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L'hyperoxalurie est une sécrétion urinaire augmentée d'acide oxalique. Elle peut être primaire ou secondaire. Les conséquences sont le risque de formation de calcul rénal en oxalate de calcium, voire la constitution d'une néphrocalcinose.

Causes

Les hyperoxaluries primaires
Elles sont d'originee génétique et correspondent à des déficits enzymatiques qui ont tous pour conséquence d'augmenter le taux d'oxalate dans le sang. Trois types sont décrits, le premier étant le plus fréquent :
 hyperoxalurie type 1, par déficit en alanine glyoxylate aminotransférase (ou AGXT) ;
 Hyperoxalurie type 2, par déficit en glyoxylate reductase–hydroxypyruvate reductase ou (GRHPR) ;
 Hyperoxalurie type 3, par déficit en 4-hydroxy-2-oxoglutarate aldolase (HOGA).

Environ 10 % des formes familiales n'ont pas de gène responsable identifié.

Les hyperoxaluries secondaires

Elles peuvent être dues à un excès d'ingestion d'acide oxalique. L'acide ascorbique étant un précurseur de ce dernier, une supplémentation régulière peut conduire à une hyperoxalurie, particulièrement en cas d'insuffisance rénale dialysée.

Elle se voit également en cas de résection chirurgicale de l'intestin : les sels d'oxalate sont pour la majeure partie sous forme insoluble et précipités grâce à des cations comme le calcium, l'argent ou le fer, ce qui les rend non absorbables par le tube digestif. Lorsque les graisses sont moins bien digérées ou absorbées (comme en cas de gastrectomie partielle, chirurgie bariatrique, dérivation jéjuno-iléale, résection iléale, prise d'orlistat ou toute autre cause diminuant l'absorption des sels biliaires et des acides gras), les acides gras de l'alimentation chélatent les cations comme le calcium et libèrent l'oxalate, ce qui le rend soluble, donc absorbable par le tube digestif. De plus, la malabsorption des acides gras peut être à l'origine d'une inflammation du côlon et augmenter sa perméabilité à l'oxalate. On parle alors d'hyperoxalurie entérique. D'ailleurs, dans ces cas, la prise alimentaire de calcium permet de diminuer l'absorption d'oxalate.

Clinique
Les symptômes sont essentiellement rénaux, avec formation de calculs rénaux riche en acide oxalique. L'évolution vers une insuffisance rénale par néphrocalcinose est possible.

Diagnostic
Le terme implique un taux d'acide oxalique élevé dans les urines. Ce taux est plus important dans les formes primitives que dans les formes seondaires. Ce taux peut cependant chuter en cas d'insuffisance rénale importante, et la mesure doit alors être faite dans le sang.

Le diagnostic des formes primitives se fait par séquençage des trois gènes impliqués.

Traitement
Une hydratation importante est recommandée ainsi qu'un régime pauvre en acide oxalique et riche en calcium. La prise de pyridoxine a un certain intérêt. l'alcalinisation des urines peut être proposée, par la prise de citrate de sodium ou de potassium.

Dans les formes primitives de type 1 et 2, une transplantation rénale peut être proposée.

Voir aussi
 Lithiase urinaire

Notes et références

Maladie en néphrologie
Urine


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Shelters overflow as more migrants opt to stay in Mexico
Nina Lakhani
Emily Rivas, a teenage girl from Guatemala, left her country after refusing the sexual advances of a gang member. After her boyfriend was killed by the gang, Emily and her family fled to Mexico where they have been granted refugee status. (Encarni Pindado/IRIN)
For years, Central Americans – mainly working-age men – have passed through Tapachula, near Mexico's southern border with Guatemala, en route to the US in search of a better life. But nowadays, the city's migrant shelters are overflowing with families seeking refuge. Only a tiny minority will find it in Mexico, where a lack of awareness about refugee rights, combined with pressure from Washington to detain and deport Central Americans, means only a fraction of those eligible for international protection are getting it.
Rather than try to reach the US border using increasingly dangerous routes to avoid detection, more and more migrants, like Vanessa Portillo and her boyfriend Carlos, both 18, are seeking to stay in Mexico.
Two failed bids to traverse the country ended in deportation back to El Salvador. On this, their third attempt, they've applied for asylum.
Portillo is nursing her newborn on the bottom bunk of a dormitory bed, surrounded by sympathetic strangers offering her advice on motherhood.
Portillo gave birth to her son in Tapachula. They had hoped to make it to Tijuana in northern Mexico where her mother lives but were twice intercepted by Mexican immigration authorities. This time, as Portillo was just days away from giving birth, they stopped in Tapachula and found refuge in one of the city's over-full migrant shelters.
Here, Portillo is learning to care for her son with help from older mothers from Guatemala, Honduras, and El Salvador – the three countries that make up Central America's Northern Triangle. An epidemic of violence between gangs, organised crime groups and security forces has made the region one of the most dangerous in the world outside of a war zone.
Mexican crackdown
In 2015, around 400,000 undocumented migrants entered Mexico through its porous southern border with Guatemala, and this year 450,000 are expected.
While most still try to reach the United States, an increasing number of families are seeking refuge closer to home in Costa Rica, Belize, and Mexico. This is largely down to an immigration crackdown launched in July 2014 under pressure from the US, after a record number of unaccompanied Central American children reached the Mexico-US border.
Since then, US aid has helped fund the deployment of thousands of Mexican troops who work alongside immigration agents, detaining and deporting potential refugees before they reach the US border.
Almost 200,000 migrants were detained by Mexican immigration agents last year, a rise of 130 percent from 2013. Nine out of 10 of those detained were from the Northern Triangle.
"Mexico's immigration 'policy' is to stop people from reaching the north; that's it, there's no other strategy or plan," Fermina Rodriguez, from the Fray Mattias Human Rights Centre in Tapachula, told IRIN. "No thought was given to what desperate people would do if they couldn't reach the US. Of course they would look for alternatives."
Portillo grew up in a semi-rural area north of El Salvador's capital, San Salvador, where one of the country's most powerful gangs, the Mara Salvatrucha (MS13), operates. She was still at school when she met Carlos, who lives in a nearby neighbourhood controlled by a rival gang.
In April, when Portillo was six months pregnant, gang members started harassing Carlos, who worked in a tortillería or tortilla shop, trying to force him to help them hide and deliver illicit goods. He refused. Over the next few weeks, the harassment turned into threats to kill him and Portillo.
Terrified, the couple fled one night and headed north to Mexico, hopping on and off buses, trying to avoid immigration officers. "Some drivers would drop us off before the checkpoints and promise to wait on the other side, but when we arrived they'd be gone. We walked many hours through the jungle. We were always scared of being caught," Portillo told IRIN.
They made it only as far as Acapulco, in southern Guerrero State, before federal police officers boarded their bus and detained them. The couple were held separately for a week in an ill-equipped detention centre, without any access to medical care. Portillo was seven months pregnant. No one told them about their right to apply for asylum.
They were transferred to Siglo 21 in Tapachula, the country's biggest detention centre, where busloads of Central American migrants apprehended at different points along the route are transferred every day. The vast majority are deported to their countries of origin within 24 hours.
Here, the couple were told about their right to seek asylum, but by this point they were exhausted and traumatised.
"I was locked in a cell with many women; some kept asking me for money. I was scared and just wanted to go home," said Portillo.
Vicious circle
The bus journey back to San Salvador took nine hours. The couple rested for two days and then set off again, but were caught and deported a second time. Demoralised and drained, they decided to stay in El Salvador and moved into Portillo's father's house.
But gangs operate in connected clicas, or neighbourhood cells, and within a few weeks the same gang members had found them and started threatening them again.
"I was more than eight months pregnant. I didn't want to leave home, but we had no choice. We were scared. We can never go back," said Portillo.
The young mum is adapting to her precarious situation but desperate to see her own mother. Carlos, who seems young for his 18 years, is terrified. "I need to get a job to look after them, but I don't know what I can do. I miss my mum, I miss home."
It will be at least three months before the couple know the outcome of their asylum application. If successful, they hope to become naturalised Mexican citizens, as their baby was born here.
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Encarni Pindado/IRIN
Vanesa Portillo and her teenage partner holding their newborn baby in a shelter for migrants in Tapachula
Last year, two thirds of the approximately 4,000 Central Americans who applied for asylum in Mexico were rejected by the Mexican Refugee Agency, COMAR. The number of asylum requests is expected to double this year and amid pressure from activists and better training, the rejection rate has dropped to one in three cases.
NGOs and the UN's refugee agency, UNHCR, are trying to raise awareness about refugee rights in the country, but there's much still to do.
Many of the fleeing Central Americans don't even know they could be eligible for refugee status, and those who are detained are rarely informed about their right to apply for asylum before being deported. Others are determined to reach the US, where they have family or friends.
There are concerns that too many genuine cases are still being rejected by COMAR, especially those who apply without support from lawyers, according to research by the Fray Mattias centre.
As Perrine Leclerc, director of UNHCR in Tapachula, put it: "Many of the people fleeing violence in the Northern Triangle need international protection, but most are still not getting it."
(TOP PHOTO: Emily Rivas, a teenage girl from Guatemala, left her country after refusing the sexual advances of a gang member. After her boyfriend was killed by the gang, Emily and her family fled to Mexico where they have been granted refugee status. Encarni Pindado/IRIN)
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*names have been changed to protect identities

redpajama_set_name: RedPajamaCommonCrawl


Rashmi Shreshtha, senior scientist of the International Centre for Integrated Mountain Development (ICIMOD), today said genuine participation of local people in planning hydropower projects, sharing of project benefits, and grievance redressal mechanisms can be the keys to expediting hydropower development in Uttarakhand.
She addressed a workshop titled 'hydropower irrigation nexus in upper Ganga headwaters' organised jointly by University of Arizona, USA, People's Science Institute, Dehradun, Shaheed Bhagat Singh College, University of Delhi, and ICIMOD. Shreshtha asserted that people were suspicious of hydropower projects and that was the reason even hydropower developers were also a frustrated lot.
University of Arizona Professor Dr Chris Scott presented an overview of the research project. He said social and environmental impacts from hydropower projects were often overlooked. "They have disproportionately greater impact on the marginalised populations, which is largely overlooked," he said.
People's Science Institute's Director Dr Debashish Sen presented field data to show that the impact of the projects in the Bhilangana basin was greater on the slopes where tunnels or channels had been constructed to divert water from the river to the power house. "These effects include loss of irrigated land, decrease in agricultural productivity, drying of springs and increased hardships for women who gather resources for daily sustenance for their families and cattle," Sen pointed out.
Uttarkhand Renewable Energy Development Agency's chief project officer AK Tyagi spoke about UREDA's electrification of remote rural areas using mini and micro hydropower projects. He emphasised the need for specific guidelines for environmental and social impact assessment of small hydropower projects.
Former Uttarakhand Chief Secretary SK Das called for aggressive social mobilisation so that developers, government and the community can work together for hydropower development.
Manoj Kesharwani from Uttarakhand Jal Vidhyut Nigam Limited said the new state policy in 2015 for hydropower development in the state had increased the Local Area Development Fund from one per cent of the approved project cost to three per cent.
Dr Piyoosh Rautela from Disaster Mitigation and Management Centre, Dr Prakash Nautiyal from HNB Garhwal University and Dr Malavika Chauhan of Himmothan Society participated in the workshop.


Data Centre service prodiver Sify Technologies has joined Google Cloud Partner Interconnect, a Google Cloud service that enables its customers to connect to Google Cloud Platform globally. Now, Sify will offer network connectivity services to Google Cloud in India. The company is already workig with Amazon Web Services and Microsoft Azure for similar services.
Google Cloud Interconnect Partner provides connectivity between customers on-premises network and VPC network through a supported service provider. A Partner Interconnect connection is useful if data center is in a physical location that can't reach a Dedicated Interconnect colocation facility or if data needs of a customer does not warrant an entire 10 Gbps connection.
Basically, Cloud Interconnect provides low latency, highly available connections that enable users to reliably transfer data between their on-premises and VPC networks. Also, Cloud Interconnect connections provide RFC 1918 communication, which means internal (private) IP addresses are directly accessible from both networks.
The company said that through Google Cloud's Partner Interconnect, Sify is enabling Google Cloud customers to connect with their offices, data centers and workloads in other public clouds, leveraging Sify's country wide IP VPN (MPLS) network, which reaches over 1600 Indian towns and cities.
In addition, Sify said that Google Cloud customers can also utilize its Data Center Interconnect services. This service is offered from 45 data centers in the country, including six of Sify's own carrier-neutral colocation facilities.


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Akai Amazon Fire TV Edition smart LED TV series launched in India: Price, specs and features
Akai has announced the launch of its new Amazon Fire TV Edition LED smart TV in India which includes TVs with display sizes ranging from 32-, 43-, 50-, and 55-inch dimension. However, it is the 43-inch version that is going to be available right now, with the rest in the series to be launched later on.
The new Akai smart TVs will be running Amazon Fire OS, which means the Fire TV experience is going to be available right out of the box. That way, users will be able to access popular streaming apps such as Prime Video, Netflix, YouTube, Disney+ Hotstar right away.
Users will also be able to avail of the Live TV feature that was introduced to Fire TV only recently. This will allow users to get access to Live content from OTT apps such as SonyLIV, Voot, Discovery+, and NextG TV. This, in turn, will open up access to more apps such as Sony SAB HD, Colors HD, Nick HD+, DD National, News18 India, MTV Beats HD, and so on.
Coming to specs, the new Akai Fire TV Edition series offers Full HD resolution as well as 178-degree wide viewing angles. The TVs have 60Hz refresh rate while a Durable A+ Grade DLED ensures top-notch picture quality. Further adding to the viewing experience is the integrated 20-watt speakers with Dolby Audio and DTS Tru Surround that together makes for the most optimum listening pleasure.
While the specifics haven't been revealed though Akai said the new Amazon Fire TV Edition TVs come powered by a quad-core processor that provides for lag-free performance. For ports, there are three HDMI ports, a USB port and an IR port that will allow integrated control of connected devices such as the DVD or STB player. The TVs also come bundled with the Alexa enabled smart remote control that can be used to launch channels, search content, control other smart connected devices, besides exploring the thousands of other Alexa skills easily via voice commands.
The 43-inch Amazon Fire TV Edition smart LED TV is available in India starting November 26, 2020, from Amazon.in. The 43-inch version is priced competitively at Rs. 23,999. Though the launch dates haven't been announced yet, the 32-inch smart TV is priced Rs. 14,999 while the price of the 50-, and 55-inch Ultra HD smart TV is yet to be revealed.
Tags: Akai


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Dane Dems is affliliated with the Democratic Party of Wisconsin. The modern Democratic Party in Wisconsin got its start in 1949, when the progressive wing of the state's Republican Party broke away and joined Wisconsin's Democratic Party. Over the next decade, Democrats, invigorated by the new blood brought into the party by those progressives, racked up an impressive series of wins. This included the election of the first Democratic governor and U.S. senator, knocking out Joe McCarthy in doing so.
Since that time, the Democratic Party of Dane County has fought for those same progressive principles–rallying against unjust wars, fighting along with our labor and environmental allies on issues impacting workers' rights and wages and our shared natural environment. We've taken a lead in the Wisconsin Democratic Party to ensure openness for all party members in our decision-making processes.
We support Democrats running for elected office in Dane County and around the state. You can support our efforts by contributing to the party through ActBlue.
The Democratic Party of Dane County has the largest membership of any county party in the state, with membership numbers in the thousands. We have active Young Democrat chapters at the UW-Madison, Madison College, and Edgewood College, with hundreds of students being involved in activities every year.


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NewYorkTimes: Assange Indicted Under Espionage Act, Raising First Amendment Issues
The WikiLeaks founder Julian Assange faces 17 new counts in a superseding indictment over his role in publishing classified documents in 2010.
First Amendment to the United States Constitution Julian Paul Assange
'Curious Eyes Never Run Dry'. The government charged Julian Assange, founder of WikiLeaks, not with publishing classified government information, but with stealing it, skirting — for now — critical First Amendment questions. >>
Assange Indicted Under Espionage Act, Raising First Amendment Issues. The WikiLeaks founder Julian Assange faces 17 new counts in a superseding indictment over his role in publishing classified documents in 2010. >>


Winter Joyful Hearts - ..
Joyful Hearts ministry is designed for individuals with developmental disabilities, providing a quality experience in a safe, Christian environment.
Campers take part in a variety of winter camp activities, but each activity is modified based on the needs of the camper. Activities include games, crafts, Bible Time, faith building activities, and outdoor adventures such as snow tubing and snowman building, as weather and camper health permit.
Our staff and volunteers are trained in working with campers with a variety of disabilities and are committed to ensuring each camper receives personal guidance and assistance as needed. We strive to maintain a one-to-one, or in some cases, two-to-one ratio of campers to staff/volunteers to ensure each camper has the best possible camp experience.
Check out our Summer Joyful Hearts video and camps.
Camp begins with check-in on Sunday from 4:00 to 5:00 pm in the Welcome Center and ends on Friday at 10:30 am.
Payment required to register. Includes housing in the Retreat Center, 14 meals (Sunday Dinner – Friday Breakfast), awesome activities and lots of fun!
Reserve your space now! To register, print and complete the following 3 forms and mail with a check for your payment, or scan and email if you are paying by credit or debit card.
You may cancel until December 5, 2019 and receive a refund, less $50 cancellation fee. After that date, no refunds will be given except in cases of illness or injury (with a doctor's note), less a $200 cancellation fee. If a camper leaves early due to homesickness, disciplinary reasons, or parent request, no refund will be given. All refund requests must be in writing.


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1929–30 Netherlands Football League Championship
30-08-1919 Arsenal 0 Newc. Utd 1
1930 WORLD CUP FINAL: Uruguay 4-2 Argentina
CENTRAL EUROPEAN INTERNATIONAL CUP(BEFORE UEFA EURO) || 1927 - 1960 ||
Dutch Eredivisie League Most Champions 1888-2019
Ireland Wins (1928)
The Netherlands Football League Championship 1929/1930 was contested by 50 teams participating in five divisions. The national champion would be determined by a play-off featuring the winners of the eastern, northern, southern and two western football divisions of the Netherlands. Go Ahead won this year's championship by beating AFC Ajax, Velocitas 1897, Willem II and Blauw-Wit Amsterdam.
HBS-Craeyenhout
Football teams SBV Excelsior
Football teams HFC Haarlem


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Donate through your phone during World's Biggest Coffee Morning
The Macmillan Coffee Morning is an annual event which started in 1990 that sees more than 200,000 people take part, raising £26,914,382 in 2018 alone.
With the growth in cashless transactions and the growing number of people using no or little cash Macmillan want to give supporters the added option of donating via an alternative route to cash at their Coffee Mornings.
While cashless technology is available the challenge was finding a viable and cost-effective route to add this to supporter fundraising kits to be used to host Coffee Mornings run in a variety of locations such as offices, homes, clubs etc without having to invest in expensive contactless systems.
The Sourcing Team working with their technology partner, Thyngs, introduced this cost-effective mechanism that could work within the kits. NFC tags have been added to the existing card collection box which converts the box into a cashless donation point. "The Sourcing Team have been working with Macmillan for over 18 years providing ethical, sustainable and innovative promotional merchandise. Our partnership with Thyngs allows us to bring exciting new technologies that enable low-cost cashless giving to be brought into supporters' homes and places of work.
This innovative technology should help Macmillan build on their hugely successful coffee mornings and open out the cashless giving opportunity to increase overall donations"
– Gill Thorpe, CEO at The Sourcing Team
Hosts register their own Coffee Morning via the NFC tag once their pack arrives. Guests at the event then tap the NFC tag to bring up a donation page on their smartphone to select their donation amount. The platform also allows supporters to add Gift Aid during the transaction increasing the overall donation amount. Once you know, it's easy! Watch Thyngs donation tutorial, here. The mechanism is also supported by an engagement and analytics programme to give full visibility of results by each hosted event in real-time. "We're very excited to be able to test this new technology on our Coffee Morning kits for the first time this year. We simply cannot support the growing number of people with cancer without generous donations from our supporters and this technology will give them an additional way to donate.
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Abby Solomon, Senior Marketing Manager at Macmillan
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Pay scale ( वेतन ) : Rs.38,000 + HRA.
Educational requirements ( शैक्षिक आवश्यकता ) : Ph.D in Life Science.
Experience requirements ( अनुभव ) : At least 2(two)years of post Ph.D research experience in the field of virology with internationally recognized publication record in virology, handling biohazard group-II viruses like dengue and expertise in devising and implementing viral diagnostic techniques etc.
Age limit ( आयु सीमा ) : 37 Years.
How to apply in Indian Institute of Chemical Biology (IICB) ( आवेदन कैसे करे ) : The engagement is purely temporary and, therefore, does not confer any right / claim implicit or explicit for regularization or absorption against any IICB / CSIR post. The age and qualifications will be reckoned as on the date of interview. The upper age limit is relaxable for SC / ST / OBC / PH and women candidates as per rules. Interested candidates fulfilling all the above conditions may appear for the walk-in-interview to be held on 11.05.2018 from 10.30 a.m. to 11.00 a.m.(Reporting time) in the Red Carpet Room with the following documents original and self attested copy - (1) Matriculation Certificate in support of your date of birth, (2) Degree/Diploma Certificate, (3) Original reprints of all testimonials regarding educational qualification, (4) No Objection Certificate from the employer if employed, (5) Ph.D certificate, (6) Experience Certificate, (7)One Passport size photograph.
Detail of Interview: 11/05/2018 Reporting Time:From 10.30 - 11.00 am.
Indian Institute of Chemical Biology (IICB) recruits Research Associate Posts. Candidates with Ph.D experienced can apply.


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The Importance of Treating NYPD Officers as Individuals
On the outrageous murder of two cops and the faction trying to exploit their deaths for political leverage
By Conor Friedersdorf
At 28-years-old, Ismaaiyl Brinsley had been arrested 19 times and served 2 years in prison. On Saturday, in a crime spree that began when he shot an ex-girlfriend in Baltimore, he murdered two New York City policemen as they sat in their car in Brooklyn. "I'm putting wings on pigs today," he wrote in an anti-police Instagram post published prior to the killing. "They take 1 of ours... let's take 2 of theirs." An act of this kind would be totally unjustifiable and worthy of the strongest condemnation even if the victims were abusive police officers who were carefully targeted as payback for some past transgression. In this case, the killer's statement implies that all 34,500 uniformed NYPD officers are interchangeable members of an enemy group rather than distinct individuals whose lives matter. This species of bigoted groupthink is as unacceptable as any other.
Officer Wenjian Liu, 32, was a newlywed who married less than three months ago. His widow is reportedly inconsolable. The New York Times offers a brief bio:
Officer Liu, whose family comes from Taishan, in Guangdong Province, China, attended the College of Staten Island and Kingsborough Community College. He was an auxiliary officer before becoming a police officer in 2007. Bin Fin Liang, 56, said Officer Liu would drop by his restaurant supply shop on the way home from the Police Academy. Mr. Liang asked him why he wanted to be an officer. "I know that being a cop is dangerous but I must do it," Officer Liu replied, his friend said. "If I don't do it and you don't do it, then who is going to do it?"
Officer Rafael Ramos, 40, had worked at the NYPD for three years. "While residents of his working-class neighborhood described the pride he took in being an officer, they remembered him more as the man who shoveled sidewalks after snowstorms, or who took his two boys to nearby Highland Park to play basketball, always with a smile on his face," The Times reported. "Some spoke of his love for the Mets. He bought ham-and-cheese sandwiches at the corner deli, made trips to the laundromat and talked to his boys in Spanish about basketball."
His son was 13 years old.
Early reports suggest that both police officers were well-liked in their communities, though their killings would be tragic and worthy of condemnation in any case. And they are, in fact, being condemned by nearly everyone commenting on the case, which is no surprise: Opposition to the murder of police officers is as close to a consensus belief as exists in American politics, culture and life.
The Sergeants Benevolent Association, a group that claims to represent "approximately 12,000 active and retired sergeants of the NYPD," would have us think otherwise. "The blood of 2 executed police officers is on the hands of Mayor de Blasio," the group declared in a statement that attempted to exploit these murders to advance their political agenda. In a similarly dishonorable statement, "the president of the city's largest police union, Patrick Lynch, blamed Mr. de Blasio for the tragedy. The officers' blood 'starts on the steps of City Hall,' he said, 'in the office of the mayor.'"
And insofar as there is anti-police sentiment in some U.S. subcultures right now, it has little to do with the top-down rhetoric of national political leaders and much to do with grassroots outrage at police killing unarmed people and the proliferation of videos showing police officers abusing their authority, often with impunity. That intense anger over such videos coincides with persistent rarity of politically motivated attacks on cops underscores Radley Balko's observation that "it's possible to both be appalled by senseless executions of cops and angry at unjustified killings by cops." Those positions are not in tension with one another. They are both consistent the with individualist premise that all lives are valuable, as well as the belief that both police and non-police should act lawfully and justly.
In a sensible post at Reason, Nick Gillespie addresses a whole range of attempts to assign responsibility for this killing to someone other than the perpetrator himself:
Just as Sarah Palin's defense of gun rights has zero culpability in the shooting of Rep. Gabby Giffords and Dallas's right-wing "climate of hate" had nothing to do with Marxist-Leninist Lee Harvey Oswald's assassination of JFK, it's worth underscoring at every moment of what is already shaping up as a very ugly debate that the actual killer is the culprit here. As the New York Daily News and other outlets are reporting, the apparent shooter was not only violent and unhinged but had bragged via Instagram that he was "putting wings on pigs" and "putting pigs in a blanket." The distance between such rantings and, even worse, the act of shooting policemen sitting in a patrol car, simply has no relation to legitimate and even impassioned criticism of the militarization of police and the protesting of specific acts of apparent injustice. To suggest otherwise is not simply disgraceful and cheapening to serious public discourse. It's all too often the first refuge of people on the right and the left who are afraid to actually engage in any sort of meaningful debate.
Although I'm in almost complete agreement with that position, I'd add one caveat: While the taboo against violent attacks on police officers is shared by literally every pundit I've come across, literally every elected official who has spoken on this subject, and the overwhelming majority of people who've taken to the streets to protest the killings of Michael Brown and Eric Garner, there are, in fact, documented examples of a tiny minority rejecting that norm, including the folks who took up the chant, "What do we want? Dead cops! When do we want it? Now!"
There's almost no chance that the chants in this unrepresentative protest motivated a killer from a different city to kill cops in New York. The protestors were nevertheless behaving in a disgusting manner and undermining a norm the importance of which has just been underscored by two murdered men and grieving families. An even more disturbing example of this phenomenon, given subsequent events, is the fact that when Brinsley, the cop killer, posted an image of a gun to Instagram with a note about killing police officers, several people "liked" the post. Perhaps they took him to be making a figurative rather than a literal statement, and it's possible some of his followers liked the image of the gun without reading his words. Still, it's disturbing that some seemed to approve of this callous, prejudicial threat of violence. And one can't help but wonder if Brinsley would've thought better of his subsequent actions had his social-media followers objected to his threat or expressed disapproval rather than vague encouragement.
I see nothing wrong with criticizing people who urged or expressed affinity for actual violence against police, even as the bulk of responsibility must belong to the murderer alone. But NYPD defenders are engaged in an attempt to discredit even criticism of police that is totally nonviolent. Theirs is an attempt to squelch legitimate political debate by irrationally associating it with the deeds of a suicidal murderer.
That is scurrilous behavior.
The context is the election of a mayor who is less sycophantic in his relationship to the NYPD than his predecessors, Rudy Giuliani and Michael Bloomberg. Too many police officers are reacting to this duly elected city leader with petulant histrionics that veer uncomfortably close to disdain for civilian, democratic control.
As Doug Mataconis argues at Outside the Beltway, "the fact that the Mayor may have expressed some sympathy for the people who were protesting the Garner decision is neither outrageous nor inappropriate. For one thing, it's worth noting that he is the Mayor of all the people in New York, not just the police officers, and that as the elected leader of the city it is his job, in part, to be responsive to the concerns of civilians who see what they think is an injustice being committed by the police department and the justice system. The argument that being willing to listen to those protesters makes any political leader responsible for the actions of a violent criminal thug who traveled some 200 miles for the express purpose of committing murder is nonsense that ought to be rejected out of hand."
Following an outrageous murder of two policemen who seem to have been good cops, it's emotionally understandable that most people nod along to statements about NYPD officers being "New York's Finest." There are a lot of good cops in New York City. There are, as well, a lot of bad cops in the force of 34,500. People who hate all police officers because some act badly are being prejudiced and irrational. It is also irrational to extol everyone who wears an NYPD uniform despite the fact that some of them abandon whistleblowing colleagues when they need backup, accost an innocent kid with racial slurs and physical threats, retaliate against a fellow officer who exposes systemic misbehavior by trying to have him involuntarily committed to a mental institution, or assault women with pepper spray for no reason. Unions that fight to keep even misbehaving officers from being fired bear some responsibility for the reputation that the NYPD has among its critics, as does every cop that observes misbehavior by colleagues but stays silent. Only by distinguishing among police officers—praising the ones who do their jobs honorably and capably, and disciplining or firing the ones who fall short—can the proposition that the profession is worthy of respect be rationally defended.
At the same time, even bad police officers have an inviolable right to life, and the ones who are murdered are often good cops and valuable parts of communities and families.
The murder of Officers Liu and Ramos is an outrage, a tragedy, and an illustration of why rhetoric urging violence against police officers is wrongheaded and inappropriate. It is also a kind of anti-police attack that is thankfully rare, and in no way diminishes the need for reforms like body cameras, the demilitarization of police departments, training and procedures that emphasize de-escalation and alternatives to deadly force, and employment contracts that prevent arbitrators from reinstating cops fired for incompetence. There are legitimate, albeit wrongheaded, arguments against those reforms, but police shouldn't succeed at short-circuiting the debate by exploiting these awful murders.
May the victims rest in peace.


Looking at the entrance of the familiar door of the house, I was engulfed with fear. I had with me, the result to my Junior Secondary School Certificate Exam (JSSCE). Thoughts of falsifying the result and presenting it to my mum flashed through my mind. My mum's last statement during our last discussion kept playing in my mind. "If you ever bring this kind of result home again, you will see the redness of my eyes, nonsense!" One other thing that made me desirous of changing the result was that after scolding me, she still showed me love by promising me a special gift if I did well in my JSSCE. She didn't stop there as she adviced me to read, study hard, join a discussion group, watch less of Television, play less of games in order to make a good result and also stand out in life. Without a further thought, I turned my back to that familiar door, headed back to school, went to my classroom; because I knew I would be the only one there at that time of the day. Entering one of the empty classes, as I sat to effect the change, right there, something took hold of me. I suddenly had a change of mind. Whatever it was, I didn't know. Could it be conscience? All I knew was that I could not carry the plan through. As I placed my head on the table, the word "honesty" re-echoed severally. Why? Then I remembered it was the last topic that was taught in our civic education before the examination. My teacher defined honesty as the ability to stick to the truth always without compromising. I also remembered it being the title of our pastor's message. My pastor had mice no words in saying those truthful and scary words "A liar is the Devil's son and would also join the devil in hell when he dies in his sins". Then it dawned on me that it wasn't just conscience but the Holy Spirit. At that instance, I made up my mind to go and show my mum the result the way it was. Honesty became the key word.
Releasing me from her embrace, I asked her why she hugged me after failing my exams. Minutes passed by as she explained her reasons. She had actually entered my room one of those days when I was still writing my exams. She found a small piece of paper on the floor with the words ''If I don't pass this exam, I will fake it for my mum'' She had gone ahead of me to check my grades. Though she was unhappy with my poor performance but she was happy that I came out honest about it. Tears rolled down my cheeks. Right there I had a true change of mind and I promised to do all it takes to be the best in the class. She promised to stand by me. Taking advantage of the present joyous mood, I shyly asked "mum do I still have a gift", with that warning look she gave me, I knew I couldn't push the question further. I immediately dropped the idea then thought of the positive ways to be the best in my class so as to get that special gift.


Eagles golfers played the Berea College Mountaineers in the Work College Challenge on Saturday, October 28th. The temperatures were in the 40's with a constant rain. Due to the poor weather conditions, only the doubles matches were played. Because we had 5 on 5, doubles matches had each teams number one player playing one ball against two balls for the other team for two of the matches and one match of two on two. Berea's number one player, Kevin Kim, matched up against Eagles golfers Reece Ison and Aaron Minor. Minor and Ison won the match 2 up. Eagles number one golfer Jared Albright matched up against Mountaineers Ryan Blevens and Dallas Adkins who defeated Albright 7 and 6. Eagles golfers Tyler Davis and Tyler Brewer took on Mountaineers golfers Michael Akard and Blade Hampton, defeating them 3 and 2. Eagles golfers won the event 2 matches to 1 to win the shovel symbolic of the event.


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ManningLive
Jean Griffin Martin Bell
by Robert Joseph Baker | March 10, 2014 10:19 pm
SUMMERTON – Jean Griffin Martin Bell, 79, widow of Jack Ryan Martin Sr. and Dr. James Edward Bell Jr., died Monday, March 10, 2014, at her home in Summerton.
Born Jan. 21, 1935, in Summerton, she was a daughter of the late Ervin Theodore and Marie Wells Griffin. She was a member of Summerton United Methodist Church.
Survivors include a daughter, Jeannie Martin (John) Gasque of Holly Hill; a son, Jack Ryan (Meg) Martin Jr. of Summerton; three sisters, Virginia Ardis and Kenny (Joe) Avin, both of Summerton, and Lynn (Henry) McKinney of Simpsonville; five grandchildren, Allison Gasque (David) Parler of Chapin and Martin Gasque, Guerry Martin, Jack Martin and Davis Martin, all of Summerton; two great-grandchildren, Elli and Grace Parler; four stepchildren, Katharine "Katsy" Bell Ratterree, James Edward Bell III, Anne Middleton "Nancy" Bell and Frederick McDonald "Mac" Bell; and a number of nieces and nephews.
Funeral services will be held 11 a.m. Wednesday at Summerton United Methodist Church with the Rev. Randy Bowers officiating. Burial will follow in Summerton Evergreen Cemetery.
Bill Martin, David Tindal, Roger Flowers, David Ardis, John Senn and George Oxner will serve as pallbearers.
The family will receive friends at the home in Summerton.
Memorials may be made to Summerton United Methodist Church, P.O. Box 35, Summerton, SC 29148; or to the Summerton Evergreen Cemetery Fund, c/o Ellen Ardis, P.O. Box 366, Summerton, SC 29148.
Stephens Funeral Home & Crematory, 304 N. Church St., Manning, is in charge of arrangements, (803) 435-2179. www.stephensfuneralhome.org
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Rihanna Launches New Cosmetics Line "Fenty By Rihanna"
BHR Hollywood Reports...........Rihanna the star will launch Fenty Beauty by Rihanna in fall 2017, partnering with the Kendo beauty division of the luxury goods company, LVMH Moët Hennessy Louis Vuitton, to create her own makeup collection.
According to WWD it's estimated that LVMH's deal may have reached $10 million to secure the line.
This isn't RiRi's first dance in the makeup world. In 2013, she partnered with M.A.C on the limited edition RiRi Hearts M.A.C color cosmetics collection.
In 2014, she worked with Viva Glam for AIDS research fundraising. In the past, Kendo has worked with celebrities and brands including Kat Von D and Marc Jacobs.
Rihanna has other deals, of course. Puma's creative director recently announced her $80 "Fur Slides by FENTY," which will be available for purchase on April 22. Meanwhile, she continues to tour the globe on her "ANTI World Tour," which is set to stop in Toronto this evening.


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Why Is The NCAA Downsizing?
Steve Seepersaud
Question: How many Division I college football national championships has Jim Tressel won as a head coach?
(You can find the answer at the end of this article.)
The 2002 football season was incredibly profitable for The Ohio State University. When the Buckeyes scored an invite to the national championship game, the school took home a payout of more than $10 million US. A win over Miami in the Fiesta Bowl meant more money coming in, as Ohio State profited from national championship gear such as hats and shirts.
Making it to a game that's part of the Bowl Championship Series (BCS) means mucho dinero . But if a school hasn't been to a BCS game or doesn't have a football team, it adopts a lesson from Business 101: downsizing.
small guys suffer
The college sports gravy train has clearly skipped stops like Vestal, New York, home of Binghamton University. It's a medium-sized state school that made the jump to NCAA's Division I several years ago. Division I status and a slot in the America East Conference mean more money and exposure for the university's basketball teams.
But it hasn't helped the wrestling team, which will disappear in spring 2004. Administrators recently decided that $160,000 a year was too high a price tag to keep the team going.
"We simply do not have a sufficient base of wrestling alumni to raise the substantial funds that would be needed to sustain the program, even for the near term," school officials said in a statement.
Administrators said they preferred cutting an entire team to slashing budgets of all the university's teams.
crumbling empire
Binghamton isn't the only school feeling the financial pinch. And it doesn't have to look too far to find others who are suffering. New York State has less money to dole out to its colleges. The attacks on the World Trade Center cost the state billions of dollars. Budget deliberations have been painful as Empire State lawmakers have tried to cut to the bone wherever possible.
Like Binghamton, the State University at Albany is a recent convert to Division I and a member of the America East. Albany was forced to cut six programs from its athletic department. The State University at Plattsburgh cut four teams. The College at New Paltz could no longer afford to fund seven of its programs.
Sure, many fans across the country don't know or care about schools like Plattsburgh or New Paltz. You won't see them in BCS bowls or the NCAA basketball tournaments. However, the true impact is that hundreds of athletes will be denied the opportunity to represent their schools on the field while earning college degrees.
Guys playing football bring in all the cash, but women get equal amounts of money for sports...
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Ενημερωτικό Δελτίο 229 - Μάρτιος 2017
MARCH 2017 - TOPICS
13th Hel.A.S. Conference
IAU Junior Membership
The Society would like to congratulate Ordinary Member Dr. Christina Plainaki, until recently a PostDoctoral researcher at IAPS-INAF, Rome, for accepting a Researcher position at the Italian Space Agency (ASI). Dr. Plainaki can be reached at her new e-mail address, christina.plainaki[at]asi.it . The Society extends its best wishes to Dr. Plainaki for every success in her future endeavors.
The Society would like to congratulate Junior Member Mr. Ioannis Liodakis, currently a PhD student at the University of Crete, for being awarded an Institute Postdoctoral Fellowship by the Kavli Institute for Particle Astrophysics and Cosmology (KIPAC) at Stanford. Mr. Liodakis will be moving to KIPAC in September this year, upon completion of his Thesis.
The Society would like to congratulate Ordinary Member Dr. Maria Petropoulou, currently a PostDoctoral researcher at Purdue University, for being awarded a prestigious Lyman Spitzer PostDoctoral Fellowship at Princeton University. Dr. Petropoulou was the recipient of the Hel.A.S. Best PhD prize in the Society's 12th Conference (Thessaloniki, 2015). Dr. Petropoulou will be moving to Princeton later this Year.
The Society would like to congratulate Ordinary Member Dr. Christos Efthymiopoulos for a honorary distinction presented to him by the IAU Minor Planet Center. In its January 12, 2017 meeting, the Center named the minor planet "2002 PV34" "Efthymiopoulos", in recognition of Dr. Eftymiopoulos' contributions to the field of Celestial Mechanics. "Efthymiopoulos" (2002 PV34), has been discovered on August 5, 2002 by CINEOS at Campo Imperatore.
2. Hel.A.S. 13th Conference
Registration is now open for the 13th Conference of the Hellenic Astronomical Society (website: http://www.helas.gr/conf/2017/), to take place in Heraklion on July 2 - 6, 2017. We encourage Society members planning to attend the conference to register as soon as possible. Please keep in mind that hotel availability may be very limited in Heraklion in early July, so it is important for participants to make accommodation arrangements well in advance.
The conference venue will be the Cultural and Conference Center of the Municipality of Heraklion, conveniently located near the downtown area, next to the Kommeno Benteni gate of the Venetians Walls. The venue is at walking distance from Heraklion city center and, as long as accommodation is booked early, participants have a wide variety of conveniently located hotels to choose from (an indicative list would include hotels Kastro, Atrion, Lato, Iraklion, Capsis Astoria, El Greco, Megaron, Olympic). Early booking using online booking tools allows for a variety of hotel options, good deals on hotel prices, and the possibility of free-of-charge cancellation.
3. IAU Junior Membership
The Executive Committee of the International Astronomical Union (IAU) proposes to create a new category of membership, the "IAU Junior Member". This new category is expected to be open to PhD Students and/or early-career PostDoctoral researchers in the area of Astronomy and Astrophysics. This proposal, with details still to be shaped, was based on the results of a relevant questionnaire, publicized in February 2017, in which 89% of respondents voted favorably to the IAU instituting this new membership category.
The establishment of IAU Junior Members will require an amendment in the Union's Statutes that must be approved by the IAU General Assembly. The next, XXX General Assembly, will take place in Vienna, Austria, in August 2018. Months ahead, the IAU Executive Committee will gauge the opinion of National Members with respect to the content of the proposal, that will outline the specifics of the new IAU membership category.
The Society will follow the developments and keep its Members informed, as there may well be opportunities for Society Members to become IAU Junior Members.
The following openings have come to our attention for this month:
European Social Fund. The Society notifies its Members that the proposal submission deadline in the framework of the European Social Fund (ΕΣΠΑ), organized by the General Secretariat of Research and Technology (GSRT), has been shifted to March 15, 2017. Interested proposers are advised to consult their institutional research organization structures (ΕΛΚΕ). More information on this Call is available here.
Hellenic Foundation for Research and Innovation. The Call for basic research at postdoctoral level, organized by the newly established Hellenic Foundation for Research and Innovation (HFRI - Ελ.Ιδ.Ε.Κ.), is still open. Proposals must be submitted electronically by 17:00 on March 31, 2017. More information about this call and proposal preparation can be found here.
PASIPHAE Collaboration. The PASIPHAE Collaboration (http://pasiphae.science) is looking to fill a fully funded, 3-year PhD position on experimental polarimetry for astronomical applications. The selected candidate will be enrolled at the PhD program of the Physics Department of the University of Crete and will also spend considerable time at the Inter-University Center for Astronomy and Astrophysics in Pune, India. More information about this opportunity can be found here.
Postdoctoral position on Structural and Thermal Models of Rocky Planets and Solid Exoplanets, Berlin, Germany, National Aeronautics and Space Research Centre (DLR). This vacancy is part of a new DFG Research Unit focusing on the development on realistic rocky planet and exoplanet models in collaboration with experimental and theoretical research groups studying matter under extreme conditions. More information can be found here.
This Newsletter was sent to all members of Hel.A.S. who have e-mail access. The next edition of the Newsletter will be mailed around April 1st, 2017. Please send your announcements (e.g., appointments/departures, job openings, research opportunities, awards, conferences in Greece) or comments before March 25, 2017. If you do not wish to receive future issues of this Newsletter or the e-mail address to which it was sent is not your preferred one, please inform the Secretary of Hel.A.S. at secretary@helas.gr.


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The Trick's Retreat is located in Cherry Grove, North Myrtle Beach, SC and is 2 blocks from the beach!
Our home has 2 bedrooms and 2 bathrooms. The master bedroom has 1 queen, the guest bedroom has 2 queens, and we also have a sleeper sofa in the living room.
The Trick's Retreat is an elevated home with parking space underneath the house, enclosed outdoor showers, and a bbq grill upstairs on the deck. On those lazy mornings you can enjoy brunch in the Carolina room where we have a 4 seat table and a chaise where you can sit and enjoy a beautiful sunny morning.
We have a book shelf with books you can take to the beach as well as boardgames and cards for entertainment. Basic broadcast, SlingTV, and high speed WiFi are also included.
We have a washer and a dryer. Dishwasher soap and a starter set of laundry detergent are provided, as well as a starter set of soap and shampoo/conditioner per bathroom. Bath towels and linens are provided with the Departure cleaning fee but please bring your own beach towels.
Though a fireplace is present, the propane is not connected.
If you're interested in booking, we require a signed contract and a copy of your driver's license to verify identity prior to booking a reservation. The rental rules and other information are listed in the rental contract. We look forward to hearing from you!
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Jim Gray
James P. Gray has been a trial judge in Orange County, California since 1983. Before becoming a judge, he served as a Volunteer in the Peace Corps in Costa Rica, a staff judge advocate and criminal defense attorney in the Navy JAG Corps, a federal prosecutor in Los Angeles, and a civil litigation attorney in a private law firm, in addition to being a Republican candidate for US Congress in 1998, and a Libertarian candidate for US Senate in 2004.
Judge Gray has discussed issues of drug policy on more than two hundred television and radio shows and public forums all across the country. Using his experience on the bench and elsewhere, he has also authored a book on the failed War on Drugs as well as Wearing The Robe, about practical and ethical issues in being a judge.
Past Shows:
James P. Gray has been a trial judge in Orange County, California since 1983 and was the 2012 Libertarian candidate for Vice President. In the first half, he discussed how the Libertarian Party has been surging in polls this year, and his views on drug policy reform, Social Security, taxes, and immigration.
In the latter… More »
Host: George Noory
James P. Gray has been a trial judge in Orange County, California since 1983 and was the 2012 Libertarian candidate for Vice President. He discussed many of the issues ignored by mainstream politicians including drug legalization, education reform, a flat tax system, unnecessary wars, and losses of freedoms and privacy.
… More »
Saturday April 20, 2013
In the first half of the show, John B. Wells was joined by Judge Jim Gray for a discussion on the issue of marijuana and drug prohibition laws in the United States.
In the latter half of the program, author Doug Fine talked about legal cannabis farming and how it… More »
Host: John B. Wells
George Knapp welcomed Judge Jim Gray for a discussion on the possibility of reforming America's drug laws, taking illegal drug usage from a criminal issue into a social and medical one. "Drug prohibition is the biggest failed policy in the history of our country, second only to slavery," he declared.
More » Host: George Knapp