text:
Home Industry Community pharmacy effective in reducing prescribing waste
Community pharmacy effective in reducing prescribing waste
An English project looking to reduce medicines wastage across community pharmacy, care homes and general practice has produced savings representing a return of nearly £4.28 on every £1 spent on its development.1
'Community pharmacy teams are in the unique position of interacting with the patient each time they dispense a prescription, so they frequently have the opportunity to discuss medication regimens with the patient and identify opportunities for medicines optimisation,' report author Richard Brown said.
Clinical commissioning groups (CCGs), similar to Primary Health Networks in Australia, are local organisations led by clinicians including general practitioners, set up to organise the delivery of healthcare at the primary level and influence commissioning decisions for their patients.
When it was revealed that dispensing volumes in the country had increased by 18% in the years 2010 to 2016,2 one particular CCG identified this issue as an opportunity to be tackled by community pharmacy.
The joint project between Avon Local Pharmaceutical Committee and Bath and North East Somerset (BaNES) CCG evolved into a medicines optimisation strategy through remunerating pharmacies in the identification of unwanted medicines. Unlike previous 'not dispensed' schemes in the UK, the pilot aimed to address the surgery medication record, identified as the 'main cause of the problem'.1
Using an electronic practice support platform, community pharmacies were able to raise issues with practice support pharmacists in GP practices of medications no longer required by the patient, or cases where the treatment could be optimised to reduce cost.
Once the practice support pharmacist approved the changes, the reimbursement was processed to the community pharmacy. A professional fee of £30 was paid to the community pharmacy along with the reduction in fees and the retained margin caused by not dispensing the item.
This way of working provided the CCG with a level of financial governance because, unlike most schemes of this nature,3,4 the CCG only reimbursed the community pharmacy once they had realised the saving.
The initial pilot began with 5 community pharmacies over an 8-week pilot phase, the program was then expanded to include a further 11 pharmacies, placing emphasis on high-value changes, wastage within care homes and improving communication between the community pharmacist and practice support pharmacist.
'What started off as a project to stop medication waste has already evolved into a medicines optimisation strategy in which community pharmacists are now actively looking for patients who are not on the most effective treatment regimen according to local treatment protocols or national guidance,' Mr Brown said.
'By harnessing a community pharmacist's extensive medication knowledge and patient contact time, this project puts them at the forefront of community-based medicines optimisation and presents a novel way for CCGs to work with their community pharmacy colleagues.'
1. Trueman P, et al. Evaluation of the scale, causes and costs of waste medicines. Report of a DH funded national project. York Health Economics Consortium and the School of Pharmacy, University of London. 2010. At: http://discovery.ucl.ac.uk/1350234/.
2. Brown, R. Reducing prescribing waste. Prescriber. 2018:35-38.
3. Gloucestershire Local Pharmaceutical Committee. Not Dispensed Scheme. At: http://psnc.org.uk/gloucestershire-lpc/services/not-dispensed-scheme-2/.
4. NHS Coventry. Enhanced 'not dispensed' scheme. March 2010. At: http://www.coventrylpc.co.uk/wp-content/uploads/2017/02/ND-GUIDANCE-Rev-Mar-2010.pdf.
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Chitral DC office to have video link facility
CHITRAL: A videoconferencing system is being put in place in the office of the deputy commissioner here to spare heads of various government departments in Chitral from frequently travelling to Peshawar for official meetings.
?Confirming the development on Wednesday, Chitral Deputy Commissioner Irshad Sodhar told Dawn that in line with the directives of the chief secretary, arrangements had been made to provide the facility of videoconferencing in his office so that heads of government departments could be saved from travel to the provincial headquarters for meetings.
He said he had observed soon after his posting in Chitral two months ago that the heads of departments left for Peshawar every month making the meetings in the secretariat or directorate merely an excuse while their attendance there was not necessary at all.
Mr Sodhar said the video link would decrease the frequency of travel of the officers by 80 per cent and they would go there only when it was extremely necessary and unavoidable.
He said he had made it mandatory for the officers to seek permission from his office before leaving the station.
Officials in different government departments, however, confided to Dawn that the officers were still defying the orders of the DC and left the station stealthily, but they did rush back as early as possible to escape his wrath.
They said in the past the officers left the station two days earlier than the scheduled date of meeting and returned the next week as most of them were non-locals and visited their respective villages, and all this was done on government?s expense.
Published in Dawn, November 16th, 2017
One thought on "Chitral DC office to have video link facility"
Wg Cdr (r) Fardad Ali Shah says:
Excellent step. This is the kind of reforms we need to improve governance. Technology must be used to eliminate wastage of time and resources and alleviate the troubles of the people. Well done CS, KP.

redpajama_set_name: RedPajamaCommonCrawl


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Orpheus, original title Orphée, is a stage play written by Jean Cocteau, produced in Paris 1926 by Georges Pitoëff and Ludmilla Pitoëff, with decors by Jean Hugo and costumes by Coco Chanel.

The play was the first major work for the theater written by Cocteau. It is based on the myth of Orpheus, dealing largely with the supernatural. While contemporary critics called the work "superficial," it has later been called "a brilliantly conceived homage to the supernatural". Cocteau later adapted the play to the better known film Orpheus (1950).

Plot
The scene is Orpheus and Eurydice's home in Thrace. There is a mirror on the left wall and at stage rear a white horse, protruding from a niche. As the play begins Orpheus is trying to interpret a message that the horse is tapping out with his hoof. Eurydice expresses her jealousy for the supernatural nag who takes so much of her husband's time. Orpheus angrily replies that the horse brings him phrases from the unknown that are more astonishing than all the poems in the world. The poem the horse taps out for Orpheus reads "Madame Eurydice Reviendra Des Enfers" ("Madam Eurydice Will Come Back From Hell"). Orpheus enters the poem in a contest but the judges are infuriated because the initial letters of the words spell "MERDE" ().

While Orpheus is at the contest Eurydice is murdered by her ex-friends, the Bacchantes. Returning, Orpheus decides to rescue her from death. Instructed by the angel Heurtebise, he passes through the mirror and brings Eurydice back to life, but life together is impossible as he is not allowed to look at her. The Bacchantes return to harass Orpheus, claiming he has submitted an obscene poem. Orpheus is decapitated and Eurydice leads him back through the mirror. The angel puts Orpheus's head on a pedestal, where, in answers to questions from the police, it announces it is Jean Cocteau and gives Cocteau's address, 10 rue d'Anjou.

References
Neal Oxenhandler "The Theater of Jean Cocteau," Jean Cocteau and the French Scene, Abbeville Press 1984

Plays by Jean Cocteau
1926 plays

redpajama_set_name: RedPajamaWikipedia


text:
, also known as Mikohidari Tadaie, was a Japanese statesman, courtier, politician, poet and calligrapher during the Heian period.

In 1090 he ordained as a Buddhist monk and undertook the precepts a year later. He died several months later.

Career at court
He was a minister during the reigns of Emperor Go-Reizei, Emperor Shirakawa and Emperor Horikawa.

Tadaie did well at court, rising to the Senior Second Rank and the office of Dainagon (Major Counselor).

Poet
In this period of Japanese history, the duties of Imperial courtiers included an expectation that each would create and present poems.

An incident from Tadaie's life is featured in a poem which captured a fleeting moment and a gallant gesture:

Calligrapher
Examples of calligraphy attributable to Tadaie are identified variously by the Japanese government as a "National Treasure", as an "Important Art Object" and as an "Important Cultural Property".

Genealogy
Tadaie's grandfather was Fujiwara no Michinaga; and his father was Fujiwara no Nagaie.  The son of Tadaie was Fujiwara no Toshitada (1071–1123). This lineage was identified as the Mikohidari lineage within the Hokke branch of the Fujiwara clan.

Tadaie was the grandfather of the poet Fujiwara no Toshinari (1114–1204), who was also known as Shunzei. Tadaie was the great-grandfather of Fujiwara no Sadaie, also known as Fujiwara no Teika.

Notes

References
 Porter, William N. (1909). A Hundred Verses from Old Japan, Being a Translation of the Hyaku-nin-isshiu. Oxford: Oxford University Press.
 Sato, Hiroaki. (2008). Japanese Women Poets: an Anthology.  Armonk, New York: M.E. Sharpe.;

1033 births
1091 deaths
Fujiwara clan
People of Heian-period Japan
Heian period Buddhist clergy


Great 1 bedroom, 1 bath condo featuring newer heater A/C and water heater. Huge bedroom. Wonderful location only steps to river. Enjoy walks along the Delaware River, spot wildlife, watch the sailboats. Community features pool, tennis courts and clubhouse. Tenant occupied - lease is a month month. please allow 24 hour notice to show.


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Can virtual reality reduce pain and anxiety in children?
Andrew Mernin
Virtual reality can decrease pain and anxiety in children undergoing intravenous (IV) catheter placement, a new study shows.
Researchers tested whether virtual reality (VR) could prevent pain and distress for patients undergoing peripheral intravenous catheter (PIVC) placement.
It was based around a VR game which is simple but requires focus and participation.
Patients in one group used VR throughout the procedure, while those in another group received standard of care, which includes simple distraction techniques and the use of a numbing cream. The patients who used VR reported significantly lower levels of pain and anxiety.
The study was led byJeffrey I. Gold, PhD, an investigator at The Saban Research Institute of Children's Hospital Los Angeles, who has been investigating the use of virtual reality (VR) as a technique to help children undergoing painful medical procedures for two decades.
His research shows that the technology can have powerful effects. VR works so well that Children's Hospital Los Angeles now offers it routinely for blood draws.
"Some patients don't even realise that their blood is being drawn," says Dr. Gold. "Compare that to a child who is panicking and screaming, and it's a no-brainer. We want kids to feel safe."
Dr. Gold's team reports the results of a study to test whether VR could prevent pain and distress for patients undergoing peripheral intravenous catheter (PIVC) placement.
"We can actually reduce pain without the use of a medication," says Dr. Gold. "The mind is incredibly powerful at shifting focus and actually preventing pain from being registered. If we can tap into that, we can make the experience much better for our kids."
This is one of the first studies to analyse the effects of VR not only from the patient perspective, but also from that of the clinician and the patient's family or caregivers.
All three of these groups reported a more positive experience with the use of VR. Dr. Gold calls this triangulation of data – gathering information from three perspectives in order to improve patient experience.
"We started this as a way to mitigate pain and overall distress in children. But caregivers and healthcare providers are also reporting improved outcomes, effectively treating the patient clearly has a ripple effect."
A patient experiencing anxiety about their procedure may tense up, making it more difficult for the clinician to find a vein and insert the catheter.
If multiple attempts are necessary, a child's fear may amplify, causing a snowball effect, which in turn may impact medical adherence and ultimately long-term health outcomes.
If, on the other hand, the patient plays a virtual game while undergoing the procedure, she may relax and experience less pain, improving the overall experience for the child, the family, and the healthcare provider.
"Stress actually causes veins to constrict," says Dr. Gold, "but you don't need to know the physiology to know that it's better to have a relaxed kid."
The ripple effect goes further. A child's experience during a visit sets the tone for future visits. If the experience feels traumatic, the child and family may be less likely to adhere with scheduled visits or may feel more stressed coming back to the hospital.
"We don't want a child's healthcare experience to be another adverse childhood experience," says Gold. Adverse childhood experiences, also called ACEs, can lead to poor health outcomes.
"We care about the healthcare experience that children have," says Dr. Gold. "By reducing fear associated with routine procedures, we prepare the child to begin treatment with a more positive outlook, and this can affect their health for a lifetime."
Northumbria Healthcare picks CliniSys to modernise laboratory processes
Theatre kitting solution could help hospitals reduce backlog
Pingback: Medisafe comment: Could the future of digital health transform RX?
Pingback: Basel Area – the health tech hotspot


Coming at us from Nova Scotia, the quartet of Hitman have resurfaced with their third EP, following a single back in April of this year. Wasting no time, the EP launches off with "Curtain Call", a two-minute burner of hard stoner rock, which lays down hard riffs while clearly establishing the style used by the rest of the songs. "Under the Weight" pumps up to five minutes and change, shifting to a slightly slower groove that still bristles with spiky guitar while flexing its bass muscle. Thanks to the extra run-time, the drums and guitar get some more room to shine, with a few breaks and a solo or two indulging in some gritty swagger.
They keep a good swing going through a honky-tonkish bit of cowbell counter-point, then flip right on into "Nero", the EP's advance single. Here, the edge is rougher, the grooves harder, and the soloing wilder, all of it making clear why this track was picked to stand on its own and pique interest. Lastly, the double-header of "Enchanted Wizard / Hail the Outro" brings things to a finish on the back of big bass slams and some of the EP's sharpest guitar solo work, brandishing a fistful of flair while cranking out the attitude. A well-rounded set of tracks, with plenty of hooky little moments to lodge in the ears and memory, this batch of tunes should have fans well satisfied while drawing in a good crowd of new listeners to hear what they'll come up with next.


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Text Sets for Teachers: Finding the Line: What is "Good? Text Sets for Teachers: Gender's Lens: Society's Views and Expressions of Gender
Text Sets for Teachers: Good vs. Evil: Exploring Morality Through the Holocaust
By Kellee On December 23, 2015 · Leave a Comment · In Historical Fiction, Language/Style, Literature Circle/Book Clubs, Multicultural, Teaching, Theme
Good vs. Evil: Exploring Morality Through the Holocaust
Text Set for Night by Elie Wiesel
created by Kellie-Anne Crane
It is of the utmost importance that teachers prepare their students for their futures, whether that includes continuing their education or entering the work force. No matter what path students choose to take, there are certain concepts that all people need to recognize and consider as human beings, like the concept of morality. Everyone is confronted with moral decisions on a daily basis—whether it is a monumental decision, or even something as small as deciding to give the last cookie to your sister or to keep it for yourself. The events of the Holocaust and World War II are incredibly essential to study, not only because these events are our shared history but because of the unbelievable turmoil faced by millions. Teachers must help students to understand the gravity of this time period and work to teach it to students in a way that is both approachable and comprehensive.
By exploring the concept of morality through the Holocaust, students will be educated on what is perhaps the greatest tragedy of mankind and be forced to contemplate the morality of multiple scenarios throughout the holocaust. As upstanding citizens, we would like to think that we do not need to worry about anything like the Holocaust—but the fact remains that it happened less than a century ago. Teachers must help students examine the decisions and events that occurred during this vile period on a personal and real level so that they can gain a deeper understanding of the moral struggle faced during the era. Our youth must be educated on our past, both good and bad, to ensure that a similar situation such as this never arises.
Anchor Texts (although other texts may be used!):
Night by Elie Wiesel
Novel Excerpts
The Diary of a Young Girl by Anne Frank
The Book Thief by Marcus Zusak
Number the Stars by Lois Lowry
Maus I: A Survivor's Tale by Art Spiegelman
Terrible Things by Eve Bunting
The Butterfly by Patricia Polacco
The Sneetches by Dr. Seuss
"Empty Chairs at Empty Tables" from Les Misérables
"Hide and Seek" by Imogen Heap
Winston Churchill's First Speech as Prime Minister on May 13, 1940
President Roosevelt's Speech to Congress on December 8, 1941
Adolf Hitler's Speech Declaring War Against the United States on December 11, 1941
Pope John Paul II's Speech at Israel's Holocaust Museum March 23, 2000
"The Creed of a Holocaust Survivor" by Alexander Kimel
"The Action in the Ghetto of Rohatyn, March 1942" by Alexander Kimel
Lawrence Kohlberg's Stages of Moral Development
Timeline from 1918-2000
Viktor Frankl: Why Believe in Others TED Talk
"Oprah and Elie Weisel at Auschwitz" (1:20- 6:05)
"Man that saved hundreds of children from the Holocaust surprised by them decades later"
"Ghettos Under Nazis" by Susan D. Glazer
"Baking Saved this Man during the Holocaust, and Is Still His Livelihood" by John M. Glionna
"3 Famous Moral Dilemmas That Will Really Make You Think" by Lenna Son
"German Woman, 91, is Charged with 260,000 Counts of Accessory to murder as Prosecutors Accuse Her of Being a Nazi SS Radio Operator Who Served in Auschwitz"
Guiding Questions
Are there tenets of morality that are universal?
Can a person's sense of morality be altered by their situation or surroundings?
Did the conditions of the holocaust change people's morals? How so?
Are there good and bad people?
What can we learn from the tragedy of the Holocaust?
Consider one of the famous moral dilemmas we have discussed. What do you believe is the right answer in this context? Why
What makes someone a good person? A bad person? Are there clear binaries between the two?
Choose a text (novel, story, video, song, etc.) from class that has helped to give you a better understanding of the holocaust. What did you learn from this text? Why is it important?
Choose a quote or passage from Night. What does this scene say about morality?
Is there any moral(s) that you find to be universal, as in followed and accepted by everyone? What is it and why is it so widely accepted? If not, explain why you think there is no universal set of morals.
A special thanks to Kellie-Anne for this inspiring text set! We think this text set would be useful for many anchor texts! What do you think?
and `1111`
Tagged with: Morality • Teaching • Text Set • War • Writing


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Q: Can IntelliJ show origin class for methods in code completion popup? When I use code-completion in IntelliJ it will show the method signature including the name, the parameter(s) and the return type.

Eclipse one-ups this and shows the class where the method "comes from" (which is better in my opinion)

My question is: Is this possible in IntelliJ?
I have found this question on SO which goes somewhat in the right direction but at best I would love to have the class names as described above, not the filtering. Otherwise this is really hard to google.
Screenshots are from random google searches, simply for ullustration, but it looks the same for me

redpajama_set_name: RedPajamaStackExchange


Buy Bialetti® Easy Nonstick 10-Inch Aluminum Saute Pan in Brown from $19.99 at Bed Bath & Beyond. The Bialetti Easy Saute Pan features heavy-duty aluminum construction for even heat distribution plus a signature ceramic nonstick interior for easy food release. Comes with an ergonomic, heat-resistant Bakelite handle for a secure, confident grip.The Bialetti Easy Saute Pan features heavy-duty aluminum construction for even heat distribution plus a signature ceramic nonstick interior for easy food release. Comes with an ergonomic, heat-resistant Bakelite handle for a secure, confident grip.
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The Scanpan Brund Quick Heat 10" Saute Pan features a special energy absorbing base that makes heat up times much faster and is suitable for all cooking surfaces, including induction. PFOA-free nonstick interior ensures easy food release.


I spent a few minutes with the new Dues Ex and am excited to get a chance to play it in my own living room. While the graphics are nothing extraordinary, it looks like Dues Ex: Human Evolution will excel in story telling. One thing that is difficult when demoing these types of games is that you have to remember that this is a story driven game and it's difficult to jump in for a demo. What's cool about Human Evolution is that you can decide how you want to approach missions and the gameplay/dialogue will be different depending how you approach said missions. The RPG element to the game looks fascinating as you improve your character through new human improvements. While I should be disappointed with what little I got to play with the demo, the video Square Enix had playing still showcases how this title should be fun for any RPG and sci-fi fans.


text:
Need to practice some French with native speakers and don't have a passport? Take a (long) drive up to Madawaska, Maine, which holds the distinction of being the Frenchiest town in America, a place where, according to the 2000 US Census, 83 percent of its residents spoke French as their first language (!). These are the descendents of the Acadians, who came from the west coast of France in the 1600s, were chased out of Nova Scotia by the British before the revolution, and scattered among the coastal US colonies (some ended up in Louisiana, where they became Cajuns), and finally returned after the war to the St John River valley.
I was recently up there, and the French they speak, I was told, is closer to the French of 400 years ago than Parisian French is today. It certainly is weird. I wasn't sure it was even French till I heard a "mais, oui!" But because of their proximity to Canada they also can speak "formal" French, so I had the unique experience of ordering dinner in French in a Chinese restaurant in Maine! (And the food wasn't bad.)
claire courbet October 19, 2013 at 8:38 AM
hi, i'm claire, french, 20 years, lives next to paris, i ill be happy to learn french at english people who could help me in english !
write me : claire59610@hotmail.fr


The Osprey Poco Carrying Case provides a safe, secure and protected space to store the Poco Child Carrier. With a compact design enables the case to pack into its own pocket when not in use, it can also easily be stored in the lower compartment of the child carrier. Adjustable shoulder straps ensure carrying comfort, and ID card holder makes it easily identifiable on airport baggage carousels.


text:
Абхазские пираты — известный феномен в средневековье, активно орудовавшие на территории Чёрного моря пираты из Абхазии.

История

Заря абхазского пиратства началась с объявлением о суверенитете Абхазского княжества. основном набеги абхазских пиратов были направлены к берегам Гурии, Мегрелии и Турци, но также проводились грабежи торговых кораблей даже в районах Крыма и Босфора.
Особенно пираты прославились в своих крупных набегах на соседей мегрел и гурийцев зафиксированных в  1571, 1572, 1672 гг. Часто разбойники действовали в союзе с адыгами, и мегрелами против турков в 1701-1714 гг. После кавказской войны пиратство практически исчезло.

Виды кораблей

Значительная часть пиратов из Абхазии использовала не крупные безпарусные лодки мелкой вместимости экипажа, они обладали мобильностью и их можно было вручную с лёгкостью переносить по суше, Эти лодки назывались "ашхуа". Ашхуа использовали также жители таких сёл как Соук-су чтобы спускаться на речки которые впадают в Чёрное Море. На этих судах также ловили дельфинов, из-за веса дельфинов лодки могли тонуть, но как сообщает Ф.Торнау абхазы были хорошими плавцами и даже умели плавать "саженками". Существовали также крупные корабли именуемые "агба" вместимостью 200-300 человек Во время набегов на таких кораблях часто захватывали пленных которых продовали в рабство. Французский путешественник в 1826 г. зафиксировал наличие так называемый им "Абхазской лодки" с восьмью вёслами и даже зарисовал её.

Бухты абхазских кораблей

Список зафиксированных  существоваваших точек  запуска кораблей и бухт которыми возможно могли пользоваться пираты

Гагрский р-н:

 Анышьхцарта

Сухумский р-н:

 Сухумская бухта

Гудаутский р-н:

 Ашхуатхэахырта
 Соук-су
 Аилага-абыку

Очамчырский р-н:

 Ашхуацэырта
 Ашхуаахэарта
 Ашхуатаныкуарта

Сообщения путешественников о деятельности пиратов

Французский путешественник Шарден, который находился в Мегрелии в 1672 г. и был свидетелем набега абхазских князей, пишет: "12-го (ноября - Ш. И) предполагалось пересесть в лодку, но этому помешало известие (вполне потом оправдавшееся), что лодки черкесов и абхазцев крейсируют вдоль берегов Мингрелии. Они угнали местные лодки, а с ними и ту, которую я нанял".

Сулхан Саба Орбелиани сообщает:

"Гурию я судно не могу вести, абхазы возмущены, боюсь, и, если хотите, отправляйтесь на маленьком судне... "

Вахушти Багратиони утверждает что пираты на абхазские пираты море были действенно "могущественны":

"по морям ходят на судах..., в которые они садятся по сто, по двести и по триста человек, и нападают в пути на суда османлисов и лазов-чанов и чаще всего у побережья Мегрелии и Гурии".

Путешствнник Дюбуа Де Монпере сообщает о пиратах из Сухума напавших на турецкий торговый корабль в 16 июня, 1833 г.

"Остановили его и бросились разбирать находившийся на нем груз, ранив при этом несколько человек."

Заметив русский корабль на котором путешствовал Дюбуа пираты скрылись.

Примечания


WellSpan Health, an integrated delivery system based in York, Pa., has surpassed the national average compliance rate for Severe Sepsis and Septic Shock Early Management bundle (the national average according to data on Hospital Compare is 50%), recently boasting an 85% compliance rate for the bundle. WellSpan executives credit a year-old quality improvement initiative that involves leveraging the electronic health record and a remote patient monitoring team to identify and treat patients with sepsis early. The initiative launched in May 2017 after WellSpan began its transition to an Epic EHR system.


StartupJuncture started in november 2012 as a blog bringing almost daily news from the Dutch startup scene. Now, after five years and 4 months, StartupJuncture will scale back to one post each quarter. We are a bit sad that we have to scale back, but mostly we are happy about the way the Dutch startup scene has developed in the past five years.
Some of us thought a lot was happening and we should cover it and give the Dutch startup ecosystem an international platform.
Some of us thought that not enough was happening and that a blog might inspire people to do something.
Some us thought StartupJuncture could become a successful media business.
Some of us thought it would be a nice for-free side project while building other businesses or investing in startups.
Either way, we all recognized that it made sense, in a country as small as The Netherlands, to work together. We joined forces and created StartupJuncture as a platform where people could blog about the Dutch startup scene.
StartupJuncture started with four readers (the four founders) but has grown significantly since then: Since we switched to google analytics in 2014 we have had 1.1 million pageviews. 7800 people have decided to follow us on twitter and 3000 on Facebook. Even more importantly our example has inspired others to also cover Dutch startup news in English. This has helped to put The Netherlands on the international startup map, attract international talent and allowed more startups to grow into real business. Our role in the overall growth was small (many people in The Netherlands have contributed to the startup successes, most importantly the startup founders) but we are satisfied with the growth of a real ecosystem.
As of this month, we will only make 1-2 posts per quarter. We will make a quarterly funding overview at the end of each quarter, like our previous overviews (see for instance startup funding Netherlands 2017, startup funding Netherlands 2016, startup funding Netherlands 2015 and startup funding Netherlands 2014). Occasionally we will publish guestposts if the quality is good, the topic is relevant and we have some time to publish. Otherwise we will be inactive: we will not cover news, we will not read press releases and we will not respond to questions.
If you are interested in following the Dutch startup scene, we recommend you to use the following alternatives: Silicon Canals, Sprout, Emerce, StartupAmsterdam, tech.eu and occasionally Techcrunch. To get in touch with the startup scene, contact accelerators like Yes!Delft or Utrecht!Inc or visit accelerators like Rockstart and Startupbootcamp.
First of all we would like to thank our readers. We also would like to thank the many founders we interviewed over the years. By sharing their stories they increased our understanding of the ecosystem and we hope they will continue to do. Last but, defintely not least, we thank all our contributors. This includes our regular editors (Lorenz van Gool, Suzanne Blotenburg, Sabine de Witte) but also other team members such as Joren Frielink and Thomas van der Bijl from Knijbel, Moniek Veltman, Joffrey Mandersloot, Adine Rooyakkers and all guest bloggers. Also thanks to our other supporters and contributors, including KPMG, Node1 and also Ruben Nieuwenhuis and the other past and current StartupDelta staff.


text:
/*
 * Do not modify this file. This file is generated from the codedeploy-2014-10-06.normal.json service model.
 */
using System;
using System.Collections.Generic;
using System.Xml.Serialization;
using System.Text;
using System.IO;

using Amazon.Runtime;
using Amazon.Runtime.Internal;

namespace Amazon.CodeDeploy.Model
{
    /// <summary>
    /// Represents the output of a get deployment operation.
    /// </summary>
    public partial class GetDeploymentResponse : AmazonWebServiceResponse
    {
        private DeploymentInfo _deploymentInfo;

        /// <summary>
        /// Gets and sets the property DeploymentInfo.
        /// <para>
        /// Information about the deployment.
        /// </para>
        /// </summary>
        public DeploymentInfo DeploymentInfo
        {
            get { return this._deploymentInfo; }
            set { this._deploymentInfo = value; }
        }

        // Check to see if DeploymentInfo property is set
        internal bool IsSetDeploymentInfo()
        {
            return this._deploymentInfo != null;
        }

    }
}

redpajama_set_name: RedPajamaGithub


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Facilities Benchmarking & Analysis
Facilities Assessment & Planning
Campus Sustainability
Company | News | Sightlines Rolls Out Free "Sightlines Insights" E-Newsletter
Sightlines Rolls Out Free "Sightlines Insights" E-Newsletter
Monthly email newsletter part of company's program to serve as resource to university business officers on important facilities management and investment issues
Sightlines, a leader in helping academic institutions better manage their facilities and capital investment strategies, has launched a free monthly electronic newsletter that provides university business officers with deep insights into facilities asset management issues.
"Our goal is to serve as a trusted resource for campus leaders to help them gain a deeper understanding of how to bridge the operational requirements of financial management and facilities management," said Jay Pearlman, associate vice president at Sightlines. "Drawing on our comprehensive database and unique perspective gained from our work at more than 450 institution, we feature a wide range of free content in 'Sightlines Insights' that help academic institutions make better decisions about their facilities."
This month, for example, "Sightlines Insights" includes a helpful article by Sightlines Vice President Jim Kadamus that offers ideas for how to best engage boards of trustees in productive conversations around facilities investments.
"Our free monthly e-newsletter is part of a larger program we rolled out this year that is designed to share our unique content with the education community so that we can all learn from each other's experiences and work together to improve the learning environments for America's students," said Pearlman. "Since launching this program in January, we've seen traffic to our website double, so clearly we are tapping into a real need in the marketplace for objective, actionable information related to academic facilities management."
The Sightlines Higher Ed content program includes weekly blog posts on key facility policy and management issues, the monthly "Sightlines Insights" newsletter delivered via email, substantive content produced monthly – such as research reports and Q&A profiles with industry leaders – and an annual report on "State of Facilities in Higher Education" produced by Sightlines. The 2014 annual report is in development now and will be published in early-June.
Sightlines also provides visitors to its website (www.sightlines.com) with access to a knowledge library that includes recorded webinars, presentations and various research pieces that deliver unparalleled insight into current trends and best practices in the higher education facilities management industry.
Sightlines, A Gordian Company © 2020 Privacy Policy 405 Church Street, Suite #2 Guilford, CT 06437 Phone:(203) 682.4950


text:
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Contracts are par for the course for many small business owners. However, failing to draft them correctly could result in you losing money or, in extreme cases, having to shut down your business. To avoid these situations, it's best to hire a business law lawyer to help you prepare or negotiate your contracts so that you can be sure that you are protected. If you ever find yourself in court because of a contract you were involved with, a business law lawyer helps you navigate the legal system so that you have the best chance of winning your case.
Purchasing or leasing real-estate can be a daunting task for a business owner. If you don't know what you're doing, you could end up with the short end of the stick, especially when it comes to problems with the building that could lead to public health code violations. A business attorney will have the know-how to order a full inspection or environmental study as well as negotiate a contract that will benefit both parties.
Start-ups face unique challenges that established businesses do not. When you're starting out, it's vital that you seek advice early on the best type of business entity for your company. You don't want to make mistakes setting up your business, as this can cause more serious issues for you down the road. Your business attorney will make sure that you choose the right solution and that you correctly file the necessary paperwork to get your business started the right way.
It's important for business owners to do everything they can to protect what they've built. A qualified business attorney will help you make the right decisions, guard your precious assets, and maintain your peace of mind.


You are here: Things to Do > Lawnmowers Independent Theatre Co.
The Lawnmowers Independent Theatre Company is a unique company run by and for people with learning disabilities. We are based in Gateshead in the North-East of England. The original group formed in 1986 and after years of hard work they chose to set up an independent company. In January 2001 the Lawnmowers Independent Theatre Company, a charitable company limited by guarantee, was established. Over the last twenty years we have led hundreds of workshops and have researched, devised and toured work, mainly to learning disabled audiences. We have produced videos, booklets, DVD's, run residencies, summer schools, hosted nightclubs and established an apprenticeship scheme.
The Members of the Company place themselves alongside the daily struggles faced by people with learning disabilities. All of our projects are working towards a future, just and equal society. The company wishes to play its part in honouring and developing the culture of people with learning disabilities and intends to research, explore and develop new ways of working. The company values and intends to support, places where people with learning disabilities can explore and develop their ideas and help plan and take control of their futures.
Today The Lawnmowers Independent Theatre Company has over 35 members, eight of whom are paid staff, two of whom have learning disabilities and a committed board of trustees. Our company's work is very much in demand and we continue to explore ways of using theatre to champion the rights of people with learning difficulties, plant the seeds of social change and build a broader and better culture in the communities that we live.


text:
Populate the side area with widgets, images, and more. Easily add social icons linking to your social media pages and make sure that they are always just one click away.
Pure Driving School
Benecke, Elkemann, Grabovsky, Heinrich, Wallmeier, Wenig, Wolf
Champaign and breakdown service in the Ardennes
There was no rest having just completed the 12 hours of Bathurst, The team switched their focus to the penultimate round of the NEO Endurance Series at Spa Francorchamps. The Belgian Grand Prix Circuit is always a lot of fun for the drivers and offers long straights and many opportunities for overtaking. With only one roud remaining at the famous Le Mans circuit, all the teams were battling hard to position themselves for the best possible starting position at the last race with double points on offer.
The qualifying took place at the same time as the opening hours of the Bathurst race, which made it quite tricky for the drivers to split up for both tasks. Netherless, our Prototype team managed to take yet another pole position driven by Maximilian Benecke with a time of 2:04,003. Our GTE teams also managed to have great qualifying runs with the #71 PRT Blue car starting from 2nd and the #72 PRT Red car from 4th. The strong qualifiying results made the team very positive about securing top results in the upcoming race.
A great start and opening laps by Max in the prototype meant he could really show his dominate pace and lap by lap increase the lead to the chasing Evolution Racing Team car. In the GTE class, our #71 PRT Blue car with Max Wenig starting from second used the draft of the pole setter Mitchell DeJong to immediately make the pass on the #81 VRS Coanda car right after the Kemmel Straight into Les Combes. Patrick Heinrich driving the #72 PRT Red car also had a great start and safely held onto his 4th position right behind Ricardo Castro Ledo in the #79 Core Simracing car.
Everything was looking really good for the team having broken away from the rest of the field. Unfortunately the situation didnt last long. As the Prototype traffic started to come through problems began to strike. A HPD dived down the inside of the Core Simracing car into Blanchimont and made the driver go wide and lose his car due to lack of grip off the racing line. Unfortunately the car spun to the inside of the track right into the #72 Red car with no chance of avoiding the incident for Patrick Heinrich. Both car's made contact and ended up in the wall, with both cars retiring from the race.
If that wasnt enough bad luck for one race more was to come!, the #71 GTE Blue car after having slightly pulled away from the VRS Coanda car in 2nd started to hit some troubles as the tire temperatures started increasing rapidly and ultimately made the gap melt down to nothing. While the two vehicles were going side by side into the Les Combes corner complex contact was made resulting in a spin for Maximilian Wenig in his #71 Blue car with a loss of time of about 10 seconds. Luckily, the cars were fine, and both could carry on without any issues. Max Wenig found himself back in third position behind the Thrustmaster Mivano GTE car.
The #7 Prototype car of Max Benecke & Patrick Wolf did a great job throughout and extended its lead even more as the race went on. Both did their laps without any major issues and dealt with traffic perfectly. The #71 PRT GTE Blue car decreased the gap to the Mivano car in front and finally, with Jonas Wallmeier behind the wheel managed to overtake the Italian team. However, the distance to the leading Ferrari with Joni Takanen as its second driver was too big and there was no way to close down the gap pace-wise with the time remaining.
In the end, there was also some minor trouble with the Prototype car. Patrick Wolf behind the wheel came up on a slower GTE who just lost it at the exit of turn 14, Campus, and spun to the inside of the track hitting the side of the HPD and pushed it into the wall. With substantial damage, the team decided to pit for repairs immediately and lost about 40 seconds in total. This made the fight back to the lead seem impossible at the tim. Netherless the two drivers of Patrick Wolf and Max Benecke gave it everything they had and managed to close up the gap to the leader.
Surprisingly for both drivers, they managed to successfully get back into the lead with just five laps remaining of the race. They brought home their 5th win in 5 races, just 2.3 seconds in front of the Thrustmaster Mivano Prototype car and 2.4 seconds of the Core Simracing car, which apparently is an incredibly close finish.
The #71 Blue GTE car, however, was not able to close down the gap to the Coanda Car and came home in well-known second position with MSP Phoenix being the first Ford of the season to step on the podium in third place.
Overall, the fifth round of the NEO Endurance was a success for the team, even though our #72 GTE Red car collects another DNF, We still managed to bring the Prototype car home again in first place with maximum points which gives them a comfortable lead in the championship going into the final round at 24 hours of Le Mans and takes some pressure of the drivers. With their second position, the GTE Blue team has now made the big pass in the championship securing P2 of the overall standings. Theoretically, there is still a chance of winning the GT championship, but with the VRS Coanda #81 car having a 51 points lead, chances are slim and we will need a lot to happen on the French street circuit.
With the 24h race being at the same time as the Sebring race in the Blancpain GT Series, the team again has to deal with task conflicts during the opening stints of the race, but we are positive that our drivers are capable of such a challenge and looking forward to the final round of the NES.
Thanks a lot to Jamie Wilson for the HPD pictures!
Watch the broadcast here:
ABOUT Pure Racing Team
The Pure Racing Team is a professional SimRacing Team on iRacing.com with more than 15 active drivers.


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Nomad Life
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The Humble Beginnings of Project Nightfall's Agon Hare
Posted by Paul @ Travel is Life | Sep 18, 2018 | Travel Bloggers, Videos | 0 | This post may contain affiliate links
Hey traveler, while you're here join my friends list to get all the perks I offer at Travel is Life.
Agon Hare's top video on Facebook exceeds 25 million views and his other videos regularly reach millions of views and receive tens of thousands of shares – so the guy is doing something right when it comes to creating powerfully engaging video content.
He runs a channel called Project Nightfall with over 462 thousand subscribers, and you might also recognize his name from his work with the Nas Daily team. Agon travels full time with Nas Daily and Dear Alyne recording, editing, and producing Nas's one minute daily videos.
See Also: 21 Things I Learned From Nas Daily About Travel Vlogging
Last week I interviewed Agon about how to create attention grabbing videos for Facebook. The interview was amazing – the guy is a genius – and I learned strategies that I'll be implementing into my own videos on Travel is Life. However, before Agon revealed his secrets to making viral videos, I wanted to learn more about the man behind the performer, how he got started with video production, and the path that led him to traveling the world and producing videos for Nas Daily. It's quite an amazing success story!
You can watch the 15 minute interview at the top of the page, on YouTube, or on Facebook. There's also a transcribed version below.
🎙 The Full 1 Hour Interview
In the full interview, Agon shares his video production secrets so that you too can learn to create captivating and viral videos on your channel. He also shares some insight into his processes for script writing, planning, filming, and editing, which have allowed him to amass millions of views on his videos.
💬 15 Minute Interview Transcript
Agon, most of us listening know the performer Project Nightfall from your videos, but I want to ask you, who is the real Agon Hare? Before we get started, what should our listeners know about your background, personally, professionally, or both?
Who is the real Agon? Okay.. I'm a guy from a small Polish city. I come from a musical background. I started my journey with like chasing my dreams and working really hard as a singer and music producer back in Poland, and at some point I said to myself that I want to take it seriously. So I decided to leave to London.
That was exactly seven years ago. And in that time, I was busking on the streets, I've worked in recycling center, I was working in food industry and fast food chain, and after five years of really hard work, it started paying off, and now I travel around the world. And from that experience of coming from a humble background and a lot of work that went unnoticed, now I feel like I can have some message behind my words because I've been like most of the people – from zero to somewhere.
When did video enter the mix? You said seven years ago you went to London, but when did the videos start?
Video entered the mix two years ago, two and a half years ago exactly, and it's a funny story because I was making a music video of a professional video maker, and when we finished, it took him half of a year to bring me that music video. And I was so frustrated. I was telling myself I can't wait. My hype for this song died and I wanted the song to go out, but he couldn't edit the video on time, so I said to myself, "Okay I'm going to learn music video production, and the next video I release will be my own."
And that's how it started. The first few videos were horrible, and I quickly caught up. And once I caught up I got into mix of working with people who are successful on YouTube and that's how my professional video making started.
I'm very surprised to hear two years ago. That's insane to me, and I think probably insane to a lot of people listening who have heard your videos and seen your videos, because with the way you edit your videos, I would've guessed at least 10-15 years experience. Possibly you're a prodigy who got started when you were six years old for all I knew.
You know it's possible that in two years I've managed to push six years of work cause once I started video making, I saw an extreme difference in my music making skills and video making. I felt really really weak with my video making so I was catching up working like 10 hours every single day, putting random videos that I never released on the timeline in Premiere Pro back then and just editing them to learn, and watching tutorials, and just pushing it all the time. And I think it's the fact that I had the experience of making music for so many years so I could sit on my computer for 10 hours mastering one note in a song that made me learn video production in a really intense way.
That's fantastic. And during this past two years, about one year ago, that's when you joined Nas Daily's team. And from what I know, you edit his videos, you travel with him full time, and you help him film and do everything involving producing. How did you first get connected with Nas and start working together?
Okay, so about 200 days ago, Nas had this thing in Morocco. Now we do it together, but before he was doing it by himself. He organizes boot camps for creators. And back then, a friend tagged me on his video, on his post, because I wasn't watching his videos like every day, so probably I wouldn't notice it, but my friend Hartic, if you're listening to it, thank you for tagging me, you changed my life! (laughs) He tagged me in a post and said, "Yo, check this out!"
Nas created a video saying, "Join me to travel with me for seven days. We're going to learn from each other and all this stuff." So I wrote him an email and after that email, they wrote me back, because it's also his girlfriend Alyne who reads these emails, and they said, "Yo come over to Morocco." They really liked my video. I did a video on YouTube and they saw big potential in it.
So they invited me to Morocco – I came there. I packed my bag for nine days exactly because I had my tickets bought to Los Angeles. I was already established as an editor on YouTube and I didn't plan on staying at all. But after about five days of being together, we released this big video called We Killed the Internet on Nas's channel that went viral and was really strong and realized that we worked really well together.
So Nas calls me in the room and he's like, "So how about you join us on travel. We go to Japan next." (laughs) And back then I was like, "Oh my goodness. Okay." I didn't expect that.
I wasn't packed. I was ready to fly to Los Angeles and just do my life and stuff. It took me five minutes to decide, and I was like, "Okay". I quit my YouTube job and I started traveling with him. I have no idea how long it was going to last, if we were going to be together forever or not, cause we might hate each other at some point. I had no idea how much money there will be in it. But I can tell you for sure that it will be a lot of fun and a lot of hard work. And it was. After 5 days of working with him, it became obvious to me that I had to do it.
I remember the video. I remember his call to action for people about this boot camp. A few people tagged me in it. I've been watching Nas's videos for a while, and back then… I've actually introduced a lot of people to his videos, I think the world of him… and folks tagged me in it, but I was so brand new to making videos myself then, I didn't even.. I had zero idea what I was doing. I said I'm not ready for something like this. But I remember, if I'm not mistaken, it was you and a couple other folks that went to the boot camp?
Yes it was four other people.
When you submitted a video to him, was it a video you created specifically for him, to get his attention, or was it another video you had produced?
It's totally insane coincidence. About a month before I made my first scripted video ever without even seeing Nas's videos. Up until then I was making vlog content, so I would just run around with camera and be entertaining, and have fun and stuff like this, but I decided to make one scripted video. And once I finished that video and I saw Nas's video afterwards, I realized that his videos were kind of similar to what I did.
And I feel that's what caught his attention because he saw a part of him in my video, and I didn't even see him making his videos. So I kind of had his style shaped in a different form, so I could put a new twist into his videos. And after like 600 videos he made, he needed that extra fresh energy. So it wasn't specifically for him, but it was in a style that was attractive for Nas Daily.
I didn't realize the story, that you had a job lined up, that you were on the way to Los Angeles. What was it about Nas, his energy, his personality, that made you so confident? Or were you confident to take that big gamble – and I have to call it a gamble?
It was a gamble! It definitely was. But it was so obvious to me because before being on Facebook and joining Nas, I was working on YouTube and I was working with many YouTubers who vlog, who make videos and who are popular in American market, and I was mainly their editor. But I also went to Los Angeles and lived on Vine Street which was, which still is, a place kind of like a social media entertainment middle of the world. All of the big people we see on the Internet live there. And I was in that environment and I felt that it's not necessarily where I belong, because I never wanted to just create entertaining content.
You know, I always felt like it would be great if I could have some positive impact on people with my videos, and once I joined Nas, I realized that you don't have to be a clickbaiter and a sensationalist guy who always looks for ways to attract people with nude girls or stupid titles, you just have to be confident in what you say. You have to be inspirational or just intelligent with your content. And it was such a breath of fresh air to me to a guy who works on YouTube, so I created my Facebook account like a month after being with Nas. I never even thought of making videos on Facebook, but the power of this platform is just awesome.
And Nas himself was real. I had a pleasure of working with a lot of YouTubers, including PewDiePie, for example, who's the biggest guy on YouTube, and I felt with PewDiePie he was real too. I found a genuine human energy when I worked with PewDiePie. And I felt the same thing with Nas. When I met him, it was the same guy as I see in his videos. Very smart, very believing in what he does, and wanting to make his videos for the people and not just for himself. And that made me realize that I don't want to go back to Los Angeles. I don't want to have a high paid editors job with entertaining YouTubers, I want to risk it all and make my own channel.
I felt the same thing from Nas – a really really unique creator who has a great message and is just real. Someone who believes in what they do and doesn't use their audience as a tool to make money, and to use for his own gain. And that was something that I felt I wanted for myself too. So it really attracted me and it was obvious for me to join his team.
I lived in Los Angeles for three years, right in Los Feliz, close to Hollywood, and I know that it's not the place for everybody. And from the outside looking in, I know this is the first day I'm talking to you, but I've seen your videos, and I think that you've found your place. Because you especially, but the three of you, always look like you're having so much fun in your videos. I don't know if people who see the videos, and see how much fun you're having, realize just how hard you work and how many long days you put into creating these videos. So I wanted to ask you, what is a day in the life like on the Nas Daily team and the Project Nightfall channel?
Our days are insane, and this is the perfect timing because yesterday I had one of the craziest days. Basically what happened yesterday is Nas doesn't have a visa to Malaysia, he can't go there, so we had to flew me into Malaysia just for 5 hours to make a video with a guy who's been trapped in the airport for six months. He lives at the airport because he's a Syrian refugee whose passport expired and Malaysia doesn't have a refugee status, so he has to live there until someone helps out. And I hope that the video we made will push it.
So the day is like a constant grind. We work almost all the time. When people ask us on the meet ups, "How long does it take to make one video?" – we used to say, "Okay 10 hours." Then we said, "12 hours". But when we spoke back home we realized that from now on we're always going to say, "24 hours of video making every single day," because even when the video is finished, we constantly think of what we have to do. Nas scripts all the time in his head. We have extra videos on the side. The one minute videos sound so easy to make, but sometimes we have to travel for 3 hours to get 2 shots. We never use stock footage. We always try to deliver the best thing and finding ideas takes forever. So it's a lot of hard work, but it's so rewarding, that as you said, it looks really fun.
And when it comes to Project Nightfall, I have one day off per week, so this is also a really intense time for me because every time I have a day off, I need to make sure that before that, I have my script for a video done. So on my day off, I will wake up early around 8 in the morning. I will quickly prepare myself, go outside, and record all the lines from the script, and everything creative that I thought before, I will record this. I'll come back home and then I'll edit for about 10-12 hours. So my days off are actually also the most intense days. There's never a day off in the daily content video making.
When you're traveling, what type of work do you typically do? When you're in the airport waiting, when you're on the airplane, when you're in the taxi cab, when you're on the train… what happens during those times?
When we travel we usually – we know in advance, okay. We know five days before – okay we're going to have a flight, so we usually have a video lined up. We try our best to make two videos before that so we can have a video lined up, but sometimes it doesn't happen. Sometimes we don't have a video so we need to come out with a video that aligns with traveling. Like for example, we had a video, The Best Layover, which we had a layover in Philippines for 5 hours and we got stuck at the airport, but we still managed to have gather a big meetup of people, record a video with them, then edit it on the plane – hope that the battery lasts long enough. When the flight is long, it's all about editing on the flight.
So there are times, if I'm hearing correctly, that you need a video for the very next day?
Yes, all the time! Almost every day we make videos on the day before.
That makes me feel a lot better. I put out a video every Tuesday. That makes me feel a lot better working into the night Monday.
(laughs) Definitely!
So the ones you produce for Nas are one minute. That's his specialty…
It's his specialty but it's not every day. About five or six days per month are long videos.
Gotcha – similar to the ones that you put out for Project Nightfall?
Yes, I believe that's the main reason why I joined the team, to make Nas more capable of making long videos because he has so much work. I can't imagine him working on what he does and editing long videos on top of it all the time – that's so much work.
Can you tell us a little bit about the difference between making the longer videos and the shorter videos in terms of your process? What work – before and after the video – is different for making a short video and a longer one?
Well I think almost every element of a long video is harder to be made than short videos because you need to grab attention of an audience for much longer. You need to script a longer video, so you have more to say but it's easy to be boring over the words. The editing takes at least 3x longer. Just the subtitles themselves take 70-80 minutes to create. It's definitely a different process, but some long videos, they come easier because if you discuss a topic that's around one location, that's around one concept, you record everything at once, so it can be almost as easy as the short videos, but most of the time there's way more work involved in long format.
But you don't seem like a person who's afraid of work. So I don't think the work is going to be the thing that… I want to ask you, which one do you prefer more – the one minute or the longer ones? And I don't think that how much work goes into is probably the answer or the determining factor for you.
I think it's the longer ones without a doubt, but if we would be making long videos every single day, we wouldn't be on Earth anymore. (laughs) We would be long gone. The editing really take so much work. When I make videos for my channel or we make long videos for Nas, it's always the extra work, which I'm feeling on me right now because we had a long video yesterday that's about to go out in an hour or too.
During the rest of the interview, we discussed Agon's specific strategies for creating viral videos – from topic selection and script writing to equipment and video editing. Agon revealed how he structures the first 20 seconds of each video to instantly capture attention, engage the viewer, and bring them into the conversation. It's an absolutely epic interview and I personally learned a lot from Agon about creating attention grabbing videos that I'll be incorporating into my own videos on Travel is Life.
And of course, don't forget to follow Project Nightfall, Nas Daily, and Travel is Life on Facebook.
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Montgomery County school board president files for re-election
Montgomery County Board of Education President Shebra Evans on Friday filed for another four-year term, joining a growing list of candidates for this year's election. Evans was elected in 2016 and is a member of the board's Strategic Planning Committee. She was recently elected by her colleagues to a second consecutive year as the board's president. The Silver Spring resident and former financial analyst has two daughters in MCPS. Evans holds the District 4 seat on the board. (Bethesda)
Middle school students Come to the Table at Garrett College
The eighth grade students from Northern and Southern middle schools attended the recent Come to the Table event at Garrett College, which was a celebration of the 150th anniversary of the Periodic Table of Elements. Students either worked individually or in small groups to complete a box dedicated to an assigned element in the periodic table. The students were to include specific information about the element they were assigned, such as element name, atomic number, symbol, atomic mass, state of matter and information about the element's discovery. (Times-News)
Robotics competition teaches youngsters numerous life skills, including perseverance
Alex Fairgrieve knows that failure can be a good thing. She's learned, through a lot of trial and error, defeat is temporary. Alex, 13, was among 150 students on 20 teams that represented 17 local elementary and middle schools at the First Lego League qualifier on Saturday at Allegany College of Maryland's Bob Kirk Arena. The event, hosted by Robotics and Engineering in Allegany County—Together, Inc., was the first of its kind held in Allegany County. Alex, who was on the Washington Middle School R.E.D. team at the competition, said building a robot to follow commands can be challenging and rewarding. (Times-News)
Howard superintendent's proposed $964 million budget looks to address special education staffing
Howard County schools Superintendent Michael Martirano is proposing an operating budget of $964 million for fiscal 2021 that addresses special education staffing, the health fund deficit and new general education positions. The $964.1 million budget proposal presented at Thursday's Board of Education meeting is 7% larger than this year's adopted spending plan, requesting $670.4 million from the county, $285.6 million from the state — including $7.8 million from the Kirwan Commission — and $8 million from additional sources. (Balt Sun)
Baltimore County school superintendent asks for major increase in budget
Baltimore County School Superintendent Darryl L. Williams is proposing an aspirational budget for next school year that would increase spending by $114 million, including an 11 percent increase for the county share. He acknowledged that the request for additional money might have to be spread over several years, particularly because the state is not expected to boost funds to the county in the coming year. (Balt Sun)
Alzheimer's disease research lab — a potentially $100M project — planned for NIH campus
The National Institute on Aging is seeking proposals to bring a new Alzheimer's disease research center to Montgomery County, a potentially $100 million project. NIA, a division within the National Institutes of Health, is planning a one-story, 24,000-square-foot facility for Alzheimer's disease and related dementias research for the NIH's Bethesda campus. It is intended to facilitate work in understanding and discovering effective treatments for these diseases, according to the agency. (Balt Bus Journal)
Morgan State University looks to add medical school
Morgan State University is looking to bring a medical school to its Baltimore campus through a new partnership. The school's board of regents has authorized President David Wilson to pursue the opportunity to construct a new College of Osteopathic Medicine at Morgan State through a strategic partnership. (Balt Bus Journal)
Ex-patients sue UMMS over alleged use of counterfeit surgical hardware
Fourteen former patients of the University of Maryland Baltimore Washington Medical Center have sued the Glen Burnie hospital and the University of Maryland Medical System (UMMS) in Baltimore Circuit Court, alleging that a doctor implanted counterfeit spinal fusion hardware during surgeries and received hundreds of thousands of dollars in kickbacks from the hardware distributor. (Daily Record)
Firefighters Put Out Toilet Fire At High School In Prince George's County
Two Charles County Public Schools Teachers Win The Lottery
MCPS superintendent challenges accuracy of county report on achievement
Smondrowski files for re-election to Montgomery County school board
Kim Pieper: New tech tool to expose the influence of big business in politics
Posted by Center MD on 05 December 2019
Ransom: LifeBridge Acquisition of Bon Secours is a Win for West Baltimore
Posted by Center MD on 20 November 2019
Ransom: Now is the time to think about your Health Insurance
Ted Venetoulis - Welcome to Baltimore, Mr. President
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Malone: Katrina's Legacy
Community calls for full funding of MCPS budget
School board approves plans for DuFief Elementary School replacement
Visit by Vice President Pence strained budget, but Maryland Republican Party finished its year in the black
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We're proud to bring you an Exclusive reveal of a figure that's surely going to find it's way in to many collections – The R.I.O.T. Commando, thanks to our friends a Fresh Monkey Fiction!
This render of the Urban Infantry Soldier troop builder from Eagle Force Returns looks absolutely amazing and will definitely blend well with your existing Modern Era collection. The R.I.O.T. Commando comes with removable weaponry and gear to help him achieve all of R.I.O.T.'s evil goals!
I know I speak for many when I say we can't wait for the Kickstarter campaign to launch this summer! You can check out more upcoming Eagle Force Returns figure images and join in on the discussion here on the boards after the break!


Not since the late 19th Century has there been a collection of select biographies of Covenanter ministers of the Irish Reformed Presbyterian Church. This definitive volume has been written by 21st Century Covenanters, who have a special interest in the lives of these notable men.
Preachers of The Covenants, records the work of these ministers, who declared not only the precious promises of the Covenant of Grace in Christ Jesus but also that which marks the work of the second Scottish Reformation, with the resulting Covenants and their effect on Ireland and the wider world.
These biographies cover over 300 years of Covenanter history and within their historical context, spiritual lessons for today are explored. Almost all of this work has until now been unpublished or not readily accessible.
The selection displays the interest of the authors giving a distinct cross section of those who have served as Preachers of the Covenants over three centuries.


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WTU Today
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· Big News: Professor Xu Weilin, president of Wuhan Textile University, was elected academician of Chinese Academy of Engineering
· Colorful Campus Life at WTU & Memorable Experience in Wuhan——Farewell to All 2021 International Graduate Students
Big News: Professor Xu Weilin, president of Wuhan Textile University, was elected academician of Chinese Academy of Engineering
2021.11.19 Source: Author:Li Nan Hits:
On November 19th , the Chinese Academy of Engineering announced the list of new academicians in 2021. Professor Xu Weilin, president of Wuhan Textile University, was elected academician of Chinese Academy of Engineering.
Dr. Xu Weilin,
Deputy Party Secretary & President of WTU,
professor & doctoral supervisor, born in Luotian, Hubei, Apr of 1969.
Acted as a teacher of both Sichuan University and Wuhan University of Science and Engineering (the predecessor of Wuhan Textile University), the director of WUSE's Textile Research Institute, assistant to president of WUSE, deputy president of WUSE and the member of its CPC's standing committee, deputy president of WTU and the member of its CPC's standing committee, director of cultivation base of Hubei Provincial New Textile Materials and Advanced Processing Technology, a national key laboratory jointly established by Hubei province and Ministry of Education since February of 2010.
Since October of 2020, Prof. XU has been acting as the president of WTU and deputy secretary of its CPC's standing committee to date. With his main research work in the field of textile materials, he has also been acting as vice chairman of China Textile Engineering Society, chairman of Hubei Provincial Textile Engineering Society, senior member of American Institute of Chemical Engineer (AIChE), senior member of The Fiber Society, U.S., consultant expert of Hubei Provincial People's Government, director of technical commission under Hubei Provincial Fiber Inspection Bureau, council member of Hubei Provincial Youth Scientific & Technological Workers.
From June of 1997 to April 4 of 1999, he was conducting his post-doctoral research in Sichuan University. Since the March of 1999, he has been conducting joint research with The Hong Kong Polytechnic University (HKPU), the Texas State University and the California State University, etc. He has also been presiding over and participating into 30-plus projects, including the national key technology R & D programs, the national sci-tech supporting plans, the "973" national high & new technology fundamental research projects, as well as the scientific research projects supported by National Natural Science Foundation of China. He has been successively awarded the second prize of national technological invention, the first prize of national scientific and technological progress, the first prize of Hubei provincial technological invention. Besides his 140 published papers both at home and abroad to be indexed by SCI, he has also been granted 5 invention patents in US and 58 invention patents in China .
He has been successively awarded such honorary titles as Figure of the Year for China's textile innovation, winner of outstanding achievement granted by The Fiber Society, winner of the 11th Youth Sci-tech Award of China, Winner of Hubei Provincial Prize for Outstanding Distribution, Winner of Sci-tech Innovation Award by Ho Leung Ho Lee Foundation, winner of China Textile Academic Grand Prize, Mulberry & Ramie Scholar, Distinguished Figure with Accomplishments in Textile Industry to commemorate the 40th anniversary of the Reform and Opening Policy in China. Besides the support by National Science Foundation for Distinguished Young Scholars, he has been successively granted such honors as specialized allowance by Hubei Provincial People's Government, winner of Hubei Provincial May 4th Youth Medal, winner of the Best Ten Distinguished Youth in Hubei Province, winner of the May Day Labor Medal by Hubei Province, the Excellent Party Member granted by Hubei Provincial CPC Committee and winner of Specialized Allowance by the State Council of PRC, National Representative of Educational Ethics, winner of National May Day Medal, and winner of National Excellent Labor, etc.
Editor: Li Nan
Multicultural Exchange Forum and International Students' Speech Contest was Held at WTU


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Neuroacanthocytosis refers to a group of inherited genetic disorders resulting in a combination of misshapen red blood cells (acanthocytes) and progressive neurological decline. The neurological presentation can vary widely among diseases and can include shared characteristic features of movement disorders, neuropathy, psychiatric symptoms, neurocognitive degeneration, and seizures. This activity reviews the evaluation and treatment of neuroacanthocytosis and highlights the role of the interprofessional team in the care of patients with this condition.
Describe the etiology of neuroacanthocytosis.
Review the appropriate evaluation of neuroacanthocytosis.
Outline the treatment options available for neuroacanthocytosis.
Summarize the importance of an interprofessional team to enhance the delivery of care and improve outcomes for patients affected by neuroacanthocytosis.
Neuroacanthocytosis refers to a group of inherited genetic disorders resulting in a combination of misshapen red blood cells (acanthocytes) and progressive neurological decline.[1] The neurological presentation can vary widely among diseases and can include shared characteristic features of movement disorders, neuropathy, psychiatric symptoms, neurocognitive degeneration, and seizures.[2] Specific diseases are many, including chorea-acanthocytosis (ChAc),[3] McLeod syndrome (MLS),[4] Huntington like-disease 2 (HDL2),[5] pantothenate kinase-associated neurodegeneration (PKAN, also known as Hallervorden Spatz disease),[6][7] HARP Syndrome (considered part of the PKAN spectrum consisting of hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration), abetalipoproteinemia (ABL),[8] hereditary hypobetalipoproteinemia (HHBL),[9] and aceruloplasminemia.[10][11] The two core conditions are chorea-acanthocytosis and McLeod Syndrome. Each neuroacanthocytosis disorder is extremely rare, with a prevalence of less than 1 to 3 per 1,000,000 individuals for PKAN or fewer than 100 cases ever reported in the case of ABL.
Neuroacanthocytosis syndromes are caused by a variety of genetic mutations that are inherited in several different patterns, with the most common being autosomal recessive (see Tables 1 & 2). Other syndromes such as McLeod syndrome are inherited in an X-linked recessive pattern, whereas Huntington like-disease 2 and hereditary hypobetalipoproteinemia are inherited in autosomal dominant and codominant patterns, respectively. HDL2 directly results from trinucleotide expansions of JPH3 very similarly to Huntington disease with patients experiencing intergenerational disease anticipation based on the extent of genetic expansion. Many of these diseases vary in genetic penetrance and phenotypic manifestations.[3][4][5][6][8][9][10]
Each neuroacanthocytosis syndrome is exceedingly rare (see Table 1). Several populations have been identified as having higher prevalence compared to the global population. Examples include HDL2 demonstrating increased reported cases among individuals of African heritage and PKAN occurring more often in small pockets in the Netherlands and the Dominican Republic.[5]
The pathophysiology of these syndromes is unique to each and can vary widely in phenotypic disease manifestation (see Table 2). The direct cellular mechanisms of several syndromes such as PKAN, aceruloplasminemia, and diseases of lipoproteins are understood and described in the current literature. These syndromes tend to have better outcomes either due to milder disease progression or treatment modalities that prevent significant mortality and morbidity.[6][8][9][10] Other diseases such as ChAc, MLS, and HDL2 are not well understood despite the identification of involved genes.[3][4][5] These diseases tend to be much more chronically debilitating and are not uniformly responsive to attempted treatments that have been sparsely reported.
History and Physical
Nearly all patients affected by neuroacanthocytosis syndromes will experience the eventual onset of progressive abnormalities in movement (usually ataxia or hyperkinetic movements) with a neurocognitive decline and behavioral changes (see Table 3). Each specific disease, however, may present with symptoms and comorbidities unique to the disease. If the clinician possesses significant clinical suspicion of a neuroacanthocytosis syndrome, a thorough physical exam is required. This would include a complete physical and neurological examination, including reflexes, cranial nerves, gait, muscle strength, and mental status exams.
A clear history of progressive neurological, neuromuscular, or neuropsychiatric symptoms that are not consistent with other more common diseases plays an integral role in identifying these rare syndromes as possible diagnoses. The acquisition of prior records, family history, collateral history, and any prior genetic testing may prove instrumental in establishing accurate differential diagnoses and choosing clinically appropriate diagnostic modalities for further evaluation.
For many of these syndromes, the clinical symptoms will often prompt the use of additional diagnostic modalities that are instrumental in establishing a correct diagnosis (see Table 4). Such modalities include magnetic resonance imaging (MRI), or computed tomography (CT) scans to assess neurological involvement in the cerebral or spinal nervous tissues. Additionally, laboratory testing of serum samples may be useful in ruling out some diseases while providing confirmatory data for others, as in the case of the diseases of lipoproteins (ABL and HHBL) or aceruloplasminemia. For most neuroacanthocytosis syndromes, there are either no clear diagnostic criteria (e.g., ChAc, ABL, and HHBL) or genetic testing to identify diseases that may otherwise be indistinguishable from other syndromes (e.g., HDL2).
Treatment / Management
There is no cure or definitive treatment for several of the neuroacanthocytosis syndromes, such as ChAc and MLS (see Table 5).[12] With the exception of ABL, HHBL, and aceruloplasminemia, the goals of management generally are to:
1) Treat symptomatically
2) Slow the development of progressive symptoms
3) Evaluate for and prevent where possible serious causes of morbidity and mortality such as ophthalmic involvement, metabolic/hormonal imbalances, seizures, cardiac involvement, and status dystonicus.
Interprofessional treatment teams have been advocated as the ideal approach in caring for patients who likely have complex and significant symptoms that run the gamut of neurological to psychiatric to multiple organ systems.[12]
Consultation by medical specialists in neurology, psychiatry, neuropsychiatry, ophthalmology, or clinical genetics may be appropriate in identifying, evaluating, and managing patients diagnosed with neuroacanthocytosis syndromes (see Table 6).
The differential diagnoses for these rare syndromes are many and sometimes may be indistinguishable from other disease entities without the appropriate radiological, laboratory, or genetic workup (see Table 7).
Pertinent Studies and Ongoing Trials
Due to the extreme rarity of these syndromes, there have been no randomized control trials or experimental treatment studies assessing the efficacy of diagnostic or treatment modalities.[12][13][14] Information regarding diagnostic criteria and possible treatments have been largely developed from the aggregation of case reports and case series.[12]
Toxicity and Side Effect Management
There are several side effects to keep in mind for several specific syndromes and their associated management (see Table 5). For example, antiepileptic drugs (AEDs) such as carbamazepine and lamotrigine should be avoided in patients with ChAc due to the worsening of involuntary movements.[3] Conversely, long-term use of benzodiazepines should be avoided as an AED in patients with McLeod syndrome due to potential negative effects on the neuromuscular system. Additionally, dopamine antagonists or tetrabenazine should be avoided due to increased risk of extrapyramidal symptoms (EPS) in MLS patients.[4]
Another consideration for MLS patients is to avoid heterologous blood product transfusions due to an increased risk of adverse transfusion reactions. Case reports have suggested avoiding alpha-tocopherol and idebenone in treating the neuromuscular symptoms of patients with PKAN due to anecdotal evidence suggesting worsening of symptoms.[6] Finally, patients should avoid iron supplementation or other sources of exogenous iron due to the iron accumulation inherent in the disease.[10]
The prognosis for these syndromes is variable. Syndromes such as ChAc, MLS, typical PKAN, and HDL2 are known to be chronic and progressive, often resulting in complications of dysarthria such as malnutrition and aspiration pneumonia with eventual death (see Table 8). In some cases, complicating symptoms such as seizures, cardiac arrhythmias, cardiomyopathy, and status dystonicus may cause premature death. On the other hand, the mortality and progression of aceruloplasminemia, ABL, and HHBL are heavily influenced by appropriate management with chelating agents and fat-soluble vitamin supplementation (respectively) with patients enjoying a typical lifespan if managed appropriately.[8][9][10]
Many of the complications arising from neuroacanthocytosis syndromes derive from neuromuscular deficits or neurocognitive decline (see Table 3). Neuromuscular symptoms such as chorea, ataxia, myopathy, dystonia, loss of dorsal column, or spinocerebellar spinal tracts can result in gait disturbances and inability to participate in ADLs. Additional progressive cognitive deficits or personality changes (including increased impulsivity, aggression, or psychiatric symptoms) can further complicate care for patients diagnosed with a neuroacanthocytosis syndrome. Several complications can be life-threatening, including seizures, cardiac arrhythmias, cardiomyopathy, status dystonicus, and psychiatric comorbidities such as suicidality.
Ophthalmological complications such as retinal degeneration and retinopathy are commonly described in cases of PKAN, ABL, HHBL, and aceruloplasminemia. In the case of several metabolically driven diseases such as ABL, HHBL, and aceruloplasminemia, multiple organ systems can be involved resulting in anemia, diabetes mellitus, cardiomegaly, hepatosplenomegaly, and hypothyroidism.
Deterrence and Patient Education
Genetic counseling plays an important role in the management as well as appropriate evaluation and education for both the patient and involved family members. Consultation with a genetic counselor and clinical geneticist can provide important clinical information such as genotypic and phenotypic characteristics of the disease, possible disease progression, and the likelihood of disease occurring in relatives or offspring.[1]
Enhancing Healthcare Team Outcomes
Recent literature advocates interprofessional team-based care as the ideal approach in caring for patients diagnosed with neuroacanthocytosis syndromes due to the severity and chronic progression of symptoms as well as possible development of severe medical comorbidity.[12] Such a care team would likely consist of the patient's primary care clinician, neurologist, clinical geneticist (or genetic counselor), and several other therapeutic modalities (see Table 5). Providers may seek additional care in consultation with specialists in psychiatry, ophthalmology, and cardiology in diseases such as MLS, PKAN, and ABL/HHBL. The extreme rarity of these syndromes significantly limits evidence-based treatments. Patients with these syndromes may require involved and prolonged team-based care to improve symptoms and prevent the development of serious medical complications.
Table 1: Epidemiology of Neuroacanthocytosis Syndromes Table 2: Genetics of Neuroacanthocytosis Syndromes
Contributed by Joshua Feriante DO, MBA
Table 3: Clinical Manifestations of Neuroacanthocytosis Syndromes
Table 4: Diagnostic Testing for Neuroacanthocytosis Syndromes
Table 5: Management, Preventive Measures, and Multi-disciplinary Team Involvement for Neuroacanthocytosis Syndromes Table 6: Preventive Measures and Multi-disciplinary Team Involvement for Neuroacanthocytosis Syndromes
Table 7: Differential Diagnoses for Neuroacanthocytosis Syndromes Table 8: Prognoses of Neuroacanthocytosis Syndromes
Joshua Feriante
Article Editor:
Vikas Gupta
Jung HH,Danek A,Walker RH, Neuroacanthocytosis syndromes. Orphanet journal of rare diseases. 2011 Oct 25; [PubMed PMID: 22027213]
Shah JR,Patkar DP,Kamat RN, A case of McLeod phenotype of neuroacanthocytosis brain MR features and literature review. The neuroradiology journal. 2013 Feb [PubMed PMID: 23859162]
Velayos Baeza A,Dobson-Stone C,Rampoldi L,Bader B,Walker RH,Danek A,Monaco AP, Chorea-Acanthocytosis 1993; [PubMed PMID: 20301561]
Jung HH,Danek A,Walker RH,Frey BM,Gassner C, McLeod Neuroacanthocytosis Syndrome 1993; [PubMed PMID: 20301528]
Anderson DG,Krause A,Margolis RL, Huntington Disease-Like 2 1993; [PubMed PMID: 20301701]
Gregory A,Hayflick SJ, Pantothenate Kinase-Associated Neurodegeneration 1993; [PubMed PMID: 20301663]
Razmeh S,Habibi AH,Orooji M,Alizadeh E,Moradiankokhdan K,Razmeh B, Pantothenate kinase-associated neurodegeneration: Clinical aspects, diagnosis and treatments. Neurology international. 2018 Mar 30; [PubMed PMID: 29844889]
Burnett JR,Hooper AJ,Hegele RA, Abetalipoproteinemia 1993; [PubMed PMID: 30358967]
Welty FK, Hypobetalipoproteinemia and abetalipoproteinemia. Current opinion in lipidology. 2014 Jun; [PubMed PMID: 24751931]
Miyajima H,Hosoi Y, Aceruloplasminemia 1993; [PubMed PMID: 20301666]
Marchi G,Busti F,Lira Zidanes A,Castagna A,Girelli D, Aceruloplasminemia: A Severe Neurodegenerative Disorder Deserving an Early Diagnosis. Frontiers in neuroscience. 2019; [PubMed PMID: 31024241]
Walker RH, Management of Neuroacanthocytosis Syndromes. Tremor and other hyperkinetic movements (New York, N.Y.). 2015; [PubMed PMID: 26504667]
Vroegindeweij LHP,Boon AJW,Wilson JHP,Langendonk JG, Effects of iron chelation therapy on the clinical course of aceruloplasminemia: an analysis of aggregated case reports. Orphanet journal of rare diseases. 2020 Apr 25; [PubMed PMID: 32334607]
Junaid Z,Patel K, Abetalipoproteinemia 2020 Jan; [PubMed PMID: 30020727]
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What are the cases in which metastability occurs?
So how do I avoid metastability?
In reality, one cannot avoid metastability and increased clock-to-Q delays in synchronizing asynchronous inputs, without the use of tricky self-timed circuits. So a more appropriate question might be "How do I tolerate metastability?"
In the simplest case, designers can tolerate metastability by making sure the clock period is long enough to allow for the resolution of quasi-stable states and for the delay of whatever logic may be in the path to the next flip-flop. This approach, while simple, is rarely practical given the performance requirements of most modern designs.
The most common way to tolerate metastability is to add one or more successive synchronizing flip-flops to the synchronizer. This approach allows for an entire clock period (except for the setup time of the second flip-flop) for metastable events in the first synchronizing flip-flop to resolve themselves. This does, however, increase the latency in the synchronous logic's observation of input changes.
Neither of these approaches can guarantee that metastability cannot pass through the synchronizer; they simply reduce the probability to practical levels.
In quantitative terms, if the Mean Time Between Failure (MTBF) of a particular flip-flop in the context of a given clock rate and input transition rate is 33.33 seconds then the MTBF of two such flip-flops used to synchronize the input would be (33.33* 33.33) = 18.514 Minutes. Well I have taken the worst flip-flop ever designed in history of man kind :-). The figure below shows how to connect two flip-flops in series to achieve this and also the resultant MTBF.
Cascade two or three D-Flip-Flops (two or three stages synchronizer).
Thomas J. Chaney, "Measured Flip-Flop Responses to Marginal Triggering", IEEE Transactions on Computers, Vol. C-32. No. 12, December 1983, pp.1207-1209.
Lindsay Kleeman and Antonio Cantoni, "On the Unavoidability of Metastable Behavior in Digital Systems", IEEE Transactions on Computers, Vol. C-36. No. 1, January 1987, pp.109-112.
Lindsay Kleeman and Antonio Cantoni, "Can Redundancy and Masking Improve the Performance of Synchronizers?", IEEE Transactions on Computers, Vol. C-35, No. 7, July 1986, pp.643-646.
M. Valencia, M. J. Bellido, J. L. Huertas, A. J. Acosta, and S. Sanchez-Solano, "Modular Asynchronous Arbiter Insensitive to Metastability. IEEE Transactions on Computers, 44(12):1456-1461, December 1995.