text:
Infection and vaccination in chronic fatigue syndrome: Myth or reality?
Shmuel Appel, Joab Chapman, Yehuda Shoenfeld
Chronic fatigue syndrome (CFS) is characterized by severe disabling fatigue lasting for more than 6 months associated with physical and mental disturbances such as headache, arthralgia, myalgia, memory impairment, sore throat and tender lymph nodes. The exact pathogenesis is still unknown. Several models were proposed to explain its etiology including chronic infection, endocrine dysfunction, autonomic imbalance, depression, decreased immunity states and an aberrant reaction to infection. No convincing evidence was found to support any of the suggested pathogenic mechanisms. The current concept is that CFS pathogenesis is a multi factorial condition in which an infective agent cause an aberrant immune response characterized by a shift to Th-2 dominant response. When the response fails to be switched-off, a chronic immune activation occurs and clinically expressed as the symptomatology of CFS. Vaccinations are used in order to stimulate the immune system to induce a persistent immunity against the favorable antigens. Several syndromes that contain chronic fatigue as one of their symptoms, such as "Gulf war syndrome" and macrophagic myofasciitis were related to vaccinations. Can vaccinations induce the aberrant immune response of CFS? Little is known about this issue. There are some reports on CFS occurring after vaccination, but few prospective and retrospective studies failed to find such an association. A working group of the Canadian Laboratory Center for Disease Control (LCDC) that was founded in order to examine the suspected association between CFS and vaccinations concluded that there is no evidence that relates CFS to vaccination. Further studies are requested to examine this issue since it is very conceivable that if infection can lead to CFS, vaccination may also lead to it in the same immune-mediated pathogenesis.
Th-2 immune response
Dive into the research topics of 'Infection and vaccination in chronic fatigue syndrome: Myth or reality?'. Together they form a unique fingerprint.
Chronic Fatigue Syndrome Medicine & Life Sciences 100%
Vaccination Medicine & Life Sciences 62%
Macrophagic myofasciitis Medicine & Life Sciences 16%
Persian Gulf Syndrome Medicine & Life Sciences 15%
Immunity Medicine & Life Sciences 14%
Pharyngitis Medicine & Life Sciences 10%
Myalgia Medicine & Life Sciences 9%
Appel, S., Chapman, J., & Shoenfeld, Y. (2007). Infection and vaccination in chronic fatigue syndrome: Myth or reality? Autoimmunity, 40(1), 48-53. https://doi.org/10.1080/08916930701197273
Appel, Shmuel ; Chapman, Joab ; Shoenfeld, Yehuda. / Infection and vaccination in chronic fatigue syndrome : Myth or reality?. In: Autoimmunity. 2007 ; Vol. 40, No. 1. pp. 48-53.
@article{2c2c69eb3fcc411d9441cd109d608fb5,
title = "Infection and vaccination in chronic fatigue syndrome: Myth or reality?",
abstract = "Chronic fatigue syndrome (CFS) is characterized by severe disabling fatigue lasting for more than 6 months associated with physical and mental disturbances such as headache, arthralgia, myalgia, memory impairment, sore throat and tender lymph nodes. The exact pathogenesis is still unknown. Several models were proposed to explain its etiology including chronic infection, endocrine dysfunction, autonomic imbalance, depression, decreased immunity states and an aberrant reaction to infection. No convincing evidence was found to support any of the suggested pathogenic mechanisms. The current concept is that CFS pathogenesis is a multi factorial condition in which an infective agent cause an aberrant immune response characterized by a shift to Th-2 dominant response. When the response fails to be switched-off, a chronic immune activation occurs and clinically expressed as the symptomatology of CFS. Vaccinations are used in order to stimulate the immune system to induce a persistent immunity against the favorable antigens. Several syndromes that contain chronic fatigue as one of their symptoms, such as {"}Gulf war syndrome{"} and macrophagic myofasciitis were related to vaccinations. Can vaccinations induce the aberrant immune response of CFS? Little is known about this issue. There are some reports on CFS occurring after vaccination, but few prospective and retrospective studies failed to find such an association. A working group of the Canadian Laboratory Center for Disease Control (LCDC) that was founded in order to examine the suspected association between CFS and vaccinations concluded that there is no evidence that relates CFS to vaccination. Further studies are requested to examine this issue since it is very conceivable that if infection can lead to CFS, vaccination may also lead to it in the same immune-mediated pathogenesis.",
keywords = "Chronic fatigue syndrome, Infection, Th-2 immune response, Vaccination",
author = "Shmuel Appel and Joab Chapman and Yehuda Shoenfeld",
note = "Funding Information: This work was partly supported by The Fundation Federico SA, for research in Autoimmunity Diseases.",
journal = "Autoimmunity",
Appel, S, Chapman, J & Shoenfeld, Y 2007, 'Infection and vaccination in chronic fatigue syndrome: Myth or reality?', Autoimmunity, vol. 40, no. 1, pp. 48-53. https://doi.org/10.1080/08916930701197273
Infection and vaccination in chronic fatigue syndrome : Myth or reality? / Appel, Shmuel; Chapman, Joab; Shoenfeld, Yehuda.
In: Autoimmunity, Vol. 40, No. 1, 01.02.2007, p. 48-53.
T1 - Infection and vaccination in chronic fatigue syndrome
T2 - Myth or reality?
AU - Appel, Shmuel
AU - Chapman, Joab
AU - Shoenfeld, Yehuda
N1 - Funding Information: This work was partly supported by The Fundation Federico SA, for research in Autoimmunity Diseases.
N2 - Chronic fatigue syndrome (CFS) is characterized by severe disabling fatigue lasting for more than 6 months associated with physical and mental disturbances such as headache, arthralgia, myalgia, memory impairment, sore throat and tender lymph nodes. The exact pathogenesis is still unknown. Several models were proposed to explain its etiology including chronic infection, endocrine dysfunction, autonomic imbalance, depression, decreased immunity states and an aberrant reaction to infection. No convincing evidence was found to support any of the suggested pathogenic mechanisms. The current concept is that CFS pathogenesis is a multi factorial condition in which an infective agent cause an aberrant immune response characterized by a shift to Th-2 dominant response. When the response fails to be switched-off, a chronic immune activation occurs and clinically expressed as the symptomatology of CFS. Vaccinations are used in order to stimulate the immune system to induce a persistent immunity against the favorable antigens. Several syndromes that contain chronic fatigue as one of their symptoms, such as "Gulf war syndrome" and macrophagic myofasciitis were related to vaccinations. Can vaccinations induce the aberrant immune response of CFS? Little is known about this issue. There are some reports on CFS occurring after vaccination, but few prospective and retrospective studies failed to find such an association. A working group of the Canadian Laboratory Center for Disease Control (LCDC) that was founded in order to examine the suspected association between CFS and vaccinations concluded that there is no evidence that relates CFS to vaccination. Further studies are requested to examine this issue since it is very conceivable that if infection can lead to CFS, vaccination may also lead to it in the same immune-mediated pathogenesis.
AB - Chronic fatigue syndrome (CFS) is characterized by severe disabling fatigue lasting for more than 6 months associated with physical and mental disturbances such as headache, arthralgia, myalgia, memory impairment, sore throat and tender lymph nodes. The exact pathogenesis is still unknown. Several models were proposed to explain its etiology including chronic infection, endocrine dysfunction, autonomic imbalance, depression, decreased immunity states and an aberrant reaction to infection. No convincing evidence was found to support any of the suggested pathogenic mechanisms. The current concept is that CFS pathogenesis is a multi factorial condition in which an infective agent cause an aberrant immune response characterized by a shift to Th-2 dominant response. When the response fails to be switched-off, a chronic immune activation occurs and clinically expressed as the symptomatology of CFS. Vaccinations are used in order to stimulate the immune system to induce a persistent immunity against the favorable antigens. Several syndromes that contain chronic fatigue as one of their symptoms, such as "Gulf war syndrome" and macrophagic myofasciitis were related to vaccinations. Can vaccinations induce the aberrant immune response of CFS? Little is known about this issue. There are some reports on CFS occurring after vaccination, but few prospective and retrospective studies failed to find such an association. A working group of the Canadian Laboratory Center for Disease Control (LCDC) that was founded in order to examine the suspected association between CFS and vaccinations concluded that there is no evidence that relates CFS to vaccination. Further studies are requested to examine this issue since it is very conceivable that if infection can lead to CFS, vaccination may also lead to it in the same immune-mediated pathogenesis.
KW - Chronic fatigue syndrome
KW - Infection
KW - Th-2 immune response
KW - Vaccination
JO - Autoimmunity
JF - Autoimmunity
Appel S, Chapman J, Shoenfeld Y. Infection and vaccination in chronic fatigue syndrome: Myth or reality? Autoimmunity. 2007 Feb 1;40(1):48-53. https://doi.org/10.1080/08916930701197273


Thanks to the repeated refusal of a pair of worse-than-useless gammas, namely, Haxo Angmark and Philip George, to accept the fact that their unsolicited contributions to the discourse were determined to be undesirable, I have permanently instituted comment moderation here.
This shouldn't have much of an effect on anyone but them, other than a slight delay in your comments appearing, but it means that the moderators no longer have to waste time hunting down and deleting comments from banned commenters.
If you're a gamma, it may help to understand that this total inability to respect the social order is precisely the reason why people not only hate you, but hate everyone who even reminds them of you. In a better, more just world, gammas would simply be taken out and shot after their high school graduation given their proven inability to function in adult society.


text:
Clinicopathological significance of nuclear factor-κB activation in hepatocellular carcinoma
Hideki Yokoo, Jun Yasuda, Kazuaki Nakanishi, Makoto Chuma, Toshiya Kamiyama, Satoru Todo, Setsuo Hirohashi, Michiie Sakamoto
Aim: Nuclear factor-κB (NF-κB) is a critical signaling mediator in inflammation, apoptosis resistance and oncogenesis. It has been reported that NF-κB is activated in several cancers, including hepatocellular carcinoma (HCC). Studies of genetic disruptions in mice also suggest that NF-κB plays critical roles in hepatocarcinogenesis. The aim of the present study is to characterize NF-κB activation and correlate it with the degree of malignancy in HCC. Methods: To examine the correlation between the positivity of the nuclear p50 subunit and HCC recurrence, we analyzed immunostaining of the NF-κB p50 subunit in two groups of HCC samples with known prognosis and Akt phosphorylation status: 49 patients showing early recurrence within 6months (group A) and 50 patients who were recurrence-free for at least for 3years (group B). Results: In group A, positive nuclear staining of p50 was shown in 18 cases (36.7%), whereas only one case (2.0%) in group B had positive nuclear staining of p50 (P=2.48839×10-5). This suggests a positive relationship between nuclear p50 and early recurrence and advanced HCC in humans. The presence of phosphorylated Akt correlated with nuclear staining of p50 in HCCs in group A (R2=0.213, P<0.001). Conclusion: Our results indicate that nuclear staining of p50 was clearly associated with early recurrent HCC, and the Akt pathway might play a role in NF-κB activation in a subset of early recurrent HCC.
Hepatology Research
Staining and Labeling
Inflammation Mediators
Nuclear factor-κB
Phosphorylated Akt
Yokoo, H., Yasuda, J., Nakanishi, K., Chuma, M., Kamiyama, T., Todo, S., ... Sakamoto, M. (2011). Clinicopathological significance of nuclear factor-κB activation in hepatocellular carcinoma. Hepatology Research, 41(3), 240-249. https://doi.org/10.1111/j.1872-034X.2010.00758.x
Clinicopathological significance of nuclear factor-κB activation in hepatocellular carcinoma. / Yokoo, Hideki; Yasuda, Jun; Nakanishi, Kazuaki; Chuma, Makoto; Kamiyama, Toshiya; Todo, Satoru; Hirohashi, Setsuo; Sakamoto, Michiie.
In: Hepatology Research, Vol. 41, No. 3, 03.2011, p. 240-249.
Yokoo, H, Yasuda, J, Nakanishi, K, Chuma, M, Kamiyama, T, Todo, S, Hirohashi, S & Sakamoto, M 2011, 'Clinicopathological significance of nuclear factor-κB activation in hepatocellular carcinoma', Hepatology Research, vol. 41, no. 3, pp. 240-249. https://doi.org/10.1111/j.1872-034X.2010.00758.x
Yokoo H, Yasuda J, Nakanishi K, Chuma M, Kamiyama T, Todo S et al. Clinicopathological significance of nuclear factor-κB activation in hepatocellular carcinoma. Hepatology Research. 2011 Mar;41(3):240-249. https://doi.org/10.1111/j.1872-034X.2010.00758.x
Yokoo, Hideki ; Yasuda, Jun ; Nakanishi, Kazuaki ; Chuma, Makoto ; Kamiyama, Toshiya ; Todo, Satoru ; Hirohashi, Setsuo ; Sakamoto, Michiie. / Clinicopathological significance of nuclear factor-κB activation in hepatocellular carcinoma. In: Hepatology Research. 2011 ; Vol. 41, No. 3. pp. 240-249.
@article{f3c94b5d007046d68b84c2f94bf11099,
title = "Clinicopathological significance of nuclear factor-κB activation in hepatocellular carcinoma",
abstract = "Aim: Nuclear factor-κB (NF-κB) is a critical signaling mediator in inflammation, apoptosis resistance and oncogenesis. It has been reported that NF-κB is activated in several cancers, including hepatocellular carcinoma (HCC). Studies of genetic disruptions in mice also suggest that NF-κB plays critical roles in hepatocarcinogenesis. The aim of the present study is to characterize NF-κB activation and correlate it with the degree of malignancy in HCC. Methods: To examine the correlation between the positivity of the nuclear p50 subunit and HCC recurrence, we analyzed immunostaining of the NF-κB p50 subunit in two groups of HCC samples with known prognosis and Akt phosphorylation status: 49 patients showing early recurrence within 6months (group A) and 50 patients who were recurrence-free for at least for 3years (group B). Results: In group A, positive nuclear staining of p50 was shown in 18 cases (36.7{\%}), whereas only one case (2.0{\%}) in group B had positive nuclear staining of p50 (P=2.48839×10-5). This suggests a positive relationship between nuclear p50 and early recurrence and advanced HCC in humans. The presence of phosphorylated Akt correlated with nuclear staining of p50 in HCCs in group A (R2=0.213, P<0.001). Conclusion: Our results indicate that nuclear staining of p50 was clearly associated with early recurrent HCC, and the Akt pathway might play a role in NF-κB activation in a subset of early recurrent HCC.",
keywords = "Clinical significance, Hepatocellular carcinoma, Immunohistochemistry, Nuclear factor-κB, Phosphorylated Akt",
author = "Hideki Yokoo and Jun Yasuda and Kazuaki Nakanishi and Makoto Chuma and Toshiya Kamiyama and Satoru Todo and Setsuo Hirohashi and Michiie Sakamoto",
doi = "10.1111/j.1872-034X.2010.00758.x",
journal = "Hepatology Research",
publisher = "Wiley-Blackwell Publishing Ltd",
T1 - Clinicopathological significance of nuclear factor-κB activation in hepatocellular carcinoma
AU - Yokoo, Hideki
AU - Yasuda, Jun
AU - Nakanishi, Kazuaki
AU - Chuma, Makoto
AU - Kamiyama, Toshiya
AU - Todo, Satoru
AU - Hirohashi, Setsuo
AU - Sakamoto, Michiie
N2 - Aim: Nuclear factor-κB (NF-κB) is a critical signaling mediator in inflammation, apoptosis resistance and oncogenesis. It has been reported that NF-κB is activated in several cancers, including hepatocellular carcinoma (HCC). Studies of genetic disruptions in mice also suggest that NF-κB plays critical roles in hepatocarcinogenesis. The aim of the present study is to characterize NF-κB activation and correlate it with the degree of malignancy in HCC. Methods: To examine the correlation between the positivity of the nuclear p50 subunit and HCC recurrence, we analyzed immunostaining of the NF-κB p50 subunit in two groups of HCC samples with known prognosis and Akt phosphorylation status: 49 patients showing early recurrence within 6months (group A) and 50 patients who were recurrence-free for at least for 3years (group B). Results: In group A, positive nuclear staining of p50 was shown in 18 cases (36.7%), whereas only one case (2.0%) in group B had positive nuclear staining of p50 (P=2.48839×10-5). This suggests a positive relationship between nuclear p50 and early recurrence and advanced HCC in humans. The presence of phosphorylated Akt correlated with nuclear staining of p50 in HCCs in group A (R2=0.213, P<0.001). Conclusion: Our results indicate that nuclear staining of p50 was clearly associated with early recurrent HCC, and the Akt pathway might play a role in NF-κB activation in a subset of early recurrent HCC.
AB - Aim: Nuclear factor-κB (NF-κB) is a critical signaling mediator in inflammation, apoptosis resistance and oncogenesis. It has been reported that NF-κB is activated in several cancers, including hepatocellular carcinoma (HCC). Studies of genetic disruptions in mice also suggest that NF-κB plays critical roles in hepatocarcinogenesis. The aim of the present study is to characterize NF-κB activation and correlate it with the degree of malignancy in HCC. Methods: To examine the correlation between the positivity of the nuclear p50 subunit and HCC recurrence, we analyzed immunostaining of the NF-κB p50 subunit in two groups of HCC samples with known prognosis and Akt phosphorylation status: 49 patients showing early recurrence within 6months (group A) and 50 patients who were recurrence-free for at least for 3years (group B). Results: In group A, positive nuclear staining of p50 was shown in 18 cases (36.7%), whereas only one case (2.0%) in group B had positive nuclear staining of p50 (P=2.48839×10-5). This suggests a positive relationship between nuclear p50 and early recurrence and advanced HCC in humans. The presence of phosphorylated Akt correlated with nuclear staining of p50 in HCCs in group A (R2=0.213, P<0.001). Conclusion: Our results indicate that nuclear staining of p50 was clearly associated with early recurrent HCC, and the Akt pathway might play a role in NF-κB activation in a subset of early recurrent HCC.
KW - Clinical significance
KW - Hepatocellular carcinoma
KW - Immunohistochemistry
KW - Nuclear factor-κB
KW - Phosphorylated Akt
U2 - 10.1111/j.1872-034X.2010.00758.x
DO - 10.1111/j.1872-034X.2010.00758.x
JO - Hepatology Research
JF - Hepatology Research

redpajama_set_name: RedPajamaCommonCrawl


A stone that symbolizes love, the heart, and its protection. It is loved for its soft colour that is so easy to wear. Rose quartz is a stone that brings a lot of good; that's why we like to keep it close to us.
Gold-plated chain necklace with a semi-precious stone pendant made of rose quartz. It has a gold clasp.
This stone symbolizes love—universal love. It brings calm and wellness to the heart and spirit: tenderness, softness, serenity, and self-confidence. It is truly the stone of artistic expression, and connects you to your heart, your soul. It is said that it helps heal the wounds of the soul.
Our jewellery pieces are all handmade in Quebec. We put a lot of care into choosing high quality materials based on their price. You can easily wear them every day, but please avoid submerging them in water to help the gold plating last longer.


text:
Grand Challenges for Social Work
Social progress powered by science
From stopping family violence to closing the health gap and ending homelessness, the most pressing issues facing America today have one thing in common: a social factor.
To galvanize social work expertise, education, research and practice, the American Academy of Social Work and Social Welfare launched the Grand Challenges for Social Work in 2016. This groundbreaking initiative champions social progress powered by science—and provides a structure to explore innovative approaches, build unique partnership and work across sectors to strengthen the social fabric in 12 key areas. "This is an opportunity to catalyze the profession in a way that's never been done before," says Richard Barth, president of the American Academy of Social Work and Social Welfare, which oversees this national effort. (Read the Wikipedia profile here.)
The School of Social Work has been at the center of the Grand Challenges initiative since the beginning, when the idea grew out of a 2012 gathering co-sponsored by Dean Uehara. In recognition of her contributions, the AASWSW named Uehara as an inaugural honorary fellow. In the same year, she was inducted as a regular fellow, becoming the first person to hold both designations within the academy. UW School of Social Work faculty is also taking the lead on topics ranging from harnessing technology for social good to reducing the income-disparity gap. The School is deploying the "ensuring healthy development for all youth" challenge in Southeast and Central Seattle, making a real and measurable impact through its Communities in Action initiative.
Dean Uehara fosters international understanding of Grand Challenges
In Sept. 2018, Dean Eddie Uehara addressed an enthusiastic international audience on Grand Challenges for Social Work at the Joint Social Work Education and Research Conference, held Sept. 3-4 at Canterbury Christ Church University, England. The conference provided a platform to discuss Grand Challenges progress and to formalize an international approach. The U.S. Grand Challenges initiative is now in formal partnership with the UK social work Grand Challenges effort.
UW lends support to national initiative
In June 2018, the UW Office of the Provost announced that it will fund graduate student research in the Grand Challenges topic areas, signaling the University's support for the School's leadership role in the national effort. The School will match the $25,000 provided by the provost in order to fund $50,000 in financial awards to competitively selected social work graduate students whose dissertation or thesis focuses on one of the 12 Grand Challenges.
Watch the Grand Challenges for Social Work video
Sign up for the Grand Challenges Social Work email list
Find your challenge
Individual and Family Well-being
Ensure healthy development for all youth
Close the health gap
Stop family violence
Advance long productive lives
Stronger Social Fabric
Eradicate social isolation
End homelessness
Create social responses to a changing environment
Harness technology for social good
Just Society
Promote smart decarceration
Reduce extreme economic inequality
Build financial capability for all
Achieve equal opportunity and justice
Grand Challenges for Social Work and Society gives readers an overview of the dozen social issues, providing ideas for directions to take and ways to get involved.


text:
Researchers Suggest New Disease Model May Some Day Lead To Effective Drugs ForHIV-Associated Dementia
CHICAGO--Researchers have long believed that macrophages, the scavenger cells of the immune system, do not divide. They emerge from the bone marrow as monocytes, circulate in the bloodstream for three days, and then migrate into tissue, where they resume a variety of functional roles.
But in a plenary session of the Neuroscience of HIV Infection meeting here today, June 5, a UC San Francisco researcher proposes not only that these cells can divide under certain abnormal circumstances, producing identical daughter cells, but that when they do so they proliferate, affect neighboring cells and, as a result, in some cases cause disease.
While focusing on his latest findings regarding the proposed role of macrophage proliferation in AIDS dementia, Michael McGrath, MD, PhD, a UCSF associate professor of laboratory medicine, laid out a paradigm he calls "sequential pathogenesis," a process in which, he suggested, macrophages may be the key player in numerous cell-proliferation diseases, including AIDS-related lymphoma and dementia.
"Based on these studies, my colleagues and I have readjusted our thinking regarding some aspects of macrophage function," said McGrath. "We're suggesting that these replicating macrophages may be the cornerstone of some human diseases."
According to the theory of "sequential pathogenesis," HIV or, perhaps even some other genetic element, integrates itself into the genome of macrophages, next to one of several cancer-causing genes, causing these so-called oncogenes to be activated. The oncogenes then prompt macrophages to begin expressing growth factors that, in turn, trigger the proliferation of other macrophages and other cell types involved in a range of disease conditions.
McGrath and his colleagues, including Brian Herndier, UCSF associate professor of pathology, said that they have identified three different macrophage-associated oncogenes, c-fes and platelet derived growth factor A and B, as being involved in different forms of HIV-associated degenerative and proliferative diseases.
"Our theory is that, depending on where HIV integrates itself into the macrophage genome--thus determining which oncogene is turned on inappropriately--there will be an increased risk for development of cancer or dementia," said McGrath.
McGrath has previously reported elements of his paradigm in Cancer Research (1994), regarding HIV integration in HIV-associated lymphomas; in JAIDS (1995) regarding HIV-associated Kaposi's Sarcoma; and in Lancet (1997) regarding a blood test that identified elevated levels of activated macrophages in AIDS dementia.
Today, he presented data supporting a new model that he says suggests that AIDS dementia may be, in part, the result of a process involving HIV-infected macrophage division. HIV-infected macrophages have long been known to appear in large numbers in the brains of HIV-infected patients. Macrophages make many different factors harmful to the brain, and conventional strategies have sought to block the factors, unsuccessfully.
Now McGrath reports that, in AIDS dementia patients, HIV may integrate itself into the macrophage genome next to the platelet derived growth factor B oncogene. "We are showing proliferating macrophages in the brain expressing the PDGF-B product, and demonstrating that they are doing so in an area where there are increased numbers of astrocytes [cells that proliferate in response to the destruction of nearby neurons.]"
McGrath also reported that researchers have identified a class of DNA-interacting drugs related to polyamines that, he said, could be potential candidates for treatment of AIDS dementia.
"In a preliminary study, a single dose of the drug," he said, "killed dividing macrophages, and thus removed the production of substances that kill brain cells in vitro. By contrast, cytotoxan, a standard cancer chemotherapy agent, had little effect on these cells."
The technology regarding this newly described class of macrophages (therapeutic, prognostic and diagnostic) is being developed by SLIL Biomedical Corp., of San Mateo, CA.
University of California has received patents on the full technology platform, which includes potential diagnostic blood tests and drug therapies. McGrath and Herndier are chief scientific consultants to SLIL and principal founders of the company's Biomedical Analysis division.
Notes to media:
To arrange an interview with Michael McGrath, MD, PhD, contact Jennifer O'Brien in the UCSF News Office, at 415/476-2557.
For information on SLIL Biomedical Corp., contact Carol Melis or Mike Jackman at 650/342-5686.
Two lay-oriented graphic images of "sequential pathogenesis," can be accessed at: http://www.pubaffr.ucsf.edu/news/photos/0605path.html
Shiramizu BS, Herndier BG and McGrath MS. Identification of a common clonal HIV integration site in HIV virus-associated lymphomas. Cancer Research 54:2069-2072; 1994
McGrath MS, Shiramizu B, Herndier B. Identification of a clonal form of HIV in early Kaposi's sarcoma: evidence for a novel model of oncogenesis, "sequential neoplasia". JAIDS 8:379-385; 1995
Pulliam L, Gascon R, Stubblebine M, McGuire D, McGrath MS. Unique monocyte subset in patients with AIDS dementia. Lancet 349:692-695; 1997
University of California - San Francisco


Find local bargains in and near Balmaha (Central).
The listings below are an automated feed from Ebay for the village "Balmaha".
View more listed items with "Balmaha" in the title. (Problem with any of these listings? Report it to us here).


We are offering our clients a wide show of Flame Arrestor for welding Equipment. Made utilizing amazing material, these arresters are in coupled with global quality principles. Accessible in a range of details, these arresters are widely relevant in welding and electrical supplies.hese Cartridge Filters are cleanable and reusable resulting in reduced operation cost.Being a quality centric firm we are dedicatedly engaged in offering our clients Sinter Bronze Flame Arrestor For Welding Equipments with utmost quality. Our offered product is manufactured using high quality raw material and advanced technology in adherence with set industry norms.. This range is designed specially with staggered dimpling on filtering surface which allows unrestricted air flow along with pulse cleaning at the ends of the pleats. Moreover, we offer this product to our customers at affordable prices.
Looking for Flame Arrestor for Electrical Equipment ?


This thru axle is only suitable for Suntour forks that use QLoc locking system. This is set may not be compatible with other forks.
Purchase includes one black 15mm Pitlock thru-axle, one thread socket, and one PIT-key. If you need additional keys, please order additional keys here.
Unless you specify otherwise, we will ensure that the additional keys you order will match the coded set you're given.


Aran cucine, Magistra - Luxury Topics luxury portal: Fashion, Style, Trends, Collection 2018.
Authenticity, unique and virtuous manufacturing, tradition: handicraft ability is an important value for Aran Cucine, ambassador brand for Made in Italy throughout the world, able to offer with the Magistra model a kitchen with a materic touch, crafted with tailored details.
Born from the encounter between contemporary taste, modern and warmth, typical from old day's houses, Magistra is a kitchen which 'tastes' familiar, conceived as the real core of the home, gathering centre, sharing point.
For this reason Aran Cucine has also developed, together with the traditional base cabinets and wall units, a series of islands, wall shelves systems, glass doors, hanging shelves, as they were an extension of the kitchen itself towards the living area.
Developed in several versions, Magistra is available in many finishes, each of whom, combined with refined details, is able to give a precise touch of style to the environment.
Where compositions in Pickled clay lacquered ash and White lacquered ash, with their glass inserts fit harmoniously in the most modern environments, the version with ancient metal handle recalls a taste which is more vintage.
The finish White lacquered ash, with c-channel installed on the doors, meets the demand of a contemporary taste, able to 'warm up' even the most minimal design.
And, finally, where the Durmast painted Ash with nickeled brass bound glass takes us back to a more country, and genuinely familiar environment, the finish Titanium Veneered Lacquered ash, embellished by silver inserts, and marble worktops, shows us a more defined and confident personality, towards a timeless elegance.
A various and versatile model, Magistra, is a real example of how master handicraft characterises Aran cucine. A kitchen 'magistrally' executed, born from a tradition which is able to look ahead towards future and to meet contemporary demands.


text:
What Happens to Education Spending if the Budget Stays in a Holding Pattern
Your Education Road Map
Politics K-12®
ESSA. Congress. State chiefs. School spending. Elections. Education Week reporters keep watch on education policy and politics in the nation's capital and in the states. Read more from this blog.
By Andrew Ujifusa — March 06, 2017 4 min read
Right now, the federal budget is flying in circles. It's operating on a "continuing resolution" through April 28 that essentially holds fiscal year 2017 spending levels at their fiscal 2016 amounts. Trump recently released a very broad outline of his spending priorities for fiscal 2018 that includes a $54 billion cut from domestic agencies—fiscal 2018 starts in October—although we still don't know how that 10 percent cut in non-defense discretionary spending would specifically impact the U.S. Department of Education.
But where does that leave fiscal 2017 in terms of education spending? And what happens if Congress decides to apply that continuing resolution to the rest of fiscal 2017 through September? With each passing day, that looks increasingly likely.
Below, we examine how a few programs in the Every Students Succeeds Act would be affected if Congress approves a continuing resolution for the rest of the fiscal 2017.
Here's one important thing to keep in mind: Although a continuing resolution would keep funding at current levels, Congress can adjust what's in such a resolution, through what are called "anomalies" in federal budget lingo. In general, it's very likely that lawmakers will attempt to square what's in the continuing resolution with what's in ESSA. But what that process looks like, and how closely any such resolution ultimately matches ESSA in terms of funding levels, remains to be seen.
"The most difficult part is then deciding the numbers," said Joel Packer, the former executive director of the Committee for Education Funding, who added that overall funding levels for the U.S. Department of Education could also be in play during any continuing resolution. There are a lot of moving parts in the process, Packer stressed.
Let's first look at Title I and the Obama-era School Improvement Grants. SIG is no longer authorized under ESSA. However, the law does require states to set aside 7 percent of their Title I funding for school improvement activities. That's an increase from the 4 percent optional state set-aside under the previous version of federal K-12 law. In budget terms, the money for SIG is effectively migrating over to that increased Title I set-aside at the state level.
But since the continuing resolution as it stands now would keep Title I funding flat, it could effectively amount to a cut in Title I funding that's available for districts. Would Congress decide to make up this funding to districts? If so, by how much? We won't have an answer until we know what's in any continuing resolution.
It's also important to note that the vast majority of that Title I set-aside money ultimately will end up going to districts anyway for school improvement purposes. States will have discretion over how that money goes out and set the priorities for how it gets spent. So it's not as if the states will simply swim in that cash and keep it from districts. Still, that's money that won't be going into the typical Title I formulas districts count on.
The Big Block Grant
Title IV (or what we like to call "the big block grant") won't exist if the current continuing resolution is rolled over. That's because even though it's authorized in the Every Student Succeeds Act, there's no funding for it in the current continuing resolution. Congress would have to create an adjustment in the resolution—the "anomaly" referred to above—in order to pay for what's in Title IV.
There's a diverse coalition of groups pushing for (and pushing for substantial funding for) the Title IV grants, which are designed to fund the well-rounded education of students, a priority in ESSA. However, in 2016 budget bills floated last summer, Congress fell far short of funding Title IV at the $1.6 billion authorized for it in ESSA—so did the Obama administration's budget proposal, for that matter.
So if, through one of those anomalies, the continuing resolution does fund the Title IV block grant, how much will lawmakers give it? The $1 billion House lawmakers proposed? Or the $300 million the Senate wanted to provide? Something in between, or more, or less? Again, we won't know until we see the continuing resolution, assuming there is one.
New LEARN Grant
Under the resolution, the Literacy Education for All, Results for the Nation (LEARN) program in Title II that covers teacher training and prepration also doesn't get funded, DeSchryver said. LEARN was originally a bill from Sen. Patty Murray, D-Wash., that got folded into ESSA. Through competitive grants, LEARN would fund a state literacy plan, professional development for teachers in literacy skills, and programs to address specific populations of students in literacy instruction, such as English-language leraners.
ESSA authorized $160 million for LEARN, but unless lawmakers were to tweak the resolution to fund it, LEARN wouldn't get a dime. "It doesn't exist, absent some [change] in the CR," said David DeSchryver, a senior vice president at Whiteboard Advisors.
Also, remember that the current continuing resolution lasts until April 28, so we might not know for several more weeks how the rest of fiscal 2017 will unfold.
And what's a final catch in this whole process? Unlike in a traditional budget process that includes things like hearings, Packer said, putting "anomalies" into a continuing resolution isn't transparent.
"It's all done completely in the dark and in secret," Packer said of what changes get made to continuing resolutions.
Follow us on Twitter at @PoliticsK12.
Andrew Ujifusa
Andrew Ujifusa was an assistant editor who covers national education policy and politics.
Federal Budget Congress
Protesters gather for the March For Our Lives rally in Detroit, among the demonstrations against gun violence held on the heels of recent mass shootings in Buffalo, N.Y., and Uvalde, Texas.
KT Kanazawich for Education Week
Federal What Educators Need to Know About Senators' Bipartisan Deal on Guns, School Safety
Evie Blad, June 13, 2022
U.S. Secretary of Education Miguel Cardona, is seen during a White House event on April 27. The following day, he defended the Biden administration's budget proposal on Capitol Hill.
Susan Walsh/AP
Federal Lawmakers, Education Secretary Clash Over Charter School Rules
Mark Lieberman, April 28, 2022
President Joe Biden delivers his first State of the Union address to a joint session of Congress, with Vice President Kamala Harris and House Speaker Nancy Pelosi in attendance.
Sarahbeth Maney/The New York Times via AP
Federal 7 Takeaways for Educators From Biden's State of the Union
Evie Blad, March 2, 2022
Every Student Succeeds Act Opinion 20 Years Ago, NCLB Kinda, Sorta Worked. That's the Problem
Rick Hess, October 3, 2022


Nowadays, you can find that there is a lot of people who are going through terrible situations that are out of their hands. However, there are many organizations and groups that create ways in which others can help them.
Thanks to today's technology, it is easier to help others with whatever is in their possibilities. In fact, there are so many options and ways to do it that you can choose, from donating online to searching for events close to you where you can have an active participation in the process.
If your goal is to help others, you can participate in many social events. Here we will show you some of these events.
Kids get to dress you up as foolish as they want and raise awareness on sustainable clothing and poverty.
Spent the whole month of November without shaving your mustache to raise awareness on men's health issues.
Create an outfit that includes colorfully decorated customized underwear and show it off in public in order to fund breast cancer research.
Use social media to spread the word on some of the world's biggest issues and win nice goodies in the process.
Homeless people get to participate in an activity that helps them integrate into society and show off their skills. Really heartwarming.
Donate blood and feel like a cool vampire fighter in the process.
These events raise money either to create awareness regarding health issues or to fight against poverty. They are the best option to help people around the globe.
Worldwide Vegan Bake Sale.Show off your delicious vegan recipes and raise awareness against animal cruelty at the same time.
Get to save Gorillas by dressing up as one and running through a marathon. Have fun while creating awareness against animal cruelty and raise funds for causes related to these objectives.
If you prefer protecting people, animals, the environment or all together, then you will want to try to actively participate in making a change in the world. The most important thing is that you actually start doing something. And little by little, there will be a lot of results.


text:
John Oliver on Vaccines..."He got it dead wrong."
Medical journalist and Vaxxed producer, Del Bigtree, sums up John Oliver's recent HBO episode on vaccines beautifully with the statement, "He got it dead wrong." Unfortunately, Mr. Oliver delivered quite a bit of misleading information to his viewers. In the HighWire video below, Del, responds to the comedian/talk show host, point by point, setting the facts straight.
It's unfortunate that Mr. Oliver didn't talk with Del first or research beyond the CDC website, before regurgitating many of the same "safe and effective" sound bytes we hear over and over again from the vaccine industry and pro-vaccine advocates. Take time to watch. You'll learn a lot.
Vaccine injury and death are real and frequent. Children are harmed and families are left to pick up the pieces of their shattered lives. Perhaps comedians like Mr. Oliver should stop trying to turn this very serious topic into a laughing matter; or at the very least, become better informed, at which point they would find out for themselves, that the harm and heartache vaccines can and do cause are just not funny at all.
Below is the full Last Week Tonight with John Oliver episode, for those who care to watch. Scroll down further for other responses to Mr. Oliver; for the IOM (Institute of Medicine) report and other items that Del references; and also for the video "Measles Back in the Days Before the Marketing of Vaccines" which includes excerpts from "The Brady Bunch" measles episode and two other well loved TV shows from 1950s and 1960s.
Popular family TV shows from the 1950s and 60s about Measles:
John Oliver, You're Wrong on Vaccines
John Oliver, you unfunny schmuck...
VAERS (Vaccine Adverse Event Reporting System)
Adverse Effects of Vaccines, Evidence and Casualty -Institute Of Medicine
Vaccine Ingredients
Vaccine Package Inserts
2017 Childhood Vaccine Schedule


Authorities canceled the Amber Alert for 12-year-old Wyoming boy Zane Leo Armour. The alert had been issued Tuesday morning.
Armour was last seen getting into a black crossover vehicle, possibly a Chevrolet, according to the initial alert. That sighting occurred at 1 Lonebear Lane in Ethete.
Authorities described Armour as a non-verbal autistic juvenile. He is 4 feet, 7 inches tall and weighs 110 pounds, with brown hair and brown eyes.


text:
Discover more:Gaana, Gaana.com, Internet, Music, News, Times Internet
Gaana Claims To Have 1M Registered Users; 100M Minutes Of Use In 2012
Times Internet's online music streaming service Gaana.com has claimed that people have spent more than 100 million minutes listening to music on the portal in 2012, registering a growth of more than 500% year-on-year. Usage Metrics: The service claims to have registered a 71% growth in the number of daily users in 2012 and witnessed a total one million registrations as of last week, with 68% of the users being 30 years or younger. However, the company didn't disclose the number of active users or the total number of unique visitors on the portal. According to the Times Internet website, Gaana had 2.3 million unique visitors and had registered 50 million pageviews as of April 2012, according to Comscore metrics. Usage Trends: Times Internet claimed that Gaana registered 11 pageviews per visit, up from 5 pageviews per visit in 2011 and users spent 21 minutes per visit as compared to 7 minutes per visit in 2011. Browser-wise, the company claimed that Google Chrome accounted for 41.13% of Gaana users, followed by Firefox which accounted for 24.02% users, and Internet Explorer which accounted for 16.19% users. Others in the list include Safari (2.75%) and Opera (2.16%). Top Song and Top Album: Times Internet stated that Pani Da rang song from Vicky Donor was the highest played song on Gaana, clocking over 3.57 million listens in 2012, while Cocktail was the highest played album of the year, clocking over 6.4 million listens. The company also claimed that 5 million users had tuned into Gaana Radio, since it was…


text:
<?php

// No direct access.
defined('_HZEXEC_') or die();

Toolbar::title(Lang::txt('Solr Search: Overview'));
Toolbar::custom('optimize', 'save', 'optimize', 'COM_SEARCH_SOLR_OPTIMIZE', false);
Toolbar::spacer();
Toolbar::preferences($this->option, '550');
$this->css('solr');
$option = $this->option;

Submenu::addEntry(
	Lang::txt('Overview'),
	\Route::url('index.php?option='.$option.'&task=configure'),
	true
);
Submenu::addEntry(
	Lang::txt('Searchable Components'),
	\Route::url('index.php?option='.$option.'&task=display&controller=searchable')
);
Submenu::addEntry(
	Lang::txt('Index Blacklist'),
	\Route::url('index.php?option='.$option.'&task=manageBlacklist')
);
?>

Solr Status

Last Document Insert: <?php echo $this->lastInsert; ?>

Mechanism: <?php echo ucfirst($this->mechanism); ?>

						<?php if ($this->status === true) : ?>

The search engine is responding.

Last insert was <?php echo $this->lastInsert; ?>

						<?php else : ?>

<?php echo Lang::txt('COM_SEARCH_NOT_RESPONDING'); ?>

<?php echo Lang::txt('COM_SEARCH_CHECK_CONFIG'); ?>

						<?php endif; ?>

	<form action="<?php echo Route::url('index.php?option=' . $this->option); ?>" method="post" name="adminForm" id="adminForm">
		<input type="hidden" name="option" value="com_search" />
		<input type="hidden" name="controller" value="solr" />
		<input type="hidden" name="task" value="searchIndex" autocomplete="" />
		<?php echo Html::input('token'); ?>
	</form>

	<?php if (isset($this->queueStats) && false): ?>

<?php echo Lang::txt('COM_SEARCH_QUEUE_STATUS'); ?>

						<?php echo Lang::txt('COM_SEARCH_QUEUE_LAST_SERVICE') . ':' . Date::of($this->queueStats['modified'])->relative(); ?>

						<?php echo Lang::txt('COM_SEARCH_QUEUE_AVERAGE_SERVICE') . ':' . $this->queueStats['serviceTime'] . 'minutes'; ?>

	<?php endif; ?>

redpajama_set_name: RedPajamaGithub


I could sit here for hours and write about my favourite and most amazing educational moments from the days of doing GCSEs and A-Levels; but that is not the first thing that sprung to mind when I think of education. For I have never really seen school as just an educational institute, instead, it scarily became a home away from home, those white walls saw me for who I truly was; both at my highest and lowest points. The education I received from inspirational members of staff enabled me to develop as a human being; and to put it bluntly – they helped me to still be here today.
We must continue to progress with our understanding and treatment of those that struggle with mental illness.
The work that teachers and other support staff do in schools is good (from my experience) but students can be very limited to who they are professionally able to confide in due to safeguarding issues and/or lack of training.
It is fine to put designated staff in charge of those students struggling, but you cannot choose to bond with those you are forced to. The deep and emotional thoughts and feelings that students are struggling to manage are not that easy to convey, especially if it is to someone as scarily official as a 'school counsellor'.
The main question I would like to ask the education boards is: why do we learn so much about how the body works physically in both biology and physical education but unless you opt to take psychology in your later teenage years, you are rarely taught anything about the dangers of mental health?
We are not progressing fast enough! We need more training for teachers and other support staff in spotting early signs of mental illness, along with lessons like sexual education lessons but based around mental health such as depression, anxiety and bipolar.
One of the core lessons we are taught throughout our education is language. Yet students do not realise that aspects of their language can shape their understanding of mental illness - for example, if a student was to be given maths homework and their response was "OMG, Maths homework! I am so depressed!". Depression and the term depressed is not an expression for sadness or despair. It is a long term and terrifyingly isolating illness. I am not saying that everyone who has ever misused the word is a terrible person with a lack of understanding, but I would like them to be more aware of the language being used. If we were to do the same with our physical pain we would be called a hypochondriac for saying something like "OMG I've been shot", after having some stomach cramps.
I must say a big thank you to the staff at my old school Q3 Academy. In particular an excellent PE teacher and member of senior management - who not only inspired me to progress to University but also helped me so much with my mental health. She took me from rock bottom to leaving school with my head held high. I hope everyone can have at least one member of staff at their school to guide them to a bright future.
If you are currently a student, please do not be afraid to speak out to someone, they are here to help and you are not a burden. I decided in my final year to try and be a lot more open with my teacher and it worked! We would go for walks around school and have regular catch ups. It doesn't have to be a big uncool deal to talk to a teacher about your feelings, I actually felt it was the best way. A teacher is someone you know, but do not have a 'pressured' bond (like family and friends), making them the perfect people to talk to.
They are not magicians but mostly comedians who are good at getting that smile from you when you need a boost in the day!
If you are a parent or anyone currently outside the education system - think back to your days in education, it is arguably the most defining point of your life.
If you are a teacher or anyone that works in a school/education setting. I would like to say thank you. You lovely lot don't get the appreciation you deserve, you picked us up from our early years of life and dropped us off at the doors of our employers. The tears, tantrums, smiles, laughs... you've seen and heard it all, yet you are still there every day with a good morning and usually a cup of coffee. So thank you, and when you're struggling after a tough, long day in the classroom please remember you are needed and wanted.


How To Build A Storage Bench Seat - Storage benches give the perfect remedy to your own storage worries. These functional items of furniture can be put inside unused spaces within the home, from the particular lounge to the bathroom. You can find storage benches in a range of sizes in order to suit the accessible space you may have inside any provided room. Actually a corner may accommodate a bench, since you can now buy corner benches for these underutilized areas.
Storage benches are very flexible as well as practical as a person can store several items within the furniture. Each room within the home offers its storage difficulties where these just isn't enough space for every thing. Therefore a storage bench can be used inside just concerning every room in the home since an additional piece of furniture to store your own items to provide a chaos free home.
For Storage Bench, You can find many ideas on the topic Storage Bench How, Bench, Seat, To, Build, Storage, A, and many more on the internet, but in the post of How To Build A Storage Bench Seat we have tried to select the best visual idea about Storage Bench You also can look for more ideas on Storage Bench category apart from the topic How To Build A Storage Bench Seat.
This post published on Saturday, September 9th, 2017 . Read Kitchen Benches With Storage or find other post and pictures about Storage Bench.


text:
#include <linux/config.h>
#include <asm/io.h>
#include <asm/hs7751rvoip/hs7751rvoip.h>

extern unsigned int debug_counter;

void debug_led_disp(void)
{
	unsigned short value;

	value = (unsigned char)debug_counter++;
	ctrl_outb((0xf0|value), PA_OUTPORTR);
	if (value == 0x0f)
		debug_counter = 0;
}


Russell Reserve Lord's Bay is just outside the traditional GBLT catchment area in Severn Township. It is however representative of the area, and includes extensive shallow and coastal wetlands. The entire Lord's Bay is a large shallow marsh with submerged and floating aquatic vegetation, providing ideal habitat for turtles and fish, including feeding and spawning grounds. The islands include areas of cattail marsh and/or Sweet Gale thicket shore wetlands, with the interior dominated exclusively by Sugar Maple-Oak deciduous forest, a community that is rarely found along the eastern shore, where soil accumulation is limited by the Precambrian Shield. The immediate area is known to support Eastern Foxsnake and Five-lined Skink, both of which are Species at Risk in Ontario and Canada. The land donor installed a number of nesting boxes for Wood Ducks which are used frequently.


text:
About Kitasato
About Kitasato University
About The Kitasato Institute
Undergraduate Schools
Kitasato University Hospital
Kitasato University East Hospital
Kitasato University Kitasato Institute Hospital
Kitasato University Medical Center
About the Office of International Affairs
International exchange activities
Shirokane Campus
Sagamihara Campus
Kitamoto Campus
Towada Campus
Niigata Campus
Sanriku Campus Sanriku Education and Research Center for Marine Biosciences(SERC)
Yakumo Experimental Farm
Kitasato Academic Research Organization
Kitasato Memorial Museum
The Center of Education and Research for Agromedicine
Sanriku Education and Research Center for Marine Biosciences
Generating an Excellent Drug from Academia
Our mission is to develop and deliver an excellent therapeutics for the patients through innovative clinical research. Together with four hospitals in The Kitasato Institute, we provide a high quality clinical research for pharmaceutical and medical device industries. Also, we discover an excellent pharmaceuticalseeds and apply them on clinical research. We support global clinical research from academic viewpoints.
A Greater Understanding of the Kitasato Philosophy
To honor the life and achievements of Shibasaburo Kitasato, and to make his philosophy more widely known, starting in 1964, some of his personal articles were exhibited in the research wing of the Institute. These exhibits were moved to the Kitasato main building in 1997 and opened to the public. The number of visitors has now risen to over 60,000. The analysis and examination of the 6,500 items is ongoing, and as new historical facts come to light, they are announced in Donner, our public relations magazine.
Official Site (Japanese Only)
In a speech called "Idouron"(meaning 'a principle for medicine'), Shibasaburo Kitasato said: "The basics of medicine are to prevent illness before it occurred by explaining health management method and importance of physical fitness to the people.", and argued that the basics of medicine are prevention taking the environment into consideration. Great persons in history in several specialized fields such as agriculture, medicine, environmentology and science had similar ideas with Kitasato. For example, "Agriculture nourishes health." –Inazo Nitobe, "All of life will be either healthy or unhealthy according to the fertility (potential) of the soil." –Alexis Carrel. They pointed out the importance of integrated understanding of agriculture and medicine through the environment, and exhort to have an interdisciplinary perspective beyond the specialized fields.
For the inclusive society in the 21st century, integrated thinking from various points of view, which relates each phenomena, is required.
Kitasato University, aspiring to be frontiers of the life sciences, has been advocating "the science of Agromedicine" with its knowledge and technique since 2005. It combines agriculture playing an active role in food production and medicine relating with health promotion through the environment. We firmly believe that developing and spreading "the science of Agromedicine" is essential to solve complicated global problems.
Therefore the University established the Center of Education and Research for Agromedicine to make for a healthy society, and to improve the welfare of humankind through education, research and diffusion based on "the science of Agromedicine".
The Center, based on"the science of Agromedicine" combining agriculture and medicine through the environment, intends to make for a healthy society and to improve the welfare of humankind through cross-cutting education, research and diffusion: prevention of illness, health promotion, development of safe food, implementation of environmental conservation agriculture, implementation of "healing agriculture", environmental reclamation and creation.
Developing and implementing educational programs about Agromedicine
Promoting research on Agromedicine
Publicizing and operationalization of research achievement
Collection, research and analysis of information about Agromedicine
Dispersing information and familiarizing Agromedicine to the public
Copyright © KITASATO UNIVERSITY ALL RIGHTS RESERVED


text:
SD Schools Agree With Transgender Student Sports Policy
SDPB Radio | By Chynna Lockett
SDPB Sports
A recent poll shows about 80 percent of schools in the state support the current guidelines for transgender student athletes. Currently, students who want to participate in a sport as a gender other than that assigned at birth have to get permission through the South Dakota High School Activities Association.
The association sent a survey to all 179 affiliate schools for feedback. The questionnaire asked if the current policy for transgender students needed changing. One representative for each school was asked to answer, mostly superintendents. About 130 gave feedback.
Dan Swartos is the Executive Director for the activities association. He says the policy was implemented in 2013 and has been challenged several times.
"We wanted to see where our membership was at. If they supported it as is or if they wanted to make some changes to it."
He says changes have been made to the policy over the years. Currently, transgender students are required to send information to the association before they're eligible to participate in sports under their preferred gender.
That includes a transcript, a list of accommodations made for the student at the school, a note from a licensed healthcare professional like a doctor or psychiatrist and letters from themselves, their parents and other individuals who know them. Swartos says students are granted a waiver if they're approved.
"It's a waiver to state that this student identifies as a gender other than what's specified on their birth certificate and that they live their life and that they live their lives consistent with that gender. That there's verification that this is not just something that they're doing off the cuff or that they're doing it to gain a competitive advantage."
Swartos say they're able to appeal the decision. So far, less than ten students have applied.
"For us it's way to support those kids and a way to give them opportunities to have the best high school experience possible. And not have to go to school during the day as one gender and then participate as another gender and then participate as another gender in after school activities."
Swartos says the 80 percent approval for the policy might change if other schools send back the surveys.
NewsSDHSAAtransgenderSouth Dakota High School Activities AssociationDan Swartostransgender students


I love it! Will you be glazing it as well? Or leaving it natural?
I will be glazing it partially. I am leaving the bottom half of the lower part unglazed to give a raw/sand like appearance to suggest roots then glazing the rest.
This was sort of an accidental piece. I was setting up to start something else more complicated and my teacher had me show a girl how to make a basic pinch pot (the first thing you learn, ever) because I am good at them. (The vase is two pinch pots) and once I started, I couldn't toss a perfectly good pinch pot.. So I made it into an owl-cup. It's on the small side, so I dunno what I will do with it but it will get glazed as well once it's fired. Our kiln needs a lot more stuff before we can do that.
So far that owl seems to be the crowd favorite. If left entirely to my own devices I think I would focus on more fantasy stuff. Right now I have to make certain kinds of things for class (which is ok, it's great practice).
However my vase came through the initial bisque kiln firing AND DID NOT EXPLODE. HOORAH. (The owl wasn't dry enough yet).
This is what it looks like bisque fired and unglazed. I did glaze it, but didn't get a picture of it glaezed before the next firing.I taped off the outside leaves and dipped it in a light turquoise/green, then once that dried a bit, I removed the tape and painted on a darker green glaze. Some of the other glaze snuck through in the cracks so it might have a neat effect where the glazes meet on the leaves, or it could turn out muddy. We'll have to see. It should be fired by monday, when I have class.
In the interim I am supposed to make a series of dishes with this one technique which I don't like too much, but I am trying to make a soap dish type thing. The clay was pretty wet so it looks a bit warped and it's on the large side. But here it is, partially detailed (first pass) from underneath. Once I am more or less done with the underside, I will flip it and work on the inside.
Your soap dish looks far better than anything I could do. I can't wait to see the picture of the glazed vase.


Albany, NY, Feb 20, 2017: Technavios market research analyst has estimated that the prospect for growth in this market is strongly driven by the wind energy industry, which is influenced by the rising environmental concerns, increased power demand, favorable government support, and the rising need to reduce dependency on fossil fuels. These factors are expected to stimulate the prospects for growth in this market and results in its impressive market value of more than USD 19 billion by 2019.
In this market research report, analysts estimate the APAC region to dominate the global market for wind towers during the forecast period. Market growth in this region is expected to be driven by factors like rapid industrialization, growing power demand, and government initiatives to back renewable power development. These factors promote market growth in this region during the forecast period and results in its high market share of nearly 44% by 2019.
This market is highly competitive and is primarily dominated by large vendors like CS Wind Corp and Enercon Gmbh. Vendors that focus on designing robust and tall towers that can support large capacity turbines in both onshore and offshore conditions are expected to gain maximum prominence in this market.
Other prominent vendors analyzed in this market research are AMBAU, Dongkuk, Gamesa, GE, KGW, Siemens, Suzlon, and Win Wind.
Technavio market research analysts have estimated the tubular steel towers segment to dominate over all the other segments during the forecast period. Growth in this segment is envisaged to be driven by factors like its cost effectiveness and its ability to provide strength to the wind turbine structures, which results in its impressive market share of almost 92% by 2019.
By application, the onshore segment is envisaged to account for more than 92% of the total market share by 2019. Rising onshore wind capacity across the globe is expected to account for this segments high market share during the forecast period.


You can find the final Program here.
Guests staying at the Hostel: You can check in from 2 pm at the Hostel Stintfang (Alfred-Wegener-Weg 5).
All conference guests: Registration starts at 2 pm at the conference center (05) (bus stop Zum Hünengrab/DESY).
The Emerging Science Convention will give you new insights into the evolving field of bioscientific research with a focus on recently developed methods and interdisciplinary approaches. The scientific program will cover the fields of nanoscience, biorobotics, biophysics and more.
Additionally students will have the opportunity to present their own work during the convention.
We are proud to announce Prof. Stefan Hell as our keynote speaker. Prof. Hell won the Nobel Price for Chemistry in 2014 for the development of super-resolved fluorescence microscopy. Additional information about every speaker will follow soon.
Beside the scientific program, we will provide you the opportunity to meet students and colleagues from all over Germany and to discuss your research project in an inspiring environment. Just join us for a Dinner Party on Thursday night.
In my presentation I will introduce the basics of nanopore DNA-sequencing approaches and then focus on discussing our group's most recent effort in this field: nano-channels with embedded plasmonic optics for high-through-put applications. This novel technique based on optical readout already shows promising results detecting nanoscale objects.
Hell, S.W. Microscopy and its focal switch. Nature Methods 6, 24-32 (2009).
In the past 20 years, the world has witnessed the emergence of a number of completely new viruses (e.g., Nipah virus, SARS coronavirus, MERS coronavirus) or of new variants of known viruses (e.g., the H1N1, H5N1, and H7N9 subtypes of influenza virus, Chikungunya virus, Zika virus). All of these emerging and re-emerging viruses use RNA as their genetic material. In our research, we focus on single-stranded RNA viruses of positive polarity, whose RNA is directly translated into a large viral polyprotein that is co- and posttranslationally processed to yield the building blocks of the viral envelope or capsid and the viral enzymes required for RNA replication. This maturation process is performed by one or more viral proteases, which are suitable targets for antiviral drug design. We will discuss our work on the proteases of SARS coronavirus (CoV) (1-3), enterovirus 68 (4), MERS-CoV (3,5,6), and Zika virus (7), and present some highlights of structure-based drug discovery.
(1) Anand, K., et al. & Hilgenfeld, R.: Science 300, 1763 – 1767 (2003).
(2) Verschueren, K., et al. & Hilgenfeld, R.: Chem. Biol. 15, 597 – 606 (2008).
(3) Hilgenfeld, R.: FEBS J. 281, 4085 – 4096 (2014).
(4) Tan, J., et al. & Hilgenfeld, R.: J. Virol. 87, 4339 – 4351 (2013).
(5) Lei, J., et al. & Hilgenfeld: Antiviral Res. 109, 72 – 82 (2014).
(6) Lei, J., & Hilgenfeld, R.: Virol. Sinica 31, 288 – 299 (2016).
(7) Lei, J., et al. & Hilgenfeld, R.: Science 353, 503-505 (2016).
This talk gives an overview on how robotic solutions are developed by taking inspiration from various scientific research areas at the example of the area of deep-sea robotics. What challenges do we have to face when going into deep-sea and why is this sometimes more challenging than going into space? How do sponges, nano fluidic valves and spike trains from neurons influence the design of deep-sea grippers with tactile capabilities?
These and more questions will be answered in this presentation.
Engineered heart tissues (EHTs) are three-dimensional, hydrogel-based muscle constructs that can be generated from isolated heart cells. Like the human heart, these muscles contract rhythmically and develop force. Ever since the technology of human induced pluripotent stem cells (hiPSC) and the differentiation into cardiomyocytes arose, human EHTs are on the verge to replace animal experiments. We have shown in physiological and pharmacological assays that human EHTs replicate findings of ex vivo non-failing human heart tissues and suggest a high versatility of the hiPSC-EHT model as in vitro test system for (i) cardiac drug safety screening, (ii) disease modeling, or for in vivo studies of (iii) cardiac repair.
Cell adhesion is a highly dynamic mechanism capable of adapting to environmental changes and allowing cells to respond by various means. However, the major shortcoming in most biomaterials known today is that they only offer static adhesion conditions, which represents a disadvantage in biological and medical applications. Here we present two successful approaches for dynamic adhesion environments controlled using light stimulation. Both approaches offer a reversible photo-switching of cell adhesion using biofunctionalized azobenzene surfaces. Azobenzenes molecules are able to switch reversibly between two isomeric configurations, namely cis and trans, when exposed to light. We employed this switching concept to develop surfaces that allow a reversible switch between two defined surface conditions by covering glass substrates covalently with c(RGDfK)-functionalized azobenzenes, where c(RGDfK) functions as a ligand to the αvβ3 integrin. The reversibility of photoswitching cell adhesion was demonstrated in consecutive switching cycles by quantitatively characterizing cell detachment forces with atomic force microscopy in situ.
Moreover, we employed surfaces coated with push-pull substituted azobenzenes to exert oscillatory forces on αvβ3 integrins. With this system, we show that the oscillation of c(RGDfK)-ligands leads to increased cell detachment forces and enhances the expression of adhesion-associated proteins such as vinculin, talin, zyxin, and paxillin. Our results provide a stepping stone toward greater exploration of spatially- and temporally-controlled cell adhesion mechanisms, as well as the effects induced by oscillatory forces on adhesion receptors.
Plasmodium falciparum, the causative agent of the severest form of human malaria, kills nearly half a million people annually. The symptoms of malaria are caused by the asexual development of the parasite within red blood cells (RBCs). In this life cycle phase the parasite invades the RBC, transforms it to make it hospitable and then grows and replicates to produce new invasive forms that are released under destruction of the host cell. This intracellular development requires sophisticated adaptions of the parasite and many of the process es occurring during this life cycle phase are specific to this pathogen. In line with this, about 50% of all proteins predicted to be encoded in the parasite's genome show no homology to proteins in other organisms. However, due to technically limitations it has been difficult to study these aspects of P. falciparum biology. This is unfortunate, as it is exactly the processes without precedent in human biology that are the most suitable drug targets. Here I will present recent innovations we use in combination with known gene and protein targeting techniques to study P. falciparum biology. To test this technology, we functionally analysed a list of unknown parasite proteins. In addition the value of this technology was shown by inactivating the Kelch13 protein, which is known to be involved in the resistance of P. falciparum parasites to the currently most important antimalrial drug Artemisinin.
Organs-on-Chip – a revolution in drug testing and personalized medicine?
What are "organs-on-chip" or "body-on-chip", how are they made, and what could they be useful for? My talk aims at answering these questions and provide some insight into this rapidly expanding field of research in the life sciences.
Organs-on-chip are cell cultures mimicking at least to some degree the architecture, cellular composition, perfusion, and biochemical microenvironment found in the smallest functional unit of an organ. They are expected to exhibit in vivo like functions and are envisioned to enable in vivo like answers in preclinical drug testing and could pave the way towards fundamentally novel approaches for personalized therapies.


Personality Psychology Research Papers explore a sample of an order placed for a Psychology class, and explains the format it must be written in, and the subject matter.
Although the long enduring "nature vs. nurture" controversies over whether personality traits are primarily attributable to biological versus environmental factors are unlikely to be decisively resolved at any point in the near future, even the most dedicated advocates of the environmentalist (nurture) perspective now admit that hereditable characteristics may affect how personality develop. Likewise, even the most committed supporters of the biological (nature) emphasis concede that environmental variables play at least some role in mediating the impacts of biological predispositions on personality. Research from the writers at Paper Masters adds further insights into the basis for the emerging consensus concerning the fundamental dimensions of personality traits by maintaining that despite their concrete content disputes most personality theories are based on a common underlying meta-theory, consisting in part of a core statement about mental content that is inborn rather than learned. The author argues that at this level, nearly all personality theories assume that humans are fundamentally the same in terms of the notion that specific inborn characteristics reflect the influences of biological imperatives on mental functioning. Each of the theories also includes a developmental statement that defines how, as a personality tendency is expressed through one's interactions with one's social environment—and through the manner in which influential responds to these expressions—the target person learns how to behave in line with societal expectations.
Harry Stack Sullivan's theory of Interpersonal Psychiatry focused more on the study of interpersonal relationships and how they shape personality and behavior. He was similar to Adler in that he rejected the heavy emphasis on studying the past. Sullivan was similar to Freud in that they both believe that childhood experiences determine adult personalities. Sullivan also believed that social interactions cause anxiety and that individuals develop defense mechanisms to combat uncomfortable situations.
Freud also believed that the mind has three parts: the ego, the id, and the superego. The ego represents a person's everyday thoughts, feelings and behaviors. These are the items that people are aware of. The id represents a person's subconscious thoughts, feelings and behaviors. People are unaware of these and many of these thoughts, feelings and behaviors are deeply repressed. The superego represents a person's ideals and morality. It monitors the interaction between the ego and the id, and according to Freud's theory, any conflicts between the ego and the id cause anxiety and depression.
Freud believed by examining your innermost thoughts and concentrating on the repressed events, an analyst can link them in a way that leads to the patient's understanding. Then, the patient, now aware of them, can process them and incorporate them into his/her conscious understanding. This allows the person to move beyond the repressed items.
Carl Jung was probably the most like Freud in his theories about personality and behavior development. His Analytical Psychology included three parts (similar to Freud's): the ego, personal unconscious and collective unconscious. The ego is the conscious mind; the personal unconscious includes items that a person can consciously remember (e.g., memories) as well as ideas and feelings repressed into one's subconscious; and the collective unconscious consists of a "psychic inheritance" that individuals are born with that represents the collective experience of all species. Jung also developed the idea of archetypes. Archetypes make up the collective unconscious and categorize our actions. Each archetype helps us understand what we expect of that type of person.
Recent developments in the research on personality traits are indicative of an emerging concerning the fundamental dimensions of personality traits involves the growing acceptance by specialists in different braches of psychology that personality traits develop as a result of the complex (and as yet poorly understood) interactions between a combination of variables. Although supporters of contending schools variously argue that personality traits develop primarily due to genetic, environmental, or brain-related influences, the authors' analyses suggest that none of these models fully captures the complex pictures of how personalities develop. For instance, the authors note that not even monozygotic twins—individuals whose genetic makeup are identical—develop highly similar personalities: a necessary observation if one is to support the notion that personality is primarily genetic. Likewise, the authors indicate that despite strong support for the notion that environmental factors have profound impacts upon personality development, the fact that even siblings raised in shared household environments develop entirely different personalities indicates that environment cannot explain everything.
Such mounting evidence appears to be driving scholars and practitioners from various theoretical schools towards at least some agreement that personality traits develop through the interactions of multifaceted variables. In line with such findings, for instance, the majority of leading scholars now concur that addictive personality traits are the product of several diverse biological, environmental, and psychological influences. This growing concurrence derives in large part from a sizeable and steadily increasing body of literature indicating, for example, that both environmental and genetic are involved in the widely observed tendency for alcoholic personality traits to be evident in specific families across generations. Whereas genetic factors appear to account for between 40 and 60 percent of this heritability, environmental factors such as life in households where alcohol is used as a "coping" mechanism are believed to account for much of the remaining proclivity for alcoholic personality traits to transcend generations in the same families.
A similar consensus may also be evolving, though at a somewhat slower pace, around the likelihood that criminal personality types are shaped by interactions between a number of contributing factors. Some specialists continue to insist that violent criminal personalities are linked to brain disorders precipitated by tumors, head injuries, neuropsychological dysfunctions in the left hemisphere, and/or low cortical arousal. By contrast, supporters of a competing view argue that the major biological factors implicated in the development various types of violent, criminal personalities are genetic rather than brain-related. Yet other experts have for decades heatedly contested the very idea that violent criminal personalities may be linked primarily to either brain-related or genetic variables, forcefully maintaining instead that violent personalities are almost entirely the result of environmental influences. According to these theorists, violent criminal personalities develop mainly—or even exclusively—as an outcome of the negative cumulative effects of acute abuse in early childhood, neglectful and/or violent school and community environments, and grossly inadequate social services.
Although the supporters of these contending models are as yet hardly ready to abandon their disputes, growing numbers of researchers agree that although biological factors play important roles in predisposing certain individuals to criminal violence, these predispositions require critical environmental triggers for actively criminal and violent personalities to develop. Such integrated models prove more satisfying for those concerned about the limitations of strictly environmental models for explaining why the overwhelming majority of people reared in even extremely adverse home environments never develop violent criminal personalities. The integrated models are also appealing for those who challenge the notion that everyone with a biological predisposition to criminal violence will, regardless of environmental circumstances, develop such a personality.
A clear description of the theories of personality, with biographical information that places any specific personality theory in socio-cultural-historical context. A clear description of what is unknown or fictionalized for the point of illustration.
Clear introduction to the theories that you are using as a basis for your project.
Complete and concise description of the organizational approach to describing the personality trait in relation to the theories. How should the reader approach your discussion?
Clear use of scholarly literature that includes current research, theory, and practice or a description of omissions in the literature. This should not be comprehensive, but does reflect the "state of the art" or most important contributions in the area.
Citation procedures following APA guidelines are correct.
Birth Order and Personality - Birth Order and Personality research papers custom written for college and university students.
A Primer of Freudian Psychology - A Primer of Freudian Psychology defines personality as having three major parts; the id, the ego, and the superego.
Freud Latency Stage - Freud Latency Stage research papers look into the fourth stage of Sigmund Freud's 5-stage framework of childhood and adolescent psychosexual development.
Freud - Freud research papers discuss Freud and his psychological theories.
Social Development in Children - Perhaps even more importantly, Erikson was the first major theorist to suggest an "epigenetic sequence of personality development over the lifespan".
Paper Masters writes custom research papers on Personality Psychology and explore a sample of an order placed for a Psychology class, and explains the format it must be written in, and the subject matter.


text:
Note from Minneapolis
I've been in Minneapolis since yesterday afternoon for the ELCA Churchwide Assembly (CWA). You can follow the action at this link.
An official ELCA news release having to do with the sexuality business that I've been writing about in this blog says that the CWA:
"...turned back a motion that would have required a two-thirds majority for changes in policies relating to the rostering of clergy, associates in ministry, diaconal ministers and deaconesses. The vote, with 57 percent in opposition, came late in the evening of the first day of the gathering.
"A vote to allow people living in committed same-gender relationships to be on the professional rosters of the ELCA is scheduled for Friday, Aug. 21.
"The action leaves in place a recommendation that a simple majority vote be sufficient for the proposed policy changes."
After last night's session ended, I went to a meeting of Lutheran CORE, one of the unofficial groups that is getting together during the CWA. Lutheran Core believes church decisions should be based on scripture.
I am a supporter of Lutheran Core. I am concerned that the ELCA makes some decisions in a way that dishonors what God has revealed in the Bible. No church has perfect knowledge of God's will, but in some matters, including sexuality, I believe that the ELCA has drifted away from its scriptural basis.
I encourage you to look at the news releases produced by Lutheran Core. This morning's Lutheran Core news release said this:
The ELCA Churchwide Assembly voted 584-436 Monday night to reject a proposal that would have required a two-thirds majority to change ELCA teaching and policy to allow pastors to be in same-sex relationships.
The assembly rejected appeals from voting members including five synod bishops that a two-thirds majority would serve the unity of the ELCA.
"A two-thirds vote would indicate how seriously and carefully we have addressed this topic," the Rev. Larry Wohlrabe, bishop of the Northwestern Minnesota Synod, told the assembly.
"Right now this church requires of us a higher standard," said the Rev. Callon Holloway, bishop of the Southern Ohio Synod.
Leaders of Lutheran CORE expressed disappointment in Monday's decision. "I am very disappointed that the voting members seem willing to let basic Christian teaching be overthrown by a simple majority vote of a tiny percentage of ELCA members," said the Rev. Steve Shipman of Lock Haven, Pa. "Such a decision would lack any legitimacy both ecumenically and among our members."
"The assembly seemed intent on achieving a particular legislative objective rather than considering the wider implications of the action on the ELCA and on the global Christian community," said Ryan Schwarz of Washington, D.C.
"It is a shame that the assembly intends to make such a serious decision by a majority margin. It shows utter disregard for most of the rest of the Christian Church," said the Rev. Mark Chavez, director of Lutheran CORE.
"Consideration of these proposals threatens the ELCA's relationship with our partner churches in the Lutheran World Federation. Church leaders from Africa, Asia and Eastern Europe have already written letters stating that approval of the sexuality proposals would greatly damage the ELCA's relationship with their churches," said the Rev. Mark C. Chavez, director of Lutheran CORE. "These proposals will also severely damage the ELCA's relationship with Roman Catholics, Orthodox, and most Protestant Christians."
"The ELCA has already been damaged significantly just by presenting the sexuality proposals to the Churchwide Assembly. And the damage will be compounded no matter what the assembly decides," Chavez said. "A Christian church has no business voting on whether the Bible is relevant to the faith and life of its members."
Respected theologians and church leaders say the proposed social statement would overturn Biblical teaching as it has been understood by Christians for nearly 2,000 years.
"No church has the authority to overturn the Word of God that protects sexual relations by placing them properly in the structure of marriage, and establishes marriage as being between male and female," said the Rev. Erma Wolf of Brandon, S.D., vice chair of the Lutheran CORE Steering Committee. "When any church finds itself accommodating its teachings to the ways of the culture, that church is in trouble."
A group representing another view is Goodsoil.
"Goodsoil is a collaboration of organizations working for the full inclusion of lesbian, gay, bisexual and transgender people and their families in the full ministerial and sacramental life of the Evangelical Lutheran Church in America (ELCA). [Goodsoil works] to reconcile our church's policies and practices regarding same-gender marriage, blessings of covenanted unions, and the rostering of partnered LGBT ministers, harmonizing these with our shared values of faith, trust, commitment, monogamy, mutuality, and dignity."
I think Goodsoil, and many within the ELCA, would strongly disagree with the thesis I posted on Saturday. I am putting it up on this blog again today in the hopes that people from our church or others would comment below.
Because God has chosen to create, protect and nurture human life through the sexual act and committed love of one man and one woman, therefore we honor committed heterosexual monogamous marriage above all other forms of sexual intimacy.
Please continue to share your opinions on that thesis and any of the other issues that will impact our church's future.
Steve --
I'm a gay Christian man in Minneapolis who is closely following the news coming out of the ELCA. The decision Friday will determine whether I feel new hope or old condemnation upon walking into an ELCA church. No matter the systematic theology of a vote against gay pastors and same-sex relationships, it would feel like a vote that I'm not wanted there.
Steve Thorson August 18, 2009 at 12:13 PM
Yeah, I get it. That's why this is hard.
Thanks for getting it... that's more than I'm used to. I'm praying for you all.
Wayne August 18, 2009 at 3:46 PM
Pastor Steve. The Word of God is CLEAR. Trust his word and stay true to faith. No one ever said it would be easy..Love and Prayers
Steve Thorson August 18, 2009 at 4:11 PM
There is no question, Wayne, where I stand personally. The ELCA pastors in the Dassel-Cokato area are in agreement too, which makes things easier locally. The question has to do with how we, with you and all those who are affiliated with our churches, will respond to ELCA actions with which we believe are unfaithful to God's creative order and His revealed truth.
Tim August 18, 2009 at 4:24 PM
Pastor Steve:
This is hard. No matter which side of this issue one comes down on, the other side can point and say, "Hypocrite!"
This issue touches me personally because my brother is gay. So I'm not coming from a totally bigoted, homophobic angle. I love my brother. He's the only one I have. I don't understand why he has the feelings he has. Did God make him like this? If so, is this his cross to bear? (Steve, I'd like to speak more with you about this at a later time.)
But I believe the Bible clearly lays out that sexual relations outside of marriage between a man and a woman is sin. Given that, I don't know how the ELCA as a whole can pass any kind of resolution which would, in effect, condone same-sex marriage.
Are we to operate as if sin doesn't matter? Our sins are forgiven so we don't need to repent, just do what feels good? That's how the world operates. But with the Spirit living in us we are not of the world.
Tim R
Thanks, Tim, for being so open in sharing our common struggle with all of this. Take time to read some of the back and forth in comments that have been submitted this month. Those who can't can't be at the assembly can hear the back and forth debates on the assembly floor, but only in real time as far as I know at www.elca.org -- I would hope there would be a way of listening later or reading transcripts. There are many heartfelt comments on both sides. The question for me is whether we are going to let our emotions guide us or whether there is something and someone higher than our feelings (God in creation and scripture) that we need to hear. God is greater than our hearts. He does not condemn us, but only because Jesus was sacrificed in our place.
Good morning Pastor Steve. I looked back at your August 17 post and in that you wrote "One thing I wish for is comments from you!". It looks like your wish came true! Have a great day down there. We prayed for you last night at Bible study for guidance and clarity. You have our support brother..
Mike L
Steve Thorson August 19, 2009 at 10:06 AM
Thank you, Mike. Please be in prayer specifically for Steve Olson, Mike Nelson and Mark Little too, as they are pastors of ELCA churches in the DC area.
DR Bloomquist August 20, 2009 at 8:28 PM
Thanks for our frank and mutually-enlightening dialogue you and I had in Room 204AB at the Minneapolis Convention Center, Pastor Steve.
I believe that the LORD Jesus Christ has a leadership destiny for you not merely in strongly influencing the present ELCA leadership and voting members with respect to what the totality of our Sacred-66-books Scripture has to say against both homosexuals and homosexuality.
DR - I have never felt a call to speak against homosexuals.
DR - could you please identify yourself more fully so we can dialog more?
DR - please look at my post from Thursday, August 28, 2008 - here's the link, but I don't know if links work in comments... http://equalsharing.blogspot.com/2008/08/log-in-my-eye.html
Pulpit Supply Sep 6
Meeting Today
Sticking with Jesus (audio)
Unbinding the Conscience
Crabby Christians?
Sticking with Jesus
Friends for the Journey
Next - Impementing Resolutions
Appreciation & Concern
What Would You Wish For?
Wisdom & Love
ELCA Sexuality Business
The Challenging Truth
Crossing the Street
Home Tuesday


The topcoat has been shielding wearers from the elements for centuries and, as evidence of its timelessness, the design has remained relatively unchanged. It is a piece mostly worn over uniforms and suits, and it traditionally exudes professionalism. Today, the topcoat has been tweaked ever so slightly to be in line with modern tastes (shorter in length and with a slimmer silhouette), and men have started wearing the coat in innovative ways. In contemporary fashion, the topcoat can be seen worn over any imaginable outfit — from an Italian three-piece suit to a tailored crew-neck sweatshirt and faded jeans. What this means is that the topcoat has become an essential piece of outerwear fit for most any occasion, beating both the elements and trends at the same time.


It's new! There was a previous version a few years back, but Vizam the Nikto brings us another update from the 6-joint era! It's nice, it has a helmet, and it has another cool clamp-on cannon for the Sail Barge Hasbro will never make. Aren't you lucky? Read on! Because you are, you really are lucky.


text:
Q: Dynamics 365 CRM integration I am working on an integration code to connect the On-Premise CRM to online. We updated the CRM from Dynamics 2015 to 365 and we need to update the on-premise CRM as well. The integration program needs to update the dlls referenced in order to integrate with Dynamics 365. When I try to connect using the credentials, an error is thrown as follows
"Exception thrown: 'System.NotSupportedException' in Microsoft.Xrm.Sdk.dll"
I cannot downgrade the dll version on this as it is of no use. This is the code I used to connect.
    using Microsoft.Crm.Sdk.Messages;
    using Microsoft.Xrm.Client;
    using Microsoft.Xrm;
    using System;
    using System.Collections.Generic;
    using System.Configuration;
    using System.Linq;
    using System.Net;
    using System.Net.Security;
    using System.Text;
    using System.Threading.Tasks;
    using Microsoft.Xrm.Tooling.Connector;

    namespace Integrations
    {
        class Program
        {
            static void Main(string[] args)
            {
                Console.WriteLine("Starting connection...");
                ServicePointManager.SecurityProtocol = (SecurityProtocolType)3072;
                string connectionString = ConfigurationManager.ConnectionStrings["CrmConnection"].ConnectionString;
                Console.WriteLine(connectionString);
                CrmServiceClient conn = new Microsoft.Xrm.Tooling.Connector.CrmServiceClient(connectionString);
                if (conn.IsReady)
                {
                    Console.WriteLine("Starting integrations...");
                       IntegrationMethod();
                    Console.WriteLine("Completed integrations... Closing.");
                }
                Environment.Exit(0);
            }
        }
    }

Any suggestions would be helpful.

A: It's probable that the Microsoft.Xrm.Sdk version it's superior to the SDK version in your Dynamics 365, example if you have v8.2 you cant use Microsoft.Xrm.Sdk version v9.0 (or superior) to connect, Sdk version from 7.x to 8.2 are forward-compatible only not backwardcompatible (MSFT link)
Have in mind that SDK version 9 deprecates support for previous version
Hope it helps
Regards

redpajama_set_name: RedPajamaStackExchange