The best way to introduce a large group to the principles of Sun Tzu is with a keynote. The Sun Tzu and the Art of Business keynote overviews the Six Principles that Mark developed based on, Sun Tzu and the Art of Business. Mark uses The Art of War, military illustrations and insightful business examples.
Mark has presented to thousands of people in the U.S., Europe and Asia, including 3M, IBM, Royal Bank of Scotland, Tennessee Valley Authority, Society of Competitive Intelligence Professionals, and the US Air Force Command and Staff College.
This is an excellent way to shift a team's thinking so they can compete and win.
An excellent way for your team to gain a deep understanding of Mark's Six Principles is with a workshop. With half-day to full-day training sessions for up to 30 employees, these sessions provide unparalleled insight into Sun Tzu's principles as applied to business. The workshop overviews the six principles, then explores each in depth. In addition to insightful business and military examples, Mark relies on fun and challenging exercises and discussion.
Gain new ways to think and compete, along with a process to follow to build a strategy based on Sun Tzu's principles. Mark's workshop can be customized to meet the specific needs of your team.
Based on her book, Sun Tzu for Women, Becky's keynotes and workshops educate and inspire women in corporations, business groups, government agencies and nonprofits to take full advantage of their careers. Sharing relevant and current research, Becky brings a fresh presentation against an intriguing backdrop of timeless strategy.
This dynamic and eye-opening presentation highlights pitfalls and success attributes within the inspiring and empowering context of The Art of War. Women come away with new insight into their competitive advantages, and how to use them to catapult their careers.
This is a deep and personalized dive into common pitfalls and attributes, helping every woman to take control of her career with a detailed self assessment and meaningful time for small group and open discussion.
Does your organization need a fresh strategic approach so your leadership can help guide you to seize the advantage?
Battlefields change. Competitive landscapes change. Markets shift. Companies that adapt and execute based on proven and sound strategy win.
Sun Tzu Strategies' Art of War Executive Workshops are an intense, customized two day, strategy-building session for up to 10 executives/managers. The Workshop is an in-depth introduction to the Six Principles as applied to business, and assists you in developing a strategy built on those principles. At the end of the workshop you and your leadership team will leave invigorated, excited and, most importantly, hold a draft strategy or set of strategic options on which to build.
The Art of War was written to enable a smaller force to overtake larger, better equipped adversaries. This keynote is designed to enable small businesses or businesses in highly competitive spaces to do just that.
This keynote is based on The Art of War for Small Business, the first book to apply Sun Tzu's wisdom to the small business arena. Each keynote is customized to the business and/or industry of the audience so that the most impactful and applicable of Sun Tzu's principles are highlighted.
Big companies may deploy overwhelming forces, but small companies can outsmart, outmaneuver, and outstrategize larger adversaries to capture crucial sectors, serve unmet needs, and emerge victorious.
Our prices reflect industry standard rates and standard travel fees. Our keynotes and workshops are of the greatest impact when we're able to customize them to your challenges, opportunities and market conditions.
Contact us for a specific price for your event, conference, executive retreat or other need.


text:
BC announces regional COVID-19 restrictions for eastern Fraser Valley
Vincent Plana
Sep 28 2021, 8:16 pm
Provincial Health Officer Dr. Bonnie Henry (Gov BC/Flickr)
New regional COVID-19 restrictions have been announced for the eastern Fraser Valley.
The announcement was made on Tuesday afternoon by Provincial Health Officer Dr. Bonnie Henry and Health Minister Adrian Dix. Henry says that in the area, there has been an increase in COVID-19 cases in schools, as well as in the wider community.
"As indicated, we have seen a notable rise in cases in schools, in the broader community in the Eastern Fraser Valley," Henry said. "As a result, there is a new regional public health order that will be in place in Fraser East local health area that will come into effect today."
The orders will be similar to the regional approaches taken in BC's Interior and the North, which address decreased rates of immunization and increased COVID-19 transmission.
The communities of Hope, Chilliwack, Abbotsford, Mission, and Aggazis-Harrison will be affected.
Private indoor gatherings will be limited to five additional people or one additional household. Private outdoor gatherings will be limited to 10 people unless all participants are fully vaccinated.
Organized indoor events such as weddings or conferences will be limited to 10 people indoors or 50 people outdoors unless all participants are fully vaccinated.
Ticketed events such as movies, plays, and ticketed sporting events can also continue, as well as indoor sports, exercise and fitness. All participants will need to be fully vaccinated.
Similarly, unless all people playing are fully vaccinated, outdoor sports will also be limited to 50 people.
Vincent Plana+ FOLLOW
+ Coronavirus

redpajama_set_name: RedPajamaCommonCrawl


I know we're not supposed to get sappy on a road trip, but Banff just brings out the girl in me. Ten years ago, when I left Banff (and the girl), my housemates took me out on my last night for fondue at the Grizzly House. It's a Banff institution, once it was a rocky mountain themed disco. Anyway, coming back here (I avoided it on all my previous returns to Banff with various girls) got me a little misty eyed. Eh. Anyway, this is one of those Banff "must-do's". The food is just good, not great, but you can't beat the atmostphere. And table-to-table calling.


text:
Home biography Antawn Jamison
Antawn Jamison Biography
Facts of Antawn Jamison
1976 , July-12
Quick Timeline of Antawn Jamison
1976 Born in Shreveport, Louisiana, United Sates
2003 Married with Rucker Jamison
2016 Net worth is $60 million
1998 Joined Golden State Warriors
2004 Joined Washington Wizards
2003 Joined Dallas Mavericks
2010 Joined Cleveland Cavaliers
2012 Joined Los Angeles Lakers
2013 Joined Los Angeles Clippers
2014 Retired from professional basketball career
Detail Timeline of Antawn Jamison
June 12 , 1976
Born in Shreveport, Louisiana, United Sates
Antawn Jamison is a former American professional basketball player who was born in Shreveport, Louisiana, United Sates. He played for teams: Golden State Warriors, Dallas Mavericks, Washington Wizards, Cleveland Cavaliers, Los Angeles Lakers and Los Angeles Clippers.
Married with Rucker Jamison
Antawn Jamison got married to Rucker Jamison in 2003. The couple has four children together named as Katherine Elizabeth Jamison, Antawn Jamison Jr., Alexis Jamison and Rucker Jamison. The couple was happy and together but they couldn't continue their marriage and got divorced.
Net worth is $60 million
Antawn Jamison has earned a good sum from his professional basketball career. He played with many teams and has been successful in his career. In 2016, his net worth was estimated to be around $60 million with an average earning of $15.08 million annually.
Joined Golden State Warriors
Antawn Jamison made his professional basketball debut from Golden State Warriors in the year 1998. He spent hid first 5 years in NBA with Golden State Warriors, where he scored his career-high 51 points on two occasions, against Lakers and Seattle.
Joined Washington Wizards
Antawn Jamison left Dallas Mavericks and joined Washington Wizards in the year 2004. While with Wizard he was named in NBA ALL-Star team for the first time in his career. He played for about 6 years with the Washington Wizard.
Joined Dallas Mavericks
Antawn Jamison left Golden State Warriors and joined Dallas Mavericks in 2003. He experienced his first winning season 2003-04 with Dallas Maverick as Mavericks finished with 52-30 to make it to playoffs. During his game with Mavericks, he was named as NBA's Sixth Man of the Year.
Joined Cleveland Cavaliers
Jamison was bought by Cleveland Cavaliers in 2010. While playing with Cleveland he scored 19 points in his second game against Orlando Magic. He played for about 2 years with the club and his last season with the Cleveland 2011-12, he finished with average 17.2 points and 6.3 rebounds.
July 25 , 2012
Joined Los Angeles Lakers
Jamison left Cleveland Cavaliers in 2012 and he was signed by Los Angeles Lakers on July 25, 2012. He played his first game for Lakers against the Los Angeles Clippers. He scored his first point aginst for the team Lakers against Denver Nuggets.
Joined Los Angeles Clippers
Jamison was signed by the Los Angeles Clippers on August 28, 2013. He scored his first point with the club against Boston Celtics where he scored a 3-pointer. He played for a year with the club and then he was traded to Cenk Akyol.
Retired from professional basketball career
After joining Cenk Akyol on February 20, 2014. He played there some months and he announced his retirement from professional basketball in October 2014. After his retirement, he became a broadcaster for Time Warner Cable SportsNet where he was a TV analyst.
Antawn Jamison was married to Rucker Jamison in 2003. The couple is blessed with four children named: Katherine Elizabeth Jamison, Antawn Jamison Jr., Alexis Jamison and Rucker Jamison. The couple was together for many years but they couldn't continue their marriage for long and got divorced. The couple didn't reveal the reason behind their divorce. Currently, Antwan is dating his secret girlfriend, they were spotted together in the Beverly Hills by their fans.
Antawn Jamison is also involved in many social campaign programs. He has commenced a campaign named "A Better Tomorrow", from which he has the plan to give better future to the underprivileged.
Antawn Jamison has earned a good sum from his professional career and his recent net worth was estimated to be around $60 million.


text:
Italy's citrus industry wastes an estimated half of the 500,000 tons of citrus it produces each year. Two designers want to turn some of that into thread to make clothing.
Photograph courtesy Orange Fiber
In Fashion, Oranges May Be the New Black
Italian designers are eagerly spinning wasted citrus into silky threads that could one day make our garments shine.
ByCatherine Zuckerman
Picture a Hollywood awards show in the not-too-distant future. Celebrities dot the red carpet, while reporters chase them down to fawn over their couture. But instead of asking the classic, "Who are you wearing?" the question posed instead is, "What are you wearing?"
If Sicilian designer Adriana Santanocito has her way, the answer might be, "I'm wearing citrus."
Welcome to the small-but-growing world of sustainable fashion. (See Turning Food Waste Into a Fashion Statement.) In the same way that consumers have become more conscious about where their food comes from and how its production impacts the environment, some innovative fashion designers are thinking about how to create eye-catching garments and accessories that are both high-end and low-carbon footprint.
Case in point: Santanocito and her business partner, Enrica Arena. At their Catania-based startup, Orange Fiber, they're turning citrus waste into satiny fabric and silky, colorful yarn destined to be stitched into dresses, scarves, and more.
These dried orange peels may make their way into your wardrobe someday.
Santanocito formed the idea in 2011 when she was working on her thesis in fashion design at the Afol Moda Fashion Institute of Milan. Driven by the desire to make a positive contribution to her Sicilian homeland, Santanocito found herself researching citrus—one of the region's most iconic, yet wasted, foods.
"Because of imports and other issues, a lot of Sicilian oranges are not harvested," says Arena, and estimates published in the journal Agriculture suggest that every year in Italy the citrus juicing industry uses roughly 500,000 tons of fruit, more than half of which ends up going to waste.
Realizing an opportunity to put all those scraps to good use while simultaneously pulling together her final project, Santanocito developed a process—which is now patented—for extracting cellulose from citrus peels, leaves, and seeds and then spinning that cellulose into an innovative, eco-friendly textile the women call Orange Fiber.
"It's very similar to silk and viscose," says Arena, "with a soft, light feel, similar to twill." The company has also produced a lace-like fabric blended with silk, and another blend that Arena describes as "more similar to satin." "These are just examples of the infinite possibilities that our yarn can develop," she says.
Clothing and accessories made from Orange Fiber aren't commercially available yet, but according to Arena, the company is currently working with a well-known fashion brand and hopes to have some products on the market by the end of this year.
"We continue to dream big," she says. "Our wish is to replicate our model in every country where citrus juice is produced."
Catherine Zuckerman is a staff writer for National Geographic magazine. Her proudest moment to date? Watching her one-year-old daughter devour her homemade bolognese. Find her on Twitter.


Both the righteous and the wicked—even the animals!—go to the same place at death. All physical creatures are composed of dust and return to dust again. These scriptures make it abundantly clear that no one goes to either heaven or hell at death, and further, no one who is dead has the capacity to feel joy or pain.


1.1 What is separation ?
Vorticity is an intrinsic local ingredient of the flow dynamics.
How is reversed vorticity introduced in the flow ?
the wall responsible for vorticity transport (diffusion) in the flow.
Nothing has been said so far about the flow Reynolds number !
It is zero at S.
Where does the adverse pressure gradient come from ?
solid boundary in a layer <<d.
flow from low speed region toward the ML.
How strong the adverse pressure gradient should be ?


September 1, 2016 — John M. Buol Jr.
This book is an examination of Second Amendment rights in the United States and presents many facts and statistics that refute the anti-gun movement. Author Robert Jordan provides a definitive and in-depth examination of the anti-gun movement's claims and tactics, and the facts and statistics that completely refute them. Jordan emphasizes he is not a politician, political operative, or media expert with a bully pulpit, just a regular American citizen with a desire for exhaustive research that is tired of seeing Constitutional rights under attack.
These Are My Guns begins with an overview of the the issues and some of the root causes and continues with a historical breakdown of events and writings by people influential before, during, and after the Constitution was framed and written and goes up through modern court rulings on Constitutional law concerning the Second Amendment. This is followed by Cold Hard Numbers, a chapter detailing statistical analysis of data as published by various government agencies. Following this overview, Jordan continues with Anti-Gun Tactics and News Media Complicity, giving examples of how policy and reporting differs with ASAAs (Anti-Second Amendment Activists) from collected data. The wraps up with a point-by-point rebuttal of an Institute Of Medicine report, the author's conclusion, a comprehensive set of tables concerning injury rates as reported by government agencies and an extensive bibliography and reference section.
Originally from Flint, Michigan, Jordan is an architect as well as chief photographer of Spectre Imaging, specializing in architectural and outdoor photography. This is his first book and he was driven to write it in defense of Second Amendment rights that he sees as eroding along with other basic rights that are supposed to form the backbone of the United States.


Not only do our operations deal with birds daily, but they also impact you.
Why is SaskPower concerned about bird populations and nesting locations?
Birds and other wildlife cause about 4,000 power outages yearly.
Because of this we've created a plan to lower our interactions with birds. We want to know what bird species live near our facilities. That's why we're supporting the creation of the Bird Studies Canada Saskatchewan Breeding Bird Atlas.
What is the Breeding Bird Atlas? How will SaskPower use this research?
Some species of birds, such as grassland song birds, have been declining in population. Data from this work will help us plan better when working in nesting habitat. It'll also help us avoid sensitive areas where we can.
Research for the Atlas began in 2017. Atlas' like this repeat every 20 years to document population changes. This is the first time Saskatchewan is creating a Breeding Bird Atlas. This research will wrap up in 2021.
When and how can I take part in surveying for birds?
So far, 165 people have logged 88,000 records and found 260 species in the province! Bird surveying happens between late May to mid-August, with a focus on June.
Volunteers collect bird counts and observations for the Atlas. All the data's used to make a collection of maps for each bird type in the province.
How was one employee involved with this initiative?
Brett Quiring, a SaskPower employee, is using his passion for birding to help with the project. To date, he's put in over 200 hours of his own time into surveying for the Atlas. He's also the regional co-ordinator for the southeast part of the province.
The Atlas identified the areas around the power plants as priority areas. This was a great chance to discover species at risk. While he was birding at Poplar River, Brett spotted a Least Tern. This is an endangered species not expected in Canada. This was a great find!
How has SaskPower managed risks caused by birds?
There are situations where you should or shouldn't help. Unsure what to do? Call the provincial wildlife hotline at 306-242-7177 or visit their website here.


text:
G-Day Wrapup
Thursday April 11, 2013
A perfect day for football brought out a record G-Day crowd, and they got a show. Even with the shuffling of lineups and the unfamiliar reserves filling out the rosters, G-Day for once turned into a somewhat compelling game. The black team (largely the retooled starting defense) made things difficult for the red team, and they were able to make a couple of late plays to pull off a mild 23-17 upset of the red team. I admit that I wanted to see Murray come out for red's final possession as he did in the first half and try to win the game with a 2-minute drive.
I wanted a chance to watch the broadcast before writing this up and finally got a chance to do it. Enough has been written by now that we'll hit just a couple of positions and finish with some other notes.
Give me Mitchell, Bennett, Conley, and Rumph as the first four receivers, and I feel about as comfortable with that position as I do with Marshall and Gurley at tailback. Rumph needn't have a Cordarrelle Patterson type of impact – he'll be a tough matchup for anyone as a 3rd/4th receiver. The combination of size, decent speed, and the ability to fight for a few extra yards after contact give Georgia a nice option even if he might not yet be polished enough to be a starter.
The receivers were a big question that lingered into the season as we wondered whether King and Brown could handle larger roles. As we learned that they could, the position became a strength, and the offense prospered. Replacing those seniors was the question entering this season, and we seem to have the answer much sooner this year.
With a nervous eye on Bennett's recovery (on track) and Mitchell's meniscus surgery, we also saw last season that the depth has to go beyond just the first four. I'm fairly comfortable with the next group – Wooten and McGowan are seniors who are more than familiar with the offense, and Murray seems to have confidence going to McGowan. Justin Scott-Wesley continues to develop and had some nice catches on Saturday; I doubt the coaches will hesitate to call on him during the season. Tibbs had a rough start – a bad drop followed by a personal foul out of frustration. We heard enough about Tibbs in practice last season to want to see more, but the depth is solid enough for now that he won't be thrown into the fire yet.
It wasn't so much that a defensive lineman was dominant. It was that several players look ready to contribute. That was the main concern – after losing Jenkins, Geathers, Jones, and Washington, there had to be more than one player emerge to help Garrison Smith. That's what happened at both tackle and end. Thornton and Mayes were active inside, and Mayes looks like he will be the second JUCO (after Rumph) to see a fair amount of playing time. Ray Drew seems to have found a home at defensive end, and every time we looked it seemed as if he was chasing quarterbacks in the backfield. We were interested to see how Taylor's size would affect his move to defensive end, but he thrived there with two sacks and seven tackles in the G-Day game. Taylor has earned the attention of his coaches, and it will be tough to keep him off the field.
One thing you couldn't get a handle on thanks to the format of G-Day is how Coach Wilson will approach the rotation for the line. Garner was known for his doghouse and a very conservative approach to substituting. Georgia still isn't especially deep along the defensive line, but its strength might be in a pool of at least six capable guys (depending on Toby Johnson's recovery from knee surgery). We're at least encouraged that Wilson, like Friend on the other side of the line, will have some options and choices at his disposal.
Bobo wasn't especially down on the offensive line, but it was hardly a dominant performance. This is the classic spring game conundrum, but it's hard to imagine noticing the play of so many defensive linemen without some help from the OL.
Bobo put some of the defense's nine sacks on quarterbacks holding onto the ball too long. I can't remember ever seeing so many quarterback scrambles – the game's leading rusher at halftime was Hutson Mason.
Speaking of Mason, the scrimmage did little to change the outlook at quarterback. Mason was shaky in the first half (and the interception he threw was just a bad decision), but at least he settled in. Mason eventually brought the black team back for the win and ended up completing 16 of 27 attempts. It's a bit of a toss-up after that though. Ramsey is headed for a redshirt. Going just by this game, Welch seems to be the better option at #3. LeMay had a couple of passes (including the interception) that should have been caught, but those were his passing highlights.
Chris Conley has talked about adding some moves to go along with his speed, and he got the chance to show off a little shiftiness on a nice reception down the south sideline.
The order behind Gurley and Marshall is something that will have to be revisited closer to the season once the freshmen get here. It's G-Day tradition to overstate a performance by a reserve tailback, but Karempelis at least saw the field in 2011. J.J. Green didn't look lost in his debut, and that's more than you can expect from an early enrollee.
A lot of eyes were glued to Matthews and Harvey-Clemons in the secondary, but Quincy Mauger quietly had a nice day with eight tackles. Mauger also made a very wise decision: he could have had the hit of the day on an unsuspecting Rumph but spared his teammate. Reggie Wilkerson was put in a tough spot as an early enrollee going up against the first team offense, but he looked surprisingly confident and capable.
As always, the most important thing about G-Day is getting through it with no serious injuries, and that looks to have been the case. Atkins sprained his knee, but that won't be a long-term problem. Mitchell and Bennett should be ready to go by early summer, and we should have a fairly full and healthy roster ready to put in work over the summer.
One more thing…it was great to see a nice turnout for Rennie Curran's book signing. The book had sold out by the time we dropped by, and they were adding to a waiting list. I'm looking forward to reading and reviewing it. You can find out more information and pick up a copy of the book by visiting Curran's web site.
Comments Off on G-Day Wrapup
"It seems like every week this year, (Wooten's) gotten better and better."
Joe Cox


The second issue of Andrew McCluskey's RekameMag has been released. Contributions from other Game Maker users (and Rebecca Clare Smith) are alongside those written by Andrew.
Thankfully after a pain-inducing front cover in the launch issue the abstract design included in this issue has been toned down.
Dan Fornace discusses approaches to multiplayer gaming, Andrew looks at the various forms of Internet media which we have seen used to convey information about Game Maker and Rebecca takes a look at Game Maker from the outside and reaches the same conclusions as many of us seasoned community members.
There is also a look at the various forums Game Maker users socialise in, an interview with yours truly, 4 game reviews by Andrew and @Alex@, another interesting puzzle and some interesting Game Maker related album art.
A little short, but it was very well put together.


It's been revealed that the Queen's private estate has been holding millions of pounds worth of investments off-shore.
Information from a document leaked by Appleby, a Bermuda-based law firm specialising in offshore accounts, shows that the Duchy of Lancaster (the private estate of the British monarch) has invested money in a Cayman islands off-shore portofolio.
The 'Paradise Papers' refers to the leak of 13.4million files by a collection of media who investigated the issue.
The documents show that in 2005, the Queen's estate invested significant amounts of money (around £10 million) into businesses including off-license chain Threshers, and retailer BrightHouse, which sells furniture, appliances and technology on payment plans.
The Duchy has stated that the Queen and her estate received no financial tax benefit by storing the funds overseas, but the findings are still likely to encourage people to want more transparency about how the royals spend money.
The new information has also caused tension due to controversy surrounding the company BrightHouse. The company have been accused of aggressive selling tactics on vulnerable people, including those with mental health issues and learning disabilities in the past.
However, the Duchy has now stated that there was just £3,208 held in BrightHouse, and they were not aware that the investment was going directly to them.
Critics have also pointed out that Threshers went bust in 2009, still owing over £17.5 million in tax. And so the fact that the Queen holds these investments off-shore, is likely to spark questions.
Richard Palmer, royal correspondent for Daily Express, has suggested that many royal commentators believe the revelation is "not ideal" for the monarchy's reputation.
However, a spokesperson for the Duchy of Lancaster has said, "We operate a number of investments and a few of these are with overseas funds. All of our investments are fully audited and legitimate.


Providing wireless service in not just a few buildings, but on the general grounds of campus can greatly improve the quality of life for students studying, learning, and connecting with each other.
While your need your campus wired, it's best to have it wireless. Serving many hundreds of connections with high-speed access, Slice can make sure people students, faculty and staff can connect wherever they are.


text:
Imports System.Reflection
Imports System.Runtime.CompilerServices
Imports System.Runtime.InteropServices

' General Information about an assembly is controlled through the following
' set of attributes. Change these attribute values to modify the information
' associated with an assembly.

' Review the values of the assembly attributes

<Assembly: AssemblyTitle("BasicAnalyzers")>
<Assembly: AssemblyProduct("BasicAnalyzers")>

<Assembly: ComVisible(False)>

' Version information for an assembly consists of the following four values:
'
'      Major Version
'      Minor Version
'      Build Number
'      Revision
'
' You can specify all the values or you can default the Build and Revision Numbers
' by using the '*' as shown below:

redpajama_set_name: RedPajamaGithub


text:
The Beauty of a Running Club
By jasonpatmore 0
Running Club in Liverpool Street.
One of the positives to emerge from retiring from professional ballet was the opportunity it allowed me to involve myself in new sports.
My targets for my first year was to get involved in running and cycling. Long term I would like to get involved in playing football again and taking my first steps into the boxing ring. But we can save that for another blog.
My cycling journey started with the acquisition of my first ever road bike and my first session in the Olympic Velodrome. However I have been unsuccessful in my attempts to find a club that fits in my schedule. However I have been much more successful in my search for a running club.
I wanted to join a running club for several reasons. I find running alone can quickly become monotonous and I find it all too easy to cancel planned sessions. By committing to a club and training with other people I have eliminated this possibility. This is especially important coming into the winter months. click here for my newsletter on training in Autumn. Secondly I wanted to learn from other people with more expertise than me. I have completed a couple of 10k's but I am a relative novice when it comes to running training and competing.
The club I attend, put on free by Runners Need, has delivered on all of the above. The sessions are varied and have helped me to develop physically and technically in my running. But maybe what I was expecting was the social element. The feeling of a community and everybody willing to help and encourage their 'teammates' has been a massive plus point. So much so that through their encouragement I have decided to enter some events come the 2016 season. I am sure, with all their support, experience and tips I will reach new heights in my running training and races.
So watch this space for all the details on my races in the 2016 and how I get on. For anybody looking for a new sport or challenge surrounding yourself with like minded individuals is the perfect start. I am happy to be on my running journey and to be well under way in attacking the goals I set myself when I retired.
I cant wait to find the same experience with a cycling club in due course and set myself even more targets. If anybody knows of a great cycling club in south west London then drop me a message on my twitter @mattino22
author: jasonpatmore
I am a Personal Trainer and coach based in Liverpool Street.
JDP Shop
Contact Us 18 July
07:00AM 20:00PM
Contact us at anytime!


text:
Two Bills Drive
Buffalo Bills News and Discussion
Archives for March 30, 2019
Losing for Levy: How throwing game led to Buffalo Bills hiring HOF coach
'"There were a lot of older players who didn't care for Coach Bullough at all," Wolford told Moran. "And literally, you know, we were playing Tampa my first year and they knew that if we lost to Tampa he was getting fired. Again, I'm just a young kid who's naive and taking this all in second, third hand. But we literally had players before the game and at half time saying, "If you make a tackle, if you catch the ball, if you play any good I'll kill you." And we went out and lost the game. We lost the game on purpose and sure enough Coach Bullough was fired and Marv Levy was hired. And really that was all she wrote. You put the combo of Bill Polian and Marv Levy together and magic happened."'
Bills will reportedly host Mississippi WRs DK Metcalf and A.J. Brown
'The Bills sit at ninth overall in the 2019 NFL Draft, which could be in range for a player like Metcalf to fall to them in the first round.'
The Stadium Wall (Community)
Join in the Bills discussion at Two Bills Drive!
Important Off Season Dates for NFL
Super Bowl Tickets Selling for Record Amount
Tennessee Titans in Search of New DC - Could Impact Buffalo
Tampa Bay and Indy are the most intriguing teams for veteran free agent QBs QB
[Name Only Title] lesean mccoy
What I learned from the Titans-Chiefs Championship game
Senior Bowl week
Buffalo Bills Schedule
09/08 @ Jets 1:00 pm
09/15 @ Giants 1:00 pm
09/22 Bengals 1:00 pm
09/29 Patriots 1:00 pm
10/06 @ Titans 1:00 pm
10/20 Dolphins 1:00 pm
10/27 Eagles 1:00 pm
11/03 Redskins 1:00 pm
11/10 @ Browns 1:00 pm
11/17 @ Dolphins 1:00 pm
11/24 Broncos 1:00 pm
11/28 @ Cowboys 4:30 pm
12/08 Ravens 1:00 pm
12/15 @ Steelers 1:00 pm
12/22 @ Patriots 1:00 pm
12/29 Jets 1:00 pm
Buffalo Sabres News
20 thoughts on the state of the Sabres entering the All-Star break
Rasmus Asplund, Lawrence Pilut, Scott Wilson assigned to Rochester
Sabres send Rasmus Asplund, Scott Wilson and Lawrence Pilut to Amerks
The Sabres send three to Rochester
Sabres assign Asplund, Pilut and Wilson to Rochester
Monday's Rochester Coverage
Predators' third-period surge causes 'pain' for Sabres entering bye week
The Aud Club (Community)
Join in the Sabres discussion at SabreSpace!
Alumni Jerseys Misspelled.
Asplund, Wilson and Pilut returned to Rochester
Bogosian should be waived.
GDT - Saturday, January 18th, 2020 - Sabres @ Predators, 8pm ET (WGR/MSG)
Practice Lines 1-17-20
February 24th - Trade Deadline Primer
GDT - Thursday, Jan 16 - Sabres @ Dallas - 8pm ET (WGR,MSG)
Two Bills Drive Archives
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Join us every other Friday for a story, craft and snack. All activities free!
Join us every other Friday for a story, craft and a snack. All activities are free and reservations are not necessary. We begin the story at 10:30 am. Hope you can join us!


Russia's top ballet and opera companies and classical music orchestras need little introduction. This is your chance to see them in their element at grand performance halls such as Moscow's Bolshoi and St Petersburg's Mariinsky Theatres. Popular forms of live music are common in cities and jazz is particularly loved in St Petersburg. Cinema is also well patronised, though you'll struggle to find movies screened with English subtitles.
Teatralnye kassy (theatre ticket offices, sometimes kiosks) are found across all sizeable cities, although it's not difficult to buy face-value tickets from the kassa (ticket office) at the venue itself, typically open for advance or same-day sales from early afternoon until the start of the evening show.
Outside the major cities tickets can start as low as R100. Only the most popular shows tend to sell out completely, so there's usually hope for obtaining same-day seats. In Moscow and St Petersburg, however, competition is much greater and the top venues have 'foreigner pricing'. It can be worth falling back on a hotel service bureau or concierge to get the best tickets, even though that can mean paying a huge premium over face value.
Tickets for both Moscow's Bolshoi and St Petersburg's Mariinsky Theatres can be booked online usually three months or more in advance – this is the best way to ensure that you get the seat you want. For Moscow events, consider booking using a web-based service such as www.parter.ru.
If all else fails, there are usually touts (scalpers): not only professionals but also people with spares. It's standard practice to sell tickets outside the main entrance before starting time. Remember that prices are a free-for-all and you run the risk of obstructed views. Before handing over any money, make sure that the ticket actually has the date, performance and section you want.


This week, the boys kick off the show with cocktails and weekends. Moving into the Dish, Chris discusses bipartisan bills cosponsored in both Houses of Congress, and Trish keeps it gay with shoutouts to Disney and the first openly gay NFL cheerleader making history.
Returning from break, GayTalk welcomes Dr. Evan Goldstein for this month's "Tales from the Tale." Before "Putting a Rubber on It," Trish introducing a special segment spotlighting one of our beloved listeners, mothers, and friends. Be sure to tune in!


Located in the Death Valley National Park, approximately 120 miles northwest of Las Vegas, NV (an easy two-hour drive) and 300 miles northeast of Los Angeles.
Lake Mary Road in the Lakes basin. Scenic day rides, pack trips to the backcountry, drop off services, fishing and hunting trips, and a variety of photography and paintng workshop trips.
McGee Canyon near Crowley Lake. See spectacular scenery on daily trail rides for 1, 2, or 4 hours or All Day. Pack trips. Wilderness Pack trips to favorite destinations, fishing, mountain climbing, and hiking. Have a picnic on lovely Mcgee Creek and shop in the store. Ranch vacations for the adventurous, including Trail Drives.
If you're looking for fun with horses, horses, horses, The Millpond Equestrian Center is the place. Dressage, English, Western Lessons, guided rides in the Sierra Foothills and more.
Offering High Sierra Pack Trips in the Entire High Sierra. Spot trips, trail rides, hiking with pack stock, base camps, dunnage packs and cache, Owens Valley horse drives, continuous hire of packer and stock, cattle drives.
Old Mammoth Road to Sherwin Creek Rd. Trail rides, lessons, boarding, hay rides, special events, weddings, and store. Boarding offered by the day, week, or month.
Horseback trail rides for the whole family; 2, 4, and 8 hour rides. Also offering full range of wilderness pack trips into the Hoover Wilderness and Yosemite National Park. Located in the Eastern Sierra between Bridgeport and Lee Vining.


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PS5 Will Be Limited At Launch
By Nathan Simmons/Updated: April 29, 2020 12:01 pm EST
If you were hoping to get a PlayStation 5 when it is finally released, you may want to preorder it when you can. Bloomberg is reporting that sources close to Sony is expecting a much smaller production run of the new console than everyone may have anticipated.
According to Bloomberg's sources, the initial product run for the PlayStation 5 will be around 5 to 6 million units for the first fiscal year. To put this in perspective, Bloomberg notes that Sony sold 7.5 million PlayStation 4 units within just the first two quarters after that console was released. There are a few different reasons why this may be happening, so let's break down what we know and compare it to the information provided by Bloomberg's source.
It would certainly be easy to pin these production slowdowns on the ongoing outbreak of COVID-19, which has had a massive impact on the gaming industry. However, it appears that this is not the case. According to Bloomberg's anonymous sources, only the marketing side of the PlayStation 5's release has been affected. Production and manufacturing continues on as normal, which means that the decision to narrow down the number of units produced is unrelated to the outbreak.
So the real reason behind the smaller number of produced units appears to come down to cost. This actually lines up pretty closely with what we've heard before regarding the PS5's production woes. The materials used in production are reportedly more expensive and much more scarce than what Sony has used in past generation consoles, which is expected to drive up the price considerably. Analysts expect that Sony will have to sell the console for at least $450, if not more, to break even.
It is very possible that Sony will have to find ways of marketing the new system strictly online and through social media. With the ongoing outbreak, the odds of the company holding any kind of press conference open to the public are slim. This means no one in the press is likely to get a hands-on look at the current build of the PlayStation 5 until right at launch.
If Bloomberg's sources are to the believed, we are already seeing the effects of the outbreak on Sony's PlayStation 5 marketing plans — and no, we're not just talking about the painfully dry PS5 spec presentation from a few weeks back. The impact on Sony's marketing plan can be seen in the recent unveiling of the PlayStation 5's DualSense controller. Bloomberg reports that Sony "was forced to reveal its DualSense PS5 controller in a hurried fashion, according to people informed on the matter."
Granted, the reveal of the DualSense has garnered quite a bit of press for Sony and it's upcoming system. When BossLogic is making memes inspired by your hardware, then you must be doing something right. Still, that's only a small piece of a much larger puzzle. Consumers still don't know a whole lot about what to expect from the PS5. Now there's the potential for many consumers to not even get their hands on it.
Granted, 5 million units is still a lot, and there's the possibility that Sony is expecting less people to be able to actually afford the console. A lot of folks are out of a job or on leave while businesses are closed due to the pandemic. Combining this with the expected high cost of the console, Sony may simply be trying to play it safe. It will already be difficult for the company to break even with these consoles, so the smaller production run could be Sony's way of ensuring that it doesn't make more than necessary.
It should be noted that Bloomberg's sources believe Sony has a separate plan for folks who don't go in for the PlayStation 5. In an effort to continue growing its customer base, Sony is expected to considerably cut the price of the PlayStation 4 and PS4 Pro. Bloomberg's sources implied that Sony "may cut these prices around the time of the PS5 launch to stimulate new subscribers for the PlayStation Plus membership program and PlayStation Now game-streaming service."
All of this adds up to a pretty clear picture that the PlayStation 5 launch will not be at the same scale as previous console generations. Whether or not this means that Sony is simply playing it safe and will widen the release after the first year remains to be seen.
Sony has thus far declined to comment on any of this, but it's unlikely the company will stay silent on this for very long. Again, the new console is meant to arrive this holiday season. It wouldn't come as much of a surprise to hear something more concrete in the near future.


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Giulio Beltramo
Heartbreak I've Become
Available on all streaming platforms
This is Giulio Beltramo's third release as an independent composer, lyricist and artist. From the outset Giulio has been influenced strongly by the Alternative music genre, in its allowance of expressive lyrics and more explorative melodic and harmonic composition.
Heartbreak I've Become was written in Cape Town, South Africa, and is most probably the most personally specific piece by the artist. However, in keeping with accordance of Giulio's intentions, the song still offers a profound sense of relatability allowing for a subjective emotional connection with each of its listeners.
Giulio's musical journey began in 2017 with the release of his debut album Upside Down Inside Out. This was an essential learning opportunity for the artist and took him to the United Kingdom on a mini-tour, performing at various spots round the country including the 02 Academy Islington. Upon his return Giulio embarked on the production process of What A Mess, the artist's second release and most successful release to date with over 66,000 streams on Apple Music and 20,000 on Spotify. The song was too featured on Apple Music's Best of the Week as well as Alternative Music Hot Tracks, and on Spotify was featured on the New Music Friday and Chilled Music playlist, as well as Future Fresh Mzansi.
Giulio has been steadily growing his audience and fan base with various concerts across the country, as well as being featured on a Popsicle TV session and hosted on the Expresso Morning Show.
With the release of Heartbreak I've Become, comes a music video and a collection of concept photos. This marks the first release of 2019 for the artist, however will be one of a few to come this year. Since the release on Friday the song has been added to Apple Music's Best of the Week, as well as Hot Tracks, and on New Music Friday on Spotify.
Heartbreak I've Become 3:24
What A Mess - Single
The song was written whilst I was on a tour in England, specifically London. Essentially at the core level the song is about a break up that was done in an uncourageous manner. One that was made harder due to the emotional connection that was grounded in presumed openness. My works are not however objectively specific, but rather subjectively relational, thus was inspired by numerous heart breaking departures in my life, and continues to represent a multifaceted stance towards all aspects.
Upside Down Inside Out
Giulio Beltramo's debut solo album as an independent artist. The album pays homage to a period on the artists' life. It is episodic in nature and influenced by the life experienced and surrounded by him throughout 2017. Written, arranged and composed by Giulio Beltramo we see an alternative, singer-songwriter styled work that is true and wholesome.
Electronic Press Kit Download
Giulio Beltramo's Electronic Press Kit 3.12 MB
Divide & Conquer album review


Lincoln Beach Amusement Park was opened in 1954 and was a popular attraction for African Americans in New Orleans. It closed in 1964. On the stage at Lincoln Beach many extraordinary musicians performed, including Fats Domino, Sam Cooke, Little Richard, Ink Spots, Earl King, Papa Celestin, Ray Charles, Nat King Cole, Ernie K-Doe, Irma Thomas, The Neville Brothers, Deacon John, Guitar Slim.
The Lake Pontchartrain Causeway is completed as a two lain single span. It was at that time the longest bridge in the world. In 1956, The Causeway captured the title. When the second span of the Causeway was completed in the late 60's it became the 'World's Longest Bridge'. This postcard reads (on back) Lake Pontchartrain Causeway, World's Longest Bridge. Connecting New Orleans with the highlands to the north. It was completed in 1956. The Greater New Orleans Expressway System.
Features "Laff in the Dark"
The $10,000 fish THE CERAMIC JAX BEER MUG READS "1958 AWARD PRESENTED TO A TRUE FOLLOWER OF ISAAC WALTON AS A WINNER IN THE "JAX" GOLDEN GILL FISH HUNT". As the story goes (I can't verify this) THE JACKSON BREWING COMPANY TAGGED FISH, PUT THEM IN THE LAKE, AND AWARDED PRIZES TO FISHERS WHO CAUGHT THEM. I"M TOLD THAT THE $10,000 FISH WAS NEVER CAUGHT. But apparently some fish, with lower valued tags where caught, brought in, and awarded prizes from Jax.
Elvis Presley's movie "King Creole" included scenes filmed at a New Orleans lakefront camp. We're not sure which camp this was. 1958 - Elvis films King Creole Ending scenes feature (a not entirely succesful) escape from gangsters to a Lake Pontchartrain camp off Hayne Boulevard. Footage includes views of many camps in the area.
Rare photo of Sharkey performing (as a wedding gift) on May 15, 1954 at the wedding reception of Sharkey's grand-niece, Phyllis Sanders and her groom, Gerald Duplantier. Phyllis is the daughter of Gladys Quarrella and Gerard Sanders. Gladys is the daughter of Marie Bonano (Sharkey's older sister) and John Quarrella. The reception was held at Lenfant's in New Orleans. According to Margo Duplantier Rhinehart (who shared this information as well as the photo) "Marie Bonano was 10-11 years older than Sharkey. Marie told me that it was she who bought Sharkey his first cornet. I'm under the impression that Marie had a hand in Sharkey's upbringing in his later childhood. She and Sharkey were definitely close. I remember him visiting us often. Marie lived with us from before the time I was born until her death when I was age 22. Actually, we were four generations living in one house for as long as I can remember." Thanks to Margo Duplantier Rhinehart for this information and photograh.
Formerly the U.S. Navy Air Station, the Louisiana State University of New Orleans site was acquired in 1956 under a 99-year lease. After renovation of existing buildings, classes were offered in 1958. The school, late re-named the University of New Orleans, became a full four-year university in 1961. The photo show the general area in 1948, and includes the air station and Pontchartrain Beach. During the 1930s this area would have been known as "Milenburg"--the local pronunciation of Milneburg.
Apparently issued during Elvis' performance onstage at Pontchartrain Beach.
1958 ticket says "This ticket is redeemable at any Merchandise Store, Ride, Amusement Game, Restaurant, Food or Confection Stand at Pontchartrain Beach, New Orleans, Louisiana. "
1959 Bali Hai was the Beach Comber???
A 1959 CERAMIC POLYNESIAN DRINK CUP FROM "THE BEACH BEACH-COMBER" AT PONTCHARTRAIN BEACH. THE "BEACH-COMBER EXISTED FOR ONLY ONE YEAR (I'M TOLD) BEFORE BEING RE-NAMED "THE BALI-HAI. Look closely at this glass (as opposed to the one below it) to see that "Beach-Comber" was later replaced with "Bali-Hai".
The New Basin Canal, just south of Carrollton Avenue, 1951.


ReGel polymer-based delivery of interleukin-2 as a cancer treatment.
Samlowski WE, McGregor JR, Jurek M, Baudys M, Zentner GM, Fowers KD. ReGel polymer-based delivery of interleukin-2 as a cancer treatment. J Immunother. 2006;29(5):524-35.
ReGel is an aqueous, filter sterilizable ABA tri-block polymer consisting of poly-(lactide-co-glycolide) and polyethylene glycol. We tested the suitability of this polymer to provide sustained interleukin-2 (IL-2) delivery for cancer immunotherapy. ReGel/IL-2 is liquid at or below room temperature, and is easily injectable through narrow gauge needles, but undergoes a reversible thermal transition into a bioerodible depot at body temperature. We demonstrated that ReGel/IL-2 releases IL-2 over 72 to 96 hours in vitro, without loss of bioactivity. Pharmacokinetic studies after peritumoral injection of 0.1 mL ReGel/IL-2 in mice demonstrated an early burst of IL-2 release, followed by more sustained release kinetics over 96 hours (T(1/2)beta 48 h). Less than 1.5% of the injected dose was detectable in blood or kidneys during the first 48 hours. A single peritumoral dose of ReGel/IL-2 [1 to 4 million international units (MIU) ReGel/IL-2, split into 4 quadrant injections] was administered to mice bearing subcutaneous RD-995 spindle cell carcinoma. Only the highest dose of ReGel/IL-2 tested (4.0 MIU) resulted in significant hypotension on day 3 after injection. Weekly treatment of Meth A fibrosarcoma and RENCA renal carcinoma with ReGel/IL-2 (2 MIU/dose) induced a significant reduction in tumor growth and improved survival. Reduction in tumor growth at implants remote from treated lesions was also observed, suggesting systemic activation of antitumor immunity. These findings establish that peritumoral injection of ReGel/IL-2 is an effective delivery system for cancer immunotherapy, while decreasing IL-2 toxicity. This polymer delivery system is likely to be broadly applicable for sustained delivery of other cytokines and peptides.


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Luke Heyerman
Luke believes in the relentless and brave pursuit of questions. They are creative adrenaline.
Friction is a point of emphasis. As the famous Hollywood saying goes, "A happy set is a box-office flop." Luke promotes collaborative conflict in all creative endeavors—like a plow meeting hard ground to unearth vital insights and yield a more vibrant crop.
Every brand is part of a story, and applying an eclectic range of skills, Luke helps brands define that narrative and express their role within it. He falls in love with each character, each cause, each product. On Walmart, he helped lead the largest omnichannel, multi-agency campaign of its time and the most successful social campaign of the Holiday season. Luke has also created global campaigns for American Express, Cisco, Facebook, HP, Salesforce, and Xerox.
On his winding path to here, Luke has also acted in Hollywood, authored children's books, written plays and novels, taught science and music in South Central, and whispered instructions in surgeons' ears as they implanted orthopedic devices.
See all of us
BA, English, University of California, Santa Barbara
Studied at Playhouse West, Los Angeles
Education Director, Sowelu Theater, Portland
Blog articles by Luke Heyerman:
A human guide to brand behavior
Meet our crew!
We're storytellers, strategists, account and project managers and all-around go-getters. Learn more about our talented team.
Now you'll always be on top of what's happening in and around AHA. We're excited to share fresh insights and bold ideas on brand, purpose and marketing—and other topics we geek out over.
Lessons from a year of listening
Driving social change, pint by pint
A peek into our Praxis process
360.750.1680 | 415 W. Sixth St., Suite 605, Vancouver, WA 98660
AHA. All rights reserved.


Christmas is often a time of reflection while also looking forward to the year ahead. It can be a very special time when family and friends gather to share their memories, hopes and dreams.
However, for some it can be a lonely time as loved ones have been lost or are being lost. It is a time when reaching out, appreciating and valuing others goes a long, long way in supporting us to be of healthy body and mind and I wish you all strength and courage to reach out to those people in your life who are and could be special to you.
Together in MindWise have achieved so much this year and we are set to achieve so much more in 2019!
The continued development of our housing service to meet the needs of older people experiencing fraility, dementia and mental health.
The Personality Disorder Conference with thanks to the NI Personality Disorder Network for all their support.
The development of our Impact Measurement best practice tools.
The development of our new Carers strategic intent.
The establishment of our Autism Special Interest Group.
Securing and operationalisation of our first Homelessness and Mental Health Hostel.
Achieving Investor in People Gold.
Further cost pressures across statutory contracts.
Brexit remaining in a state of flux.
Of course you will have your owns reflections on the year, some of which will include family, friends, colleagues and clients who have left us – to them all we wish every success and hope they will always be ambassadors for MindWise. Not least Charles Bamford, Board of Trustees Chair, who has recently retired from his role and who must be thanked for his many years of contribution to MindWise.
We have much to look forward to in 2019, during which Tom Haire, our new BOT Chair, will formally introduce himself to you all. No doubt we will continue to sustain and develop MindWise through our passion and commitment to delivering high quality service provision for and with our clients.
As we go forward and face no doubt some new challenges, I have no doubt we will succeed Together and make a real difference to the many people we engage with across Northern Ireland and beyond as we move from recovery to discovery.


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Osoby o tym nazwisku:
 Atanazy (Mironescu) – prawosławny biskup
 Gheorghe Mironescu – rumuński polityk i dyplomata

redpajama_set_name: RedPajamaWikipedia


Attention all Rock & Republic fans: The denim label beloved by stars like Mary-Kate Olsen and Victoria Beckham is launching a brand-spanking new makeup line this week at Bloomingdales, Neiman Marcus and Nordstrom. And just like their jeans, the products are wearable with a funky twist. While some of the price tags are a little glamorously over-the-top (like the $225 Accentuate bronzer/highlighter duo in a Swarovski compact), most fall more in the "I-deserve-it" splurge category (think between $20 and $40).
My favorite? Their highly pigmented eye shadows, which you can layer on to get some truly intense, color. Check it out and let us know what you think!


When your Maple Grove, MN home's roof is leaking, or has been damaged from a storm, you need a team of experienced roofers on the job as soon as possible. Your roof protects your home, your possessions, and your family. A simple leak may seem like nothing to be concerned about, but it can easily lead to mold. Many people ask, "are there quality MN roofing contractors near me?" It's not always easy to spot these services, but there are experts out there. Versatile Roofing Pros, Roofing Contractors in Maple Grove MN, for example, offers a wide variety of roofing services, including roofing, siding, window treatments, gutter installation and repairs, and water damage restoration in Minnesota.
Window Installation – Are your windows looking a bit dingy? Sometimes, a good cleaning is all it needs, but sometimes it's more than that. We can repair damaged panes, install new windows, and upgrade your existing windows to more durable options. By improving your windows, you don't just make it easier to see the world, you can also improve your heating and cooling efficiency, which translates to savings on your utility bills.
As a reputable Maple Grove Minnesota roofing company, you know you can depend on us for all of your local roofing needs. Our experience in the roofing industry speaks for itself. Don't trust your MN home to anyone who doesn't have your full confidence—trust in the roofer near you who has a proven track record.
If you're searching for a great roofing contractor in your area, we're here for you. With years of experience, top of the line equipment, and a dedication to excellence, you won't find a better local company. Your roof is your first line of protection from the elements, making it vital that you have any damage repaired as soon as possible. Contact us today for a free estimate.


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Q: GMAT work rate problem. Person A makes 300 cakes in 2 hours. Person B makes 300 cakes in 2 hours. Person C makes 300 cakes in 3 hours
How long does it take all 3 working together to make 300 cakes.
(Assume no synergies and rates are additive. So Person A and Person B would make 600 cakes in 2 hours together).
So I wasn't sure what to do here so I tried to figure out the per hour rate of each.
Person A makes 150 cakes in an hour.
Person B makes 150 cakes in an hour.
Person C makes 100 cakes in an hour.
So that wasn't getting me anywhere. All I know is that in an hour, they all make 150+150+100 = 400 cakes. So, to make 300 cakes, they need less than 1 hour.

A: Let's back up and go back to your observation, and complete the thought:
If together they are able to make $400$ cakes in an hour, then to make $300$ cakes takes them $$\dfrac{300}{400} \text{hours} = 45\text{ min}$$
We can also setup the problem as one of ratios: $$\dfrac{400}{1 \text{hour}} = \frac {300}{x\text{ hours}}$$ and then solve for $x$

A: Another way to tackle it is, you can think of work problems like distance problems.  Just like ratetime=distance, ratetime=work
When you have several people working together, you add their rates together.  You did a great job of finding this, so we know that they make 400cakes/hour (which is their rate together) to find out how long it takes them to make 300 cakes we use the work equation and solve for t (time)
400c/h*t=300
so like was said before, t=3/4 of an hour or 45 minutes

redpajama_set_name: RedPajamaStackExchange


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Home / News / New insights into how blood vessels control bone formation
New insights into how blood vessels control bone formation
1 April 2019 Research News
People are living longer than ever before globally. While this is a major achievement of modern medicine and healthcare, it does mean that a growing proportion of the population is made up of older people and all the associated implications. A report in 2018 from the Office of National Statistics projects that by 2066, a quarter of the UK population will be aged 65 or over. This highlights, more than ever before, that we need to find ways to help our aging population age healthily. Almost all aging individuals show bone loss leading to increase in risks of fracture, which also take longer to heal than a younger adult, and are more likely to suffer from conditions like osteoporosis and arthritis.
Research published on 1 April in Nature Cell Biology by the Integrative Skeletal Physiology group at the LMS has uncovered how the blood vessels in bone are involved in regulating bone formation, which could have implications for a healthy aging population.
Whether it is during normal growth and development or during healing or repair, most types of bones are formed through a process involving, first, the formation of an intermediate cartilage structure. For example, the elongation of long bones happens through the conversion of growth plate cartilage, which is found at either end of the bone, into bone tissue. The cartilage structure is broken down by cells called osteoclasts, before another type of cell called osteoblasts help lay down the bone tissue around the vast network of blood vessels that can be found there. Though bones are highly laced with capillaries, we are at the early stages of understanding the functions of these blood vessels.
In this study, researchers showed that a specialised subtype of capillaries, termed type H, play a central role in replacing the cartilage matrix with bone. Specifically, the endothelial cells that associated with the capillaries had this proteolytic activity, or ability to breakdown and digest the cartilage matrix, that was earlier thought to belong to osteoclasts. This is also a previously unknown function of these blood vessel that is reported in this study. Moreover, these capillaries were found to control the growth direction of bone, as bone growth was always orientated towards the blood vessels. When the researchers changed the direction at which the blood vessels were growing, the direction of bone growth also changed. This highlighted how these endothelial cells from blood vessels can shape bone elongation by digesting the bone matrix.
This transverse section of bone shows distribution of blood vessels near cartilage region. Blood vessels were immunostained for the expression of markers, CD31 (green) and endomucin (red). Type H capillaries (yellow) are in close proximity to chondrocytes. DAPI (blue) is a nuclear counterstain.
But these endothelial cells also have a support act. This study also identified a new type of osteoclast. This cell type isn't able to digest the bone matrix, but instead helps the blood vessels in their directional growth.
How could this research help our aging population?
As previously mentioned, an aging population means more strain on healthcare services with regards to fracture healing and conditions like arthritis. In fractures, for example, cartilage models need to be laid down before they are removed to make way for new bone. But this repair process takes much longer in older people, so this research could be used to accelerate the function of the endothelial cells to improve the repair more quickly. On the other hand, in conditions like arthritis, there is excessive cartilage damage and excessive blood vessel infiltration, so this research could help pave ways to stop the action of these endothelial cells in arthritis to reduce cartilage damage. This is exactly the direction that these researchers want to take this research next.
Saravana Ramasamy, Head of the Integrative Skeletal Physiology Group, discusses the next steps:
"We have uncovered this interesting function of blood vessels, but the mechanism of how we can control this function is not very well understood. However, it is clear that blood vessels are involved in shaping the architecture of bone tissue. Therefore, we want to move forward by collaborating with fracture repair and arthritis animal models to investigate whether we can locally control the proteolytic actions of the endothelial cells"
'Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation' was published in Nature Cell Biology on 1 April.
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