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Minster stuns Kirtland in epic state championship game
COLUMBUS—Minster scored 13 points in a 34-second span late in the fourth quarter to defeat Kirtland, 46-42, in the Ohio High School Athletic Association's Division VI state championship game in front of 7,361 at Ohio Stadium on Friday.
The loss snapped Kirtland's 29-game winning streak.
"It was a fantastic football game," said Kirtland coach Tiger LaVerde. "These guys played their hearts out. Both teams played their hearts out. The ball didn't bounce our way at the end and we didn't get stops when we needed them. What a football game. And I love these guys right here. I'm going to miss them. They're unbelievable kids and they're great football players."
Adam Hess' 3-yard touchdown run gave the Hornets a 42-33 lead with 4:18 left in the game. The Wildcats, who racked up 469 yards of offense, responded with an 11-play, 65-yard scoring drive capped by Evan Huelsman's 2-yard touchdown run. Jason Schultz added the extra point to pull the Wildcats to within 42-40 with 1:56 to play.
Schultz then recovered his own onside kick attempt after it bounced off a Kirtland player and the Wildcats took over at the Kirtland 49.
"I was to the right of the ball where it was kicked," said Kirtland quarterback Sam Skiljan. "I thought we were going to get it. It took a bad bounce. It happens. It hurts a lot."
Matthew Finkler sacked Minster quarterback Josh Nixon on first down but Nixon threw a 51-yard touchdown pass to all-Ohioan Eli Wolf on the next play and Schultz added the extra point to put the Wildcats on top 46-42 with just 1:15 remaining in the game.
"We were in man-to-man, they ran a crossing route and they caught it," LaVerde said of Nixon's touchdown pass to Wolf. "The guy broke a couple of tackles and scored."
The Hornets started their final drive at their own 19 and moved to the 40 but Skiljan was stopped short on 4th-and-3 and the Wildcats took a knee to win their second state title overall and first since 1989.
"That was two really good football teams competing," said Minster head coach Geron Stokes. "It came down to the last second. Credit Kirtland. What a run for those guys. They're as tough and physical a team as we've played all year. Credit our kids and the resiliency they showed. We did not belong here early on in the year. This is the most improvement I've seen out of a team, a group of kids that bought into being better. This is awesome."
Kirtland led 21-20 after the first half, which saw five lead changes.
Minster scored on its first possession of the second half but the Hornets scored the next 14 points to take a 35-27 lead. The 8-point advantage was the biggest of the game for either team.
Despite Nixon throwing for 417 yards and four touchdowns, Kirtland outgained Minster, 471-469.
Hess carried 39 times for 164 yards and two touchdowns and Skiljan ran for 95 yards on 20 carries. Skiljan completed 7-of-14 passes for 145 yards with three touchdown passes. Finkler caught four passes for 120 yards and two scores and Evan Madden had two catches for 28 yards and a touchdown.
Kirtland's senior class closed out their careers with an overall record of 58-2, a 29-game winning streak and two state championships in four straight state championship game appearances.
"We wouldn't be sitting where we are without these guys," LaVerde said. "Not only are they good workers in the offseason, but they're just great kids. They're humble. They're kind. They're good people and they're going to be great people when they get older. And I'm really going to miss them."
Both of Kirtland's losses over the past four seasons were to Midwest Athletic Conference opponents. Coldwater beat Kirtland 10-9 in the 2012 championship game.
"All those teams from the MAC, they are physical and they are going to play tough football," LaVerde said. "We knew coming into this game that they would not quit, and unfortunately for us, they made the plays. Their quarterback played very well for them, and that was just a great football game to be a part of."
The MAC has now won 108 state championships with two teams, Coldwater and Marion Local, playing for titles on Saturday.
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Tigers lock up first conference title since 2015
With a 59-25 win at Orange on Wednesday, Chagrin Falls' girls' basketball team secured its first Chagrin Valley Conference title since 2015.


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Geese roam in the Parksville Community Park. - File photo
City of Parksville plans for annual Canada goose harvest
Geese are shot in the head with a bolt gun, which kills them instantly
Karly Blats
The City of Parksville has requested council approve $35,000 in the 2019 budget for goose management, in order to proceed with immediate egg addling and acquire necessary permits to begin a harvest.
In June 2015, Parksville council adopted in principle 38 recommendations contained in a goose management strategy for the Mount Arrowsmith Biosphere Region, prepared by the Guardians of Mid-Island Estuaries Society.
A key recommendation of the strategy is to humanely reduce non-migratory resident Canada goose populations in the city to a level that prevents conflict between geese and human activities and reduces the ecological damage to local estuaries.
The first time the city had Canada geese killed as part of their three-year program was in 2016, with 484 birds taken from the Englishmen River estuary and killed.
In September 2018, following a presentation by the Guardians, council passed a resolution stating that the 2018-2022 financial plan be amended to include funding in the amount of not more than $35,000 per year for three years (from 2019 to 2021).
At an April 1 council meeting, Deb Tardiff, city manager of communications, said because the 2019 budget will not be approved for a few more weeks, staff is bringing forward the report prior to budget approval to get started on the permitting process. The $35,000 annual expenses relates to egg addling, permitting, annual moult counts, aerial counts and estuary restoration.
RELATED: Parksville culls 484 geese
Tardiff added that the City of Parksville has always taken the lead on goose management, with minimal financial support over the past three years coming from the Regional District of Nanaimo.
A harvest takes place each year in June with a B.C. Wildlife veterinarian on site. The geese are shot in the head with a bolt gun which kills them instantly.
Tardiff said the last three harvests have been done with First Nations groups, who use all of the goose meat.
Mayor Ed Mayne said since the goose management program has been put in place, the number of migratory geese in the Parksville area has significantly reduced.
"A 25 to 30 per cent decrease, if I'm not mistaken," Mayne said. "It's not something any of us want to do but it has to be done. The estuary will be totally destroyed if we don't do something."
Coun. Doug O'Brien said he's fully supportive of the city's goose management strategy.
"We are responsible for taking care of [the geese] before they destroy the estuary," he said. "It's an excellent program that the Guardians have put forward for us and their track record in past harvests has been very successful and they are making a huge difference already."
Coun. Adam Fras made a motion to direct staff to draft a letter to the RDN requesting they provide a third of the expenses for the goose management strategy.
karly.blats@pqbnews.com
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Slaying dragons: getting inside the minds of climate change skeptics

redpajama_set_name: RedPajamaCommonCrawl


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Homemade Hydroponics Setup in a Bucket
Cheapest Way to Grow Hydroponics
Homemade Hydroponic Nursery for Backyard Gardens
Cheap Way to Make a Hydroponic System
How Often Does a Hydroponics Tank Need to Be Cleaned?
How to Make a Hydroponic Nutrient Mixture
Hydroponics is any method of growing plants that doesn't use soil, and the method doesn't have to be fancy or hard to use. If you're one of the many people who have put off trying hydroponics because you fear its complexity, get ready to roll up your sleeves and dive into the plant-growing technique. Although commercial hydroponics setups can be extremely expensive and complicated, you can make a simple setup using nothing more than a plastic bucket and some gravel or perlite. No pumps or special nozzles are required.
Plants can grow in almost any kind of a bucket. If you want to grow something to eat, however, it's best to use a food-grade plastic bucket so that no harmful chemicals can leach into the system and end up on your plate. It's usually a good idea to avoid metal, too, because some types of metal may react to the hydroponic solution while other types just end up rusting. Either buy a bucket from a reliable source or ask a restaurant for a food bucket discard that you can clean and recycle as a hydroponic container.
No matter where or how they grow, all plants require the same basic nutrients. Those include elements they need in large amounts, such as oxygen, nitrogen, calcium, carbon and hydrogen. They need other nutrients in small amounts, including zinc, copper, molybdenum, cobalt and chlorine. Because hydroponic plants don't have access to nutrients in soil, it's up to you to ensure all their required nutrients are in the liquid nutrients you supply. Plants that don't receive the correct nutrients end up sickly and stunted, with yellow and dying leaves.
The simplest of all hydroponic systems is a bucket with some holes drilled around its sides to drain off excess water. Fill the bucket with perlite, clay pellets or sterilized pea gravel, and it's ready for planting. The water level should be high enough for a plant's roots to reach the nutrients but not so high that the plant can't get enough oxygen and ends up drowning. A young or newly moved plant needs to have water added to its bucket daily until its roots extend into the water at the bucket's bottom.
The bucket should be opaque to minimize algae growth. It's also best to keep the very top of the perlite or other medium dry to minimize algae growth. If algae gets started, it will rob the plant of nutrients and kill it. A bucket hydroponic system performs best outside because it is designed to overflow at some point. Setting the bucket in a pan or tray large enough to catch the leakage turns the simple system into a garden for all seasons; you can move the hydroponic plant indoors so it can benefit from controlled temperatures and artificial lighting.
University of New Hampshire Cooperative Extension: Hydroponic Vegetable Gardening
University of Arizona, Hydroponic Gardeners of Tucson: Six Systems That You Can Build
University of Florida IFAS Extension, Manatee County: Basic Hydroponic Systems and How They Work
North Carolina State University: A Gardener's Guide to Fertilizing Trees and Shrubs
Virginia Cooperative Extension: Home Hydroponics
DIY: Hydroponic Planters
Vegetable Gardens in Buckets
Recommendations on How to Start an Aquaponics System
How to Increase the Potassium in Aquaponics
Planting Vegetables in Pea Gravel
Gardening Hydroponics - Growing Plants Without Soil
Hydroponic Gardening Supplies for the Beginner
Common Problems With Bubbler Hydroponics
2 DIY: Hydroponic Planters
3 Vegetable Gardens in Buckets
4 Recommendations on How to Start an Aquaponics System


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Effects Energy Supplementation and Time on Use of Medusahead by Grazing Ewes and Their Lambs
Juan J. Montes- Sánchez
Helga Van Miegrot
Juan J. Villalba
Rangeland Ecology & Management
Medusahead is an annual weed that invades millions of acres in the western United States. This study explored the effect of energy supplementation on use of this unpalatable weed by ewes and their lambs. Thirty-six ewes with their lambs (2 − 3 mo old) were randomly assigned to 12 groups (3 ewes with their lambs per group), and half of the groups received 2.5 kg group d− 1 of an energy-based supplement (beet pulp − barley − Ca-propionate, 66:30:4; as-fed basis). After supplementation, all groups grazed plots with medusahead infestation for 15 d. Lambs were then weaned, kept in the same groups but without supplementation, and allowed to graze medusahead-infested plots for 3 d. Grazing events were recorded daily at 5-min intervals, and defoliation of medusahead tillers was measured in all plots. The proportion of grazing events recorded on medusahead and the proportion of defoliated medusahead tillers were not affected by supplementation in either ewes or lambs (P > 0.05). All ewe-lamb groups presented a greater proportion of medusahead use during the second half of the grazing period (P < 0.05). Nevertheless, the average proportion of events recorded for medusahead use was never greater than 7%, which was similar to the relative availability of medusahead in the community (i.e., 6%). Use of medusahead by ewes was correlated with that observed for their lambs (r = 0.83; P < 0.05), and weaned lambs showed a similar proportion of grazing events on medusahead to those observed before weaning (P > 0.05). These results suggest that mothers influence medusahead use by their offspring. They also suggest that despite the low palatability of medusahead, sheep will not avoid medusahead when grazing moderately infested rangeland. The diversity of the plant community likely contributed to this outcome, which might have also reduced the impact of the supplement on medusahead use by sheep.
J.J. Montes Sánchez, H.V. Miegrot, J.J. Villalba. 2017. Effects Energy Supplementation and Time on Use of Medusahead by Grazing Ewes and Their Lambs. Rangeland Ecology and Management. 70: 380-387
http://dx.doi.org/10.1016/j.rama.2016.11.005


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Home Jackery Zack Jackery Pen Holders – The Ultimate Portable Generator
Zack Jackery Pen Holders – The Ultimate Portable Generator
Zack Jackery Pen Holders – The Ultimate Review
Whether you are in the marketplace for a brand-new power supply or you simply require a little boost to your current one, the Jackery Explorer 1000 may be the most effective choice for you. Zack Jackery Pen Holders
This version has a great deal of attributes, including an unbelievable 1000W of continuous power and 2000W of rise power. It likewise has a 46.4 Ah lithium battery ability as well as two pure sine wave AC outlets.
In spite of its diminutive 22 pound weight, the Jackery Explorer 1000 loads a 1000W of juice. If you get on a budget plan, this is a terrific option. The Jackery gadget is additionally well fit for outdoor tasks. The very best part is it perseverance the majority of your smaller home appliances. You can also utilize it to bill your vehicle battery if you're so likely.
The Traveler 1000 comes with a 2,000 W rise inverter. This is more than enough to power the modern cooking area home appliance. Nonetheless, if you're looking for a real powerhouse, you'll have to step up to the Jackery juggernaut. The company has a number of models that fit the bill.
The Jackery 2000 and also the Jackery 1500 have a little a lot more pizzazz. They each have a 1045 watt-hour battery and are a tad on the heavier side. The very best component is, you can use both of them for optimum power. Zack Jackery Pen Holders
It's seldom that you obtain your hands on an Explorer 1000, so you could too make the most of your time while you go to it. The power station's slick orange coating is a welcome sight for the eyes. The business's website even boasts a complimentary 12-month warranty, which is more than most competitors. The item is likewise a solid ol' made splurge.
The Jackery device might be a little overkill for your average home, but you'll be happily stunned by its transportability. With the appropriate batteries as well as power adapters, you'll be able to appreciate the advantages of a complete giant, minus the mass. The Jackery product can power your small appliances while you're on the road or in the yard. The tiny, however mighty Jackery juggernaut can do it all.
Can charge up to 50 electronic cameras
Whether you're taking pictures of wildlife, outdoor camping, or simply enjoying the outdoors, the Jackery Explorer 1000 Portable Power Station is a great way to have power any place you go. This convenient generator provides lots of power for illumination, computers, and also various other electronic devices.
It's light, portable, as well as has a wonderful enhance appearance. The orange color scheme is expert looking. It also features an electronic display screen to help you see specifically just how much battery life you have left. It's a fantastic tool for digital photographers, but it's not a must-have for every single shoot.
The Jackery Explorer 1000 Portable Power plant deals with photovoltaic panels for additional charge. It has a solid feeling, is light-weight, as well as includes an inverter. Relying on the model you choose, you can charge up to 50 cameras.
This power plant has a big, lithium-ion battery. The battery is constructed to last and also store power for approximately 1002Wh of power. The lithium-ion battery is known for its high energy density and also lengthy life. It also powers the 12-volt power port as well as USB ports. It can be recharged by an AC wall outlet, vehicle battery charger, or by suitable solar panel. Zack Jackery Pen Holders
There are 4 temperature core detectors inside the battery, which is good for protection. It likewise has a battery administration system to ensure that the battery doesn't get too hot. It can be butted in as little as two hours by AC power or 2.5 to 7.5 hrs with solar Legend panels.
Unlike various other comparable products, the battery capacity of the Traveler is determined in Watt-hours. This is a far more precise measurement of how much power you have in your battery.
The Explorer has a small LCD display that shows the amount of power flowing into and also out of the battery. It's very easy to see how much power is fed back right into the billing ports, as well as the LCD show can be backlit.
While it's a terrific method to have power on the go, the Explorer 1000 does not offer a real "whole house" service. You can not connect in lights or appliances for longer time periods, and also it's a bit noisy.
Powered by a mighty lithium battery, Jackery Explorer 1000 is a power financial institution that is portable and also can power as much as eight laptop computer charges. The battery itself is rated to accept 2,000 W of peak power, as well as it shops electricity for up to 1002Wh. The battery can be recharged through a DC input port or Anderson Powerpole jack.
The Traveler 1000 has a great inverter, and also it has two USB-A ports, an AC port, and also a USB C port. It additionally features a built-in flashlight. Its display shows the portion of the battery and also the watts the tool is putting out. The best component is that it has a good cost controller.
It's also got a good LCD screen, and also the display reveals the battery's ability, as well as the input as well as result data. It's not very bright, though. The Jackery Explorer 1000 is a pretty cool little tool, however it could be much better.
It also has a good inverter as well as a battery administration system, as well as it utilizes Rate 1 LG battery cells. The lithium battery is recognized for its durability and also high power density. The lithium nickel manganese cobalt oxide battery can be found in many electric cars and trucks.
The one drawback of the Explorer 1000 is that it does not have true pass-through charging. It can power both sides of the battery at the same time, yet it can not do it completely. The Jackery company does offer a cushioned bring case for it. The battery and also charger can be billed making use of solar energy, however. The Jackery Power Outdoors website claims that they are the first firm to create a portable power station using lithium battery technology.
The Jackery firm was founded by a former elderly Apple battery engineer, Z. Sun, that has more than twenty years of experience in the field of lithium ion battery innovation. His items are tailored towards outside journeys, and also he has a proven record in the layout and manufacture of eco-friendly mobile power stations.
In short, the Jackery Traveler 1000 is a strong, affordable, all-in-one mobile power station that ought to suit the majority of people's needs. The battery is big, the battery charger is durable, as well as the handle is a wonderful touch. It has a few minor faults, but it's an excellent power bank for the cost. Zack Jackery Pen Holders
Whether you're searching for a dependable power source for your residence or to carry hand for outdoor camping, Jackery Explorer 1000 is a portable, eco-friendly service. With a rechargeable battery and photovoltaic panels, you can obtain a great charge, even in reduced sunlight. This is terrific for utilizing your cell phone and also Bluetooth speakers, along with your laptop computer.
Unlike a typical generator, Jackery Traveler 1000 makes use of a pure sine wave inverter to give a stable stream of power. This implies no noise or exhaust. It can likewise run most tools at the same time. You'll get a great stream of tidy power, and the batteries can last for days.
This generator is light-weight as well as portable, making it very easy to bring with you. It has a user friendly user interface as well as a cushioned carrying situation. You'll require a power brick as well as an a/c adapter to operate the device, but the charger will give you an eight-hour recharge.
During the day, the Traveler 1000 has adequate power to power a 50-watt laptop computer for about 20 hrs. The system can be charged via an automobile's accessory port, a house wall surface electrical outlet, or with photovoltaic panels. It has a multi-function LCD present, so you'll understand just how much power is left in the battery. It can manage power rises approximately 2000W. You can additionally charge your CPAP equipment with the unit.
The charging system on the Traveler 1000 is fast, allowing you to reenergize in 3 hours from almost empty. It's developed to run calmly, so you can use it in the wild, without triggering any disturbances.
The Traveler 1000 has a tough carry handle, but it can not be folded. This is a style flaw for anybody that prepares to pack it. It additionally makes it difficult to position products on the top. If you're searching for a cushioned case, think about other versions.
On the whole, the Jackery Explorer 1000 is an extremely long lasting as well as quiet power station, ideal for professional photographers on assignment or those that take pleasure in the outdoors. It's not a low-cost device, yet it does have a lot of functions. You can additionally buy a set of 100-watt photovoltaic panels, which will permit you to obtain more out of your source of power. Zack Jackery Pen Holders
Zack Jackery Pen Holders Zack Jackery Pen Holders
The mix that Jackery have actually put together here with solar energy and a versatile power plant is exceptional. The items are constructed well and also dependably do their work. Leading marks on that particular front, although I have some minor quibbles about the USB port types and also the variety of air conditioning outlets included.
There are absolutely less costly brands around, but there are likewise ones that are a lot more costly. Yet when you bring whatever together, such as develop top quality, convenience of use as well as aftercare support, Jackery is arguably the best in business. So all that's entrusted to make a decision is which size is best for you to go for.
A very early battery jacket the business developed for the Apple iPhone triggered the trademark name, Jackery. The business is based in Fremont, The golden state, with production in China, and also remains to have an Apple-like ambiance with its streamlined and smart product line.
All Jackery portable power stations consist of lithium batteries. Lithium-ion batteries are typically rated for 500 total fee cycles and/or 2 – 3 years.
The Jackery 290 is a Honda Authorities Certified Product by Jackery. It supplies outdoor enthusiasts with on-the-go power, providing a way to power up their favorite devices. This portable power plant has the ability to charge laptops, mobile phones, and tablets.
Jackery mentions numerous times that you can use the Traveler 1000 to power a portable fridge. Certain, however you can power an actual refrigerator, too.
The Jackery Explorer is a terrific selection for a mobile power plant, as it is geared up with a higher capability battery and a more effective AC inverter. This indicates you can conveniently utilize it to power your electric grill, coffee maker, hair clothes dryer, and also also your a/c unit while camping.
The very best portable power plant is the Jackery Solar Generator 1000. It has a 1000-watt outcome, which is enough power to charge your mobile phones, run a mini-fridge, or necessary medical equipment during a camping trip or power interruption.
The Jackery SolarSaga 80W Photovoltaic panel is just one of one of the most popular solar panels on the market. It's extremely reliable and also can generate as much as 80 watts of power. It's also extremely light-weight and also mobile, making it perfect for RVs. The SolarSaga 80W Solar Panel is really simple to establish as well as utilize.
It's a necessary home device– a mini-power station that flaunts best-in-class reenergizing rates, a big expandable ability, the capacity to be topped up making use of solar charging, and prolonged lifetimes. All that sets it aside from many mobile power stations on the marketplace.
You can charge one and have it prepared for residence usage. Or, take it with you when you're in your vehicle to make sure that you can keep your phone butted in instance of an emergency situation.


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Ridgewood man puts on elf hat during holidays
Mark Krulish
Staff Writer, @Mark_Krulish
When the white door opened on Ridgewood resident Jim Gibney's garage last week, it revealed a scene of sheer holiday magic: Inside were more than 200 donated gifts, wrapped and ribboned, in boxes and bags, ready to fulfill children's wishes.
The gifts were destined for children with special needs served by Youth Consultation Services, which works with more than 1,400 children in New Jersey.
And Gibney's role? Call him "Chief Elf." This is the fifth year the Ridgewood father and his wife, Cheryl, have participated in the YCS gift drive known as the Secret Santa initiative. Each year his involvement, and his elf squad, grows. He's enlisted scores of friends to donate gifts.
"From Thanksgiving to Christmas Eve, when I get a new child, he's the first call I make – he never says no," said Ruthie Harper, an executive director for YCS.
Monday was the moment when time, planning and countless hours of work to collect and organize these gifts paid off.
Gibney, Cheryl, and a few helpers happily loaded up the sleigh-driver's truck, belonging to, and driven by, friend Dennis Murphy, with toys bound for Youth Consultation Services in Hackensack. There, the items will be wrapped and distributed to YCS programs throughout New Jersey.
Gibney's involvement with YCS goes back to his first meeting with representatives at a charity dance event at In The Spotlight in Waldwick, in which his children danced. He signed on to be part of a mentor program at the Holley House in Hackensack, a YCS facility.
But when he caught wind of the gift drive initiative, he knew right away he wanted to be a part of it.
"[These kids are] no different from my three kids, they've just been thrown a curveball that's a little hard to hit and they just need support," said Gibney, speaking in his home last Friday.
And so a mission was born.
It all began with a simple email. Gibney reached out to 30 people asking for donations, and within several weeks, he had collected 50 gifts. That number has multiplied each year since. The response from donors has been enthusiastic, and Gibney now must field emails from elves asking when the drive begins.
The list of donors grew from a few friends in Ridgewood to people Gibney had not connected to in years – friends from elementary school and high school to whom he reached out on social media. He even enlisted his boss.
"They just trust in Jim, who trusts in us, that everything is going where it's supposed to go," offered the YCS's Harper.
As the gifts pour in, Gibney and his family find a place to temporarily store them in his home while he matches them to the proper child from a list provided by YCS. The gifts are tagged with the child's name and then placed in the garage. In the days before delivery, the Gibney home has toys filling the dining room and living room. For the first time this year, he had the use of a large, newly built garage, making storage much easier.
But no matter how much space Gibney may temporarily lose during the holiday season, there are no thoughts of reducing the number of gifts he tries to collect. In fact, he plans to bring in even more.
"It's so organic right now, it's so grass-roots," said Gibney. "Charity is local, that's what's so special about it. People get really excited about the child they're supporting. They don't know anything about the child, but they know this is their job."


Bak is really a terrific restaurant. Not only is the food delicious and beautifully presented, but the location is a treat in itself.
Grab a seat at the window for an amazing view over the IJ, especially at sunset. Restaurant Bak is located on the top floor of Het Veem. This striking structure was built a century ago as a warehouse for coffee, tea, tobacco and cocoa shipped from the Dutch colonies. Het Veem now houses offices for small businesses, artist studios and Het Veem Theater.
But about the food. Bak serves a set menu for lunch and dinner based on local, seasonal products. Choose from 3 or 5 courses at lunch and 5 or 7 courses at dinner. Your meal can be paired with wines, which of course we recommend. The wines are natural, and therefore are interesting and full of sparkling flavors.
We visited Bak for dinner at the height of summer and enjoyed a 5 course meal (plus wine and cheese) with gorgeous sunset views. We've also enjoyed lunch at Bak in the middle of winter and the food was even more delicious if that is possible.
At first glance the simple menu might seem unappealing. One of the dishes was described as "oatmeal, mussels, fennel and cornichons". To be honest, it sounded terrible to me. However, it was one of the most delicious dishes we tried! Creamy risotto-like oatmeal was topped with perfectly cooked mussels and sour cornichons. It still might sound strange, but it was surprisingly yummy! Other highlights of our summer meal included the dessert of strawberries and tomatoes with goat milk frozen yogurt and the amuse bouche of squid ink crackers topped with a tarragon mousse.
In the winter we enjoyed a dish of simple grilled onion with messenklever cheese which was surprisingly sweet and delicious. Our dessert dishes included a very tasty carrot and quark combination and a chocolate mousse with horseradish creme paired with a Goose Island Bourbon County Stout. Fantastic!
The wines paired perfectly with each dish. It was fun to taste the wine before the food was served, and then after taking a bite. The flavors complimented each other wonderfully. Perhaps the best phrase to describe dining at Bak would be "surprisingly delicious" as each dish is a special surprise with unusual combinations of ingredients.


Meridian Health Services is currently seeking an INTERN Masters Level Clinical Social Worker for our Childrens Services and Connxxions programs located in Indianapolis, Indiana. This position will be responsible for the provision of clinical services to children and adults in order to improve psychosocial functioning. Work hours can be flexible and correlate to student's school schedule and need. This internship will take place from January 2019 - June 2019.


I was having a stroll yesterday, enjoying the sight of the fine people of south London attempting to slide down the newly-laid snow on the slopes of Streatham Common. The contraptions used were many and varied, from a fellow strapped onto a snowboard, to children on the classic sledge you see on Christmas cards. Most amusing, however, was a couple of middle-aged women going down the Rookery with Sainsbury's carrier bags underneath their bottoms. Not the biggest surface on which to be sat, particularly when considering the scope of their back-sides, but they went down the slope at a decent clip nevertheless.
I'm a fairly loyal customer of Streatham Fruiterers, the greengrocers down near Streatham Hill Station, so I avoided the fruit and veg side of things. Ambling along, I found myself on the aisle with the breakfast cereals. Recently, I've moved towards Alpen as my cereal of choice. Seeking it out, I realised there was more work to be done in deciding which type of Alpen to buy.
All were £2.37, in same-size boxes. However, I noticed, with the alertness which rarely comes upon me in working hours, the Classic was 750g, while the other two were 560g.
I bridled at this. I am quite health-conscious, for two reasons: I want to live forever and enjoy being censorious about what other people eat. Therefore, I wanted the 'no added sugar' version. But, while I am health-conscious, I want good value. I envisaged buying the 'no added sugar' and finishing the box, knowing that if I had bought the Classic I would still have had another 190gs of the good stuff left. For once, my healthy lifestyle took second place to my parsimoniousness. I bought the Classic, yet felt like Sainsbury was making a mug of me.
Cantering about the store, I picked up some other essentials: pasta, bread, Bombay mix; at which point I realised I could have done with a basket. I am, if nothing else, efficient in my movements, and could not tolerate going back to the store entrance to pick one up. So I carried on, dropping the occasional item, picking it up, and dropping something else in the same motion. If Charlie Chaplin was there, doing his weekly shop, he would have thought it a bravura display of comic acting.
Having got my hands securely around all of my shopping, I came upon the herb shelf and realised I needed some dried oregano. I put my items on the floor, shoved the oregano in my jacket pocket, before going about the aforementioned picking up and dropping routine again.
Getting to the till, I unloaded the items on the conveyor belt, bar the oregano. I felt inside my pocket, and it was still there. While I paid for the vast majority of my items, the oregano stayed in my pocket.
Outside the store, I was so pleased with my work that I slid into the Pied Bull for a pint of Winter Warmer (£3.20). Ruminating about the matter, I saw clearly that Sainsbury could absorb the odd loss of oregano into its day-to-day running costs, with no harm to anyone. What's more, becoming more reflective at about the half-pint mark, I realised this festive generosity on the part of Sainsbury had secured my custom for the New Year, however sneaky some of its pricing might be.


text:
The Goa Mineral Development Corporation Bill, 2021
Government of Goa
The Goa Assembly passed the Goa Mineral Development Corporation Bill, 2021, which would enable the state government to start a corporation to carry out mining operations in an orderly, scientific and ecologically sustainable manner. The passing of the bill, assumes significance on account of the fact that fresh mining excavation in the state has been shut down since 2018 when the Supreme Court scrapped the renewal of 88 mining leases citing irregularities. According to the bill, the Corporation would be headed by the Chief Minister as the ex-officio Chairman and will have top officials including Secretaries in charge of Finance, Mines and Environment as members. The Corporation will also include a lawyer nominated by the state government, two experienced chartered accountants and a government nominated geologist.


text:
Hubert Seggewiß (* 11. Juni 1955 in Bocholt) ist ein deutscher Kardiologe. Er brachte  die Alkoholseptumablation (PTSMA, TASH, ASA) zur Serienreife, indem er zusammen mit seinem Kollegen Lothar Faber die Kontrolle des Verfahrens mit Ultraschall entwickelt hat.

Werdegang
Seggewiß ist als zweites von fünf Kindern in Bocholt geboren worden. Er machte 1974 Abitur und begann im Wintersemester 1974/1975 mit dem Medizinstudium in der Universität Köln und wechselte im Verlauf an die Universität Münster. Die Approbation erlangte er 1981. Zunächst arbeitete er an der Medizinischen Klinik Minden unter Seckfort, um Kardiologe zu werden. Er promovierte ende 1981 zum Thema "Echokardiographische Studien zur linksventrikulären Kontraktilität". 1983 wechselte er an das Gollwitzer-Meier-Institut und Herzzentrum NRW Bad Oeynhausen unter  Gleichmann. Nach Weiterbildung in der Medizinischen Klinik Bad Oeynhausen unter  Nissen und im Institut für Radiologie im Herzzentrum NRW Bad Oeynhausen unter  Weichert wechselte er 1987 wieder zurück an die Kardiologische Klinik des Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum unter  Gleichmann.  1987 wurde er Facharzt für Innere Medizin, 1988 Facharzt für Kardiologie. Im April 1994 habilitierte er zum Thema: "Revaskularisation der koronaren Mehrgefäßerkrankung mittels PTCA: Akutergebnisse und klinischer Verlauf in Abhängigkeit vom Revaskularisationgrad" Venia legendi Innere Medizin an der Ruhr-Universität Bochum.

Am 12. Januar 1996 führte er gemeinsam mit Ulrich Sigwart, Ulrich Gleichmann, Dieter Fassbender erfolgreich sechs PTSMAs im Herz- und Diabeteszentrum NRW durch. Zunächst wurde die Intervention durch probatorische Ballonokklusion des ersten Septalastes hämodynamisch gesteuert. Dies stellte sich als teils unpräzise heraus. Um diese Methode gezielter und sicherer zu machen, wurde im August 1996 die erste echokardiographisch gesteuerte PTSMA durchgeführt. Die Idee war, sicher zu wissen, welches Areal genau mit Alkohol abladiert werden wird, bevor dieser injiziert wird. Dies war der entscheidende Schritt der Methode, um ihn sicherer und das Ergebnis vorhersagbar zu machen. Die Echokardiographie gesteuerte Alkoholseptumablation ist auch in der aktuellen Leitlinie so empfohlen.

Im Jahre 2000 wurde er Chefarzt der Medizinischen Klinik 1 im Leopoldina Krankenhaus in Schweinfurt. Hier war er bis 2017 tätig und führte hier die meisten Alkoholseptumablationen an einem Zentrum in Europa durch.

Von 2018 bis 2020 war er am Klinikum Würzburg Mitte Standort Juliusspital als Consultant HOCM tätig.

Im April 2020 wechselte er an die Universitätsklinik Würzburg, um am Deutschen Zentrum für Herzinsuffizienz der Medizinischen Klinik 1 ein HCM-Zentrum zu gründen.

Mitgliedschaften
 Seit 17. Mai1982 Deutsche Gesellschaft für Innere Medizin
 Seit 1982 Mitglied der deutschen Sektion der IPPNW
 Seit 1. Januar 1984 Deutsche Gesellschaft für Internistische Intensivmedizin
 Seit 1. Januar 1985 Deutsche Gesellschaft für Kardiologie, Herz- und Kreislaufforschung und European Society of Cardiology - ESC, ESC Fellow
 2008 - 2012 Mitglied des Nucleus der ESC Working Group Myocardial and Pericardial Diseases
 2007 Ehrenmitglied der Hungarian Working Group Interventional Cardiology
 16. März 2012 Fourth Annual Razavi Lecture, Cleveland Clinic, USA
 Mai 2018 Ehrenmitglied der Ungarischen Gesellschaft für Kardiologie
 Seit 2000 Visiting Professor u. a. in Cleveland, New York, Toronto, Kansas, Seattle, London, Jerusalem, Helsinki, Kopenhagen, Stockholm, Warschau, Bukarest, Athen, Rom Madrid, Bern, Innsbruck, Graz, Szeged, Mumbai, Chandigarh, Tokio, Peking, Monastir, Bukarest, Doha, Berlin, München, Hamburg, Kiel, Marburg, Tübingen

Ehrenamtliche Tätigkeiten
 Juli 1997 Gründungsmitglied der Selbsthilfegruppe für Menschen mit Hypertropher obstruktiver Kardiomyopathie
 9. Juli 2016 Umwandlung der Selbsthilfegruppe in den HOCM e.V. (Gründungsmitglied und Beirat)
 Seit 2021 Ehrenmitglied des HOCM e.V.
 Leitlinienwatch e.V.
 MEZIS e.V.

Publikationen (Auswahl)

 U. Gleichmann, H. Seggewiss. Therapie der hypertrophen obstruktiven Kardiomyopathie [Therapy of hypertropic obstructive cardiomyopathy]. Dtsch Med Wochenschr. 1996 Nov 29;121(48):1485-6. German. doi:10.1055/s-2008-1043172. PMID 8983903.
 H. Seggewiss, U. Gleichmann, L. Faber. The management of hypertrophic cardiomyopathy. N Engl J Med. 1997 Jul 31;337(5):349-50. doi:10.1056/NEJM199707313370516. PMID 9235504.
 H. Seggewiss, U. Gleichmann, L. Faber, D. Fassbender, H. K. Schmidt, S. Strick. Percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy: acute results and 3-month follow-up in 25 patients. J Am Coll Cardiol. 1998 Feb;31(2):252-8. doi:10.1016/s0735-1097(97)00508-1. PMID 9462563.
 L. Faber, H. Seggewiss, D. Fassbender, N. Bogunovic, S. Strick, H. K. Schmidt, U. Gleichmann. Perkutane transluminale septale Myokardablation bei hypertroph-obstruktiver Kardiomyopathie: Akutergebnisse bei 66 Patienten unter Berücksichtigung der Myokard-Kontrastechokardiographie [Percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy: acute results in 66 patients with reference to myocardial contrast echocardiography]. Z Kardiol. 1998 Mar;87(3):191-201. German. doi:10.1007/s003920050171. PMID 9586154.
 L. Faber, H. Seggewiss, U. Gleichmann. Percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy: results with respect to intraprocedural myocardial contrast echocardiography. Circulation. 1998 Dec 1;98(22):2415-21. doi:10.1161/01.cir.98.22.2415. PMID 9832486.
 H. Seggewiss, L. Faber, U. Gleichmann. Percutaneous transluminal septal ablation in hypertrophic obstructive cardiomyopathy. Thorac Cardiovasc Surg. 1999 Apr;47(2):94-100. doi:10.1055/s-2007-1013118. PMID 10363608.
 L. Faber, H. Seggewiss, P. Ziemssen, U. Gleichmann. Intraprocedural myocardial contrast echocardiography as a routine procedure in percutaneous transluminal septal myocardial ablation: detection of threatening myocardial necrosis distant from the septal target area. Catheter Cardiovasc Interv. 1999 Aug;47(4):462-6. doi:10.1002/(SICI)1522-726X(199908)47:4<462::AID-CCD16>3.0.CO;2-9. PMID 10470478.
 H. Seggewiss Percutaneous alcohol ablation in HOCM. Catheter Cardiovasc Interv. 1999 Oct;48(2):241-2. doi:10.1002/(sici)1522-726x(199910)48:2<241b::aid-ccd33>3.0.co;2-4. PMID 10506796.
 L. Faber, A. Meissner, P. Ziemssen, H. Seggewiss Percutaneous transluminal septal myocardial ablation for hypertrophic obstructive cardiomyopathy: long term follow up of the first series of 25 patients. Heart. 2000 Mar;83(3):326-31. doi:10.1136/heart.83.3.326. PMID 10677415; PMCID: .
 H. Seggewiss Percutaneous transluminal septal myocardial ablation: a new treatment for hypertrophic obstructive cardiomyopathy. Eur Heart J. 2000 May;21(9):704-7. doi:10.1053/euhj.1999.2019. PMID 10739723.
 L. Faber, P. Ziemssen, H. Seggewiss Targeting percutaneous transluminal septal ablation for hypertrophic obstructive cardiomyopathy by intraprocedural echocardiographic monitoring. J Am Soc Echocardiogr. 2000 Dec;13(12):1074-9. doi:10.1067/mje.2000.108250. PMID 11119274.
 L. Faber, H. Seggewiss, D. Welge, D. Fassbender, P. Ziemssen, H. K. Schmidt, U. Gleichmann, D. Horstkotte. Vorhersage des Risikos permanenter atrioventrikulärer Uberleitungsstörungen nach perkutaner Septumablation bei Patienten mit hypertropher obstruktiver Kardiomyopathie [Predicting the risk of atrioventricular conduction lesions after percutaneous septal ablation for obstructive hypertrophic cardiomyopathy]. Z Kardiol. 2003 Jan;92(1):39-47. German. doi:10.1007/s00392-003-0878-7. PMID 12545300.
 L. Faber, H. Seggewiss, D. Welge, D. Fassbender, H. K. Schmidt, U. Gleichmann, D. Horstkotte. Echo-guided percutaneous septal ablation for symptomatic hypertrophic obstructive cardiomyopathy: 7 years of experience. Eur J Echocardiogr. 2004 Oct;5(5):347-55. doi:10.1016/j.euje.2004.01.001. PMID 15341870.
 F. Alfonso, L. P. Isla, H. Seggewiss Contrast echocardiography during alcohol septal ablation: friend or foe? Heart. 2005 Feb;91(2):e18. doi:10.1136/hrt.2004.050328. PMID 15657208; PMCID: .
 L. Faber, D. Welge, D. Fassbender, H. K. Schmidt, D. Horstkotte, H. Seggewiss Percutaneous septal ablation for symptomatic hypertrophic obstructive cardiomyopathy: managing the risk of procedure-related AV conduction disturbances. Int J Cardiol. 2007 Jul 10;119(2):163-7. doi:10.1016/j.ijcard.2006.07.179. Epub 2006 Oct 24. PMID 17067708.
 P. Charron, M. Arad, E. Arbustini, C. Basso, Z. Bilinska, P. Elliott, T. Helio, A. Keren, W. J. McKenna, L. Monserrat, S. Pankuweit, A. Perrot, C. Rapezzi, A. Ristic, H. Seggewiss, I. van Langen, L. Tavazzi; European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Genetic counselling and testing in cardiomyopathies: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur Heart J. 2010 Nov;31(22):2715-26. doi:10.1093/eurheartj/ehq271. Epub 2010 Sep 7. PMID 20823110.
 B. Pfeiffer, A. Rigopoulos, H. Seggewiß. Echokontrastmittelgesteuerte Alkoholablation bei hypertropher obstruktiver Kardiomyopathie mit neuem Echokontrastmittel [Myocardial contrast echocardiography guided alcohol septal ablation in hypertrophic obstructive cardiomyopathy with a new echocardiographic contrast agent]. Dtsch Med Wochenschr. 2012 Oct;137(41):2093-6. German. doi:10.1055/s-0032-1305229. Epub 2012 Oct 2. PMID 23033167.
 C. Rapezzi, E. Arbustini, A. L. Caforio, P. Charron, J. Gimeno-Blanes, T. Heliö, A. Linhart, J. Mogensen, Y. Pinto, A. Ristic, H. Seggewiss, G. Sinagra, L. Tavazzi, P. M. Elliott. Diagnostic work-up in cardiomyopathies: bridging the gap between clinical phenotypes and final diagnosis. A position statement from the ESC Working Group on Myocardial and Pericardial Diseases. Eur Heart J. 2013 May;34(19):1448-58. doi:10.1093/eurheartj/ehs397. Epub 2012 Dec 4. PMID 23211230.
 A. L. Caforio, S. Pankuweit, E. Arbustini, C. Basso, J. Gimeno-Blanes, S. B. Felix, M. Fu, T. Heliö, S. Heymans, R. Jahns, K. Klingel, A. Linhart, B. Maisch, W. McKenna, J. Mogensen, Y. M. Pinto, A. Ristic, H. P. Schultheiss, H. Seggewiss, L. Tavazzi, G. Thiene, A. Yilmaz, P. Charron, P. M. Elliott; European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur Heart J. 2013 Sep;34(33):2636-48, 2648a-2648d. doi:10.1093/eurheartj/eht210. Epub 2013 Jul 3. PMID 23824828.
 J. Veselka, M. K. Jensen, M. Liebregts, J. Januska, J. Krejci, T. Bartel, M. Dabrowski, P. R. Hansen, V. M. Almaas, H. Seggewiss, D. Horstkotte, P. Tomasov, R. Adlova, H. Bundgaard, R. Steggerda, J. Ten Berg, L. Faber. Long-term clinical outcome after alcohol septal ablation for obstructive hypertrophic cardiomyopathy: results from the Euro-ASA registry. Eur Heart J. 2016 May 14;37(19):1517-23. doi:10.1093/eurheartj/ehv693. Epub 2016 Jan 7. PMID 26746632.
 L. Faber, U. Gleichmann, D. Horstkotte, H. Seggewiss Kathetertherapie der hypertroph-obstruktiven Kardiomyopathie: Langzeitverlauf 1996–2016 [Catheter-Based Septal Ablation for Hypertrophic Obstructive Cardiomyopathy: Long-Term Follow-Up 1996–2016]. Dtsch Med Wochenschr. 2017 Feb;142(4):276-281. German. doi:10.1055/s-0042-121855. Epub 2017 Feb 24. PMID 28235228.
 R. A. Nishimura, H. Seggewiss, H. V. Schaff. Hypertrophic Obstructive Cardiomyopathy: Surgical Myectomy and Septal Ablation. Circ Res. 2017 Sep 15;121(7):771-783. doi:10.1161/CIRCRESAHA.116.309348. PMID 28912182.
 J. Veselka, L. Faber, M. K. Jensen, R. Cooper, J. Januska, J. Krejci, T. Bartel, M. Dabrowski, P. R. Hansen, V. M. Almaas, H. Seggewiss, D. Horstkotte, R. Adlova, H. Bundgaard, J. Ten Berg, M. Liebregts. Effect of Institutional Experience on Outcomes of Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy. Can J Cardiol. 2018 Jan;34(1):16-22. doi:10.1016/j.cjca.2017.10.020. PMID 29275877.
 H. Seggewiß, A. Koljaja-Batzner, K. Seggewiß, M. Meesmann. Synkope bei hypertropher (obstruktiver) Kardiomyopathie [Syncope in hypertrophic (obstructive) cardiomyopathy]. Herzschrittmacherther Elektrophysiol. 2018 Jun;29(2):178-182. German. doi:10.1007/s00399-018-0567-x. Epub 2018 May 14. PMID 29761339.
 M. Liebregts, L. Faber, M. K. Jensen, P. A. Vriesendorp, P. R. Hansen, H. Seggewiss, D. Horstkotte, R. Adlova, M. Michels, H. Bundgaard, J. M. Ten Berg, J. Veselka. Validation of the HCM Risk-SCD model in patients with hypertrophic cardiomyopathy following alcohol septal ablation. Europace. 2018 Sep 1;20(FI2):f198-f203. doi:10.1093/europace/eux251. PMID 29016960.
 A. Batzner, B. Pfeiffer, A. Neugebauer, D. Aicha, C. Blank, H. Seggewiss. Survival After Alcohol Septal Ablation in Patients With Hypertrophic Obstructive Cardiomyopathy. J Am Coll Cardiol. 2018 Dec 18;72(24):3087-3094. doi:10.1016/j.jacc.2018.09.064. PMID 30545446.
 A. Batzner, H. J. Schäfers, K. V. Borisov, H. Seggewiß. Hypertrophic Obstructive Cardiomyopathy. Dtsch Arztebl Int. 2019 Jan 25;116(4):47-53. doi:10.3238/arztebl.2019.0047. PMID 30855006; PMCID: .
 P. M. Seferović, M. Polovina, J. Bauersachs, M. Arad, T. B. Gal, L. H. Lund, S. B. Felix, E. Arbustini, A. L. P. Caforio, D. Farmakis, G. S. Filippatos, E. Gialafos, V. Kanjuh, G. Krljanac, G. Limongelli, A. Linhart, A. R. Lyon, R. Maksimović, D. Miličić, I. Milinković, M. Noutsias, A. Oto, Ö. Oto, S. U. Pavlović, M. F. Piepoli, Ristić AD, G. M. C. Rosano, H. Seggewiss, M. Ašanin, J. P. Seferović, F. Ruschitzka, J. Čelutkiene, T. Jaarsma, C. Mueller, B. Moura, L. Hill, M. Volterrani, Y. Lopatin, M. Metra, J. Backs, W. Mullens, O. Chioncel, R. A. de Boer, S. Anker, C. Rapezzi, A. J. S. Coats, C. Tschöpe. Heart failure in cardiomyopathies: a position paper from the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 2019 May;21(5):553-576. doi:10.1002/ejhf.1461. Epub 2019 Apr 16. PMID 30989768.
 H. Seggewiss, A. Batzner. Alcohol septal ablation in obstructive hypertrophic cardiomyopathy is a safe procedure in experienced hands. Rev Port Cardiol (Engl Ed). 2020 Jun;39(6):305-307. English, Portuguese. doi:10.1016/j.repc.2020.06.003. Epub 2020 Jun 27. PMID 32605835.
 A. Batzner, D. Aicha, B. Pfeiffer, A. Neugebauer, H. Seggewiss, Sex-related differences in symptomatic patients with hypertrophic obstructive cardiomyopathy - Time for a new definition? Int J Cardiol. 2021 Apr 1;328:117-121. doi:10.1016/j.ijcard.2020.12.039. Epub 2020 Dec 31. PMID 33359283.
 A. Batzner, D. Aicha, B. Pfeiffer, A. Neugebauer, H. Seggewiss. Age-related survival after alcohol septal ablation in hypertrophic obstructive cardiomyopathy. ESC Heart Fail. 2022 Feb;9(1):327-336. doi:10.1002/ehf2.13750. Epub 2021 Dec 13. PMID 34904378; PMCID: .
 R. Rudolph, H. Seggewiss, H. Seckfort. Osophagus-Ulcus durch Mexiletin [Esophageal ulcer caused by mexiletine]. Dtsch Med Wochenschr. 1983 Jul 1;108(26):1018-20. German. doi:10.1055/s-2008-1069687. PMID 6189689.

Deutscher
Geboren 1955
Mann
Kardiologe
Mediziner (20. Jahrhundert)
Mediziner (21. Jahrhundert)

redpajama_set_name: RedPajamaWikipedia


The author is in the Department of Biochemistry, Department of Molecular and Human Genetics, Howard Hughes Medical Institute, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
Cell cycle checkpoints are regulatory pathways that control the order and timing of cell cycle transitions and ensure that critical events such as DNA replication and chromosome segregation are completed with high fidelity. In addition, checkpoints respond to damage by arresting the cell cycle to provide time for repair and by inducing transcription of genes that facilitate repair. Checkpoint loss results in genomic instability and has been implicated in the evolution of normal cells into cancer cells. Recent advances have revealed signal transduction pathways that transmit checkpoint signals in response to DNA damage, replication blocks, and spindle damage. Checkpoint pathways have components shared among all eukaryotes, underscoring the conservation of cell cycle regulatory machinery.


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text:
Differential age-related loss of pigmented locus coeruleus neurons in suicides, alcoholics, and alcoholic suicides
Victoria Arango, Mark D. Underwood, Donna K. Pauler, Robert E. Kass, J. John Mann
We previously reported fewer locus coeruleus (LC) neurons in both suicide victims and alcoholics than among a group of nonpsychiatric controls. In the present paper we examine the rate of decline in the number of LC neurons with age, looking for possible differential rates among suicide victims, alcoholics, and controls. We also compare these groups with a group of alcoholics who died by suicide, and consider the effects of sex, race, and postmortem interval, LC neuron counts were obtained from a total of 32 subjects. In all groups, the number of neurons decreased with age, but by roughly age 40 the average LC count among the three suicide and/or alcoholic groups was lower than among controls. The rate of LC neuron loss was greater among suicides than among controls, but the rate of loss among alcoholics who were at least 30 years old was the same as that among the controls. Our group of alcoholic suicides had counts that were statistically indistinguishable from those of suicides. Differences among groups appear to be most pronounced in the middle third of the LC. Further studies are needed to determine the mechanisms of noradrenergic neuron loss and whether it is associated with an underlying major depression in suicide victims, or acquired after a period of excessive alcohol consumption.
Alcoholism: Clinical and Experimental Research
norepinephrine
Fingerprint Dive into the research topics of 'Differential age-related loss of pigmented locus coeruleus neurons in suicides, alcoholics, and alcoholic suicides'. Together they form a unique fingerprint.
Locus Coeruleus Medicine & Life Sciences
Alcoholics Medicine & Life Sciences
Suicide Medicine & Life Sciences
Neurons Chemical Compounds
Adrenergic Neurons Medicine & Life Sciences
Alcohols Chemical Compounds
Alcohol Drinking Medicine & Life Sciences
Depression Medicine & Life Sciences
Arango, V., Underwood, M. D., Pauler, D. K., Kass, R. E., & John Mann, J. (1996). Differential age-related loss of pigmented locus coeruleus neurons in suicides, alcoholics, and alcoholic suicides. Alcoholism: Clinical and Experimental Research, 20(7), 1141-1148. https://doi.org/10.1111/j.1530-0277.1996.tb01102.x
Differential age-related loss of pigmented locus coeruleus neurons in suicides, alcoholics, and alcoholic suicides. / Arango, Victoria; Underwood, Mark D.; Pauler, Donna K.; Kass, Robert E.; John Mann, J.
In: Alcoholism: Clinical and Experimental Research, Vol. 20, No. 7, 1996, p. 1141-1148.
Arango, V, Underwood, MD, Pauler, DK, Kass, RE & John Mann, J 1996, 'Differential age-related loss of pigmented locus coeruleus neurons in suicides, alcoholics, and alcoholic suicides', Alcoholism: Clinical and Experimental Research, vol. 20, no. 7, pp. 1141-1148. https://doi.org/10.1111/j.1530-0277.1996.tb01102.x
Arango V, Underwood MD, Pauler DK, Kass RE, John Mann J. Differential age-related loss of pigmented locus coeruleus neurons in suicides, alcoholics, and alcoholic suicides. Alcoholism: Clinical and Experimental Research. 1996;20(7):1141-1148. https://doi.org/10.1111/j.1530-0277.1996.tb01102.x
Arango, Victoria ; Underwood, Mark D. ; Pauler, Donna K. ; Kass, Robert E. ; John Mann, J. / Differential age-related loss of pigmented locus coeruleus neurons in suicides, alcoholics, and alcoholic suicides. In: Alcoholism: Clinical and Experimental Research. 1996 ; Vol. 20, No. 7. pp. 1141-1148.
@article{658355f4a2854c28a88e2e3af8b6c361,
title = "Differential age-related loss of pigmented locus coeruleus neurons in suicides, alcoholics, and alcoholic suicides",
abstract = "We previously reported fewer locus coeruleus (LC) neurons in both suicide victims and alcoholics than among a group of nonpsychiatric controls. In the present paper we examine the rate of decline in the number of LC neurons with age, looking for possible differential rates among suicide victims, alcoholics, and controls. We also compare these groups with a group of alcoholics who died by suicide, and consider the effects of sex, race, and postmortem interval, LC neuron counts were obtained from a total of 32 subjects. In all groups, the number of neurons decreased with age, but by roughly age 40 the average LC count among the three suicide and/or alcoholic groups was lower than among controls. The rate of LC neuron loss was greater among suicides than among controls, but the rate of loss among alcoholics who were at least 30 years old was the same as that among the controls. Our group of alcoholic suicides had counts that were statistically indistinguishable from those of suicides. Differences among groups appear to be most pronounced in the middle third of the LC. Further studies are needed to determine the mechanisms of noradrenergic neuron loss and whether it is associated with an underlying major depression in suicide victims, or acquired after a period of excessive alcohol consumption.",
keywords = "brainstem, human, norepinephrine, postmortem",
author = "Victoria Arango and Underwood, {Mark D.} and Pauler, {Donna K.} and Kass, {Robert E.} and {John Mann}, J.",
doi = "10.1111/j.1530-0277.1996.tb01102.x",
journal = "Alcoholism: Clinical and Experimental Research",
T1 - Differential age-related loss of pigmented locus coeruleus neurons in suicides, alcoholics, and alcoholic suicides
AU - Arango, Victoria
AU - Underwood, Mark D.
AU - Pauler, Donna K.
AU - Kass, Robert E.
AU - John Mann, J.
N2 - We previously reported fewer locus coeruleus (LC) neurons in both suicide victims and alcoholics than among a group of nonpsychiatric controls. In the present paper we examine the rate of decline in the number of LC neurons with age, looking for possible differential rates among suicide victims, alcoholics, and controls. We also compare these groups with a group of alcoholics who died by suicide, and consider the effects of sex, race, and postmortem interval, LC neuron counts were obtained from a total of 32 subjects. In all groups, the number of neurons decreased with age, but by roughly age 40 the average LC count among the three suicide and/or alcoholic groups was lower than among controls. The rate of LC neuron loss was greater among suicides than among controls, but the rate of loss among alcoholics who were at least 30 years old was the same as that among the controls. Our group of alcoholic suicides had counts that were statistically indistinguishable from those of suicides. Differences among groups appear to be most pronounced in the middle third of the LC. Further studies are needed to determine the mechanisms of noradrenergic neuron loss and whether it is associated with an underlying major depression in suicide victims, or acquired after a period of excessive alcohol consumption.
AB - We previously reported fewer locus coeruleus (LC) neurons in both suicide victims and alcoholics than among a group of nonpsychiatric controls. In the present paper we examine the rate of decline in the number of LC neurons with age, looking for possible differential rates among suicide victims, alcoholics, and controls. We also compare these groups with a group of alcoholics who died by suicide, and consider the effects of sex, race, and postmortem interval, LC neuron counts were obtained from a total of 32 subjects. In all groups, the number of neurons decreased with age, but by roughly age 40 the average LC count among the three suicide and/or alcoholic groups was lower than among controls. The rate of LC neuron loss was greater among suicides than among controls, but the rate of loss among alcoholics who were at least 30 years old was the same as that among the controls. Our group of alcoholic suicides had counts that were statistically indistinguishable from those of suicides. Differences among groups appear to be most pronounced in the middle third of the LC. Further studies are needed to determine the mechanisms of noradrenergic neuron loss and whether it is associated with an underlying major depression in suicide victims, or acquired after a period of excessive alcohol consumption.
KW - brainstem
KW - human
KW - norepinephrine
KW - postmortem
U2 - 10.1111/j.1530-0277.1996.tb01102.x
DO - 10.1111/j.1530-0277.1996.tb01102.x
JO - Alcoholism: Clinical and Experimental Research
JF - Alcoholism: Clinical and Experimental Research


With experience and backgrounds ranging from Teaching to corporate business it's fair to say the ISIC NZ team brings a wealth of experience and always a lot of ideas to the table.
We're at our best with a coffee or two in our hands, attending some face to face meetings and testing out our cardholder benefits. So drop us a line if you want to talk cards, partnerships, discounts and anything in between.
Your favourite ISIC discount in NZ: No question about it...River Rats water rafting and our Skydive NZ benefits. Great value and full of adventure. What's not to love!
Jodie can most commonly be found...in sunny Queensland or jet-setting around Asia Pacific. Drop Jodie an email to chat about collaboration opportunities and global partnerships! Although based in the sunshine state, Jodie is often in NZ managing creative collaborations and partnerships with aligned businesses.
Your favourite ISIC discount: 25% off Auckland Harbour Bridge Bungy Jump!
Nadine is your go-to for all partnership opportunities. She spends most of her time meeting organisations discussing partnership opportunities or representing ISIC at events in New Zealand.
Contact Nadine if you are keen to offer ISIC cards via your organisation or partner with us in any way.
Your favourite ISIC discount in NZ: 10% off ZORB!
Matt can most be found...in our high rise office in Melbourne's Southbank setting up new processes and systems for our partners and providing them with day to day support. In addition to this Matt manages all in house printing processes. Contact Matt for any system based questions or printing enquiries.
Your favourite ISIC discount in NZ: You can't get much better than up to 15% off car hire with Europcar. It's a dream for anyone wanting to explore NZ!
Lou can most commonly be found...in our Melbourne Office planning our campaigns and digital activity as well as on skype to our overseas counterparts. Reach out to Louisa for any Marketing opportunities (collaborations, giveaways, campaigns, content, advertising) across Australia, New Zealand, Thailand & Singapore.
Your favourite ISIC discount in NZ: It has to be 20% off all rides with OGO Rotorua.
James can most commonly be found...enjoying the view of the city from our Melbourne office while ensuring all day to day management of online card orders runs smoothly. James is also the face behind our content creation and blog. Contact James for any questions you have about your online card order and any queries about our blog, emails or Facebook pages.
Your favourite ISIC discount: My favourite discount in NZ is 20% off any pizza at Pizza Pomodoro!
Jenna can most commonly be found...in our Melbourne office liaising with benefit and sales partners across Australia, New Zealand & Singapore or out and about checking out new opportunities and discount partners to add to our program. Reach out to Jenna if you want to join our benefit program.


Okay, two things I resent: being categorized and being dismissed. It's like when you have a slightly non-standard issue with, say, the cable company. You contact them and in a calm, well-mannered tone present a thorough yet concise summary of your case. They immediately tag you as a troublemaker and send you into an inescapable phone-tree pit with actual troublemakers. "But… but I had a legitimate question!" Too bad for you.
Well said, it could almost apply to many levels of government.Must be time for local citizens to take actions.


We are thrilled to introduce our blog's debut wedding, a rustic, very Adirondack celebration along the banks of the Boquet River in Elizabethtown, NY. This July 2011 wedding had so much country charm, from Adirondack pack baskets filled with flowers to handmade quilts to dozens of candle-filled antique Ball jars. If you look closely, you might recognize a couple of these photos from the debut issue of Adirondack Weddings magazine.
Photo credits: Rows 1 and 3, canning jar in row 5, Jecca D Photography. All others, Adirondack Weddings staff photos.
Ryan & Chelsea had told guests to expect a simple celebration with a band and some beer, so we were delighted to find so many fantastic details at every turn—vintage crates, bales of hay, handmade quilts, hand-sewn blue-checkered tablecloths, crocks filled with cocktails, and two kinds of wine made by the groom's mother. Guests enjoyed a light buffet meal and danced to classic songs played by a live band while children ran around with sparklers. After the final song of the night ("American Pie"), fireworks lit the sky as guests lounged in Adirondack chairs around a bonfire. Congratulations to Ryan & Chelsea on a fantastic celebration and best wishes for an everlasting marriage!
Stay tuned for Part II, in which we will unveil what is possibly the coolest guestbook ever.
Planning an Adirondack Wedding. Who do I need to call to find out how to have my wedding here on the Boquet River. Basically what venue is it?
My fiancee and I have a camp on the boquet river in Willsboro, NY but I FELL IN LOVE WITH THE PICTURES OF THIS LOCATION!!!! Where is it?!?!?!?!
Hi ladies – This wedding took place on private property, not a wedding venue. Sorry not to be more helpful, but we're so glad you enjoyed the photos!
Jessica – will do! It was such a fun gathering.
The details are amazing! Those Adirondack pack baskets are gorgeous, as are the bell jars and candles. I want a beautiful, casual wedding just like this.
Thanks, Sarah! This couple did a fantastic job bringing country chic elements together.


The paper is titled "Signal, noise and resolution in linear and nonlinear structured‐illumination microscopy". Mats Gustafsson sadly passed away in 2011, after the original version of the manuscript had been submitted. A few years later, one of Mats's colleagues, Rainer Heintzmann, graciously volunteered to help Eugene Ingerman and and Rich London revive the paper and finally get it published, 11 years after the original submission.
We are very grateful to Rainer for enabling this important paper to be published. It stands as a testament to Mats Gustafsson's enormous contribution to microscope, more of which can be read at www.nature.com/articles/nmeth.1612.


text:
Revenge Season 4 Premiere, Spoilers And Latest News: A New Villain Is Introduced To The Hamptons As Victoria Finds A Way To Turn Her Greatest Setback Into A Dangerous Advantage In The Upcoming Season
By John Kevin Muu Sep 11, 2014 05:02 PM EDT
We have the latest for you on the premiere, spoilers and latest news of Revenge season 4. Revenge season 3 came to a sad end leaving its audience dread and weary from the terrifying action they had seen in the ended season. It has not been a long wait per say but we can now confidently say that we are nearing the season premiere of the much awaited fourth season. The audience of Revenge series have been keeping tabs on the latest from Revenge and recently we had the premiere photos released online. The trailer has also been released and everything is looking really exciting as the trailer seems to suggest that the season premiere will be on September 28th this year on ABC. The series has introduced a new villain to the Hamptons for the fourth season and her name is Emily Thorne.
Madeleine Stowe's Character explains as a narrator in the trailer, "My name is Victoria Grayson and I have a story to tell. Over the past three years my family was destroyed, the love of my life was murdered, my freedom was taken away. When everything you love has been stolen from you someone has to pay. Emily Thorne, I'm coming for you."
This is clearly a show that we are going to see an Emily-Victoria showdown happening in this season as that statement clearly marks the two rivals in the plot. But let us not get ahead of ourselves. However, we can get ready for a season with a whole lot of action. The synopsis of the first episode titled 'Renaissance' shows that Emily will host 'her most surprising party ever'. The synopsis reads, "Victoria will find a way to turn her greatest setback into a dangerous advantage." What is this setback that she is going to turn into a dangerous advantage? Many would ask. It is well known at least by those who follow the series that Victoria is currently under lock down in mental asylum thanks to Emily but leave it to Conrad's wife to find a way to manipulate the disconsolate situation.
We also discovered from E! News that another character will be saying goodbye when an important figure also tied to Conrad dies mysteriously. Stay tuned for the premiere on 28th September on ABC.
Tags : the Revenge latest the Revenge updates the Revenge news the Revenge latest news the Revenge latest updates latest on the Revenge news on the Revenge updates on the Revenge latest news on the Revenge latest updates on the Revenge latest: the Revenge news: the Revenge updates: the Revenge latest news: the Revenge latest updates: the Revenge the Revenge news updates news updates on the Revenge news updates: the Revenge the Revenge season 4 coming soon the Revenge season 4 premiere to be out soon revenge season 4 premiere revenge season 4 spoilers revenge season 4 latest news
Previous Celebrity Apprentice 2014: Joan Rivers Highlights the Next 2 Episodes of Celebrity Apprentice
Next JJ Weeks "The Sound of Freedom" EP Review
Revenge Season 4 Release Date Set for September 10, 'Renaissance' is Revenge Season 4 Premiere Episode, Plus Other Revenge Season 4 Spoilers!
Revenge Season 4 Spoilers: Executive Producer Sunil Nayar Spills the Beans on David's Scoop, Victoria Drama and Conrad's Fate
Revenge Season 4 Spoilers and Update: Who Will Die, Victoria's Revenge and Other Exciting New Revelations
Revenge Season 4 Spoilers, Air Date, Trailer, Spoilers And Latest Updates: Jack Takes Up A New Role As A Cop And This Could Be Another Roadblock For His Love Connection With Emily
Revenge Season 4 Premiere, Trailer, Spoilers, Grand Finale Recap And Latest Updates: Emily Stops At Nothing In Her Search For Victoria, Who's At The Mercy Of Her Own Sinister Secret


¿Qué es My Austin Quinceañera?
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text:
Dennis Gerald Littlejohn (October 4, 1954), is a former Major League Baseball player who played catcher from  to . He would play for the San Francisco Giants. Littlejohn attended the University of Southern California.

External links

1954 births
Major League Baseball catchers
Baseball players from California
San Francisco Giants players
Living people
USC Trojans baseball players
Alaska Goldpanners of Fairbanks players
Denver Bears players
Fresno Giants players
Phoenix Giants players
Waterbury Giants players


text:
American Military Forces (10)
World War II - Veterans (30)
Weapons and Aircraft (25)
Causes of World War II (19)
WWII Wartime Diplomacy (10)
Historical Overview of World War II (17)
World War II Maps (3)
World War II - European Theater (265)
World War II - Pacific Theater (115)
Japanese Surrender (2)
Battle of Leyte Gulf (2)
The Atomic Bombings (9)
Battle of Kwajalein (1)
Battle of Saipan (1)
Battle of Guam (1)
Battle of Peleliu (1)
Pearl Harbor (46)
USS Arizona (1)
News Reports (2)
Pearl Harbor (overview) (13)
"The Lost Evidence: Pearl Harbor" (THC series) (5)
"Battlefield: Pearl Harbor" (series) 1-5 (5)
"Battle field: Pearl Harbor" (series) 6-10 (5)
Aleutian Islands (2)
Battle of Guadalcanal (2)
Battle of the Java Sea (1)
Battle of Okinawa (8)
Battle of Marshall Islands (1)
Battle of Midway (23)
Battle of Iwo Jima (14)
North African Campaign (4)
World War II Air Fights (8)
World War II Amphibious Assaults (3)
World War II Life in the USA (19)
Women in World War II (6)
Native Americans in World War II (2)
"The Philadelphia Experiment" (series) (5)
The End of WWII (20)
World War II (WatchMojo Series) (8)
This Day in History-December 7, 1941-Pearl Harbor
From TeacherTube
A summary of the Pearl Harbor raid. Includes actual news footage of events occurring that day. Ends with questions about the day for students to answer or discuss. Would make a good warm-up activity for the beginning of class.It is a combination newsreels, slides, and text.
Ages: 10 - 18 License: Undetermined Owner: unspecified Found by angeland


Register your Tongan .to domain name with us today!
Register your Tongan domain name with 0dns.org today and take advantage of savings for multi-year registrations. read about the pricing, registration requirements, and registration timeframe for .to below.


text:
ENESFR
Human rights-based approaches
Culturally sensitive approaches
Results Based Management approach
South-South and Triangular Cooperation
Internal Audit and Investigation
Strategic Plan 2018 - 2021
UNFPA in the UN system
Programme Expenses
Data Quality and Usability
Policies & Procedures Manual
Communication Policies
Facilities and Administrative Services Policies
Finance and Budget Policies
Issuance Policies
Information and Communications Technology Policies
Resource Mobilization Policies
Safety and Security Policies
Technical Assistance Policies
Oversight and Internal Audit and Investigation Policies
Corporate Environmental Responsibility in UNFPA
Sustainable Procurement in UNFPA
Protection from Sexual Exploitation, Sexual Abuse and Sexual Harassment
Private Sector Spotlight
TransformU - University Network
Women's Health in the Workplace
Generation Equality Forum: Action Coalition on Bodily Autonomy and SRHR
We Decide: Including and empowering persons with disabilities
Resources and Funding
Audit and Investigation
Goodwill Ambassadors and Patrons
UN Population Award
Obstetric fistula
Adolescent pregnancy
Comprehensive sexuality education
Youth leadership & participation
Human rights & gender equality
Engaging men & boys
Gender-biased sex selection
Demographic dividend
Cox's Bazar, Bangladesh
Tigray, Ethiopia
Campaigns & Interactive
Midwives offer care, dignity and a lifeline for Haiti's mothers
"We are rewarded when we hear the newborn's cry and see the mother's smile," said midwife Résia Pierre Pierre (right). © UNFPA Haiti
PORT-AU-PRINCE, Haiti – Elizabeth was exhausted after hours of contractions at the Petite Place Cazeau clinic, in Port-au-Prince, Haiti. Finally, with gentle guidance from the midwife, she gave one last push. Stifled cries filled the delivery room.
The nurse presented a baby girl to the new mother. Through half-closed eyes, Elizabeth watched as her daughter was cleaned and weighed.
Afterward, in a spacious recovery room, she cradled her baby – whom she had named Lisa.
"It was a bit difficult, but I felt safe," she told UNFPA, explaining that she had not expected such sophisticated care.
A newborn is warmed under a lamp at a UNFPA-supported maternity centre in Port-au-Prince, Haiti. © Jared Chambers
"Everyone was so nice to me. Even though I had no idea what all those machines were for, I was not really afraid when they took my baby away… They explained it was to measure her. They brought her back to me really fast. She looks like a little doll, don't you think?"
'Smile clinics' meet critical needs
The facility is one of four so-called 'smile clinics' in Haiti. These UNFPA-supported centres offer a full range of services, including antenatal care, family planning counselling, and basic emergency obstetric and newborn care – all free of charge.
The clinics also offer hands-on training to new midwives.
The director of the Petite Place Cazeau clinic, Dr. Harold Scutt, insists that midwives take the reins on all obstetric and newborn care. It is recognition of the critical role midwives can – and must – play in saving women's lives.
"Midwifery training contributes directly to reducing maternal mortality," he said. "For example, they learn to detect the first signs of eclampsia, which is key since pre-eclampsia and eclampsia remain the leading causes of maternal death during childbirth."
These services are essential in Haiti, which has the highest maternal death rate in the Western hemisphere.
Haitian women have a 1 in 90 chance of dying from pregnancy-related causes in their lifetimes, according to the 2015 Trends in Maternal Mortality report. By contrast, a woman in Canada has a 1 in 8,800 chance of dying from such causes.
The country's vulnerability to natural disasters has not helped matters. Catastrophes like last year's Hurricane Matthew reduce women's access to health facilities.
Midwives celebrate their graduation from the national midwifery school. Quettly Chevalier, the director of the school, sits in the middle of the graduates. © UNFPA Haiti
And even when women make it to clinics, they often find the staff shorthanded. According to Dr. Reynold Grand Pierre, director of family health at the health ministry, "over a third of government-trained midwives left the country between 2010 and 2012."
Increasing the number of midwives
UNFPA is working with the government to increase the supply of well-trained midwives.
In downtown Port-au-Prince, near Cité Soleil, the Isaiah Jeanty Hospital is temporarily hosting the National Midwifery School in earthquake-resistant containers.
The school's original building was severely damaged by the 2010 earthquake. It reopened in 2013 with support from UNFPA and the health ministry. UNFPA also provides assistance with transportation, equipment and the curriculum.
"Did you know that in 2013, we only had 211 midwives throughout the country?" asked Quettly Chevalier, the institute's director. The World Health Organization has estimated at least 2,200 midwives are needed to significantly lower maternal deaths.
The school is steadily closing this gap. From 2000 to 2017, it trained 349 midwives, and more than 80 midwifery students are currently enrolled in the programme.
Working with love
Friday, 5 May, is the International Day of the Midwife, a day to celebrate the work of midwives around the world and to highlight the need for more health workers trained in these life-saving skills.
Midwifery-led care is considered to be highly cost-effective. With the right training and support, midwives could avert roughly two thirds of all maternal and newborn deaths, experts estimate. They also learn to provide sensitive and dignified care that improves women's trust in the health system.
Ms. Pierre became interested in midwifery while providing social service in a maternity facility. She went on to train under an experienced UNFPA midwife. © UNFPA Haiti
That was true for Gertrude Duval, who was resting in the bed next to Elizabeth. Ms. Duval had just given birth to her second child.
"It is so different from the hospital in which I had my first child," she said.
Her improved experience was thanks to professionals like midwife Résia Pierre Pierre.
"When helping a woman giving birth, every move must be precise, fast and accurate. We are responsible for two lives," Ms. Pierre explained.
"Midwifery is a very noble profession," she said. But "it's often underestimated, even ignored."
Still, she encourages others to join her, and counsels them to follow the example set by countless midwives around the world and "do their work with love."
–Vario Serant
In this refugee camp, midwives have delivered over 14,000 babies with zero…
In Pakistan's remote areas, midwives ensure care beyond safe birth
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For some reason, there is this perception that all bloggers who are doing this full time must be making bank, or that you are a lazy millennial who doesn't want a "real job"… This also seems to be true of social media influencers such as Youtubers and Instagramers. So, perhaps I get asked the question " So, how much money do you make?", more than most, but my response is probably not appealing to most people- "I make enough".
To be honest, I never quite know how to answer this question because the answer is multifaceted. The amount I make every month changes- sometimes drastically-as do my expenses. Another thing, is that I earn about half my income now from Youtube and Instagram…Because I've diversified not only my income, but the way I drive traffic to my blog.
So, I'll try to break down how much I personally make, in a bit, but first let's explore how I and others make money in the first place so you can understand why this question is so loaded and so difficult to answer as a whole.
To really understand the potential earning for a blogger, you first have to understand how bloggers make money.
These platforms allow you to places ads on your site and you get paid per click. Now, the average conversion rate is said to be about 3% across the web. Meaning that 3% of people who visit a website will click on an advertisement and make the website some money.
The amount you get paid per click can vary from a penny to over $5.00, or in super rare cases $10.00 .. I always like to do a conservative number and say that the average click is probably between 25 cents and $1.00. So, taking that lower number of 25 cents, let's see how much you could make with various visitors.
Now, obviously this is a VERY rough calculation because every individual website will have a different conversion rate (percent of people that click on ads) and different amounts they make per click.
For instance, I had a site a couple years ago that made over $3000 a month on ads with only 3000 visitors. I attribute that to the fact that it was a diet site so the ads paid more because there's a lot of money in the diet industry. There were also lots of relevant ads to be displayed on the site. A site about knitting is probably not going to make anywhere near that though… In fact they would probably make something more along the lines of our example.
Once again, the amount of money blogs make with this is very subjective to the type of blog and the products they're promoting.
Someone who uses Amazon to promote a variety of products will only make 4% commission a sale. Whereas someone who uses a luxury vacation rental affiliate platform might make 30% a sale. Like I said above, I like to be conservative with my math when I'm calculating what I (or others) could make with a product. So, I assume 3% will click on the link and 3% will buy it. This is REALLY low for most industry standards, because most of the time if someone is clicking, they're interested in the product. However, it's better to be pleasantly surprised in my opinion than let down and not able to pay your bills!
So let's say you have a style site and you're going to promote a pair of shoes using Amazon. If that pair of shoes cost $40, then you'll make $1.60 per sale with the 4% commission. So, If 3% of your visitors click to go look at the shoes and then 3% buy it, you'll need approximately 1000 visitors to your website to make one sale- which will make you an income of $1.60.
On the other hand, if you have a luxury travel blog and you promote a luxury vacation get away that costs $5,000 and you make 30% commission, you'll make $1,500 a sale. So for that same 1,000 visitors we talked about with the Amazon example, you could make $1,500.
Is it starting to become clear why it's so difficult to answer the question of how much bloggers make?!
The product you sell depend on your site. There are Eproducts and physical products which have different costs to make and sell and various profits. Even a small site can make a lot of money selling products if they know what their audience wants.
For instance, the diet site I owned a couple years ago was on vegan diets, so I sold two different vegan diet EBooks. Those Ebooks were $29.99 and $39.99. I also bundled them and sold them together for $59.99. About 50% of my traffic clicked into my Ebook section and 30% of them bought one of the programs… With 4000 visitors a month I sold 600 Ebooks on average a month. Obviously, the total I made varied depending on the particular books sold, but you get the idea. Even with a small number of visitors, I made some good money. But, I KNEW what they wanted because I made the site very niche and specifically for them.
A lifestyle blog, such as this one, is a bit harder to define and make products for which means there isn't as much potential for large profit without large numbers of visitors… so once again, the amount you can make with a product depends on a number of factors!
Along with products, some bloggers sell services which can be in person- such as a fashion styling appointment, or online- such as a website consultation. Typically, services are charged per hour and bloggers typically charge at least $100 an hour.
Typically, we think of sponsorships as being something only Influencers get, but bloggers can get sponsors as well for reviews, product promotions etc.
If you're unaware of what a sponsorship is, it's when a business pays you to feature their product or services in a post. The amount you can get paid for a sponsorship varies immensely from blog to blog. The average blog post is probably worth at least a few hundred per sponsored post, but the reality is that it depends on the brand that wants to work with your site and what your site is worth.
It's impossible to say what a site might make with sponsored posts, but it could be six figures a year in the right industry!
This article isn't about ways to monetize your blog, it's about how much bloggers make.
So, I don't want to go into too much detail here, but there are TONS of creative ways that bloggers also make money besides the normal.
For instance, speaking engagements, are highly profitable. Pay-per click affiliate marketing is becoming more popular, as is Livestreaming on platforms like YouNow, and making content for loyal fans using Patreon. You even have people offering paid email newsletters and membership platforms as additional ways to make money on their sites.
If you have good content that makes people keep coming back and other websites link to you.
As a broad rule of thumb, the amount you can expect to make is proportional to the time and energy you put into your blog and how targeted the choices you make are. I made my first $1000 the month I started my blog, but that's not normal. Most people go at least 3 months before they even see a penny and at least a year if not longer before they make a full time income.
But, as you've seen above, there are many ways to monetize a blog and make a good income, even with a small number of visitors a month- if you have a plan, know your audience, and hustle the opportunities are there! With that being said, most bloggers who start blogging as a hobby, never turn their blogs into a business- or it takes them years to do so.
I told you in the beginning of the blog that I would talk about how much I make as a blogger. Here's the deal, I honestly can't say I make a certain amount every month and that there's a normal for me.
I've had months where I've made tens of thousands, and months where I've been in the hole. I started online with niche sites (essentially blogs focused on one tiny topic). I used a lot of various ways to monetize those sites- which means when I had traffic I made a good income. I also catered to very specific communities. But I did one thing extremely wrong. I had only one traffic source- Google. So, basically I relied on my sites ranking on Google where people could find. That was my only source of traffic. For the most part I stayed in the top five positions in Google, but, sometimes, Google would knock my site down in rankings and I wouldn't get the traffic I normally had. In those months I would make way less money, or even sometimes be in the whole $20 or $50 at the end of the month because I still had the expenses that I had when I was making $3,000 or $10,000 or $30,000…. Ultimately I made a decent profit throughout the year, but I can't say there was an amount I made that was normal, nor could I say "I make a $100,000" or "$40,000", it was just too subjective to a bazillion elements.
This year however, I'm focusing on building out this particular site and building out multiple channels of traffic so I can project an amount that's reasonable to live on and not have to worry so much about how Google feels about my site. I'm projecting with a lot of hard work to make a minimum of $40,000 this year with this site, and equal amounts with Youtube and Instagram.
Ultimately what you can make as a blogger depends on so many things, with a good plan and a good topic, making a living as a blogger is definitely possible.


text:
Q: Como salvar campos no banco de dados com letras maiúscula com Nodejs, TypeORM e Postgres? Como posso salvar alguns campos de um objeto com letras maiúsculas? Eu sei converter strings com o ToUpperCase, mas no exemplo abaixo eu não sei como fazer. Alguém poderia me ajudar?
 const createProduct = productsRepository.create({
    follow_up,
    name,
    product,
    size,
    name_color,
    code_color,
    status,
    code_karsten,
    price,
    image,
    isActive,
});

await productsRepository.save(createProduct);

return createProduct;

No caso acima, preciso que apenas o campo product seja convertido em maiúsculo.

A: Uma maneira de resolver o problema é utilizando a JavaScript Object Notation (JSON) para a criação de objetos JavaScript. A maneira que utilizou é a que eu vou chamar de maneira abreviada (A notação de objeto literal), que foi introduzida no es5.
Desta forma, segue um exemplo:
 const name = 'nome';
 const product = 'produto';

 //notação maneira abreviada de criação de objetos
 const tudo = { name, product }

 //utilizando a notação literal...
 const tudo2 = {name, product: product.toUpperCase() };
 // Object { name: "nome", product: "PRODUTO" }

Para saber mais consulte a documentação
Para o seu caso específico a solução seria o seguinte:
const createProduct = productsRepository.create({
    follow_up,
    name,
    product: product.toUpperCase(),
    size,
    name_color,
    code_color,
    status,
    code_karsten,
    price,
    image,
    isActive,
});

A: fiz da seguinte forma:
const nameToUpperCase = name.toString().toUpperCase();

const createProduct = productsRepository.create({
  follow_up,
  name: nameToUpperCase,
  product,
  size,
  name_color,
  code_color,
  status,
  code_karsten,
  price,
  image,
  isActive,
});

await productsRepository.save(createProduct);

return createProduct;

Obrigado a todos pela a dica!!!

A: Assim também funciona:
const createProduct = productsRepository.create({
  follow_up,
  name: name.toUpperCase(),
  product,
  size,
  name_color,
  code_color,
  status,
  code_karsten,
  price,
  image,
  isActive,
});

await productsRepository.save(createProduct);

return createProduct;

redpajama_set_name: RedPajamaStackExchange


text:
Сухопутные войска Марокко или Королевская марокканская армия (, ) — один из видов войск (сил) Вооружённых сил Марокко, созданы в 1956 году.

Состав
2 военных округа: Северный (оборона страны, штаб в Рабат) и Южный (Западная Сахара, штаб в Агадир).

 7 бригад (3 механизированные, 2 воздушно-десантные, 1 бронетанковая, 1 лёгкая охранная),
 8 механизированных и мотопехотных полков (в каждом 2—3 механизированных батальона),
 63 отдельных батальона (11 бронетанковых, 35 пехотных, 3 на верблюдах, 1 горнопехотный, 4 коммандос, 2 парашютно-десантных, 7 инженерных), 11 отдельных артиллерийских дивизионов и 1 дивизион ПВО.

В королевской гвардии — 1 батальон и 2 кавалерийских эскадрона.

Вооружение и военная техника

Согласно данным IISS The Military Balance на 2020 год Сухопутные войска Марокко имели в своем распоряжении следующую технику:

Ссылки

 Вооруженные силы Марокко 13.06.2002

Вооружённые силы Марокко