correlations are given as calculated by Spearman correlation coefficient.
Multivariable regression models were used to estimate the partial association between CRAE, inflammatory markers and MRP8/14 (Table 2). In patients with diabetic nephropathy and proteinuria, IL-6, TNF-α and MRP8/14 were significantly and independently associated with CRAE after adjustment for age, gender, BMI, glucose, 24 h SBP, and eGFR. This association remained significant for MRP8/14 and CRAE even after further adjustment for IL-6 and TNF-α.
Multivariate stepwise regression analysis for the central retinal artery equivalent (CRAE).
aModel adjusted for age, gender, BMI, glucose, 24 h SBP, eGFR.
A 48 year-old male patient with type 2 diabetes and nephropathy a HLA-B27 positive ankylosing spondylarthritis was diagnosed. Based on the activity of the ankylosing spondylarthritis a TNF-blockade with etanercept (50 mg/week s.c.) was initiated. Under this treatment we observed after 3 month of treatment that MRP8/14 as transmigratory marker decreased from 19.9 μg/ml prior etanercept to 3.2 μg/ml. After one year of treatment MRP8/14 remained low with 2.2 μg/ml. Secondly, we observed that proteinuria decreased under the TNF-blockade from 378 to 58 mg protein/g creatinine at 3 month and remained low after one year of treatment (49 mg protein/g creatinine).
Our study demonstrates in patients with type 2 diabetes and nephropathy that MRP8/14, a marker for transendothelial migration of monocytes and neutrophils, may predict changes in the microvascular bed of glomeruli and retina beyond inflammation. These changes are for the glomerular bed the degree of proteinuria and in the retinal bed an increase of arteriolar lumen caliber. Thus, MRP8/14 is a potential biomarker for microvascular defects in patients with diabetic nephropathy which may represent a pathophysiological relevant feature. Furthermore, these results implicate a potential deleterious role of increased arteriolar lumen caliber if associated with inflammation and transmigration in patients with diabetic nephropathy.
Diabetic nephropathy is characterized by proteinuria and low-grade systemic inflammation . Both factors have been associated with microvascular complications  and hence predict cardiovascular outcome . In this context, MRP8/14 was in our study positively associated with Interleukin-6 as marker for systemic inflammation  and TNF-α as marker for metabolic driven inflammation  in patients with diabetic nephropathy. This is of relevance as sequential migration of neutrophils is stimulated by TNF-α induced inflammation and can be reduced by inhibition of Interleukin-6 secretion . Thus, a causal relationship with the option to modulate the degree of microvascular damage may be suggested. Besides, the degree of proteinuria and retinal arteriolar caliber as conventional and novel microvascular factors were positively associated with MRP8/14. Thus, systemic MRP8/14 values seem to reflect not only the grade of inflammation, but also may define the microcirculation as the place of action. The microcirculatory action is not restricted to one organ as glomerular and retinal effects are observed. Moreover, Alwegg et al. demonstrated the local coronary release of MRP8/14 in acute coronary syndrome . Thus we suggest that the MRP8/14 activity reflects a generalized microcirculatory effect of increased transendothelial migration. In contrast, there is a lack of association between arterial stiffness measured by the gold standard of aortic PWV and MRP8/14. This suggests that no dominant effect of transmigration is present in the context of the macrocirculation. This further emphasizes MRP8/14 as a novel and potentially selective marker for microcirculatory effects in diabetic nephropathy.
Studies in diabetic nephropathy are fraught with difficulty, given the recognized associations with hypertension and dyslipidemia, both of which are known to influence the microcirculation . It is important to notice that our cohort after stratification according to MRP8/14 remains comparable for the lipid profile and 24-hour blood pressure measurement. Therefore, it is unlikely that MRP8/14 as marker for transendothelial migration is largely influenced by these two factors. Hence, enhanced MRP8/14 may describe a pathomechanism independent of hypertension and dyslipidemia in patients with diabetic nephropathy.
Furthermore, we describe one patient in whom TNF-blockade was initiated due to an ankylosing spondylarthritis. In this patient MRP8/14 and proteinuria measurements were available before and during treatment covering a period of 18 month. The measurements showed a decrease both of transmigration and proteinuria as marker for microcirculatory damage. These observations may be interpreted as pathophysiological relevant link between inflammation, transmigration and microcirculatory alterations. However, in the future this clearly needs to be investigated in detail.
Is a larger retinal arteriolar caliber in patients with diabetic nephropathy deleterious? In patients with type 2 diabetes the myogenic responsiveness is impaired. Schofield et al. demonstrated in pressure myograph experiments using resistance arteries of type 2 diabetic subjects that above a luminal pressure of 50 mmHg no reactive contractility was present whereas control subjects gave a blood pressure dependent myogenic response . As a consequence wall stress may rise resulting in vascular hypertrophy .
In our cohort of patients with diabetic nephropathy high MRP8/14 values are associated with larger arteriolar lumen caliber, which may reflect a failure to autoregulate blood flow efficiently . This may increase high blood pressure flow to target organs, effecting downstream damage, as determined in our patients by increased proteinuria particularly in subjects with elevated MRP8/14 levels. The failure of blood flow autoregulation may result in enlarged preglomerular afferent arterioles. This increases intraglomerular pressure with the consequence of proteinuria . Secondly, capillary transmigration may directly damage podocytes thereby aggregating capillary leakage which corresponds with proteinuria . These options raise the new speculation whether the defective myogenic response observed in type 2 diabetes is not only regulated by metabolic factors [27, 28], but is also related to the degree of local inflammation and transmigration.
In summary, we demonstrate that MRP8/14 as marker for transendothelial migration describes not only the state of inflammation in diabetic nephropathy, but additionally the degree of microvascular alterations. Therefore, MRP8/14 is a potentially selective novel biomarker for microcirculatory defects, which may play a pathophysiological relevant role.
KB designed, coordinated and wrote the manuscript. AB carried out the molecular genetic studies. SS performed retinal measurements. CRP performed macrocirculatory measurements.
FS carried out the MRP measurements. KK analyzed the retina measurements. ME performed statistical analysis. DS performed ELISAs. IL analyzed the retina measurements. UW designed, coordinated the manuscript. MB designed, coordinated and wrote the manuscript. All authors read and approved the final manuscript.


what I wanted a bit over a week until the seasons debute.
The seasons start will be special. Especially this year, as last year was hard. Just feeling your body totally out of it. And unable to hit back. I got some good anwers this winter during the 3000 meter that I am building myself back again – but outdoors is outdoors. It is then it really matters. While last years winter felt really short this one has been the opposite. Long…. – building, building, building and staying in Kenya.. I got an early start to the whole year (because I decided to stay out of racing after the European Championships last summer) which was what I needed. Hopefully that kind of buildup will pay off..


Locked Topic How do you build tension?
Locked Topic Are you sitting on stuff b/c your agent/editor is already working on something?
Locked Topic What is "high concept"?
Locked Topic Anyone ever have any luck with a query list?
Locked Topic Published Authors: How Many Submissions before Acceptance?
Locked Topic Writing multiple genres v. being known for a "style"


text:
Aline Mayrisch de Saint-Hubert (Ciutat de Luxemburg, 22 d'agost de 1874 - Cabris, 20 de gener de 1947), amb el nom de soltera d'Aline de Sant-Hubert, era una activista per als drets de la dona, filantrop, mecenes i escriptora luxemburguesa. Mayrisch va establir moltes organitzacions no governamentals i va ser presidenta de la Creu Roja de Luxemburg. Es va casar amb Émile Mayrisch.

Biografia
Saint-Hubert era la filla de Xavier de Saint-Hubert, i germana de Jeanne de Saint-Hubert, que es va cassar amb dos cosins successivament, polítics ambdós, Xavier Brasseur i Robert Brasseur. Es va casar amb l'industrial Émile Mayrisch, que fou el president del gegant de l'acer Arbed, el 15 de setembre de 1894. Van viure a Dudelange.

La primera de les moltes organitzacions que va establir va ser la "Lliga per a la Defensa dels Interessos de la Dona (en francès, Association pour la Défense des Intérêts de la Femme) el 1905. Saint-Hubert va oferir el patrocini d'aquesta entitat a la Gran Duquessa Marie-Adelaide, però s'hi va negar, ja que l'organització s'havia establert lligada a la religió catòlica.

El propòsit principal de la lliga fou crear l'establiment d'escoles públiques per a nenes, que va cobrar impuls amb la creació de l'Associació per a la creació d'escoles per a noies. Aquesta campanya va aconseguir un gran èxit el 1911, quan la  Cambra de Diputats va votar per unanimitat establir escoles de nenes amb fons públics a la Ciutat de Luxemburg i a Esch-sur-Alzette. Al mateix temps, Mayrisch va convèncer un grup d'altres prominents dames de Luxemburg per establir l'Association des Girl Guides Luxembourgeoises.

Era activa en el treball de les organitzacions de caritat com la Lliga luxemburguès contra la Tuberculosi, i la Creu Roja luxemburguesa, així com la defensa de la professionalització del treball social.

Amb l'esclat de la Primera Guerra Mundial, Saint-Hubert va establir un hospital a prop de Dudelange, per ajudar militars dels dos bàndols. Després de la guerra, va tenir un paper clau en la creació de la Lliga de Luxemburg contra la Tuberculosi, de la qual va ser vicepresidenta. Ella i el seu marit Émile van ser els principals donants de la Lliga i dels altres projectes que va encapçalar Ben aviat es va involucrar en la Creu Roja de Luxemburg, va ser nomenada membre del seu consell d'administració el 1926, i vicepresidenta després de la mort d'Émile el 1928, i el presidenta el 1933.

Ella i el seu marit es van mudar a Colpach el 1920, i després de la guerra van rebre molts intel·lectuals alemanys i francesos aquí en el que es va conèixer com a Cercle de Colpach, hi van passar gent com Paul Claudel, Jean Guéhenno, Jacques Rivière, Karl Jaspers, Bernard Groethuysen, André Gide, Jean Schlumberger, Ernst Robert Curtius, Annette Kolb i Richard Coudenhove-Kalergi. Van convertir la seva residència antiga de Dudelange en una llar per als nens, la  Fondation Kreuzberg .

Durant la Segona Guerra Mundial, va viure a Cabris, al sud de França.

El Liceu Aline Mayrisch, obert el 2001 a la Ciutat de Luxemburg, porta el seu nom en homenatge.

 Art i literatura
Aline Mayrisch tenia un gran interès en les arts i la literatura, i va veure a si mateixa com un mediador entre els mons culturals alemanys i francesos. A partir de 1898, va publicar articles sobre pintors alemanys i crítiques literàries, entre d'altres a L'immoraliste d'André Gide, al diari belga i avantguardista L'Art moderne. Va mantenir amistats i correspondències amb nombrosos escriptors i intel·lectuals, com André Gide, Jean Schlumberger, Jacques Rivière, Henri Michaux, Marie i Théo van Rysselberghe, Marie Delcourt, Alexis Curvers, Annette Kolb, Gertrude Eysoldt, Ernst Robert Curtius i Bernhard Groethuysen.

El 1914, va acompanyar a André Gide i Henri Ghéon a Turquia i el 1927, va viatjar a la Gironda i el Llemosí amb Ernst Robert Curtius. Al Castell de Colpach, va organitzar trobades francogermàniques en les quals André Gide es podia reunir amb Walter Rathenau i Ernst Robert Curtius. Aline Mayrisch també va introduir André Gide als textos de Rainer Maria Rilke i en la publicació d'un article sobre Rilke a La Nouvelle Revue Française, va ajudar a trobar un públic francès per a l'escriptor alemany. Va ser en aquesta mateixa opinió que va publicar articles sobre la situació intel·lectual a Alemanya després de la Primera Guerra Mundial, així com el seu relat autobiogràfic de viatges Paysages de la trentième année, text que a partir dels paisatges de l'illa de Còrsega i Islàndia, evoca l'enfrontament amb el buit, l'absurd i el no-res.

La seva novel·la inconclusa Andrée Reimenkampf no s'ha conservat per a la posteritat. En col·laboració amb Marie Delcourt i Bernhard Groethuysen, Aline Mayrisch també va traduir els sermons de la mística medieval de Meister Eckhart, L'enfant qui s'accuse de Jean Schlumberger i Le mythe de Sisiphe. Essai sur l'absurde d'Albert Camus. A la dècada de 1930, Aline Mayrisch va recolzar financerament la publicació a l'exili de Mass und Wert, de Thomas Mann. Les obres següents li van ser dedicades:  Das literarische Frankreich von heute  de Frantz Clément,  Les Cahiers de la Petite Dame  de Marie van Rysselberghe i  La vie d'Euripide '' de Marie Delcourt.

Referències

Escriptors luxemburguesos
Persones de Ciutat de Luxemburg
Morts a Provença-Alps-Costa Blava

redpajama_set_name: RedPajamaWikipedia


text:
3,161 views, 87 enquiries, and rented in 23 days.
Move and enjoy the fresh new surroundings
48A Bel Air Drive, Hillsborough, Auckland
Large basement storage
Brand new bathroom
Brand new kitchen
This 3 bedroom home has been completely renovated so is modern, fresh and clean.
The main bedroom has a double wardrobe. The second bedroom has a single wardrobe and would comfortably fit a single bed. The third bedroom has no wardrobe, but would fit a free-standing one and also comfortably fit a single bed.
The home is light, warm and dry. The sun streams into the elevated lounge, which opens onto a veranda, The home has ceiling and underfloor insulation, and a new heat-pump.
There is a large basement area, with a concrete floor, for your storage requirements.
The property has a secure fenced and gated backyard. It has a small backyard lawn and vegetable garden.
The location is only 500 metres from a bus-stop and the Motorway 20 Queenstown Road on and off ramps; and the airport is only 11 kilometres down the motorway. It's 500 metres from the Onehunga Bay reserve and two kilometres to Cornwall Park. The home is located close to many good schools, especially Catholic schools. https://www.educationcounts.govt.nz/find-school
VIEWING: Drive by the property first and please do not enter onto the property. To arrange a viewing inside email us your contact details.
OUR TERMS:
4 weeks' bond = $2680
1 week's rent advance = $670
Total moving in cost = $3350
We do not under any circumstances accept cheques.
Last updated 6 December, 2021
Nearby Auckland University of Technology (7.23km away), Auckland University of Technology - South Campus (12.79km away), Auckland University of Technology - North Campus (13.39km away), and The University of Auckland (7.33km away)


text:
Q: Why is my function returning null values So I have the following code and am wondering why the last 3 values are returning System.Collections.DictionaryEntry
    $count = 1
Function CreateHash($name, $address, $city, $state, $zip){

    return @{"name" = $name; "address" = $address;"city" = $city;"state" = $state; "zip" = $zip}

}
while ($count -lt 6){
    Write-host "This program will ask the user for the names and \n some other information about these people!"
    $name = Read-Host "Please enter the name of person $count"
    $address = Read-Host "Please enter the address of person $count"
    $city =  Read-Host "Please enter the city of person $count"
    $state = Read-Host "Please enter the state of person $count"
    $zip = Read-Host "Please enter the zip of person $count"
    $hash1 = CreateHash $name $address $city $state $zip
    Write-Host $hash1
    $count++
}

A: You're using the wrong syntax to call the CreateHash function.
CreateHash($name, $address, $city, $state, $zip)

should be:
CreateHash $name $address $city $state $zip

(parameter values are passed to Powershell functions as space-separated)


Origami instructions boaz butterfly. Origami Matthews Butterfly Step 1: Start with a 6 inch x 6 inch ( 15cm x 15cm) square origami paper, color side down. You should have the following to begin with. Easy Origami Butterfly Step 2: Fold the right and left tips of the upper half to the top.
Easy Origami Butterfly Step 1: Fold an origami boat base. Fold paper in half on the vertical axis.
Origami Matthews Butterfly Step 1: Start with a 6 inch x 6 inch ( 15cm x 15cm) square origami paper, color side down. Fold paper in half on the vertical axis. Easy Origami Butterfly Step 1: Fold an origami boat base.
You should have the following to begin with. Easy Origami Butterfly Step 2: Fold the right and left tips of the upper half to the top.


I accept donations, keeping my hand open to receive for those who would support my work, regardless how or why.
Whatever the reason, I want to say THANKS!
I am grateful for the opportunity to be of service, and I'm inspired that you are open to the flow.
The superhuman is endowed with cosmic consciousness to know that it is an androgynous ever-evolving interval of expansive cosmic enlightenment.


England has Darwin on their money. The US has a flying pyramid with the eye of Sauron on it.
Link to this: http://chan4chan.com/archive/92196/England_has_Darwin_on_their_money._The_US_has_a_flying_pyramid_with_the_eye_of_S auron_on_it.
Anonymous ^ call the cops then.


text:
Sky Go gets a makeover
Sky has revealed the biggest ever redesign of Sky Go. From this week in the UK and Ireland, Sky will start rolling out the new design, beginning with a new home page for the mobile app and web service.
Later in the year, Sky says the streaming service will "introduce new features to make the app more intuitive, surfacing more shows, sports and movies to the millions of customers who use Sky Go every month. It will become simpler to binge on box sets with a watch next episode feature and easier to find more movies to watch similar to ones you've been watching."
Michele Swaine, Director of Product Development commented: "This is just the start of a really exciting year for Sky Go – an app that's led the way in watching on the go and loved by millions of people around the UK. Both the redesign rolling out today and brilliant new features coming later this year are all part of our commitment to making finding the best TV brilliantly simple. So grab your phone or tablet, log in, and enjoy your favourite TV wherever you are."
The new home page rolls out immediately for Android users, with an iOS update to follow in February as part of a phased roll out. Customers who use the Sky Go web service will find the whole site and navigation has been overhauled from today with the new intuitive home page across all platforms.
Sky Go is available at no extra cost to all Sky customers, with content in line with subscriptions.
By Expat • UK Media News • • Tags: Sky, Sky Go
Channel 4 confirms Formula 1 races	RTÉ & Saorview partner with Freesat


text:
Koruza je lahko:

 Koruza, enoletno žito
 Koruza, priimek več znanih ljudi
 Koruza, tehnologija za brezžične optične povezave


When it came to winning a James Beard award, seven was indeed the lucky number for Dogfish Head Craft Brewery founder Sam Calagione.
Every year since 2011, Calagione has been nominated for the Outstanding Wine, Spirits, or Beer Professional in the prestigious James Beard Foundation Awards and, yesterday, he finally claimed a victory.
The winners were announced last night during an awards ceremony and dinner at the Lyric Opera in Chicago.
Calagione reportedly credited the award to "mostly" the work of the brewery's 250 employees.
From The News Journal: "People thought we were insane in the mid-1990s," he said, grinning about the brewery that's long been known for its "off-centered" beers. But Calagione got teary-eyed when he credited and thanked his business partner, best friend and "high school sweetheart" Mariah, his wife, who in 1995 helped him create the popular Sussex County business that has become a tourist destination in Delaware.
The James Beard Foundation awards the Outstanding Wine, Spirits, or Beer Professional to "a beer, wine or spirits professional who has made a significant national impact on the restaurant industry." Other finalists in 2017 included Rob Tod of Allagash Brewing Company in Portland, Maine; Diane Flynt of Foggy Ridge Cider in Dugspur, Virginia; Miljenko Grgich of Grgich Hills Estate in Rutherford, California and Aldo Sohm of Zalto Glass in New York City.
Calagione joins rare company as one of only three brewers — including former Anchor Brewing Co. owner Fritz Maytag and Brooklyn Brewery brewmaster Garrett Oliver — to win a James Beard medal since the awards were established in 1990.
Additionally, the Calagiones' seafood restaurant, Chesapeake & Maine, which opened in March 2016 in Rehoboth Beach, Dela., was named as a semi-finalist for the 2017 Outstanding Bar Program.
"We're also humbled and excited that James Beard recognized our innovative, culinary inspired bar program as it combines our love for our two favorite maritime regions into one delicious restaurant concept," Calagione said in the release.
Chesapeake & Maine will eventually be connected to Dogfish Head's new $4 million, 9,400 sq. ft. brewpub by a patio once a remodel at the company's original brewpub is completed.
Calagione's work has crossed over into the culinary world dating back to Dogfish Head's founding in Milton, Del., in 1995. In recent years, Calagione has collaborated with chefs Mario Batali and Joe and Lidia Bastianich at their combination restaurant and Italian food and wine marketplace, Eataly. At locations in New York City and Chicago, Dogfish Head collaborates in the brewing process at Eataly's Birreria restaurants and taprooms. Dogfish is also involved in a unique barrel-aging experiment at the Eataly location in Boston.
Dogfish Head's "off-centered brews" are now available in 34 states and Washington, D.C.


'We are safe and sound! Thank you to everyone who has expressed concern and thank you to the crew who managed the situation well. We believe that God will continue to keep us and Nigeria safe even as we go higher' he tweeted. Earlier today, a chopper conveying Vice-President Yemi Osinbajo to a campaign rally in Kogi State, crash landed in Kabba, Kogi State.
According to a tweet by his spokesman, Mr Laolu Akande, the VP continued on his campaign trip after the incident.
See more photos from the crash below.


text:
Q: Angular js escaping "é" in href attribute
Normally, this link redirects to #/wines/scope=rosé.
If I use angular, the link redirects to #/wines?scope=ros%C3%A9.
The source is not altered in any way by angular, only the behavior when clicking on it.
How can I make angularjs redirect to the link with the é instead of the %C3%A9?


Though players and fans may not have been satisfied with the results of last weekend's football game against Oklahoma University, the people working behind the scenes to coordinate the weekend events said despite the influx of visitors, the weekend went well.
Mike Seamon, director of game day operations, said more than 120,000 visitors made their way to campus last weekend, the highest total yet this year.
This increase was especially apparent in the parking lots on campus, which filled early in the day, Seamon said.
"Given the spectacular weather, we found that people wanted to get to campus early and experience all of the various game day activities," he said.
Seamon said the tunnel tour of Notre Dame stadium had 4,752 visitors last Friday compared to 3,890 on Michigan State weekend and approximately 5,000 for Temple weekend. The pep rally had 7,500 people in attendance, compared to 7,000 before Michigan State and nearly 12,000 for the home opener.
Additionally, the Friday football luncheon had more than 1,300 attendees, and students operating the campus pedal cab service provided more than 250 rides for guests on Friday and Saturday, Seamon said.
Phil Johnson, chief of police for Notre Dame Security Police, said his staff made no custodial arrests Saturday but issued two citations for underage drinking.
Seamon said no estimates were available on the number of Oklahoma fans who made it to the game, though they had a noticeable presence both on campus and in the stadium.
"They obviously traveled well, but it's impossible to guess how many bought tickets," he said.
Seamon said he and his staff are currently preparing for this weekend's "away-home game" against Arizona State University at Dallas Cowboys Stadium as part of the annual Shamrock Series.


text:
Rubin Observatory and Google will store astronomy data in the cloud
By Elizabeth Howell 22 December 2020
The Vera C. Rubin Observatory, formerly known as the Large Synoptic Survey Telescope (LSST), is currently under construction on Cerro Pachón in Chile.
(Image: © Rubin Observatory/NSF/AURA)
The new Vera C. Rubin Observatory in Chile has announced a three-year agreement with Google to host data from astronomy observations in the cloud.
Rubin and Google said that the collaboration, made public Dec. 9, would bring in a new generation of "large-scale scientific computing" projects that can be shared worldwide with Internet services.
Google will host Rubin's Interim Data Facility (IDF) that will collect preliminary data until the observatory becomes fully operational in 2023. The data will eventually be available to hundreds of scientists ahead of the prime observing phase of Rubin, known as the Legacy Survey of Space and Time, or LSST. (The observatory itself was previously called LSST, short for "Large Synoptic Survey Telescope," before it was renamed earlier this year.)
Related: 3,200 megapixels! The camera heart of future Vera Rubin Observatory snaps record-breaking 1st photo
"By using an established and trusted cloud infrastructure, we've been able to stay on track … to ensure we'll be ready to deliver high-impact science to our community when the telescope, camera, and data system are ready," Bob Blum, acting Rubin Observatory operations director, said in an emailed Google statement. "LSST is the one experiment that gathers data on the solar system, variable and exploding stars, the stars that make up our Milky Way galaxy, and the expansion of the universe itself."
The interim data set will be so large that users will use a browser-based science platform to use the information, avoiding the need for downloads, Google said in the statement. The LSST is expected to generate 500 petabytes (roughly 500,000 terabytes) of information, and the storage space of the interim data set was not released.
"The advancements we're seeing in astronomy point to the growing appetite for data that can only be supported by the cloud's scale and speed," Mike Daniels, vice president of Google Cloud's global public sector, said in the same statement. "By collaborating with Google Cloud, Rubin Observatory can build in more flexibility for the rising demand of astronomical data, while taking advantage of low-cost cloud data storage. This means Rubin Observatory can use more funds toward discoveries, instead of IT."
Related: A 'tsunami' for astrophysics: New Gaia data reveals the best map of our galaxy yet
Members of the science community can start accessing the interim data set in late 2021. Rubin is funded through the U.S. National Science Foundation, the U.S. Department of Energy, and with private funding raised by the LSST Corporation.
Follow Elizabeth Howell on Twitter @howellspace. Follow us on Twitter @Spacedotcom and on Facebook.


Glamorous Russian presenter Zhanna Veber, 29, was shot at close range by her estranged ex-husband during a row over custody of their son Dmitry, cops said.
A GLAMOROUS Russian TV presenter was killed by her estranged husband in front of their nine-year-old son, say police.
Zhanna Veber, 29, was shot at close range in a row over custody of their child.
She was killed by her husband Anatoly Leontikov, 36, with a supposedly "non-lethal" pneumatic weapon, according to police.
Their son Dmitry watched as his mother was shot.
The popular television personality in the Krasnodar region of southern Russian died on the way to hospital, say reports.
Leontikov then fled with with the boy, taking him to stay with his family before going on the run. He gave himself up to police yesterday.
Zhanna split from him two years ago but they were not officially divorced, say reports.
He arrived at her house and they quarrelled over his access to the child, which she had tried to limit, according to friends.
An unnamed friend of Zhanna said: "The scandal began because of the child.
"They have been separated for two years. Zhanna wanted to limit his access to the child."
He had been away working as a builder on construction sites near Moscow and when he returned, he had moved into her home for a while, but then left.
On 26 December, he returned and "broke a window" to gain access, said the friend.
"After she died, he took the boy to his relatives."
The friend said Zhanna was "ambitious" and had "big plans for her life".
Their visions "did not coincide".
She "wanted to move to a big city" while he "worked as a foreman building houses".
He was a former policeman who had a permit to carry the pneumatic gun, said the friend.
Her television station - Laba TV - ran a broadcast paying tribute to the dead presenter.


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I'd like to welcome our beautiful daughter, born February 15 2014, to the blogging world. She was 6 lb. and 19 inches long. We're so in love!
Woo-hoo!! Congrats and great pic!
Congrats Lindy!!! Wonderful little girl!
Congratulation, Lindy! Your new born daughter is so pretty!
She's beautiful! I'm so happy for you!
She is just amazing! Congratulations!


text:
TV cameras switch on to meaty topic
CELEBRITIES, staunch vegetarians and members of the public descended on a Glossop abattoir recently.
INDUSTRY icon: Butcher John Mettrick.
They were being filmed as part of a BBC programme intended to show the link between two moments often separated - the death of an animal and the consumption of its meat.
Butcher John Mettrick was asked to show a panel of 50 people through the processes he undertakes.
The award-winning trader, who is no stranger to the limelight following the success of the BBC's hit comedy the League of Gentleman, which used his butcher's shop, was approached because of his reputation in the industry.
"They wanted to show a working abattoir. They wanted to reconnect people with where food comes from - to have an animal fresh in their minds and show what happens," he said.
"It was quite a positive response. Some vegetarians said although they wouldn't start eating meat again they appreciated what we were doing, they saw it was a very skilled process."
So impressed by the abattoir were executives from the Meat Hygiene Service, that they are in talks with lecturers at Liverpool university for trainee vets to use it as a learning aid.
John said: "The deputy of the Meat Hygiene Service was very, very complimentary about the way the abattoir works and the hygiene levels. Because we have a viewing window as well, they are coming in from the university to see whether it may be useful for their course."
'Meat' is presented by award-winning journalist and presenter of BBC2's 'Full on Food' Richard Johnson, and is due to be aired on BBC3 in March.


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Category: Ireland
— geocaching, Ireland, travel —
8 National Trust Locations to go Geocaching in Northern Ireland | The Geocaching Junkie
Readers outside the UK may not have heard of The National Trust (NT), a conservation organisation founded in 1895 that works to protect and preserve places of historical importance. The NT promotes geocaching as an activity on their lands and either hides caches themselves, or works with local cachers to set up trails. Northern Ireland… Read More 8 National Trust Locations to go Geocaching in Northern Ireland | The Geocaching Junkie
— Ireland, travel —
5 Saint Patrick's Day Traditions We Celebrate in Ireland… and 3 We Don't | The Geocaching Junkie
In case you didn't know, Saint Patrick is the patron saint of the island of Ireland and is credited with bringing Christianity to these shores in the fifth century. He also banished all the snakes from the land, because why else would there be no snakes here? We celebrate Saint Patrick and all things Irish… Read More 5 Saint Patrick's Day Traditions We Celebrate in Ireland… and 3 We Don't | The Geocaching Junkie
— Ireland —
A Purrfect Visit to Cat Lounge Dublin | The Geocaching Junkie
The health benefits of owning a pet are well documented, and in cities like Tokyo, where having a dog or cat is not really an option, the popularity of cat cafés has exploded in recent years. We visited Calico Cat Café in Japan last year, but I wasn't overly impressed with the set-up, where treats… Read More A Purrfect Visit to Cat Lounge Dublin | The Geocaching Junkie
— geocaching, Ireland —
August Hike: Great Sugar Loaf, County Wicklow | The Geocaching Junkie
The thing about New Year's Resolutions is, you can make big declarations and everyone around you is likely to forget by February and subsequently nobody will hold you accountable. In other words, it's often easy to wriggle out of them. Not so when you publicise your intentions in a blog post. In January, I wrote… Read More August Hike: Great Sugar Loaf, County Wicklow | The Geocaching Junkie
The Gobbins Coastal Path: July Hike with a Difference | The Geocaching Junkie
Hailed as the most dramatic walk in Europe, The Gobbins coastal path at Islandmagee, County Antrim has been on my 'must-do' list ever since it was reopened in August 2015, after an almost six decade long closure. It was closed again in June 2016 due to increasing rock fall, but was partially opened in June… Read More The Gobbins Coastal Path: July Hike with a Difference | The Geocaching Junkie
Armagh: The Apple of Northern Ireland's Eye | The Geocaching Junkie
Last December, I spent a day exploring the city of Armagh and fell in love with its beauty and rich history. Luckily for me, cep99 is an Armagh native and subsequently knows all the great things the entire county has to offer. It was at her suggestion that THE_Chris and I joined her on Saturday last week for… Read More Armagh: The Apple of Northern Ireland's Eye | The Geocaching Junkie
The Great War & my Great-Grandfather | The Geocaching Junkie
When we were planning our recent geocaching trip to Bruges and the prospect of caching in France was brought up, I did a quick Google Maps search for the Terlincthun British Cemetery. It wasn't a million miles off our route and my road trip companions kindly agreed to a stop there. The cemetery, just outside… Read More The Great War & my Great-Grandfather | The Geocaching Junkie
8 Myths about St Patrick's Day & the Irish | The Geocaching Junkie
Today is Saint Patrick's Day – the one day a year that the world celebrates Ireland and 'Irishness'. It's the most widely celebrated national holiday in the world, with festivities going on in almost every corner of the globe. Just the fact that so many people celebrate makes me proud to be Irish. As I… Read More 8 Myths about St Patrick's Day & the Irish | The Geocaching Junkie
8 Beautiful Locations Associated With Saint Patrick | The Geocaching Junkie
Did you know that St Patrick's Day is more widely celebrated around the world than any other national holiday? 17th March is traditionally a religious commemoration of Ireland's patron saint, but is almost universally known as a cultural celebration of 'Irishness' and all things Irish. These days, Paddy's Day celebrations are bigger outside of Ireland than they… Read More 8 Beautiful Locations Associated With Saint Patrick | The Geocaching Junkie
Taking Geocaching to Extremes: Meet the Owner of Ireland's Most Daring Caches | The Geocaching Junkie
You know that exhilarating feeling when you finally catch a glimpse of an ammo can peeking out from that cacher's pile of rocks, after you've shed sweat and tears scrambling up a mountain and almost gave up several times? Or the feeling that you get after swimming in to a sea cave, then climbing on slippery rocks amongst various… Read More Taking Geocaching to Extremes: Meet the Owner of Ireland's Most Daring Caches | The Geocaching Junkie


The crew behind HBO's Big Little Lies already knows to stay out of Meryl Streep's way, since she essentially just forced her way onto the show even after season one had adapted the entirety of Liane Moriarty's original novel, but this new teaser makes it clear that the "Monterey Five" are going to learn a similar lesson on the show. Streep is playing Mary Louise Wright, the mother of Alexander Skarsgard's character, and here she tearfully confronts Reese Witherspoon's Madeline about what really happened to her son—though she gets the strangest feeling that Madeline won't actually be giving her the truth. That, combined with all the shots of every single character screaming at something, suggest that Big Little Lies won't be transforming into a chill hangout show for its mysterious second season.
Wait, so how did they make a 2nd season of Big Little Lies?


I'm thankful to live in one of those towns that only really exists in the movies or on a television show. The weather is beautiful a majority of the time, there is plenty to do, everyone (mostly) is friendly and it is close enough to commute to a larger city. I didn't always live here so I think that is partially why I have such a respect and admiration for it. There is rarely a time when there isn't something going on. There are movies and music in the park, festivals that celebrate the holidays, festivals that celebrate beer and wine and so much more. So many folks that grew up here say crap like "ugh I hate living in a small town." Too bad this isn't really a small town and you don't know what you're talking about.
Small towns don't typically have tourist attractions in them and enough things to do during the summer to keep the kids from terrorizing shopping centers. Small towns usually aren't listed in magazines as hot places to visit when vacationing in a certain state. Small towns don't have incredible concert venues that legends come and play at. I get so fired up about people ragging on this city because it is such a special place to me.
This place is where I was able to escape to when I was young and left a terrible situation. This place is where I grew as an actual person and felt like I could be myself. I learned to swim here, trust family and make friends, succeed and fail on my own. This place is where I met my husband and married him, bought my house and gave birth to my daughter. There will never be another place as special to my heart.
All of this is leading up to my thoughts on truly treasuring something. Coming from a background where we had nothing, I feel like I appreciate things more because I know what it is like to be happy to afford new clothes for school. You would think that someone who doesn't have much would want so much but when you know you aren't going to have it you just don't. This is where it gets tricky as a mom. Do we give things to baby P that I want her to have because I never had them, or do we restrict what we give her so she understands the value of things?
I want her to know the feeling of appreciating something as minute as where she lives because it's so beautiful. I was never given a car and my husband bought his himself and drove it until it broke down when we were together. That truck meant everything to him and buying my car on my own was such a milestone for me. Would it mean the same thing for her if she did it herself? Would it be different if we bought it with her and had strict rules that could get the car taken away? We have good friends who are going to pay for their kids' college because their parents paid for theirs and they don't want them to have debt immediately. I get that, I truly do and I think it is such a wonderful thing for them to do. However, I paid for my school myself and I never switched majors and only had to retake one course, which was an elective. I don't know if I would be able to say that if someone else had footed the bill.
How can we ensure that our children are thankful and appreciative of what they have?


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BMW Team RLL IMSA Mobil 1 Twelve Hours of Sebring and Year End Results
BMW Team RLL closed the 2020 IMSA WeatherTech SportsCar Championship with third and fourth place GTLM class finishes in today's Mobil 1 Twelve Hours of Sebring. With the GTLM class titles decided in the last round at WeatherTech Raceway Laguna Seca, BMW had its focus set on a second-place finish in the manufacturer championship standings as well as second and third-place finishes in driver points.
BMW Team RLL finishes 'Petit Le Mans' on the podium.
John Edwards (USA), Jesse Krohn (FIN) and Augusto Farfus (BRA) co-drove the #24 MOTUL BMW M8 GTE to a third-place finish in the 10-hour IMSA WeatherTech SportsCar Championship 'Petit Le Mans' at Road Atlanta (USA) to score the team's sixth consecutive podium finish. The trio led the GTLM class multiple times and completed 431 laps to finish 4.412 seconds behind the winning Porsche.
Double podium for BMW Team RLL at the "Charlotte Roval"
BMW Team RLL enjoyed success at 'Charlotte Motor Speedway'. Only GT cars lined up on the 'Roval', and they delivered a thrilling race in adverse conditions. Heavy rain and standing water on the track meant that the start of the race already scheduled for the evening had to be pushed back an hour to 21:05 local time.
A 2020 Processional Four Car Race for Mid Ohio
With Porsche withdrawing due to Covid-19 exposure, only a four car field contested the Mid-Ohio race this past weekend. Team RLL followed the two corvettes home and had a third-place finish by the No. 25 BMW M8 GTE of Connor De Phillippi and Bruno Spengler in the two-hour-and-forty-minute Acura Sports Car Challenge while John Edwards and Jesse Krohn finished fourth in the No. 24 BMW M8 GTE.
BMW Team RLL #25 Wins at Road Atlanta - #24 Third
BMW Team RLL stepped on the podium for the third consecutive IMSA race weekend capturing the team's 22nd victory. For Spengler, who joined the team as a regular driver at the beginning of the season, it was the first IMSA victory. De Phillippi and Spengler now stand third in GTLM driver points.
BMW Team RLL on the podium at Road America
BMW Team RLL returned to the podium in the fourth race of this season's IMSA WeatherTech SportsCar Championship at Road America (USA). After a chaotic conclusion to the 2:40-hour race, John Edwards (USA) and Jesse Krohn (FIN) came home third in the GTLM class in the #24 MOTUL BMW M8 GTE. Connor de Phillippi (USA) and Bruno Spengler (CAN) finished sixth in the second BMW Team RLL car, after suffering a mechanical issue shortly before the end of the race.
BMW Team RLL wins Daytona 24 Hours!
John Edwards (USA), Jesse Krohn (FIN), Augusto Farfus (BRA) and Chaz Mostert (AUS) took victory in the GTLM class at the wheel of the #24 MOTUL BMW M8 GTE at 'Daytona International Speedway'. At the head of the field, the BMW works drivers thrilled GT fans with magnificent overtaking manoeuvres to finish ahead of two Porsche cars in second and third place.
BMW Driver Lineup for the 2020 IMSA Season
Oil Leak Spoils Petite Le Mans for #24 RLL BMW
An oil leak in the early stages of the race caused a long pit stop for the #24 BMW M8 GTE, driven by Eng, Edwards and Krohn. The big gap of several laps couldn't be made up.
BMW #24 Finishes 2nd at Laguna Seca
BMW Team RLL came up 20 seconds short of delivering a third consecutive GTLM class victory at Laguna Seca. The two BMW M8 GTE racing cars finished second and fifth in today's Monterey Grand Prix. . The runner-up finish was scored by the No. 24 BMW M8 GTE, driven by John Edwards and Jesse Krohn, who started from the pole position and took the checkered flag 20 seconds behind the No. 66 Ford GT for our 10th podium at the track.
BMW Team RLL finishes disappointing 7th and 8th at VIR
BMW Team RLL finishes disappointing 5th and 8th at Road America
John Edwards is Crashed out of the Spa 24 Hrs in Torrential Rain and Fog
BMW Team RLL finishes seventh and eighth at Lime Rock Park
BMW Team RLL Finishes P2 and P4 at Canadian Tire Motorsport Park
BMW Team RLL #24 finishes fifth at Watkins Glen
Disappointment for BMW M6 GT3 teams at the 24 hrs of the Nurburgring
Edwards and Krohn in the ROWE Racing #99 BMW M6 GT3 2nd in VLN
BMW Team RLL finishes IMSA Sports Car Grand Prix at Long Beach in 7th and 8th
GT-Report.com Interview - John Edwards: "I was lucky I had my eye out for the Green"
John Edwards Makes Last Lap Pass for BMW VLN Victory !
John Edwards with Rowe Racing's programme for the first VLN race!
BMW Team RLL comes fourth and seventh in the GTLM class at the 12 Hours of Sebring.
John Edwards tests for WEC BMW team MTEK
BMW wins 24 Hours of Daytona
Copyright © 2016. John Edwards Racing. All Rights Reserved.
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(Montreal, Friday, 27 February 2009) – Pema Tsepak, age 24, died in police custody after being detained and beaten by Chinese authorities in Chamdo, Tibet. Pema was the nephew of Victoria resident "JG", the Canada Tibet Committee (CTC) announced today.
According to sources in Tibet, on January 20, Pema, Thinley Ngodrub, 24, and his brother Thargayal, 23, were attacked and detained as they walked towards local police headquarters in Tsawa Dzogang carrying a banner reading "Independence for Tibet," distributing fliers, and shouting slogans against Chinese rule. Thinley and Thargayal are also nephews of "JG".
Pema died some days after his arrest. The whereabouts and physical conditions of Thinley and Thargyal are unknown.
In January, Chinese authorities launched their 'strike hard' crackdown, which they described as "a people's war" to crush any potential protests in the weeks leading through Losar (Tibetan New Year) and the 50th anniversary of the Tibetan National Uprising on March 10.
In addition to Pema's death, sources in Tibet indicate that the Public Security Bureau in Lhasa has detained "5,766 suspects" for questioning; three Tibetan taxi drivers were injured after being fired upon by Chinese police following a scuffle with Chinese taxi drivers over parking space, and the detention of a single protester in Lithang County has prompted further protests by local Tibetans, a massive army deployment in the area, and arrests.
And today, a Tibetan monk was shot by Chinese police today after he set himself on fire at 1:40pm Beijing time in Ngaba town (eastern Tibet).
The CTC calls on Foreign Affairs Minister Lawrence Cannon to demand that the government of China immediately lift what is effectively a form of undeclared martial law in the region and to release all political prisoners detained by authorities.
Since last March's protests, the government of China has effectively locked down Tibet to foreign visitors, journalists and international observers. The CTC believes that the lock down has provided Chinese authorities with an unparalleled opportunity to conduct crackdowns and mass arrests.


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Control Z Season 3 Releasing on Netflix at July 6, 2022
Control Z Season 2 Releasing on Netflix at August 4, 2021
Silk Road (2021)
Misfit: The Series Season 1 will be on Netflix at October 16, 2021
Çukur S03E19 (Season 3 Episode 19) 86th
Billie Eilish: The World's a Little Blurry (2021)
Alpha Dog (2006)
Elite Season 5 Releasing on Netflix at April 8, 2022
The Hitman's Wife's Bodyguard (2021)
Uncle Frank (2020)
Vanguard (2020)
Rebel Cheer Squad: A Get Even Series Season 1 Releasing on Netflix at July 29, 2022


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Barnard Health Care
» Atopic Eczema
Sun, 20 Aug 2017 | Atopic Eczema
Eczema Free Forever
Only four RCTs have been published in full in three papers at the time of this summary (two trials in adults, n = 34 and n = 260, and two trials in children combined into one, n = 403).6-8 It is likely that there are many more unpublished and ongoing studies.
In the first study, 34 patients with moderate atopic eczema were randomised within a right-left body comparison study.6 Topical 1% pimecrolimus (syn. with ascomycin) was applied twice daily (n = 16) or once daily (n = 18) and compared with the corresponding vehicle cream for symmetrical lesions on one or other side of the body. The trial was very short (3 weeks) and all participants were adults. At the end of 21 days, those in the twice-daily pimecrolimus group showed a 71-9% decrease in baseline severity scores compared with 10-3% in the placebo group (P<0-001). The magnitude of benefit was less impressive in the once-daily pimecrolimus group, with a 37-7% reduction in the severity index in the active-treatment group, compared with a 6-2% reduction in the vehicle group (P= 0-002). None of the patients in the once-daily group (neither active nor placebo) showed total clearance of their lesions. This compared with 3 out of 15 patients showing total clearance in the twice-daily pimecrolimus group.
The large dose-finding RCT7 enrolled 260 adults who were randomised to 0-05% (n = 42), 0-2% (n = 46), 0-6% (n = 42) or 1% (n = 45) pimecrolimus, matching vehicle cream (n = 43) or betamethasone 17-valerate cream (n = 42) twice daily for 3 weeks.7 The results were
How might topical pimecrolimus be used?
analysed on an ITT basis and 23-5% discontinued from the trial (mainly because of treatment failure in the vehicle and low-strength pimecrolimus groups). Outcomes as assessed by a modified EASI score (a composite scale of the four signs of erythema, papulation/induration, excoriation and lichenification combined with extent, taking into account omission of head and neck) suggested dose-related improvements in all parameters in the 0-2%, 0-6% and 1% pimecrolimus groups but little or no benefit in those using the 0-05% strength. The greatest improvement was seen in the betamethasone group. At 12 weeks, the median percentage changes from baseline were -2-7, -14-8, -17^3, -27-6, -37-9 and -64-1 in the vehicle, 0-05%, 0-2%, 0-6%, 1% pimecrolimus and betamethasone valerate groups, respectively. Pruritus and patient-derived scores were similar, 88^1% of patients in the betamethasone group showed greater than 50% improvement compared with 53-3% in the 1% pimecrolimus group.
The third report8 evaluated twice-daily 1% pimecrolimus cream versus vehicle cream (randomised 2:1 respectively) for 6 weeks in 403 people aged 1-17 years with predominantly moderate atopic eczema affecting at least 5% of body surface area. This report represented combined data from two almost identical industry-sponsored multicentre studies in the US. At the end of the 6-week treatment period, those in the active group demonstrated clear gains in efficacy when compared with the vehicle group. For the primary outcome measure, 35% of those using 1% pimecrolimus, compared with 18% using vehicle were clear or almost clear according to the investigator, using an ITT analysis (P=0-05). Similar differences in favour of pimecrolimus were shown for other outcome measures such as EASI, and patient-reported itch.
Curing Eczema Naturally
Do You Suffer From the Itching, Redness and Scaling of Chronic Eczema? If so you are not ALONE! It strikes men and women young and old! It is not just
Eczema Free Forever Manual by Rachel Anderson
New Treatment of Rosacea
Eczema Holistic Treatment
Emollients and occlusive dressings
Case scenario 1 A child with atopic eczema of moderate severity
References for metastatic malignant melanoma
Intralesional corticosteroids Benefits
Photodynamic therapy PDT Efficacy
Unpublished, Treatment of the Erythema and Flushing of Rosacea


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Totescoop6 ~ The Horse Racing National Lottery
Totescoop6 ~ The Horse Racing National Lottery
Perhaps like me you shared in the jubilation of Agnes Haddock as Taranis came to win the totescoop6 handicap hurdle at Sandown last Saturday. By selecting the winner, Agnes secured herself a £248,288 bonus to add to the £410,332 she won by completing the totescoop6 the previous week. This king's ransom came out of a workmanlike £2 bet.
To win the totescoop6 prize fund a punter must pick the winners of six selected races on a Saturday.
Channel 4 had a camera fixed on Agnes as the race unfolded, and as Taranis jumped to the front at the last hurdle, viewers witnessed as her expression turned from one of hope and yearning to sheer exaltation at the line. Fantastic television!
My wife and I hugged each other and we were genuinely thrilled for the laundry woman from Cheshire. "It's like she's won the Lottery" said my wife. "No it's not!" I contested, "It takes skill and judgment to pick the right horses – the Lottery only needs you to pick 6 numbers at random."
The irony of Agnes' win was not lost on me: this luckiest of lucky ladies had picked her horses purely on folly, or because the names appealed to her!
Her first selection Simon won at 7-1 in the 2.25 at Southwell. Agnes said: "I picked it because I used to work with a really nice lad called Simon."
Her second choice was Exotic Dancer which Agnes chose because she had backed it previously, and it trotted up at 6-1 in the 2.45 at Cheltenham.
She got inspiration for the third winner — 6-1 Clouding Over in the 3.05 at Southwell — because it started to rain when she went into a BetFred bookies to place her bet!
Her fourth choice, Mountain, was a non-runner so her money automatically went on the favourite, Katchit – which won in the 3.30 at Cheltenham at 2-1.
Agnes's fifth and sixth horses Haggle Twins and Whispered Secret both romped home at 8-1. And finally… she arrived upon Taranis to carry her hopes for the Bonus because it was the number thirteen horse, and her birthday is the thirteenth.
Despite this fairytale win, I maintain that although the Scoop6 is the horse racing equivalent to the National Lottery, there are several distinct differences. The totescoop6 offers far better value than the Lottery. Serious punters can win a huge return on a tiny stake.
Although there is the argument that all sorts of charities benefit from the Lottery, it is strictly for mug punters. Unfortunately for the charities and Camelot, these punters are in short supply nowadays as more and more people are not in it to win it any longer. By contrast, 100,000 players every week are investing in the Tote Scoop6, in the belief that they are in control of their destiny regarding the wager. To an extent, they are correct, and they certainly have far more control than is the case in the National Lottery.
Odds of more than 14 million to one govern the Lotto, whereas Tote Scoop6 punters can reduce their odds dramatically, by making their own decisions regarding the horses that they nominate to carry their cash.
Returning to the basics of probability, the realistic price of selecting the first ball that drops out of the Lotto machine is of course 48/1 whilst (taking form analysis out of the equation) the price of any horse to win a ten-runner event (as an example) is 9/1.
To summarize, and this is only my tongue-in-cheek opinion, the Lotto balls are for losers, and fair-play to Agnes Haddock for winning the totscoop6!
About the author: Max Redd has been making a living betting on horse racing for over 10 years. He runs the Redd Racing betting advisory service which offers members a FREE trial and a 60-day money-back profit guarantee.
Category: Lottery
Tags: lottery, lotto


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Argentina's Mendoza province seeks investors for US$2.5bn potassium project
Bnamericas Published: Monday, October 24, 2022
Potash Financing Market Prices and Forecasts Commodities
Mendoza's natural resource company PRC and Swiss bank UBS are seeking investors for the US$2.5bn Río Colorado potassium project 200km south of the Argentine province's Malargüe city.
The 1.5Mt/y project is in an advanced stage and expected to start with 200,000t/y from 2023.
Investments so far went to infrastructure and facilities.
As a so-called plug and play asset, "the money arrives and the project starts. There are no new permits, no laws need to be changed. The project has all its papers absolutely in order," the CEO of PRC, Emilio Guiñazú, told the Club Minero podcast. He highlighted that previous project partners included Minera TEA, Rio Tinto and Brazil's Vale.
This last owner abandoned the project in 2012-13 at the onset of national crisis and as international potassium prices collapsed. Problems related to rail logistics added to the decision, Guiñazú said.
Río Colorado has 300Mt of proven and certified reserves, while solid price forecasts help financial sustainability.
In 2021, Vale and Mendoza agreed on an asset transfer. Overall, 78 wells were executed, which are protected by anti-corrosion systems, according to the project prospect.
The nearest road links are national route 40 and provincial route 189, which, however, require rehabilitation to ease logistics, Guiñazú said. "The project looks very attractive, and we are leaving ample room for potential investors to work and further improve the project equation."
Potassium prices rose after Russia's invasion of Ukraine. Although projected to fall slightly, they are expected to remain between US$400/t and US$600/t in the coming years.
"The market is there, prices are going to remain high, not at the level they are today, because it is bad for the world and we hope that the war in Europe will be resolved as quickly as possible. But even so, we see prices of over US$400/t," Guiñazú said.
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Argentine firm Minera del Altiplano S.A. (MdA), a subsidiary of US-based chemical manufacturer FMC Corporation, is engaged in the production of lithium derivatives, such as carb...
Company: Eramine Sudamérica S.A. (Eramine Sudamérica)
Eramine Sudamerica S.A. (Eramine), a subsidiary of French mining company Eramet, is focused on the development of lithium resources in Argentina. The company was founded in 2010...
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