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5 minutes reading time (1016 words)
Dabrafenib Plus Trametinib Approved For Unresectable or Metastatic BRAF V600E Mutations
Anaplastic thyroid carcinoma micrograph.
The FDA has given accelerated approval to dabrafenib (Tafinlar®, Novartis) in combination with trametinib (Mekinist®, Novartis) for treatment of adult or pediatric patients with unresectable or metastatic solid tumors with a BRAF V600E mutation and no satisfactory alternative treatment options. This approval is based on three clinical trials: the Rare Oncology Agnostic Research (ROAR) phase 2 basket study, the NCI-MATCH Subprotocol H study, and Study X2101 which was specific to the enrollment of pediatric patients with refractory or recurrent tumors; with support from results in the studies COMBI-d, COMBI-v, and BRF113928.
"BRAFV600 mutations are and early and common driver mutation in these well-differentiated thyroid tumors, with additional late-event mutations that promote progressive dedifferentiation to anaplastic thyroid cancers", wrote Vivek Subbiah, MD, Associate professor in the Department of Investigational Cancer Therapeutics at MD Anderson Cancer Center, and colleagues, in their publication of the ROAR trial (NCT02034110), on which this approval was partially based. "The dual inhibition of the MAPK signaling pathway improves treatment response and delays or prevents MAPK pathway reactivation, a known resistance mechanism. This strategy has been successful in treating BRAFV600-mutant melanoma and lung cancer, whereby combined BRAF plus MEK inhibition increased overall response frequency, duration of response, progression-free survival and overall survival compared with BRAF inhibitor monotherapy."
The safety and efficacy of dabrafenib plus trametinib were assessed in of 131 adult patients from the ROAR phase 2, open-label, nonrandomized study and the NCI-MATCH Subprotocol H phase 2, open-label, single-arm study, as well as 36 pediatric patients, ages six to 18, from parts C and D of the Study X2101 phase 1/2a, multi-center, open-label study. Each study evaluated the end point of overall response rate.
Within the three studies, a total of 24 tumor types were represented, including low-grade gliomas (LGG) and high-grade gliomas (HGG), biliary tract cancers, adenocarcinomas of the small intestine, gastrointestinal stromal tumors, anaplastic thyroid cancers, and other solid tumors. In the group of the 131 adult patients evaluated, 54 patients (41%) had an objective response. Among the tumor types with the highest representation, there was an overall response rate of 46% for biliary tract cancer, 50% for LGGs of any subtype, and 33% for HGGs of any subtypes. In the group of the 36 pediatric patients with LGGs or HGGs evaluated, the overall response rate was 25%, with a secondary end point duration of response recorded to be 78% at the six-month mark and 44% at the 24-month mark.
The most common adverse reactions in ≥20% of adult patients were pyrexia, fatigue, nausea, rash, chills, headache, hemorrhage, cough, vomiting, constipation, diarrhea, myalgia, arthralgia, and edema.
The most common adverse reactions in ≥20% of pediatric patients were pyrexia, rash, vomiting, fatigue, dry skin, cough, diarrhea, dermatitis acneiform, headache, abdominal pain, nausea, hemorrhage, constipation, and paronychia.
"This study showed that dabrafenib plus trametinib showed meaningful response rates and durable clinical benefit in patients with recurrent gliomas with BRAFV600E mutations, regardless of glioma subtype." concluded Patrick Wen, MD, Professor of Neurology at Dana-Farber/Harvard Cancer Center, and colleagues, in their publication of the ROAR study (NCT02034110), on which the approval was partially based. "Molecular screening strategies that include BRAFV600E mutations will be crucial for identifying patients who might benefit from this treatment combination, and we recommend that testing is adopted in clinical practice for patients with glioma."
The recommended dosage for adult patients is 150mg of dabrafenib, orally twice daily plus 2 mg of trametinib orally once daily. The recommended dosage for pediatric patients being treated with dabrafenib and trametinib is based on body weight. It is noted that a recommended dose has not been established in patients who weigh less than 26 kg. Additionally, dabrafenib plus trametinib is not indicated to be used in patients with colorectal cancer because of resistance to BRAF inhibition, as well dabrafenib is not indicated to be used in patients with wild-type BRAF solid tumors.
Wen PY, Stein A, van den Bent M, et al (2022). Dabrafenib plus trametinib in patients with BRAFV600E-mutant low-grade and high-grade glioma (ROAR): a multicentre, open-label, single-arm, phase 2, basket trial. Lancet Oncol, 23(1):53-64. DOI:10.1016/S1470-2045(21)00578-7
Salama, A, Li S, Macrae E, et al (2020). Dabrafenib and trametinib in patients with tumors with BRAFV600E mutations: results of the NCI-MATCH trial subprotocol H. J Clin Oncol, 38(33):3895-3904. DOI:10.1200/JCO.20.00762
Subbiah V, Kreitman RJ, Wainberg ZA, et al (2018). Dabrafenib and trametinib treatment in patients with local advanced or metastatic BRAF V600-mutatnt anaplastic thyroid cancer. J Clin Oncol, 36(1):7-13. DOI:10.1200/JCO.2017.73.6785
US Food and Drug Administration (2022). FDA grants accelerated approval to dabrafenib in combination with trametinib for unresectable or metastatic solid tumors with BRAF V600E mutation. Available at: https://www.fda.gov/drugs/resources-information-approved-drugs/fda-grants-accelerated-approval-dabrafenib-combination-trametinib-unresectable-or-metastatic-solid?utm_medium=email&utm_source=govdelivery
Novartis (2022). Novartis dabrafenib plus trametinib receives FDA approval for first tumor-agnostic indication for BRAF V600E solid tumors. Available at: https://www.novartis.com/news/media-releases/novartis-tafinlar-mekinist-receives-fda-approval-first-tumor-agnostic-indication-braf-v600e-solid-tumors
Tafinlar® (dabrafenib) prescribing information (2022). Novartis. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/202806s022lbl.pdf
Mekinist® (trametinib) prescribing information (2022). Novartis. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/204114s024lbl.pdf
Clinicaltrials.gov (2021). A study comparing trametinib and dabrafenib combination therapy to dabrafenib monotherapy in subjects with BRAF-mutant melanoma. NLM identifier: NCT01584648.
Clinicaltrials.gov (2021). Dabrafenib plus trametinib vs vemurafenib alone in unresectable or metastatic BRAF V600E/K cutaneous melanoma (COMBI-v). NLM identifier: NCT01597908.
Clinicaltrials.gov (2021). Study to investigate safety, pharmacokinetic (PK), pharmacodynamic (PD) and clinical activity of trametinib in subjects with cancer or plexiform neurofibromas and trametinib in combination with dabrafenib in subjects with cancers harboring V600 mutations. NLM identifier: NCT02124772.
Clinicaltrials.gov (2022). Efficacy and safety of the combination therapy of dabrafenib and trametinib in subjects with BRAF V600E-mutated rare cancers. NLM identifier: NCT02034110.
Clinicaltrials.gov (2022). Study of selective BRAF kinase inhibitor dabrafenib monotherapy twice daily and in combination with dabrafenib twice daily and trametinib once daily in combination therapy in subjects with BRAF V600E mutation positive metastatic (stage IV) non-small cell lung cancer. NLM identifier: NCT 01336634.
Clinicaltrials.gov (2022). Testing trametinib and dabrafenib as a potential targeted treatment in cancers with BRAF genetic changes (MATCH-Subprotocol H). NLM identifier: NCT04439292.
Image Credit: Nephron. Licensed under CC BY-SA 3.0
FDA approval dabrafenib trametinib BRAF V600E metastatic cancer
Lyn Brook is an Editorial Assistant at i3 Health and is a regular contributor to Oncology Data Advisor. Twitter: @Lyn_i3Health
Friday, January 27, 2023 Pembrolizumab Approved for Adjuvant Treatment of Non–Small Cell Lung Cancer
Thursday, January 26, 2023 Discussing the Relevance of Urine Studies in Myeloma With Kelsey Natsuhara, MD
Wednesday, January 25, 2023 Overcoming Knowledge Gaps in Thyroid Cancer Management
Tuesday, January 24, 2023 GLAONS Survey of Oncology Nurses Reveals Knowledge Gap Regarding Novel Treatment Options
Monday, January 23, 2023 Zanubrutinib Approved for Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma
Friday, January 20, 2023 Tucatinib Plus Trastuzumab Approved for Colorectal Cancer
Pembrolizumab Approved for Adjuvant Treatment of Non–Small Cell Lung Cancer
Tucatinib Plus Trastuzumab Approved for Colorectal Cancer
Mosunetuzumab-axgb Approved for Relapsed/Refractory Follicular Lymphoma
Pafolacianine Approved for Detection of Lung Cancer Lesions
Nadofaragene Firadenovec-vncg Approved for Non–Muscle-Invasive Bladder Cancer


Conveyancing-Principles & Practice provides a succinct understanding of the historical and philosophical background of land law and conveyancing in Kenya, a thorough grasp of the legal framework and a simplified concise exposition of the processes and formalities that precede the legal transfer of land. It combines a technical understanding of complex legal phenomenon with some critical awareness of the broader values and preferences which inform the law. The book is alive to the fact that land law and conveyancing impinge upon a vast area of social ordering and expectations, and exert a fundamental influence upon the lifestyles of ordinary people. Most importantly, Conveyancing-Principles and Practice is designed along the new Advocates Training Programme as a core text for students of conveyancing, conveyancers, legal practitioners, real estate investors, estate agents, commercial and banking institutions, auctioneers, Government departments and the citizenry. Dr. Tom O. Ojienda is an advocate and a senior lecturer at the School of Law, Moi University. He holds a Bachelor of Laws (LL.B) degree from the University of Nairobi, a Master of Laws (LL.M) degree from Kings College, London and a Doctorate in Law (LL.D) degree from the University of South Africa, Pretoria. He has served as a consultant for the Commission of Inquiry into the Land Law Systems in Kenya (Njonjo Commission), World Bank Land Law Reform Project (2002) and was part of a team that did preliminary research for the Commission of Inquiry into Illegal/Irregular Allocation of Public Lands (Ndungu Commission). Dr. Ojienda has been part of the legal and technical team that formulated National Land Policy Formulation Process and has been instrumental in land reform in Kenya. His publications include Conveyancing- Theory and Practice (2002); A General Introduction to the new Law of the Sea (2002); Consolidating Kenya�s Democratic Gains (2003); and Anti-Corruption and Good Governance in East Africa (2007). He is a Commissioner with the Kenya�s Truth Commission, and has served as the President of The East Africa Law Society, the Vice-President of the Pan African Lawyers Union and Chairman of the Law Society of Kenya. He sits in the National Environment Tribunal (Net), the council of the International Bar Association (IBA), the Council of Legal Education (CLE). Dr. Ojienda also serves as a member of the Board of the Kenya Industrial Property Institute (KIPI) and the Board of the American Biographical Institute (ABI).


Located in Sulphur Springs, Texas, IDS is a short drive from the Dallas / Ft Worth metroplex. IDS was founded in 1997 by Bill Wilder. Bill holds a computer science and business degree from Texas A & M University in Commerce. Prior to establishing IDS, Bill worked for a verity of software developers. He has over 30 years experience in software engineering, design, development, and implementation.
IDS focuses on making disparate pieces of software work with each other. Predominantly working with local authorities and regional businesses, IDS has carved out a successful niche making different systems within businesses and local government communicate, making life easier and more productive for the end users.
Dan Wilder has over 30 years of B2B sales, marketing and operational success. He has a productive track record in the design and field implementation of successful sales strategies, marketing promotions and training applications, drawing on well-developed analytical and creative problem solving and negotiation skills. Dan received his BBA from The University of Texas at Arlington.
IDS draws from a team of professionals located all over Texas. Each provides specialist expertise ranging from hardware, to security, as well as business process engineering. IDS is not just another software vendor. IDS looks at the business/government need and provides the linking pieces between legacy systems and newer applications.


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Tagged: Chris Hemsworth
Review: "Bad Times at the El Royale" One of The Best Films Of The Year
"Bad Times at the El Royale" is the latest film from Drew Goddard. Much like his 2012 horror gem "The Cabin in the Woods," this homage to the murder mystery films of the 1960s...
Movie Preview: Thor: Ragnarok
Production: Marvel Studios/ Walt Disney Pictures Starring: Chris Hemsworth, Tom Hiddleston, Cate Blanchett, Karl Urban, Idris Elba, Jeff Goldblum and Mark Ruffalo Directed by: Taika Waititi (Based on the Marvel Comic by Stan Lee,...

redpajama_set_name: RedPajamaCommonCrawl


The perfect travel buddy for those looking to take their passion for photography to the next level.
Instant gratification is the name of the game with MeFoto's new HyperLock leg lock System. MeFoto's mission is simple: make setting up your tripod or monopod faster than ever while making it lighter, smaller and more stable.
Less is more is MeFoto's philosophy. Less weight, less stress, more stability, more fun!
While MeFoto is setting a new standard for speed and compactness, they want to ensure industry compatability where it counts.


Nurses should make sure they always proprely document their work. When a nurse writes a clear and precise description of what happens to a patient when he is under her care it not only helps her and the staff make sure the patient is proprely being taken care but it also protects the nurse in case of a potential lawsuit. A nurse who defends herself by saying "I did it but I forgot to document it" will have trouble convincing the jury in a medical malpractice trial.
Not only nurses should document everything but they should make sure their notes are easy to read. Even though a nurse may have been doing the right thing, unreadable notes open the door for a patient to question the nurse's actions in considering filing a medical malpractice lawsuit.


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Q: Connecting to Teradata with R through DBI and ODBC I connect to Teradata using the Teradata SQL Assistant. The connection parameters consist of a server address and a driver (server info changed for privacy reasons), as shown below:
Name: my_teradata_connection
Teradata Server Info: 00.11.22.333
Data Source: Teradata Database ODBC Driver 16.20
UID: My_User_ID
PWD: My_PWD

I am trying to use R to connect to Teradata, using the DBI and odbc packages.
con <- DBI::dbConnect(odbc::odbc(),
                      Driver = "[your driver's name]",
                      Host   = "[your server's path]",
                      DBCName = "[IP Address or Alias]"
                      UID    = rstudioapi::askForPassword("Database user"),
                      PWD    = rstudioapi::askForPassword("Database password"))

It seems obvious the Driver should be Teradata Database ODBC Driver 16.20. But where do I put the Teradata Server Info that we'll say is  00.11.22.333? Should it populate the Host or the DBCName arguments? And whichever one it does not populate, what will go there?

A: Usually, in most DB-APIs including ODBC connections server and host are synonymous keywords where you will not see both together but only one (of course with exceptions). Specifically, per odbc documentation, dbConnect maintains the optional server argument:
dbConnect(
     drv,
     dsn = NULL,
     ...,
     timezone = "UTC",
     timezone_out = "UTC",
     encoding = "",
     bigint = c("integer64", "integer", "numeric", "character"),
     timeout = 10,
     driver = NULL,
     server = NULL,
     database = NULL,
     uid = NULL,
     pwd = NULL,
     dbms.name = NULL,
     .connection_string = NULL
)

However, the ... indicates additional ODBC driver keywords that would be specific to corresponding driver, here being Terdata ODBC driver.

...          Additional ODBC keywords, these will be joined with the other arguments to
  form the final connection string

And from ODBC Driver for Teradata 16.20 documentation, Driver and DBCName are required keywords.DBCName appears to be synonymous to server or host given the IP address or alias indication.

DBCName = <IP-addr-or-alias>

| Keyword/Synonym                                             | Description                                                                             |
|-------------------------------------------------------------|-----------------------------------------------------------------------------------------|
| Driver=<driver-path>                                        | [Required] The full path to the ODBC Driver for Teradata shared objects…                |
| Description=<data-source-desc>                              | [Optional] Descriptive text about the data source.                                      |
| DBCName=<IP-addr-or-alias>                                  | [Required] The IP address or FQDN (fully qualified domain name) of the Teradata server… |
| Username=<name> or UID=<name>                               | [Optional] The default username for logging onto a Teradata server system.              |
| Password=<password>                                         | [Optional] The password required for the default Username.                              |
| DefaultDatabase=<database-name> Or Database=<database-name> | [Optional] The default database associated with the specified data source…              |
| UPTMode                                                     | Default = NOTSET…                                                                       |

Therefore in R, use the DBCName only. Below adds in the optional Database keyword.
# KEYWORD APPROACH
con <- DBI::dbConnect(odbc::odbc(),
                      Driver   = "Teradata Database ODBC Driver 16.20",
                      DBCName  = "00.11.22.333",
                      Database = "myDatabase",
                      UID      = rstudioapi::askForPassword("Database user"),
                      PWD      = rstudioapi::askForPassword("Database password"))

# CONNECTION STRING APPROACH
con_str = "Driver={Teradata Database ODBC Driver 16.20};DBCName=00.11.22.333;Database=myDatabase;"

con <- DBI::dbConnect(odbc::odbc(),
                      .connection_string = con_str,
                      UID = rstudioapi::askForPassword("Database user"),
                      PWD = rstudioapi::askForPassword("Database password")

redpajama_set_name: RedPajamaStackExchange


text:
Australian government to share intelligence with Iranian regime
Peter Symonds
The visit by Australia's foreign minister Julie Bishop to Iran last weekend, the first in more than a decade, again highlights the role of Australia as a diplomatic point man for the United States in international affairs.
Having marched in lockstep with Washington in its diplomatic confrontation, crippling sanctions and war threats against Tehran over the past decade, Bishop's mission was to feel out the possibilities for greater collaboration with Iran in securing US economic and strategic interests in the Middle East and beyond.
Bishop's trip took place as Iran's foreign minister Mohammad Javad Zarif published an op-ed comment in Monday's New York Times effectively offering Iran's services as a junior partner to US imperialism in the Middle East—the role that it played prior to the 1979 revolution that overthrew the dictatorial rule of Shah Reza Pahlavi. The comment comes in the wake of an international framework agreement to end the decade-long standoff over Iran's nuclear programs.
Bishop's main achievement was to secure an unprecedented "informal" intelligence-sharing arrangement with Iran that would include information gathered in Iraq in the war against Islamic State of Iraq and Syria (ISIS). The US and its allies are already in a de facto alliance with Iran in propping up the Shiite-dominated government in Baghdad against the Sunni extremist militias that seized large parts of the north and west of the country last year.
Justifying the intelligence arrangement with Tehran, Bishop declared the ISIS was the "most significant global threat at present" and had changed the geostrategic and political landscape in the Middle East in a way that no one envisaged. "And now the conversation we are having about how to cooperate to defeat this common enemy is not a conversation I thought we would be having," she said.
The abrupt about-face by the Australian government simply echoes moves in the same direction by Washington. Having branded Iran as part of an "axis of evil" in 2002, the US is now seeking to finalise a nuclear deal as a step towards a possible wider rapprochement. Far from being a step towards peace, the US moves are in preparation for wider wars not only in the Middle East but Russia and China.
While providing few details of the intelligence-sharing arrangement, Bishop was optimistic that it would have major benefits, including to track down Australian citizens fighting with ISIS. "They [Iranians] are very present in Iraq. The Revolutionary Guard is on the ground, they are working with security forces. They are carrying out operations in Tikrit and elsewhere, they are all over the place," she enthused.
These remarks highlight the utter cynicism with which the US and allies such as Australia exploit "human rights" issues. Just a year ago, Washington and Canberra were denouncing Iran, and the Iranian Revolutionary Guard Corp in particular, for propping up the Syrian "dictator," President Bashar al Assad, while ISIS was part of the US-backed "democratic revolution" to overthrow Assad.
The new attitude was summed up by Peter Jennings, head of the government-backed Australian Strategic Policy Institute, who is well connected in military and intelligence circles. He explained in the Australian that it would be absurd to refuse to take intelligence from Iran just because it commits human rights violations.
"The only sensible response is to say we will do it and start a process of cooperation, and we will know in good time if anything useful for us or for them comes out of it," Jennings declared. He also made clear that "highly classified Australian [intelligence] product" was not going "to be shoved over to the Iranians."
The Australian government's contempt for democratic rights was underscored by Bishop's efforts to secure a deal to return Iranian refugees in Australia to Iran where they will face possible persecution and jail.
Former intelligence analyst and "independent" parliamentarian Andrew Wilkie was more strident in his criticism. He branded the Iranian regime as the "most ruthless and untrustworthy in the world" and declared that Australia was "dancing with the devil" by concluding an agreement with a country that used torture to extract information.
Wilkie's comments reflect the continued opposition of sections of the US Congress, as well as Israel and other US allies in the Middle East, to any deal with Iran over its nuclear programs and other issues. That is likely why the Obama administration was content to allow Australia to proceed and absorb any public criticism.
Sunday, January 17, 2pm AEDT
A tribute to Barry Jobson—Australian Trotskyist
The Socialist Equality Party will hold an online public meeting to commemorate the life of Barry Jobson, a longstanding comrade.
The response in Washington to Bishop's announcement has been notably low-key. US State Department spokeswoman Marie Harf simply repeated that the US was not coordinating with Iran on the ISIS threat and was "trying to get a little more information" on the intelligence-sharing arrangement.
The Australian's defence editor Brendan Nicholson noted yesterday that Bishop would keep "the Americans fully apprised of what is happening." He pointed out: "It is likely that the Americans will look favourably on additional sources of information which they, like Australia, can weigh and accept or reject."
In reality, the US intelligence apparatus undoubtedly knew about the intelligence sharing deal well in advance and gave it the green light. The proposal was first mooted last year and discussed in October when Bishop met Iranian foreign minister Zarif. American spy agencies will gain access to any Iranian intelligence data handed to their Australian counterparts through the so-called Five Eyes sky network.
While she has been touting the benefits of the new arrangement for Australian intelligence, Bishop has been silent on what Tehran is expecting in return. When asked if Australian citizens fighting with ISIS could be placed at risk, she said she would not comment on "a matter of deep intelligence operational issues." In reality, the Australian government has already given the green light to the US military to assassinate its citizens through drone strikes.
Bishop did refer to the deranged hostage-taker in the Sydney siege, Iranian refugee Man Haron Monis—a hint that information could be exchanged on the activities of other Iranian refugees in Australia. Such actions could have severe consequences for Iranian political exiles and their families from a regime that is notorious for brutally suppressing its opponents especially leftists and socialists.
With the proviso that an international nuclear agreement is finalised, Bishop made clear that her visit was just the first step in opening up closer economic and political relations with Iran. Australia would "very much value further dialogue," she told Iranian President Hassan Rouhani.
AustraliaIranMiddle EastUnited StatesAsia and the Pacific


THIS IS A QUALITY, AFFORDABLE AND COMFORTABLE REPLACEMENT WRAP BACK SUSPENSION SEAT WITH A UNIVERSAL MOUNTING BRACKET (SEE DIAGRAM). THIS YELLOW SEAT WILL FIT MOST JOHN DEERE FARM UTILITY TRACTOR MODELS. THIS SEAT HAS A DURABLE MOLDED STEEL FRAME AND A COMFORTABLE SELF DRAINING TWO PIECE CUSHION DESIGN FOR OPERATOR COMFORT.
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THIS SUSPENSION SEAT HAS AN ADJUSTABLE OPERATOR WORKING RANGE FROM 100 265 LBS. Please check out the photos, diagrams and seat mounting information provided in this listing. Compare this information closely to your current seat application for compatibility. It is the buyers responsibility they are purchasing an item that will fit their application. Our goal is to have the BEST SELECTION of seats and accessories, offer you the BEST SEAT choice for your application, and give you the BEST DEAL possible!
The item "YELLOW WRAP BACK TRACTOR SUSPENSION SEAT JOHN DEERE 1020, 1530, 2020, 2030 #WE" is in sale since Sunday, February 10, 2019. This item is in the category "Business & Industrial\Heavy Equipment, Parts & Attachments\Heavy Equipment Parts & Accessories\Tractor Parts". The seller is "seatwarehouse" and is located in Indianapolis, Indiana.


Aimee has been with Events By Ashley since the start 2 years ago. She is eager to help and is genuinely engaged in the needs of our clients and their guests. Aimee is the problem solver of our team and is always willing to take on challenging heights to acheive gorgeous event decorations!


Augmented Reality (AR) blurs the boundary between the physical and digital worlds. In AR's current exploration phase, innovators are beginning to create compelling and contextually rich applications that enhance a user's everyday experiences. In this book, Dr. Helen Papagiannis - a world-leading expert in the field - introduces you to AR: how it's evolving, where the opportunities are, and where it's headed.
If you're a designer, developer, entrepreneur, student, educator, business leader, artist, or simply curious about AR's possibilities, this insightful guide explains how you can become involved with an exciting, fast-moving technology.
Computer vision, machine learning, cameras, sensors, and wearables change the way you see the world; Haptic technology syncs what you see with how something feels; Augmented sound and hearables alter the way you listen to your environment; Digital smell and taste augment the way you share and receive information; New approaches to storytelling immerse and engage users more deeply; Users can augment their bodies with electronic textiles, embedded technology, and brain-controlled interfaces; Human avatars can learn our behaviors and act on our behalf.


Specs of all Samsung Galaxy A9 2018 models and all Samsung Galaxy A9 2018 variants. All the differences of each model, specifications and features. The Samsung Galaxy A9 2018 versions may be different for each country.
The Samsung Galaxy A9 2018 has 4 models and variants. Generally the variants are the same device models with some different features and specifications, as the amount of internal storage, processor or just 3G/4G frequencies that may be different depending on the country where the Samsung Galaxy A9 2018 is sold.
Compare the 4 Samsung Galaxy A9 2018 models and know what are the specifications that differ one from another version in the full datasheet. Learn about all Samsung Galaxy A9 2018 versions.
Countries or regions where this model is sold: Brazil, Europe, India, Malaysia.


Bananas are fibre rich fruits with a number of health benefits. But do bananas and weight loss go hand in hand?
Bananas are the fourth most popular food after rice, wheat and corn.With its high nutrient content, low price and easy availability it is the most ideal fruit to include in your daily diet and is also good for weight loss.
If you eat almost nothing and just bananas, you lose weight, but if you eat eight to ten bananas a day, apart from consuming regular meals, you can gain weight.
Nutritionist Yulia Tarbath tried the banana diet for 12 days to detoxify her body and lose weight naturally.
Also read: Security Guard Left With Bananas In Hand While Thieves Run Away With Rs 90 Lakh!
· You eat all the bananas you desire and bananas are all you eat (you can also do it with other fruit). It is a mono island, however, occasionally; people also add 1 type of greens, such as lettuce in the last meal of the day.
· You eat ONLY ripe bananas, you eat your usual calories – no under-eating or calorie-restricting is involved.
· You drink plenty of water, up to 3 litres a day.
· You exercise as normal.
· You rest enough as your body will be going through deeper detox and restoration.
· Research shows that bananas can actually be a perfect fit in your weight loss diet plan. A six inch banana has about 90 calories, which makes it much lesser than the calories in any candy bar. Moreover, the fibre content in this fruit is soluble, which causes it to absorb water and slows down digestion.
· Did not have any detox symptoms whatsoever, felt amazing throughout the whole "journey".
· Experienced very sharp clarity of mind, which allowed her to restructure tasks and activities.
· She says it was a busy inner journey for her.
· She felt balanced and positive.


text:
DKE
Join the Department of Data Science and Knowledge Engineering
Our department - part of the Faculty of Science and Engineering of Maastricht University, the Netherlands - is growing rapidly. We are excited to welcome new colleagues to strengthen our research and education in Artificial Intelligence, Data Science, Computer Science and Applied Mathematics.
You can find the list of positions for your consideration below, as well as a brief introduction to the city of Maastricht, our department and what we have to offer. If you have any questions about these positions or about us, please do not hesitate to reach out using the contact details at the bottom of this page. We will gladly get to know you.
Tenured and tenure-track positions
Optional joint industry appointments
Benefits including pension scheme, partially paid parental leave, optional collective healthcare insurance
Diverse and international work environment
Excellent opportunities for collaboration
Full professor in Intelligent Interaction
Full professor in Explainable Artificial Intelligence
Associate professor in Data Fusion and Integration (tenure track, optional joint industry appointment)
Assistant Professor in Machine Learning (tenure track, optional joint industry appointment)
Assistant Professor in Optimization (tenure track, optional joint industry appointment)
Two lecturers (with a background in Computer Science, Mathematics or Engineering)
Postdoctoral researcher (1,0 fte) in Cybersecurity - application deadline passed
PhD student in Artificial Intelligence and Human Activity Recognition - application deadline passed
Assistant/associate professor in Cybersecurity
Assistant professor in Cognitive AI
Assistant professor in Extended/Augmented Reality
Assistant professor in High Performance Computing
Assistant professor in Signal & Image Processing
Assistant professor in Statistics
Working and living in Maastricht
The Sint Janskerk, Basilica of Saint Servatius and Basilica of Our Lady
The city of Maastricht developed from a Roman settlement into a flourishing European city.
Maastricht is best-known for the 1992 Treaty of Maastricht, which laid the foundation for establishing the European Union. Given the city's location, this is hardly a surprise: Maastricht lies in the heart of Europe, within 30 kilometers from the Belgian and German borders. The city and its inhabitants have a strong international character which is reflected in our department.
However, there is more to the city than just its cross-border character. For example, Maastricht has the second highest number of monuments in all of the Netherlands: roughly 1 monument for every 73 inhabitants, second only to the Dutch capital of Amsterdam. This historical decor forms the backdrop for year-round cultural events, such as festivals, international art fairs, concerts and more. Just outside of the city, you can stroll through rolling hills and explore cave complexes.
Maastricht is a safe and family-friendly city, where - in true Dutch fashion - getting around by bike is common and easy. Compared to other Dutch college cities, housing is affordable and accessible. If you are unfamiliar with the Netherlands, the university's Knowledge Centre for International Staff will gladly assist you with practical matters.
Discover Maastricht
Knowledge Centre for International Staff
More about working at Maastricht University
UM is the tenth best young university in the world
Times Higher Education 2019 Young Universities Ranking
DKE: The Department of Data Science and Knowledge Engineering
The department celebrated the 25th anniversary of its bachelor's programme in 2017.
We have nearly 30 years' experience in research and teaching.
Our efforts focus on four complimentary fields: Artificial Intelligence, Data Science, Computer Science and Applied Mathematics. The department's contributions to areas such as multi-agent systems, (medical) signal and image processing, game theory and AI search techniques are internationally recognized. DKE maintains a large and worldwide network of public and private collaborators, and our staff is firmly rooted in multiple national and international research networks.
Next to our research, we take pride in our education. Our master's programmes are nationally ranked #1 in the AI and Computer Science categories, and we offer our students an award-winning honours programme in collaboration with companies in the Euregion.
DKE is a community consisting of ~50 researchers at various stages of their career, nearly 600 BSc and MSc students and a team of 13 dedicated support staff members. Together, we come from over 40 different countries. DKE is strongly committed to maintaining the safe and supportive atmosphere at our department. We provide an unbiased and welcoming environment. DKE believes that diversity in the broadest sense - including diversity of gender, age, and nationality - makes us all better.
In-house expertise
Education at DKE
Artificial Intelligence is the #1 'Artificial intelligence' master's programme in the Netherlands
Keuzegids Masters 2019
Data Science and Knowledge Engineering is the #2 'Artificial Intelligence' bachelor's programme in the Netherlands
Keuzegids Universiteiten 2020
Data Science for Decision Making is the #1 computer science master's programme in the Netherlands
Collaborations and embedding
Our research and teaching is characterized by a collaborative and cross-disciplinary character.
We engage in projects and applications which require us to push boundaries in the fields of Artificial Intelligence, Data Science, Computer Science and Applied Mathematics. Of course, we are eager to provide new colleagues with access to our worldwide network of collaborators.
The department is active in networks such as ICAI (The Innovation Center for Artificial Intelligence), CLAIRE (The Confederation of Laboratories for Artificial Intelligence in Europe) and IPN (ICT Platform Netherlands). We maintain over 30 industry partnerships through our KE@Work programme, which places talented students with regional businesses under academic mentorship. Our KE@Work partners include companies such as Ericsson, Q-Park and Statistics Netherlands. Staff partakes in large-scale research consortia, for example through European Horizon 2020 projects, and collaborates with research partners such as the Moffitt Cancer Center in Florida (US) and Nikhef, the Dutch National Institute for Subatomic Particle Physics.
Within the university
Maastricht University itself offers no shortage of inspiring collaborators. We collaborate with researchers from all of the universities' six faculties.
Furthermore, DKE is embedded in the university-wide Data Science network, DS@UM.
The Faculty of Science and Engineering
It's exciting times for STEM research in Maastricht.
Within Maastricht University, DKE is part of the Faculty of Science and Engineering (FSE). A number of exciting developments are taking place in the faculty, which houses several outstanding departments and institutions covering education and research in Science, Technology, Engineering and Mathematics (STEM) as well as the liberal arts and sciences.
Notably, construction of the next-generation gravitational wave detector prototype – the ETpathfinder – is about to commence in Maastricht. This brings global STEM challenges to our doorstep and sets the stage for cutting-edge research, including at the interface of physics and Data Science/AI.
From ETpathfinder to Einstein Telescope?
Construction of ETpathfinder may only be the beginning: Maastricht is one of two candidate locations left for constructing the Einstein Telescope itself, an underground gravitational wave detector consisting of three arms of 10 kilometers long. The second potential location is the island of Sardinia in Italy. A decision is expected in 2021 or 2022.
We will gladly answer any questions you have. Feel free to get in touch with us:
Ellen Narinx-Schrauwen
Manager, Department of Data Science and Knowledge Engineering
ellen.narinx<at>maastrichtuniversity.nl
Gerhard Weiss
Professor of Computer Science and Artificial Intelligence
Head of the Department of Data Science and Knowledge Engineering
gerhard.weiss<at>maastrichtuniversity.nl
KE@Work/MaRBLe 2.0


text:
havefaith@faith-pr.co.uk
Award Writing
Insights and PR Audits
How we ended up working in PR
Written by Faith PR
Figuring out which career path you go down in life can be really difficult. You may find yourself trying all sorts of different things before you truly discover your niche and working in an industry or job your truly feel is the right fit for you.
Our team have shared their stories on how they have all followed different paths through their careers, to all come together working in PR.
Stefanie, founder and MD
I did a degree in modern languages, so initially pursued a career that combined marketing with my language skills. My first job was working for McCann Erickson on their Bentley Motors account on the prospecting of customers around the globe.
I then moved to a full-service agency, JDA (where I met Carl, my husband, who used to own the agency!), as an account manager and after six months was seconded to the PR department. I remember feeling that I had found my 'thing' and loved it so much I begged Carl to let me move to that team permanently at the Christmas party. Maybe not the wisest move but it paid off and I spent three more years in the PR department, eventually heading it up temporarily, until leaving to start Faith PR.
Emily, account director
I always say I ended up working in PR by default. I'd set out for a career in languages, studying Spanish and Italian, and by chance ended up temping for a PR agency when I left university as PR admin assistant – and the rest is history as they say! As a career it's perfect for me, as I love writing, creating and telling stories and working with people.
Matthew, digital PR account manager
I stumbled into PR while trying to figure out what I wanted to study at university. I was torn between journalism and a business-related degree, as they were both areas I was interested in. After some digging, I came across the PR course at Leeds Beckett University. It seemed like a great mix of what I was looking for and an interesting industry to enter into! As they say, the rest is history, I joined the course and never looked back!
The course at Leeds Beckett was focused on gaining industry experience, so throughout my time at university I was able to develop and grow my PR skills. The experience was invaluable when it came to looking for a PR role when I graduated.
Kirsty, social media and digital account manager
How I ended up in the industry was on a bit of a whim really. I didn't quite know what to study after leaving college, or I even wanted to go straight back into education after the summer break. When it was time to firm up my plans, I turned to an online quiz to help me decide (of all things to base your future on!) what kind of career I'd be suited for, and PR/marketing happened to be in the top three. The first was photography but it was a hobby I didn't want to turn into a career, and I think the third was journalism.
As I wasn't 100% sold on going to university, I took a gap year to as a break from education and instead changed jobs to work full-time elsewhere. That helped me conclude I needed some direction in a future career that an undergraduate degree would be able to provide.
Kate, PR account manager
I ended up working in PR almost by accident really. I took voluntary redundancy from the Reporter Group after 20 years in the job. I'd had enough of office closures and a total lack of investment in our titles so decided to take the plunge and do something totally different – teaching French and Spanish to primary school children.
But as soon as I left, former colleague Melanie Hill asked me if I could also do some copywriting for her PR company and it turned out I was much better at writing features and press releases than teaching other people's children the Spanish words for farmyard animals. A full-time job in PR came up, I took it and the rest, as they say, is history!
Abi, account executive
I went to Leeds Beckett University and studied journalism and, while in my third year, I undertook a work placement with Faith PR. This was what opened my eyes to working in the PR industry, and when Stef got in touch and offered me my first role in the industry I was thrilled!
Nicole, office manager
I was offered an apprenticeship by Faith PR. I worked as an apprentice for a year and was then offered a full-time job as an administrative assistant. The industry moves really quickly and we're constantly on with something new, each day is different. I have since become the office manager and it's been 5 and a half years since my first day!
Looking to work in the PR industry?
For anyone still searching for their perfect career then don't worry, it takes time. Plus your next big career move could just be round the corner…
Let's be honest as well, you need to be happy and satisfied with the career path you choose since you spend one third of your life working! So why not delve deep into really figuring out what will make you happy.
© Faith PR 2021
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text:
Uncategorized September 23, 2018
Inspiring Stories from Stafford
We've prepared this FAQ about VoyageHouston in an effort to ensure that anyone who is interested can have a full understanding of what we do and why we're doing it.
Who started Voyage
Hi everyone – I'm Mayank and I'm one of the two founders of Voyage. I was born in Miami, Florida and lived in South Florida through high school. My parents came to this country with very little, but they scraped some savings together, borrowed on their credit card and bought a small business and ran it together for almost 30 years. We weren't wealthy, but my parents never wanted their lack of wealth to interfere with my ability to grow, learn, and pursue the dreams that I had. After high school I moved to LA to attend UCLA, which is where I met my cofounder Sid. After college, I was fortunate to land an incredible job as an investment banker at one of the world's top banks. My parents were proud, their decades of sacrifice had helped their son "make it." I worked in LA and NY for a few years, but then I left banking because I wanted to make an impact on the world in a different way. I wanted to figure out how to help people who were like my parents, but just starting out. Sid and I started building a tool to help small businesses build their own websites, but there were already so many of those, so we stopped working on that and focused on what we felt no one was doing – telling the stories of everyday heroes. We wanted to build a platform fully focused on telling as many stories and bringing as much exposure as we could to hard-working people who were doing something entrepreneurial, creative or artistic with their lives.
Hi everyone, My name is Sid and I'm one of the co-founders of Voyage. I came to the US for college and ended up falling in love with everything about America, in particular the free-thinking and anything-is-possible spirit. I went to UCLA to study neuroscience and become a doctor, but realized that medicine was not my passion. Through some struggle trying different jobs, I ultimately found software engineering to be extremely fun and fulfilling. So many people helped me along the way and encouraged me to find my passion. What I realized through my journey is that many other people struggle to find what they are passionate about too, and once they find it they end up having a positive impact on the world. These people have great stories but because they aren't necessarily famous, the story is often untold. A few years ago Mayank and I partnered to provide web-development services to freelancers, artists, and small businesses – a group of creators close to our hearts. By talking to these people we learned about their amazing struggles and successes, but realized no one was sharing their stories. So, we set out to be the ones to uncover and share the human stories behind the people pursuing their passions, who we often see and drive past, and maybe even interact with everyday, but know little about.
Our mission & ethos
We believe that our communities are great because of the little guys and gals, the mom-and-pops, rising artists, local makers, creatives, and others who go off the beaten path, take risks and try to serve their community with something unique and special.
Our goal is for people to spend more of their money with mom and pops, local artists, creatives and makers rather than with large, one-shape-fits-all corporations.
We think if people knew more about the lives, journeys, struggles, values and background stories of the local business owners, artists, etc they would be more engaged with them, more likely to do business with them and support them in other ways. We believe the best way to do that is to help get the stories of local hidden gems out there, because once people get to know each other at a deeper level we are confident our communities will become even closer and more supportive.
Over time we plan to grow and deepen our involvement with the community beyond storytelling, to include in-person events that promote local artists and entrepreneurs, etc. We are excited and touched by the number of people that have expressed an interest in being part of that growth.
How we differ from traditional magazines
We are a platform that highlights the extraordinary life stories of everyday folks, told in their own words.
We do not have a masthead: For us, this started as a passion project. We are a small team that works with freelancers and contributors because there is an enormous number of amazing, untold stories that deserve to be told. Our contributors are not reporters – they are real people who work with us because they believe in our mission. By working remotely, part-time etc., they are able to support the magazine based on their availability. Through their efforts, we are able to learn from, and share the stories of many more people than we otherwise could. As such, our outreach contributors are free to use nicknames, first names or pen-names in their communications to preserve their privacy and avoid being contacted personally (i.e., on social media by people looking to connect). Since our outreach contributors may come and go, we do not require them to have a staff bio on our website. Our stories don't have by lines because we allow interviewees to tell their stories in their own words, eliminating the (well-intentioned) interference of a writer's voice.
We are not journalists: We do not provide headline news. We don't analyze politics or preach policy. We are in the business of finding amazing people and giving them a platform to tell their own stories in their own words.
Inclusive rather than exclusive: We strive to be an inclusive platform, rather than an exclusive club. Many media outlets create value through exclusivity, featuring a very small number of people each year.
We believe in the opposite approach. We believe in supporting people who are up-and-coming, as well as established. We believe in sharing the struggles behind the success, not just the accomplishments. And we believe in getting to know the person and their philosophy, not just their art, product, or business. We believe that by telling more stories we can make a bigger impact on our communities and the world. If only a handful of stories are told, then only a handful of people can benefit from the power of storytelling. We think communities are better when we know each other at a deeper level, but that's not possible if we are only exposed to the stories of a select group and tiny percentage within the community.
We value diversity: We take pride in the diversity you'll find on our site. You'll find people of all different backgrounds, races, countries of origin, religions, sexual preferences, gender identifications, professions, education levels, colors, shapes, and sizes featured on our site. Relative to almost any other media organization, on a typical day, even a cursory glance at our homepage will highlight how much more diverse we are relative to almost any other media outlet. This is intentional. We strive to make our platform accessible to groups that have traditionally been underrepresented in the media.
Authenticity over polish: We publish people's stories in their own words, even when there are grammatical issues because we believe it's important to highlight that not all successful people sound the same, have flawless writing skills, etc. If every time you see a feature of someone successful in the media and everything about them is perfect – from editing their responses to photoshopping their images to remove every "imperfection," you may get the false idea that successful people are perfect and that if one is not perfect, they might not be capable of success. We want to debunk this myth by showing that success comes in many forms/styles/education-levels/writing-styles, etc. That said, we all make mistakes, so if you notice an error in your submission after the fact, we are more than happy to work with you to correct it.
What happens with the information and pictures you submit to us
If you participate in a Q&A interview (our primary feature format), your answers and pictures will only be used for the interview and promotion of the interview. It will not be used for ANY other purpose. We do not sell your data, and we also do not use the information you provide to analyze it for marketing purposes.
We use Google Analytics to keep track of our website traffic. However, we DO NOT aggregate, share, sell or otherwise use data for any other commercial purpose other than keeping track of our traffic.
We may reach out to you in the future via email or social media to see if you are interested in collaborating with us again on another series, event, project etc. If you ever want us to stop reaching out you can let us know easily by clicking the "preferences" button in any of our emails to you.
Where are we based
We are based in Los Angeles, California, where we started our first site VoyageLA.com. Our mailing address is: 9415 Culver Blvd, STE 207 Culver City, CA 90232. This is the co-working space from where we first started, though we now work out of multiple co-working places and many of our contributors and outreach team are remote. Given our access to phones, e-mail, Skype, and other digital forms of communication, our contributors have the flexibility and freedom to work from wherever is convenient to them.
Why we ask for recommendations
The power in most media organizations is concentrated among a tiny group of people in the editorial department who decide who will get coverage and who won't. Often, these editorial elites can be removed from the heart of the community. By valuing recommendations we are able to take power out of the editorial office and distribute it to the people – so that the community is helping to drive coverage decisions rather than a small group of editorial elites. This allows us to feature thought-provoking art that may not be the most commercially successful (yet), and/or highlight the stories of trailblazing women that are making a difference in all fields.
What we are most excited by
On our platform, we have been blessed and amazed to see what people we featured a few months or years ago have accomplished since because we were able to connect with them when they were still an up-and-coming artist or entrepreneur. We want our site to be a positive and inspirational place, but know the path is not always easy. We have been particularly touched by the stories of people who we happened to connect with at a time of personal or professional difficulty in their life, like when they were making a career change to leave a 9-5 and pursue a passion. We love getting updates about how them sharing their story helped their business, self-confidence, re-connected them with old clients/followers who never knew their personal story, or allowed them to chronicle and journal their journey.
We can't wait to read and share your story!
Related ItemsMust Read
bill cox
i saw the link to you magazine through facebook about phil morgan (dju entertainment), he is a great talent, dj, singer and comedian "conroe chad".
i work with steve and daisey wells 832-437-2478 and they are about to get a reality show "on the road…". they are a great story.
congrats on your magazine and thanks for focusing on local Houston talent.
Evon Boykins
This is AWESOME!GOD BLESS YOU, all, for making a difference in people's lives. We matter! Our stories matters.
Linda Alvarado
I just love this! From your amazing stories come other amazing stories! Just as it is the little quirks and idiosyncrasies that make a person lovable and unique, such it is for a city as well. Thank you for highlighting the hidden inspirations that really make Houston what it is!
Sylvia Sierra
Love your feature stories. Please add me to your mailing list!
Charlie L
Love the site. As a 20-year Houston resident (moved from DFW) I have to say I'm a huge fan of Houston and I'm REALLY glad to have found this site to be explore more of Houston and continue bragging on the city to my friends.
Erika Lavan
Blessings to you Sid and Myank ❤
Everyone has a story and most of those stories are pretty inspiring in some way. THANK YOU guys for doing something that I have always wanted to do but just never really know how.
Craftsemble
Great job guys!! I pray you are rewarded for your stewardship. Looking out for others is such a honorable deed.
Wow! God bless you both! I would love to be added to your mailing list:)
More in Uncategorized
The heart of our mission at VoyageHouston is to find the amazing souls that breathe life into our city. In the...
Local StoriesJune 14, 2017


text:
Forsyth Central High School
Football: Creekview beats Central to secure top seed in Region 7
Grizzlie force Bulldogs into seven consecutive punts
Forsyth County News
CANTON — If this was Creekview head coach Al Morrell's last home game, there's no doubt he went out in style.
Senior quarterback Hayden Hall accounted for 326 total yards of offense as the Grizzlies honored Morrell, who announced he will end his 31-year career following the 2012 season, by securing the top seed in Region 7A-AAAAA with a 47-14 win over the Forsyth Central Bulldogs on Friday at The Den.
"Great deal of relief and a lot of satisfaction," Morrell said. "I'm very proud of the coaching staff and the kids and just the great effort. It ws a good night for Creekview."
The Grizzlies (7-1, 4-0 Region 7A-AAAAA) and Bulldogs (2-6, 2-2) traded touchdowns on their opening drives of the game, but Creekview's defense never looked back as it managed to hold Forstyh Central to seven consecutive punts while the offense piled on the points.
"That's a good football team," Forsyth Central coach Chris Bennett said.
"There's a reason they're 5-0. It showed tonight. We got the drive there in the first and after that they just shut us down."
Creekview did not punt until the first play of the fourth quarter, featuring balance with an effective ground and pass attack.
Hall, who started on his 18th birthday Friday night, dominated the contest by completing 11 of 15 passes for 237 yards and two touchdown passes. He also added 79 yards rushing on six carries.
"Hayden did a great job," Morrell said. "He's one of the team leaders and he reads the defense very well. He makes a lot of the calls at the line of scrimmage, both pass and run. He just had a great night tonight and executed very well."
Seniors stood out for the Grizzlies. The receiver duo of Hunter Udall and Joey Noll accounted for 167 receiving receiving yards. Noll's 41-yard touchdown reception in the third quarter was arguably the highlight of a highlight-filled contest.
Defensively, senior defensive lineman Trent Gilleland and Chris Mata each recorded sacks against the run-heavy Bulldogs offense.
With Creekview holding the No. 1 seed and Sequoyah locked in at No. 2, Forsyth Central will try to defeat Northview at home on Friday and secure a No. 3 seed for the region's play-in game in Week 10.


text:
<!DOCTYPE html>

<meta charset="utf-8">
<title>AstronomyLibs::Coordinates Examples (JS)</title>
<link rel="stylesheet" href="../css/styles.css">
<link rel="stylesheet" href="../css/examples.css">
<link rel="shortcut icon" href="../favicon/moon.png">

<?php include '../page_header.inc.php'; ?>

Coordinates

Uses the following functions:

AstronomyLibs_Coordinates_float2text

AstronomyLibs_Coordinates_text2float

Enter coordinates in either float form (e.g. 19.59475) or text form (e.g. 19° 16' 32.6") and have
it converted to its counterpart.

Set decimals for the float format (e.g. 3 decimals to get 19.595 for 19.59475) or for the
arcsecond part of the text format (e.g. 3 decimals to get 19° 16' 32.629" for 19° 16' 32.629285").

For conversions from float to text you can set the format of the text representation, for example:

19° 16'32.629"

19 16 32.629

19d 16m 32.629s

19h 16m 32.629s

Input allows negative values for degrees, as well as directions N, S, E, W (S & W being converted to negative float values).

            Float Coordinate
            Text Coordinate
            Format
            Decimals

            <input type="number" step="any" id="floatcoordinates" autofocus oninput="updateFloat2Text()" placeholder="Float">
            <input type="text" id="textcoordinates" oninput="updateText2Float()" placeholder="Text">
            <select id="format" onchange="updateLastChanged()">
                    <option value="symbols" selected>10° 20' 30.4"</option>
                    <option value="spaces">10 20 30.4</option>
                    <option value="dms">10d 20m 30.4s</option>
                    <option value="hms">10h 20m 30.4s</option>
                </select>

            <input type="number" min="0" id="decimals" class="shortinput" value="" oninput="updateLastChanged()">

redpajama_set_name: RedPajamaGithub


Support you blues activity! Consider a banner on The European Blues Union website and reach almost 5,000 blues lovers and professionals each month.
Side Banner: this appears on the right side of each page.
Please contact info@europeanbluesunion.com if you have questions.


text:
The 1000 Books Foundation is a Nevada 501(c)(3) non-profit public charity which operates the nationwide (and in Canada) 1000 Books Before Kindergarten challenge. The concept is simple, the rewards are priceless. Read a book (any book) to your newborn, infant, and/or toddler. The goal is to have read 1,000 books (yes, you can repeat books) before your precious one start kindergarten. The 1000 Books Foundation provides useful information and resources to parents and caregivers and enables libraries, schools, churches, and other non-profit entities to host 1000 Books Before Kindergarten challenges in their local community.
We provide an innovative, yet fun approach to establishing strong early literacy skills. Parents and caregivers keep track of the books that they read to their children. Parents and caregivers can use log sheets, journals, or even our iPhone and Android App to track their reading. We help parents and caregivers give their young children the confidence necessary to become strong readers and successful in school and life.
In addition to the 1000 Books Before Kindergarten challenge, the 1000 Books Foundation other projects include #TheBigRead (an annual one-day event that promotes reading just one book) and a very active social community on Facebook , Twitter, and YouTube. Not all communities are able to offer the 1000 Books Before challenge to their residents. However, we hope this does not dissuade parents and caregivers from taking the initiative to complete the 1000 Books Before Kindergarten challenge. All the materials necessary (e.g., log sheets, milestone markers, and certification of completion) to complete the challenge are available on our website for free. Even if you participate in your local community challenge, please join our on-line community.


text:
Stara Zagora becomes a smart city thanks to an innovation project
The implementation of the second phase of the project 'Modernization and Development of Sustainable Urban Transport in the City of Stara Zagora' will enable more efficient, environmentally friendly integrated urban transport, alleviated traffic, reduced use of private vehicles at the expense of the use of public transport.
It envisages the following activities and objects: "Reconstruction of overpass over railway line and Slavyanski Blvd., Patriarch Evtimii Blvd. and extension of the gauge of the roadway, Construction of a system for management of the urban transport," Introduction of automated system for charging and rehabilitation of the repair hall of a trolley depot. The Deputy Transport Minister Yordan Nikolov recalled that during the implementation of the first phase of the project, the bus and trolleybus parks in the city were completely renewed.
The contractor for the automated billing system is Telelink Business Services EAD, Sofia. The total value for execution of the contract amounts to BGN 3 437 463.00 excluding VAT for a period of 30 months. The system will facilitate the use of buses and trolleys and will improve the quality of passenger transport services.
Additionally, the introduction of such a system will eliminate ticket sales in the vehicle by service staff and help the operator to monitor revenue from tickets while preventing the gratis travel.
The expert team offers the installation of vending machines in all buses and trolleybuses, explained Stefan Malinovski, Head of Intelligent Systems Unit at Telelink. According to him, the second phase of the implementation of the urban transport modernization project in Stara Zagora will be another step towards building the modern "smart city".
In all vehicles there will be validators for electronic cards, which will be sold at 10 seats in the city as well as in the vehicles themselves. Electronic cards will also be issued.
The contract with the "Em Tran Sis", Sofia consortium for the construction of the Stara Zagora City Transport Management System, will be signed by the Mayor Zhivko Todorov. It includes video surveillance of 37 crossroads in the city with intelligent traffic congestion prevention system, control center building, traffic lights replacement, vehicle video surveillance, traffic management and traffic control system incorporating new traffic controllers with state-of-the-art technology , traffic detectors, traffic lights and devices, a system for giving priority to buses serving public transport. Ilian Valchev of the consortium specified that the system will have an adaptive module for agent which will collect and analyze huge base historical data including holding various city events, which will allow adaptation of modes and phases of traffic lights.
The value of the project is BGN 3 932 538.00 excluding VAT and the implementation period is 30 months.


text:
Biografia
Figlio di Salvestro il Chiarissimo (morto nel 1346) e di Lisa Donati, divenne padre di tre figli: Giovanni, Francesco e Antonia.
Il figlio Giovanni di Bicci de' Medici sarebbe poi diventato il primo membro storicamente rilevante della famiglia Medici di Firenze; alcuni ipotizzano sia il fondatore del Banco dei Medici. Il suo nome è quello del leggendario cavaliere Averardo, dal quale i Medici rivendicarono la discendenza

Figli
Averardo sposò in prime nozze Giovanna di Lotto Cavallini de Benaguisi e in seconde nozze Giacoma Spini. Ebbe tre figli:
 Giovanni di Bicci de' Medici, sposò Piccarda Bueri
 Francesco di Bicci de' Medici (morto nel 1402), sposò Selvaggia Gianfigliazzi e Francesca Balducci
 Antonia di Bicci de' Medici, sposò Angelo Ardinghelli

Genealogia

Ascendenza

Note

Bibliografia
  Brucker, Gene A. (1957). The Medici in the Fourteenth Century. Medieval Academy of America.
  Lee, Alexander (2014). The Ugly Renaissance. Hutchinson.
 .

Altri progetti

Collegamenti esterni
  Medici.
  THE MEDICI Genealogical tree.
 The Medici Family.
  Medici family tree.

Averardo di Bicci de' Medici

redpajama_set_name: RedPajamaWikipedia


Giancarlo Stanton going to the Yankees was a punch in the gut to all of the American League, but it was especially impactful on the Red Sox. However, as hard as it may have been to swallow the massive blockbuster deal, Boston general manager Dave Dombroski is aiming higher rather than wallowing in self-pity.
According to the Boston Herald, the Red Sox are looking to sign both free-agent outfielder J.D. Martinez and first baseman Eric Hosmer.
Dombrowski commented on the possibility of such a move Monday, but said it may be impossible to pull off.
"I don't know where we'd play those two bats," Dombrowski told reporters. "I'm trying to figure that one out. But I would say we'd be more limited to probably one bat. I can't say that - I guess if we went for a platoon-type guy or something somewhere else, but I don't really know where that second bat would play. Middle-of-the-order type. I mean you can get a better offense, but a middle-of-the-order type bat."
Then when asked again Thursday about the possibility, Dombrowski did not deny he was trying to make this move.
"No, would not comment on any free agents discussions," the Red Sox' general manager wrote in a text.
Signing both Martinez and Hosmer would cost an arm and a leg and possibly north of $300 million, but the Red Sox and Yankees often make moves to counter the other and this would certainly be a solid counterpunch.


Nostalgia Classic Cars is both a classic car showroom and a memorable venue for brands to host their events, providing a unique experience for visitors. The business was founded in 2016 by Mazin Al Khatib, an ex-banker who took his passion, coupled it with well-tuned business acumen, and now runs the complete operations of the firm. The showroom is a first of its kind in the UAE, focusing on selling a reasonably priced selection of famous models to those entering the hobby of collecting classic cars. In addition, the showroom brings together classic car enthusiasts from across the country to exchange knowledge and expertise with like-minded people. Being the creative hub in the region for new ideas, and pioneering in arts and culture, Nostalgia is strategically located at the Alserkal Avenue in Dubai. The company has a collection of over 100 classic cars priced in the range of $50,000 - $100,000. The premises of Nostalgia Classic Cars, better known as Nostalgia, is divided into two areas. The first area spans over 1,000 square meters and functions as a gallery with a lounge area and library. This area is also used for Nostalgia's themed exhibitions, and can be converted into any type of venue to provide ample space for brands wishing to host a themed event in Dubai's arts and culture district. The second section of the site is Nostalgia Warehouse. It is covering 1,000 square meters and serves as a full time showroom to display the company's complete stock to all kinds of classic car enthusiasts in the region. Next to it is the first of its kind Nostalgia Workshop which is specialized in restoring and maintaining classic cars. Nostalgia is also the only showroom in the region to provide its customers with after-sales services for classic cars. Whether this involves registering the car, further restoration or servicing, Nostalgia promises to be 'just a call away'.


(Yields about 30 cookies) Note: The dough can be made and shaped ahead of time and kept frozen for four to six weeks. The baked cookies can also be frozen for three to four weeks.
Using either a stand mixer with a paddle attachment or a hand mixer, beat the butter and sugar together until combined. Add the flour and cocoa in stages and mix until all ingredients are combined. Add extracts and combine until uniform.
Portion the dough using a 1/2-ounce scoop or kitchen spoon and roll each into a ball in your hands until smooth. Evenly space 12 balls on 11 x 17-inch parchment-lined baking sheets. Then gently press down on them to slightly flatten them into disks.
Bake for 12 to 14 minutes, or until the center seems slightly firm to the touch and the dough no longer looks wet. Remove from oven and allow to cool completely on wire racks.
Using a stand mixer with a paddle attachment or a hand mixer, cream together the butter and powdered sugar. Add milk and vanilla extract and beat until light in color and texture. Using the back of a spoon or a small offset spatula, ice one cookie with the desired amount of frosting and immediately sprinkle with peppermint candies. Repeat this process with each cookie; the icing will harden quickly. If the icing sets too quickly, simply scrape off, stir, and re-ice the cookie.


Neuro-linguistic programming is psychological approach of personal development that usually aims at changing the way you think or generally approach your life. The psychological approach aimed at changing the way you view things or think as part of personal development is known as Neuro-Linguistic Programming. The basis of this program was the observed connection between the neurological processes, linguistic and the programming process which refers to pattern of behavior as a result of previous incidents.
The strategies that successful people have used before are analyzed and later used by an individual in an attempt to realize personal goals. NLP generally is referred to as a process of learning the language of your mind and controlling your actions by taking control of your mind.
NLP practitioners or coaches are usually the people who offer training to individuals who want to take apply this process and want to do it right. Since NLP is aimed at improvement and positive results, some of the targeted areas of application are business, communication, making of everyday decisions, personal developments, and relationships among many more.
This therefore implies that NLP can be applied to assist in improving both on the professional and personal life aspects. Today the access of NLP courses is made easy to all as there are coaches and practitioners online who are ready to teach you and since it is online sessions, you save on expenses that would have otherwise been incurred such as travel expenses to attend a session.
Individuals with tight schedules or pressed time are also very good candidates of online NLP sessions since there will be no time involved in travelling to attend a session and you can be able to select your own convenient time unlike most offline sessions.
Someone in need of success or progress is one of the most ideal candidate for this course. Someone who is looking forward to being an NLP practitioner or coach is another ideal candidate for this course as they can teach more people when they have mastered the course.
An NLP trainer who would like to refresh their skills in this course due to various reasons such as staying for a very long time without practicing it can also be an ideal candidate for this course especially online sessions. We all have different preferences of how we want to learn and some people do well with just simple guidance while others need a hand throughout and you are free to chose a trainer who is ideal for you online.
NLP emphasis is usually on such areas as programming yourself for success in almost any situation, changing your thoughts and behavior for progress and programming your own mind.


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Download Justice Society: World War II (2021) [480p, 720p, 1080p] + Subtitle
Chukwuka Solomon May 11th, 2021 at 9:09 am
Justice Society: World War II (2021) Full Movie Download.
Download Justice Society: World War II (2021) [480p, 720p, 1080p] Movie Below:
Genres: Animation, Fantasy
Quality: 720p WEB-DL
Director: Jeff Wamester
Writers: Jeremy Adams, Meghan Fitzmartin
Stars: Matt Bomer, Stana Katic, Chris Diamantopoulos, Liam McIntyre
Synopsis: The Justice Society of America , a group of heroes aiding the allies in World War 2, acquire an ally from the future who sends them on an adventure that changes history.


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Elvis Presley is one of the most famous musicians ever. What happens when you take the music out of the equation and choose to focus solely on his movies? Enter Viva Pod Vegas: The Elvis Presley Film Podcast! Hosted by Joey Lewandowski and Mike Manzi, Viva Pod Vegas is a deep dive into the 31 films that Elvis Presley starred in, plus specials and some surprises. Uh, thank you very much for listening. Presented by the CageClub Podcast Network.
Viva Pod Vegas: The Elvis Presley Film Podcast Joey Lewandowski and Mike Manzi
Fun in Acapulco (1963)
We're headed down to Mexico -- without Elvis, though, and we'll explain why he isn't allowed to join us -- to talk about Fun in Acapulco! We're talking about *another* Elvis character named Mike, love triangles on (and off?!) screen, and Col. Tom Parker's soundtrack mandate (and how that will become the "new normal" for Elvis movies). Joey shares the craziest bit of Elvis movie trivia we've found so far (to which Mike wonders, "Why even make this movie?). We talk about Elvis's ability to sing in Spanish, him having fun again on screen, and the craziest Elvis character backstory so far. We discuss remaking Elvis movies, his first on-screen appearance with a cape, and an on-screen Col. Tom Parker stand-in. We also talk about how Fun in Acapulco gives us another huge Elvis song ("Bossa Nova Baby") and a Top Gun-esque ending and reconciliation. We try to make sense of our "forced songs" game scale and peek ahead to our next episode to brace ourselves for Kissin' Cousins.
It Happened at the World's Fair (1963)
We're entering 1963 and headed (via plane!) to Seattle for this episode about It Happened at the World's Fair! In this episode, Mike gets a crash course on various World's Fairs (and Diane Warren) while also playing a couple guessing games and coming up with some merch ideas. (He also caught "hair blindness" from Joey, but finds himself able to revel in the fact that Elvis's character is named Mike.) We talk about Norman Taurog's continue (literal) reign of terror, how nice the print for this movie looks, and how It Happened at the World's Fair is (unexpectedly) "the Kurt Russell movie"! We compare Elvis to Pepe Le Pew and Michael Jackson, praise his fight choreography, and urge filmmakers (long since dead/retired) to get Elvis into space. We discuss the caliber of music in the movie, admire Elvis's ability to act on screen with children, and discover some really exciting new ways to incorporate music into his movies. We wonder what the titular "it" that happened at the World's Fair is, why there are so many clowns, and what a particular Elvis joke means. Plus, we share some wild Baz/Elvis news!
Girls! Girls! Girls! (1962)
Viva Pod Vegas returns as we hit the open sea for Girls! Girls! Girls!, a movie that should probably instead be called Boats! Boats! Boats! After comparing Elvis's character of Ross Carpenter to Vin Diesel (again) and past Elvis characters, we call on Brian Rodriguez (High School Slumber Party, Uncle Francis's Wine Cellar) for an expert opinion on which Friends character E would play. Then, we dive into the Golden Globe-nominated (!) film to talk about passing the focus to other singers, behind the scenes drama, and whether or not the cast was in genuine danger while making this movie. We wonder what Laurel's backstory is (and explain why the movie should be about her), debate whether or not Elvis singing in Chinese is good or bad, and find ourselves in disbelief at the times the movie decides to cut away from the action. Joey's favorite Elvis song pops up, we talk about "The Implication" from Always Sunny, and we look ahead to Sofia Coppola's Priscilla. But, most importantly, we spend a long, long time talking about "The Walls Have Ears," which is the greatest Elvis cinematic scene to date.
Kid Galahad (1962)
Two episodes of Viva Pod Vegas in one month? Unprecedented! We're back with another one of Elvis Presley's 1962 films, and this time we're talking about his stint as a boxer in Kid Galahad! In this episode, we compare Elvis to Nicolas Cage (or vice versa) and Dom Toretto before we wonder, what exactly *is* a musical, anyway? Joey's brain actually works (for a change), allowing him to make a deep cut connection. We talk about Elvis as a boxer (who can sing, too?!), on-set tensions between Elvis and Charles Bronson, and whether or not Kid Galahad hints at the same kind of seediness other Elvis movies have hinted at before. We compliment the boxing cinematography, debate how hard it is to write movie-specific songs, and look ahead to (possibly) our first dud in Girls! Girls! Girls, the next movie we're set to cover.
After our recent time warp to cover Baz Luhrmann's Elvis, we're back on the original timeline and talking about Elvis Presley in Follow That Dream! But... is homesteading a dream? We have questions! We talk about how we've been duped (yet again) into thinking every remaining movie is a musical, how weird this movie is in particular, and how terrible Elvis's character's name is. We discuss how Follow That Dream shows Elvis (once again) falling in love with a familial relation -- even though he isn't girl crazy -- and why this movie is so horny. We also share a Tom Petty connection, talk about toilets for a while, and lament the lack of a real EP being available for this movie. Plus, we begin to look at these original Elvis movies through the lens and lessons learned by watching Baz Luhrmann's Elvis. Is Pops in this movie a stand-in for the Colonel? Maybe!
Baz Luhrmann's Elvis (2022)
It's a Viva Pod Vegas / #HANX for the Memories special crossover event as we talk about Baz Luhrmann's Elvis, the Elvis Presley biopic! We discuss Austin Butler's portrayal of Elvis (and how he is the movie), Tom Hanks's portrayal of Colonel Tom Parker (and why he took the role), and Baz Lurhmann's novel take on the biopic via a new POV. We talk about Hanks's makeover and his level of "going for it," the movie's frenetic pacing and structure, and how it navigates around some controversy. We also wonder if Riley Keough would have fit in the movie and try to picture Tom Cruise as Colonel Tom.
℗ & © 2019 The CageClub Podcast Network
calielvisgirl , 08/22/2022
Love your sense of humor !!
Long time Elvis fan - my interested was reenergized by the new Elvis movie. Love this podcast it's funny and charming and you can see a love and respect for Elvis. My only concern is the lack of basic knowledge about Elvis biography (historical dates and personal life) and also vintage movie trivia. That Touch of Mink you mentioned in latest movie is very famous Cary Grant / Doris Day movie. I expect more knowledge of movie trivia of the era. Other then that - love it. Love the Fast & Furious references and Con Air.
jademarie24 , 01/16/2023
Change of Habit
Please talk about the great movie Change of Habit, it starred Mary Tyler Moore. It was a more dramatic part for Elvis, and rumored to be his favorite.
Ciglesias95 , 08/10/2022
Fun Banter and Interesting information!
I fell down an Elvis rabbit hole after watching the Baz Luhrmann movie and wanted to know more about the icon since he was way before my time.
I always knew of Elvis and his references in pop culture, especially his connection to Las Vegas, but anything beyond that drew a bit of a blank for me. The movie could touch on so much and this podcast fills in a gap for those curious about his movie career. I like how each episode dives into the plots and roles he played in all of his different films and what was going on in his life during the making of it. The trivia is very interesting and sheds a light on a lot of Elvis lore you hear. I find myself laughing out loud quite a bit with all the jokes and references listed along the way.
If you are curious about Elvis's career in cinema or just curious about his life and want to know more about him, this is definitely a fun podcast for you!
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On Saturday, July 9th, three puppies starving in an abandoned house in Northampton County, NC were transported to safety in Middletown, DE by Doobert.com volunteers.
Northampton County Animal Control found the emaciated puppies in an abandoned house. The past owners of the house received warrants for the mistreatment of the puppies.
It Takes a Village Animal Rescue and Rainbow Animal Rescue of North Carolina came together to care for the pups until they could be transported to their new rescue. With the help of the community, they received enough donations to care for the unhealthy puppies and prepare them for their trip. Rusty Miller and Terri Allen, volunteers of Liberty Ride Transport, coordinated the journey for the pups up to Middletown, DE.


Our family just got back from Bonaire and had a fabulous time and just loving Kids Sea Camp. Your crew, as usual, do a great job hosting the week and everyone seemed to have a really great time!! We are all thinking about where to travel to next year. We have quite a large group of people that are all interested in finding a place for us all to travel to next summer. Many of us still have small kids so we really all want to still do a camp with you. The kids simply love Kids Sea Camp!! Thanks for another great week & look forward to another trip with you soon!
Josh and Wendy, Grant, Reed, Clair and Katie. We love kids Sea Camp & Family Dive Adventures.
The dive weeks our family have done with Kids Sea Camp: Costa Rica, Bonaire, Grand Cayman, Bay Islands Honduras, and Utila.