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http://scigraph.springernature.com/pub.10.1007/s00221-017-5044-y
Cortico–thalamic disconnection in a patient with supernumerary phantom limb View Full Text
Ontology type: schema:ScholarlyArticle
Clémence Bourlon, Marika Urbanski, Romain Quentin, Christophe Duret, Eric Bardinet, Paolo Bartolomeo, Alexia Bourgeois
Supernumerary phantom limb (SPL) designates the experience of an illusory additional limb occurring after brain damage. Functional neuroimaging during SPL movements documented increased response in the ipsilesional supplementary motor area (SMA), premotor cortex (PMC), thalamus and caudate. This suggested that motor circuits are important for bodily related cognition, but anatomical evidence is sparse. Here, we tested this hypothesis by studying an extremely rare patient with chronic SPL, still present 3 years after a vascular stroke affecting cortical and subcortical right-hemisphere structures. Anatomical analysis included an advanced in vivo reconstruction of white matter tracts using diffusion-based spherical deconvolution. This reconstruction demonstrated a massive and relatively selective disconnection between anatomically preserved SMA/PMC and the thalamus. Our results provide strong anatomical support for the hypothesis that cortico-thalamic loops involving motor-related circuits are crucial to integrate sensorimotor processing with bodily self-awareness. More... »
Experimental Brain Research
FOR: Neurosciences
FOR: Medical And Health Sciences
MESH: Female
MESH: Humans
MESH: Middle Aged
MESH: Motor Cortex
MESH: Perceptual Disorders
MESH: Phantom Limb
MESH: Stroke
MESH: Thalamus
MESH: White Matter
Pitié-Salpêtrière Hospital
National Institute of Neurological Disorders and Stroke
Institut du Cerveau et de la Moelle Épinière
University of Geneva
From Grant
Brain & Behaviour Interdisciplinary Research
http://dx.doi.org/10.1007/s00221-017-5044-y
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376 ″ ″ Service de Médecine et de Réadaptation gériatrique et neurologique, Hôpitaux de Saint-Maurice, 94410, Saint-Maurice, France
377 ″ ″ Unité de Neurorééducation, Centre de Rééducation Fonctionnelle Les Trois Soleils, 77310, Boissise Le Roi, France
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390 ″ schema:name Laboratory for Behavioral Neurology and Imaging of Cognition, Neuroscience Department, University of Geneva, Geneva, Switzerland


text:
Hounslow icon Mo Farah heads to Rio Olympics in fine form after London Anniversary Games triumph
The 33-year-old ran the fastest 5,000m of the year so far on his return to the scene of his London 2012 heroics
Hayley Fox
Winner: Mo Farah of Great Britain goes clear (Image: Christopher Lee/Getty Images)
Hounslow icon Mo Farah stormed to victory at the London Anniversary Games where he ran the fastest 5,000m of the year to head to Rio in great form.
The 33-year-old crossed the line in 12 minutes 59.29, dominating the same track where he claimed Olympic gold at the 5,000m and 10,000m events in 2012, which he'll be out to defend in Brazil next month.
Farah, running his first competitive 5,000m of 2016, praised the amazing support of the crowd at the stadium.
He added: "I love this track, it has so much meaning to me. Many athletes dream of the Olympics, but to do it in your hometown - it's amazing.
"I just wanted to go for it. It's great to win before Rio."
Farah beat fellow Briton and Rio hopeful Andrew Butchart who came second, more than 15 seconds slower, with American Bernard Lagat in third place.
He said: "I am in good shape and I just have to keep my feet on the ground. In two weeks anything could happen - I've just got to stay cool."
Britain's Mo Farah does his trademark 'mobot' gesture as he celebrates winning the men's 5,000 metres (Image: ADRIAN DENNIS/AFP/Getty Images)
Mo Farah of Team GB (Image: Alex Morton/Getty Images)
Farah , who has a gold-painted post box in Isleworth in his honour, is bidding to become only the second man in history, after Finnish legend Lasse Viren in 1976, to retain two Olympic distance titles.
He said: "One thing you can't forget is it's harder for me to defend an Olympics. The rest of the guys have had four years of preparation so anything could happen.
"They haven't managed it yet but I'm going to have three Ethiopians, three Kenyans, three Ugandans. They're going to try and do anything to beat me."
Farah, who won two gold medals in the World Championships in Beijing last year, will now head back to Font Romeu, in the French Pyrenees, for last-minute altitude training before heading off to Rio.
Is Mo Farah Britiain's greatest ever sportsman?
0+ VOTES SO FAR
BBCWhen is the 2022 Super Bowl and how to watch it in the UK?Super Sunday is back next month
Winter OlympicsWhen do the 2022 Winter Olympics start and where are they being held this year?Several Covid-19 safety measures will be in place to protect athletes and staff.
When is the 2022 Super Bowl and how to watch it in the UK?
BBCSuper Sunday is back next month
From £18 burger and chips to £2.50 pies - the wild differences between London's football food prices
Grassroots FootballThe jury is out for which club provides the best food on matchday and the price they charge for this
'I beat anorexia and bulimia - now I'm a champion female powerlifter and I can lift the weight of a motorbike'
Real LifeSophia Ellis only started powerlifting three years ago, but now she can lift the equivalent of a lion, alligator or grizzly bear
Darts fans in stitches as commentator reveals Raymond van Barneveld's manager's brilliantly 'rude' name
Darts'Bendy c*ck' was trending at number one on Twitter last night

redpajama_set_name: RedPajamaCommonCrawl


The house is located in a great spot, only a 5 minute drive from the beach and just off Beaumont street with all its bars and cafes. The house is modern and spacious. The terrace is furnished, however, you will need to bring your own bedroom furniture. The bedroom has a built in wardrobe and it's own private balcony.
You will be living with 2 males aged 25 and 21. We are both tidy and easy to get along with. We both work with secure jobs. Looking for someone who is tidy and good company. If you're interested feel free to send us a message.


Continuing on in my series with Rustic Thread boutique, let's talk transitioning to Fall. I touched on the subject briefly yesterday, by pairing a maxi with ankle booties, and am kicking things up a notch today by adding in a faux fur vest.
Because Fall weather is so unpredictable, my motto is layer, layer, layer! A light weight tunic may be perfectly fine for the day, but as the day turns to night, the temp drops quickly in these parts, so keeping a heavy vest handy is a safe bet to combat the elements.
Now, let's talk shoes. I originally planned to style this outfit with these DV by Dolce Vita ankle booties (below) but loved the gold slides version so much that I decided to post them both and let you be the judge.
I love that faux fur vest and how you styled it with the tunic! Such a great look!
Love the fresh cream color palette here!!
I LOVE fur for the fall--and I am not going to lie--I think I like the birk style shoes the best :) Its such a great look!
LOVEEEE this look! The fur vest is gorgeous!
Great look into fall! Love the fall fur vest and those beautiful booties!
That fur vest is absolutely beautiful! I love the colors, it's perfect. I like the booties better with this outfit than the sandals, but both look great!
Both look great, but I think I like the booties best. That vest is beautiful!
Such an unexpected combination, yet it works perfectly!
I love the look with the booties. I love love love this vest! It's great!
Nice to meet you! Stunning outfit and agree with the layering advice! Layers are perfect for spring and fall aren't they?
The different textures work beautifully together and the fur vest is gorgeous. Feminine and chic. I love both looks but for me the boots edge it just slightly!
Love love love this look! It's perfect and you are gorgeous!


Boost Mobile: No signs of slowing down for Chad Reed at the Supercross final in Las Vegas, Nevada.
What happens in Vegas doesn't always stay in Vegas. Aaron Plessinger took home the 250 West title, proposed to his girlfriend, and was sporting a gladiator helmet at the post-race press conference.
Zach successfully defended his 250 SX title, on a night where Husqvarna took home two number one plates.
After a tough Salt Lake City round, we caught up with Jason Anderson before the Supercross season finale here in Las Vegas.
Listen in to the 450 podium (Musquin, Anderson, and Wilson) after Marvin Musquin took home one million dollars for winning all three mains at the Monster Energy Cup.


text:
Q: QComboBox with autocompletion works in PyQt4 but not in PySide I've got a combo box with a custom completer that worked fine in PyQt4, but isn't working in PySide.
I have verified that the new completer is replacing the QComboBox's built in completer because inline completion is no longer occurring.  However when run with PySide, the completer doesn't popup with a filtered list of options.
I've also tried ensuring that all text is all str or all unicode to avoid differences between the PyQt API 1 with QStrings and PySide's use of Python unicode types.  Changing the text types has had no effect on either PyQt or PySide's behavior (PyQt keeps working, PySide doesn't work).
Here is my code:
from PySide import QtCore
from PySide import QtGui

#from PyQt4 import QtCore
#from PyQt4 import QtGui

class AdvComboBox(QtGui.QComboBox):
    def __init__(self, parent=None):
        super(AdvComboBox, self).__init__(parent)

        self.setFocusPolicy(QtCore.Qt.StrongFocus)
        self.setEditable(True)

        # add a filter model to filter matching items
        self.pFilterModel = QtGui.QSortFilterProxyModel(self)
        self.pFilterModel.setFilterCaseSensitivity(QtCore.Qt.CaseInsensitive)
        self.pFilterModel.setSourceModel(self.model())

        # add a completer, which uses the filter model
        self.completer = QtGui.QCompleter(self.pFilterModel, self)
        # always show all (filtered) completions
        self.completer.setCompletionMode(QtGui.QCompleter.UnfilteredPopupCompletion)

        self.setCompleter(self.completer)

        # connect signals

        def filter(text):
            print "Edited: ", text, "type: ", type(text)
            self.pFilterModel.setFilterFixedString(str(text))

        self.lineEdit().textEdited[unicode].connect(filter)
        self.completer.activated.connect(self.on_completer_activated)

    # on selection of an item from the completer, select the corresponding item from combobox
    def on_completer_activated(self, text):
        print "activated"
        if text:
            print "text: ", text
            index = self.findText(str(text))
            print "index: ", index
            self.setCurrentIndex(index)

    # on model change, update the models of the filter and completer as well
    def setModel(self, model):
        super(AdvComboBox, self).setModel(model)
        self.pFilterModel.setSourceModel(model)
        self.completer.setModel(self.pFilterModel)

    # on model column change, update the model column of the filter and completer as well
    def setModelColumn(self, column):
        self.completer.setCompletionColumn(column)
        self.pFilterModel.setFilterKeyColumn(column)
        super(AdvComboBox, self).setModelColumn(column)

if __name__ == "__main__":
    import sys

    app = QtGui.QApplication(sys.argv)

    combo = AdvComboBox()

    names = ['bob', 'fred', 'bobby', 'frederick', 'charles', 'charlie', 'rob']

    # fill the standard model of the combobox
    combo.addItems(names)
    combo.setModelColumn(0)
    combo.resize(300, 40)
    combo.show()

    sys.exit(app.exec_())

A: I figured it out while writing the question...
It appears that while the PySide QCompleter documentation lists an option to initialize the QCompleter with a model and a parent, it isn't actually working.
The solution is to set the model of the completer after it is initialized.
Here is the working code:
from PySide import QtCore
from PySide import QtGui

class AdvComboBox(QtGui.QComboBox):
    def __init__(self, parent=None):
        super(AdvComboBox, self).__init__(parent)

        self.setFocusPolicy(QtCore.Qt.StrongFocus)
        self.setEditable(True)

        # add a filter model to filter matching items
        self.pFilterModel = QtGui.QSortFilterProxyModel(self)
        self.pFilterModel.setFilterCaseSensitivity(QtCore.Qt.CaseInsensitive)
        self.pFilterModel.setSourceModel(self.model())

        # add a completer
        self.completer = QtGui.QCompleter(self)
        #Set the model that the QCompleter uses
        # - in PySide doing this as a separate step worked better
        self.completer.setModel(self.pFilterModel)
        # always show all (filtered) completions
        self.completer.setCompletionMode(QtGui.QCompleter.UnfilteredPopupCompletion)

        self.setCompleter(self.completer)

        # connect signals

        def filter(text):
            print "Edited: ", text, "type: ", type(text)
            self.pFilterModel.setFilterFixedString(str(text))

        self.lineEdit().textEdited[unicode].connect(filter)
        self.completer.activated.connect(self.on_completer_activated)

    # on selection of an item from the completer, select the corresponding item from combobox
    def on_completer_activated(self, text):
        print "activated"
        if text:
            print "text: ", text
            index = self.findText(str(text))
            print "index: ", index
            self.setCurrentIndex(index)

    # on model change, update the models of the filter and completer as well
    def setModel(self, model):
        super(AdvComboBox, self).setModel(model)
        self.pFilterModel.setSourceModel(model)
        self.completer.setModel(self.pFilterModel)

    # on model column change, update the model column of the filter and completer as well
    def setModelColumn(self, column):
        self.completer.setCompletionColumn(column)
        self.pFilterModel.setFilterKeyColumn(column)
        super(AdvComboBox, self).setModelColumn(column)

if __name__ == "__main__":
    import sys

    app = QtGui.QApplication(sys.argv)

    combo = AdvComboBox()

    names = ['bob', 'fred', 'bobby', 'frederick', 'charles', 'charlie', 'rob']

    # fill the standard model of the combobox
    combo.addItems(names)
    combo.setModelColumn(0)
    combo.resize(300, 40)
    combo.show()

    sys.exit(app.exec_())

redpajama_set_name: RedPajamaStackExchange


text:
Q: jmeter http request no value, but wrong name I create a jmeter http request
with parameter name & value.
While the test result is no value only the parameter names.(parameter names are wrong :(
parameters config
error result
POST http://localhost:8080/aqnu/loginsys

POST data:
200117003200117003

Cookie Data:
JSESSIONID=438A7FCE7211763AFFF57F89F5A9FCB3

Request Headers:
Connection: keep-alive
Referer: http://localhost:8080/aqnu/login
Accept-Language: zh-CN,zh;q=0.9,en;q=0.8,zh-TW;q=0.7
Origin: http://localhost:8080
DNT: 1
Accept: text/html,application/xhtml+xml,application/xml;q=0.9,image/webp,image/apng,*/*;q=0.8
Upgrade-Insecure-Requests: 1
Content-Type: application/x-www-form-urlencoded
Cache-Control: max-age=0
Accept-Encoding: gzip, deflate, br

A: *

*It might be the case with the parameters themselves, i.e. if you copied and pasted them from some source the parameters may include non-printable special characters like line breaks therefore JMeter fails to properly parse them in HTML mode. Try switching to Raw and see how does your request look like there

*If the cause is different unfortunately we will not able to help without seeing the logs. If you want to check it out yourself or update the question with the logs:

*

*Add the next lines to log4j2.xml file
<Logger name="org.apache.jmeter.protocol.http" level="debug" />
<Logger name="org.apache.http" level="debug" />
<Logger name="org.apache.http.wire" level="error" />

These lines will increase JMeter logs verbosity for HTTP protocol

*Restart JMeter to pick up the changes

*Search for your request parameters in jmeter.log file an see how do they look like.


I am still making the socks on the right. After spending so much on the wool I am determined to finish them...... One day.
The socks on the left were bought at a local Embroiderers Guild show. The lady selling them was raising money for Shelter Box - they are very lovely and soft to wear and apparently the colour from Monet's Garden!
Pop over and have a look at the interesting stuff and places Annabelle has been to.
I don't really get on with knitting but I wish I did when I see your socks, which are beautiful.
Lovely coloured socks! (both of them)and shelter box is a great charity. I haven't even cast on yet but hopefully will tomorrow.
Knitting socks, amazing! I am always in awe of people starting and finishing!
I just came here from Annabelle Serendipity and love your blog...I will be back.


text:
Anthropology / Sociology
Trade Catalogues
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Any Price (50) $100-499 (1) $500-4,999 (26) $5,000-19,999 (16) $20,000 and up (7)
Sign up for notifications as we get new books.
I'd like to be notified as books on other topics come in.
Catalogue 143: Literature Selections from Waiting for Godot Books
For more than forty years the rare booksellers Gary Oleson and Francine Ness operated privately as Waiting for Godot Books. They specialized in many areas of literature: American, British, Irish, Latin-American, Native American, as well as African-American and Women's literature and history.
We are pleased to present Catalogue 143: Literature, a selection from the inventory of Waiting for Godot Books with highlights such as Percy Shelley's Essays, Letters from Abroad, Translations, and Fragments, inscribed by Mary Shelley, and a corrected typescript of Truman Capote's The House of Flowers.
Author Title Highest Price Lowest Price Most Recent Publisher Newest Published Oldest Published Items with Photo
NextNext page
Abbey, Edward.
Signed Photograph of Edward Abbey.
Signed. Signed photograph. Framed. Matted to 6.5" x 9". Unexamined out of the frame but appears to be fine, other than a small scratch on the pelexiglass covering the image. Signed in lower margin "Edward Abbey". Three-quarter view of Abbey, who stands in a bookstore with one with one hand..... Read More about Signed Photograph of Edward Abbey
'No one has ever given me such a boost'
Auster, Paul.
Group of Correspondence to Charles Simic, comprising 1 Typed Letter, signed, and 10 Autograph Letters and Notes, signed, 1973-1982.
Var, France; Berkeley, Brooklyn, etc: 1973-1982. 'No one has ever given me such a boost'. Correspondence from poet and novelist Paul Auster to poet Charles Simic early in Auster's career, evolving from an initial formal typed letter, expressing admiration and seeking a contribution to Living Hand, to a steady and..... Read More about Group of Correspondence to Charles Simic, comprising 1 Typed Letter, signed, and 10 Autograph...
Beckett, Samuel.
Endgame. A Play in One Act followed by Act Without Words. A Mime for One Player.
New York: Grove Press, Inc, (1958). First American edition, clothbound trade issue. First American edition, clothbound trade issue. Translated from the French by the author. Octavo. 92pp. Full cloth. Binding is very slightly tanned at base and crown of spine, else a near fine, bright copy, in publisher's near fine..... Read More about Endgame. A Play in One Act followed by Act Without Words. A Mime for One Player
Beckett's Masterpiece, Inscribed
Waiting for Godot.
New York: Grove Press, (1954). First edition in English (translated by the author), preceding the British edition. Beckett's Masterpiece, Inscribed. First edition in English (translated by the author), preceding the British edition. Fine in fine dustwrapper with slightest toning at the spine and a tiny tear, housed in a quarter..... Read More about Waiting for Godot
Barney Rosset's Copy
Watt.
New York: Grove Press, (1959). First American edition. Copy number 2 of 4 numbered copies marked hors commerce and signed by Beckett. Barney Rosset's Copy. First American edition. Quarter cloth gilt and paper covered boards. Fine, issued without printed dust jacket. This is copy number 2 of 4 numbered copies..... Read More about Watt
SIGNED BY BIERCE
Bierce, Ambrose.
The Cynic's Word Book.
New York: Doubleday, Page, [October], 1906. First edition, BAL state A (no priority). SIGNED BY BIERCE. First edition of a work (comprising definitions for A through L) that later gained fame as The Devil's Dictionary (a complete alphabet was published in 1911 as volume VII of the Collected Works). Bierce's..... Read More about The Cynic's Word Book
(Brecht Source) [van der Veer, Ethel].
Circle of Chalk. (Written and produced probably in the 13th or 14th century A.D.) [Caption title].
[n.d., ca. 1930s?]. My station in life Is that of a clerk. But privately There are two things I love Surpassingly: Good wine And the women Of other men. Acting script of the Ethel van der Veer translation of a Chinese play, Circle of Chalk, which tells a tale of..... Read More about Circle of Chalk. (Written and produced probably in the 13th or 14th century A.D.) [Caption title
Capote, Truman.
The House of Flowers. Corrected Typescript.
August 3, 1950. Published: Mademoiselle, April 1951. Collected in Breakfast at Tiffany's (1958). The Mademoiselle magazine file copy of the typescript, with editorial corrections, of Truman Capote's acclaimed story, "House of Flowers", the story of Haitian prostitute Ottilie, beautiful and strong-willed yet doomed by circumstances. With a short typed note..... Read More about The House of Flowers. Corrected Typescript
Cather, Willa Sibert.
O Pioneers!
Boston: Houghton Mifflin, [June], 1913. First Edition, first issue with date on title-page and copyright page. Read More about O Pioneers!
Collins, Wilkie.
The Haunted Hotel. A Mystery of Modern Venice.
Toronto: Rose-Belford Publishing Company, 1878. First edition, preceding the English edition. Published in October, 1878. Collins' novel of intrigue and experimental chemistry was serialized in Belgravia from June to November 1878. This Canadian printing precedes the Chatto & Windus edition, published in two volumes in 1879. Read More about The Haunted Hotel. A Mystery of Modern Venice
INSCRIBED
Didion, Joan.
Play It As It Lays.
New York: Farrar, Straus & Giroux, (1970). First edition. INSCRIBED. First edition. Slightly cocked spine, bumped corners, and toning on the board edges else very good in a very good spine-faded dust jacket with rubbing and creasing. Inscribed by the author. Read More about Play It As It Lays
[Douglas, Norman].
[Offprint]: Zur Fauna Santorins [drop title]. [At head of title:] Separat-Abdruck aus dem »Zoologischen Anzeiger« No. 407. 1892.
London / [Leipzig]: [Leipzig]: Zoollogischen Anzeigers, 1892. First edition. The first separately published work by Norman Douglas, an offprint limited to "about 50 copies for private distribution" and preceded only by periodical appearances. Written by Norman Douglas following a brief visit to the island of Santorin in early May of..... Read More about Offprint]: Zur Fauna Santorins [drop title]. [At head of title:] Separat-Abdruck aus dem...
With a Leaf from Dreiser's Original Manuscript
Dreiser, Theodore.
The Carnegie Works at Pittsburgh.
Chelsea, New York: Privately Printed, n.d. [1927]. No. 3 of 27 copies on Marlowe Antique. "Twenty-seven copies of this book have been printed privately in New York. Each copy contains a sheet of the original manuscript — Copy number one contains sheets one and twenty-eight of the manuscript" (from the..... Read More about The Carnegie Works at Pittsburgh
With 4 Original Drawings
Ferlinghetti, Lawrence.
In Search of Eros [aka Travels in America Deserta]. [Original Art and Production Archive].
[Louisville, Kentucky, and Pittsfield, Massachusetts: 1995]. Published: Louisville: White Fields Press, 1995. "Published in Heaven Chapbook" Series no. 56. With 4 Original Drawings. In Search of Eros is a chapbook celebrating poet and publisher and artist Lawrence Ferlinghetti, reproducing images of his graphic art and collecting essays by Ron Whitehead..... Read More about In Search of Eros [aka Travels in America Deserta]. [Original Art and Production Archive
Fraser, George MacDonald.
3 Typed Letters, signed ("George Fraser"), to Robert E. Skinner, on the Flashman novels, weapons, and accents.
The Bungalow, Baldrine, Isle of Man: 1983-1993. A choice clutch of correspondence from George MacDonald Fraser (1925–2008), author of the enormously popular adventures of Flashman, cad and scoundrel — or, "a coward, a bully, and a satyromaniacal philanderer" (ODNB) — who is nevertheless at the heart of the military and..... Read More about 3 Typed Letters, signed ("George Fraser"), to Robert E. Skinner, on the Flashman novels,...
NEW HAMPSHIRE with 11-line HOLOGRAPH POEM, with UNRECORDED TITLE
Frost, Robert.
New Hampshire. A Poem with Notes and Grace Notes.
New York: Henry Holt and Company, 1923. First edition, trade issue. NEW HAMPSHIRE with 11-line HOLOGRAPH POEM, with UNRECORDED TITLE. Inscribed and signed by Robert Frost, with an eleven-line poem in ink holograph on front flyleaf, with unrecorded title ("Winter Will Go") with eight variant textual differences from the final..... Read More about New Hampshire. A Poem with Notes and Grace Notes
Graham Greene's Own Copy
Greene, Graham.
The Power and the Glory.
New York: Viking Press, 1946. First American edition with this title, originally published in America in 1940 as The Labyrinthine Ways. Graham Greene's Own Copy. With a Typed Letter, signed, from Graham Greene, dated 10 March 199, stating that this is his own personal file copy and bears his ownership..... Read More about The Power and the Glory
Harris, Frank.
A Broadway Prostitute [Cover title].
Paris [i.e., New York?]: Privately printed for the Erotica Biblion Society, 1932. Contains two linked narratives, Abdallah Pasha's Seragilo [sic] and The Spanish Lady's Story, which are the opening episodes from A Night in a Moorish Harem by Lord George Herbert (ca. 1896). The attribution to the notorious Frank Harris..... Read More about A Broadway Prostitute [Cover title
LIMITED TO 50 COPIES, SIGNED BY SEAMUS HEANEY
(Heaney, Seamus) MacGill-Eain, Somhairle.
Hallaig … Translated by Seamus Heaney.
[Dunblane, Scotland]: Urras Shomhairle. The Sorley MacLean Trust, 2002. First edition, signed issue; limited to 50 numbered copies signed by Heaney from a total printing of 200 copies. LIMITED TO 50 COPIES, SIGNED BY SEAMUS HEANEY. An elusive title, especially in this signed issue. Read More about Hallaig … Translated by Seamus Heaney
1/25 SIGNED COPIES (with original photograph)
Heaney, Seamus.
Dove-Marks on Stone: Poems for George Mackay Brown. (Edited by K. A. Perryman).
(Schondorf, Germany/ Verona, Italy): Babel/ (Printed for Babel by Martino Mardersteig at Stamperia Valdonega), 1996. First edition, signed and illustrated issue; limited to 25 copies, signed by the contributing poets and the photographer, and illustrated with an original silver print portrait of George Mackay Brown by Gunnie Moberg [total edition..... Read More about Dove-Marks on Stone: Poems for George Mackay Brown. (Edited by K. A. Perryman
"HEDGE SCHOOL" (PRINTED BY THE JANUS PRESS)
Hedge School. Sonnets from Glanmore.
Newark, Vermont: Printed for Charles Seluzicki at the Janus Press, 1979. First edition, limited to 285 numbered copies (this #22), signed by Seamus Heaney and Claire Van Vliet. "HEDGE SCHOOL" (PRINTED BY THE JANUS PRESS). Book was designed, set, and printed by Claire Van Vliet at the Janus Press, Newark..... Read More about Hedge School. Sonnets from Glanmore
Himes, Chester.
If He Hollers Let Him Go.
Garden City, New York: Doubleday, Doran, 1945. First edition. Signed. Signed by the author on the front flyleaf. Himes' first novel, a sexually-charged exploration of the alienated consciousness of an African-American worker in an armaments plant in Los Angeles during World War Two, it earned him critical praise, favorable comparison..... Read More about If He Hollers Let Him Go
SCARCE TWO-VOLUME EDITION OF WASHINGTON SQUARE
James, Henry.
Washington Square. The Pension Beaurepas. A Bundle of Letters.
London: Macmillan and Co, 1881. First English edition, first impression. One of 500 copies. SCARCE TWO-VOLUME EDITION OF WASHINGTON SQUARE. An attractive copy of a scarce title, in the two-volume English edition, of which only 500 copies were issued in the first printing. Read More about Washington Square. The Pension Beaurepas. A Bundle of Letters
Joyce's First Publication
Joyce, James.
"Ibsen's New Drama" [in] The Fortnightly Review, April 1, 1900.
London: Chapman and Hall, Limited, 1900. Joyce's First Publication. Single issue. No. 400. New Series. April 1, 1900. Edited by W.L. Courtney. Octavo. pp. 527-718. Complete as issued with a 16-page "Fortnightly Review Advertiser" bound in at the front, and four-page color advertisement (The Royal Automatic "Bar-Lock" Visible-Writing Typewriter) tipped-in..... Read More about "Ibsen's New Drama" [in] The Fortnightly Review, April 1, 1900
Original Recording of James Joyce Reading 'Anna Livia Plurabelle' : Signed by Joyce
James Joyce Reading "Anna Livia Plurabelle" (Parts I & II).
Cambridge, (England): The Orthological Institute/ (Made in England by Gramophone Co. Ltd.), [circa 1929]. First pressing. Original Recording of James Joyce Reading 'Anna Livia Plurabelle' : Signed by Joyce. With inscribed slip by Joyce, to Jean [E. Mison], a freelance journalist based in Cambridge from approximately 1927 to 1964. Recorded..... Read More about James Joyce Reading "Anna Livia Plurabelle" (Parts I & II
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Tara Sullivan
Anthony Varvaro knew his life was about more than baseball, and that's exactly how he lived it
By Tara Sullivan Globe Staff,Updated September 16, 2022, 1:27 p.m.
Thousands attended the funeral procession of Anthony Varvaro at Our Lady of Good Counsel Church in Staten Island, N.Y.Jason Paderon/Staten Island Advance
NEW YORK — Row by row and shoulder to shoulder they stood, white-gloved hands raised in salute. The sea of blue barely moved, not as the midmorning sun shone down, not as the funeral procession drove by.
From the long column of police motorcycles that led the way to the final, flower-laden hearse that came to a stop in front of Our Lady of Good Counsel Church, hundreds upon hundreds of Port Authority police officers remained at attention.
How could they not?
Anthony Varvaro was one of their own. He'd honored their uniform in life; they were here to honor his uniform in death. This story, one so unspeakably tragic it's difficult to fathom, left more than one community shattered. The baseball community remembered Varvaro as one of its own, too, including the Red Sox, the last stop on his six-year major league career.
The 37-year-old father of four was killed by a wrong-way driver on the morning of Sept. 11, and was buried Thursday with the full honors of an officer killed in the line of duty. Varvaro died on his way to a 9/11 memorial event in New York City, a service for which he'd volunteered to work. As a man shaped by the events of 2001, when he and his then-high school classmates could see the smoldering city skyline from their classroom windows, Varvaro had long nurtured a dream of working in law enforcement. He fulfilled his wish in 2016.
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To do so, he had to turn in a different uniform, one that came with a cap and a jersey rather than a jacket and a badge, one that represented the other of Varvaro's childhood dreams: to make it to the big leagues. A 12th-round Mariners draft pick in 2005, Varvaro broke into the majors in 2010, spent the bulk of the next four seasons with Atlanta, and was traded to the Red Sox near the end of 2014.
But with season-ending arm surgery coming only after nine appearances, repeated injury and job uncertainty took their toll, and Varvaro walked away the following year, leaving a rehab assignment with the Pawtucket Sox when the Port Authority police called. If there's a fallback assumption that all major leaguers are somehow set for life, Varvaro disproved the notion, a mid-level draft pick who scratched and worked his way to the majors, received no huge signing bonuses or mega-million-dollar contracts. He just had a love of the game, a relentless work ethic, and a superior right arm.
His choice to leave it all behind resonated with his Red Sox colleagues of the day, not just for the courage of Varvaro's convictions, but for their unwavering faith he would wear both uniforms with honor and pride.
"I remember getting to know him during stretch in spring training of 2015," recalled pitcher Rick Porcello. "We had a common connection through people we knew at St. John's [University, where Varvaro pitched in college]. He had a great dry sense of humor that would make me laugh, but when it came time to work he was always focused and worked hard. I remembered him talking about leaving baseball to apply to the Port Authority and how much I admired the fact that he was putting his career aside to be home and to serve and protect."
There were some funny moments in the transition. In an interview on SNY a few years back, Varvaro recalled how a background-check call to the Red Sox front office, which occurred before Varvaro had a chance to alert anyone he'd gotten a call about the police exam he'd passed years before in Atlanta, prompted concern it might have been a hoax.
"I remember getting a call as part of the background-check process and checking with Anthony and telling him, 'I'm not going to talk to them unless you want me to,' " said Red Sox senior vice president Ben Crockett, the team's farm director in 2015.
Anthony Varvaro participated in spring training with the Red Sox in 2015.Barry Chin
As Varvaro recalled in the video, "I said, 'Listen, it's something I always had an interest in, and I'm letting it ride out and see where I stand at the end of the day,' and they said, 'OK.' I said, 'While I'm here, I'm a hundred percent all-in. But I want to see where it leads me.' "
That's how Crockett described him: "I said he was a standout citizen, a really hard worker. Anthony was really mature, soft-spoken, and driven. He cared about his teammates and the game, but he knew what he wanted when deciding to go to his family and pursue his real dream job."
Assurances were in place, but Varvaro's manager at the time, Kevin Boles, still thought there was major league life in his arm.
"I remember the day in 2016, we were in Buffalo I think, when he told me he was going to retire and move on and go into law enforcement," said Boles, now a minor league manager with the Syracuse Mets.
"And I said, 'Are you sure? You're doing really well, you have a chance for service again in the big leagues.' But he said, 'My dream is actually to be in law enforcement.' That put everything in perspective. Most guys, their dream is the big leagues.
"His is to serve."
That is the man the world lost last weekend, and sadder still, the father and husband a family lost. The unrelenting grief that enveloped the funeral Thursday spoke to the life Anthony Varvaro lived in 37 years, but also to the one he never gets to live. It spoke to the impact he had in serving his community, in teaching baseball to the next generation of Little League stars (he was recently elected president of his local organization), but also to the impact he could have continued to make, most especially to the four children he shared with his high school sweetheart and wife, Kerry.
There was one of his boys on Thursday, helping the uniformed pallbearers who'd shouldered his father's flag-draped casket back to the hearse, small arms extending out of one of his dad's old jerseys as they pushed the casket all the way into the car. Putting others first, a desire to help, Varvaro family traits.
One of Anthony Varvaro's three sons, wearing his little league jersey, helped pallbearers move Anthony's casket into the hearse on Thursday.Jason Paderon/Staten Island Advance
"I remember one appearance he had in '15 where we were getting blown out and he covered multiple innings and racked up a pretty high pitch count to save the rest of our bullpen," Porcello said. "I think that outing was a great example of what he is all about.
"He will be missed."
A charitable fund has been set up for the family, with a description that says everything about Varvaro and the reason he swapped those uniforms seven years ago.
"Nothing in the world mattered more to Anthony than his family, and this collection will ensure AJ, Johnny, Christian, and Savannah are taken care of for the future."
Tara Sullivan is a Globe columnist. She can be reached at tara.sullivan@globe.com. Follow her on Twitter @Globe_Tara.


The following image shows the MakerBot Replicator 2 printing specifications. These specifications are identical to the Replicator 2X except for build volume, which in 2X has decreased to 9.7 L x 6.0 W x 6.1 H due to a second print head being added.
Build volume is self-explanatory, but what's important to note are the maximum dimensions in each of the axes, as these will limit the part size and constrain orientation.


Shaped like a fuchsia fireball with swirling green-tipped flaps, the dragon fruit sells itself.
"People think, 'Wow, what is this thing and how can I not bring it home!'" said Jessie Capote, executive vice president of J&C Tropicals in Miami.
The delicately sweet tropical fruit, which has the texture of a kiwi and is studded with edible black seeds, is quickly going mainstream across the U.S.
Alex Berkley, sales manager at Frieda's Specialty Produce in Los Alamitos, Calif., said demand for the fruit has grown 40% in volume on average over the last three years, as the Florida crop grows stronger and more countries supply the U.S., including Israel, with its more tropical flavor, and Nicaragua, which provides "much juicer" fruit.
Mark Munger, vice president sales and marketing for Los Angeles-based 4Earth Farms, attributes dragon fruit's steady sales growth to consumers becoming more adventurous and curious to try new flavors, textures and food experiences.
Because the fruit is harvested ripe and ready to eat, it's easy for the consumer to choose one, said Marc Holbik, vice president of Ecoripe Tropicals Inc. in Miami.
The white dragon fruit, with bright pink skin and crisp white flesh, is the most popular and most abundant of the three varieties available to the U.S., and it adds excitement to fruit salads.
Holbik said the red variety, which has pink skin with smaller, more evenly placed scales and slightly sweeter magenta flesh, is growing in popularity for smoothies and acai bowls.
Not everyone prefers that variety, however.
"Some customers refuse to receive red-fleshed fruit because the purple juice stains their kitchens and bleeds into other fruit," said Peter Leifermann, vice president sales and marketing at Homestead, Fla.-based Brooks Tropicals.
There is also the bright yellow, white-fleshed dragon fruit, much of it grown in Ecuador's Amazon region. The pine-cone-shaped fruit, sweeter and fruiter than its red cousins, was allowed into the U.S. 18 months ago.
Though dragon fruit has been sold here for more than a decade, Leifermann said the market is still in its adolescent stage.
"Growers, shippers and importers are still fine-tuning best practices and figuring out how to get a return on their relatively large investment," said Leifermann, who handles Florida varieties.
The wildly exotic fruit can also be a challenge because it ripens in flushes every two to three weeks throughout the season, with each flush harvested over seven to 10 days.
When it comes to consumer education, the jury's out on the value of in-store sampling.
"Sampling in a demo or raw is a great way to get people to try it," said Robert Schueller, marketing manager for Melissa's World Produce, Los Angeles.
While Leifermann normally recommends sampling tropical fruit, he said the dragon fruit's powerful appearance makes it less reliant on sampling than one might think.
Schueller suggests displaying dragon fruit next to other tropicals that appeal to Asian and South American shoppers, such as mangoes, papaya, passion fruit, cactus pears and coconuts.
As for merchandising, Holbik said the exotic fruit does a great job on its own attracting attention in the produce department, especially when all three varieties are present.
"Cutting a fruit in half and displaying the impressive white or magenta flesh is a good way to increase sales," he said.


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Last edited by Dikinos
Saturday, May 16, 2020 | History
5 edition of She said it was all a lie found in the catalog.
by Tom Frisbie
Published October 29, 2007 by Outskirts Press .
Abuse - Domestic Partner Abuse,
Abuse - General,
Family & Relationships / Abuse / Spousal Abuse,
Self-Help : Abuse - General,
Family & Relationships,
Family/Marriage
Lillian Florence Hellman (J – J ) was an American dramatist and screenwriter known for her success as a playwright on Broadway, as well as her Communist sympathies and political activism. She was blacklisted after her appearance before the House Committee on Un-American Activities (HUAC) at the height of the anti-communist campaigns of –Occupation: Playwright, writer. She convinced one woman to pay her $14, for a rock she said came from a meteorite that she had obtained from a "NASA insider," according to press .
A new book published earlier this week called "She Said" by the New York Times reporter Jodi Kantor and Megan Twohey describes how the duo broke the story of former Hollywood producer Harvey. Aunt Polly—Tom's Aunt Polly, she is—and Mary, and the Widow Douglas is all told about in that book, which is mostly a true book, with some stretchers, as I said before. Now the way that the book winds up is this: Tom and me found the money that the robbers hid in the cave, and it made us rich.
Elvis Presley's notes show he probably read this book of the Bible most. She said she could tell it was "something special to him" by all the notes in the margins. was the book of Psalms Author: Caleb Parke. The Independent Books Puzzles indy very coercive," she said. "I was honestly scared of what he'd do if I gave him the real answer." and that can prompt people to lie, as one guy.
Australasian navies.
Niger Foreign Policy and Government Guide
School board amalgamation.
Treasures of prehistoric art.
Analog/hybrid solution of partial differential equations in the nuclear industry
Planning a Country Place (Country Home and Small Farm Guides)
Stay-away parents - how to draw them in
Belstone fox
Contractors and computers, why systems succeed or fail
Lunch Napkin, Veggie Tales
Drug Facts and Comparisons 2000 (2000 Drug Facts and Comparisons)
shifting sources of power and influence
United States Indian policy in Texas
Blast from the Past (Fairly OddParents)
Proactive Parenting
She said it was all a lie by Tom Frisbie Download PDF EPUB FB2
Out of 5 stars She said it was all a lie Reviewed in the United States on Febru As a victim/child advocate, I would recommend this book for any abuser or victim, so that they can see both sides, as the author has tried to portray.5/5(2).
The Paperback of the She Said It Was All a Lie by Tom Frisbie at Barnes & Noble. FREE Shipping on $35 or more!Author: Tom Frisbie. She said it was all a lie is the first in a series of recent pursuits, with work progressing quickly on the follow-up. Sign-up for the Outskirts Press newsletter and receive free publishing & marketing She said it was all a lie book.
item 3 She Said It Was All a Lie, Frisbie, Tom New Fast Free Shipping, 2 - She Said It Was All a Lie, Frisbie, Tom New Fast Free Shipping.
"She said it was all a lie" is a book I recently wrote. It can be found on In in, I take a woman from birth to where she is today and with help from many different people explain why she is what she is today. It explains what makes an abused person become then an abuser themselves.
It's a book about the fact that Cassie said yes in her life. That fact is what is important here, nothing else. I personally believe that if the murderers DIDN'T ask Cassie, it doesn't matter, she believed in Jesus Christ and had grown to love him as we all should/5. But I said once in some interview that every word she writes is a lie, including "and" and "the." Below are additional selected citations in chronological order.
The taped interview with Cavett aired in Januaryand when Hellman saw it she notified her lawyer and initiated a lawsuit for $ million against Mary McCarthy, Dick.
One girl wakes up in the hospital after a huge bomb has struck off. She has no memory of what happened to her and this gives the reader a sense of conflict in the story.
The doctor refers to her as J.D., which stands for Jane Doe. Apparently no one knows her, her parents are not in the picture, and she is all alone in the world.4/5.
Lie, on the other hand, is defined as, "to be, to stay or to assume rest in a horizontal position," so the subject is the one doing the lying—I lie down to sleep or When I pick up a copy of my favorite magazine, Writer's Digest, I lie down to take in all its great information—and not acting on an object.
In both these cases, you, the. 64 quotes from Wide Sargasso Sea: 'You can pretend for a long time, but one day it all falls away and you are alone. We are alone in the most beautiful p. 'Sometimes,' she said, 'they threaten you with something -- something you can't stand up to, can't even think about.
And then you say, "Don't do it to me, do it to somebody else, do it to So-and-so." And perhaps you might pretend, afterwards, that it was only a trick and that you just said it to make them stop and didn't really mean it.
"I said they called me back and they were really concerned about me and I said, 'Go on your honeymoon, don't worry about me, I'll be fine.' And that was all a lie." There was no phone call.
Pauline Kael (/ k eɪ l /; J – September 3, ) was an American film critic who wrote for The New Yorker magazine from to Kael was known for her "witty, biting, highly opinionated and sharply focused" reviews, her opinions often contrary to those of her contemporaries.
She was one of the most influential American film critics of her mater: University of California, Berkeley. Part Two Chapter 13 / To Kill a Mockingbird / "Put my bag in the front bedroom, Calpurnia," was the first thing / Aunt Alexandra said.
"Jean Louise, stop scratching your head," was. Read the excerpt from chapter 6 of Lizzie Bright and the Buckminster Boy. She glared at him. "Lizzie, I swear to you, as sure as I'm standing right here—that's a lie. Every bit of it. Every single bit." "My granddaddy said it was a lie, too." She leaned her head to one side and looked at him steadily.
"So why haven't you been down to the island?". The multi-million bestselling novel about a young girl's journey towards healing and the transforming power of love, from the award-winning author of The Invention of Wings and the forthcoming novel The Book of Longings Set in South Carolina inThe Secret Life of Bees tells the story of Lily Owens, whose life has been shaped around the blurred memory of the afternoon her mother was killed/5(K).
I said I would like it very much, which was a lie, but one must lie under certain circumstances and at all times when one can't do anything about them.
() Adulthood lesson numero uno: sometimes doing what people want you to do is the best way. Soldier's Home Lyrics Krebs went to the war from a Methodist college in Kansas. There is a picture which shows him among his fraternity brothers, all of them wearing exactly the same height and.
She has also said that profits from the book haven't been going to Alex. Another book about a boy who said he had gone to heaven, Heaven Is For Real, has been turned into a movie. "It will all make sense soon. Let's go home and rest. Tomorrow is a special day and I'm glad ya all chose to remain" Nashe said and they all nodded.
*** The next day Ray was on cloud 9. Everything had finally fallen into place. Precious brought some people from Nashe as promised.
And as she stood in front of her 5th grade class on the very first day of school, she told the children a lie.
Like most teachers, she looked at her students and said that she loved them all. And in many ways, "She Said" is more significant than "All the President's Men," and not just because journalism is currently under siege, financially and politically, in a way it was.
It was all a lie," she said in the ad. "Since then, over 50 million babies have been murdered. I will take this burden to my grave. Please, don't follow in my mistakes. DO NOT vote for Obama. Obama murders babies.". McCorvey issued a pro-life commercial in the election calling on pro-life voters to vote pro-life.
mpcs.online - She said it was all a lie book © 2020


The day of the court's judgment of Absalom arrives. The judge begins with the issue of the other two men in question, Absalom's cousin and the other accomplice. Despite the fact that Arthur's struck-down servant identified one of them, the judge maintains that this evidence is not conclusive, nor the evidence that the three of them met afterwards at Baby Mkize's house. He says that while these men clearly have criminal associations, there is no evidence that they participated in this crime, and so the charges against them are dismissed.
The judge appears to desire to follow the strictest letter of the law, and says that the state has not conclusively proved that the other men were with Absalom at all. And so, his adherence to the law causes guilty men to walk free. The Judge allows the law to guide him to not listen to the only truth-teller—Absalom—and to be manipulated by those who lie.
The judge continues on the issue of Absalom. He admits that Absalom has confessed to, in a very straightforward manner, the crime that he committed, and shows deep remorse. He talks about how Mr. Carmichael is trying to make an argument for a simple boy mislead by Johannesburg. But the judge argues, society has created laws, and if those laws are broken, then society must fix itself and fix the laws—but until then, such laws are just. In other words, judges cannot do anything but enforce the law, even if it's is broken in a way that reflects society's brokenness.
The judge hand-waves towards the fact that perhaps there is something wrong with their society, but acknowledges that it is his job to enforce the existing laws, not change them.
But, he continues, the issue at the heart of the case is whether or not Absalom intended to kill. Though he insists that he did not, the evidence of him bringing a loaded revolver to the crime scene suggests otherwise. While he may not have intended to murder, he brought along a means to hurt someone very badly. Thus, he must be found guilty of murder. On the issue of mercy, the judge claims that he finds no extenuating circumstances, and thus cannot recommend mercy. He sentences Absalom to death. Absalom falls to the ground, weeping. Msimangu and the young white man from the reformatory lead a weak Stephen from the courtroom, breaking the custom of whites and blacks leaving separately.
It is tragic, then, that the same adherence to the law, with no considerations for age or social forces or honesty, remorse, or confession, leads to the guilty conviction and death sentence for Absalom. The custom of racial separation in the courtroom is broken when a white man and black man must help Stephen stand—only the depths of this tragedy can disrupt the cycle of harmful, artificial separation of the races.
Machado, Carmen. "Cry, the Beloved Country Book II, Chapter 28." LitCharts. LitCharts LLC, 5 Aug 2013. Web. 18 Jan 2019.
Machado, Carmen. "Cry, the Beloved Country Book II, Chapter 28." LitCharts LLC, August 5, 2013. Retrieved January 18, 2019. https://www.litcharts.com/lit/cry-the-beloved-country/book-ii-chapter-28.


Shri. Sanjiv Saraf is Non Independent Non-Executive Chairman of the Board of Polyplex Corporation Ltd. He is promoter Director of the Company and is associated with the Company since its inception. Shri Sanjiv Saraf is B.Tech from Indian Institute of Technology (NT), Kharagpur. Shri Saraf has guided the Company from the time of the setting up of Company's first Polyester Film project in 1988 to the subsequent expansions and diversifications in India as well as through its subsidiaries abroad. He was the Managing Director of the Company for over sixteen years.
Shri. Pranay Kothari is Chief Executive Officer, Non-Independent Whole Time Director of Polyplex Corporation Ltd. He is a qualified Chartered Accountant and Company Secretary and has been associated with the Company since 1985. During his tenure with the Company he has held the positions of Company Secretary, Director (Operations) (Whole Time Director). He was last appointed as Whole Time Director designated as Executive Director for a term of three years w.e.f. September 7, 2006. Shri Pranay Kothari is a professional director of the Company.
Shri. Sanjiv Chadha is Non Independent Non-Executive Director of Polyplex Corporation Ltd. He is a Non Resident Indian and practicing as an Architect in the United States of America. Shri Sanjiv Chadha is B. Arch from Indian Institute of Technology (IIT) and has done M.S. Architecture from Illinois Institute of Technology, U.S.A. He is member of American Institute of Architecture, Association of Licensed Architect, International Council of Shopping Centers and International Facilities Management Association.
Shri. Jitender Balakrishnan is Independent Non-Executive Director of Polyplex Corporation Ltd., since July 20, 2010. He has done his BE (Mech) from National Institute of Technology (NIT), Madras University and has PG diploma in Industrial Management from Bombay University. He has served on the Board of IDBI Bank Limited as Executive Director and thereafter as Deputy Managing Director and Group Head – Corporate Banking. He has served on the Board of Directors of various Corporates in the areas of Oil and Gas, Refineries, Infrastructure Projects, Cement, Fertilizers, Hotels, Pharmaceuticals, Paper etc.
Shri. Ranjit Singh has been appointed as Additional Non-Executive Independent Director of the Company. He has resigned as Chief Operating Officer, Non Independent Whole Time Director of Polyplex Corporation Ltd. He joined Polyplex in 1996. Mr. Singh has been instrumental in enhancement in productivity and quality levels at plant, besides institutionalizing cost cutting measures and a process driven approach in the Company. He is a qualified Mechanical Engineer and an MBA from the Indian Institute of Management, Ahmedabad.


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First high-GLA safflower oil on market
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The first high-GLA safflower oil has reached the market at commercial scale after six years of research and development work by Arcadia Biosciences, Inc. (Davis, California, USA).
With 44% minimum GLA, SONOVA™ 400 delivers 400 milligrams (mg) of γ-linolenic acid (GLA) per gram (g) of oil. Other sources of GLA deliver considerably less, including borage oil (20%), evening primrose oil (10%), black currant oil (15–20%), and hempseed oil (up to 5%).
"We have significant commercial volumes currently available," said Frank Flider, Arcadia's vice president of business develop-ment. "In a short time, we will be able to supply a very substantial portion of the world's current GLA demand. Additionally, we are ramping up to supply new demand that is expected to develop with the availability of this more concentrated and cost-effective source of GLA."
The market for GLA has suffered in past years from "very inelastic availability," Flider noted, adding that sudden increases in de-mand caused wild price swings and made it difficult for formulators of finished products to secure adequate supplies at stable prices.
"As a result," he said, "new product development and research have suffered and very few new products featuring GLA have been introduced over the past several years."
Metabolic Pathway and Applications
GLA is an omega-6 fatty acid (18:3n-6), synthesized in the body by the action of the ∆-6 desaturase (D6D) enzyme on linoleic acid (LA; 18:2n-6). Because the activity of D6D diminishes as a result of aging, stress, pollution, diet, smoking, drinking, and other activities of daily living, our bodies may produce suboptimal levels of GLA.
Once synthesized or ingested, GLA quickly is elongated to dihomo-γ-linolenic acid (DGLA; 20:3n-6). DGLA is a precursor to two important anti-inflammatory metabolites: prostaglandin PGE1 and 15-OH-DGLA. Many of the favorable effects of GLA are attributed to increased tissue levels of PGE1, which is known to suppress chronic inflammation. The anti-inflammatory benefits of GLA are recognized in medical foods such as Abbott Nutrition's Oxepa®, which is used to modulate inflammation in sepsis, ARDS (acute respiratory distress syndrome), and ALI (acute lung injury). Although the body of literature concerning the effects of dietary GLA is sparse compared with the burgeoning body of research on omega-3 fatty acids, there is some indication that GLA combined with omega-3 fatty acids may exhibit synergistic effects.
Animal and human studies suggest that dietary GLA may provide relief from rheumatoid arthritis and other inflammatory disorders. GLA has also been found to be helpful in alleviating the effects of atopic eczema, hyperactivity disorders, cyclical mastalgia (premenstrual breast pain), diabetic neuropathy (pain and loss of peripheral nerve function), and high blood pressure.
Dietary GLA has been shown to reduce low-density lipoprotein cholesterol, plasma triacylglycerols, and smooth muscle prolifera-tion. It may also be helpful in treating dry eye conditions. In vitro studies have characterized GLA's selective cytotoxic effects on more than 30 types of cancer cells. Others have shown evidence of the suppression of breast cancer genes, tumor growth, and metastasis. A study by Marie A. Schirmer and Stephen D. Phinney of the University of California, Davis, USA, showed that GLA helped maintain weight loss for people who had lost weight (Journal of Nutrition 137:1430–1435, 2007).
Recent studies on evening primrose oil have shown that dietary GLA has a measurable effect on skin softness, moisturization, and wrinkle reduction. This has not gone unnoticed by the personal care and cosmeceutical industries and may represent a significant new market for GLA.
In fact, there is a long, documented history of medicinal use of GLA-containing plants such as evening primrose. The Algonquin Indians chewed the seeds and rubbed the seed oil onto flesh wounds, according to Herbal Medicine in Endocrinology and Metabolic Disease (Food Products Press, Binghamton, New York, USA, 2005). The oil was known in Europe as the "King's Cure All"because of its beneficial properties.
Although GLA does not have a DRI (Dietary Reference Intake), estimations of the amount that constitutes a therapeutic dose range from 500 to 2,000 mg daily. Given that standard 500-mg capsules of evening primrose oil contain only 50 mg of GLA, the attractions of an oil that contains 44% GLA become immediately apparent.
Development of High-GLA Safflower
The high-GLA safflower plant was developed through a combination of plant breeding and biotechnology.
As Flider previously noted (inform 16:279–282, 2005), Calgene LLC developed transgenic canola oil varieties containing as much as 43% GLA. (Calgene was a biotech research and development company in Davis, California, USA, that Monsanto Co. acquired in 1996.)
"This was accomplished by introducing ∆-6 and ∆-12 desaturase genes from the fungus Mortierella alpina into canola cells,"Flider writes. ". . . Despite the fact that Calgene conducted several generations of field trials on high-GLA canola varieties, for reasons not made public, the product was never commercially produced."
Why safflower for the next attempt? Most safflower already is produced in defined growing regions throughout North America by contract farmers, making identity preservation easier to achieve. Because safflower is self-pollinating, pollen drift is minimal and identity preservation is improved relative to canola.
A further disadvantage of canola as a platform is the presence of significant quantities of α-linolenic acid (ALA; 18:3n-3). Production of stearidonic acid (18:4n-3) at the expense of GLA is possible in canola because ALA competes with LA for ∆-6 desaturase activity.
Cost and Market
SONOVA 400 is being marketed and distributed by Bioriginal Food & Science Corp., Saskatoon, Saskatchewan, Canada, in partnership with Arcadia.
In support of its commercialization program, Arcadia successfully completed the US Food and Drug Administration (FDA) regulatory process for GLA safflower in December 2009. Following established procedures for New Dietary Ingredients in Dietary Supplements, the FDA reviewed and acknowledged extensive data supporting the safety of GLA safflower, allowing it to be marketed and sold as an ingredient in dietary supplements.
"We have petitioned Canada but have not yet started on other geographies," said Flider. "We are exploring regulatory requirements for Europe and Japan as well as other Asian and South American countries, but at this point have taken no formal action. We hope to be able to offer SONOVA 400 worldwide within a few years.
"Typically, the cost involved with doubling the concentration of an active component will result in a per-unit price very signifi-cantly higher than two times," Flider said. "Because it isn't necessary to fractionate or concentrate the GLA through physico-chemical means, the per-unit GLA price for SONOVA 400 will be reasonably competitive with borage oil GLA.
"SONOVA 400 is the first in what we hope to be a line of nutritional and functional oils developed by Arcadia," he continued. "As we have lines of GLA safflower producing oil in excess of 65% GLA, more concentrated versions of SONOVA GLA oils can be expected in the foreseeable future."
Catherine Watkins is associate editor of inform and can be reached at cwatkins@aocs.org.
AOCS
2710 S. Boulder, Urbana, IL 61802-6996
© 2019 The American Oil Chemists' Society


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text:
Q: frequent crashs using ubuntu 17.10 I have recently installed ubuntu 17.10 on DELL optiplex 3020 and I increase the amount of RAM from 8GB to 16GB. But I got frequently crashs in many applications such as: chromium, firefox , visual Studio. Sometimes all the session freezed and I have to reboot the pc.
I run the command memtester 16G 1 and I got this result:
Loop 1/1:

Stuck Address       : ok
  Random Value        : ok
  Compare XOR         : ok
  Compare SUB         : ok
  Compare MUL         : ok
  Compare DIV         : ok
  Compare OR          : ok
  Compare AND         : ok
  Sequential Increment: ok
  Solid Bits          : ok
  Block Sequential    : ok
  Checkerboard        : ok
  Bit Spread          : ok
  Bit Flip            : ok
  Walking Ones        : ok
  Walking Zeroes      : ok
  8-bit Writes        : ok
  16-bit Writes       : ok

the output of echo $?:
0

I'm able today to boot the sytem after the 4 fourth test and I got a black screen when I tried to reboot the pc contains many information such as kernel panic not sync.
Does this problem is due to the hardware or the image of ubuntu that I installed?
Below is the syslog's file:
syslog


text:
Unsure You Have Depression? Examining Depression Symptoms
Depression is not a hidden illness. People facing these disorders exhibit evident symptoms which according to doctors are signs of clinical depression. On the other hand it can be said that it is quite easy to overlook these symptoms and as a result be unable to help one self.
It is not necessary for a person to possess all the symptoms to be said to be in depression. In addition the time of attack also varies with the symptoms. Hence if a person shows considerable symptoms, they should be diagnosed.
Some of the basic symptoms of depression are:
Extended sessions of sadness or not having a "drive". A feeling of wanting to be out of everything rather than being in it. Feeling bad about oneself is the best symptom.
Feeling disgusting, pessimistic; another common symptom is having no target, nothing to look forward to. This feeling combined with perennial pessimism is a strong symptom and gives rise to hopelessness.
A consistent feeling of guilt makes a person feel as if he doesn't deserve to be happy. This feeling of loss of self worth is a tell-tale symptom of depression. Having a feeling that one will never get what he wants, in other words having no hopes whatsoever is also a strong symptom.
In addition to having no pleasure, the loss of interest of finding pleasure; dropping things that once gave enjoyment. These symptoms show just how depressed someone can be. It is like being in a mess and having no feeling of getting out of it. It leaves a person with nowhere to go.
Consistent fatigue, always being tired: the loss of interest in the minds of people suffering from depression has drastic effects on their physical energy. They don't feel like doing anything, they don't eat or sleep adequately.
There is so much of the negative stuff going in one's mind that he finds trouble trying to concentrate. He gradually becomes inefficient in terms of his memory and also being indecisive are trademark symptoms that a person is in depression. His lack of interest in everything makes him backward and not up to date, as a result he tends to lose track of things that happened or people said. Sometimes it also leads to the person being inattentive. There is a category of symptoms which if visible call for an appointment with a doctor: inadequate or excessive sleep, regular breaking of sleep at wee hours, losing appetite or excessive eating shows ones lack of energy.
Thinking about committing suicide, talking about death, about ones intention to die are clear symptoms of depression. In addition one becomes restless and irritable as a result of poor mental health. Small disorders such as headaches, digestive disorders, various body pains, etc. are also the result of depression. All in all we can say that an unwell mind has its effects on all body parts and causes problem in most activities that a human undertakes ranging from eating to sleeping.
Feeling Down, Dumpy, Depressed? Don't Let an Under...
How To Cope With Loss And Trauma For A Person With...
Antidepressant Drugs Are Used To Treat Depression ...
How to Deal With Panic Attack Depression
Depressive Dog - Here Are The Reasons Why
Combat Depression With These Tips
Share the Fun and Humor With Funny Life Quotes
Coping With Depression - Antidepressants, Serotoni...
ADHD and Bipolar Disorder - Five Differences Betwe...
How Long Does it Take For BHRT to Start Working?
Depression Symptoms
Alternative Depression Medication - 3 Ways to Star...
Optimistic Thinking and How to Get It
Buddha and Walking the Path Alone
19 Facts About Depression At Midlife - Tips, Strat...
Uncontrolled Anger Can Lead to Arguments and in th...
Unsure You Have Depression? Examining Depression S...
You're Depressed Because You Are Ugly? It's Not Yo...
Depression and Alternative Treatments
Bipolar Disorder and Manic Depression Explained
Unsure Whether You Are Suffering From Clinical Dep...
Psychotic Depression
Some Ways to Improve Depression Without Medication
American Dreams of Cheese Lead to Traps: Of Mice a...
Diagnosing Clinical Depression - The Official Guide
Automatic Car Wash Case Study - Phoenix Depressed ...
Anxiety Muscle Fatigue - One of the Major Symptoms...
Understanding Ways to Control Endometriosis and Co...
Eating Chocolate To Help Prevent Depression?
Depression - Reasons, Symptoms - What Can You Do?
Depression and Nutritional Deficiencies
Marcus Aurelius and Acceptance
How to Beat the Black Dog of Depression and Have B...
Medical Problems and Sleeping Too Much
Can Gluten Intolerance Cause Depression?
How to Deal With an Extended Job Search
Tips On Dating Someone With Bipolar Disorder
Netherlands' Research Indicates 5HTP Benefits Anxi...
Stroke Depression - How to Beat Depression After S...
Overcoming Depression and Anxiety - The Root


text:
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redpajama_set_name: RedPajamaGithub


text:
Q: Cassandra paging on timestamp ordered data: filtering by clustering key vs native pagination I have such table:
CREATE TABLE events_by_user (
   user_id text,
   date timestamp,
   event_id text,
   event_data text,
   PRIMARY KEY ((user_id), date, event_id)
)
WITH CLUSTERING ORDER BY (date DESC, event_id ASC);

and I want to do pagination on it.
So, query pattern could be like: select first 10 events, select next 10 events and so on.
I see two options here:

*

*native manual paging https://datastax.github.io/java-driver/manual/paging/

*use limit + filter on clustering key:
SELECT * FROM events_by_user WHERE user_id = :id AND date < :since LIMIT 10
How cassandra will handle it on large number of data in partition?
Second approach seems more flexible, because data can be filtered by random dates.

A: Second Approach is is more efficient and flexible to use.
With the First Approach you can't jump to any state but with 2nd one you can.
And there is a limitation with First One from DataStax doc

The paging state can only be reused between perfectly identical statements (same query string, same bound parameters). Altering the contents of the paging state or trying to set it on a different statement will cause this method to fail.

And I have inserted 10 Million events with your schema into a single userid.
Here is the performance
|------------------------------------|
| Driver Paging | Cluster Key Paging |
| --------------|--------------------|
|  1345026 ms   |      1210296 ms    |
|------------------------------------|

A: With regards to your query SELECT * FROM events_by_user WHERE user_id = :id AND date < :since LIMIT 10 it may cause you to miss some rows - as the event_id is also used in the clustering key.
A simple example would be a user_id= that only has a single date= and 100 rows with different event_id (all using the same date=). In this case the query will return the 10 first rows and the next query will miss the rest not return anything.
Pagination is done by the driver in a very similar way to the queries you are trying to execute, by passing additional data paging_state. Please note:

*

*Pagination does not require to return back page size results - it may return less and may take into account performance related optimization when returning results.

*The code of option 2 will continue reading the next page as long as the number of returned rows is equal to the limits. Pagination will need one less query in the cases in which a partitions rows divide by the limits request  (e.g. #rows % limits = 0). In these cases the last iteration in option 2 will need to try and fetch the "next page" and get back 0 rows,  while the driver may use an extra bit returned with the data marking that there is no additional data.
https://git-wip-us.apache.org/repos/asf?p=cassandra.git;a=blob_plain;f=doc/native_protocol_v3.spec

*Result paging
The protocol allows for paging the result of queries. For that, the
  QUERY and   EXECUTE messages have a  value that
  indicate the desired   page size in CQL3 rows.
If a positive value is provided for , the result
  set of the   RESULT message returned for the query will contain at
  most the    first rows of the query result. If that
  first page of result   contains the full result set for the query, the
  RESULT message (of kind Rows)   will have the Has_more_pages flag
  not set. However, if some results are not   part of the first response, the Has_more_pages flag will be set and the result   will
  contain a  value. In that case, the  value
  should be used in a QUERY or EXECUTE message (that has the same
  query than   the original one or the behavior is undefined) to
  retrieve the next page of   results.
Only CQL3 queries that return a result set (RESULT message with a
  Rows kind)   support paging. For other type of queries, the
   value is   ignored.
Note to client implementors:

*

*While  can be as low as 1, it will likely be detrimental
  to performance to pick a value too low. A value below 100 is probably too
  low for most use cases.

*Clients should not rely on the actual size of the result set returned to
  decide if there is more result to fetch or not. Instead, they should always
  check the Has_more_pages flag (unless they did not enabled paging for the query
  obviously). Clients should also not assert that no result will have more than
   results. While the current implementation always respect
  the exact value of , we reserve ourselves the right to return
  slightly smaller or bigger pages in the future for performance reasons.

*The  is specific to a protocol version and drivers should not
  send a  returned by a node using the protocol v3 to query a node
  using the protocol v4 for instance.