I created the following charts a long time ago for my girlfriend (now my wife) who wanted some animated charts for an Excel presentation at work. Not long after we had a request to display data in a chart which moves on a periodic basis. This can be very useful especially if you want to show data aligned with rolling forecasts. Displaying the last 12 months in a given period need not be as manual as changing all of the charts every month or quarter to update the chart for the last n periods.
The way it is done is with dynamic ranges and a small amount of VBA. I am sure this could be done without VBA and I may get round to replicating this without code one day. As you move the Spinner Button (the object with the arrows at the bottom of the screen) to the right , the charts will increment in steps of one month. The chart can also decrement ( go back in time ) by clicking on the spinner button control on the left. I only have 17 months data in the data table above but you could include as many months as you wish.
The Static Ranges which are controlled by VBA are originally titled.
I have used the x to prefix the named ranges to show that these are the labels which are referred to in the Chart.
The following will control the whole process calling the Increase or Decrease routine each time the spinner Button is clicked.
The following procedure is the Excel VBA for increase the amount of series shown in a chart. This is for the manual animation where a button is pressed to trigger chart movement.
The following procedure is the Excel VBA for decreasing the amount of series shown in a chart. This is for the manual animation where a button is pressed to trigger chart movement.
The animation process itself on entry can not be achieved without the Assistance of VBA. There needs to be a trigger to change the cell value so the chart moves. The following Excel VBA procedure will run every one second.
Sub Animate() 'Excel VBA to annimate, process runs 1 second apart for 12 seconds.
For i=1 To 12 'Loop for the 12 months in 12 seconds.
The following will reset the page to its original position.
The following sets the chart off when the workbook opens.
Private Sub Workbook_Open() 'Excel VBA on open event for animation.
The following file shows a practical example of the animated charts moving which contains all of the above Excel VBA procedures. The macros should be adaptable to just about any Excel file type.


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Early post-operative complications in abdominal surgery at the university clinics of Lubumbashi: Frequency, diagnosis and prognosis
Author(s): Augustin Kibonge Mukakala, David Mutombo Mwembo, Iteke Féfé Rivain, Serge Ngoie Yumba, Tresor Kibangula Kasanga, Stephane Ilunga Mukakangala, Eric Wakunga Unen, Catherine Saleh Ugumba and Willy Arung Kalau
Abstract: Introduction: Postoperative complications in abdominal surgery have a high incidence in developing countries' hospitals, thus increasing the rate of their morbimortality. The aim of this work was to determine the frequency of early postoperative complications in abdominal surgery, their indications for operation, the types of postoperative complications, and their prognosis at University Clinics of Lubumbashi.
Patients and Methods: This is a descriptive cross-sectional observational study with retrospective data collection from January 1, 2018 to December 31, 2019 including all patients operated on in the abdominal surgery department of the University Clinics of Lubumbashi and having presented complications within 30 postoperative days.
Results: The frequency of early postoperative complicationsin abdominal surgery was 32.2%. The sex ratio M / F was 2.5 and the mean age was 31.5 ± 0.6. Emergency was the mode of admission in 80% of cases with a mean admission time of 17.2 ± 0.5. In this study, 71.42% of patients were classified ASA III. The mean time to surgical management was 36.5 ± 1.7 hours.Asthenia (62.9%) and abdominal pain (80%) were the most dominant functional signs. Suppuration of the wound (30.5%), abdominal distension (26.6%) and flow of stercoral fluid through the wall (23.8%) were the most dominant physical signs. The antibiogram on wound secretion (19%), imaging combining the chest x-ray (20%), the abdomen without preparation (27.6%) and the abdominal ultrasound (65.7%) are additional examinations which were more practiced. The post-operative complications were grade III in 95.24% of cases (n = 100) according to the Clavien-Dindo classification. The initial indications for surgery were more dominated by acute peritonitis (60%), followed by mechanical intestinal obstruction (16%). The duration of surgery was> 2 hours in 81% of cases and in 58.09% of cases the initial intervention was performed by a specialist. The mean time to resumption of oral feeding was 3.4 ± 0.6 days (Extreme: 12 hours and 192 hours). POC occurred within 5 days of surgery (59.04%).
Surgical complications were more dominant (80%), made up of postoperative peritonitis (33.33%), digestive fistulas (19.5%), surgical site infection (16.7%), post-operative intestinal obstruction (13.1%) and evisceration in 6%% of cases. The majority of post-operative complications (52.4%) had undergone relaparotomy, and the outcome was good in 69.5% of cases (n = 73/105), with a mortality rate of 30.4% of cases (n = 32/105). The mean length of hospital stay was 27.4 ± 0.5 days.
Conclusion: Postoperative complications are frequent at University Clinics of Lubumbashi and dominated by infection, postoperative peritonitis and digestive fistulas. The implementation of well-coded management algorithms could reduce this incidence.
Augustin Kibonge Mukakala, David Mutombo Mwembo, Iteke Féfé Rivain, Serge Ngoie Yumba, Tresor Kibangula Kasanga, Stephane Ilunga Mukakangala, Eric Wakunga Unen, Catherine Saleh Ugumba, Willy Arung Kalau. Early post-operative complications in abdominal surgery at the university clinics of Lubumbashi: Frequency, diagnosis and prognosis. Int J Surg Sci 2021;5(1):136-142. DOI: https://doi.org/10.33545/surgery.2021.v5.i1c.601

redpajama_set_name: RedPajamaCommonCrawl


The free scrap car collection service in Beacon's Bottom (HP14), Buckinghamshire. Old scrap cars, if on the road will still need to be taxed, even if you are not using the vehicle, this is the law. Do not pay a company to collect your scrap car. We can collect your vehicle free of charge in Beacon's Bottom!
As well as offering a completely free collection, we are also currently able to offer cash for scrap cars in Beacon's Bottom depending upon the weight of the vehicle!
We have a huge amount of happy customers in and around Beacon's Bottom as we have been covering the Buckinghamshire area for quite some time now. We know the local area so when you need us we will be there in no time at all. Scrap Car Beacon's Bottom prides ourselves on offering a prompt and reliable service and being there with you at the agreed time slot. We are able to collect vehicles day or night, seven days a week, even on bank holidays, and we will work round you.
We take care to ensure that your vehicle is disposed of in the right way. There are a few companies out there that will sell your scrap car as a runner and not scrap it, quite often they will not even inform the DVLA that the vehicle has a new owner. This can result and usually does in you being fined. Unlike these companies we always ensure that the DVLA are notified that your vehicle has in fact been scrapped, giving you complete peace of mind in Beacon's Bottom. Any car that we scrap we ensure that it is scrapped in the most environmentally friendly way possible, we like to do our bit.
Please ensure that your car is disposed of in the right way, we would like to keep the streets of Buckinghamshire clean. Broken down cars on streets makes our area very untidy and run down, scrap your old banger today and make your street and your neighbours happy. Scrap that car free, call an advisor today!
It couldn't be simpler to scrap your old vehicle in Beacon's Bottom. Just by picking up the phone you can learn the process from our helpful phone operators. Rather than calling if you would like to find out about our services please feel free to look at the guide on scrapping your car.


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White is another possibility of this chevron nursery bedding to pick out. White is just a great shade for the bedding wall shade. You may believe or not. It provides a clean and fresh living feeling. Moreover, it's giving a relaxing and soft feeling. The exposure of sunlight may make it seem exactly the bedding look more spacious. You may possibly have traditional accents on your bedding. It looks great with whitened since teal chevron bedding. It will not matter which pattern you simply want in which white will probably be always acceptable for any patterns and accents. It reveals and deflects the light nicely.
Possessing a teal chevron bedding could be magnificent. That is only because the white colour is an easy yet tasteful colour therefore you are able to experiment it with the decorations or shades. A white bedding place can also create an even far more relaxing setting as the colour is neutral and calming, therefore it is a safe selection for anybody who doesn't possess some knowledge about bedding design. Naturally, there are a number of tips in selecting a chevron sheets so your bedding will appear amazing as well as comfortable.
Bedding can be just a individual position that possibly reaches your very last resort of escapism. Ofcourse you would like to unwind and rest comfortably inside after a long demanding moment. This really is the reason arranging the teal chevron bedding can be very significant. As a way to make a teal crib bedding, you need to get a really good huge image of it. Would you like it to be more huge and uncomplicated, or luxury and elegant? Go pick the one that suit your own style, and that means you may feel dwelling in your private space.
There are lots of people who would like to play with it secure and also want to decorate their own bedding to more customary styles or you might understand as the modern fashion. Subsequently teal chevron bedding is something that might be overly tough or insecure to allow them to pull off. Howeveryou should realize that chevron sheets is flexible and more versatile when you think, The austere feeling can make your bedding more comfortable and inviting as good. It transforms a room to some more comfortable area together side the classic beauty or attracts the lovely nature inside your bedding.
It also occurs in the teal crib bedding. Many of the girls really like to have a cute and nice rug within their bedding. With this sort of teal chevron beddingthey may spend the majority of their time on the carpet. Discussing together with their friend, playing and relaxing really are all done about the carpet. Maybe not just for relaxing and playing, but the rug within her bedding may become the location because of her enormous and fluffy dolls. Besides that, it is possible to stop your infant out of using a nasty drop when she is sleeping because the carpet will soon safeguard her head.


BOOHER is the new project from Michael Booher, former singer and main songwriter for Austin's beloved Zykos. With the new band, Michael is building on his previous songwriting strengths, crafting diverse rock n' roll songs, focused on vivid lyrics and contagious melodies.
Old Flame Records discovered BOOHER during SXSW 2016 and fell in love with the band's energetic rock sound. During the summer BOOHER announced they had signed a record contact with Old Flame and would be releasing their debut LP, Funny Tears, in 2017. We're excited to announce that the official release date is January 27, 2017.
Funny Tears was produced by Mike McCarthy (Spoon, Heartless Bastards) and mastered by Alex Lyon at The Bubble. The album features a hit squad of some of Austin's (and beyond) finest musicians including Cully Symington (Cursive, Afghan Whigs) on drums, Will Sheff (Okkervil River) on vocals, Michael Kingcaid (What Made Milwaukee Famous) on vocals, Matt Roth on bass, Doug Walseth on guitar & pedal steel, Ben Lance (Broken Gold, A. Sinclair) on guitar, Mike St Clair (White Denim, Polyphonic Spree) on horns, synth and strings, Ben Houtman (The Gloria Record) on keyboards, marimba and organ, Adoniram Lipton (Slowtrain) on keyboards, organ and piano, Brendan Bond (A. Sinclair, Matthew Logan Vasquez) on vocals, and Aaron Sinclair (A. Sinclair) on vocals.
BOOHER will be returning to perform at the 2017 SXSW Music Festival, March 13-19, in Austin, Texas. Register to attend SXSW 2017 today!
The post BOOHER Announces Debut Record Following Signing at SXSW appeared first on SXSW.


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Our Guide to The Top Goal Scoring Midfielders
The Premier League has never been in short supply of goal scoring midfielders. Most strikers hang up their boots without reaching 100 goals in the Premier League, so you know you have a special player in your midst when a midfielder approaches or even exceeds that milestone.
The midfield position features a variety of different roles that can spark endless debate about what makes a perfect player. But whether they're an attacking central player, a midfield maestro or a deadly winger, the goal scoring midfielder is always a favourite with fans, managers and teammates alike.
What Makes a Goal Scoring Midfielder?
The short answer is not surprisingly: goals.
That's the price of entry to this sought-after club, but the top goal scoring midfielders do come in a few different forms. Super Frank Lampard is probably the first man that springs to mind. The Chelsea legend is the Premier League's 4th highest goal scorer of all time, with an astounding 177 goals. That's more than the likes of Thierry Henry, Robbie Fowler, Teddy Sheringham and Man City's all-time top scorer Sergio Aguero.
Lampard could turn a ball into a goal-seeking missile from range, and his ability to read the game and make clever runs into the area were key to his prolific success. His arch-rival Steven Gerrard also broke the 100 goal mark in the Premier League, with long-range net-busters. These two were box-to-box midfielders, heralded by many as the greatest two English midfielders of their generation.
Manchester duo Paul Scholes and Ryan Giggs managed 109 and 107 in the Premier League, respectively. Scholes could hit a tree from 250 yards away and his ability to spread the play became a fundamental aspect of United's style of play. His genius was admired by some of football's modern greats and it was his ability to score from 30-yards, seemingly whenever he felt like it, that made him one of the best goalscoring midfielders of his era. Giggs' mazy runs and lightning-quick pace was key to his goal scoring success - beating defenders and cutting in from the wing to strike the ball home.
Who's the Current Top Scoring Midfielder?
The Premier League's top scoring midfielder in 2017/18 is Raheem Sterling. Man City have been formidable in front of goal and look set to break all sorts of goal scoring records this season. Teammates Sergio Aguero and Gabriel Jesus have scored nine and eight goals respectively from up top, while Sterling also has nine from midfield. Not far behind him is Leroy Sané on six.
Watford's Abdoulaye Doucouré follows on five with Kevin De Bruyne just behind on four. The chasing pack, all on three, includes Dele Alli, Eden Hazard and Paul Pogba.
Which Midfielder Scored the Most Goals Last Season?
The top goal scoring midfielder in 2016/17 was Dele Alli with a very impressive 18. His Spurs' teammate Son Heung-Min was just behind on 14, while Eden Hazard separated the two with 16 goals to his name. Liverpool's Brazilian magician Philippe Coutinho bagged 13.
Which Midfielder has Scored the Most Goals in Premier League Football?
Frank Lampard's record of 177 Premier League goals is unlikely to be beaten any time soon.
Steven Gerrard is the man with the second highest goals from midfield. Liverpool's star man over a 17 year career bagged 120 goals in 504 appearances.
Ryan Giggs was still playing at the top level at 40 years old, and the Welshman won 13 Premier League titles over the course of 20 seasons, scoring 109 goals in the process.
Paul Scholes is quite possibly your favourite player's favourite player, and it's clear to see why as the ginger ninja hit the back of the net 109 times in the Premier League.
Matt Le Tissier completes the exclusive club of midfielders who reached 100 goals in the PL. The Southampton star had a serious lack of pace or stamina, but more than made up for it with his technique, intelligence and goal scoring ability. He scored 100 exactly.
Our Best Midfielder Goals
David Beckham was the undisputed king of free kicks at Manchester United, but his successor in the number 7 shirt scored a goal that changed the way we would view free-kicks forever. Cristiano Ronaldo scored the original 'knuckleball' against Portsmouth in 2008, smashing the ball with ferocious pace, but with topspin so that it quickly dipped and flew past a helpless goalkeeper into the top corner.
Four touches of pure football genius against Newcastle in October 1993. A backheeled volley to flick the ball over his own head, a couple of perfectly timed lobs to beat two defenders, and an inch-perfect side-foot into the bottom right-hand corner. Matt Le Tissier's greatest ever football creation? We think so.
By no means was this Frank Lampard's most important goal, but it surely is one of the finest examples of the nonchalant way he used to ripple the back of the net from 30 yards. Take a bow Frank.
Our midfielder goal scoring predictions.
This season we expect the Man City duo of Sané and Sterling to run away with the top two spots as Pep's side continue to thrive in front of goal. They have the best supply of any other midfielders in the league and the early signs suggest they will be in rampant form all season, providing they can avoid injury.
If Dele Alli can find that magic touch we saw on so many occasions last season he's likely to make his way well into double figures, while Hazard and De Bruyne are also expected to reach the 10-goal mark. Watford's Doucouré is the surprise package this season, but don't count him out of keeping pace with the usual suspects.
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2018 Sierra Poetry Festival: Second annual festival returns to Nevada County
Entertainment | April 25, 2018
Michael Rohm
Special to Prospector
Dream a Difference unites small schools around the world using poetry as a bridge. This year, Twin Ridges School District has partnered with students in Bangladesh and Uganda, the latter of whom have filmed a video of greeting that will screened at the 2018 Sierra Poetry Festival.
Courtesy of Nevada County Arts Council
KNOW & GO
WHAT: 2018 Sierra Poetry Fesitival
WHEN: 8:30 a.m. to 5 p.m. Saturday with a wrap party beginning at 5:30 p.m.
WHERE: Sierra College in Grass Valley and The Stone House restaurant in Nevada City
TICKETS: Free for youth 18 and under. For all else, $25 for featured readings only; $45 for the full pass, including workshops and readings.
INFO: For more information call 530-278-5155, email questions to info@nevadacountyarts.org, or go online to https://www.nevadacountyarts.org/festival-program
The muse is a fickle master. It comes with a sigh or a storm, with a pen or a pistol. Often it doesn't come at all.
Though a writer never really knows when to expect a creative visitation, few places are more likely to summon the muse than the 2018 Sierra Poetry Festival, an event that brings together poets and those who love poetry.
The second annual poetry festival follows in the footsteps of the inaugural event last year, where community members both young and old gathered at Sierra College in Grass Valley to celebrate the artistic achievements of some of California's brightest poetic lights.
According to Eliza Tudor, Executive Director of the Nevada County Arts Council, the success of the 2017 festival helped to pave the way for 2018.
"Our aim was to create an annual event for the whole community," Tudor said. "We have a fabulously literary community [in Nevada County] but they don't necessarily connect in an anchored way. We wanted to bring everyone together once a year in a way that could be aspirational and inspirational."
"Last year was incredible," she added. "Our inaugural Sierra Poetry Festival was a watershed moment for poetry in Northern California."
Establishing an annual tradition
On Saturday, April 28, Nevada County will again get a chance to prove it's outsized appetite for the arts. From 8 a.m. to 5:30 p.m., attendees will experience a full day of creativity from those who do it best.
At the fore of the artistic roster is Robin Coste Lewis: Poet Laurate of Las Angeles, winner of the National Book Award for Poetry, and the 2018 Sierra Poetry Festival keynote speaker.
Also performing this year are Kim Shuck, Poet Laurate of San Francisco, and Indigo Moor, Poet Laurate of Sacramento.
These luminaries are the vanguard to an event that hosts nearly 20 authors with dozens of published books and countless poems among them.
"The talent and diversity of these poets is extraordinary," Tudor said of the 2018 lineup. "Our programming is interdisciplinary — combining poetic cinema, video poetics, the spoken word, performance poetry, song-writing and music."
In addition to performances and readings, the festival programming also includes a number of workshops led by some of the poets themselves. Topics include "The Art of Noticing," "Video Poetics," "Igniting Your Poetic Fire," and a special workshop with Poet Laurate of Sacramento Indigo Moor, "Writing to History and Culture."
Youth & poetry
The 2018 festival is not a mere continuation of the inaugural event last year. While it advances a program similar to that of 2017 — readings, workshops, and creative mingling — the festival this year also introduces new components.
"An aspect of cultural equity is diversity and inclusion," Tudor said. "We want to encourage, educate, and inspire fledgling writers of all ages to become a part of a new and dynamic poetry scene as part of a broader effort to create age-diverse participation, particularly in youth."
While the emphasis on youth was strong last year — according to Tudor, the audience doubled in size during Poetry Out Loud, the youth recitation part of the program — this year it will be featured more prominently.
In addition to supporting and participating in Poetry Out Loud, a national program that incorporates poetry into the classroom, Nevada County Arts Council has also partnered with Twin Ridges School District to join Dream A Difference, an international poetry project that connects small schools around the globe.
This unique partnership makes Washington and Grizzly Hill schools the first and only two schools in the United States to participate in Dream A Difference. Components of the project include sharing poetry with students in Bangladesh and Uganda.
"The exposure this gives our kids is extraordinary," said Tudor. "It teaches empathy like nothing else."
The result of this partnership will be on display Saturday as a featured, albeit deliberately unannounced, capstone of the poetry festival.
"Some of the kids in Uganda have sent us a video of themselves dancing for our kids in Nevada County Schools," Tudor said. "It's so beautiful. It's all about teaching empathy awareness."
"We're growing a generation of poets," Tudor added. "We'll be seeing the outcomes of this reach fruition years from now."
Attending the festival
The festival will conclude with a wrap party beginning at 5:30 p.m. at The Stone House in Nevada City. The party will include a chance to meet the poets and fellow festival-goers over drinks and a small bites menu.
For information about tickets, directions, and scheduling, visit https://www.nevadacountyarts.org/festival-program
And if you attend, be sure to take a notepad and a pencil. The muse just might strike.
Michael Rohm is a freelance writer. He can be reached at mirohm13@gmail.com.
Toots and the Maytals take Grass Valley: 'Father of reggae' draws crowd at California WorldFest
Library fun at Pioneer Park: Library to "Pop Up" at county locations
Reinette Senum's 'Alaska Revisited' returns to Nevada City
Glory Singers Concert & Hymn Sing in Grass Valley
J.S. Bach meets Nevada County composers for lunch


The hotel is located at the corner of Seymour and Hastings Streets, and is one of the newest hotels to grace the downtown skyline. The newly opened fitness center, located on the fourth floor, offers state of the art cardio equipment, yoga room, flat screen TV and more. NOTE: Effective April 1, 2008 the property will be completely NON-SMOKING. The hotel will no longer offer designated smoking suites and all of the public areas will continue to be NON-SMOKING. (0908/KC)The Delta Ssuites have either one queen bed or two double beds. Other amenities include desk, high-speed Internet access (fee apply),cable/satellite TV with pay per view movies, clock radio, coffee and tea maker and minibar, refrigerator and microwave on request, hair dryer, iron and ironing board.The Delta Ssuites have either one queen bed or two double beds. Other amenities include desk, high-speed Internet access (fee apply),cable/satellite TV with pay per view movies, clock radio, coffee and tea maker and minibar, refrigerator and microwave on request, hair dryer, iron and ironing board.Property is located in downtown Vancouver's waterfront district, ideally situated for shopping, nightlife and easy access to local tourist attraction and activities. Only a few minutes walk to the Vancouver Trade & Convention Centre, waterfront, Canada Place, theatres, shopping, Gastown and GM Place.There is a restaurant in the hotel, and a lounge in the lobby for cocktail and snacks. There are a variety of restaurants within walking distance.A 23-story building.The lobby is medium size.
The preferred airport for Delta Vancouver Suites Hotel is Vancouver, BC (YVR Vancouver Intl.) 11 km / 6.9 mi.


Apple on Tuesday afternoon began informing a select group of developers that it plans at least one more maintenance update to its Mac OS X 10.4 Tiger operating system ahead of October's planned release of Mac OS X 10.5 Leopard. Since developers have yet to received the first pre-release seeds of the software update, details outside of the version numbering – Mac OS X 10.4.11 – are few and far between.
Boh Engadget and AppleInsider reports that Apple will host a special event August 7 and it relates only to new Mac products. Sweet!
I better warn my credit card company in advanced.
it's nice to see that apple cares about his customers (not like microsoft: two service packs in 6 years).
As a customer having waited 8 weeks for a new MacBook Pro, with still no computer in sight, I'd say that they could care quite a bit more about their customers.
Good to see that they'll push out another update before Leopart, though.
True – but it could ne a bad sign – backwards compatibility for some applications is being dropped – hence the need to support it longer than required. So it could be a double edge sword.
Tell that to the people still waiting for their orders or RMA claims.
Tell that to the people waiting for their 5th / 9th xbox replacement. Or to people waiting for Dell.
Im not excusing apple but when you process thousands/millions of computers and other CE your bound to get slip ups.
Personally i am very happy with Apple's level of service, which i also think a large majority are.
Although getting back up topic, i would say the biggest update im waiting for is leopard but it's nice to see Apple keeping up with maintaince for their current release and not push it to the side lines.
Yah, you didn't know that Apple writes buggy software and has to quarterly upgrade just to keep 5% market? But MicroShaft offers bug free on delivery and the 'service packs' offered every 1-2 years are really just more goodness to debug for them.. Almost a means to keep their slopware developers employed during ice age release cycles.
I actually look forward to a OS X update. I'll be looking forward to a new version of OS X.
New Hardware on the way.
And if you are tired of waiting for RMA claims and don't mind getting a little dirty, OSx86 is still an option. Just make sure your computer has the drivers for it.
Mine works 100%, and I even bought a copy of tiger just to support Apple.
You're comparing OSx86 to a new Mac? Sorry bud, they don't compare. People who do have Mac hardware know hardware-software relation is the key. I've got a Mac Mini and a MacBook Pro and I would consider it repulsive to try run OS X on a standard PC, you'd lose everything that makes a Mac better than a PC to begin with.
Apart from the BIOS/Firmware what do you see different inside your Mac.
Google should provide a tutorial on how to remove the case cover, brace yourself!
apple also just released security updates for the iphone, safari 3 and osx panther & tiger.
…is the last funny thing abuot the apple switch.
well, in the end, will tiger exit from beta status?
By that reasoning Windows XP is still in Beta, and Vista will be too for all eternity.
maybe, but actually, i don' t care: in fact my powermac has only os x, so i comment abuot this.
10.4.10 broke more than it fixed for me. First time an update caused me grief, but theres a whole grumbling list about the issues in 10.4.10 on Apples site. I've had a firewire audio bug open since 22nd June… lets hope this fixes it!
You simply don't get the same user experience with a Generic PC that you get with Apple Hardware.
You can't install updates without waiting for them to be checked and possibly patched. Especially OS point releases.
Some Apps might not run correctly. Depending on your choice of hardware you might not have sound, or wireless, or bluetooth.
I think it's fun to run it as a "Proof of Concept" and for playing. But, I wouldn't use a Generic PC with one of the Cracked MacOS X releases as a daily driver.
The instability, and the inability to update normally just doesn't work for me.
If it were more transparent, and just like using Apple Hardware it would be a different story.
Strange, it sounds like you have never ran it.
The ONLY time I can't install updates is the system updates, and right now I am using 10.4.10 with everything working.
I have yet to find an application that does not work.
All sata ports work, my video card works, my sound works, my cd burner works.
I use it as a daily driver, it works great, it is transparent. I don't think "OMG I AM USING OSx86!" Every time I get on, I just use it as a pc.


Swedish energy giant Vattenfall hopes to expand a wind farm at the publicly-owned Clashindarroch Forest in Aberdeenshire – home to at least 13 Scottish wildcats.
With estimates for the entire population as low as 35, it is thought to be the largest single population known to exist.
Campaign group Wildcat Haven said the wind farm would "clear fell" a large amount of wildcats, "fracturing the only viable population" of the critically endangered cats.
Some 200,000 people have signed a petition demanding the Scottish Government protect the forest.
With one wind farm already in operation at the site, which was strongly opposed by the local community, the second would see a quarter of the forest felled.
Wildcat Haven said that 30 per cent of the estimated population in the country could be lost, driving forward the extinction of the species.
The rest of Scotland's wildcats survive in small, isolated pockets spread across the Highlands.
Forestry Commission Service (FCS) emails released under the Freedom of Information Act have highlighted the threat to the cats.
An email from district manager John Thomson to senior FCS staff said: "We have two very significantly scaled wind farm proposals in the pipeline for Clashindarroch. They are probably below the radar for most at the moment.
"Significant clear felling [of trees] is likely to be relevant to both.
Wildlife filmmaker and expert wildcat conservationist Steve Piper, who started the petition, slammed the development as "shameful".


Nestled mile-high in the foothills of the San Bernardino Mountains, within the historic farming community of Oak Glen, lies The Wildlands Conservancy's Oak Glen Preserve. The 2,189-acre preserve is home to the Conservancy's Southern California Montane Botanic Garden and Children's Outdoors Discovery Center. SBVAA has partnered with the conservancy to organize public outreaches and hold club star parties at the Oak Glen preserve. The altitude is approximately 5,000 feet so nights can be chilly.


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HomeNewsTrump's Bay Of Pigs
Trump's Bay Of Pigs
January 31, 2017 Larry M. Elkin
The rollout of President Donald Trump's executive order on immigration (though not necessarily the order's overall thrust) was a rookie mistake – a colossal brain freeze on which the already-mobilized "resistance" to his presidency promptly and effectively capitalized.
Even the most talented rookies make rookie mistakes, however. Everyone expects them, and they seldom are serious enough to permanently mar an athlete's record, or a president's.
John F. Kennedy authorized the ill-fated Bay of Pigs invasion, in which U.S.-backed insurgents tried to topple Fidel Castro. Woefully unprepared, practically none made it off that Cuban beach except in the custody of Castro's forces. Kennedy may have had misgivings about the CIA-sponsored coup plot he inherited from the Eisenhower administration, but he had campaigned as a war hero and military hard-liner who was going to close the missile gap and curb Communist expansionism. So he went along.
The Bay of Pigs helped provoke the Cuban missile crisis the following year. But Kennedy learned from his mistake. When he confronted the Soviets over their missile installations in October 1962, he rejected the immediate use of force and imposed a blockade (which he euphemistically called a "quarantine") around the island to prevent Moscow from completing its project. He also quietly signaled to the Soviets that if they removed their missiles from Cuba, the U.S. would remove its own missiles from Turkey sooner rather than later.
Three months after his own inauguration, Jimmy Carter informed us that the "energy crisis" was the "greatest challenge our country will face during our lifetimes" and called it "the moral equivalent of war." He told citizens to pull on our sweaters, turn down our thermostats and lower our expectations. But Carter had no plan to win the war he had just declared. Price controls and a "windfall profit tax" on oil companies practically guaranteed less domestic production and greater dependence on OPEC, which continued to boost global prices and restrict output.
Unlike JFK, Carter never learned from his mistake; he doubled down on it. When prices surged and gasoline lines spread across the country in 1979, Carter blamed the citizenry – his own soldiers in the "war" he had declared – for exhibiting a national malaise. Looking back, you would almost think Carter was running against a second term, rather than for one. President Droopy Drawers was trounced in 1980 by the ever-sunny former actor, pitchman and California governor, Ronald Reagan.
On the surface, Reagan seemed to skate through his first year in office. But when what we would later call the AIDS crisis surfaced during the summer of 1981 (we did not have that name for another year), Reagan made his rookie mistake by dismissing or downplaying the ramifications of what some were calling the "gay plague." America lagged for several years in researching and developing therapies for the devastating new disease, and the administration did not react forcefully until after AIDS began spreading into the straight and non-drug-using population, largely through contaminated blood transfusions. The ensuing alienation of the gay community from the Republican Party persists to this day – so deeply, in fact, that the prolonged opposition by leading Democrats to same-sex marriage is all but forgotten, or at least forgiven.
George H.W. Bush made his error before he even took office, on the night he was nominated. "Read my lips: no new taxes," he declared at the 1988 GOP convention. Even Reagan had accepted a rollback of his signature 1981 tax cut to boost revenue before the huge tax overhaul that was enacted a few years later. When budget pressures ultimately forced Bush to accept a tax increase, neither his own party nor the opposition ever let him forget it.
Bill Clinton's rookie mistake was the controversial development and unsuccessful advocacy of health care reform under his wife's direction. "Hillarycare" contributed to Democrats' loss of their House majority in 1994, the first time in decades Republicans had secured a majority in that chamber.
Between the controversy over his whisker-thin electoral victory and the shock of 9/11, George W. Bush scarcely had time to make a rookie mistake in his first year. So he made it in his second, by presenting the forthcoming invasion of Iraq – easily justifiable on other grounds – as a response to Saddam Hussein's development of weapons of mass destruction. Bush's credibility was badly damaged when it became clear such weapons did not exist, although he still won re-election in 2004.
Barack Obama's term is too recently ended to have consensus over whether he made a rookie mistake, and exactly what it was if he did. I would argue that his "elections have consequences" arrogance, coupled with the intensely partisan way in which his party passed stimulus measures and the Affordable Care Act, qualify for the title. The president famously took a "shellacking" in the 2010 congressional midterms, while Democrats steadily lost ground at both the state and federal levels throughout his tenure.
A common thread in all these famous blunders is a tendency to speak, or occasionally to act, without appearing to have a Plan B for dealing with failure or even with predictable opposition. This is exactly what happened to Trump when he announced a temporary ban on entry to the U.S. for travelers from seven largely Islamic countries that either sponsor terrorism (Iran) or in which terrorist organizations control territory or have a base of operations.
The executive order, which was both signed and implemented on Friday, triggered confusion and protests at airports nationwide. White House press secretary Sean Spicer defended the abrupt implementation of the order, claiming that a prior announcement would have created a window during which people would have "flooded into the country in a short amount of time to take advantage before the ban went into effect." However, by implementing the order immediately, the administration caused uneven enforcement, including long detentions and at least some deportations. Legislators from both sides of the aisle expressed concern at the way in which the order was implemented.
Despite the arguments of its critics, the order was far from a "ban on Muslims," leaving out nations that contain the vast majority of the globe's Islamic population. But the White House knew, or should have known, that its political opposition was eagerly awaiting the next set of "victims" of Trump policies to publicize, and a label in which to wrap what would have been the weekend's inevitable protests. The administration obligingly delivered.
There was never any basis or sense in including American permanent residents, or "green card" holders, in the order, which would have excluded individuals based on just the random accident of whether they happened to be outside the country. The Department of Homeland Security has clarified that this apparently was never intended. But the White House sent mixed messages, leaving border agents to sort things out after the order went into effect. This led to prominent American residents, such as British Olympic athlete Mo Farah, to protest that they feared exclusion from their home and separation from their families – although it turns out this was never truly in the cards.
It would have been a simple matter to allow all visa holders who were already in transit to clear U.S. customs and immigration formalities. This would have prevented the airport detentions and the Trump "defeats" that the media pronounced when several federal judges temporarily enjoined officials from returning those who had already arrived to their countries of origin. Most were eventually admitted anyway, but only after hours of detention and after attracting throngs of demonstrators and lawyers to airports to protest. Allowing visa holders through also would have avoided the spectacle of Iraqis and others who had helped American soldiers being barred from this country while virtually at its doorstep.
Now that the dust has settled, those who are covered by the order are, in nearly all cases, simply waiting in places where they have already been waiting for years for a chance to come here. A few more months of delay will make little practical or political difference, other than to those directly affected and their families. This is not a trivial matter, but it is not a political crisis for Team Trump, either. A little forethought could have avoided a lot of mess.
But Trump and his administration are rookies. They seem to think they need to accomplish the entire agenda for his first 100 days in office in just the first 10 or 20. Or maybe it is a deliberate strategy to take so many controversial steps so quickly that the resistance does not know which ones to resist soonest or hardest. With Trump it can be hard to tell. He makes a lot of apparent mistakes, but so far they have not hurt him much. And when it comes to blunders by presidential rookies, history has shown that more often than not, any damage is transient.
About Larry M. Elkin	564 Articles
Affiliation: Palisades Hudson Financial Group
Larry M. Elkin, CPA, CFP®, has provided personal financial and tax counseling to a sophisticated client base since 1986. After six years with Arthur Andersen, where he was a senior manager for personal financial planning and family wealth planning, he founded his own firm in Hastings on Hudson, New York in 1992. That firm grew steadily and became the Palisades Hudson organization, which moved to Scarsdale, New York in 2002. The firm expanded to Fort Lauderdale, Florida, in 2005, and to Atlanta, Georgia, in 2008.
Larry received his B.A. in journalism from the University of Montana in 1978, and his M.B.A. in accounting from New York University in 1986. Larry was a reporter and editor for The Associated Press from 1978 to 1986. He covered government, business and legal affairs for the wire service, with assignments in Helena, Montana; Albany, New York; Washington, D.C.; and New York City's federal courts in Brooklyn and Manhattan.
Larry established the organization's investment advisory business, which now manages more than $800 million, in 1997. As president of Palisades Hudson, Larry maintains individual professional relationships with many of the firm's clients, who reside in more than 25 states from Maine to California as well as in several foreign countries. He is the author of Financial Self-Defense for Unmarried Couples (Currency Doubleday, 1995), which was the first comprehensive financial planning guide for unmarried couples. He also is the editor and publisher of Sentinel, a quarterly newsletter on personal financial planning.
Larry has written many Sentinel articles, including several that anticipated future events. In "The Economic Case Against Tobacco Stocks" (February 1995), he forecast that litigation losses would eventually undermine cigarette manufacturers' financial position. He concluded in "Is This the Beginning Of The End?" (May 1998) that there was a better-than-even chance that estate taxes would be repealed by 2010, three years before Congress enacted legislation to repeal the tax in 2010. In "IRS Takes A Shot At Split-Dollar Life" (June 1996), Larry predicted that the IRS would be able to treat split dollar arrangements as below-market loans, which came to pass with new rules issued by the Service in 2001 and 2002.
More recently, Larry has addressed the causes and consequences of the "Panic of 2008″ in his Sentinel articles. In "Have We Learned Our Lending Lesson At Last" (October 2007) and "Mortgage Lending Lessons Remain Unlearned" (October 2008), Larry questioned whether or not America has learned any lessons from the savings and loan crisis of the 1980s. In addition, he offered some practical changes that should have been made to amend the situation. In "Take Advantage Of The Panic Of 2008" (January 2009), Larry offered ways to capitalize on the wealth of opportunity that the panic presented.
Larry served as president of the Estate Planning Council of New York City, Inc., in 2005-2006. In 2009 the Council presented Larry with its first-ever Lifetime Achievement Award, citing his service to the organization and "his tireless efforts in promoting our industry by word and by personal example as a consummate estate planning professional." He is regularly interviewed by national and regional publications, and has made nearly 100 radio and television appearances.
Visit: Palisades Hudson
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text:
The 2016 NTEA Work Truck Show
8-Lug Magazine events
Indianapolis Welcomes the NTEA and Its Very Cool Trucks
Photographers: Brett T. Evans, Courtesy of the NTEA
One year ago, the National Truck Equipment Association (NTEA) Work Truck Show set records for total attendance. That record lasted…exactly one year. With 11,905 industry professionals in attendance, more people took advantage of the Indiana Convention Center's hospitality this year than ever before.
That friendliness was in full swing throughout Indianapolis as well, with a variety of events around the city tailor-made for NTEA members and Work Truck Show attendees. Those perks included the WTS Blues Bash at the famous Slippery Noodle Inn, featuring the Jeremiah Johnson Band. Great blues music and fried food made the event difficult to pass up.
Guests at the Work Truck Show included Reuben Sarkar, deputy assistant secretary for transportation at the U.S. Department of Energy, who also gave the keynote address at the NTEA Green Truck Summit. Making an appearance as the headliner at the President's Breakfast was none other than Jay Leno, the late-night TV juggernaut whose love of vehicles is well documented. His remarks were hilarious and insightful, and he knew he was talking to fellow enthusiasts when he joked about his personal fleet and how much work it took to keep all those cars and trucks in good shape.
As with last year, attendees to the show hailed from all 50 states, 8 Canadian provinces, and more than 12 countries. The show floor was open for four days, allowing each visitor to appreciate the wares of hundreds of vendors, including OEMs like Ford, Chevrolet, Nissan, Ram, and GMC, as well as medium- and heavy-duty manufacturers like Mack, Kenworth, and International. Also on hand were vehicle upfitters and accessory companies, providing truck caps, snowplows, telematics systems, dump bodies, and literally thousands of other parts and products.
Making an appearance at this year's show was the Work Truck Show Ride-and-Drive, which gave visitors the chance to drive or ride in a number of vehicles, including the Hino 195h hybrid cabover truck, Lightning Hybrids' Ford E-450 hydraulic hybrid, and a variety of clean-diesel, gasoline, natural gas, and propane trucks. We got behind the wheel of several, and the future of green trucks is very good.
Coming home with a memory card full of photos, we're gonna try and tell you everything you need to know about the 2016 Work Truck Show—and you can bet we're counting down the time until the 2017 show March 14-17, 2017.
Photo 2/37 | 002 2016 NTEA Work Truck Show
If you want a 1-ton Chevrolet Suburban, better enlist at your local fire academy. This Suburban 3500 is proof that Chevrolet commercial vehicles don't have to all be trucks, box vans, and cab chassis. With a well-organized interior and boyhood-dreams paintjob, it had us all jonesing for an eight-lug Suburban.
Isuzu took center stage at the Work Truck Show, using the event as an opportunity to unveil the '18 FTR Class 6 truck. The FTR's 5.2L turbodiesel I-4 is a first in the segment, bringing new levels of fuel economy and clean emissions to the table. The low-cab-forward design is another Isuzu staple, and the company claims it'll be more maneuverable than its competitors.
The Ford F-Series Super Duty chassis cab was revealed at the 2016 Work Truck Show, giving the heavy-duty pickup lineup a few more body configurations from which to choose. This SuperCab chassis would be a good match for family businesses, although most fleets will choose the regular cab.
This Altec crane-bodied '17 Super Duty is one of the first applications of the truck's new chassis cab. Another variation on the theme was the F-450 tow truck. During the course of the week, we saw the same group of 10-year-old kids stop to ogle the truck at least two or three times.
Mercedes-Benz's surprising proliferation of work trucks was on display, with this wild tilt-bed Sprinter being its centerpiece. Dual rear wheels, beadlocks, exhaust stacks, lizard-green headlights, and a faux-mud wrap job made this Benz even more ostentatious than those owned by the Kardashians.
The International HX-Series was another new-vehicle debut at the Work Truck Show. Available with either a set-forward or set-back front axle and two hood heights, the HX is designed to be International's rugged-service truck, destined for foresting, concrete-mixing, and heavy hauling. Navistar and Cummins engines are on offer.
No 2016 show circuit would be complete without an appearance by the Nissan Titan XD. This Pro-4X model is one of the hardest-working fullsize trucks on the market today, thanks in part to its 5.0L Cummins V-8.
The Work Truck Show's primary focus is truck equipment. That much is apparent when inspecting this Masterack-modified Ford Transit Connect. A lockable file cabinet is mounted just inside the sliding door, while easily configurable drawers reside in the cargo bay. For plumbers, pest control technicians, and odd-jobs contractors, a setup like this is ideal.
Showing the flexibility of the work truck market, Isuzu treated attendees to two forms of frosty refreshment. Both the Red Bull and Schwann's Isuzu NPR trucks were perpetually stocked with enough fuel to keep every guest riding a caffeine and sugar high.
One of the coolest vehicles at the show wasn't the most obvious. This Western Star 4700SB was equipped with a massive Holland mobile welder, and the rail attachments mean this thing is ready to repair broken-down freight trains and train cars. Talk about a big job!
Photo 16/37 | 016 2016 NTEA Work Truck Show
Cummins had a very impressive display that showcased the hierarchy of its bread-and-butter engines. At the top of the heap was an example of the original 5.9L I-6 that appeared in the first Cummins-powered Dodge Ram, with the successive generations appearing underneath.
Freightliner's line of multipurpose trucks was represented in part by the popular M2 and severe-duty 108SD. There was also a Freightliner-badged Sprinter in the display, reminding us how closely linked the company is with Mercedes-Benz.
Chevrolet is reentering the medium-duty segment with the low-cab-forward 3500, 4500, and 5500. Featuring either a gas 6.0L V-8, a diesel 3.0L I-4, or a diesel 5.2L I-4, the Chevy will have a maximum payload of nearly 13,000 pounds. If it looks familiar, that's because it's based heavily on the Isuzu NPR, although General Motors did have a significant role in developing its engines.
Kenworth's T880 concrete mixer was a fun truck to play around in. The whole Work Truck Show was like a little kid's daydreams: big trucks, heavy equipment, and power tools.
This Western Star featured a Brandon Manufacturing body and one of the few truly custom paintjobs at the show. That's because it's a privately owned vehicle, operated by Weber Landscaping in Muskego, Wisconsin.
Since environmentally friendly trucks were a focus of this year's show, the Mitsubishi Fuso Canter E-Cell showcased its all-electric, zero-emissions platform. A prototype that was tested by the city of Lisbon, Portugal, was also on hand to drive during the event's Green Truck Ride-and-Drive.
Attendees who had commercial driver's licenses were able to drive the variety of Kenworth, International, and Freightliner trucks at the Ride-and-Drive, while anyone with a conventional license could sample the smaller trucks.
Compact vans got their due at the show as well, with the Ram ProMaster City seeing duty as a scuba machine and the Nissan NV200 showing up dressed like a refrigerator.
Alliance Autogas put its money where its mouth was and proved how quick the company's propane-gasoline bi-fuel conversion is to install. Two Alliance Autogas technicians were able to convert this custom Ford F-150 in a little more than 90 minutes—live on the show floor.
You couldn't walk 20 feet without bumping into a Ram. These three were our favorites: the ultra-HD Ram 5500, Ram 3500 single-cab dualie, and, of course, the AEV Prospector. That last one was unusual because it wasn't fit with any kind of bed, but that just made it cooler.
Ranger Design's booth was one of the largest, showing all kinds of storage and interior solutions for Ford, Ram, Chevrolet, and Mercedes-Benz vans.
This forms the basis of Motiv Power Systems' all-electric Ford F-59 chassis. Returning for another year at the Work Truck Show, Motiv had lots of great news, including more and more customers adopting its 100-mile range, along with some extra cash flow. Next year, the company hopes to provide a truck for the Ride-and-Drive.
Westin Truck Bodies showed off its custom Chevrolet Silverado, including a whole bed full of Brute toolboxes. The truck's off-road tires and other modifications were pretty cool as well.
Since Mack is one of the most famous names in trucking, seeing the company's bulldog on the show floor felt like meeting a celebrity.
Jay Leno had the entire audience in stitches following his keynote appearance at the NTEA President's Breakfast. He's even funnier in person, trust us. (Photo courtesy of the NTEA.)
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package org.qi4j.api.mixin.privateMixin;

import org.qi4j.api.entity.EntityComposite;
import org.qi4j.api.mixin.Mixins;

// START SNIPPET: private
@Mixins( CargoMixin.class )
public interface Cargo extends EntityComposite
{
    String origin();

    String destination();

    void changeDestination( String newDestination );

}

// END SNIPPET: private


Do you have time on your hands? Would you love to get out and meet poeple? Are you proud of Chesterfield, its present and its history?
Then why not volunteer with us Chesterfield Visitor Information Centre and Chesterfield Museum are looking for friendly outgoing people to help visitors get the most from Chesterfield. Take a look at the task descriptions below.
We are also on the look out for people to become Chesterfield Museum Ambassadors. Too many people don't think Chesterfield has a Museum and those who do know about it, don't know what we do, so we need your help to tell local people and organisations what we can offer - it's more than you think!
Take a look at the task description below and see what you think.
Full training will be given, we are able to pay expenses but only for people travelling within Chesterfield Borough.


text:
from netforce.model import Model, fields

class ContactCateg(Model):
    _name = "contact.categ"
    _string = "Contact Category"
    _key = ["code"]
    _name_field = "name"
    _fields = {
        "name": fields.Char("Category Name", required=True, search=True),
        "code": fields.Char("Category Code", search=True),
        "parent_id": fields.Many2One("contact.categ", "Parent", search=True),
        "description": fields.Text("Description"),
        "comments": fields.One2Many("message", "related_id", "Comments"),
        "full_name": fields.Char("Full Name", function="get_full_name"),
    }
    _order = "code"

    def get_full_name(self, ids, context={}):
        vals = {}
        for obj in self.browse(ids):
            n = obj.name
            p = obj.parent_id
            while p:
                n = p.name + " / " + n
                p = p.parent_id
            vals[obj.id] = n
        return vals

ContactCateg.register()


text:
Features· Pearls
Pearls are some of the most coveted stones in the world…and for very good reasons. However, not all pearls are created equal.
How are Pearls Formed?
There are several factors that weigh into how pearls are formed. One of the biggest being that—depending on the type of pearl—it either formed naturally or was cultivated by man.
Over the next few minutes, you'll learn about several of those factors and how they affect the overall quality and authenticity of a pearl.
Specifically, I'll be answering four main questions that a lot of pearl lovers instinctively consider once they begin their research into these precious gems:
How does a pearl form?
How long does it take for a pearl to form?
What are the differences between natural, cultured, and imitation pearls?
The goal of this article is to communicate an educated perspective of what pearls are and the modern creation of natural, cultured, and artificial pearls.
Question 1: What is a Pearl?
In simplest terms, a pearl is gemstone that is formed under the shell of a saltwater or freshwater species from the mollusk family.
While nearly all mollusks are able to produce pearls, the pearls used in the global jewelry industry come from mollusks whose shell is lined with a substance called nacre. The most common mollusks that produce pearls are oysters, clams, and mussels.
The beauty of pearls is that they form while the animal is alive. Though, as you'll soon learn, the birth of a pearl is not an overnight process.
Question 2: How does a Pearl form?
The formation of a pearl is a phenomenon that many seek to understand in greater detail.
A pearl is the byproduct of a mollusk's effort to protect itself from a foreign object (an irritant) that has entered its shell.
The foreign object is "attacked" by the mollusk through the secretion of a strong, smooth, opaline substance called nacre. The mollusk continues to secrete nacre for as long as the object is present in its body. Hence, over time, these layers of nacre deposit form into a pearl and gains in both size and luster.
Nacre is referred to as the mother of pearl and naturally coats the inner lining of most mollusks' mantle, including clams, oysters, and mussels.
The Irritant
The irritant that enters the body of the mollusk serves as the nucleus of the pearl that is formed.
That irritant can either occur naturally or be placed by man. The difference between natural and man-made irritants is significant to the type of pearl that is produced.
Natural irritants include things such as sand, bacteria, and pieces of mantle (the outer wall of the inner part of the mollusk's shell). When a natural irritant is at the core of a pearl, the pearl produced is natural.
An unnatural or man-made irritant is one that is placed inside a clam, oyster, or mussel. An unnatural irritant is generally a sample of mantle tissue taken from another mollusk of the same species. When an unnatural irritant is at the core of a pearl, the pearl produced is cultured.
Question 3: How long does it take for a Pearl to form?
The time it takes for a pearl to form depends largely on the type of pearl that is being made.
The creation process for natural and cultured pearls can take anywhere from six months to 20 years!
Fun Fact: The first pearl was discovered some 530 million years ago!
The specie of mollusk and the environment in which it lives are two factors that contribute to how long it takes for a pearl to form:
Saltwater Pearls versus Freshwater Pearls
Saltwater pearls are produced by mollusks living in a saltwater environment, specifically the Atlantic, Indian, and Pacific oceans. The period of maturity for saltwater pearls can be as short as three years to as long as 20 years.
The average amount of time it takes for a saltwater pearl to form is five years. Also, the bulk of saltwater pearls are produced by saltwater oysters.
Freshwater pearls are mainly cultured pearls that are produced by mollusks living in man-made reservoirs, lakes, mollusk farms, and other water habitations. The bulk of these pearls are produced in China. The period of maturity for freshwater pearls can be as short as six months to as long as six years.
The average amount of time it takes for a freshwater pearl to form is 24 months. Also, the maority of freshwater pearls are produced by freshwater mussels.
Question 4: What is the differences between natural, cultured, and imitation pearls?
As you learned earlier, pearl creation is driven by several distinct factors. Based on those factors, you'll be able to tell if you're dealing with a natural, cultured, or imitation pearl.
Natural Pearls
The most beloved of all pearl types is the natural pearl—however, it is also the rarest and, when one is obtainable, the most expensive.
The natural pearl is one whose formation was completely caused and controlled by the naturally-occurring processes of nature. In other words, there was no human intervention at all.
Today, getting ahold of a natural pearl is not an easy (or affordable) task, as these pearls are reserved for fine jewelry producers, connoisseurs, and collectors.
Cultured pearls undertake the same growth journey as natural pearls. But there are two distinct differences between a natural pearl and one that is cultured:
Cultured pearls are primarily produced by mollusks who live in controlled environments (e.g., mollusk farms; man-made reservoirs)
Cultured pearls are the result of irritants that were intentionally introduced to the mollusk
Human intervention during the growth of a cultured pearl means that the entire process can be closely monitored and pearls can be produced according to strict standards and other industry expectations.
The largest and most beautiful cultured pearls are those that have been cultured for at least two to three years.
Today, cultured pearls account for more than 95% of pearls sold in the retail market.
Imitation Pearls
As the name suggests, imitation pearls are fake pearls. These pearls are also called artificial pearls, simulated pearls, man-made pearls, wax pearls, and alternative pearls.
Imitation pearls are created entirely by man and are most commonly produced using plastic, ceramic, glass, crystal, mollusk shell, or some combination of these as the nucleus, or center, of the pearl.
The faux luster and imitated value of the pearl is produced by coating the product with a chemical solution. Nevertheless, improved technologies and production standards have paved the way for imitation pearls to boast similar luster and value as their cultured and natural cousins.
Though fake pearls are far from the real thing, their reputation is surprisingly strong—mainly because real pearls are not affordable for the everyday pearl lover. As a result, simulated pearls help produce a sense of affordable luxury and charm for the wearer. Today, the epicenter of the imitation pearl industry is Majorca, Spain.
Again, no two pearls are created equal.
Natural and cultured pearls vary drastically in everything from size and color, to luster, shape, and type. However, every aspect of a pearl is unique to it, making its value unique as well.
How to Clean Pearl Jewelry
How to Wear the Right Pearl Necklace with the Right Neckline
Which Pearls are the Best?
10 Fun Facts About Pearls
Choosing a Pearl
« Which Pearls are the Best?
How to Wear the Right Pearl Necklace with the Right Neckline »


It's no secret the Dallas Cowboys' fan base is tired of the same beat skipping over and over again like a broken record. For three consecutive seasons, the fate of the Cowboys' season has come down to the regular season finale, a win or go home game, a game that decided the outcome of the NFC East division.
division. And they've come up short against every division rival starting with the New York Giants in 2011, the Washington Redskins in 2012, and the Philadelphia Eagles this past season at AT&T Stadium.
Just when you thought a Week 16 clutch Tony Romo performance that kept the Cowboys' season alive, with a do or die game-winning touchdown pass to DeMarco Murray on fourth-and-goal from the Washington 10-yard line could turn the tides over as a momentum-builder for the division crown, the "Gypsy Curses" arrived at their doorstep once again. Although this time, it wasn't going to be a late-game Romo-blunder like the previous season at FedEx Field, a game Romo threw the decisive interception with the Cowboys trailing by only three, 21-18, with a chance to tie or punch it in the endzone for the go ahead score.
A back-injury ended Romo's season in one of his memorable 4th quarter performances, banged up and carrying the team on his back. Without Romo under center for the divisional title game, it was left up to backup Kyle Orton with the season on the line. Orton threw for 358-yards and 2-touchdown passes, but of his two interceptions, the second was the decisive game-ending turnover that ended the Cowboys' season and crowned the Philadelphia Eagles as NFC East champs.
Same ending, same kick in the stomach, same heartache, and the days go on and on. Disappointment always waits for Dallas fans at the end of the road. No more pot of gold, no nothing but an offseason of remembering how they blew it again. From poor coaching to mistakes in critical moments, the saga in the life of being a fan of "America's Team" has turned into a cold-sweating nightmare that's left an extremely-large and loyal fan base bewildered, who once witnessed the ultimate-success to now being stuck in a rut, with only 2 playoff victories since January 28, 1996, the last time the Dallas Cowboys captured the Lombardi Trophy.
And when the results always end in negative-fashion, you need to make changes, financially, in the front office, coaching and personnel-wise to give your organization a better plan going forward.
So what have the Cowboys done post another regular-season-ending heartbreak?
Jason Garrett was given some juice to make changes to his coaching staff. And for once, changes weren't made by the mighty hands of Jerry and son Stephen. The defense was historically putrid in 2013, and Monte Kiffin was demoted after his first season as defensive coordinator and was replaced by the promoted from defensive line assistant to new defensive coordinator Rod Marinelli. I like this change in having a more upbeat personality that's been a defensive line coach for the majority of his 40-year coaching career. His defenses performed at a high-level in Chicago between 2010 and 2012, and the team is currently in need of rebuilding a defensive front that will be without DeMarcus Ware and Jason Hatcher.
Clearly, the club knows they must tackle defensive line in the draft, and the upcoming draft presents a good deal of lineman to choose from. In my opinion, Pittsburgh's Aaron Donald will be the best selection and proper fit for the 3-technique. I'm not banking on Donald to be around at 16 when the Cowboys are on the board, so they will likely have to trade up if they really want him. This is where Will McClay comes into play that's in charge of putting together the draft board. McClay is entering his 12th season with the Cowboys' front office. He's mostly been the director of football research and was promoted to assistant director of player personnel in June. McClay understands what the team needs and how to build.
If you want to build a dominant front in a base 4-3 defense, depth will be needed along the defensive line to build a 7-to-8 man rotation. The team is looking to get younger and faster and find value in the upcoming draft.
A couple of months ago, McClay revealed the plan going forward during a radio interview on 105.3 The Fan.
The back and forth switching of offensive play-calling between Jason Garrett and Bill Callahan has now been turned over to new offensive coordinator Scott Linehan. Although the offensive side of the ball isn't mostly where the concern is, the Cowboys believe that Linehan will bring more creativity and get everyone on the same page to eliminate situational football dysfunctions that has haunted the team. In Detroit, Linehan's offense was ranked 3rd in passing and 6th overall last season. Dallas' offense took a step back in 2013 finishing 16th overall, unlike the previous four seasons of being ranked in the top 10.
Linehan is more of a pass-first guy, but he hasn't really had a running back that can carry the load like DeMarco Murray since his days in St. Louis. With Steven Jackson as his ball-carrier, he had a 1,500-yard back. The club has been emphasizing the need to establish the running game and got the most out of Murray in his 3rd year with the team for 14 games, unlike his rookie campaign where he started only 7 and 10 in his second due to injuries. In 2013, Murray averaged 5.2-yards per carry, rushing for 1,121-yards, 9-rushing touchdowns, 53-receptions, 350-yards receiving and 1-receiving score to give him a total of 1,471-yards from scrimmage and 10-touchdowns in his most productive season.
Garrett may have ties with Linehan and be excited to have him on board, but my concern with this hire is the fact that Bill Callahan isn't the happiest camper about Linehan joining the staff. Callahan has been a good influence in improving the offensive line and getting a decent running game in place to build upon. But when you have a pass-happy type of coordinator now calling the shots, you have to wonder if this is going to be a 50/50 thing in having a balanced attack, especially when you have a defense that really doesn't show enough proof or reason at the moment on why it will be better in 2014. With a bad defense that gives up big-plays galore, you're likely to be trailing, in see-saw battles, and will be in come-from-behind mode. That calls for the offense to be more aligned on the percentage of (60-pass/40-run). That's not good, considering Tony Romo coming off two back surgeries. I'm not calling for the offense to be gun-shy on the pass, but the more you pass, the more chance of your quarterback being brought to the ground. How much longer can Romo (34) play Houdini, evading pass-rushers coming his way? That candle won't stay lit forever.
The front office has made wise decisions financially, creating flexibility for the near and futuristic plans.
Fixing the salary cap was a must, and to create space, the team first restructured the deals of Tony Romo, Sean Lee and Orlando Scandrick. The next step was to make a decision on whether or not to keep one of the franchises best ever defensive players DeMarcus Ware. Ware was set for a base salary of $12.25 million, with a cap hit of $16.003 million. Jerry Jones made it clear, either Ware takes a pay cut or the team would release him to free up $7.4 Million. Ware didn't take a cut and was released only to sign a 3-year, $30 million deal to join Peyton Manning and the Denver Broncos. And unlike years past, Jerry Jones didn't jump the gun and dish out the big bucks on an aging veteran like Jason Hatcher, who had a breakout season in a contract year. Releasing the prone to injury Miles Austin as a post June 1st cut saved them $5.5 Million that will kick in after June 1, a move the team would likely use on signing their 2014 draft picks.
Cutting salary has given the organization some flexibility to stick to their plan of going younger and not signing players over 30 and beyond that's snake-bitten them into cap-hell. Signing Terrell MClain and Jeremy Mincey was for depth purposes that came cheaply in looking to build a d-line rotation under Marinelli's defense. The team hasn't had a 3rd quarterback on the roster since 2011, and signing Brandon Weeden to a 2-year deal at the league minimum was one of the more healthy financial choices the team made in getting a quarterback with some starting experience at the cheapest price. Best move of all, the team was linked to reuniting DT Henry Melton with Marinelli this offseason and the Cowboys got him on friendly 1-year deal, with an option of 3-years if Melton can prove to the team that he's fully recovered from his ACL injury and perform at the level that earned him a trip to the Pro Bowl in 2012. Melton (27) is potentially the first piece of a building-block that will lead the Cowboys' defensive line to become a dominant force, if they strike gold in the draft and build around him.
Let's not forget about the days down in the Florida Keys, a time Jason Garrett and Troy Aikman spent with former head coach and two-time Super Bowl winner Jimmy Johnson. Garrett harassed Jimmy to the point of exhaustion on how to build a winner. Go young and fast, and apparently it's kicking in the mindset of the front office. The Cowboys have 11 draft picks to use this May, thanks to being awarded three compensatory picks for losing Victor Butler, Kenyon Coleman, Mike Jenkins and John Phillips in free agency, while only picking up Justin Durant in 2013. You can't trade your compensatory picks, but with extra picks, you have the luxury of being able to trade up or back in draft, more options, the better of finding your needs for depth, etc.
I like all of this in the avenue of understanding that football is a young man's game. That's what we have here with the Dallas Cowboys' strategy in the near future. But even with a structured-plan in place, I still question Jason Garrett as a leader of men. The head coach has to be the guy that holds the club (my way or the highway) ground rules. Didn't Jimmy Johnson create an atmosphere of (YOU CAN'T LOSE HERE) during the glory days of the 90's? That's what needs to change in Dallas. Jason Garrett needs to be the guy with the (Iron Fist) the players need to respect and fear.
Example of why Garrett lacks power from his throne: Romo switching out of the run and electing to pass that resulted in the first of two game-costing interceptions against Green Bay. Shouldn't Garrett have stepped in at the moment as head coach and demand his quarterback not to switch anything? This lends me to believe that the players don't truly fear their head coach and feel they can cut corners around him.
And recently Jerry Jones told the world that Garrett doesn't necessarily need to lead the Cowboys to the playoffs to keep his job. Is that the message you want to send to your head coach and team for motivational-purposes? You see, everything always comes back to the man (Jerry). Even when things make sense, there always has to be something that spills out of his mouth that makes you think twice.
In the meantime, Dallas fans can only hope the changes at hand will be the lead-way and beginning of something good. Keep your fingers crossed, eat your vitamins and say your prayers.


text:
Q: convert number with decimals without I make a query to mysql and I get this number:
26,613,080
and I need to convert that number to:
266,130 or 266.130 (it does not matter if it is , or . )
I was doing some tests with number format or removing the last 2 numbers but I can't get it to stay as I need.
Thanks

A: If you have the intl extension installed, you can use the NumberFormatter class for this.
$input = "26,613,080";

$numberFormatter = new NumberFormatter("en_EN", NumberFormatter::DECIMAL);
$numberValue = $numberFormatter->parse($input);

var_dump($numberValue);
// float(26613080)

// I'm using TYPE_INT32 because that removes the decimal digits without rounding.
$output = $numberFormatter->format($numberValue / 100, NumberFormatter::TYPE_INT32);

var_dump($output);
// string(7) "266,130"

redpajama_set_name: RedPajamaStackExchange


"Tampered With" was released by Lisa "Left Eye" Lopes as the B-Side to her debut solo single "The Block Party". As you may know, her debut solo album "Supernova" was eventually scrapped and never released after each of the singles released flopped. This is a gem that many don't know about because it wasn't even intended to release on that album. It's also a gem for the fact it features Wanya from Boyz II Men and Shamari from Blaque.


Digital TV allows viewers to watch crystal clear pictures, even as clear as high definition pictures.
Digital TV gives viewers variety of programmes and channels. For example in Nairobi there are over 40 channels in Digital Platform so far.
Digital TV allows hustlers to own TV Stations as production and broadcast have been separated. With a simple studio somewhere in town you can have your content viewed across the country by allowing someone like Signet to broadcast for you.
Viewers have a choice to record and watch their favorite programmes…at least most set top boxes allow that.
Personally I've been able to enjoy most of the aforementioned benefits for about two months now and I must say, largely, Digital TV is great. Actually watching Digital TV feels like watching pay TV, but it is not always rosy.
In the two months that I have watched Digital TV I have noticed two major concerns, one of them being a heartbreaking digital TV blackout.Last night there was this movie I was watching on NTV, then just when these FBI guys entered a house to ransack it for a kidnapped kid the screen went off, then a few seconds later the message "No signal" was displayed.
I quickly tried to adjust the antenna but nothing happened. Checked on the signal status and fount it OK. I switched off the set top box and on again, no change. I then did the 10 minutes miraculous switch off, switched the set top box back on, performed auto-search, but still there was no Signet Channel found.
It was now obvious – Signet's transmission had issues. I called their customer care number but no, the number wasn't going directly to Signet. Someone at KBC received the call and after I explained to him my problems he asked me to hold on as he transferred the call to the relevant department. I waited until the dial tone on other end died.
I tried to continue watching the movie from NTV's analogue transmission.One thing I learnt is the difficulty in watching analogue TV after getting used to digital signal. I stopped watching. Then I remembered the StarTimes decoder and their truly free Free to Air Channels. I connected the decoder and found the movie almost ending…*insert curse word*.
Remember the night of 26th December last year when analogue signals were switched off in Nairobi? Yes, Kenya is vulnerable to such blackouts even after the transition to digital TV if the current two-only-distributors are retained. Of the two, there is only one main signal distributor. This means every once in a while Kenyans will be treated to a digital TV blackout resulting from technical hitches on the distributor's key transmission infrastructure.
Right now Signet transmits close to 100% of Digital TVs in the market. If Signet develops technical hitches that might run into days, it means the TV programmes provided to Signet to distribute will not be available to the masses. As I write this article, I have not checked whether the Signet channels that were lost in Nakuru are back or I'm still in a Digital blackout but if past experience with KBC (owners of Signet) broadcast here in Nakuru is anything to go by, I won't be surprised if the signal is lost for weeks; or months.
In the past KBC signal had gone missing, at least in Nakuru, for months. Kiss 100 FM too lost its Nakuru signal for a period close to 3 months in the first part of last year. Capital FM also stopped transmitting in Nakuru for quite sometime in mid to late last year. What all these imply is that a particular signal distributor might lose her signals either countrywide or to a particular region for days, weeks or even months; giving people in the affected areas information blackout.
The advantage with the current analogue set-up is that if one particular channel, either Radio or TV goes off air due to a technical hitch or otherwise, one still has a number of channels on air to choose from. But allowing only one or two distributors to do the distribution work, with one of them distributing close to 100% of the available signals, means we are being treated to a monopolistic digital TV market where consumers would be grossly affected whenever the monopoly is unable to deliver the services it ought to deliver.
To prevent a total blackout to information whenever a distributor is incapacitated, the government needs to license many distributors not only to make the market competitive for TV stations (which will lower the cost of broadcasting), but also ensure that viewers are never adversely affected by technical hitches on one distributor.
Other than the possibility of a total Digital TV blackout thanks to almost all the digital signals being available to only one distributor, I have also noticed sound quality issues. In my reviews of StarTimes DVB-T2, Smart-Beaver DVB-T2 and Thy Word DVB-S2/T2 set top boxes, I have always mentioned sound as one main criteria for gauging the suitability of a set top box. But earlier this week I made an important discovery.
All DVB-T2 set top boxes have the ability to auto-search and save all the available terrestrial digital TV/Radio signals. This means a set top box like Smart-Beaver's searches and find signals as broadcast by GoTV, StarTimes, PANG (still StarTimes) and Signet. If there is a particular TV Station that every distributor broadcasts, then you'd expect to see the station listed about four times in the Channels' list. KBC is normally listed three times; first signal from GoTV, second from StarTimes and the third from Signet.
Though I'm used to watching programmes from Signet's transmission, on Tuesday I accidentally left the TV on at KBC but the signal was from GoTV. Then after a few minutes I realized there was something bad about the sound. When I pressed the OK button to see which channel had the dull sound I realized it was KBC but apparently it wasn't via Signet. When I changed the channel from GoTV's signal to Signet's the sound quality improved from boring and dull to interesting and clear.
I still do not know what exactly affects sound as even though KBC has clear and desirable sound on Signet, a few other TV stations like YouthTV and Fountain TV still have the dull and boring sound yet they too are being broadcast by Signet.
The sound issues means that with Digital TV someone might end up "hating" on some Stations simply because their sound is of poor quality compared to others. The poor sound, given the KBC's experience, means it is a transmission issue that signal distributors need to pay close attention to.


BiblePod allows you to transfer books and chapters from the King James Version bible to your iPod.
BiblePod takes use of the Notes feature built-in to 3rd generation iPods and iPod mini's to transfer books and chapters from the King James Version bible to your iPod.
· Tiger ready, but should still be compatible with 10.2.8 and up.
· 3rd generation or newer iPod (includes iPod minis and iPod photos).


How to Setup the Netgear WNA3100 Wireless Adapter?
It took me quiet a number of hours getting my WNA3100 Wireless-N 300 (broadcom) network adaper working with Linux. There were lots of questions and answers provided throughout the internet. For me, none of the answered worked. Most of them has some of the steps, but none of them had all the steps that eventually worked.
After I finally got it working, I decided to record the steps in one location for future references as well as for providing to others all the steps in one page that works (in each of my tested instances).
This was performed on Ubuntu installations.
1) Wine (Just for running the Windows driver install (setup.exe) to get the drivers.
$ sudo ndiswrapper -i [driver] # (moste likely named "bcmwlhigh5.inf"
That's all there is to it. Please view the troubleshooting section.
Run the setup.exe file with Wine Windows Program Loader to get the drivers. You'll find the drivers by navigating the "~/.wine/drive_c/Program Files (x86)/NETGEAR" area. Copy the folder (ie. WNA3100) to a convenient location. Then run "sudo ndiswrapper -i [driver]" to load the driver.
1) Make sure your USB adapter is recognized by your motherboard. If it's not recogonized either your motherboard or the adapter might be defective.
This page will be updated according to feedback and validating the clarity and functionality of these steps.


text:
PSG's Nasser Al-Khelaifi delighted with Ligue 1 title but suggests 'big goal' is Champions League
PARIS — In the wake of his latest Ligue 1 title, Paris Saint-Germain chairman and CEO Nasser Al-Khelaifi has made clear the Champions League is nonetheless his side's best goal, while also strongly suggesting that coach Unai Emery could be replaced when his contract expires at the conclusion of the season.
Talking just after PSG clinched a seventh Ligue 1 title with a 7-1 thrashing of second-positioned Monaco at Parc des Princes, the Qatari denied getting Thomas Tuchel lined up as the Spaniard's replacement.
"When we have signed a contract with someone, we will make an announcement," mentioned Al-Khelaifi to Canal+. "For the moment, very little has been finished — very little has been signed.
"At this time, we have a coach. We gained 7-1 with him and he has a contract until eventually the conclusion of the season.
"We have finished a ton of favourable factors this season. We are a winner for the seventh time, the fifth for me. It is really seriously something attractive, thank you to all people. Of training course, all people are aware, our big goal is the Champions League. But currently, we are quite happy and happy with this title."
Emery was happy with PSG's win over Monaco and the title good results, which is his initial league crown as a coach, but hinted that there is no assure that he will stay in charge of the squad previous the conclusion of the season.
"Transferring ahead, the club's emblem and supporters will stay," Emery mentioned. "Everybody else is just passing by way of. For me, I am happy with my own challenge.
"Away at Saint-Etienne previous week, it was our worst initial half of the marketing campaign. Then, at 10 against 11, we responded. That is the indication of good collective power. That is why I think in this team — with or without the need of me."
PSG defender Marquinhos praised Emery for his do the job with the group this season and Brazil worldwide disclosed his delight at his fourth Ligue 1 title.
"The coach got us to do the job, gave us a fantastic philosophy and design and style of play, generating us more attacking — it has been a fantastic season," mentioned Marquinhos. "A title is always an attractive thing, it is a portion of the tale. When our careers are over, these are the factors that we will don't forget."
Club captain Thiago Silva also backed Emery.
"I am his captain, and even if I considered to the opposite, I could not say: 'I want him to go,'" he mentioned. "I am always straightforward. In particular, about the do the job that we have finished alongside one another. I have always had his self-assurance in the identical way that we, the players, have always reliable the staff."
Javier Pastore could not don't forget that he has performed a position in all five of PSG's Ligue 1 titles in the Qatari era and admitted that he is no more time maintaining monitor but instructed that this a person could be his previous a person with the French giants.
"Truthfully, I do not know — I no more time rely upon," the Argentina worldwide mentioned. "I will do that when I leave. We will see what transpires.
"Truthfully, I do not know. We nonetheless have to have to speak with the club. It is ordinary just after getting invested several years at the club. The club has substantial ambitions and is seeking for new players, big skills. I am calm and just trying to do my finest."
Monaco's vice president Vadim Vasilyev branded the 7-1 decline "a catastrophic situation" and criticised the players for their no-display on the pitch.
"PSG gained the title in breathtaking style," mentioned the Russian. "They are deserving champions. The only kinds who were being up to the undertaking, for us, were being the supporters — I thank them.
"What to say? This was a knockdown, but not a knockout."
Meanwhile, coach Leonardo Jardim called the general performance "quite weak" and "nightmarish" and the club have verified their intention to reimburse each and everyone travelling supporter just after this kind of an unacceptable display.
This entry was posted in Latest Posts, Ligue 1, Paris Saint-Germain and tagged champions league, Ligue 1 title, PSG. Bookmark the permalink.
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Journal of Neurology and Neuromedicine 2018, 3(5):39-50 (Invited Review).
Brilaroxazine (RP5063) Clinical Experience in Schizophrenia: A New Option to Address Unmet Needs.
European Journal of Drug Metabolism and Pharmacokinetics 2018, 43:573-585.
A Population Pharmacokinetic and Pharmacodynamic Analysis of RP5063 Phase 2 Study Data in Patients with Schizophrenia or Schizoaffective Disorder.
Clinical and Translational Science 2018, 11:387-396.
Initial clinical experience of RP5063 following single doses in normal healthy volunteers and multiple doses in patients with stable schizophrenia.
Clinical and Translational Science 2018, 11:378-386.
Pharmacokinetics of RP5063 Following Single Doses to Normal Healthy Volunteers and Multiple Doses Over 10 Days to Stable Schizophrenic Patients.
Schizophrenia Research 2017, 189: 126-133.
Dopamine Serotonin Stabilizer RP5063: A Randomized, Double-blind, Placebo-controlled Multicenter Trial of Safety and Efficacy in Exacerbation of Schizophrenia or Schizoaffective Disorder.
Behavioral Brain Research 2017, 332: 180-199.
RP5063, an atypical antipsychotic drug with a novel mechanism of action, improves cognition and psychosis in mouse models of schizophrenia.
RP5063 reverses and prevents subchronic phencyclidine-induced declarative memory deficits and increases cortical dopamine in C57BL/6J mice.
New Clinical Drug Evaluation Unit (NCDEU) Conference, Hollywood, Florida, USA. May 29, 2013.
RP5063 safety and efficacy in schizophrenia and schizoaffective disorder.
New Clinical Drug Evaluation Unit (NCDEU) Conference, Phoenix, Arizona, USA. May 30, 2012.
RP5063 safety, pharmacokinetics and pharmacodynamics in schizophrenia.
Journal of Genetic Syndromes & Gene Therapy 2018, 9:43.
Pulmonary arterial hypertension and pulmonary fibrosis: treatments, unmet needs and future directions.
Journal of Genetic Syndromes & Gene Therapy 2018, 9:36.
Serotonergic targets in the treatment of pulmonary arterial hypertension (PAH) and idiopathic pulmonary fibrosis (IPF).
European J Pharmacology 2018, 827:159-166.
Evaluation of the effects of RP5063, a novel, multimodal, serotonin receptor modulator, as single-agent therapy and co-administrated with sildenafil, bosentan, and treprostinil in the monocrotaline-induced pulmonary arterial hypertension rat model.
Laxminarayan Bhat, Jon Hawkinson, Marc Cantillon, Dasharatha G Reddy, Seema R Bhat, Charles E. Laurent, Annie Bouchard, Marzena Biernat, and Dany Salvail.
RP5063 is effective in sugen-hypoxia-induced pulmonary arterial hypertension in rats.
A closure look at the preclinical experience of RP5063 in pulmonary arterial hypertension (PAH).
Laxminarayan Bhat and Dany Salvail.
European J Pharmacology 2017, 810: 83-91.
RP5063, a novel, multimodal, serotonin receptor modulator, prevents Sugen 5416-induced pulmonary arterial hypertension in rats.
European J Pharmacology 2017, 810: 92-99.
RP5063, a novel, multimodal, serotonin receptor modulator, prevents monocrotaline-induced pulmonary arterial hypertension in rats.
American Thoracic Society (ATS) International Conference, Washington DC, USA. May 19-24, 2017.
RP5063 mitigates the developments and severity of sugen-hypoxia induced pulmonary arterial hypertension in rats.
RP5063 prevents moncrotaline-induced pulmonary arterial hypertension in rats.
Reviva Pharmaceuticals Selected as a Winner of the 2018 Red Herring Top 100 Global Award.
Reviva Pharmaceuticals Chosen as a 2018 Red Herring Top 100 North America Winner.
© Reviva Pharmaceuticals Inc. © 2015. All Rights Reserved.


Questions about example sentences with, and the definition and usage of "Darja"
How do you say this in English (UK)? usko sahid ka darja milna chaiye.
Him/her should get the title of matyr.
Example sentences with, and the definition and usage of "chaiye"
Example sentences with, and the definition and usage of "milna"
Example sentences with, and the definition and usage of "sahid"
Example sentences with, and the definition and usage of "dariy"
Example sentences with, and the definition and usage of "darkish"


text:
Darren Aronofsky No Longer Directing "The Wolverine"
By: | Movie News | March 18, 2011
When director Darren Aronofsky stepped on board to direct The Wolverine for 20th Century Fox, it was a bit of an odd development. Why was he directing a mainstream superhero film? Would his style create the film that the studio wanted? Would we see Uncle Hank?
Well, it looks like he's leaving. According to The Hollywood Reporter, Aronofsky has left the project, stating that "the project would keep him out of the country for too long."
His exact words:
"As I talked more about the film with my collaborators at Fox, it became clear that the production of The Wolverine would keep me out of the country for almost a year. I was not comfortable being away from my family for that length of time. I am sad that I won't be able to see the project through, as it is a terrific script and I was very much looking forward to working with my friend, Hugh Jackman, again."
Despite Aronofsky's departure, Fox is still making the film, and Hugh Jackman is still on board to play Wolverine.
As much as I love Aronofsky, I don't particularly mind this decision at all. Directing a film like "Wolverine" would likely mean a drastic change in his directing style, and that's not the Aronofsky I personally want to see.
How do you feel about Darren Aronofsky leaving the helm of The Wolverine?


Reimers Electra Steam is a manufacturer of electric steam boilers for a variety of commercial baking equipment applications, such as, proof boxes, ovens, & other food and bakery equipment. Our boilers are used by restaurants, bakeries, and other establishments that engage bakery steamers. O.E.M.& bakery equipment suppliers are needed.
Electric boilers make an ideal steam generator for bread baking. They are small and require no venting. They can be attached directly to the oven or proofer to provide a high quality heat & steam source. The saturated steam from our boilers can be controlled as to pressure which will vary the temperature and BTU transfer of the steam. We offer a variety of models from 1.5 to 500 KW to match any steam application. Reimers can customize your order with timers, steam manifolds, and other essential items necessary for a quality installation.
Pan Size: 16" x 26"