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Book Review: The Lemon Grove
The Lemon Grove by Helen Walsh
The blurb: Sun. Desire. Obsession. An explosive, intelligent novel from the prize-winning author of Brass.
One hot summer. One week in a villa on the outskirts of Deia, a village nestling in the rugged, mountainous west coast of the island of Mallorca. One family for whom the carefully laid jigsaw of life is about to be broken.
Jenn and her husband Greg holiday each year in Deia, enjoying languorous afternoons by the pool. But this year the equilibrium is upset by the arrival of Emma, Jenn's stepdaughter, and her boyfriend Nathan. Beautiful and reckless, Nathan stirs something unexpected in Jenn. As she is increasingly seduced by the notion of Nathan's youth and the promise of passion, the line between desire and obsession begins to blur. What follows is a highly-charged liaison that put lives and relationships in jeopardy, and a taut narrative which percolates with enough sexual tension to make it impossible to put down.
My review: I'm split with this book. On the one hand I loved the evocative beautiful locations, I was literally transported to previous summer holidays in secluded villas where you're wrapped up in a bubble of otherwordly-ness, the sense that it belongs to you, a feeling that you would fight to sustain. The heat and the seclusion being the perfect time to reflect on the troubles in your life. Such a perfect set up for a novel.
But then on the other hand this book just didn't deliver for me. It seemed it had so much potential, so much great material set up for emotional explosions and then it all just went south and became all about the sex. Jenn's relationship issues with her step-daughter could've been so emotive and interesting, her guilt at her affair seemed poorly drawn (maybe she just wasn't guilty!) and her inner-turmoil a brief flash before being swept away, the sexual tension barely there and her previous pre-marriage life had so much mileage for exploration.
But I felt all these harrowing, emotive topics that fit with the seclusion and protective possession of the landscape became merely side-notes as soon as sex was on the table (and everywhere else.) I am by no means prudish when I come to my reading but do beware if you're not a fan of graphic descriptions. All the inner turmoil seemed to be shrugged off in favour of juicier sex scenes which have their place if there's the story in place to support them which I personally just didn't think had been developed enough. The cover I think tells a different tale to the one between the pages.
But this is a beautifully written book, and there have been many great reviews about it already, perhaps it's just not one for me.
February 21, 2014 by wordsandpieces	Headline


These handmade IKAT cushions are the perfect addition to your home. They come in a variety of stunning designs and colours, plus there are various sizes. You can mix and match or find a style that you love. They are made in a traditional IKAT way (Read my blog about how IKATs are made)with silk and cotton blend. This offers the perfect mix of luxurious looks and practicality - plus they are lovely to the touch. Please note that the price is for the cushion cover only. Need a cushion pad? Check out our Duck Feather Cushion Pads 40 x 40 cm.


Here's something to go with the presidential inauguration: According to Foodimentary, today has been declared National Cheese Lover's Day.
It's an easy holiday to love, granting permission to American cheese beasts to indulge in one or more of their favorite cheeses. Perhaps your cravings are satisfied by the processed cellophane-wrapped singles of your youth. Or maybe you've graduated to runny and pungent washed rind cheeses such as Italy's Taleggio or Red Hawk from California's Cowgirl Creamery.
But I'd like to single out a cheese that doesn't get a lot of attention in the U.S., a cheese made since Byzantine times on Cyprus in the Mediterranean sea: Halloumi, pronounced "ha loom' ee". So revered is Halloumi in this island culture that per capita consumption per year is nearly 18 pounds. For me, the main attraction is that the cheese has a high melting point, meaning it can be grilled without collapsing through the bars of the grill grate. You can even fry it on a plancha.
Primarily made of sheep's milk and goat's milk (post-20th century versions of Halloumi often include cow's milk as well), this salty white cheese has a toothsome, almost squeaky texture. The outside caramelizes to an appetizing golden-brown where it makes contact with the heat—notice the grill marks in the photo above—while the inside softens somewhat. It is usually sold in vacuum-packaged slabs in a small amount of brine. Halloumi's versatility has endeared it not only to Cypriots, who enjoy it for breakfast with smoked pork loin called lounza, but to Middle Eastern countries and improbably, Great Britain.
Slice the cheese (about 12 ounces) into 3/4-inch slabs. Brush on both sides with a good-quality olive oil. Preheat the grill to medium-high and grill the cheese for 2 to 3 minutes per side, turning 90 degrees after the first minute or two for a handsome crosshatch of grill marks. For serving, shingle the cheese on a platter, drizzle with additional olive oil, and sprinkle with coarse salt. Serves 4 as an appetizer or meze.
Grill the cheese as described above, but drizzle with honey and omit the salt. Serve with grilled bread.
The Parthenon restaurant in Chicago's Greektown debuted this dish in 1968: Grill the cheese as described above and arrange on a heatproof platter. Preferably wearing extra-long grilling gloves, pour a small amount (about 1/2 cup) of slightly warmed ouzo or metaxa (Greek brandy) over the cheese and carefully flame with a long-stemmed match. Douse with a squirt of fresh lemon juice. Serve immediately.
Make a marinade: Combine the juice of 1 lemon with 1/2 teaspoon salt, 1/4 teaspoon red hot pepper flakes, 1 tablespoon chopped fresh dill or other herbs, and 6 tablespoons of olive oil. Arrange the slabs of Halloumi in a single layer in a nonreactive baking dish. Pour the marinade over the cheese, gently turning to coat it on all sides with the marinade. Let marinate for 1 to 2 hours. Grill as described above.
Double the marinade recipe above. Cut the cheese into 1-inch cubes along with onions, bell peppers, zucchini or yellow squash, or mushrooms. (Make sure the cheese cubes and vegetables are the same size.) Marinate the cheese and vegetables for 2 hours. Thread the Halloumi and vegetables on skewers (bamboo or metal skewers). Grill for 1 to 2 minutes per side, or until the cheese is lightly browned and the vegetables are tender-crisp.
Grill Halloumi as directed above and serve with cubes or slices of melon. In Cyprus, the combination of cool watermelon and Halloumi is classic, but use whatever melon is in season.
Substitute cubes of grilled Halloumi for smoked mozzarella in my take on Caprese Salad.
Read about other cheeses that can be grilled.


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Q: Check receipt if there is five or more of a product I have a basic object SalesLine, which contains the property quantity. I need to know if any of the SalesLine object has a quantity of five or more. In a simple world, you could just check if the SalesLine object has 5 or more of quantity:
foreach(SalesLine salesline in Transaction.SalesLines
   {
     if(salesline.Quantity >=5)
   }

but unfortunately we do not live in one. If a cashier scans 4 of product a, then scans product b, then scans one more of product a, it won't be summarized on one line. We now have three salesline in Transaction.SalesLines, but only two unique products. To know which SalesLine are of the same product, we can use the property SalesLine.ItemID.
How would one write a code which basically checks if there exists five or more of any of the unique products?

A:
If a cashier scans 4 of product a, then scans product b, then scans one more of product a, it won't be summarized on one line

Then fix that when scanning an item and adding it to your collection? It makes the entire process easier, including printing a receipt.
Alternatively, group all lines by a unique identifier for the product, so something like:
foreach (var products in Transaction.SalesLines.GroupBy(s => s.EAN))
{
    int productQuantity = products.Sum(p => p.Quantity);
}

A: You can try this. This will summarize quantity by itemid
foreach (var item in list.GroupBy(x => x.ItemID).Where(x => x.Sum(i=>i.Quantity) >= 5))
{
    /*your stuff*/
}

redpajama_set_name: RedPajamaStackExchange


Is United Check Recovery Bureau, Inc. harassing you with constant phone calls? Do they threaten to take legal action or garnish your wages? Are they calling you at all hours or several times a day? Are they telling your family and neighbors that you owe a debt? If so what they are doing is illegal and needs to stop. You have the legal right to stop United Check Recovery Bureau, Inc. phone harassment.
Who is United Check Recovery Bureau, Inc.?
United Check Recovery Bureau, Inc. is a third-party debt collector that is currently based out of West Seneca, NY 14224.
United Check Recovery Bureau, Inc. currently has a B+ Rating the "Better Business Bureau" with over 12 filed complaints!
Are you receiving harassing Phone Calls from 1-800-771-5361?


BOYS who led prayers throughout Ramadan have been praised by a mosque leader .
Fraz Ahmad, Takreem Ahmad, Sarmad Anwar and Hud Anwar have been taking the lead at the Al Mahdi Mosque during the Holy Month, which started on June 17 and ended today.Mohammed Iqbal, the president of the Ahmadiyya Muslim Association Bradford North, which meets at the mosque in Reece Way, Bradford, said Ramadan was a time when Muslims were expected to concentrate on their personal spiritual development.
"During this Ramadan the Muslim community of Bradford has not only had to face the year-on-year turmoil in the Muslim world, they have also been under the political and media spotlight after a misguided family of 12 travelled from Bradford to Syria, apparently to join ISIS," he said.Dr Iqbal said one of the issues raised by independent commentators was that people attracted to extremist ideologies wanted to safeguard their Muslim identity and felt they were not welcome in Britain, which he said was nonsense in Bradford."The young Ahmadi children, like all our members are proud British citizens and proud Muslims.
Share the post "Prayer boys praised for Ramadan efforts"


1. An exciting future ahead!
During the past year, Rullion has been featured in industry press sharing details of our expansion and areas of focus. It's no secret that we aim to become market leaders in both niche recruitment and outsourcing solutions and now have platforms in place for making our goals a reality. It's our vision to become the most admired recruitment company in the UK. Watch this space!
Our nationwide offices are described by employees as having a friendly and supportive atmosphere and come with plenty of perks. With beer Friday (free drinks at 4pm), complimentary fruit deliveries throughout the week and cool break out areas, it's no surprise that many of our employees have worked here for more than ten years. Even our directors and CEO work alongside colleagues, are seen day-to-day and always have time for a chat.
We're committed to bettering our people...continuously. We've our dedicated Sales Academy; a series of courses designed to equip recruiters with tools and skills throughout every level of their career, 'Good to Great' and leadership training and exclusively developed programmes for specialist business areas, such as Niche.
We never stand still, and we're well known for it! Not only do we invest in the development of our people, we constantly work to improve our processes, our technology and our customer service. Like the sound of being part of an ever-evolving business? Get in touch!
With 40 years' recruitment experience under our belts we've an established brand and a reputation for providing leading recruitment services to some of the UK's best known businesses. Join us and our impressive client portfolio could become yours too.
We have competitive commission structures in place for recruiters, and benefits such as pension and buy-more-holidays schemes for all employees. We're able to offer flexible working options too, ensuring a great work-life balance for all.
There's always a night out in the calendar...from lunch in a local pub, to after-work drinks in a bar; from individual team bonding activities and performance-linked rewards, to a company-wide ball. If you see yourself as a bit of a socialite, Rullion should be at the top of your list of potential employers.
We describe ourselves as forward thinking and we like to think outside of the box. From a CEO who comes from a finance background (rather than recruitment), to our exclusive and unique events, we never follow suit.
And a career can be very rewarding. Recruitment, particularly in Rullion, offers a wide range of progression opportunities where top performers can fast track their careers. The work is varied and challenging, but for driven, entrepreneurial individuals it can bring immense job satisfaction.
If you're interested in playing your part in the next chapter of Rullion's exciting journey, have a look at our vacancies! We'd love to hear from you.


Sandra Handy is a freelance web content writer with a passion for helping businesses and clients optimize their online presence to drive leads, conversions, and awareness.
If you always imagine about making a diverse career but lack the courage to act on that dream, it may turn out you're operating under the supposition of a job myth. What is a job myth? How do you scale through and overcome the myth? Well, keep reading as this article is set to expose ten myths or sayings you might have heard before that are just not genuine.
Yоu frееlаnсе wrіtеrѕ hаvе to bе wоndеrіng nоw, rіght? With that glоrіоuѕ introduction, I'm going tо fіll уоu іn on thе cross-my-heart-hope-to-die-stick-a-needle-in-my-eye freelance wrіtіng ѕесrеt. It'ѕ Guru.com. And bеfоrе уоu run screaming to the 'dеlеtе' buttоn, let me ѕау uр frоnt thаt I'm іn no wау, ѕhаре, оr form оn Guru's payroll! I'm not an affiliate (they dоn't hаvе аn affiliate рrоgrаm). I dоn't оwn stock (іn fact, I thіnk іt'ѕ рrіvаtеlу-hеld?).
Dіd уоu know thаt уоu саn burn a lot оf саlоrіеѕ dоіng house chores? Aссоrdіng tо fіtnеѕѕ еxреrtѕ, hоuѕе chores саn burn up to аn average of 250 calories in аn hоur for a 150-lb іndіvіduаl. This роѕt has hіghlіghtеd ѕоmе оf thе ways уоu can uѕе уоur house сhоrеѕ tо buіld up a sweat аnd get fit while dоіng hоuѕеwоrk.
A massive transformation is going on underground in the legal industry, no doubt about it. Attorneys in all fields are learning to be flexible to attain today's digital marketplace. Young lawyers and even law students must start learning their chances of survival, understand the new-look of the legal industry, and study the market shift.


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Island Health acknowledges design issues, long-term care plans for new hospitals
James Wood, contributor, Tuesday, Feb. 6th, 2018
COMOX, B.C- Island Health has acknowledged a series of issues with the new hospitals in the Comox Valley and Campbell River.
A series of reports from Decafnation, a blog run out of the Comox Valley, described multiple problems currently affecting the new facilities, running from planning and design issues to low employee morale.
Back in January, Jeff Beselt, the Executive Medical Director of Island Health, spoke to 98.9 The Goat about the reports and issues at the hospital.
While he did state that not everything in the Decafnation report was accurate, he acknowledged many of the issues being reported were happening in both hospital campuses. He also said that planners "did not get everything right", while defending the actions taken by the health authority.
Now, a new statement from Island Health is appearing to echo Beselt. The document was posted to the Island Health website on Friday, and starts off by describing the numerous improvements to local healthcare that came with the new facilities.
"Planning, construction and the opening of the North Island Hospital campuses was a huge undertaking," read the statement.
"This included changes in technology, equipment, clinical practices and policies, physical locations and staff and user learnings – changes unprecedented in scope at Island Health."
Island Health also mentioned recent "public statements" touching on the Comox Valley hospital, without describing them in detail.
"While we know there are inaccuracies in some of these statements, we also acknowledge there are truths," read the statement.
"This is a normal part of a change of this magnitude and we want to assure our staff, physician partners, patients, volunteers and the communities that the hospital serves, that we are listening and working very hard to make necessary improvements."
The statement goes on to say that Island Health is working to "identify and improve deficiencies", and "streamline building systems".
"This is an ongoing process, expected with the opening of any new hospital," read the statement.
"Island Health staff and physician partners had similar experiences leading up to and after the opening of the Patient Care Centre in Victoria in 2011."
It also touches on the design process, mentioning the involvement of more than 35 user groups and more than 300 people.
"This was not a simple process, or one taken lightly," read the statement.
"We know that while the North Island Hospital has improved care and care delivery in many ways compared to our previous hospitals, we did not get everything right. We are continually working with our teams to learn and improve. With a project budget of more than $600 million, hospital design involved many tough decisions, balancing health care demands with responsible use of taxpayer dollars. Many initial decisions were made to advance work and planning, followed by the opportunity after move-in to the hospital campuses to re-evaluate those decisions and course correct as required."
The statement finishes off by describing the current capacities of the Campbell River and Comox Valley hospital campuses, which combine to hold 248 inpatient beds. A total of 95 are currently in use in Campbell River, while 129 are being used at the Comox Valley hospital, while 24 were "intentionally built" for future use.
"Like all other Island Health acute care facilities and hospitals across the province, in recent weeks both North Island Hospital campuses have been experiencing increased patient volumes due to seasonal illnesses," read the statement.
"This, coupled with patients awaiting placement in long term care facilities, does create staffing and bed challenges. To mitigate these seasonal surges in patient volumes, temporary overflow patient care areas are opened and all patients are cared for in appropriate care spaces and with increased staffing levels. While Island Health acknowledges that this is not always ideal for patients and staff, patients can be assured they will continue to receive the safe, quality care they have come to expect from their health-care professionals."
A focus was placed on the Comox Valley campus, which was said to be experiencing high patient volumes in recent weeks due to seasonal illnesses. The average occupancy from October of 2017 to the end of January 2018 was 110 per cent, based on 129 beds.
A need for more long-term care capacity was also acknowledged.
"Work is underway to issue a Request for Proposals and we anticipate this will move forward within the next few weeks," read the statement.
"This new capacity will help meet the needs of the community. Island Health also recognizes that it will take approximately two years to open this new capacity once the RFP process and design is completed. In the interim, Island Health is adding resources in the community to better support people to live in their own homes longer – last year home care visits totaled 38,306 and we are projecting an increase of more than 1,800 home care visits this year."
98.9 The Goat has reached out to Island Health for more comment on this matter.
Editor's Note: A response from Island Health regarding inaccuracies in the Decafnation reports included the following main points.
The initial Decafnation article stated that "The P3 arrangement means that VIHA provides the operating funds for the hospital. The building itself is leased from Tandem Health, the private partner."
This statement is inaccurate. The building itself is owned by the Province of BC, and is operated by Island Health. This inaccuracy is also repeated in Article #3.
The first article also states that the cost of the North Island Hospital, Comox Valley was $350 million.
The cost was $331.7 million. This inaccuracy is also repeated in Article #2.
The first article also states that St. Joseph's General Hospital was over capacity on the day it closed.
Patient numbers were reduced for purposes of the move to NIHCV. SJGH had 94 acute patients on move day and the SJGH bed capacity was 122.

redpajama_set_name: RedPajamaCommonCrawl


A report out today from iSuppli claims that global notebook sales surpassed desktop PC sales for the first time last quarter. But I feel like I keep seeing that headline over and over so I'm not going to put too much stock in it. Much more interesting is iSuppli's finding that Acer's market share was up 45 percent from the previous quarter, and 79 percent from the same quarter last year. What accounts for the jump in Acer's standing? Netbooks.
Acer is now the number three computer maker in terms of the quantity of PCs shipped. Hewlett Packard holds the top spot, followed by Dell. But Acer comes in a strong third thanks to the fact that the company shipped 3 million more notebooks in the third quarter of 2008 than it had in the second quarter. And most of those 3 million additional laptops were netbooks in the Acer Aspire One line.
While Asus has also been selling a lot of netbooks this year, the company doesn't sell nearly as many full sized computers as Acer, and doesn't come near the top 5. Lenovo and TPC makers (in terms of quantity, not necessarily quality), offer at least one netbook model. But then, pretty much every major computer maker except for Apple and Sony offer some sort of cheap mini-laptop. So maybe that's not such a big deal.
Apple, by the way, now comes in third in the US in terms of market share. But the company holds a much smaller piece of the global pie.
If I had not bought my Samsung the Acer Aspire One was on teh top of my list. If I were to buy a Linux machine I'd get that one.


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upGrad Business (Revenue) Model | Success Story of upGrad (Business Model of upGrad)
December 11, 2021 December 11, 2021 Shubham 0 Comments Revenue Model, Revenue Models, Startup, Startup News, Success Story, Unicorn Club, upGrad
UpGrad business model works on a two-way approach that bridge the gap between the learners and learning providers to make them future ready, started in 2015. It is an EdTech startup that came out with the motive to help students with their higher education.
It is a business where they provide multiple courses to the students which students can easily access from anywhere. They also caters a large variety of courses ranging from undergraduate programs to Master's degree programs.
Master's degrees and some post-graduate programs are only offered on a fee payment system. Otherwise, most courses are at very nominal cost or free of cost. All the courses offered a completion certificate unlike other educational applications in the market.
upGrad Brand Ambassador – "Vicky Kaushal"
By the End of this article, you'll know:
upGrad Company Highlights
upGrad – Name, Logo and Tagline
upGrad Vision and Mission
About upGrad
Founder of upGrad
upGrad Business Model
upGrad Revenue Model
Revenue Model of upGrad
upGrad Competitors
CoinDCX Company Highlights
upGrad Vision and Mision
upGrad – Founders and Team
1. Ronnie Screwvala | Co-founder & Chairman, upGrad
2. Mayank Kumar | Co-founder & MD, upGrad
3. Ravijot Chugh | Co-founder, upGrad
4. Phalgun Kompalli | Co-founder, upGrad
upGrad Business Model | upGrad Revenue Model
Articles Related to upGrad Business Model (Revenue)
upGrad – Competitors
upGrad – Acquisitions
upGrad Aquisitions
Headquarters Mumbai, Maharashtra, India
Industry Edtech
Founders Ronnie Screwvala
Mayank Kumar
Phalgun Kompalli
Ravijot Chugh
Parent Organization UpGrad Education Pvt. Ltd
Employees 3350+
Net Worth $1.2 Bn Valuation (August 2021)
Website www.upgrad.com
NAME of the STARTUP – "upGrad"
TAGLINE – "Building The Careers Of Tomorrow"
upGrad is an EdTech startup that came out with the motive to help students with their higher education.
UpGrad Logo
Upgrad – Vision and Mission – Successko
upGrad Education Pvt. Ltd. is an online higher education company that provides courses in online mode in the areas of data, technology, and management to college students, job seekers, and working professionals and empowers them to reach their peak potential. These programs are designed in collaboration with top-notch universities like IIIT-B, BITS Pilani, MICA, Cambridge Judge Business School, and many more.
To enhance the learning experience further, a comprehensive ecosystem has been built by upGrad which includes, but is not restricted to, one-on-one mentoring, peer-to-peer learning, industry networking, and expert career guidance. This ensures a holistic approach to gaining the maximum output of the programs offered.
"We, at upGrad, had always believed in the potential of online education being able to transform careers. Hence, the development and adherence to the company's vision statement since its inception in 2015 – 'Building careers of tomorrow'," said Ronnie Screwvala, upGrad founder.
upGrad_Founders
upGrad was founded in 2015 by Ronnie Screwvala, Mayank Kumar, Phalgun Kompalli, and Ravijot Chugh.
Ronnie Screwvala – UpGrad Co-Founder
Ronnie Screwvala is the chairman of the Startup upGrad. He is a well-known personality in the Indian television industry and the founder of UTV Group (now known as Walt Disney India), founder trustee of Swades Foundation, founder of Unilazer Ventures, Board of Advisor AIESEC India, and the founder of RSVP Movies.
He is a great personality, has featured on Esquire's List of the 75 Most Influential People of the 21st Century and ranked 78 among the 100 most influential people in the world on the Time 100 (compiled by Time Magazine, 2009). He was also listed amongst 25 Asia's Most Powerful People by Fortune Magazine and titled the Jack Warner of India
by Newsweek.
Mayank Kumar – UpGrad Co-Founder
Mayank Kumar is the managing director and leads the overall operations at upGrad. Before his upGrad stint, Mayank was the VP of Education at Bertelsmann- Europe's largest media and education conglomerate—where he oversaw the education strategy and its multi-million dollar investments in India. He also served as a Board Member of iNurture—India's number one provider of industry-specific academic programs.
Mayank holds a Bachelor's degree from IIT Delhi and an MBA from the Indian School of Business. He received the coveted BWDISRUPT 40-under-40 Achiever of the Year Award'17 by BW Businessworld. Before joining Bertelsmann, Mayank was a Senior Principal at The Parthenon Group where he advised clients in the education sector on market potential, growth and market entry strategies, investment decisions, revenue & profit uplift strategies. He participated in deals worth USD 1 billion flowing into the education sector and worked with clients from China, South-East Asia, Middle East India, and South America. He also worked at the Tata Strategic Group, advising Tata's strategic direction.
Ravijot Chugh – UpGrad Cofounder
Ravijot Chugh heads career services, product, design, content, delivery, and student success divisions at upGrad. Ravijot was at Housing.com as a product lead and then at the Parthenon Group where he advised multiple companies and private equity investors on due diligence, market-entry, and growth strategy in the education sector of emerging markets across the Asia Pacific, Middle East, and Africa. He also co-founded a social travel startup called 36hrs.in in San Francisco. Ravijot Chugh holds a Bachelors's degree in Computer Science from IIT-Delhi and was part of the Forbes Asia 30 under 30 cohort of 2018.
Phalgun Kompalli – UpGrad Co Founder
Phalgun Kompalli is the head of sales and marketing at upGrad. He heads university partnerships and customer acquisition in addition to sales and marketing. Before UpGrad, Phalgun was a Principal at The Parthenon Group—an education strategy-consulting firm—where he was involved in advising large education conglomerates and investment funds on their growth and investment strategies in the education sector. Phalgun has done significant work in the field of higher education and technology-enabled learning across India, the US, Brazil, Africa, and Southeast Asia. He worked at Opera Solutions before his Parthenon stint. Opera Solutions is an analytics firm providing consultation to Fortune 500 companies on their revenue and cost optimization initiatives through data analytics. He completed his Bachelors in Technology from IIT Delhi.
upGrad is largely built on a direct B2C model of business wherein the consumer enrolls in the program (post receiving an admit) and pays upfront for the enrollment.
For its enterprise business, the company receives payment from companies for training their employees. upGrad earns revenue on contractual basis
upGrad's program pricing reflects its commitment towards getting students placed. 50% of the program fees are collected from the learner only if they get placed after the program's completion. This pricing strategy is the first of its kind in India.
upGrad_Global study partners
WazirX Revenue & Business Model
CRED Revenue & Business Model
JioMart Revenue Model
How Meesho Started
The top competitors of upGrad are –
Unacademy and more.
However, there are certain features that stands out the upGrad apart from its competitors. One of the main USPs is the hand-holding provided to each learner. This practice is called 'student mentorship' and the team behind it is known as 'Student Success' at upGrad.
upGrad aggressively acquired many startups to expand their business exponentially. Talentedge is the latest company that is acquired by upGrad on December 6, 2021. Though the deal value is not disclosed by the company, upGrad has stated in a press statement that the deal is valued around 3-4X of this year's revenues of Talentedge, which was reported to be at around Rs 130 crore.
upGrad has acquired Global Study Partners (GSP), an Australian two-sided marketplace for the recruitment of international students, on November 29, 2021. The company has further promised to invest $16 Mn for a 100% stake in GSP and then allot another $10 mn for its future growth.
upGrad acquired KnowledgeHut, short-term skilling and training courses startup on August 3, 2021. Some other notable acquisitions made by the company were when upGrad acquired Impartus for Rs. 150 crores ( $20.6 Million).
Impartus was a video-learning solutions provider, which is currently operating as a complete subsidiary of upGrad. upGrad acquired Acadview Software in 2018, thereby venturing into the college education space. Before this, the company had acquired Pyoopil Education Technologies, a mobile-based SaaS (Software- as- a- service) product used by companies to deploy online training in 2016.
In 2019, upGrad acquired CohortPlus, India's largest and most active community on product management and data science.
Here's the table mentioned of all the acquisitions that upGrad has seen so far.
Talentedge December 6, 2021 Undisclosed
Global Study Partners November 29, 2021 Undisclosed
KnowledgeHut August 3, 2021 Undisclosed
Impartus Innovations May 24, 2021 $20.22 million
Rekrut India December 15, 2020 Undisclosed
The Gate Academy November 24, 2020 Undisclosed
CohortPlus July 4, 2019 Undisclosed
AcadView October 29, 2018 Undisclosed
Pyoopil Education Technologies Pvt Ltd October 17, 2016 Undisclosed
upGrad Aquisitions – Successko
upGrad conducted its maiden ESOP on July 13, 2021, and in it, the company promised the liquidity of an amount close to $29.5 Mn (Rs 220 crores). The maiden ESOP of upGrad has formed a large ESOP pool of around 13% of the enlarged equity base and is planned to benefit both the early and promising team members of the company.
The inclusive ESOP scheme boasts of having over 600 team members, who share the growth story of the company, consisting of 37 early team members.
The company has further increased its employee stock option program (ESOPs) pool by 28% in the middle of November. upGrad, which has earlier spoken of 17,25,810 options (UPGRAD Education-Employee Stock Option (New) Scheme, 2015) has now made it 22,25,810.
This also resulted in lifting the pool's value by 29%, to Rs 427 crore, which was last reported at Rs 331 crore.
← CDS Bipin Rawat Age, Family, Military Career, Wiki, Biography, and More | Unknown Facts of the Legend CDS Bipin Rawat – CDS Bipin Rawat Biography
Startup Ecosystem Grows rapidly recent years due to less Government Interference : Piyush Goyal (Union Minister) →
CRED Revenue Model (How CRED earns Money)
January 23, 2021 April 18, 2021 Shubham 0
WazirX Business (Revenue) Model | How WazirX makes Money
March 19, 2021 September 17, 2021 Shubham 0
CarDekho Revenue (Business) Model | How CarDekho earns money
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Sunday 30th June 2013 sees the first St Barnabas Grimsthorpe Challenge hit the roads of Lincolnshire, Rutland and Nothamptonshire. Run in aid of St Barnabas Hospice, it is not compulsory to raise sponsorship, you can just donate when you enter online or on the day.
Start and finish in front of the impressive 16th century Grimsthorpe Castle in south Lincolnshire, with the first 5 miles of all routes on a traffic-free tarmac trail through the historic grounds and woodlands of the Grimsthorpe Estate.
After that the on-road routes are not much busier as you turn to the north of the Estate onto the quiet lanes of South Lincolnshire before turning south to Head for the more challenging Rutland and Northants roads.
There are three routes to choose from, 115 miles, 76 miles and 55 miles, with the longest route also being hillier.
There are three feeds on the longest route, two on the medium route and one on the shortest. Post event food will be provided as part of the entry fee. Breakfast, tea and coffee prior to the ride can be purchased on the day.
Sunday 30th June 2013 sees the first St Barnabas Grimsthorpe Challenge hit the roads of Lincolnshire, Rutland and Nothamptonshire. Run in aid of St Barnabas Hospice, it is not compulsory to raise sponsorship, you can just donate when you enter online or on the day. Start and finish in front of the impressive 16th century Grimsthorpe Castle in south Lincolnshire, with the first 5 miles of all routes on a traffic-free tarmac trail through the historic grounds and woodlands of the Grimsthorpe Estate. After that the on-road routes are not much busier as you turn to the north of the Estate onto the quiet lanes of South Lincolnshire before turning south to Head for the more challenging Rutland and Northants roads. There are three routes to choose from, 115 miles, 76 miles and 55 miles, with the longest route also being hillier. There are three feeds on the longest route, two on the medium route and one on the shortest. Post event food will be provided as part of the entry fee.


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Q: Сcleaner начал застревать минуты на 3 при очистке кэша Firefox, причем только в одной вновьсоздаваемой папке С недавних пор CCleaner при чистке начал застревать в этом месте (очищает минуты 3 одну директорию):
C:\Users\Megauser\AppData\Local\Mozilla\Firefox\Profiles\m321gl1b.default\cashe2\entries
Шерстит в логах кучу штук типа 015F601F1117708B3BF1BD57CF8256FBCCB38D20, а после очистки просто удаляет папки cashe2\entries. После того как захожу на сайты Poloniex Bittrex папки с файлами появляются вновь, по-моему после Poloniex они появляются. Суток вполне хватает чтобы CCleaner застревал в этой папке минуты на 3.
Такого раньше не было, а сейчас появилось, это нормально или вирус какой-то взломать меня пытается?


Will it shorten the life of the diode? Thats really all im worried about... As far as heat sinks go, im still looking for a good one I can make at home, time to read around :) Any suggestions?
Tried a 9 volt and its much brighter, it lit the match instantly! But ive heard people suggesting to not use them before although I forgot the reason...any idea on why I shouldnt? In any case, thanks for all the help!
So I guess I'm just confused of what to do with that extra pin...break it off or not?


Choose the Spanish language courses that suit your ability and aspirations. Whether you want to learn Spanish for business purposes, because you're buying a holiday home in Spain, or just want to improve your language skills, we have Spanish language courses to suit your requirements.
Get in touch with me today to find out about my unique 1 to 1 Spanish Language tuition. We'll make an appointment to connect via Skype and you can enjoy the benefits of my Spanish language courses in the comfort of your own home. The 1 to 1 tuition is backed up by on-line videos and course materials. I have more than 10 years' experience of teaching Spanish to people of all ages and abilities, so my courses are interesting and varied.
We base our Spanish language courses on the everyday life activities and conversations of the real world depending on your level of knowledge of Spanish. The teaching approach immerses students into Spanish so they are actively involved in learning and communicating in Spanish.
Why Take a Spanish Language Course?
Spanish is growing in popularity worldwide because of its ever-increasing global importance.
But there are other languages out there, so why choose Spanish?
It unlocks a world of options – With an estimated 470 million native Spanish speakers worldwide, learning the language opens up a huge array of travel options.
Enjoy classic books, films, and TV – One book that is often voted in the top ten of 'greatest ever books' is "El ingenioso hidalgo Don Quixote de la Mancha" by Miguel de Cervantes. Learning Spanish means you can enjoy this and so much more Spanish literature and television.
Expand your opportunities – With Spanish as your second language you open up a vast array of new job opportunities both abroad and locally. Speaking Spanish is highly sought after in business circles, meaning that you won't be stuck for job opportunities.
It isn't difficult – Because written Spanish is almost completely phonetic, it makes it much easier to learn. Many English speakers are quick to learn the basic grammar too!


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Chris Brown ft. Lil' Wayne & French Montana – "Loyal" [LISTEN]
Written By Chris Thomas
Chris Brown knows the his way around gold diggers and philandering with women all too well. In fact, he just dropped a new track dedicated to his experiences called "Loyal."
Here, Brown is joined by rappers Lil Wayne and French Montana, who assist with their best "I can take your girl" raps. "Just got rich/Took a broke n***a b**ch," the crooner chants on the cut. As you can see, it's clearly a dirty game out here.
This release follows the singer's X-Files mixtape, which was mean to whet the appetites of fans who are anticipating the long-awaited X. That should change sooner than later, as Brown's latest body of work is now slated for an early 2014 release.
Until then, lend an ear to "Loyal" below and share your thoughts via the comments.
[via DJ Absolut]
"Loyal" French Montana lil wayne X


I am starting with a triple clamp assembly from a CBR929RR. Head and fork tubes are carbon fiber. Spacers and steering bearings are 3D printed. I plan on using an hydraulic master cylinder to drive the front brake potentiometer. Will post more pictures as I make more progress.
This will be very interesting to see how you progress with this and how well it will work, Uberslug.
Is this something your doing as a one off personal project or something your planning to build and sell to others in the future?
Good luck with this project mate.... I'll be following your progress closely.
they see carbon pattern they go crazy !
Why not act on a load cell instead of a pot with that master cylinder? Potentiometers are useless. At the very least magnetic resistance sensors are a great alternative.
what about a single pot break caliper (easily compatible with any break lever) with a load cell like people are suggesting. It could be mounted anywhere on the controller.
You may want to speak to DoubleDragonCC as he is guy when it comes to custom controllers! And he is even currently working on a hydraulic breaking system.
I have added the handlebars and brake levers.
Here is my concept for the front brake potentiometer.
The red unit allows one to convert a cable clutch lever to a hydraulic lever. The barrel to the right houses a small progressive rate spring and the rod on the left pulls / pushes on a linear potentiometer. The lever should approximate what one gets on a game controller. I will eventually source a brake caliper and a compatible pressure transducer but I am still in the proof of concept stage.
I have a set of levers both with master cyliders for brake and clutch but my 100psi transducer is giving me problems, think I brike the membrane? I will let you know results as I test different transducers.
Mock up of Shift Switches with Rear Set.
Rethought the brakes and picked up a couple of used CBR600RR Rear Brake Calipers and a Master Cylinder.
Initial frame layout using old 8020 extrusion I found in the garage.
Very interesting build anyway !
Nice work man. Can't wait to see the end product.


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Big Sur Photos
Fine Art Photography of Big Sur California
What is Big Sur
Big Sur is a scenic area located on the Central Coast of California between San Simeon and Carmel (Monterey), approximately 300 miles north of Los Angeles, and 150 miles south of San Francisco. Big Sur is a place of rugged beauty of grandeur proportions on the edge of California and the "Western World".
What name Big Sur mean
The name Big Sur came from Spanish "El Sur Grande" or "El País Grande Del Sur" – "The Big South" or "The Big Country Of The South", that's what locals called this unexplored wilderness area along the coast South of Monterey, which many would agree is one of the most beautiful places in the World.
How big is Big Sur
Surrounded by Ventana Wilderness area and the three million acres of the Los Padres National Forest, and accessible only from Highway 1 (Pacific Coast Highway – PCH), which runs along the spectacular Pacific coast for over 90 miles, Big Sur is mostly majestic wilderness, with State and National Parks and a few small villages along the main road.
Highway 1 (PCH)
Declared California's First Scenic Highway PCH (Highway 1) is being considered "state of art" itself. It started in 1872 with a wagon road built south from Monterey to Bixby Creek. Modern highway construction began in 1922, took over 20 years (the present highway was officially opened in June of 1937), and was very expensive to build due to extremely difficult area it goes through.
Pacific Coast Highway is a World class road, and one of the best maintained, but still some parts of it get closed sometimes after being washed away by winter rainstorms. PCH is not the easiest road to drive because of hundreds of curves that contour the mountain ridges, but it provides driving experience unsurpassed in natural beauty, grandeur and exhilaration.
What's in Big Sur
From San Simeon (Hearst Castle) on the south end, the scenic drive goes climbing up, above the clouds, and drops down to where the ocean meets the land, and then up again, with mountains, creeks, waterfalls, patches of redwood forest wilderness and ocean beaches all the way to Carmel.
A few very small developed areas along Highway 1 with cafes and art galleries, campgrounds and private houses scattered in the mountains, and the highway itself is all that exist here of "civilization". The rest is just majestic wilderness of grand proportions and rugged beauty, work of elements and powers of Nature.
Big Sur history
At the turn of the last century Big Sur sustained a booming redwood lumbering industry, and the first permanent settlers arrived in Big Sur around 1930's. Some of their descendants still live here, but the whole area population is smaller today than it was back then, with total number of houses today being a little over 600.
Big Sur is a place dearly loved by travelers, philosophers, writers, poets and artists. Among people who epitomize it in their books, two American literature icons: Henry Miller and Jack Kerouac, made Big Sur known to a larger audience. Today this natural marvel attracts thousands of people from around the World, many of whom visit this place more than once.
National Geographic magazine named Big Sur as one of the "50 Places of a Lifetime" in "The World's Greatest Destinations." Big Sur is also home of the "Best Marathon in North America" and the "Best Hotel in North America" – Post Ranch Inn, which also once was named "Number One Hotel in the World."
When is the best time to visit Big Sur
The best time to visit Big Sur is during the spring and fall. Wild flowers and abundant flora and fauna make springtime especially attractive, while autumn provides gorgeous foliage colors and more contemplative environment. Coastal fog cools the summer mornings, but it's usually gone by early afternoon. Winters are mild, and rainy days are mixed with periods of bright sunshine.
So visit, drive safely and enjoy this scenic paradise called Big Sur.
Enter Gallery
Three new natural monuments in the province of Malaga that you can visit in Puente de Mayo
Big Sur Books
Big Sur Information
Big Sur – 90 miles of beautiful scenery and beaches
Big Sur Photos | 2018 ©


Advocates Working to End Harsh School Discipline That Leads to Dropping Out, Jail | Racial Justice NOW!
Activists concerned about disciplinary policies that force students out of school and into the justice system will gather in cities across the country this week to make their case for reform.
In Boston, they plan to fan out to ask their peers about their experiences with school discipline, results they will pass on to city school administrators.
In Miami, the community will gather for a Forum on Black Lives focused on local county and school board races to ensure school discipline is on the agenda.
And in Dayton, Ohio, organizers will release report cards that show how every school system in the state is performing on disciplinary measures, data that's collected but not publicized by state officials.
The events are part of the Dignity in Schools Campaign's 7th annual Week of Action to raise awareness about school pushout.
The campaign's supporters argue schools are too quick to punish students harshly, especially students of color, students with disabilities, and students who identify as lesbian, gay, bisexual and transgender.
In Pittsburg, supporters of the Solutions Not Suspensions Campaign spoke on Monday at a school board meeting about the importance of ending school push out.
Suspensions and expulsions can cause students to leave school and lose direction in their lives, ultimately ending up in the criminal justice system, a phenomenon known as the school-to-prison pipeline, they say.
End paddling and other physical punishment.
Since the campaign launched a decade ago, communities are increasingly aware of the importance of paying attention to disciplinary policies, said Nancy Treviño, a spokeswoman for the campaign.
The federal government has released recommendations on discipline, cities and states have adopted new policies and media organizations are more likely to tell the stories of communities concerned about school pushout.
But, much work remains to be done, organizers say. The politics of every community vary, making the implementation of policies that stress alternatives to suspension or promote restorative justice the next hurdle for advocates, Treviño said.
Ten years ago, school administrators had to be introduced to concepts like school pushout, said Ruth Jeannoel, lead organizer at Power U Center for Social Change in Miami. Now they know more but still sometimes have to be prodded into following through on proposed policies or informing students of their rights, she said.
"There's a lot of work that has happened, but of course there's a lot more to do," she said.
In Boston, advocates long have enjoyed a good relationship with city school officials, said Tina-Marie Johnson, a youth worker at Youth Organizers United for the Now Generation.
Each year, advocates share their findings from the surveys youth take of their peers to make the case for where reforms still are needed. And organizers update the survey each year, to be sure they're addressing new issues that may have arisen and capturing as much data as they can about whether some populations of students face harsher consequences than others.
"We want the conversation to be inclusive of all members of the school community, especially those who [are] affected the most," Johnson said.
Hashim Jabar, director of the West Dayton Youth Task Force, said data is critical for making the case to school, local and state officials, but he also wants families to spend time understanding what's happening in their local schools.
"The community as well needs to know more and stand up for themselves and take the information and use it to be empowered," he said.
In additional to the local events, a national event with speakers and music is planned for tonight in Pittsburgh, with a livestream available for those in other locations.


The Beekman Group ("Beekman"), a leading lower middle-market private equity firm based in New York, is pleased to announce that it has promoted Jonathan Tanenbaum to Vice President and hired Will Manderscheid to join its team as a Senior Associate. These professionals will focus on transaction execution and portfolio company management across Beekman's industry verticals.
"Jonathan has been an exceptional asset to our team since joining Beekman in 2015, and we look forward to his continued success as he adds value in this new role across the portfolio. We are also excited to welcome Will and believe his past experiences and insights will be complementary to our investment team, especially in the industrial and business services sectors," said John G. Troiano, Managing Partner & CEO.
Beekman is committed to investing in its people and infrastructure. Over the past two years, the firm has hired several seasoned professionals to build out its platform and provide value-added resources to its portfolio companies, industry advisors and portfolio management teams. Earlier in 2017, Beekman launched an Associate Program with its first two associate hires, and in late 2017 the firm hired Chris Artinian to join as a Managing Director covering Beekman's consumer industry vertical, with a special focus on restaurant, hospitality, and food and beverage investments.
Beekman is proud of its human capital and culture, and believes its people and management teams are the foundation to the success of the firm. Beekman anticipates continued success for all professionals as it grows its assets under management and its private equity investment platform.
Jonathan Tanenbaum, Vice President – Mr. Tanenbaum is responsible for transaction execution, financial analysis and portfolio company management. Mr. Tanenbaum joined the firm in 2015 and is involved in the firm's consumer and restaurant portfolio companies. Prior to joining Beekman, Mr. Tanenbaum worked at Sun Capital Partners, a middle-market private equity firm, in its New York office. Prior to Sun Capital, Mr. Tanenbaum worked at J.P. Morgan Securities in its Diversified Industrials and Leveraged Finance investment banking groups. Mr. Tanenbaum received his Bachelor of Arts degree in Economics from the University of Chicago, and earned his MBA from the Wharton School at the University of Pennsylvania.
Founded in 2004, The Beekman Group is a leading private equity firm based in New York City, dedicated to bringing financial and operational resources to lower middle-market companies. Beekman's team consists of experienced private equity professionals, as well as a select group of operating executives who are leading executives in Beekman's targeted industry segments. This approach to investing is the cornerstone of Beekman's investment strategy – creating value through accelerating growth in partnership with small and middle-market management teams. For more information on The Beekman Group please visit: http://www.thebeekmangroup.com.


Enjoyable learning with the kids is easy right now. There are many sources with useful material which can make the teaching and learning more adorable. Here, we have prepared some materials for learning the number especially the number 10. Number 10 worksheets will help the kids to make their handwriting better. It is available on high quality and definition. Feel free to save and print it for your kids.
When the kids have mastered the letter 10, they can easily make the other numbers. Here are more number 10 worksheets for your kids. You can print it in the large size and help the kids to do the job. Make the kids do more practice to make their handwriting better.
While the kids do the number 10 worksheets, they will also learn about counting the pictures in it. There are some picture fill in the space around the number 10. You can ask amount of the things so that the kids will be able to count things.
Adorable, isn't it? You can help the kids mastered the number 10 easily. The cute 10shape will be memorized by the kids fast. See you on the next post.
Number 10 Worksheets for Children on Kiddo Shelter. This content presented by Miss Clark on 28 March 2017 at 1:02 pm. If you feel this post of Number 10 Worksheets for Children is useful for you, feel free to share this nice Tracing Kiddo Shelter content for your kids activities.


Piaget Polo FortyFive watch, 45 mm. ADLC-treated titanium case and ADLC-treated steel gadroons. Dial with luminescent hour markers. Sapphire crystal case back. Manufacture Piaget 880P PVD ultra-thin self-winding mechanical chronograph movement with small seconds, chronograph flyback function, date and dual time zone.
If the memory of the past does indeed serve to write the future, the Piaget Polo FortyFive watch is certainly a vivid illustration of this maxim. An audacious adaptation of the famous Piaget Polo watch, this resolutely sporty watch creation has a diameter of 45 mm, reminiscent of the 45-minute duration of a polo match. It has a shape carefully designed to ensure maximum comfort and presents a combination of materials that is a first for Piaget, with an outstanding finishing for good measure. This titanium model coated with a surface treatment known as ADLC is presented in a strikingly beautiful black matt case with polished satin finishes. It matches magnificently the black ADLC-treated injected rubber strap decorated with steel gadroons and fastened by a buckle with a summer/winter adjustment. Water-resistant at 100 metres, this exceptional timepiece is equipped with an 880P self-winding chronograph movement with flyback, dual time zone and large date features, displaying its functions on a black dial.


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Rashida Jones, David Oyelowo join cast of Apple TV+ original 'Wool'
Posted: September 22, 2021 10:53PM
in iPod + iTunes + AppleTV edited September 2021
Apple recently signed Rashida Jones and David Oyelowo to the cast of upcoming Apple TV+ dystopian series "Wool," adding to a list of big names already attached to the production.
Jones and Oyelowo join Tim Robbins and Rebecca Ferguson in the show based on Hugh Howey's New York Times bestselling "Silo" series, reports Deadline.
"Wool" takes place in a ruined world where people are forced underground to survive. The story revolves around a community living in a silo that goes hundreds of stories into the earth.
Oyelowo will play Holston, the Silo's sheriff, while Jones is set to play his wife Allison. Allison works alongside Ferguson's character the silo's IT department, which is headed by Bernard (Robbins).
Jones, perhaps best known for her roles in "The Office" and "Parks and Recreation," recently starred in Netflix comedy "#BlackAF" and lended her voice to Fox's "Duncanville." She was the lead in Apple TV+ original "On the Rocks," directed by Sofia Coppola and co-starring Bill Murray.
A seasoned British actor with multiple credits to his name, Oyelowo put in a commanding performance as Martin Luther King, Jr. in 2014's "Selma," directed by Ava DuVernay.
"Wool" will be penned by Emmy-nominated screenwriter Graham Yost ("Band of Brothers," "Justified") and directed by Academy Award nominee Morten Tyldum ("Defending Jacob," "The Imitation Game"). Ferguson, Yost, Tyldum and Howey will executive produce alongside Remi Aubuchon, Nina Jack and Ingrid Escajeda.
Hank2.0 Posts: 150member
"Wool" takes place in a ruined world where people are forced underground to survive. The story revolves around a community living in a nose-down buried train that goes hundreds of cars into the earth...Wait! have I seen this before?


The other night my mom and I decided to have a much-needed girls' night and, having heard good things about The Salty Pig near Back Bay Station, we decided to give it a go. Although it is technically one of what I think is way too many pig-parts-are-now-cool charcuterie and booze places, with a very generic pig-parts-are-now-cool charcuterie and booze place name (in Hong Kong, I went to an almost identical one called "The Salted Pig"), I enjoyed the vibe at TSP and thought it unique among the others, at least those here in Boston.
The dining room is informal and laid back, yet glossy and chic, with neat high-top chairs and comfy booths from which to watch the action across the bar – pizza dough being flipped and shoved into the oven (gas-fired, but whatever…), cured meats, chili peppers and garlic cloves swinging from the kitchen ceiling, a bartender mixing up some of their signature cordial cocktails (more on this later) and delicious entrees flying out of the semi-open kitchen. The staff seems very friendly and sometimes slightly awkward in a cute, quirky and humble way. All in all it's a great place to grab a bite with someone you love and catch up on how your lives have been going lately.
We got The Hybrid, which was made of Pamplemousse (grapefruit liqueur), Aperol, orange juice and topped off with sparkling wine. It was light and fruity, with the grapefruit liqueur toning down the sweetness of the orange, while the Aperol brought a beautifully bitter finish to the sip. The sparkling wine lifted the cocktail up and made it refreshing and light, despite this bitter finish.
We also got The Orchard, which was made with Downeast cider (a yummy crisp thing with no preservatives added), Creole Shrubb (a slightly bitter rum-based orange liqueur) and bitters. It was sweet but not over-the-top, as many poorly made cider-based drinks tend to be. It had a nice acidity from the dry cider and a spicy, peppery quality from the orange liqueur. Perfect to eat before the meal to get set the hunger pangs going.
The menu at TSP is divided into the major sections, which basically represents the two different types of dining at the restaurant. One can go with the snacking option and select meats, cheeses and accompaniments and build one's own charcuterie and cheese board to pick at while enjoying a cocktail or two. One can also choose a more heartier dinner entree and either share a rustic, farmhouse-style pizza (their list includes one called The Salty Pig, which features daily "pig parts," mustard and pale ale vinaigrette and looks particularly delicious) or choose one of their meaty pastas or tavern-style seafood options (mussels with bacon and shallots, grilled calamari, etc.). As my mom and I are dainty little things with bird-like eating habits, we decided to get a board of little numnums. We listed off our selections to the waitress who memorized it without scribbling anything on a dupe, and she managed to get us almost exactly what we ordered, with some changes that we actually did not mind at all.
From the meats, we chose the Chicken Liver Mousse, made in the Salty Pig kitchen. It was incredibly smooth, buttery and cool, melting onto the roof of my mouth instantaneously and coating my tongue with its metallic, innard-y sweetness. It was sprinkled with fennel pollen, which added a nice herbal zing and some coarse sea salt, which brought the natural sweetness of the mousse to the forefront. Spread over crunchy toast points, it was a great bite. We also ordered the Pork Rillette, also from the Salty Pig kitchen, made from shoulder and belly. It was smooth, with tender shreds of meat held together by the wonderful fat it was cooked in, and formed into a spread-able paste. It was flavored with coriander, fennel and orange, which took away from the extreme saltiness of the pork and brought the rillette into a more neutral salty-sweet realm. Next, we had some Finocchiona, a dry-cured pork-based sausage, flavored with garlic and fennel. This went particularly well with the house-made foccaccia-type, slightly sweet bread that our waitress brought out before the meal along with some mature olive oil of good quality. The whole-grain, spicy mostarda, which we actually did not order but which was very much appreciated, went well with the finocchiona and added a face-unclogging heat to the board.
From the extremely well put together "Stinky Cheeses" list, we selected the aptly named Bonne Bouche Goat Cheese, from Vermont Butter & Cheese Creamery. It was actually not on the menu on the night we went, but was recommended as an alternative to the Valençay-style ash-coated goat cheese Bonaparte, which is usually featured on their menu. Ash-coated cheeses are great because the thin layer of dark, pulverized ash in the rind stands out strikingly against the milky white interior of the cheese, giving it the aesthetic appeal and the artisanal feel that is a key aspect of stinky cheeses. The ash also protects the soft cheese from forming a thicker, coarser rind that would otherwise crust over the soft cheese inside and overpower it with its mold. The cheese stayed perfectly creamy, almost completely liquid on the inside and gradually firmer towards the exterior. The flavor was nutty (as is characteristic of goat cheeses), piquant and slightly citric. The acidity, however, was balanced out by the ash rind. The cheese was perfect spread over toast points and drizzled with a bit of the Smoked Shallot Marmalade, which had a smokey, grilled flavor that reminded me of smoked eggplant. The marmalade was gooey and moist, with shreds of tender sauteed shallot, the sweetness of which went very well with the pungent cheese.
The unexpected stars of the board were the Charred Shishito Peppers, which I highly recommend ordering as a complement to any of the meats and cheeses. The peppers were very thin-walled and thus charred very nicely, becoming tender but still maintaining a bite. The flavor was mild and vegetal, mixed with some smokiness from the char and sweetness from the caramelization of the exterior. There was a very mild heat at the end of each bite, though, which made them practically addictive. The peppers were warm and went well with some of the cool elements of the dish.
Also thrown on the board were some thin ribbons of cucumber, lightly pickled in sugar and vinegar, and some green, as well as kalamata olives for an extra bit of acidity and freshness.
To follow up on drinks, we tried the Yellow Bellied Monk, which was made with Yellow Chartreuse, Lillet, and yuzu. Although I really liked the name of the drink, I didn't really care for it because it was a bit too mild in flavor for me. The Yellow Chartreuse was very subtle, almost vegetal tasting and the yuzu added only a very subtle acidic note, which didn't really stand up to the greenness of the former. The Lillet didn't pack as powerful a punch as I was expecting and while volume-wise it was the base of the drink, it didn't add too much flavor.
And lastly, the Bitter & Alone. Fernet, Jaeger, Unicum, Limet, Becherovka – these are some of my favorite things. As my life practically revolves around food, a bitter digestif at the end of a meal is something I appreciate very much as an aid to breaking down the food in my belly. This last drink was Becherovka-based, diluted with some fresh fruit juice whose fibrous pulp made the drink nice and thick, sweetened with floral honey and spiced up just a bit with Peychaud's bitters, which has a mild floral flavor that went very well with the herbal zanggg of the Becherovka. An orange rind thrown in for some extra citric aroma.
And for dessert, a Clafoutis, made with ricotta cheese and topped with kumquat marmalade and Marcona almonds. I'm not really sure why they called this a clafoutis, since the latter is actually a French dessert with a flan-like batter which always has cherries baked in. It isn't even technically a flaugnarde, because the batter is not smooth and eggy. But whatever this was (more like a revamped cheesecake), it was delicious. The ricotta batter was coarse on the tongue but altogether pretty smooth and melty, warm and comforting. It was flavored, I think, with honey or french vanilla, because it had a nice clean, floral element in its flavor. It was topped with a kumquat marmalade whose thick, syrupy texture added decadence to the dish, while the acidity of the fruit harmonized with that of the cheese. The almonds added a nutty, oily element and additional sweetness, as well as a textural contrast (crunch).
The Salty Pig may well become one of my new favorite low-key hangout spots. It is relatively close to my apartment, their cocktails are inventive and the menu options are perfect for a nibbler such as myself.
February 3, 2013 in BOSTON.
great foodie blog I just discovered!


The Portland Psychotherapy Clinic, Research, & Training Center is offering a one-year clinical/research fellowship to begin in the late summer of 2019. The position is flexible depending upon the match between the interests of the fellow and the needs of the center.
1. Anxiety disorders track – The anxiety disorders track focuses on learning structured time-limited treatments (based on exposure principles and acceptance and commitment therapy) for anxiety and repetitive behavior disorders under the supervision of Dr. Brian Thompson. This may include both children and adults. The fellow will also have time set aside for administrative and research activities within an anxiety specialty clinic.
3. Clinical specialty track – This track focuses on the provision of clinical services and the development of the fellow's expertise in their chosen area of focus. Areas where specialty supervision can be provided include: Acceptance and Commitment Therapy (ACT), Radically Open Dialectical Behavior Therapy (RO DBT), PTSD, depression, emotionally-focused couples therapy, and motivational interviewing.
The fellow may have the opportunity to co-lead ACT and RODBT classes/groups.
The ideal candidate will have clinical training in ACT, behavior therapy, RO DBT, or compassion-focused therapy approaches. Clinical fellows will receive at least two hours per week of individual supervision per week, which is sufficient for licensure in Oregon.
Profits generated at Portland Psychotherapy goes to fund the research our center is conducting. This includes dedicated research time for clinician-researchers, students, and a full time research coordinator. Our funding structure protects Portland Psychotherapy from the vicissitudes of grant funding and allows us to focus on furthering science rather than chasing grants. In addition, this also allows our clinicians to operate in a true scientist-practitioner model through opportunities to both contribute to and benefit from research conducted in the center. More information about our unique business model can be found here. A listing of our scientific publications can be found here and our lab homepage can be found here.
We are a collaborative group of skilled clinicians and researchers who work together to provide the highest quality of care to those we serve and to use our work to contribute to the broader scientific community. We all have a shared commitment to using science to address the problem of human suffering. We are motivated to develop and maintain expertise in what we do and are continually training and educating ourselves to excel in our areas of expertise. We are looking to add additional team members who share this vision. We strongly value cooperation and collaboration among our staff. Portland Psychotherapy is also highly committed to affirming inclusivity and diversity. Our center's organizational structure allows us to serve clients with and without insurance, as well as those in financial need through sliding scale and low fee services.
Minimum requirements: Doctoral degree in Clinical or Counseling Psychology. Demonstrated interest in and experience with evidence-based therapies. Minority candidates are strongly encouraged to apply.
This is a full-time position (i.e., 40 hours per week). Stipend for the position is competitive and includes both a base salary and a portion of the income generated by clients seen. Portland Psychotherapy offers a benefits package which includes health insurance, retirement plan, and training funds. Fellows are also able to attend all training events offered through the center for free. Portland Psychotherapy strives to provide its staff with a high level of flexibility and autonomy and supports its employees in developing a sustainable work-life balance. The schedule is reasonably flexible and requires daytime hours. Portland Psychotherapy is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. Persons from historically underrepresented populations including gender, sexual, and racial minorities are encouraged to apply.
Deadline for applications: January 6, 2019. Email curriculum vitae, a cover letter indicating your specific interests in this position, and have three letters of reference emailed directly to:humanresources@portlandpsychotherapyclinic.com. Please indicate which track you are interested in when applying.


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text:
Ninja Gaiden 3 PS3
Label: Tecmo
Releasedatum: 23-3-2012
Korting: 24,43 %
Ninja Gaiden 3 aims to take players on a journey with their hero Hayabusa once more, but this time they'll see more from their protagonist than they ever imagined. For the first time, we'll get a look at the world through Hayabusa's eyes, and find out what drives him to fight, and kill.
At the center of the conflict this time around is a masked man whose motivations and goals are unclear. Through mysterious powers, he changes Hayabusa - and the lines between hero and villain, good and evil, are blurred forever.
Featuring a new story, new gameplay and new modes, Ninja Gaiden 3 marks a new direction in this fan-favorite franchise. Team NINJA will change the way fans think about ninja and Hayabusa in this game, and promise that they'll know what it feels like to \"cut someone down\" through their experiences in the game.
The game will also feature online multiplayer, both co-op and competitive, that will add a completely new experience to Ninja Gaiden. The shadowy world of ninja has never been presented this way, and Ninja Gaiden will never be the same! Pick up the Dragon Sword once more, sharpen its blade and hone your skills. An adventure unlike any other awaits you...
- Cutting Down your Enemy: Through new gameplay mechanics and presentation,
players will feel what it's like to cut through an enemy's flesh and bone, along with the
consequence that comes with it.
- A Hero Unmasked: With a new story and new characters, players will learn more
about Hayabusa's past and present life than ever before. Once seen only as a
mindless killing machine, players will unravel layers of their hero as they see his
motivations and learn about the man behind the mask.
- High-Octane Ninja Action: Built upon the same intense action that the series is
renowned for, Ninja Gaiden 3 will challenge players while still remaining accessible for
players new to the franchise.
- Online Action: A rich and challenging set of online modes are being implemented,
giving players the option to play cooperatively or competitively. New challenges,
characters and missions await those who choose to join the Shadows of the World
Resident Evil, Operation Raccoon City PS3


Over the past two weeks, our community has been subjected to an ongoing series of threatening and harassing messages. These messages have been posted on websites and been e-mailed to a few individuals across campus. The messages have been disruptive to our community and have resulted in understandable concern for our safety and security.


What Does 'Ace' Mean In Volleyball?
Micha Hancock went down in history during the 2012 NCAA volleyball tournament when she had 22 service aces in Penn State's run to the final four. Her final tally broke the NCAA tournament record previously set by three-time Olympic gold medalist and one of the best to play the game, Misty May-Treanor.
How does one become a fearsome server like Hancock and score lots of aces? First, each athlete has to determine his or her best serving style.
The term "ace" refers to when a player serves the ball and the opposing team is unable to pass it. An ace occurs when the ball either hits the ground or is shanked off of a passer making a second touch impossible.
The most commonly used serving styles are topspin, float, and jump serve.
A topspin serve is when servers attack the ball by snapping their wrists similar to how they would when spiking, so that the ball spins and dives to the floor after crossing the plane of the net. This advanced serve requires the ability to aim at a target, and players need control over their strength in order to keep the ball in bounds.
A float serve is more common and is one of the more difficult types of serves for the receiving team to pass. The ball is struck with a firm wrist, almost like you are giving the ball a high-five. It does not have any type of spin on it, causing it to move unpredictably and making it harder for the opponent to determine where the ball is heading.
A jump serve is a high-level serve that is becoming increasingly popular within the volleyball community. This serve looks very similar to a back-row attack. It requires an approach, which means that the server needs to be far behind the line to allow enough room to hit the ball. For a jump float, servers toss the ball after they have started their approach, while a jump topspin serve calls for the ball to be tossed before the approach has been started.
Practice makes perfect, and perfecting your serve can increase your chances of scoring an ace. If you do so, maybe one day you'll go down in the record books.


text:
Tecla San Andres-Ziga
Tecla San Andres-Ziga was the first woman bar topnotcher in the Philippines and the first congresswoman to be re-elected. she had been also a representative to the 3rd and 4th Congresses.
2 Accomplishment
Andres-Ziga was born in Naga City, Camarines Sur on August 23, 1906. She studied in Sta. Isabel College and the Catholic Central School. She is a consistent scholar at the University of the Philippines College of Law, where she eventually graduated with honors.
She received the highest rating in the bar examination in 1930. She was the first woman to obtain such feat and honor. She obtained the highest grade when she took the civil service examination for lawyers in 1937. In recognition of her legal competence, she was asked to serve as one of the legal assistants to the Code Committee that revised the Philippine legal codes. She is one of the founders of the Liberal Party in Albay. She also served two terms in the House of Representatives.
Among the outstanding civic organizations with which she is affiliated are: Women Lawyers Association of the Philippines; Social Welfare Board (SWA-UNICEF Assisted Social Services Project); Special Events Committee, Children's Museum and Library, Inc.; Civic Assembly of Women; Philippine Committee, Federacion Internacional de Abogadas; League of Women Voters of the Philippines; Board of Trustees, Nutrition Foundation of the Philippines; and Eye Research Foundation.
de Guzman,Jovita V.,Vicente A. Santiago,Remedios T. de Leon and Teresita E. Erestain. Women Of Distinction; Biographical Essays on Outstanding Filipino Women of the Past and the Present. Philippines: Bukang Liwayway, 1967.
Retrieved from "https://en.wikipilipinas.org/index.php?title=Tecla_San_Andres-Ziga&oldid=4536"


Sovereign Advanced Technologies strives to be a premier provider of cutting edge communication and low voltage technologies while embracing our beliefs that staying ahead of current trends keeps us all safer, smarter and more competitive. We are committed to creating long-term business relationships with our customers while providing the highest level of service. We recognize the importance of developing technology around people, not people around technology with a goal of providing the best mix of products, services, and support that are available in the marketplace.


Ovarian carcinosarcoma is a rare malignancy associated with a high rate of cancer-related mortality even at early stages. Guidelines for systemic treatment have been difficult to establish because the disease is commonly excluded from prospective clinical trials. Ovarian carcinosarcoma is usually managed as high-grade epithelial ovarian cancer despite major histologic differences. Owing to the rarity and poor prognosis of ovarian carcinosarcoma, salvage treatments and their efficacy have been poorly described.
A patient heavily treated for ovarian carcinosarcoma showed an objective response to an immune checkpoint inhibitor, pembrolizumab. Pembrolizumab in this patient appeared to provide tumor control in multifocal metastatic sites.
Pembrolizumab should be evaluated in prospective trials for the treatment of ovarian carcinosarcoma and further work is needed to identify patients most likely to respond to this type of intervention.
Ovarian carcinosarcoma (OCS), also known as malignant mixed mesodermal tumor or malignant mixed müllerian tumor, is a rare and highly aggressive malignancy that contains both sarcomatous and carcinomatous elements . OCS accounts for 1–4% of all primary ovarian carcinomas . According to an analysis of the Surveillance, Epidemiology and End Results data, the rate of OCS is 0.19 per 100,000 women . Despite the rarity of OCS, it is associated with a high rate of cancer-related mortality even at early stages . OCS typically occurs in postmenopausal women at a median age of 65 years and is staged according to FIGO criteria for epithelial ovarian cancer (EOC) . More than 70% of patients present with advanced stage (stage III-IV) disease at the time of diagnosis . The most common symptoms resemble those observed with EOC, including pelvic and/or abdominal pain, early satiety, bloating, and abdominal distention . OCS often presents as a large tumor with massive areas of hemorrhage and necrosis. The morphological features and biology of the tumor seem identical regardless of its site of origin in the female genital tract .
Several clinical prognostic factors associated with poor outcome have been described, including age, advanced stage at presentation, and suboptimal surgical resection . Other reports indicate that the use of adjuvant chemotherapy may have a clinical benefit, although the limited number of patients in these retrospective studies does not allow definitive conclusions in this regard .
The epithelial component of OCS seems to drive the prognosis and survival characteristics and is usually the dominant histologic characteristic in metastatic sites. OCS has a pattern of spread similar to EOC, with early dissemination to the serosa and peritoneum of the pelvic and abdominal cavity . Despite the lack of specific data, OCS is usually treated as a high-grade EOC despite major differences in histologic characteristics, molecular features, response to systemic therapy, and outcome . Median overall survival was also shown to be significantly decreased in women with OCS (24 months) compared with those with EOC (41 months) . Owing to the rarity of OCS and the poor prognosis, salvage treatments and their efficacy have been poorly described. We describe a patient heavily treated for OCS that had an objective response to an immune checkpoint inhibitor, pembrolizumab.
A 62-year-old woman, who was negative for the BRCA1/2 germline mutation, presented to our institution with abdominal pain in October 2011. She was referred from another institution, where she had undergone a primary suboptimal cytoreduction. Pathologic analysis revealed a carcinosarcoma with a high-grade serous adenocarcinoma component associated with high-grade endometrial sarcoma in the right ovary and fallopian tube, with angiolymphatic embolization. There were also peritoneal implants in the upper abdomen and pelvis. The uterus, left fallopian tube and ovary, and lymph nodes had no evidence of disease; however, peritoneal cytologic analysis was positive for malignancy. Immunohistochemistry of the right ovary demonstrated that the tumor was positive for estrogen and progesterone receptor but HER2/neu-negative.
From April through June 2012, the patient received adjuvant carboplatin (AUC 6) and paclitaxel (175 mg/m2) every 3 weeks for four cycles. In July 2012, she underwent an interval cytoreduction (optimal) followed by treatment with intraperitoneal cisplatin (75 mg/m2) and intravenous (135 mg/m2) and intraperitoneal paclitaxel (60 mg/m2) for six additional cycles. After the end of chemotherapy, she received tamoxifen as maintenance treatment for 4 months. She was observed off treatment for 6 months. In May 2013, retroperitoneal adenopathy was discovered following a serial rise in CA125, which prompted radiographic assessment. She received carboplatin (AUC 5), pegylated liposomal doxorubicin (30 mg/m2), and bevacizumab (10 mg/kg) for four cycles and had a partial response. Paclitaxel was not used again owing to residual neuropathy. In light of localized recurrence and response, she underwent a tertiary debulking procedure with complete macroscopic gross resection. Unfortunately, 6 months later a positron emission tomography/computed tomography study (PET-CT) revealed disease progression in a right retropectoral lymph node, as well as in paraesophageal lymph nodes. She then received cisplatin (35 mg/m2), gemcitabine (800 mg/m2), and bevacizumab (10 mg/kg), but had disease progression.
From April 2014 through December 2015, the patient received various treatments for platinum-resistant disease: pemetrexed, nab-paclitaxel, megestrol, capecitabine, and vinorelbine. The metastatic sites were predominantly lymphatic and peritoneal. Despite the extensive pretreatment, she remained largely asymptomatic and had a good performance status. However, owing to disease progression, in January 2016 she initiated treatment with pembrolizumab (200 mg every 3 weeks). Unfortunately, there was not enough material to test the status of microsatellite instability, mutational load, or PD-L1 expression in the tumor. Also, the tumor was not analyzed for druggable mutations due to lack of insurance coverage. After the third cycle, she developed thyroiditis grade 1 but no other adverse events. After the fourth cycle, PET/CT showed objective partial response in the left external iliac lymph nodes (Fig. 1), as well as in the right-posterior pectoral lymph node conglomerate (Fig. 2). Another major site of metastatic disease was the right retropulmonary lymph nodes. With the goal of increasing local control and potentially causing an abscopal effect, she underwent radiotherapy (24 Gy in three fractions of 8 Gy). She then received an additional four cycles of pembrolizumab. Unfortunately, disease progression was discovered in the liver shortly thereafter. She received olaparib (400 mg twice per day) for 2 months but without response, and she died in October 2016.
In the past few decades, overall survival has not improved for women with OCS; the median overall survival is less than 2 years. Currently, there is no clear evidence to establish consensus guidelines for systemic management of OCS .
Published data evaluating the benefit of chemotherapy are scarce, and treatment recommendations are generally based on a few nonrandomized prospective studies and some retrospective analyses. Adding to this difficulty is the common exclusion of patients with OCS from prospective therapeutic clinical trials. Active agents given to patients with OCS include carboplatin, cisplatin, ifosfamide, paclitaxel, doxorubicin, and dacarbazine [1, 10]. Common treatment combinations include platinum plus paclitaxel and platinum plus ifosfamide, although the benefit of multiagent chemotherapy over single-agent chemotherapy is unclear. The overall response rate (ORR) to platinum-based chemotherapy for patients with OCS varies between 25 and 70%, whereas median overall survival ranges from 8 to 16 months . There is little evidence regarding the effectiveness of second-line therapies. In a study of single-agent ifosfamide, an ORR of 17.9% in patients with recurrent disease was recorded . Owing to the high rate of recurrence, even for those with early-stage disease, adjuvant systemic therapy is generally considered, although there is no clear consensus on the standard first-line therapy in the adjuvant and metastatic setting .
Several studies have verified the role of molecular signaling pathways in the treatment of OCS. OCS most frequently contains high-grade serous components, which often contain a TP53 mutation, and the precursor lesions may originate from normal-appearing fallopian tube epithelium that contains a TP53 signature . Given the poor response of OCS to standard available therapies, researchers have sought insight from molecular characterizations such as next-generation whole-exome sequencing . Unsurprisingly, given the high rate of serous adenomatous components in OCS, the most common alteration is in TP53 . Other alterations described include mutations in H2A and H2B, deletions of TP53 and MBD3, and amplification of chromosome segments containing PIK3CA, TERT, and MYC. However, few of these mutations are directly druggable .
Nevertheless, some EOCs have been known to induce a strong immune response characterized by high tumor T-cell infiltrates. As such, immune checkpoint inhibitors and combinations with chemotherapy, anti-angiogenesis agents, poly (ADP-ribose) polymerase (PARP) inhibitors, and other immune active compounds are under active investigation. Immunologic effector cells may be blocked by inhibitory regulatory pathways controlled by specific molecules often called immune checkpoints. These checkpoints serve to control or turn off the immune response when it is no longer needed to prevent tissue injury and autoimmunity . Immune responses to ovarian cancer appear to vary by histologic subtype; high-grade serous cancers are most likely to be associated with a prognostically favorable tumor-infiltrating lymphocyte response. Classification of various histologic subtypes of ovarian cancers on the basis of tumor-infiltrating lymphocytes and PD-L1 expression revealed that type I patterns were more common in high-grade serous cancers and type IV patterns predominated in other histologic subtypes .
A phase Ib trial evaluated the safety and antitumor activity of pembrolizumab, an anti-PD-1 antibody, in patients with PD-L1-positive advanced solid tumors. One of the 26 patients with advanced EOC obtained a complete response and two patients experienced a partial response. The ORR was 11.5%, and the most common adverse events reported were fatigue, anemia, and decreased appetite . Pembrolizumab has been studied in various scenarios in EOC: neoadjuvant setting, maintenance treatment, and recurrent or metastatic disease .
Another anti-PD-1 antibody, nivolumab, has also been studied in ovarian cancer. In a phase II trial, nivolumab was administered in patients with platinum-resistant EOC. Two complete responses were observed, as well as one partial response. The ORR was 15%, and the disease control rate was 45% . Avelumab, a fully-humanized anti-PD-L1 IgG1 antibody, was studied in a phase I trial in patients with recurrent or refractory EOC. The ORR was 9.7% and the disease control rate was 54% . A summary of the results of single-agent trials of PD-1/PD-L1 inhibitors is presented in Table 1. Ongoing studies are also evaluating the role of an anti-CTLA-4 antibody. Independent from the prognostic significance of PD-L1 expression, PD-L1/PD-1 receptor B7/CTLA-4 interactions are important immune escape mechanisms, allowing tumor progression .
To the best of our knowledge, this case report represents the first data on the use of pembrolizumab in OCS. The objective response in our patient suggests that OCS, like EOC, is an immunogenic malignancy. Interestingly, our patient was heavily pretreated with multiple locoregional and systemic therapies. It is unknown whether radiotherapy may have contributed to the objective response according to the suggested abscopal effect . The biologic phenomenon underlying this effect is not completely understood, but it may be mediated by immunologic mechanisms .
In conclusion, pembrolizumab in this patient appeared to provide some tumor control in multifocal metastatic sites, despite the effects being short-lived. OCS should be evaluated in prospective trials and further work is needed to identify patients most likely to respond to this type of intervention.
We would like to thank the Department of Scientific Publications of MD Anderson Cancer Center.
RLC is supported by CPRIT RP120214, the Ann Rife Cox Chair in Gynecology, Judy Reis/Albert Pisani, and the MD Anderson ovarian cancer research fund. All other authors have no funding to declare. No funding was received to publish this manuscript.
GZDM and CMA contributed to write the manuscript. GZDM, CMR, RLC and FCT edited the manuscript. All authors read and approved the final manuscript.
Ethics approval was obtained from the ethics committee's of Hospital Beneficencia Portuguesa de Sao Paulo.We had consent to participate under the 'Ethics, consent and permissions' heading.
We obtained consent to publish from the legal parent to report individual patient data.
RLC has clinical research funding from Merck, AstraZeneca/Medimmune, Genentech/Roche, Novartis, Clovis Oncology, Abbvie, and Janssen pharmaceuticals. All other authors have no competing interests to declare.


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In this article I will show you my favorite one piece swimsuit floral for these summer season.
I think you´ll agree with me when I say: With plenty of swimsuit options out there It´s REALLY hard to choose the right one according to your Body type and Skin. You may feel frustrated.
No matter your body shape we have found the Best one piece swimsuit floral that makes you feel the best when you hit the beach.
The world of swimsuit is an exciting, ever-changing one – there's always a new brand, fresh trend or never-before-seen style to look forward to. Whether you're looking for a new look for the resort or a swimsuit to sunbathing on the beach in, swimsuit shopping can sometimes be a bit of a drag for most women, especially if you have no idea what to look for.
Ladies, these are the best one piece swimsuit floral that we're excited about right now, and you should be too! Why ?
Because these one piece swimsuit floral are THE BEST! Designed with flexible, soft, and cool blend of fabrics that offer a comfortable and flattering fit.
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Nitty Gritty Dirt Band – "The Hits, The History & Dirt Does Dylan" Live at The Kent Stage
Nitty Gritty Dirt Band – "The Hits, The History & Dirt Does...
Kent, 44240, Ohio, United States
Nitty Gritty Dirt Band makes their return to The Kent Stage for their "The Hits, The History & Dirt Does Dylan" Tour on Friday, March 10th, 2023 at 8 P.M.!
Tickets for the show go on sale beginning Friday, December 9th at 10 am EST at kentstage.org or you may purchase at our New Box Office anytime the doors are open. Located at 175 E. Main St. in Downtown Kent, Ohio 44240.
Ticket Prices: Gold Circle $73, Floor $58, Balcony $48