Wild animals captured and made to perform circus tricks.
Dogs against dogs and cockerels against cockerels; forced to fight to the death.
Horses and dogs raced until they are worn out; their monetary value gone.
These examples are but a few of the countless exploitive practices that have all been classified by many as 'entertainment'. Release is a non-profit foundation, which campaigns to raise awareness around the suffering of animals used in entertainment. Its goal is to educate the public about the horrors that animals suffer for the pleasure of humans and to encourage people to boycott any industries that use animals for entertainment. Our aim is to live in a world where animals no longer suffer at the hands of humans and where our pleasure comes secondary to their pain.
A polar bear has one million times less space in a zoo than it does in the wild.
Through the use of Twitter, Facebook, websites, leaflets, stickers and posters, Release is spreading the word. Rather than visiting the zoo, why not visit a local ecology centre? Or the Natural History museum? Or watch a wildlife documentary? These are all far more educational than watching no-longer-wild animals pacing and rocking behind walls of glass and bars. How about donating money to conservation? Or adopting an animal? Protecting animals in their natural habitat is, of course, far more beneficial to their species overall. Attend circuses with only human performers; bet on sports with only human participants; watch boxing or UCF; or go scuba diving to witness sea-life. There are many forms of enjoyable entertainment which do not require animal participants and there are plenty of peaceful and non-detrimental ways to interact with and learn about animals.
In marine parks, many orcas do not live past the age of ten, yet in the wild they can live for decades.
We believe that if the majority of people become aware of the abuse that goes on, they will no longer be willing to support and perpetuate it. Of course there are those who are fully aware of the abuse. Those who participate in and profit from the practices are unwilling to recognise the suffering, since they will then be out of pocket. However, we believe that the majority of people see past profit. Their compassion triumphs over greed. These are the people we need to stand up and speak out against these practices. These are the people we need to give their voice to the voiceless.
These are the people that have the power to Release the animals from their suffering.


text:
Carriera professionistica

Carolina Panthers (2010)
Uscì dal college ma non venne scelto al draft. Il 30 aprile firmò con i Panthers. Il 4 settembre venne svincolato per poi rifirmare due giorni dopo con la squadra di pratica. Il 22 dicembre fu inserito sul roster ufficiale della squadra. Il giorno dopo debuttò nella NFL contro i Pittsburgh Steelers. Il suo debutto da titolare avvenne il 2 gennaio 2011 contro gli Atlanta Falcons come fullback.

Il 31 agosto 2011 venne svincolato dai Panthers.

Oakland Raiders (2012-presente)
Il 9 gennaio 2012 firmò con i Raiders ma il 29 agosto venne messo sulla lista infortunati per un infortunio all'anca.

Vittorie e premi
Nessuno

Statistiche

Note

Collegamenti esterni

Giocatori dei Carolina Panthers

redpajama_set_name: RedPajamaWikipedia


The primary goal of the Missouri Overdose Rescue and Education (MORE) project is to reduce opioid-involved deaths in Missouri through training, education, and distribution of naloxone to first responders in rural regions of the state. The State of Missouri Department of Health and Senior Services (DHSS) will lead the project partnering with Missouri Heroin Overdose Prevention and Education (MO-HOPE) project, Missouri Institute of Mental Health (MIMH), and the State of Missouri Department of Mental Health (DMH).
For more information regarding MORE please contact Karen Wallace, MORE Project Coordinator at (573) 751-6839 or Karen.Wallace@health.mo.gov.
Complete the no cost, required Overdose Education and Naloxone Distribution training for their department.
Once the training sign in sheets and signed MOU has been received, your agency will receive notification of shipment and where to pickup the naloxone.


text:
Home Events Dancers Choreographers Support About Connect GALLERY
HomeEventsDancersChoreographersSupportAboutConnect
Miami's Iconic Contemporary Dance Company
Plgdc guest choreographers
Jacqueline Bulnes
Dancer/Director, born in Miami Florida, she began her early training with E. Ronquillo of the Ballet Nacional de Cuba. She continued her studies at the New World School of the Arts, where she received a BFA with honors. Ms. Bulnes has received scholarships to American Ballet Theatre,
Dance Theatre of Harlem, and the Martha Graham School, and received a Merit Award at the NFAA "ARTS" Competition. While at New World, Jacqueline was a featured dancer in a series of short dance films titled "Scriptures," directed by Jennifer Sims, and shown at Memento Vivere Festival (Italy and Romania 2009), Festival VideoDanzaBa (Buenos Aires, Argentina 2010),
Stratford Fringe Film Festival (England 2010), Court-BOUILLON Film Festival (France 2010) and NYC Short Film Festival (NYC 2010). Jacqueline has danced as a soloist with Dance Theatre of Harlem and the Martha Graham Dance Company where she performed leading roles. She was the lead Actress in "Proserpina", directed by Federico Tocchella as well as lead Actress/Dancer in Academy Award Winner Bill Laurence's music video "After Sun." In the summers of 2016 & 2017, she was chosen by Robert Cohan as a Choreographer during the "Cohan Collective" residency in London where she had the honor of restaging Martha Graham's "Panorama" and will be returning in the summer of 2018 to restage "A Choreographic Offering" by Jose Limon with whose company she is currently performing in NYC.
Kashia Kancey
Kashia Kancey is a young dancer who was born and raised in Miami, Florida. Currently, she is completing her studies at New World School of the Arts in the college track. She has been dancing for nine years and received as training from both New World School of the Arts High School and the Miami Arts Charter School. Kaisha began to choreograph at the age of sixteen, first exploring movement within herself and with her own body, then proceeding to create her first official piece titled "Abel," which premiered in the Student Choreography Showcase at the New World School of the Arts. Her work "Every Day Is February" was presented in December 2017 at the "Rhythmic Atlantic" program for the Victoria London Choreographers Showcase; she also designed the costumes for her dance.
Justin Rapaport
Justin Rapaport is from Miami, Florida, and studied dance at The Juilliard School in New York City under the guidance of Lawrence Rhodes, Risa Steinberg, Alphonse Poulin, Terese Capucilli, Linda Kent, Alexandra Wells, and Andra Corvino. Rapaport has performed various original works by Martha Graham, Jose Limon, Twyla Tharp, Brian Brooks, Alejandro Cerrudo, Sharon Eyal, and Daniel Lewis. He has been to many summer dance programs including Netherlands Dance Theater, Springboard Dance Montreal, Jacob's Pillow Contemporary, Hubbard Street Dance Chicago, American Ballet Theater, and Miami City Ballet. He began his formal dance training at the age of eight at local studio Dance Empire under the guidance of Angel Fraser-Logan, Jamar Roberts, Tawanna Hall-Charlton, Liana Navarro and Tony Catanzaro and continued his studies at NWSA High School where he trained in classical ballet and various modern techniques under the guidance of Bambi Anderson, Gerard Ebitz, Daniel Lewis, Peter London, Rebecca Cannan, Lara Murphy, Tina Santos-Wahl, Ruth Wiesen, Dale Andree and Arnold Quintane. His ballet "Leah (A Rose for Israel)" premiered at Beth Shmuel Cuban Hebrew Congregation (Miami Beach - October 2015) in a program by the Peter London Dance Company where he also presented a solo dance of his work titled "Toasties." After receiving his BFA in dance at Juilliard, Justin joined Ballet BC, a professional contemporary dance company based in Vancouver, British Columbia.
Leon Cobb
Originally from Miami, Leon Cobb started to dance at 17 at Southern Dance Theatre. When he was accepted into the New Words School of the Arts Conservatory Dance program, Cobb met Peter London, a former Graham dancer, who took him under his wing and extended his modern dance training. "Modern dance requires a mental focus that separates you from the average dancer," says Cobb; he likes a challenge and knew that this is what he wanted to do for the rest of his life. In the past six years, he has been blessed with scholarships to some of the top modern dance and contemporary ballet schools and has worked with top choreographers. One of the highlights of his time as an apprentice with the Martha Graham Dance Company, was his appearance in the all-male performance of Graham's "Celebration!" at New York City Center on April 18, 2016. More recently,
Cobb signed a contract with the prestigious Limon Dance Company.
Lloyd Knight
Lloyd Knight was born in England, reared in Miami, and trained at the Miami Conservatory of Ballet. He has a BFA from the New World School of the Arts, where he worked with many renowned choreographers, including Donald McKayle, Robert Battle, Peter London and Michael Uthoff and performed leading roles by Jose Limon and Merce Cunningham. He received full scholarships to the Alvin Ailey American Center, to Dance Theatre of Harlem and to The Martha Graham School. Knight joined The Martha Graham Dance Company in 2005, was promoted to Soloist in 2009, and performed starring Roles in "Appalachian Spring," "Embattled Garden," and "Errand into the Maze," among others. In addition, Knight has taught dance at Ballet Hispánico (New York City), New World School of the Arts and The Martha Graham School. Knight has performed in the touring show of "The King and I," directed by Guy Stroman. In a collaboration with photographer Mark Andrews, the exhibit on "Steel: Lloyd Knight, The Physique of a Dancer," was shown at the National Museum of Dance in Saratoga Springs, NY. Knight was a Model/Dancer for British publication "AnOther Magazine" and Dance Magazine named him as one of the Top 15 Dancers to Watch in 2010. Recently, he partnered Ballerina Wendy Whelan in Graham's "Moon" and Misty Copeland in Graham's "At Summer's Full."
Melissa Fernandez
Raised in Miami, Florida, Melissa Fernández began her classical ballet training at the age of five under the direction of the Cuban instructor Caridad Espinoza. She went on to learn modern dance techniques and to further her dance education at the New World School of the Arts where she graduated with honors in 2008. Upon graduation, she moved to New York City and obtained a BFA from The Juilliard School in 2013. Currently, Ms. Fernández is beginning her fourth season with Ballet Hispánico of New York. Her work "Que se Encuentra en los Arrabales" premiered for the December 2015 performances of the Peter London Global Dance Company's Choreographers Showcase at the Carnival Studio Theater of the Arsht Center in Miami; it was inspired by the history of tango and danced to the contemporary interpretation of Astor Piazzolla's music as played by Yo-Yo Ma. On that occasion, she also performed her own choreography as a "Little Holiday Gift" to the audience.
A proud native of Miami, Lynn is a graduate of the New World School of the Arts (NWSA) where she trained in all forms of dance. While at NWSA, she received a number of scholarships to attend the Alvin Ailey Summer Intensive and was asked to join Ailey II. She attended Florida State University, received two Bachelor's degrees (one in Applied Economics and the other in Interdisciplinary Social Science) and upon graduation, became a member of Spectrum Dance Theater under Artistic Director (and Tony nominated choreographer) Donald Byrd. Her diverse background and training have afforded her opportunities such as being a featured dancer in Scary Movie 5, touring the United States and Canada as a dancer/singer in Disney's "The Lion King," and working with recording artists such as Usher. She played the role of Cinderella at Lincoln Center in the Little Orchestra Society's production and is also a featured dancer in the HBO series Vinyl and in the Netflix Original Series The Get Down, both released in 2016. Sharron holds contemporary and musical theater master classes across the country and is the Founder and Executive Director of Steps Ahead, a program designed to equip emerging professional dancers ages 16 and above with the tools necessary to enter the dance market with utmost professionalism and excellence.
Sharron participated in the Peter London Global Dance Company's First Choreographers Showcase in 2014 with her work "Righteous Moments," danced to Nina Simone's "Feeling Good." She is a New York-based artist looking to inspire and be inspired.
Peter London Global Dance Company, Inc. Copyright 2018
VolunteerAffiliates & SponsorsMediaMake a DonationPrivacy Policy

redpajama_set_name: RedPajamaCommonCrawl


This video will make anyone who's ever suffered from a muscle cramp cringe. Rafael Nadal was settling in for a post-match press conference after a straight-set win over David Nalbandian yesterday when he was suddenly hit with the pain of a stiffened calf muscle.
It's a strange injury to watch unfold, simply because there's no awkward moment when a knee or an ankle bends the wrong way—instead it's just one long awkward moment. The end result is like watching someone experience the longest brain freeze in his life.
For some reason, reporters remained in the interview room for over two minutes, as Rafa squirmed in his seat and waited for the pain to subside. They were finally asked to leave after he slipped off his chair and under the table, and he resumed the Q&A about ten minutes later.
Muscle cramps are in no way lasting, and this shouldn't affect Nadal's chances in the long run. They are just momentarily debilitating and kind of awkward to watch live.
"Not to put a dampener on the story, but people cramp after matches when they're cold," realist Andy Roddick said after the episode. "It's just something that happens... It's just unfortunate it happened in front of [the press]."


Drupal 6 : Créez des sites web de qualité professionnelle, a translation of David Mercer's Building powerful and robust websites with Drupal 6 was presented at the Paris Drupal Meetup last night.
Damien Tournoud took on the task of updating the book's content, providing French screenshots and illustrations and doing a thorough technical review.
First impression: superbe, mon ami.
Due to hit the stores tomorrow, September 12, so if you want to experience Drupal in the language of Voltaire, you know what to do.


You can withdraw your cash at any time, provided your account is validated.
Note: If your linked bank account is denominated in a different currency than the funds in your WhiskyInvestDirect account, make sure that they will accept a payment in your WhiskyInvestDirect account currency. Most banks will automatically convert the funds into your home currency, usually at an expensive rate. Some banks will just reject the transfer and return the funds to us. Please check with your bank before withdrawing.
Log in and select the ACCOUNT button followed by the WITHDRAW FUNDS sub-menu option.
Withdrawals of £20,000 and above will be processed by CHAPS. You can also request this from the withdrawal confirmation page for smaller amounts. Ordinarily a CHAPS payment will reach you on the first working day after you enter your withdrawal request. The bank will deduct £20 for this service.
Withdrawals below £20,000 will be processed by BACS. Ordinarily a BACS payment will reach you on the third working day after you enter your withdrawal request. This transfer is free of charge.
Withdrawals in currencies other than British Pounds will be paid by SWIFT. Ordinarily a SWIFT payment will reach you on the first working day after you enter your withdrawal request. The bank will deduct a fee for this service.
Note: Exact transfer times may vary depending on your bank's service levels. Your withdrawal will show as 'unprocessed' until around 3pm UK time for CHAPS transfers, and around 5pm UK time for BACS transfers.
We will usually pay US Dollars using ACH. We will deduct $10 for this service.
Where an ACH is not possible, or for other currencies, we will pay you using SWIFT. Ordinarily a SWIFT payment will reach you on the first working day after you enter your withdrawal request. The bank will deduct a fee for this service.
Note: Exact transfer times may vary depending on your bank's time zone & service levels. Your withdrawal will show as 'unprocessed' until around 3pm UK time.
Any transfer costs will be taken out of the withdrawn amount - you do not need to allow for charges.


What is Jedox BI & CPM?
Jedox empowers you to analyze historical data for meaningful insight, and to plan and forecast intelligently. Jedox unleashes your capabilities in one solution, unifying Business Intelligence and Corporate Performance Management (BI & CPM).
Why use Jedox BI & CPM?


text:
Tumble Tots (franchise for sale in Oxford)
Tumble Tots currently has an exciting opportunity available to take over an existing business in the Oxford area.
Franchise Info Request further details on this resale
Location(s): Oxford
Selling price: £13,000
Established: Over 30 years
hours: The current franchisee runs 13 classes over 4 days
Clients: 120 established customers
Tumble Tots Franchise for Sale in Oxford
Currently Operating in Abingdon, Botley, Risinghurst and Wallingford
Tumble Tots is a leader in the children's activity sector, with over 40 years of experience in providing early years children with skills for life! By joining the Tumble Tots network you will own your own business whilst being supported to deliver a specially designed programme which aims to enhance a child's physical, social and cognitive development during their most formative years.
Tumble Tots has been operating in the Oxford area for over 30 years, during which time it has built a good reputation and presence in the area. Now available for purchase due to personal reasons, we are assisting the current owner with the sale.
The business requires a fresh injection of enthusiasm which would be introduced by a new owner who can invest more time into the day-to-day running of the business.
The current franchisee runs 13 classes over 4 days and has around 120 current members, there is potential to grow the business within the current schedule and to expand within the territory.
The re-sale includes the following:
A defined territory
Set of Tumble Tots equipment
120 established customers
Online booking platform
Handover period with the current owner (amount of days to be established)
Access to existing social media accounts
Local webpage within national website
In addition, the Franchisor will provide:
Business management training at Tumble Tots (UK) Ltd.
Bespoke Tumble Tots technical training
Annual regional meetings
Tumble Tots marketing pack (including roller banner, posters, and flyers)
Rights to renew the agreement every 3 years
National advertising and marketing including TV and social media advertising
Comprehensive operating manuals
Rights to use trademarks
Full back-up and unlimited ongoing support
A proven system of business operation
If you feel like this opportunity is for you, the next step would be to arrange a no-obligation meeting. You will be able to see some classes in action; look into the business figures in more detail and meet the current owner to get a feel for the day-to-day running of a Tumble Tots franchise.
Please do not hesitate to get in touch if you have any further questions or would like to arrange a mutually suitable date to meet.
Request Further Information About this Tumble Tots Resale Opportunity


Geothermal heat pump Air sealing, duct sealing, insulation/ventilation, compact fluorescent lighting. Solar heated pool, low chemical use. Knephar Dunn Farm is a 300 year old stone millhouse with passive solar and energy efficient renovations and additions. The property is fully powered by a grid-tied PV system with geothermal backup. We also have a solar heated pool, organic gardens and composting, recycling, chickens, goats, peacocks and butterfly gardens. SunPower Builders' passive solar office is on the same site, built with recycled and salvaged materials, and also powered by PV!
Please call for directions and RSVP. 610-489-1105 Pets roam the property- dogs, cats, birds, and other. Follow Pechins Mill Road to dead end (dirt road). Park along left-side of driveway. Low-heeled shoes recommended.


text:
Q: ImportError: No module named suds Having trouble with py2exe importing the suds module, and narrowed it down to the following:
>>> imp.find_module('suds', sys.path)
Traceback (most recent call last):
  File "<stdin>", line 1, in <module>
ImportError: No module named suds

However, a simple import works fine:
>>> import suds
>>> suds.__version__
'0.4'

Here is my sys.path, which shows suds at 'C:\Python27\lib\site-packages\suds-0.4-py2.7.egg':
>>> pprint.pprint(sys.path)
['',
 'C:\\Python27\\lib\\site-packages\\pyyaml-3.10-py2.7-win32.egg',
 'C:\\Python27\\lib\\site-packages\\progressbar-2.3-py2.7.egg',
 'C:\\Python27\\lib\\site-packages\\sqlalchemy-0.7.2-py2.7-win32.egg',
 'C:\\Python27\\lib\\site-packages\\soappy-0.12.5-py2.7.egg',
 'C:\\Python27\\lib\\site-packages\\wstools-0.3-py2.7.egg',
 'C:\\Python27\\lib\\site-packages\\fpconst-0.7.2-py2.7.egg',
 'C:\\Python27\\lib\\site-packages\\python_ntlm-1.0.1-py2.7.egg',
 'C:\\Python27\\lib\\site-packages\\django-1.3-py2.7.egg',
 'C:\\Python27\\lib\\site-packages\\pyodbc-2.1.9-py2.7-win32.egg',
 'C:\\Python27\\lib\\site-packages\\suds-0.4-py2.7.egg',
 'C:\\Windows\\system32\\python27.zip',
 'C:\\Python27\\DLLs',
 'C:\\Python27\\lib',
 'C:\\Python27\\lib\\plat-win',
 'C:\\Python27\\lib\\lib-tk',
 'C:\\Python27',
 'C:\\Python27\\lib\\site-packages']

Confirmed that py2exe is installed under 2.7:
C:\Python27\Lib\site-packages>ls -l py2*
-rw-rw-rw-  1 BEARGLE 0  524 2008-11-10 14:40 py2exe-0.6.9-py2.7.egg-info

py2exe:
total 448
-rw-rw-rw-  1 BEARGLE 0  3092 2008-11-10 14:39 __init__.py
-rw-rw-rw-  1 BEARGLE 0  3177 2011-09-12 14:36 __init__.pyc
-rw-rw-rw-  1 BEARGLE 0  3177 2011-09-12 14:35 __init__.pyo
-rw-rw-rw-  1 BEARGLE 0  4582 2008-06-24 16:32 boot_com_servers.py
-rw-rw-rw-  1 BEARGLE 0  2898 2011-09-12 14:35 boot_com_servers.pyc
-rw-rw-rw-  1 BEARGLE 0  2898 2011-09-12 14:35 boot_com_servers.pyo
-rw-rw-rw-  1 BEARGLE 0  3584 2008-06-24 16:32 boot_common.py
-rw-rw-rw-  1 BEARGLE 0  2252 2011-09-12 14:35 boot_common.pyc
-rw-rw-rw-  1 BEARGLE 0  2252 2011-09-12 14:35 boot_common.pyo
-rw-rw-rw-  1 BEARGLE 0  2941 2008-06-24 16:32 boot_ctypes_com_server.py
-rw-rw-rw-  1 BEARGLE 0  2733 2011-09-12 14:35 boot_ctypes_com_server.pyc
-rw-rw-rw-  1 BEARGLE 0  2733 2011-09-12 14:35 boot_ctypes_com_server.pyo
-rw-rw-rw-  1 BEARGLE 0  7527 2008-06-24 16:32 boot_service.py
-rw-rw-rw-  1 BEARGLE 0  5081 2011-09-12 14:35 boot_service.pyc
-rw-rw-rw-  1 BEARGLE 0  4973 2011-09-12 14:35 boot_service.pyo
-rw-rw-rw-  1 BEARGLE 0 71838 2008-08-30 11:56 build_exe.py
-rw-rw-rw-  1 BEARGLE 0 48498 2011-09-12 14:35 build_exe.pyc
-rw-rw-rw-  1 BEARGLE 0 48330 2011-09-12 14:35 build_exe.pyo
-rw-rw-rw-  1 BEARGLE 0 30327 2011-09-13 09:16 mf.py
-rw-rw-rw-  1 BEARGLE 0 22999 2011-09-13 09:16 mf.pyc
-rw-rw-rw-  1 BEARGLE 0 22876 2011-09-12 14:35 mf.pyo
-rw-rw-rw-  1 BEARGLE 0 13312 2008-11-10 14:40 py2exe_util.pyd
drw-rw-rw-  2 BEARGLE 0  4096 2011-09-12 14:35 resources
-rwxrwxrwx  1 BEARGLE 0 17408 2008-11-10 14:40 run.exe
-rw-rw-rw-  1 BEARGLE 0 19456 2008-11-10 14:40 run_ctypes_dll.dll
-rw-rw-rw-  1 BEARGLE 0 19968 2008-11-10 14:40 run_dll.dll
-rw-rw-rw-  1 BEARGLE 0 20480 2008-11-10 14:40 run_isapi.dll
-rwxrwxrwx  1 BEARGLE 0 17408 2008-11-10 14:40 run_w.exe
drw-rw-rw-  8 BEARGLE 0  4096 2011-09-12 14:35 samples

Why isn't imp.find_module locating the suds module?

A: Extracted the suds egg at:

C:\Python27\lib\site-packages\suds-0.4-py2.7.egg

and created C:\Python27\lib\site-packages\suds directory that contains source files. Module is now found:
>>> imp.find_module('suds')
(None, 'C:\\Python27\\lib\\site-packages\\suds', ('', '', 5))

py2exe build completes successfully. It appears that imp.find_module requires directory with module source files to exist, an egg file is not recognized.

redpajama_set_name: RedPajamaStackExchange


text:
Relative bioavailability of two oral formulations of piroxicam 20 mg: a single-dose, randomized-sequence, open-label, two-period crossover comparison in healthy Mexican adult volunteers.
Clin Ther. 2010 Feb; 32(2):357-64.CT
Piroxicam is an NSAID indicated for the treatment of rheumatoid diseases. Although there are generic formulations of oral piroxicam marketed in Mexico, a literature search did not identify published data concerning the bioavailability of these formulations in the Mexican population.
The aims of this study were to determine the bioequivalence of a generic (test) and a reference formulation of oral piroxicam 20 mg and to generate data regarding the oral bioavailability of this drug in a Mexican population.
This single-dose, randomized-sequence, open-label, 2-period crossover study was conducted in healthy Mexican adult volunteers. Subjects were randomly assigned to receive the test formulation followed by the reference formulation, or vice versa, with a 15-day washout period between doses. Study drugs were administered after a 10-hour overnight fast. For pharmacokinetic analysis, blood samples were drawn at 0 (baseline), 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 6, 8, 12, 24, 48, 72, 96, 120, and 168 hours after administration. Plasma concentrations of piroxicam were determined using HPLC. The test and reference formulations were to be considered bioequivalent if the 90% CIs for the geometric mean test/reference ratios were within a predetermined range of 80% to 125%. Tolerability was determined using clinical assessment, monitoring of vital signs, laboratory analysis, and subject interviews regarding adverse events (AEs).
A total of 28 subjects were enrolled (15 men, 13 women; mean [SD] age, 24 [4] years [range, 19-35 years]; weight, 63.0 [8.9] kg [range, 47.5-81.9 kg]; height, 165 [10] cm [range, 149-179 cm]; and body mass index, 23.2 [1.4] kg/m(2) [range, 20.6-26.0 kg/m(2)]). The 90% CIs for piroxicam C(max), AUC(0-infinity), and AUC(0-infinity)) were 89.98% to 101.04%, 91.46% to 101.19%, and 93.51% to 105.86%, respectively. Thirteen subjects reported a total of 17 AEs during the study. None of the AEs were considered serious or related to the administered formulations. The most common AE was local postvenipuncture ecchymosis, reported in 8 subjects (28.6%).
In this small study in healthy Mexican adult subjects, a single 20-mg dose of the test formulation of orally administered piroxicam met the regulatory requirements to assume bioequivalence, based on the rate and extent of absorption. Both formulations were well tolerated. Mexican national registry code: CE-PEC.0875.
Aggregator Full Text
Palma-Aguirre JA
Centro de Estudios Científicos y Clínicos Pharma, S.A. de C.V., Mexico City, Mexico.
Lopez-Gamboa M
Cariño L
Burke-Fraga V
González-de la Parra M
Administration, OralAdultAnti-Inflammatory Agents, Non-SteroidalBiological AvailabilityCapsulesChemistry, PharmaceuticalChromatography, High Pressure LiquidCross-Over StudiesDrugs, GenericFemaleHumansMaleMexicoPiroxicamTherapeutic EquivalencyYoung Adult
Palma-Aguirre, Jose Antonio, et al. "Relative Bioavailability of Two Oral Formulations of Piroxicam 20 Mg: a Single-dose, Randomized-sequence, Open-label, Two-period Crossover Comparison in Healthy Mexican Adult Volunteers." Clinical Therapeutics, vol. 32, no. 2, 2010, pp. 357-64.
Palma-Aguirre JA, Lopez-Gamboa M, Cariño L, et al. Relative bioavailability of two oral formulations of piroxicam 20 mg: a single-dose, randomized-sequence, open-label, two-period crossover comparison in healthy Mexican adult volunteers. Clin Ther. 2010;32(2):357-64.
Palma-Aguirre, J. A., Lopez-Gamboa, M., Cariño, L., Burke-Fraga, V., & González-de la Parra, M. (2010). Relative bioavailability of two oral formulations of piroxicam 20 mg: a single-dose, randomized-sequence, open-label, two-period crossover comparison in healthy Mexican adult volunteers. Clinical Therapeutics, 32(2), 357-64. https://doi.org/10.1016/j.clinthera.2010.02.002
Palma-Aguirre JA, et al. Relative Bioavailability of Two Oral Formulations of Piroxicam 20 Mg: a Single-dose, Randomized-sequence, Open-label, Two-period Crossover Comparison in Healthy Mexican Adult Volunteers. Clin Ther. 2010;32(2):357-64. PubMed PMID: 20206793.
TY - JOUR T1 - Relative bioavailability of two oral formulations of piroxicam 20 mg: a single-dose, randomized-sequence, open-label, two-period crossover comparison in healthy Mexican adult volunteers. AU - Palma-Aguirre,Jose Antonio, AU - Lopez-Gamboa,Mireya, AU - Cariño,Lizbeth, AU - Burke-Fraga,Victoria, AU - González-de la Parra,Mario, PY - 2010/01/07/accepted PY - 2010/3/9/entrez PY - 2010/3/9/pubmed PY - 2010/5/29/medline SP - 357 EP - 64 JF - Clinical therapeutics JO - Clin Ther VL - 32 IS - 2 N2 - BACKGROUND: Piroxicam is an NSAID indicated for the treatment of rheumatoid diseases. Although there are generic formulations of oral piroxicam marketed in Mexico, a literature search did not identify published data concerning the bioavailability of these formulations in the Mexican population. OBJECTIVES: The aims of this study were to determine the bioequivalence of a generic (test) and a reference formulation of oral piroxicam 20 mg and to generate data regarding the oral bioavailability of this drug in a Mexican population. METHODS: This single-dose, randomized-sequence, open-label, 2-period crossover study was conducted in healthy Mexican adult volunteers. Subjects were randomly assigned to receive the test formulation followed by the reference formulation, or vice versa, with a 15-day washout period between doses. Study drugs were administered after a 10-hour overnight fast. For pharmacokinetic analysis, blood samples were drawn at 0 (baseline), 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 6, 8, 12, 24, 48, 72, 96, 120, and 168 hours after administration. Plasma concentrations of piroxicam were determined using HPLC. The test and reference formulations were to be considered bioequivalent if the 90% CIs for the geometric mean test/reference ratios were within a predetermined range of 80% to 125%. Tolerability was determined using clinical assessment, monitoring of vital signs, laboratory analysis, and subject interviews regarding adverse events (AEs). RESULTS: A total of 28 subjects were enrolled (15 men, 13 women; mean [SD] age, 24 [4] years [range, 19-35 years]; weight, 63.0 [8.9] kg [range, 47.5-81.9 kg]; height, 165 [10] cm [range, 149-179 cm]; and body mass index, 23.2 [1.4] kg/m(2) [range, 20.6-26.0 kg/m(2)]). The 90% CIs for piroxicam C(max), AUC(0-infinity), and AUC(0-infinity)) were 89.98% to 101.04%, 91.46% to 101.19%, and 93.51% to 105.86%, respectively. Thirteen subjects reported a total of 17 AEs during the study. None of the AEs were considered serious or related to the administered formulations. The most common AE was local postvenipuncture ecchymosis, reported in 8 subjects (28.6%). CONCLUSIONS: In this small study in healthy Mexican adult subjects, a single 20-mg dose of the test formulation of orally administered piroxicam met the regulatory requirements to assume bioequivalence, based on the rate and extent of absorption. Both formulations were well tolerated. Mexican national registry code: CE-PEC.0875. SN - 1879-114X UR - https://www.unboundmedicine.com/medline/citation/20206793/Relative_bioavailability_of_two_oral_formulations_of_piroxicam_20_mg:_a_single_dose_randomized_sequence_open_label_two_period_crossover_comparison_in_healthy_Mexican_adult_volunteers_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0149-2918(10)00053-6 DB - PRIME DP - Unbound Medicine ER -
Grapherence [↓1]
Administration, Oral
Anti-Inflammatory Agents, Non-Steroidal
Biological Availability
Chemistry, Pharmaceutical
Chromatography, High Pressure Liquid
Drugs, Generic
Therapeutic Equivalency
Bioavailability of two oral-tablet and two oral-suspension formulations of naproxen sodium/paracetamol (acetaminophen): single-dose, randomized, open-label, two-period crossover comparisons in healthy Mexican adult subjects.
Bioavailability of two oral formulations of a single dose of levofloxacin 500 mg: an open-label, randomized, two-period crossover comparison in healthy Mexican volunteers.
Bioavailability of two oral suspension and two oral tablet formulations of acyclovir 400 mg: two single-dose, open-label, randomized, two-period crossover comparisons in healthy Mexican adult subjects.
Bioavailability of two oral formulations of loratadine 20 mg with concomitant ketoconazole: an open-label, randomized, two-period crossover comparison in healthy Mexican adult volunteers.
Evaluation of the bioequivalence of single 100-mg doses of two oral formulations of cyclosporin A microemulsion: a randomized, open-label, two-period crossover study in healthy adult male Mexican volunteers.
Bioavailability of two oral formulations of azithromycin 500 mg: a randomized, open-label, two-period crossover comparison in healthy Mexican adult subjects.
Pharmacokinetics and bioequivalence study of three oral formulations of valsartan 160 mg: a single-dose, randomized, open-label, three-period crossover comparison in healthy Indian male volunteers.
Relative bioavailability and pharmacokinetic properties of two different enteric formulations of esomeprazole in healthy Bangladeshi male volunteers: An open-label, single-dose, randomized-sequence, two-way crossover study.
Bioavailability and bioequivalence of two oral formulations of alendronate sodium 70 mg: an open-label, randomized, two-period crossover comparison in healthy Korean adult male volunteers.
Bioavailability of two sublingual formulations of ketorolac tromethamine 30 mg: a randomized, open-label, single-dose, two-period crossover comparison in healthy Mexican adult volunteers.


text:
Q: PHP Minus/Subtract Hour/Minute strings formated H:i I have a PHP function that when given two values Hours/Minutes, it adds the two value, for example:

00:20 + 00:15 = 00:35

Here is the function:
function sumHoursAndMinutes() {
    $i = 0;
    foreach(func_get_args() as $time) {
        sscanf($time, '%d:%d', $hour, $min);
        $i += $hour * 60 + $min;
    }

    if( $h = floor($i / 60) ) {
        $i %= 60;
    }

    return sprintf('%02d:%02d', $h, $i);
}
// Usage: sumHoursAndMinutes("00:20", "00:15");

Output: "00:35"

How can I achieve the same thing doing subtraction, Example: 00:20 - 00:15 = 00:05

A: This might look like a long approach, but I'd personally just convert it into minutes. This makes it easier to handle and I used a reformat method for the following purpose: If your substractTimeFromTime or addTimeToTime returns something <0, you know, something was wrong with your inputs or it just doesn't make any sense in your context. Also, you need to verify that the times are valid, since 01:99 would be a valid input by now. I was just assuming you do the verification before.
function reformatMinutes($minutes)
{
    $hours = intval($minutes/60);
    $minutes -= $hours*60;
    return sprintf("%02d:%02d",$hours,$minutes);
}

function addTimeToTime($time1, $time2)
{
    $time1 = explode(":",$time1);
    $time2 = explode(":",$time2);
    $sumOfMinutes = intval($time1[0])*60+intval($time2[0])*60+intval($time1[1])+intval($time2[1]);
    return $sumOfMinutes;

}

function substractTimeFromTime($basis,$subtract)
{
    $basis = explode(":",$basis);
    $subtract = explode(":",$subtract);
    $remainingMinutes = intval($basis[0])*60-intval($subtract[0])*60+intval($basis[1])-intval($subtract[1]);
    return $remainingMinutes;
}

$resultPlus = addTimeToTime("01:10","00:15");
$resultMinus = substractTimeFromTime("01:30","00:15");
echo reformatMinutes($resultPlus);
echo reformatMinutes($resultMinus);

This outputs:
01:25
01:15

A: You can use date() and strtotime().
Remember to set the time zone back to your default again after.
We need UTC time zone to not have to worry about DST or time zone difference.
$a = "00:20";
$b = "00:15";

date_default_timezone_set("UTC");

echo date("H:i", strtotime($a) + strtotime($b));
echo "\n\n";
echo date("H:i", strtotime($a) - strtotime($b));

date_default_timezone_set("Your_default_timezone");

//00:35
//00:05

https://3v4l.org/kIVlI

If you need to calculate the hours and minutes manually from strtotime.
If it's addition you want to do you need to remove strtotime("00:00")*2 from the result because we are using Unix times.
Then I use str_pad to format the hours and minutes.
$a = "00:20";
$b = "02:15";

date_default_timezone_set("UTC");

// If addition
$diff = strtotime($a) + strtotime($b) - strtotime("00:00")*2;
$hours = floor($diff /3600);
$minutes = ($diff -($hours *3600))/60;

echo str_pad($hours,2,0, STR_PAD_LEFT) . ":" . str_pad($minutes,2,0, STR_PAD_LEFT) ;

echo "\n\n";

//If subtraction
$diff = strtotime($a) - strtotime($b);
$hours = floor($diff /3600);
$minutes = ($diff -($hours *3600))/60;

echo str_pad($hours,2,0, STR_PAD_LEFT) . ":" . str_pad($minutes,2,0, STR_PAD_LEFT) ;

//date_default_timezone_set("Your_default_timezone");

//02:35
//-2:05

A: Either write an almost identical function for minus instead of plus or add an optional Boolean parameter that defaults to plus but can be set to minus.


Your home is in the perfect location and came at the perfect price – yet you are thinking about making it "More Perfect". While any home improvement that brings you joy is priceless, not all projects create as much equity as you might expect.
This is especially true if you are thinking about selling in today's market. Let's get together to talk soon.
PreviousCyber Security – How Safe Are You?


English Calasancio: Do you consider important giving more power to students in schools?
People who really affect the development of the school and how it works are the students. But they are only children, not school headers.
On the one hand, students are those who are developing their brain, for in a nearly future, work in the development of this planet. For that reason, schools might help them to get them better their skills, and that is got with happiness. And at the same time, happiness is got by creating a place built, in some part, with their opinon.
On the other hand, students are children who are developing themselves, like I said before, and, for that reason, they are not able to take important decisions. It is good that students participate by giving their opinon of teachers and lessons, but important decision like to contract a teacher, must be taken by proffesional and formed people.
Definitely, the trick is that head teachers take decisions, but counting with the student's opinion.


text:
The Passing of a Music Giant
By JERRY TALLMER
Bobby Short dies after a lifelong career of singing America's songs
He was black and I am blue. "I'm white inside," the great song goes, "But that don't help my case, / 'Cause I can't hide / What is on my face… What did I do / To be so black and blue?"
And now Bobby Short is gone. Leukemia took him, Monday of this week, at New York Presbyterian Hospital. As the cliché goes, and for nobody was it ever truer, he was 80 years young.
"Guess who's in town!" is the way he would begin every show at the Carlyle this past decade or so, standing up at the piano, his hands hitting the keys, his voice detonating in joyous welcome. "I'se in town … We's in town!"—that meant him, his sidemen, all the people whose works he was singing—Razaf, Fats Waller, Cole Porter, the Gershwins, Harold Arlen, Vernon Duke, Duke Ellington, Irving Berlin, Johnny Mercer, the talent, the class—and the whole packed roomful of generally affluent, socially elect cabaret goers.
Somebody else who plays that room from time to time is a Dixieland saxophonist named Woody Allen. In a movie I love, Woody Allen's 1986 "Hannah and Her Sisters," there is a delicious incidental sequence when the Woody Allen character is thrown together with an even more neurotic, uptight individual, Hannah's sister Holly (Dianne Wiest). On their first date she takes him to a rock concert where the noise and the barbarism drive him nuts. When, out on the sidewalk, she asks him how he liked it, he says, well, maybe he'd prefer music by people who didn't look like they'd just murdered their grandmother. He takes her to the kind of music he likes—Bobby Short in full fettle at the Club Carlyle. She sits there, blank. Couldn't be more bored.
It is a very wicked scene, and it's what Bobby Short really is all about, or was—talent and class. In this moment of Western civilization when various black "artists" of the kind of noise that's called rap are in fact shooting one another, nothing could be clearer or more pointed. Way back when little Bobby Short, of Danville, Illinois, was a 10-year-old in a tuxedo—or was it white tie and tails?—on stage in Chicago as the "Miniature King of Swing," he knew what was good in music, and would always be, and what wasn't.
There was nothing prissy about Bobby Short. He had some very dear women friends, notably Gloria Vanderbilt, who was blackballed by the board of sacrosanct River House for fear that she would bring Bobby onto, or into, the premises; but even if he most likely never went to bed with a woman, he certainly knew where and what was the center of female sexuality, and gave it full appreciation in his rich rendition, as you've never heard it before, of the Razaf/Waller "Honeysuckle Rose," as well as Razaf's hilariously bawdy "If I Can't Sell It, I'll Keep Sittin' on It," a quadruple-entendre which is also often in the repertoire of rather large ladies like Ruth Brown.
With all the triumphs of his 70-year career, he was, I think, at the root, a lonely man, and I know from witnessing it that he was hardened to experiences like some drunk full of hostility talking loudly and vulgarly through one of his shows. Indeed, in several interviews I had with him over the years, he more and more indicated how fed up he was with the cabaret life, even if he was the king of cabarets. At every seasonal break he took off for his house in southern France, and stayed there until the new season began. But however fatigued he was, physically and spiritually, the one thing that Bobby Short radiated from the tiny stage (of sorts) at the Carlyle was Energy, capital E. He gave us his all—his relish, his joy, his appreciation, his preservation of the best of another kind of marriage, that of music and, yes, words.
He was always digging up rarities for us, or forgotten gems, and teaching us the history of things—shows, songs, events, lives, manners and mores. One night he started talking about Arthur Tracy, the Street Singer of pre-war radio, and he sang, in the Tracy manner, "The Street of Dreams," words and music by Victor Young and Samuel Lewis. I afterward told Bobby how deeply it had affected me, and on subsequent evenings he once or twice put it into the performance just for me. As I type out the words, I can hear it now, hear it in Bobby's soaring timbre:
Love laughs at a king
Kings don't mean a thing
On the street of dreams…
Gold, silver and gold
All you can hold
Is up there on a moonbeam
Poor, there ain't nobody poor
As long as love is sure
On the street of dreams.
… and I start crying. My wife Frances is not going to stop crying for quite a while.
Just now the phone rings. It is Maria, at the apartment of Betty Lee Hunt, Bobby Short's longtime publicist. The word has just come that "at Bobby's request, there will be no memorial services of any kind."
However, the Club Carlyle was dark tonight, Monday night, in his memory. Gold, silver and gold, all you can hold, all you can be—black and blue.


STRYME focuses on this year's HAMBURG OPEN fully on the market demand of social network for promt, easy-going & cost reduced production everywhere and anytime. Media attention shifted strongly to mobile and social networks. May it be news, entertainment or information. The broadcast industry is constantly changing. That's why we support everyone from media houses, broadcasters to semi-professionals and bloggers to transform and adapt to the audiences reality.
All it needs is a windows application producer controlling up to 4 cell phone cams (channels) in real time. Additionally, a chatting and instruction function is given. The IP based recordings are transferred into the cloud and shared immediately live on demand. No need for professional hardware nor requirement of special skills.
TUBICON LIVE will be demonstrated on STRYME booth 9.44 at this year's Hamburg Open, tomorrow January, 17th 2019.
Flexible 4x4K UHD in a 2U GENESIX VideoServer supporting SONY XAVC codec.
A simple & easy way of renting GENESIX, a high-tech all-in-one multi-channel 2U video server, for any professional productions. Including: applications, support, configuration and installation.
Visit our booth 9.44 (A9/10) at Hamburg Open 2019 and receive valuable benefits and insights from our solution specialists. Above all, learn more about STRYME's latest innovation and developments.


EUDML | Statistical manifolds with maximal automorphisms group. EuDML | Statistical manifolds with maximal automorphisms group.
Statistical manifolds with maximal automorphisms group.
Sebe, Gabriela Ileana. "Statistical manifolds with maximal automorphisms group.." APPS. Applied Sciences 2.1 (2000): 23-32. <http://eudml.org/doc/227226>.
TI - Statistical manifolds with maximal automorphisms group.


text:
Hainan Airlines Announces New Flights to Mexico
February 3, 2018 Jace Moseley Top Story
A Hainan Boeing 787-9 departs Boston (Photo: AirlineGeeks.com | Ian McMurty)
China's Hainan Airlines has announced flights from Beijing to Mexico City, with a technical stop in Tijuana, beginning on March 21, 2018.
The flight will operate three times weekly and be serviced by the Boeing 787 Dreamliner aircraft, the airline's aircraft of choice for long ranges flights to North America due to its low operating costs and fuel efficiency. The airline sought service to Mexico in 2016 but plans never come to fruition. The airline reapplied to the Civil Aviation Authority of China (CAAC) for authorization to Mexico in 2017, along with Tehran, Zurich and Sydney.
According to Forbes Mexico, up to 120,000 Chinese tourists visited Mexico in 2017, an increase of 14 percent from 2016. Jose Luis Bernal, Mexico's ambassador to China, said, "We are sure that the attraction that Mexico City has for its connectivity to different points in Mexico and other places in Latin America, and even North America and Europe, will have a very important effect on the growth of tourism."
Tijuana is considered to be a classic stopover point for flights to Asia from Mexico as it located at sea-level and is nearly 1,400 miles closer to Asia than Mexico's capital, allowing for more reasonable "non-stop" flight to inland locations in Asia.
The route is similar to the Mexico City-Tijuana-Tokyo flight that AeroMexico served historically until recently. The technical stop in Tijuana is necessary in part due to the elevation of Mexico City, reducing the capability of aircraft and requiring a fuel stop in the Mexican border town. Located within feet of the United States/Mexico international border, the airport is farthest north the Mexican airline can fly within Mexico to refuel.
After 2014, AeroMexico's Tokyo flight started making stopovers in Monterey instead of Tijuana as Tijuana International Airport improved their runways. The flight never returned to Tijuana, as AeroMexico's Dreamliner was able to make the trip without the stop. However, AeroMexico does maintain a Mexico City-Tijuana-Shanghai with its Dreamliner.
It is currently unknown whether Hainan will be able to sell seats between Tijuana and Mexico City or Tijuana and Beijing. However, if the airline is allowed to sell tickets to Tijuana, it can be an additional option for travelers to and from San Diego and the U.S. side of the border region, using the new Cross Border Xpress at Tijuana Airport.
The Cross Border Xpress takes advantage of Tijuana Airport's location just feet away from the international border. Upon landing in Mexico, international passengers clear Mexican customs, then walk across the bridge into the United States, without leaving the terminal, where they will clear U.S. customs and immigration.
For those departing from Tijuana, you can walk across the bridge from the U.S., clear Mexican customs and board any flight. Most airlines maintain check-in desks on the U.S. side of the terminal but checked baggage, however, will be dropped off on the Mexican side of the border after clearing Mexican customs. Wait times are limited as the bridge is only open to airport customers and crossing is subject to a fee.
Since San Diego International Airport only has one nonstop flight to Asia with Japan Airlines' flight to Tokyo, the Cross Border Xpress is a way for Americans to have access to more international flights from Tijuana, without having to step foot in Mexico, for all intents and purposes, outside of Tijuana Airport. While passengers will have to add an extra trip to customs on both ends of their journies, it will save time as they can fly nonstop to their destinations.
If Hainan Airlines is able to sell tickets to Tijuana, they can market San Diego/Southern California as a destination, in addition to Tijuana, as the Cross Border Express and other border crossings near the airport make the United States easily accessible from the airport without restrictions on the airline as the plane itself will not be entering the U.S. , and Mexico City. With two flights, Hainan has the potential to serve three markets.
This story was corrected on Feb. 3, 2018 at 8:40 p.m. ET to remove an error stating that Hainan is the first Chinese airline to connect China and Mexico. This is not true as China Southern operates a route between the two nations.
Jace Moseley
Jace has been working at AirlineGeeks for nearly three years. Born in Seattle, Boeing and aviation quickly took over his life and he never stopped looking up. Jace enjoys plane spotting and taking trips just so he can fly. He is currently studying at Embry-Riddle Aeronautical University while earning his Bachelors of Science in Air Traffic Management.
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text:
End Game: When Leicester inflicted Liverpool's first home defeat in 85 games
Leicester City ended Liverpool's run of three years and 63 home league games without defeat at Anfield in 1981.
20th November 2020 | Retro, Premier League, Football Matthew Crist
In January of 1981, Bob Paisley's Liverpool were 85 matches unbeaten in all competitions at Anfield, before eventually succumbing to relegation-threatened Leicester City in one of the shocks of the decade.
It was a run that comprised 63 league matches without defeat, along with six in the FA Cup, nine in the League Cup, six in the European Cup, and one in the European Super Cup.
Paisley's Liverpool were the league champions and that season's European Cup winners, who had been utterly dominant at home and abroad.
Much of this success was built on an incredibly tight defence, who famously only conceded four goals in 21 home league matches in the 1978/79 season as they beat Brian Clough's Nottingham Forest to the title.
In retaining the First Division league championship the following season they conceded a measly eight goals at Anfield and just 16 in total.
But for all their defensive prowess, Paisley's Liverpool side had a ruthless streak in front of goal too putting their opponents to the sword whenever they smelt blood.
On their way to winning the title in 1979, they hammered Derby 5-0, thrashed Norwich 6-0 and beat Tottenham 7-0 in one of the most famous Anfield demolitions of the decade.
So when Leicester City arrived at Anfield on January 31, 1981, few would have foreseen anything other than another home victory.
Jock Wallace's team were anchored at the foot of the old First Division, having lost their last five league games without even scoring a goal.
To make matters worse, The Foxes had also just been knocked out of the FA Cup after a 3-1 defeat to Third Division Exeter City.
This was all a far cry from Wallace's confident prediction at the start of the season that his young side would win the Old First Division title
Liverpool, on the other hand, were going for a three-peat having won the league in the two previous campaigns, not to mention the European Cup in 1977 and 1978.
And six wins from their opening ten games would provide Reds fans with optimism, though the defending champions did taste their first defeat of the campaign away at Leicester of all places on August 23, going down 2-0 at Filbert Street.
But a run of five consecutive draws in November would derail their title bid somewhat while a number of key injuries over Christmas would also take its toll on Paisley's squad.
Alan Kennedy, Alan Hansen, David Fairclough and Kenny Dalglish were all on the sidelines ahead of Leicester's visit, with Avi Cohen, Colin Irwin and the veteran Steve Heighway called-in to deputise.
Even so, Liverpool began the game third in the league, two points behind both Ipswich and Aston Villa, knowing that another home win would keep them in touch at the top.
Normal service looked to have been established when the unfortunate Alan Young headed past keeper Mark Wallington after just 15 minutes as a 64th game unbeaten at home looked a certainty.
Liverpool piled forward at every opportunity with Leicester doing their best not to buckle under the relentless pressure as the Reds missed chance-after-chance, but managed to make it to the break only one goal down.
Incredibly, the second period saw something of a transformation with the Foxes taking the game to their hosts as Ray Clemence, who had been something of a spectator in the first-half was called into action on a number of occasions.
An uncharacteristic error from the legendary 'keeper would give Leicester a lifeline when he fumbled a cross at the feet of Pat Byrne, who rolled the ball into an empty net.
"Clemence was coming out. I clattered him. The ref didn't give a foul and Paddy Byrne put it in," Alan Young would reveal after the game.
Buoyed by their unexpected equalizer, the visitors seized their chance and with 15 minutes remaining Jim Melrose, who was in his first season at the club, took a pass from Alan Young, and fired in a 20-yard drive which left Clemence wrong- footed and the Kop stunned.
Liverpool were unable to respond and at the final whistle, the Leicester players celebrated an unlikely league double – the first club to do so over Liverpool since Arsenal achieved the feat in the 1974/75
As the players left the field the home crowd sportingly acknowledged their efforts while also applauding their heroes who had not tasted a home league defeat for three years.
"Our defeat was a good example of complacency," said Paisley afterwards. "I only hope it gets through to our players that in football there are no certainties, only uncertainties."
The following week, Liverpool lost again, this time at West Brom leaving Aston Villa and Ipswich to fight it out for the league as a third consecutive title bid fizzled out.
They would finish fifth in the league, though would lift the League Cup as well as sealing a third European Cup victory by beating Real Madrid in Paris.
As for Leicester, they followed-up this famous win a week later with victory over Manchester United and there were other notable victories against Tottenham Hotspur and Arsenal, but these were not enough for Leicester to avoid relegation.
Nevertheless, that win in January of 1981 which ended Liverpool's 85-match run of undefeated home games, was a truly remarkable achievement that still lives in the memory of Foxes fans all these years on.


On Day 3, we've decided to feature the wonderful Felice Brothers with a beautiful live version of their track 'Dream On', live from Pickathon 2013. This close-knit group consists of brothers Ian and James Felice, alongside friends Joshua, Greg and Dave. Starting from roots of busking in NYC's subway stations, to recently touring with the likes of Mumford and Sons and The Killers, we couldn't think of a better example of what pays off when you work hard. Plus, their new album 'Favourite Waitress' is set for release next week on June 17th 2014, so make sure you pick up a copy of what is destined to be another killer record. The Felice Brothers play Bush Hall @ 22:00, but until then, check out their live rendition of 'Dream On'.


Heart failure and arrhythmias occur at 3 to 5 times higher rates among individuals with diabetes mellitus, compared with age-matched, healthy individuals. Studies attribute these defects in part to alterations in the function of cardiac type 2 ryanodine receptors (RyR2s), the principal Ca2+-release channels on the internal sarcoplasmic reticulum (SR). To date, mechanisms underlying RyR2 dysregulation in diabetes remain poorly defined. A rat model of type 1 diabetes, in combination with echocardiography, in vivo and ex vivo hemodynamic studies, confocal microscopy, Western blotting, mass spectrometry, site-directed mutagenesis, and [3H]ryanodine binding, lipid bilayer, and transfection assays, was used to determine whether post-translational modification by reactive carbonyl species (RCS) represented a contributing cause. After 8 weeks of diabetes, spontaneous Ca2+ release in ventricular myocytes increased ∼5-fold. Evoked Ca2+ release from the SR was nonuniform (dyssynchronous). Total RyR2 protein levels remained unchanged, but the ability to bind the Ca2+-dependent ligand [3H]ryanodine was significantly reduced. Western blotting and mass spectrometry revealed RCS adducts on select basic residues. Mutation of residues to delineate the physiochemical impact of carbonylation yielded channels with enhanced or reduced cytoplasmic Ca2+ responsiveness. The prototype RCS methylglyoxal increased and then decreased the RyR2 open probability. Methylglyoxal also increased spontaneous Ca2+ release and induced Ca2+ waves in healthy myocytes. Treatment of diabetic rats with RCS scavengers normalized spontaneous and evoked Ca2+ release from the SR, reduced carbonylation of RyR2s, and increased binding of [3H]ryanodine to RyR2s. From these data, we conclude that post-translational modification by RCS contributes to the heterogeneity in RyR2 activity that is seen in experimental diabetes.


text:
Le capsomère est une sous-unité de la capside d'un virus, un revêtement extérieur de protéines dont le rôle est de protéger le matériel génétique. Les capsomères s'auto-assemblent pour former la capside. Ils sont eux-mêmes composés de protomères.

Formes
Les capsomères peuvent s'assembler de trois façons différentes pour former la capside: icosaédrique, hélicoïdale ou mixte (symétrie icosaédrique et hélicoïdale à la fois).

Notes et références

Virologie


Latin Grammy 2018: is this the end of the empire of the reggaeton?
Find out the sound that comes is a task intricate and reckless for a large group of musicians. "I have not the most remote idea, released at the first change, Jorge Drexler. "I don't care, the truth," replies Draco Rosa with disdain, the former of Often. But one of the voices of Latin american that are willing to risk to give a forecast there is some inclination towards a return to the origins. The relay to the gender, urban and reggaeton, they say, will come out of folklore and the return to the roots. Modernity and ancient culture in the same shaker to give birth to the next genre that imposes its law.
count It from the right place, the annual celebration's most important Latin american music, Latin Grammy awards, which this year celebrates 19 editions in your seat habitual, Las Vegas. A gala in which, by the way, the main nominee will be a standard-bearer of reggaeton and urban music, the colombian J. Balvin. The Medellin seeks, among other things, to be done with the awards for album of the year, record of the year (double nomination), best fusion / interpretation urban, best urban music album and best urban song (triple nomination).
from behind will be the five nominations of Rosalia, the phenomenon Catalan of the new flamenco, and a wide representation of spain, with two nominations for Rozalén and Pablo Alborán, Vetusta Morla, Bunbury and Manolo García.
But beyond the trend that make the nominations, and Visitor, the former of Calle 13 and one of the great exponents of the genre urban, feels that the range of what comes next is much more inclusive. "In America it takes the diversity," explains to THE WORLD from the red carpet at the tribute to Manna of the Latin Recording Academy. "I'm a fan of diversity, and I am not an uncompromising defender of the genre urban. Mine is also diverse, the disk of Calle 13, are disks eclectic. Look at discs as the last of Café Tacvba, a memorable one. That is the way."
Catalina García, lead singer of one of the new phenomena in Colombia, Monsieur Perineum, it goes up to the train Visitors. "Latin america turns to need artists who are capable of seeding positive messages, affirming their roots, especially in times of so much oppression and people being retrograde in power".
La Marisoul, voice and passion of the group chicano La Santa Cecilia, born in Los Angeles, with eyes always set on the other side of the border, props up the feel of your colleagues. "Some artists are rediscovering the folklore of Latin america, always a source of inspiration," he says with passion in the voice. "It's blending the music of root, and that can give us wings to experiment and give birth to new things. New genres will come out of there."
the vote of The other side of the pond comes from Jorge González, drummer of Vetusta Morla. "Here there are less labels and borders, folk music is connecting with the rock and the electronics, and that is something that is noticed and perceived". And that only takes a few hours in Las Vegas.


text:
Engelthal Abbey or St. Mary's Abbey, Engelthal, is a Benedictine nunnery in the Wetterau region, Hesse, Germany.

Engelthal Abbey was a Cistercian nunnery from its foundation in 1268, until the secularisation of 1803. It was ruled by Imperial Counts of Leiningen-Westerburg-Neuleiningen and later in 19th century sold to Counts of Solms-Wildenfels.

In 1962 it was re-settled by the Benedictine nuns of Herstelle Abbey. The house was raised to the status of abbey in 1965, and belongs to the Beuronese Congregation of the Benedictine Confederation.

Besides the normal Benedictine duty of hospitality, the nuns of Engelthal are also involved in the restoration of ecclesiastical works of art.

Sources and external links
 Abbey Website

Cistercian nunneries in Germany
Monasteries in Hesse
1260s establishments in the Holy Roman Empire
1268 establishments in Europe
Religious organizations established in the 1260s
Benedictine nunneries in Germany


text:
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(collectively, the "Acceptable Use Policy").
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4 OWNERSHIP RIGHTS
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4.4 You may have access to Third Party Content through use of the Services. Unless otherwise expressly stated, all ownership and intellectual property rights in and to Third Party Content and the use of such content shall be governed by separate terms and conditions between you and the third party.
5 CONFIDENTIALITY AND PRIVACY
5.1 Any information identified by you or iShine Cloud in writing as confidential ("Confidential Information") may be used only in connection with the Proposal and for the purposes for which the Confidential Information was disclosed. You agree to protect the confidentiality of the Confidential Information in the same manner that you protect the confidentiality of your own proprietary and confidential information of like kind; and exercise reasonable care in protecting such Confidential Information.
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6 WARRANTIES
6.1 We warrant that during the Service Period, services performed by iShine Cloud will be performed using commercially reasonable care and skill in all material respects ("Warranty").
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9.1 Subject to clause 7.1 above, each Party ("Indemnifying Party") agrees to indemnify the other Party ("Other Party") if a third party makes a claim ("Claim") against the Other Party that any information, design, specification, instruction, software, service, data, hardware, or material (collectively, "Material") used by the Other Party, infringes the third party's intellectual property rights, in the event that such Material was furnished to the Other Party by the Indemnifying Party. The Indemnifying Party, at his sole cost and expense, will defend the Other Party against the Claim, and indemnify the Other Party from all damages, liabilities, costs and expenses awarded by the court to the third party claiming infringement, or as agreed by way of a settlement with the third party, PROVIDED THAT the Other Party does the following:
(a) notifies the Indemnifying Party promptly in writing, not later than 30 days after the Other Party receives notice of the Claim (or sooner if required by applicable law);
(b) gives the Indemnifying Party sole control of the defence and any settlement negotiations; and
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9.4 The Indemnifying Party will not be liable to indemnify the Other Party if the Other Party:
(a) alters the Material or uses it outside the Purpose or otherwise uses it in violation of the terms of this Agreement; or
(b) uses a version of the Material which has been superseded, if the infringement claim could have been avoided by using an unaltered current version of the Material which was made available to the Other Party.
9.5 The Indemnifying Party will not indemnify the Other Party to the extent that an infringement claim is based upon any Material not furnished by the Indemnifying Party.
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10 TERMINATION
10.1 We may terminate any or all of the Services with immediate effect where you :
(a) have committed a material breach that is not capable of remedy;
(b) have committed a breach of these Terms which is capable of remedy, but fail to correct the breach within [30] days of written notification of the breach. Except for non-payment of fees, we may agree in our sole discretion to extend the 30-day period for so long as you continue to make reasonable efforts to cure the breach;
(c) have gone into liquidation whether compulsorily or voluntarily (except for the purpose of a bona fide reconstruction or amalgamation).
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12 FORCE MAJEURE
12.1 iShine Cloud shall not be responsible for failure or delay of performance if caused by a Force Majeure event. However, iShine Cloud will use reasonable efforts to mitigate the effect of a Force Majeure event. If such event continues for more than 30 days, you may terminate the Services upon written notice. This Clause does not excuse you from your obligation to pay for the Services up to the date of termination.
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13.2 We may give notices applicable to our Services by means of a general notice within messaging services within the Services, and notices specific to you by electronic mail to your e-mail address on record in our account information or by written communication sent by post to your address on record in our account information.
14.1 You may not assign or transfer the User Subscriptions, or any interest in the Services, to another individual or entity.
15 GENERAL
15.1 Our business partners and other third parties, including the Technology Providers and any third parties with which the Services have integrations or that are retained by you to provide consulting services, implementation services or applications that interact with the Services, are independent of iShine Cloud and are not iShine Cloud's agents. We are not liable for, bound by, or responsible for any problems with the Services or Customer Content arising due to any acts of any such business partner or third party, unless the business partner or third party is providing Services as our subcontractor on an engagement ordered by iShine Cloud, in which case we would be responsible only to the extent of our obligations under these Terms.
15.2 If any of these Terms are found to be invalid or unenforceable, the remaining provisions will remain effective and such Terms shall be replaced with another Term consistent with the purpose and intent of these Terms.
15.3 Prior to accepting our Proposal, you are solely responsible for determining whether the Proposal is suitable for your purpose, though we will provide our assistance and co-operation in relation to your efforts to determine such suitability. Additional fees may apply to any additional work performed by iShine Cloud or changes to the Services. You remain solely responsible for your regulatory compliance in connection with your use of the Services.
15.4 Upon twenty-one (21) days' written notice and no more than once every twelve (12) months, iShine Cloud may audit your compliance with these Terms. In the event, you agree to co-operate with iShine Cloud's audit team and to provide reasonable assistance and access to information. iShine Cloud shall use reasonable efforts to ensure that the audit will not unreasonably interfere with your normal operations.
15.5 This Agreement does not create any agency, partnership or joint venture.
15.6 This Agreement does not confer any rights on any person or party (other than the parties to this Agreement and, where applicable, their successors and permitted assigns) pursuant to the Contracts (Rights of Third Parties) Act of Singapore (Cap. 53B Rev Ed, 2002).
16 GOVERNING LAW AND JURISDICTION
16.1 This Agreement shall be governed by and construed in accordance with the laws of the Republic of Singapore. Any dispute arising out of or in connection with this Agreement, including any question regarding its existence, validity or termination, shall be referred to and finally resolved by arbitration in Singapore in accordance with the Arbitration Rules of the Singapore International Arbitration Centre ("SIAC Rules") for the time being in force, which rules are deemed to be incorporated by reference in this clause.
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17.1 You agree that this is the complete Agreement for the Services ordered by you and supersedes all prior or contemporaneous agreements or representations, written or oral, regarding such Services.
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This week at Experia, we are taking a look at some of the most innovative and interesting types of support available to help those with dementia.
Compiling a 'My Life' story is something that people with dementia, family members and professional carers can benefit from. Due to problems with memory loss or communication, people with dementia sometimes need help to communicate their 'story' (those important aspects of their identity like background, interests, who and what is important to them).
This entry was posted in General, dementia, sensory solutions, 5 Creative Support Tools for Dementia and tagged sensory, sensory equipment experts, sensory solutions, dementia, dementia awareness week, alzheimers, alzheimers society, Experia, dementia awareness, dementia support, sensory solutions dementia, Alzheimers Research, dementiabarber, dementiatraincarriage, dementiadolls, dementiadolltherapy, sensorycart, dementiacart, experiadementiacart, dementiamylifestory, mylifestory on July 31, 2017 by Victoria Reddington.
This week is Dementia Awareness Week. Spearheaded by Alzheimer's Society, Dementia Awareness Week is dedicated to raising the profile of the condition in the public eye. Throughout this week there will be national and regional press coverage, awareness-raising and fundraising events across England, Wales and Northern Ireland. The focus of this year's campaign is uniting together against dementia to improve care, offer help and understanding and give everyone the help they need.
This entry was posted in dementia and tagged sensory, bubble tube, sensory equipment experts, dementia, dementia awareness week, alzheimers, alzheimers society, fundraising on May 15, 2017 by Victoria Reddington.


Angela Ferguson has been announced as the new Managing Director of futurespace.
Currently the National Association of Women in Construction (NAWIC) Businesswoman of the Year, Ms Ferguson has been a director and owner of futurespace since October 2009 when she merged her own successful practice (Ferguson Design Studio) with that of futurespace.
Over the last three years Ms Ferguson has established her role in the business and has played an instrumental role in the organization's success. Ms Ferguson brings to the position her holistic approach to business and her experience of working in the construction industry for the last 20 years. With a background in interior design and project co-ordination Ms Ferguson has extensive experience in the Australian market working with a diverse mix of clients.
In addition to giving mant peer industry talks, Ms Ferguson has tutored in design and written extensively on design issues for the local and international architectural press.
"futurespace is a renowned practice and has accomplished a huge amount since its establishment in 2001. I am looking forward to driving the next evolution of futurespace and to working with the team to evolve into new markets and industry sectors" Ms Ferguson said.
Owner and outgoing Managing Director Stephen Minnett strongly supports the restructure. "This is a fantastic opportunity to realize the potential of the business and to acknowledge Angela's leadership expertise. We will spend the next 100 or so days going through an onboarding process with a new way forward ready for implementation on 1 July" explains Mr Minnett.


Right then here are some pics of my engine minus the EGR and the bits I took off.
EGR valve removed from exhaust manifold.
EGR solenoid with pipe work removed but still connected electrically positioned on nearside inner wing by the air intake part of which is removed to take the photo.
The bits that were removed.
editted to add the following.
just remembered that i blanked off the vacuum feed to the solenoid at the tee on the bulkhead (sorry no picture of that).
Going back to the post by BogMonster on the previous page, I am intrigued by the ftment og an EGT probe refered to in the posts from last year. I note that a few regulars have these fitted and wonder what I would need to buy and where to get it in order to fit one to my 200 tdi disco. I have full set of tap and dies.
I have tweeked the pump a little bit and upped the turbo boost (again only a bit) but have noticed recently, especially when towing up long hills that the engine "smells" hot. The temp gauge rarely goes above halfway (when I remember to turn on the leccie fan!).
im sure ive seen a thread on fitting EGTs mark. damned if i can find it though, maybe someone else will be able to?
I found the post in the tech Archive earlier. Was in fact the same one as was refered to in this thread! But where does one actually buy the stuff from to make one. i found somewhere selling the probes but not the digital read-outs. Any one?
Thermoman for me too - a complete kit everything you need to fit it except a number plate fixer which I used to attach the display.
Location:Wherever work is in summer, Stirlingshire, Skeggy and then Thailand in winter!
We also remove EGR from TD5s. Remove the pipe thingy that runs around the front of the engine, fit a blanking plate (home-made) to the exhaust manifold, push a ball-bearing down the vacuum (or whatever) connection and unplug the electrics. The ECU is quite happy after this. But, like Steve in the Falklands, we don't have to worry about emission tests as there are no rules here either. And no MOT test, which is a good thing or a bad thing depending on your point of view.
We remove the pipe and fit a blanking plate because the pipes have a history of breaking off under the EGR valve. The pipe doesn't break, but the alloy connection into the EGR valve does. This causes major havoc with the exhaust gases melting the plastic cover and electrical wiring etc.
I make the blanking plates using an angle grinder and a drill. We have been meaning to have some laser cut.
I'm glad to see that it makes little or no effect to the emissions.
Interesting ... I've never seen that here but I can see it would get a bit warm under there!
After following the thread , i decided to replace my brother 300's EGR valve and fit one of those thermo guages. ordered it from Thermo man too. took some 6 days to travel from Down under to the island of Malta.
The digital guage looks great during night driving !!!!
thanks for the very detailed topic.
I also have some pics to add to the ones you have about the dashboard fitting and wire routing , but here ISP connection is slow so it will take me some time to put them up.
I have had an egr removal kit on my TD5 for about 1 year now, this consists of a blanking plate for the ex manifold and a flange and pipe assy to replace the egr valve complete, been trouble free as it should be no moving parts etc!
i have just unplugged mine - as I believe the solenoid is failed shut without power, so havent gone to the hassle of removing it unless someone knows otherwise.
I would think that'll only work if your EGR valve hasn't failed yet? They seem to jam open rather than shut.
wallet is getting worried with all the extra mods to come.
Buy one from a dealer - it won't be that expensive. You just need to ask for a hose from intercooler to inlet manifold for a non EGR engine.
If you want silicon call Allisport .. thats where i got mine ..
I found that the standard Intercooler to Inlet minus EGR branch is around £6-7 and I'm about to send a mail to Allisport.
standard one is perfectly ok and far cheaper.
make sure you seal the tube that went to the large bore tube work from the airbox to the turbo around the basck of the engine as this is after the airfilter and any water getting in there is non stop to the engine.
I removed the entire set up wiring everything.
Just come back from Landranger in Stockport with the bits I need.