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The top 10 highest paid biopharma R&D executives in 2018
The top R&D executives from across biopharma are certainly not looking down the back of the sofa for change; most are earning around $7 million a year. (AstraZeneca)
The top research and development executives from across biopharma are certainly not looking down the back of the sofa for change; most are earning around $7 million a year (including compensation, pensions, stock and so on).
But then the job is tough, and arguably just as important as the top CEO job, given how much companies rely on the strength of their R&D. You would think that this list would, broadly at least, tally with the top 10 R&D budgets, but that's not quite so.
Regeneron doesn't even figure in the top 10 R&D budgets for 2018, yet George Yancopoulos, M.D., Ph.D., is once again at the top of the pay league table, with an almost unimaginable $25 million-plus package, around 2.5 times the average of the big players.
Is Regeneron particularly innovative in comparison to its peers? Looking at the metrics, it's right up there, and Yancopoulos likes to talk up how the biopharma is a hardcore innovator and shaming those that rely on price hikes and me-too drugs.
True, a lot of Yancopoulos' pay is tied to major blockbuster and aging eye drug Eylea, but he's been there two decades and has helped the company convert a high hit rate from its R&D work into NMEs.
There is some dovetailing: Johnson & Johnson, the second largest R&D spender overall (including diagnostics), is also second on the pay list, with Chief Scientific Officer Paul Stoffels, M.D., taking home more than $10 million, though this comes at a time of major legal tussles around claims of asbestos in talcum powder and ongoing opioid litigation.
One of the more surprising is Novartis, fourth on the R&D spenders' list but tenth for R&D executive pay packets. Its research head, Jay Bradner, M.D., who's been there for around three years, is helping steer the company into new areas (and slashing areas that don't keep up), but has also seen a number of failures, including partnered flops in Alzheimer's and NASH.
There have also been changes at the top, with Biogen's R&D lead Michael Ehlers, M.D., Ph.D., the most notable, jumping ship for a biotech just a few months' back, coming off the back of a pretty woeful pipeline that this year saw one of its biggest hopes, its much-hyped Alzheimer's hopeful, implode.
For more eye-watering paychecks and the microcosm of biopharma's R&D world, check out our top 10 below. — Ben Adams
1. George Yancopoulos, Regeneron
2. Paul Stoffels, Johnson & Johnson
3. Michael Severino, AbbVie
4. John McHutchison, Gilead Sciences
5. Mikael Dolsten, Pfizer
6. Michael Ehlers, Biogen
7. Thomas Lynch, Bristol-Myers Squibb
8. Roger Perlmutter, Merck & Co.
9. Hal Barron, GlaxoSmithKline
10. Jay Bradner, Novartis
Book traversal links for The top 10 highest paid biopharma R&D executives in 2018
1. George Yancopoulos, Regeneron ›


Malawi University of Science and Technology-MUST has launched the Innovation Scholar Program-ISP that will see scholars engaging in research that has an impact on the lives of people in the country.
iMoSyS, an upcoming ICT company in Malawi is representing the country at this year's ITU Telecom World 2018 Summit under the theme "Innovation for smarter digital development" from 10th to 13th September, 2018 in Durban, South Africa where the Malawian company will exhibit its innovations.
South Africa has unveiled a new super radio telescope that will study galaxy formation, a first phase of what will be the world's largest telescope in a project to try to unravel the secrets of the universe.


Does it? The ext/gd/libgd/ was always distributed with GD license. And the only file which has extra license header is gd_xbm.c (not yet merged), see my mail to Marcus.
Hm, right, just checked the code again and you are totally right.


Local construction capacity must be utilised first wherever possible, stated the Construction Industries Federation of Namibia this week when it offered a range of criteria it feels must be applied to government procurement.
With regard to citizenship, the Construction Industries Federation (CIF) proposes that any contractor with less than 100% Namibian ownership for contract values of up to N$10 million should be disqualified immediately. For contract values from N$10 million to N$50 million, a minimum of 50% Namibian ownership should be required. This should also be relevant for any joint ventures, where each partner in the undertaking should meet the minimum requirement to qualify. If joint ventures are not scored separately, a minimum of 100% Namibian ownership should be a requirement for contract values up to N$50 million.
The CIF also recognises that citizenship can not be the only criterion. Other factors that should be taken into consideration are the shareholding of previously disadvantaged persons, women, the youth and the disabled, the ratio depending on the size of the project.
Other important criteria are the financial strength and the technical skills and experience of the bidding entity, which become more critical with the increase of the size of the project. Established, large and major contractors should also be scored on their contribution to skills transfer.
The CIF stated that it has designed such a framework to categorise contractors and that this was presented to the Ministry of Finance in the past.
To avoid middle men or tenderpreneurs, the federation said it would be important that the combined citizenship of directors and senior management of the bidding entity or entities is also taken into consideration. Additionally, contractors must be able to furnish proof of the successful completion of previous projects to prevent foreign contractor paying front men to do the bidding.
"We believe that we need to look at all these criteria holistically in our adjudication of tenders. Currently, the playing field is not in favour of Namibian contractors who often can not compete on price. However, we need to maintain local capacities to secure their continued contribution to Namibia's economy. The more we engage local, the more we develop and empower our own people" concluded Kirchner.
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Luminescent mix of colors on strong, sturdy stems making them superb cut flowers. A nice selection for the border and cottage garden. Flowering in summer around 24 inches tall with 5 inch wide flowers.
Sow outdoors, Germination in less than two weeks at 60F in dark, Can be started indoors too but be careful transplanting, USE PLUGS. Best sown in situ.


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Aasiaat (oude schrijfwijze: Ausiait, Deens: Egedesminde) is een voormalige gemeente in Groenland. Aasiaat omvat verschillende eilanden in het zuidelijke deel van de baai Qeqertarsuup Tunua, het is een archipel. De dorpskern ligt op ongeveer 68°43'NB en 52°53' WL.

Aasiaat was tot 2009 een eigen gemeente en een van de twee gemeenten die niet op het vasteland lagen, de andere gemeente was Qeqertarsuaq. De bevolking bedroeg op 1 januari 2005 3310 inwoners op een oppervlakte van 4000 km². Dat maakte dus een bevolkingsdichtheid van 0.83 inwoners per km². Per 1 januari 2009 ging de gemeente op in de nieuw gevormde gemeente Qaasuitsup.

Geografie
Het grootste eiland van de Aasiaatarchipel is het onbewoonde Saqqarliup Nunaa. Er staan wel enkele huizen, maar deze dienen om de toeristen een overnachtingsplek te geven. Op het westelijke uiteinde van het eiland bevindt zich het verlaten dorp Manermiut.

Tot de voormalige gemeente behoren de dorpen :

1. De stad Aasiaat, bevolkingsomvang 3100, op het gelijknamige eiland, iets ten noordwesten van Saqqarliup Nunaa.

2. Het dorp Akunnaaq (Akúnâk), bevolkingsomvang 101, op het gelijknamige eiland, iets ten noordoosten van, 23 km verwijderd van de stad Aasiaat.

3. Het dorp Kitsissuarsuit, 109 inwoners, op het kleine gelijknamige eiland (in het Deens is Hunde Ejland de benaming voor zowel het dorp als het eiland), 21 km noordwesten van de stad Aasiat (in oostnoordoostelijke richting).

Een ander verlaten dorp is Vester Ejland op het gelijknamige eiland, het meest westelijke eiland van de archipel op zo'n 29 km van Aasiaat (in westzuidwestelijke richting).

Voormalige gemeente in Groenland

redpajama_set_name: RedPajamaWikipedia


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Washington H. Soul Pattinson flies the coal flag and tells concerned shareholders to "sell their shares"
"We continue to believe in the long term need and demand for coal" the CEO of Washington H. Soul Pattinson (WHSP), Todd Barlow told shareholders at the company's annual general meeting (AGM) in Sydney today.
It quickly became clear that climate change was a hostile topic for the investment house, which has a diversified portfolio including a 25% stake in TPG and a 50% stake in New Hope Group (a coal mining company that bought the Bengalla coal mine in August 2018). Chairman Robert Millner grew increasingly irate throughout the AGM after being questioned on global warming and its associated risks.
When asked by a shareholder if he believed in climate change Millner, who is also the chairman of New Hope, replied in frustration: "I'd like to ask you the same question as well. It's a very difficult question to answer, and I'm not prepared to get into a political debate here about the pros and cons of what people think about climate change." Watch the exchange below:
It's not a difficult question for scientists though. There's near total consensus we are in the throes of a global warming catastrophe; one that will magnify if we fail to limit our consumption of coal.
Pushing the coal agenda
Millner told the meeting that the coal WHSP is exporting will be burned in "new modern coal-fired power stations that are at least 50% under the Paris emissions," later calling it "cheap" and "clean".
According to the executive director of the International Energy Agency (IEA), "we have no room to build anything that emits CO2 emissions," a statement also consistent with peer reviewed literature from Oxford University researchers.
So what do Millner's comments actually mean? Not much for limiting climate change, but they do show WHSP is heavily invested in the idea of coal as a long term asset.
And that could be risky. As carbon-generating forms of energy face increasing regulations to cap climate change, investors are becoming concerned about the potential financial implications.
It was these risks that shareholders wanted to know about. Millner refused to answer their questions in a civil manner however, howling "If the shareholders aren't happy they can sell their shares!". Watch below:
In his CEO's address Barlow noted 'there's currently over a thousand coal fired power plants that are either under construction or in the planning stages, in the world." Millner later told shareholders "of interest they've built 725 new coal-fired power stations, and there's another 1000 on order" later calling it "cheap" and " clean."
This figure is nowhere near accurate and builds on the misinformation about this issue spread by pro-coal commentator Andrew Bolt and government backbencher Craig Kelly. Kelly last year confused the number of coal powered units being built with the number of coal powered plants – significant difference when you consider that Liddell power station in NSW consists of four units.
According to the latest data, there are 708 coal power stations under construction and in the planning stages, a far cry from the "over a thousand" suggested. Further, the number of coal power stations actually built will be much less than stated, with Carbon Brief calculating that "the pre-construction pipeline has fallen two-thirds since 2015."
The chairman finished his diatribe by telling shareholders who were concerned about the catastrophic consequences of climate change: "I don't know how you people can sleep with yourselves at night!"
Perhaps Millner should ask himself the same question.
Is your hard-earned superannuation invested in dirty coal like the Bengalla mine? Find out by using our super funds and fossil fuels table.
Tags:AGM, annual general meeting, carbon budget, climate change, climate risk, coal, coal mining, disclosure, divestment, fossil fuels, global warming, Paris Agreement, shareholder activism, shareholders, TCFD, Washington H. Soul Pattinson

redpajama_set_name: RedPajamaCommonCrawl


A voter casts his ballot in Georgia's 6th Congressional District special election at a polling site in Sandy Springs, Ga., Tuesday, June 20, 2017.
Two separate polls of likely Democratic and Republican primary voters were conducted in April.
In the latest episode of the Politically Georgia podcast, host Greg Bluestein and AJC Washington correspondent Tamar Hallerman analyzed the results.
The Atlanta Journal-Constitution and Channel 2 Action News commissioned the University of Georgia to conduct the polls.


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All Manchester University Press publications are subject to a process of rigorous peer review, and we take pride in our production values and author relationships.
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A gorgeous balloon perfect to reveal the gender of your baby to the world. This balloon is stuffed with soft blue feathers and finished with a baby blue curling ribbon. The balloon is helium filled. When the recipient opens the box,the balloon will graciously float out of the box. The balloon will be wrapped in tissue papers and will be delivered in a brown box with pretty balloonzest ribbon.A tag is tied at the base for your personal message. You can personalise the message on the balloon with no more than 30 characters.Please contact us for this.
float time : at least 2 weeks.


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YouTube Star Gigi Gorgeous Marries Nats Getty
Posted on July 13, 2019 in Story
YouTube Star Gigi Gorgeous is married!
The 27-year-old Canadian beauty influencer and activist, who became even more famous in 2013 after coming out as a transgender woman, has wed Nats Getty.
Gigi, aka Giselle Loren Lazzarato, wed the 26-year-old model, fashion designer and LGBTQ+ activist, aka Natalia Williams, on Friday in a beachfront wedding at the Rosewood Miramar Beach in Montecito, California. Gigi sported a white strapless custom Michael Costello ball gown and cathedral-length veil at the ceremony, while Nats sported a long white suit she designed from her own label, Strike Oil, People reported.
Gigi's father David Lazzarato walked her down the aisle as an instrumental version of Céline Dion's 1996 ballad "Because You Loved Me" played, as seen in a video posted by guest and fellow YouTube star Trisha Paytas.
"My daughter's getting married today!" he said excitedly hours earlier, as seen in a video posted on Gigi's Instagram Story.
Gigi later changed into two more Michael Costello outfits throughout the day, People said. She sported a white halter mermaid gown to the reception, which was held in a banquet hall with tables adorned with candles and elaborate white and pink rose centerpieces.
Famed celebrity wedding planner Mindy Weiss planned the event and also officiated the ceremony, People said.
Other celebrity guests included fellow YouTube stars Kandee Johnson, Hannah Hart, Grace Helbig, plus actress Teri Hatcher and singer Bonnie McKee, who also performed, the outlet reported. Nat's cousin and Lord of the Flies actor Balthazar Getty also attended. The two are great-grandchildren of late oil tycoon J. Paul Getty.
Gigi and Nats met in 2016. That year, Gigi came out again, this time as a lesbian. She and Nats and got engaged in Paris in 2018.
"I'm Gigi's number one fan, so everything that she does I think it's like, the best ever," Nats told ABC News earlier this year.
The two want to have kids. But Gigi had her sperm tested late last year and discovered she had a low count.
"If I could get pregnant, I would get pregnant, in a minute," Gigi told ABC News. "I would do it. And I would love it. But that's something that God just didn't give me and I'm gonna have to find a way around it."
"We're gonna make it work, and it's gonna be amazing," Nats said. "I can't wait to see what kind of family we get to build together."
Sumber: http://www.eonline.com
Tags: Story
The Complicated Reality Of John F. Kennedy Jr. And Carolyn Bessette's Short But Legendary Relationship
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This topic contains 2 replies, has 3 voices, and was last updated by JasonR 9 months, 2 weeks ago.
Apologies for the slow update to the website; there appears to have been server issues. I am not sure everything is fully resolved, still some error messages but at least I can update things now.
Presumably no one is willing to give any thoughts as to their Mediterranean warm swim or sweltering run at Worthing Tri? Surely someone is willing to help me out, all it needs is a paragraph or two!
just read your message above. I thought that as there were so many members racing Worthing and that i tend to write a report every week that i'd give somebody else a go. I find it hard to believe the club has so many members and so few contribute to the weekly reports. These reports are a great way of finding out about events to do in the future,and as an event organisers they give a great insight into the expectations of competitors.


For questions related to membership applications (including status), or registration for an event, contact Betsy Harkins at [email protected].
For questions related to the mission and activities of the NFMA, educational programs, sponsorship, or to contact the Board or any of its officers or committee chairs, contact Lisa Good at [email protected].
To contact the NFMA by phone, call 412-341-4898.


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Reaction to the latest development in Ukraine
As the situation in Ukraine unfolds, we remain focused on our investment process: being active, long-term investors in companies with strong balance sheets and solid fundamentals, employing our research intensity capabilities.
As with other major geopolitical situations we anticipate there will be volatility in markets and while we invest with conviction we do not ignore the impact of globally-driven events on the companies and industries in which we invest, in addition to the impact on economies more broadly. Furthermore, we incorporate these considerations as part of our responsible investment approach, providing stewardship of assets which support the welfare of society.
We are already seeing a risk off sentiment across emerging markets, as the possibility of imposed sanctions increases, although Russia and Ukraine together comprise around 3.5% of the Emerging Market Debt hard currency index.
Our Global Emerging Market equities portfolios have c.4.5% investment in Russian companies1 with minimal exposure to Ruble-denominated names.
From a credit perspective, most Russian companies are at the lower end of Investment Grade ratings and could be downgraded to High Yield as a result of sanction risks.
We expect to see an increase in energy prices and grain prices across emerging markets which is likely to have an impact on commodities globally.
We will continue to monitor the situation and ensure that we actively manage our portfolios responsibly and maintain a global perspective.
William Davies
EquityEquity - GlobalEquity - Global Emerging MarketsFixed incomeMulti-Asset
1 Source: Columbia Threadneedle Investments, Bloomberg, as at 24 February 2022
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In Credit Weekly Snapshot – January 2023
Our fixed income team provide their weekly snapshot of market events.
Read time - 3 min
Steven Bell
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Some good news ahead for the UK and Europe
Steven Bell, our Chief Economist EMEA, looks ahead and suggests a brighter outlook for the UK and European economies.
Watch time - 5 min
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As signatories of the Net Zero Asset Managers initiative, we are adopting a Stewardship-led approach to delivering our net zero commitment.
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If we throw a light on Christianity we will see that it was the first major source to look upon humanism. Services like schooling and medical care were provided by the churches. The origin of western culture emerged from Christianity. It is really important for Christians to support Christian movies as it is the source of powerful feelings like love, faith, justice, birth, and death.
If you want to see the world from a positive aspect than Christianity is one which will make you optimistic. If we talk about Christian movies than we would find that Christian films are more popular today than ever.
Just imagine the message of the gospel is put into a movie. It is cool how the hearts of people change just by watching a Christian movie. The people who are the haters of God, even they change. Though God does not live with us he not dead. There are movies with a big budget but do they give any social message or gospel message?
If you are tired of watching movies which have inappropriate content for audience of all ages, you can just switch your mood towards online Christian movies. Christian movies have brought back the essence of truth and moral values which was lost.
Paying on movies which are not true, right, noble, and lovely and many more other things but paying for movies which contain all these elements is worth. People judge easily people belonging to other religion but Christianity is the one religion who teaches people to love and not to discriminate on the basis of their gender, race or class.
These Christian movies will teach you how to live with god even in today's world. You can really connect to god by watching Christian films. Christian filmmakers are increasing and also the quality of Christian movies is also increasing with inspiring messages.
It is not that the reason behind the low quality of Christian movies is that it does not release in theaters. You can watch Christian movies on Christian movie channels also. Christian movies do not get released in theaters due to financial conditions because very few people like to watch them which do not completes the budget of the movie. This is the reason why these movies are released online, on Christian channels or in DVD. So, believers of faith should be capable of filling those seats in theaters to make the movie successful in the film industry.
When you have a chance to light the glory of the god than you must let it go waste. To make Christian movies more popular you can go and watch them in theaters. To bring the glory of the god back to earth there is no more a better way than Christian movies. There is no religion barrier for watching a Christian movie. So, don't think go and get your tickets, have popcorn and enjoy your movie.
Thanks to smartphones, tablets, and other devices, watching Christian movies is now quite convenient. These movies are available at an affordable rate so you can watch good movies without paying extra upfront.
Christian movies provide entertaining and fulfilling pastime to everybody. People do not have to watch unnecessary stuff, and can choose to learn something while enjoying their leisure time, thanks to Christian movies.


Regenerative Medicine is an upcoming branch of modern medicine. It is a futuristic specialty and holds a lot of promise. If things go well, the research studies being carried out currently can change the way diseases are treated in the future.
Stem cells are the basic cells from which the immune system, blood system, and various tissues and organs develop. These stem cells are found in abundance in the umbilical cord of the baby. Researchers believe that these cells from the umbilical cord can be collected at the time of delivery and stored under special conditions, and the process is known as cryopreservation. They can later be used to treat a variety of diseases regarding the child or other blood relatives.
A human being is born with the natural resources to cure diseases. These resources are found in the blood in the umbilical cord and the tissues of the cord. These cells have the ability to cure several diseases like osteoporosis, blood cancers, diabetes, etc. -based on future research.
Repairing or re-growing the damaged tissues and replacing them in the human body is a relatively new area of research. The stem cells obtained at birth are perfect in this scenario. As of now, most of the replacing or transplant operations undergo failure as the body's immune system doesn't accept the foreign tissue and rejects it. The stem cells are the body's own cells and hence regenerated tissues grown from these cells will not be rejected by the body, say the scientists.
The concept of stem cell banking is gaining lots of awareness and more and more couples are opting for it.
There are several doctors and couples who do not advice stem cell banking. The point of argument for them is that the cost of storing the stem cells is too high and that it is still in its basic stages with no guarantee that there will be positive developments in the field.
Parents who opt for stem cell banking, though, argue that they will not take any 'risks' when it comes to ensuring their child's future!


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Home/Videos/National Allegiance - Videos/Will People Heed Dr. Ben Carson's Warning About Trump Protesters?
Will People Heed Dr. Ben Carson's Warning About Trump Protesters?
BCN Senior Editor March 14, 2016	National Allegiance - Videos, Videos 2 Comments
Dr. Ben Carson made big news last week when he dropped out of the GOP presidential race and endorsed opponent Donald Trump. Now Dr. Carson is warning people about violence that could escalate at Trump rallies and what's at stake. An excerpt from USA Today:
"If the protestors continue with their Alinsky-ite tactics, there is a real possibility of escalation because those who are the victims of them have two choices: they can submit to them and meekly just do whatever those protesters want them to do, or they can fight back," Carson, a retired neurosurgeon, said on NBC's Today Monday. "And if they decide to fight back, there could be an escalation."
Trump, who canceled a rally in Chicago Friday because of violence between supporters and critics, has said he bears no responsibility. He blamed supporters of Bernie Sanders. Trump's rivals, however, say the violence is a product of his angry rhetoric, such as statements that he would like to punch a protester in the face and that he would pay the legal fees of supporters who strike back.
Dr. Carson said the other candidates should stand up for the First Amendment. Disruptive protesting interferes with this right.
"The problem is that there are those who are being taught that if someone disagrees with you, you have the right to interfere with their First Amendment rights, their ability to express themselves, their freedom of speech," he said. "Now when people do things wrong such as that, it causes other people to react in a way that is negative, and therefore you see that reaction."
Protesters will continue to try to shut down Trump rallies. Dr. Carson said the left is just angry because Trump is standing up to them.
Tags Dr. Ben Carson President Donald Trump
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Les F
I think since Dr Carson has come out in support of Trump I no longer consider his opinion about anything. I support the First Amendment and he has the right to support the person he chooses but I do not support Trump for the fact that I think he is playing America for dupes. Sorry Dr. Carson I no longer consider your opinion of value.
Brother Tony O | WhyBenCarson.net
The deep divide has been growing wider and deeper for a quarter century. The electoral maps of the '80s were one color. The left had to fight back. The elder Bush gave them an opening with "read my lips". They got him to compromise on taxes. Bush-hater Ross Perot gave the (children of the sixties) Clinton's two election victories. Then came the dimpled chads… 9/11… war in Iraq +… and overseeing it all has been the money class looting our great-grandchildren's piggy banks.
What do I think? I think we are just seeing the pre-season. The two wings are crossing from tolerance through dislike and over into hate. The most likely outcome, war is coming. The wheels are going to come off of this runaway vehicle on which we ride.


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Arslanbob, kirgisiska Арстанбаб, är en stad och dalgång i Kirgizistan. Den ligger i provinsen Zjalal-Abad Oblusu, i den västra delen av landet, och är också namnet på dalen och på den valnötsskog som ligger i stadens närhet. Valnötter från Arslanbob var Kirgizistans första kända exportvara. Skogen är den största relikta valnötsskogen i världen och växer på mellan 1 500 och 2 000 meters höjd på sydsluttningen av Ferganabergen, som är en utlöpare från bergsområdet Tianshan. Staden Arslanbob ligger  meter över havet och antalet invånare var  2009.

Befolkningen är huvudsakligen uzbeker med färre än fem procent kirgizer, ryssar, tatarer, tadzjiker eller tjetjener.

Flora
Arslanbobs skogar producerar 1 500 ton valnötter per år. Valnötssäsongen börjar i slutet av september och är ungefär en månad lång.

Valnötsträden har en livslängd på ungefär 1 000 år och ger olja, protein, anti-oxidanter och omega-3-fettsyror. Förutom valnöten ger trädet trä för möbeltillverkning och annat hantverk. Vid sidan av valnötsträd, Juglans regia, finns det gott om andra vildväxande fruktträd i skogarna, till exempel äppelträd av arten Malus sieversii, päronträd av arten Pyrus korshinskyi och körsbärsplommon av arten Prunus sogdiana.

Historik
Valnötsträdet förekommer naturligt i en stor del av Centralasien. På Alexander den stores tid var valnötsskogen känd för sin goda jakt. Han tog med sig valnötter från Sogdiana, vilka kom att början den europeiska valnötsproduktionen. Alexander den store ska också ha fört med valnötsplantor till Grekland från sitt erövringståg i Centralasien. Det förklarar benämningen "Gretski" för valnötter i det ryska språket. Det har gett valnötterna smeknamnet ″grekiska nöttter″.

Etymologi
Arslanbob är uppkallat efter Arslanbob-Ata (eller Arstanbap-Ata), som levde på 1000-talet och egentligen hette Salman Abdul Rahman. Han var militär ledare men också naturvetenskapligt intresserad och den som planterade den valnötsskog som nu växer i området. Han kan ha varit av arabisk härkomst, där det arabiska Aslan översätts "lejon" och bab "port", medan på turkiska ata betyder "far till" - alltså "faderns till lejonporten". 'Bob', som suffix, har syftat på "resenär" eller "utforskare".

Referenser

Noter

Orter i Zjalal-Abad Oblusu


5 Cool Things No One Ever Told You About Nighttime Breastfeeding I learned a few things from this article, too!
15 ways to reduce pain during childbirth – but here's the catch: They are all things you do well BEFORE labor! Bet you didn't know that what you do beforehand can make a difference in the pain you might feel!
This is a nice summary of HELLP Syndrome and its effects on pregnancy. It's rare, but I've seen it happen a few times and it is not a good thing. In the initial stages, moms often don't realize anything is wrong.
Want to hear one doctor and IBCLC's take on normal weight loss in newborns? It's a bit technical, but very evidence based and reassuring to moms worried about their baby's feeding.
I had my first baby 20 years ago this week. And I *still* remember how difficult the summer was while pregnant! Found this article on ways to beat the heat while pregnant.
Musings from Mama Birth on Channing Tatum's experience with childbirth and a car commercial. Worth the read!
"Birth Story: Ina May Gaskin & the Farm Midwives" Official Trailer from Birth Story on Vimeo.


Dr. Azzam was pleasantly professional. I felt completely at ease with him and thought his communication skills were excellent. He offered an opportunity to ask questions and express concerns. He gave a solid plan of action, followed up by written suggestions. I would not hesitate to visit him again, should the need arrise.


The Hudsonville clinic opened on November 3rd, 2013. The Hudsonville location serves the surrounding areas of Jenison, Jamestown, and commuters between Holland and Zeelend. This office has been an active member of the Hudsonville Area Chamber of Commerce for three years. The Hudsonville clinic provides a variety of physical therapy specialties including custom orthotic assessments.


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Live Blog — Notre Dame vs. Michigan State
By Keith ArnoldSep 21, 2013, 2:30 PM EDT
There's perfect football weather in South Bend on this last day of summer. Notre Dame and Michigan State, two teams that have been playing each other since 1897, are set to square off for the 77th time, battling for the Megaphone Trophy.
As usual, you'll have plenty of options to watch and follow along. A national broadcast on NBC, beginning at 3:30 p.m. ET. A pregame show live from Notre Dame Stadium on NBCSN beginning at 3:00 p.m. And a live-stream of the game here at NBCSports.com, with HD video, a built in DVR, and an embed of our live-chat, available all around the world.
Both Brian Kelly and Mark Dantonio expect a slugfest this afternoon. We'll be here all game, chatting with a few thousand of our friends. Stop by, stick around, do whatever you'd like. But make sure you try and enjoy another classic match-up between the Spartans and the Irish, where eight of the last 13 games have been decided by less than a touchdown.
Notre Dame vs. Michigan State


text:
Storm Hannah holds no fear for Squirrels
Lindsay Cook during the Ashridge Boundary Run
Helen Nuttall ran the Reading half marathon on Sunday. She said "There was loads of support on the course, a couple of steep climbs, but a nice race, well marshalled and well organised (with free massages at the end!). I was very apprehensive and a little scared about trying to race after all my time off with surgery etc, but once I started was so happy to be out actually racing and trying to push the pace. I was 10 mins off my PB, but it's all relative and with the circumstances I'm immensely happy with a 1:36:17. More than anything it has given me a confidence boost that I will get back to where I was (and hopefully faster!!)."
Slightly closer to home Elwyn Howell ran a very muddy Welwyn half marathon, taking fully 10 minutes of his PB, finishing in 2:10:26.
Adam Bowler was first across the line for the club on Sunday in the Fleet half marathon, an England qualifying race. He finished in 14th place in 1:12:36, a PB. In perfect weather conditions Caroline Thrussell was thrilled to also run a 2 minute PB, finishing in 1:36:28, a new club record in her age category, but not quite fast enough for an England vest. Other finishers were Edward Price (1:17:58), Darren Matussa (1:25:14), Katie Harbon (1:28:56), Astrid McKeown (1:29:43), Paula Adams (1:30:48), Helen Cairns (1:41:10) and Jane Clarke (1:50:07).
Several North Herts Road Runners ran in the Milton Keynes Festival of Running. In the 10k race, Lorna Chambers was really pleased with her effort resulting in a time of 1.01.30, a 6.5 minute improvement on her debut 10K at Sandy last week. James Keogh said "Between the howling winds on Saturday and the hail storms after the race it definitely caught the best of the weekend weather. Not to say that there weren't some blustery headwinds at points" James fininshed the half in 1:33:41. He continued "Owing to injury I'm only just getting back to this kind of distance so was pretty pleased with my time all things considered." Other finishers were (10K) Clare Hooley (1:11:34). Half marathon, John Rayner was 11th in 1:21:28, Sophie Thrussell finished in 1:40:23, Ali Mottram in 2:35:24 and Jim Marvell in 2:35:25. Jim said, "It was my first half and I'm absolutely chuffed with my time of 2:35:24. (I'd been hoping for 2:45 or so!). The course was more scenic and a little more undulating than I'd expected. The last couple of miles were particularly tough but I found a small reserve of energy for the all-important sprint finish." One brave Squirrel tackled the 20 mile course - Adam Wilson finished in 3:25:05.
Three runners completed the Ashridge Boundary Run in the Chiltern Hills. Linda Aird said "the 40+mph winds and miles of thick mud at Ashridge made it a very challenging run - going over Ivinghoe Beacon there were moments when I was afraid I would be blown off my feet!". Linda completed the race in 3:12:46. Lindsay Cook added "it was just my kind of run. At least half of it was pretty muddy underfoot, it was fairly hilly and extremely windy". Lindsay crossed the line in 3:40:04. Completing the trio of Squirrel ladies was Miranda Morgan who finished in 3:22:11
David Annetts continued his impressive race-walking form taking part in two races in a fortnight. In the Molly Barnett / England Athletics 10k Race Walk Championship at Warwick University David was happy to finish 8th in a high quality field in a PB of 49:17. On 16th March he travelled to Sussex for the opportunity to get a longer track race. Though it was wet and windy the conditions were less of a hindrance than he had anticipated. To cap it all, David said "I kept my concentration to continue to the finish knowing that I'd been given the bell a lap early!" David won the race in another PB of 48:29.3
Saturday saw the club run of the month at Letchworth parkrun. Battling 45 mph and 'carnage corner' the following club members battled Strom Hannah to record finish times: Peter Clarke (22:38), Richard Harbon (22:55), Phil Hunt (23:52), Pete Sibbett (25:12), Ian Datlen (25:31), James Walsh, Mat Ankers (27:20), Angeliki Shearstone (27:49), Jegan Simon (28:16), Lucy O'Connor (31:31), Rhiannon Botha (31:54), Jennie Fraser (31:54), Carl Goodrum (33:01), Andrew Underhill (33:34) and Carol Goodrum (41:05).
In other parkruns, Brian Judkins ran at Cambridge (33:31), Jillian Boys ran at Wimpole (23:56), Chris Poole ran at Jersey Farm (25:07) and 4 squirrels made the short trip to Stevenage. Ellie Scott was first home for the club (23:15) followed by Naomi Parkinson (24:42), Jane Clarke (29:51) and Pat Norris (34:56).


text:
You are here: Home United States New Jersey NJ ARLINGTON: Bergen County
ARLINGTON: Bergen County
West Arlington Jewish Cemetery: North Arlington 07032 (Bergen County). Source: Susan This e-mail address is being protected from spambots. You need JavaScript enabled to view it .Belleville Turnpike, 201-373-0144. Contact: Sanford B. Epstein, Inc., 308 Grove St., Newark, NJ 07103.
Congregation Beth Jacob (Union City, N.J.) and Rochelle Park, Bergen County. Records, 1911-1984. Description: ca. 2.6 cubic ft. (9 boxes, 1 oversize folder). Notes: Orthodox Jewish congregation organized in West Hoboken (now part of Union City), Hudson County, New Jersey, in 1906 and incorporated the following year; bought the former First Presbyterian Church building in 1907 and subsequently converted it into a synagogue; purchased tracts in the West Arlington Cemetery in North Arlington, Bergen County, New Jersey (in 1918) and in Riverside Cemetery in Rochelle Park, Bergen County (in 1923), for resale to congregation members as burial plots; �organization begun about 1920,�; disbanded in 1986. �two deeds, 1933, �cemetery files, 1921-1970; Yizkor scroll memorial files, 1967-1970 � The cemetery files include deeds, 1918-1961, annotated maps of the Congregation's property at West Arlington Cemetery (undated) and at Riverside Cemetery (1922), a rendering of a cemetery gate, 1954, for Riverside Cemetery, requests for permits to erect monuments, 1961-1970, a record of (burial?) permits issued, 1967-1969, and miscellaneous other records, in part relating to cemetery maintenance. A few of the later items in the file pertain to land in the Arlington Jewish Cemetery in North Arlington. Acquired 1986. Finding aid available in the repository. Location: Congregation Beth Jacob, Union City, N.J. Records. MC 963. Special Collections and University Archives, Rutgers University Libraries. Control No.: NJRV94-A16


text:
Latin Locals is a production and services company that designs, sources and delivers Production solutions in Latin America, for the media, audiovisual and entertainment industries.
Latin Locals' team of seasoned industry professionals and network of production companies, bring you the knowledge, experience, contacts and market intelligence - to make things 'happen' for your project in Latin America.
Including professional talent, experienced crew, skilled technicians, specialists and top local suppliers, plus access to some of the best locations Latin America has to offer.
HIGH LEVEL PROFESSIONAL PRODUCTION AND PROJECT EXECUTION.
Whether it's in Mexico City, Buenos Aires or Havana... The Caribbean, a jungle of Costa Rica, the Atacama Desert or the Andes – if you need solutions in Latin America - LATIN LOCALS can put it together.
Delivering results for our clients.
View a list of most of the services offered by LATIN LOCALS here.
LATIN LOCALS' TEAM IN CUBA RECENTLY MADE HISTORY BY PRODUCING THE FIRST US TV COMMERCIALS SHOT IN CUBA IN OVER 50 YEARS!
Client: Western Union
Agency: McGarryBowen / Bromley
info@latinlocals.net
view Latin Locals locations on:
LATIN LOCALS NETWORK IS A PRODUCTION AND SERVICES COMPANY.
IT'S A FACILITATION ORGANISATION.
QUITE SIMPLY, IF YOU NEED SOLUTIONS IN LATIN AMERICA; LATIN LOCALS CAN HELP.
Helmed by renowned Mexican filmmaker Gabriel Beristain and Australian Producer Sacha Rodriguez, Latin Locals can help you with everything from traditional procurement and negotiation to the complete design, sourcing and delivery of various types of productions and solutions, from simple to complex.
We can produce anything from your next Feature Film in Mexico, a Television Commercial in Havana or the Cuban Caribbean, to a Large Live Concert in an epic or historic location.
We can also do simpler (but just as important) assignments for your production - maybe just a 'location scout'? or perhaps a 'photo shoot' (for your new brand) in a magical old Hacienda...
Latin Locals also carries out custom research and market intelligence projects for organisations looking at doing business with Latin American partners in various industries.
TRAILBLAZING SOLUTIONS FOR NEW ENDEAVOURS IN PRESENT AND FUTURE LANDSCAPES.
MEDIA & CONTENT PRODUCTION
Branded Content & Design
Photographic Shoots
(fashion, corporate +)
SPECIAL EVENT PRODUCTION
On location Events
Fairs / Exhibitions
Custom Branded Events
BUSINESS ASSIGNMENTS
NEW ENDEAVOURS
Trail Blazing - we love it!.
INCORPORATING
Project Design and Presentation
Shooting Schedules and Script Breakdowns
Budgeting and Accounting
Casting, Cast & Crew
Production Design, Art Dept. & Set Construction
Location Management & Permits
Unit Management & Catering
Production Vehicles & Picture Cars (inc Vintage)
Trained Animals
Travel, Logistics & Security
Customs and Work Visa Permits
Post Production of Image and Sound
AMONG various services and solutions at hand...
LATIN LOCALS IN CUBA - MAKING HISTORY WITH TOP LEVEL MEDIA PRODUCTION
We've recently produced the first US TV commercial to be shot on the island in over 50 years, among various exciting new projects in the works and on the way to Cuba.
More international productions are arriving to shoot in Cuban territory, as part of an increasing recent trend; lured by the beauty of the city of Havana, the charm of its streets and edifices, its light, its people, its ethnic diversity, its myriad of different scenes and locations within the island, along with a high level of artistry of its Cuban filmmakers and technicians...
VEDADO FILMS - OUR TEAM IN HAVANA - is the best choice for your upcoming production in Cuba. It is so much more than an integrated audiovisual production company in Havana; it is the answerto a new generation of Cuban filmmakers, able to produce movies, advertising and television of the highest quality.
OUR SPECIALTY is to understand the needs of every one of our clients and offer tailor-made creative solutions, so that the experience of shooting in Cuba is not only successful but also unique.
"Filming in Cuba has its secrets, however, and our team know all of them. We are the ideal conduit to produce your best audiovisual content in Cuba and to make the most of what Cuba has to offer to the motion picture and advertising world"
– Gabriel Beristain, Director of Latin Locals.
THE EMPIRE OF HAVANA - A NEW FEATURE FILM TO BE DIRECTED BY GABRIEL BERISTAIN
It's the late fifties and Havana is filled with glamour and excitement. It's a world built by the mob, teetering on the edge. Will the smartest man in the underworld be able to consolidate the empire in time, before the revolutionary winds of change transform the island forever?
THE EMPIRE OF HAVANA, to be shot on location in the legendary architecture of the era, is a portrait of the last days of the U.S. mob in Dictator Batista's Cuba, as seen through the eyes of a young croupier who was the personal driver of Meyer Lansky, the architect of the mafia's overseas empire. By 1957, the 'financier of the mob', Meyer Lansky had already built enough hotels and casinos in Havana to produce and house the criminal proceeds of the U.S. mafia.
RON PERLMAN & THE HAVANA HARLISTAS
Cuban Harley riders - otherwise known as 'Harlistas' - have formed a distinct subculture that spans back more than half a century. Keeping these classic American bikes running during the embargo has taken extreme ingenuity and shown a love for a Classic American Icon. Ron Perlman, one of Hollywood's most recognisable actors, was in Havana last month to shoot a trailer for the new series with the team in Cuba. Stay tuned for news of season one!
LATIN LOCALS TO PRODUCE CONTENT AND MEDIA PROJECTS INVOLVING AUSTRALIA AND LATIN AMERICA
• Projects involving Mexico and Cuba will include feature films and documentaries
• Unsolicited submissions will be accepted in the form of a 'one page pitch document' (225 words) - sent to: info@latinlocals.com
LATIN LOCALS TO OFFER SPECIAL ASSIGNMENT SERVICES IN MEXICO*
Our team in Mexico is putting together custom procurement and in Market B2B assignments for Australasian businesses looking for opportunities in Technology, Retail Tourism and Manufacturing among other industries.
*Yes! - We do remain a production and services company delivering the highest quality production solutions for the media, audiovisual and entertainment industries in Mexico.
LATIN LOCALS LOCATIONS INCLUDE:
CUBA BARACOA COJIMAR CIENFUEGOS HAVANA TRINIDAD VARADERO MEXICO ACAPULCO AGUASCALIENTES BAJA CALIFORNIA CANCUN COPPER CANYON HUATULCO LORETO MAZATLAN MERIDA MEXICO CITY MULEGE OAXACA REAL DE CATORCE SAN JOSE DEL CABO ZACATECAS...
WE CAN ALSO COVER MOST OF LATIN AMERICA FROM ARGENTINA THE CARIBBEAN AND CHILE TO URUGUAY. JUST ASK US HOW.


text:
package com.asakusafw.dag.compiler.internalio;

import static com.asakusafw.dag.compiler.codegen.AsmUtil.*;

import java.util.Collection;
import java.util.Set;

import org.objectweb.asm.ClassWriter;
import org.objectweb.asm.Opcodes;
import org.objectweb.asm.Type;

import com.asakusafw.dag.compiler.codegen.ClassGeneratorContext;
import com.asakusafw.dag.compiler.model.ClassData;
import com.asakusafw.dag.runtime.internalio.InternalInputAdapter;
import com.asakusafw.lang.compiler.model.description.ClassDescription;
import com.asakusafw.lang.compiler.model.description.TypeDescription;
import com.asakusafw.lang.utils.common.Arguments;

/**
 * Generates {@link InternalInputAdapter}.
 * @since 0.4.0
 */
public class InternalInputAdapterGenerator {

    /**
     * Generates {@link InternalInputAdapter} class.
     * @param context the current context
     * @param spec the target input spec
     * @param target the target class
     * @return the generated class data
     */
    public ClassData generate(ClassGeneratorContext context, Spec spec, ClassDescription target) {
        ClassWriter writer = newWriter(target, InternalInputAdapter.class);
        defineAdapterConstructor(writer, InternalInputAdapter.class, v -> {
            v.visitVarInsn(Opcodes.ALOAD, 0);
            getConst(v, spec.id);
            getArray(v, spec.paths.stream().toArray(String[]::new));
            getConst(v, spec.dataType);
            v.visitMethodInsn(
                    Opcodes.INVOKEVIRTUAL,
                    target.getInternalName(), "bind", //$NON-NLS-1$
                    Type.getMethodDescriptor(typeOf(InternalInputAdapter.class),
                            typeOf(String.class), typeOf(String[].class), typeOf(Class.class)),
                    false);
            v.visitInsn(Opcodes.POP);
        });
        return new ClassData(target, writer::toByteArray);
    }

    /**
     * Represents an input spec for internal I/O.
     * @since 0.4.0
     */
    public static class Spec {

        final String id;

        final Set<String> paths;

        final TypeDescription dataType;

        /**
         * Creates a new instance.
         * @param id the input ID
         * @param paths the input paths
         * @param dataType the input data type
         */
        public Spec(String id, Collection<String> paths, TypeDescription dataType) {
            Arguments.requireNonNull(id);
            Arguments.requireNonNull(paths);
            Arguments.requireNonNull(dataType);
            this.id = id;
            this.paths = Arguments.freezeToSet(paths);
            this.dataType = dataType;
        }
    }
}

redpajama_set_name: RedPajamaGithub


text:
Q: SQL in clause, on column, doesn't work properly I have a table named 'product' which has a column named 'id_subcategory'.
This column contains list of numbers separated by comma.
The problem is this query find the 91 number only if it's the first in list. Otherwise returns 0. And it is not ok.
SELECT COUNT(*) FROM product WHERE 91 IN (id_subcategory);

What should I do?

A: You probably want WHERE ',' || id_subcategory || ',' LIKE '%,91,%'
This isn't going to use indexes because of the leading %, so you should consider not storing comma separated lists if you will need to query the subcategories often.

redpajama_set_name: RedPajamaStackExchange


text:
Q: Close bootstrap modal after Ajax call I want to close bootstrap-modal after Ajax call. For, this purpose I call $(myid).modal('close'). This event is called, but not in a proper way. Likewise, the modal box is gone but an overlay of grey color doesn't fade out some reason. Below I put my some stuff for lookup and help me.
Thanks a lot.
If I write my last two lines above ajax_dashboard_listing() function then hide properly
$('body').on('click', '.ajx', function() {
        $id = $(this).data('target');
        salesRepId = $(this).data('id');

        var data = {
            "target_id": $(this).data('target'),
            "target":  $('#target_'+$id).val(),
        }

        ajax_dashboard_listing(data);

        $('#exampleModalCenter_'+$id).modal('hide');
        return;
    });

A: $('#modal').modal('toggle');
Try this one. Its works for me.

A: Add class close-btn to your dismiss button modal and try this :
$('.close-btn').click()


text:
Germany supports Ghana to become vaccine manufacturing hub- Ambassador
Date: Feb - 16 - 2022 , 07:59
BY: Juliet Akyaa Safo
Mr Daniel Krull (arrowed), Ambassador of the Federal Republic of Germany to Ghana, speaking to the press. Picture: ELVIS NII NOI DOWUONA
Germany has expressed its commitment to support Ghana's effort to become a pan-African vaccine manufacturing hub.
Already, the German Development Cooperation and the European Union (EU) - Team Europe have initiated measures to ensure that Ghana's domestic vaccine production is realised.
The partnership forms part of a 10-year Ghana vaccine manufacturing road map to make the country a vaccine manufacturing centre in the sub-region.
"The initiative will help create an enabling environment for local vaccine manufacturing in Africa and tackle barriers and demand siders. It is being backed by €1 billion from the EU budget and European development finance institutions such as the European Investment Bank (EIB)," the German Ambassador to Ghana, Mr Daniel Krull, said.
He said the project was for a period of 27 months — from April 2022 to June 2024 — with total funding support of over €2.8 million.
"This is co-funded by the EU and the German Federal Ministry for Economic Cooperation and Development (BMZ). "The government of Ghana has already committed US$25 million seed money to the overall vaccine manufacture initiative and this project forms an integral part of the overall road map," he added.
Mr Krull, who was speaking at a press briefing at his residence in Accra yesterday, further said the collaboration would also facilitate the upgrading and strengthening of the Food and Drugs Authority (FDA).
He explained that the support for the FDA was contained in the framework of the Team Europe initiative on manufacturing and access to vaccines, medicines and health technology (MAV+) in Africa.
Committee in Germany
The Ambassador said representatives of the Presidential Vaccine Manufacturing Committee were currently in Germany to meet stakeholders, adding that "two weeks of meetings, inspection of research facilities and vaccine production sites lies ahead".
President Nana Addo Dankwa Akufo-Addo is also expected to arrive in Germany today to witness the presentation of a BioNtech modular production facility for MRNA vaccines.
Germany-Ghana cooperation
Mr Krull said that in spite of the COVID-19 pandemic, trade figures between Germany and Ghana remained relatively stable, and that Germany would remain a major bilateral provider of development cooperation funds for Ghana.
"The current projects portfolio amounts to over €700 million, focusing on green energy, inclusive growth and good governance," he said.
He added that economic ties between the two countries had "a long history and a bright future, particularly with the operationalisation of the African Continental Free Trade Area (AfCFTA)".


text:
Tabia kan syfta på följande platser:

Filippinerna

 Tabio (ort i Filippinerna), Kordiljärernas administrativa region, Province of Benguet,
 Tabid, ort, Norra Mindanao, Province of Misamis Occidental,

Marocko

 Tabia (kommun i Marocko, Souss-Massa-Draâ), Taroudannt,
 Tabia (kommun i Marocko, Tadla-Azilal), Azilal Province,

Robotskapade Filippinernaförgreningar
Robotskapade Marockoförgreningar


Rita Fuerst Adams transforms charitable and philanthropic organizations at the heart social change into professionally run, better funded, effective organizations.
Key to building successful organizations is establishing a strategy for growth, developing the total necessary financing, and creating and executing on a persuasive messaging campaign to communicate the organization's impact and goals.
For more than three decades, and throughout the U.S., Rita has served charitable and philanthropic organizations with operating budgets of $1 million to $1.5 billion and resulting campaigns ranging from $1 million to $450 million. Her experience includes working with causes in education, youth, the arts, community and economic development, historic preservation, health care, international relations, and professional and civic affairs.
Rita taught Entrepreneurship for Nonprofits for the masters in Organizational Leadership at Wheelock College. She has written and published extensively in the field, including editing the book for the Center on Philanthropy, What Fundraisers Need to Know About State and Federal Regulation: How it Can Influence All Aspects of Their Work.


HANOI (Reuters) - Police in Vietnam's Ho Chi Minh City on Friday issued a prosecution order for an American man of Vietnamese descent for his alleged involvement in a protest over government plans for economic zones last week, state media reported.
William Anh Nguyen, born in 1985, was one of thousands of people who protested on Sunday against a draft law to develop economic zones under which land leases of up to 99 years will be offered to investors.
Protesters fear the leases may be snapped up by investors from powerful neighbor China, with which Vietnam has a rocky history.
A U.S. State Department official said the State Department has raised concerns and engaged with Vietnamese authorities on the matter and that the Vietnamese government permitted consular access to Nguyen on Friday.
Video footage of Nguyen shared on social media showed he had blood on his head during the protest. Vietnam's Foreign Ministry spokeswoman Le Thi Thu Hang denied any use of force against Nguyen during a news conference on Thursday.
They said initial investigations showed there were signs of political opponents and reactionary groups having incited people to protest and destabilize the security and political situation.
The protests have come at a time of rising tensions over the disputed South China Sea, nearly all of which is claimed by China.
Vietnam is one of several countries in the region that have claims in the South China Sea, through which an estimated $5 trillion in trade passes each year.


text:
Your Next Colonoscopy Could Get an Assist From AI
Nov. 11, 2022 – Artificial intelligence holds a lot of potential in medicine, helping doctors find skin cancer, flagging potential issues on a chest X-ray, and assisting in many other procedures. Screening for colorectal cancer during a colonoscopy is another prime example.
A colonoscopy — recommended for Americans at average cancer risk starting at age 45 — won't be much different for patients with the addition of artificial intelligence, or AI. But behind the scenes, AI could be making detection of any precancerous polyps or cancerous lesions more likely.
"AI-enhanced colonoscopy effectively turbocharges the physician's ability to find even the most subtle precancerous polyps," says Tyler M. Berzin, MD, a gastroenterologist at the Center for Advanced Endoscopy at Beth Israel Deaconess Medical Center in Boston.
The technology is designed to flag anything the computer "sees" as suspicious, but it does not replace the training and expertise of a gastroenterologist. Even with AI, doctors remain at the patient's side and perform the procedure.
The doctor remains in full control, says Prateek Sharma, MD, a gastroenterologist and professor of medicine at University of Kansas School of Medicine in Kansas City, KS. "AI is assisting and alerting them to colon polyps — the precancerous lesions in the colon — so that the doctor can remove them."
Controversy Continues
Size, height, and numbers matter with polyps. Doctors generally remove or biopsy lesions 10 millimeters and larger.
But there remains less consensus about the best approach to smaller polyps.
"The clinical relevance of detecting and removing small (5 to 9 mm) or diminutive (less than 5 mm) adenomas is a subject of ongoing debate," Berzin and co-authors wrote in a leading gastroenterology journal in May 2020.
One of the potential disadvantages to using AI polyp tools, for example, is "the risk of removing a higher number of diminutive or hyperplastic polyps, which increases cost and risk, without any benefit to the patient," Berzin says.
"Trained gastroenterologists are experts at identifying and removing precancerous colon polyps," Berzin says. "But a gastroenterologist working with an AI polyp detection tool has a big advantage because AI computer vision tools can simultaneously analyze every pixel of the endoscopy monitor and can do so without being distracted or fatigued for even a millisecond."
The benefit for patients is "another pair of eyes looking for polyps and helping the doctor," says Sharma, who is also chair of the Artificial Intelligence Task Force at the American Society for Gastrointestinal Endoscopy.
AI is based on computer instructions called algorithms that learn the difference between worrisome and benign colonoscopy images and videos. AI gets better over item in a process called machine learning. When an AI system spots a potential area of concern, the technology calls attention to it by framing it within a box on the screen. Some systems also sound an audible alarm.
"We are seeing more interest in using these algorithms since they will standardize endoscopists' polyp detection and, therefore, reduce the number of colon cancers missed," says Sravanthi Parasa, MD, a gastroenterologist at the Swedish Health Services in Seattle.
"These products are slowly gaining traction. During colonoscopy scheduling, patients should ask if their endoscopist has access to augmented diagnostic tools," she says.
The technology is not accurate 100% of the time – there can be false positives where the system flags a bubble in the colon, for example, as potentially dangerous. That's just one reason that doctors still have the final say on whether a polyp is suspicious or not.
AI or no AI, "colonoscopy has long been our most effective tool for preventing colon cancer, detecting precancerous polyps earlier than any other screening method," says Berzin, who is also an associate professor of medicine at Harvard Medical School.
AI Can Be Costly
AI and machine learning already play a role in "smart" technologies (smartphones, smartwatches, and smart speakers), self-driving cars, and speech recognition software. But the use of AI in medicine is comparatively new. And like a lot of novel technologies, it's also expensive. "The AI equipment needs to be purchased and is expensive," Sharma says.
"The cost of the algorithms currently can be prohibitive for some centers in the current health care landscape," Parasa agrees. "The cost is likely to come down as more algorithms enter the GI market, as it is with other software solutions."
Colorectal Cancer Is Common
Not counting some kinds of skin cancer, colorectal cancer is the fourth most common cancer in Americans. It is also the fourth leading cause of cancer-related deaths in the United States, the CDC reports. More than 150,000 Americans will be diagnosed with colorectal cancer and more than 50,000 will die in 2022, according to National Cancer Institute figures.
Future Insights
More research is needed to examine how humans and this technology interact, Berzin says. "The most interesting research in this space will not be about comparing 'physician versus AI,' but will be focused on understanding the nuances of 'physician plus AI.'"
In the U.S., there are at least three FDA-approved AI algorithms for polyp detection, and more are being developed, Parasa says.
"In addition, other applications which are currently available on the European market might be available in the U.S. market in the near future, including polyp characterization."
"As the field matures, we will likely see more AI augmentation tools that will assist us in detecting and diagnosing GI conditions in real time," she adds. "A suite of algorithms like this will definitely improve patient care and outcomes."
Even though AI is somewhat of a work in progress in medicine, Berzin expects the combination of doctor and AI technology "will translate into the highest possible protection from colon cancer in the long term."
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text:
package tests;

import catg.CATG;
import database.table.SymbolicTable;
import database.table.commands.SelectCommand;
import database.table.from.From;
import database.table.groupby.DefaultGroupBy;
import database.table.having.HavingTrue;
import database.table.internals.ForeignKey;
import database.table.internals.Row;
import database.table.internals.Table;
import database.table.internals.TableFactory;
import database.table.operations.IdentityOperation;
import database.table.operations.Operations;
import database.table.select.Select;
import database.table.where.Where;

public class ManyColumnsOrRecords {
	public static int l_c1;
	public static final int RECORD_COUNT = 5;
	public static final int COLUMN_COUNT = 20;

	public  static void testme(Table customers, int c1){
		l_c1 = c1;

		Table t = (new SelectCommand(
                new Select() {
                    public String[] selectAs() {
                        return new String[]{"Id"};
                    }

                    public Operations[] select() {
                        return new Operations[]{new IdentityOperation("Id")};
                    }
                },
                new From(new Table[]{customers}),
                new Where() {
                    @Override
                    public boolean where(Row[] rows) {
                    	for(int i = 1;i < COLUMN_COUNT; i++){
        					Integer c = (Integer) rows[0].get("C"+i);
        					if (c == null || c != l_c1) {
                                CATG.assertIfPossible(1,false);
        						return false;
                            }
        				}
                        CATG.assertIfPossible(1,true);
        				return true;
                    }

                },
                new DefaultGroupBy(),
                new HavingTrue(),
                null, false
        )).execute();

		System.out.println("c1="+c1);
		System.out.println(t.size() + " records are selected.");
		if(t.size() >= RECORD_COUNT){
			System.out.println("reach goal!!");
		}
		else{
			System.out.println("not reach goal...");
		}
    }

    public static void main(String[] args){
    	int c1= CATG.readInt(20);

    	String[] names = new String[COLUMN_COUNT];
    	int[] types = new int[COLUMN_COUNT];
    	int[] constraints = new int[COLUMN_COUNT];
    	ForeignKey[] foreignKeys = new ForeignKey[COLUMN_COUNT];

    	names[0]="Id";
    	types[0] = Table.INT;
    	constraints[0] = Table.PRIMARY;
    	foreignKeys[0] = null;

    	for(int i=1;i<COLUMN_COUNT;i++){
    		names[i] = "C"+ i;
        	types[i] = Table.INT;
        	constraints[i] = Table.NONE;
        	foreignKeys[i] = null;
    	}

        Table customers = TableFactory.create("Customers",
        		names,
        		types,
        		constraints,
        		foreignKeys
        		);

        SymbolicTable.insertSymbolicRows(customers, RECORD_COUNT);

        testme(customers, c1);
    }
}


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text:
Incidents in the Life of a Slave Girl by Harriet Ann Jacobs
1671 WordsJan 31, 20187 Pages
As a female African American slave, Jacobs had no voice in telling the empty audience of followers the truth about the horrors slavery has instilled upon her and countless others of her kind. This is why I believe Jacobs uses a second persona in aiding her to retell her stories, which is an attempt to draw remorse and sympathy from her readers, as well as a way to unravel the truth behind slavery to those that overlook and accept it in society. In Jacobs' Incidents in the life of a slave girl, Jacobs uses the maternal character and narrative aspect of a fictional slave girl to highlight, through the many angles, the effects of slavery on African American individuals, families, and lives. By doing so, she hopes to motivate, inform, and engage others to strive for change by telling her personal life experiences through a fictional character so that slavery can be addressed as the root of all problems, first hand. Before analyzing the narrative, I would like to address Jacobs' choice in writing a fictional narrative instead of a personal narrative told in first person. I believe this decision also contributes to the craft that Jacobs writes with in that the fictional narrative allows for a window of reaching out to the reader, while the personal narrative approaches the reader directly. By using a fictional narrative, Jacobs is able to form a connection and bond between her character and her reader by having a beginning, middle, and an end to her novel. This medium allows for
Harriet Jacobs' Fight Against Intolerance
determined will. There is might in each" a statement from Harriet Ann Jacobs reflecting her will to overcome the standards of society (97). Harriet Jacobs' life revolved around slavery from birth to death. Jacobs was a mother of two with determination and insight to make choices to change the way of life for her children. Harriet Jacobs was the first African American women to have her slave narrative published retelling her life story exposing the years she spent escaping slavery and the
Incidents In The Life Of A Slave Girl Essay
Harriet Jacobs wanted to tell her story, but knew she lacked the skills to write the story herself. She had learned to read while young and enslaved, but, at the time of her escape to the North in 1842, she was not a proficient writer. She worked at it, though, in part by writing letters that were published by the New York Tribune, and with the help of her friend, Amy Post. Her writing skills improved, and by 1858, she had finished the manuscript of her book, Incidents in the Life of a Slave Girl
Incidents in the Life of a Slave Girl The story I will be discussing is entitled Incidents in the Life of a Slave Girl by Harriet Ann Jacobs. This book is relative to more than a few of previous topics that have been discussed in class during lectures. The book touches on the struggles that enslaved women faced on a day to day basis. It follows the life on author Harriet Ann Jacobs and does an excellent job demonstrating how women in bondage unlike their free white counterparts, had no male figure
Incidents In The Life Of A Slave Girl Analysis
of Slavery Incidents in the Life of a Slave Girl, a slave narrative written by Harriet Ann Jacobs is highly commended for the portrayal of women during the excruciating times of slavery. Disregarding that the slave narrative was initially written for the audience of Caucasian women, "…, as white women constituted Jacobs's primary audience at the time she wrote her narrative" (Larson,742) the struggles of being a female slave were emphasized throughout the narrative. Harriet Ann Jacobs elaborates
Gender Specific Slavery During The Period Of The Civil War
property as opposed to an actual human being, some slaves managed to rebel and write down their account of white slave owners' dehumanization of black slaves. In social reformer and writer Frederick Douglass' Narrative of the Life of Frederick Douglass an American Slave he writes of rebelling against his physically abusive owners and triumphantly gaining freedom. In writer Harriet Ann Jacobs narrative Incidents in the Life of a Slave Girl, Jacobs writes of rebelling against her sexually abusive owner
Essay on Out of the Silence
The slave narrative genre is an important part of American history. These stories are not only portraits of individual history, but also of American history. By reading the stories of the past we can better determine the path of the future. The personal stories of Frederick Douglass and Harriet Jacobs are two excellent examples of the slave narrative genre in American literature. To be sure, bondage and oppression had a lasting and profound effect on both genders; however, men and women experienced
The Life Of A Slave By Harriet Jacob Essay
people were treated so badly and it was "normal," it was acceptable. These slaves lived and worked in very harsh conditions. I believe the only reason why we know so much about how bad slaves were treated is because of three autobiographies, Incidents in the Life of a Slave by Harriet Jacob, Autobiography of Frederick Douglass by Frederick Douglass, who had a huge impact during the times of slavery, and Twelve Years a Slave by Solomon Northup. Because of these three autobiographies historians can
The Life Of Frederick Douglass And Harriet Ann Jacobs
Frederick Douglass and Harriet Ann Jacobs There are those in America who believe that it is time we move past the deep complex feelings towards the cultural repercussions of slavery. Much like the modern-day, Germans feel in their association with the murders and tragedies after World War II, many Americans – especially white American – want to feel an understandable disassociation from the white Americans who propagated slavery. Thus calling this unbearable reminder of the past "white guilt"
Comparing Narrative of the Life of Frederick Douglass, an American Slave and Incidents in the Life
Comparing Narrative of the Life of Frederick Douglass, an American Slave and Incidents in the Life of a Slave Girl What provokes a person to write about his or her life? What motivates us to read it? Moreover, do men and women tell their life story in the same way? The answers may vary depending on the person who answers the questions. However, one may suggest a reader elects to read an autobiography because there is an interest. This interest allows the reader to draw from the narrator's
The Humiliating Nature of Enslavement, Sexual Savage Exploitation, and Degradation in Autobiographical Narratives of Frederick Douglass and Harriet Ann Jacobs
savage exploitation, and degradation in autobiographical narratives of Frederick Douglass and Harriet Ann Jacobs In the age of Romanticism, slavery and the slave trade provoked sharp criticism and controversy and played a very significant role in shaping public opinion and causing moral opposition to injustice and tyranny. Since Columbus's journey opened the doors of the Atlantic passage to African Slave Trade, slavery became man's greatest inhumanity to man "converting" the victims into labor
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Research on the Logistics and Mechanisms of Attention


One of the most common questions we get currently is 'Will you have enough copies to ship to everyone'.
That's an interesting question because our best answer is usually 'Probably'.
See, here's how pre-orders work. We often get an e-mail from our distributor(s) anywhere from a week to a month before they need to place their pre-order with their publisher. At that time, we guess at the quantity we need. Often this is before we have the game on the site.
In the interim period, if we have time; we get the game up on the site and hopefully receive a few pre-orders. If we have time, we update the distributor on the new quantity.
The distributor then inform the publisher of the quantity he requires with an added amount for over-stock and last minute orders.
When the publisher finally receives their orders and games, they must then decide how to ship their orders out. In most cases, they have more than sufficient games on-hand to fulfill all orders.
The tricky part is when the total number of orders the publisher receives is greater than their total number of copies printed. They must then decide how to allocate their orders. At this point, I'm not going to speculate on how they do so – I'm not a publisher and I'm sure there are as many 'fair' methods as there are publishers.
What it does mean is that they ship fewer quantities (e.g. 80 copies instead of a 100) to the distributor.
The distributor, who now has 20 fewer copies than they ordered must decide how to allocate their orders. Again, how allocation happens is a blackbox for the most part. If they are lucky, they might only have 70 orders from retailers (i.e. the other 30 were meant to be held in their warehouse for over orders). Often, they 80 – 90 copies ordered.
In the meantime, our pre-order numbers start creeping up for the hot game. This might be because buzz has continued to grow. It often happens when a game has finally been announced to have reached the publisher. Suddenly, our pre-orders go from 2 copies to 6 copies, at the same time we might get allocated from our order of say 10 copies down.
And that's where the entire question becomes interesting. The quantities and likelihood of this happening for us often occurs when the game is truly hot – so our pre-order with our distributor is often double to triple our (at that time) pre-order. So, we might ask them for 10 copies because we say a total of 5 pre-orders. Not a bad number, it gives us at least 5 more copies with an expected 2 to 3 more pre-orders at the last minute. However, if we get allocated; then the last customer might not get it.
This is why we say 'probably'. Allocations happen at both the publisher and distributor level and there's just no way for us to tell how many copies will finally arrive with us for a truly hot game. More often than not, it's sufficient but on occasions for a truly hot game – it's just not.
Pre-order early. I know I've said it before, and I'll say it again. Remember, we don't charge pre-orders immediately anyway, and it puts you in-line immediately. It helps us, it helps the distributor and eventually it helps the publisher.
For those interested, I know for a fact that one of my distributors does percentage-based allocation of product which for some reason is delivered in less than ordered quantities from the publisher. This is done down to a minimum.
Say you have a case on order, and three other retailers have four cases on order, for a total of 13.
The distributor receives 8, and would give 2 cases to each of the retailers having 4 on order, and 1 case to the retailer with 1 case on order (last case would probably be divided up, or possibly given to the largest customer). I think this is a fair allocation.
Oftentimes I will be in direct communication with the distributor. So if he has limited stock, and I have more than what I preordered, I will be "polite" and tell him to go ahead and ship me only what I have preorders for, and he in turn can satisfy other customers who may need the stock more than I do.
This makes for a very nice working relationship, where when I say I NEED X number of copies, he will do his best to allocate to me what I need, knowing I have preorders, and am not looking to stock up on a high-request item.


The IOFTC is pleased to announce that our 12th Competition will return to Nepal, and we are permitted and supported by the Nepal National Sports Council. We will be hosted in the city of Itahari, and we'll be competing in the brand-new stadium.
NOTE: When you register, IOFTC will send an event Registration Confirmation email to the email you provide in your registration. This email will include all your personal event registration information. PLEASE USE THIS EMAIL: For YOUR OFFICIAL INVITATION TO THE 12th IOFTC IN NEPAL. For Check-In on December 31st. Also bring your payment, with you at that time.
International: $75 USD (Special Benefit for International - 3 days of food and lodging are included. See the registration page for details).


Showing results by author "Paloma Sánchez"
Carlota Molina has a brilliant career as a judge in Madrid, the respect of her peers, and an independent life. But it's a life still haunted by the specter of a father she's been estranged from for decades. Then one day Carlota gets a phone call from a familial stranger - her half sister, Julia - with an impassioned request. After years of pain and distance, Carlota's father, Clemente, wants to see her before he dies...and to settle the past. Seizing on the opportunity to confront all her disillusions, Carlota begins to unravel the lies and deception in her family history.


text:
6B CREATES INNOVATIVE DIGIHEALTH APPLICATION TO SOLVE GLOBAL DATA PROBLEM
6B, the Yorkshire based development agency, has worked on Archer, a complex Software-as-a-Service (SaaS) project for IgniteData, the organisation that is shaping the future of clinical data, to create one of the UK's first innovative DigiHealth Applications.
Backed by UK Government funding (Innovate UK), using state of the art technology to allow direct Electronic Health Record (EHR) to Electronic Data Capture (EDC) transfer, cloud-based Archer will revolutionise the way that healthcare practices conduct clinical research to solve an ongoing and increasingly expensive global problem.
Developing a mapping engine that is capable of remotely accessing and transforming patient medical records, Archer will enable the automated delivery of accurate, tracked, and validated data to multiple applications.
This means that a process that would otherwise rely on manual data entry across thousands of patient records, will have the potential to deliver efficiencies for clinicians across the NHS and private practices.
As the functionality of the final product would rely on the global standardisation of millions of entries from patient records, 6B used HL7 FHIR, the latest and most widely used standard for healthcare data exchange.
After almost two-years of work for IgniteData and over a year of development from 6B, the final product will take data from healthcare records, and using complex technical coding, standardise the entries before sharing the information in the right format for each EDC.
Jack Mollart, Lead Developer on the project and Back-End Developer for 6B, comments: "When IgniteData approached us about the Archer project, we were immediately struck by the fact this app could change the way that clinicians and healthcare practices approach clinical studies forever.
"This was an intensive and detailed piece of work, but also an exciting brief to take on. Given the complexity and sensitivity of the data, it was essential that the focus on security was front and centre at every stage. There is no margin for error when you work on projects like this.
"Together with IgniteData, we have developed software that will significantly reduce the resource required to process data entry across millions of patient records globally. Rather than relying on manual processing, the Archer app will do much of the work for clinicians, so they can focus on what matters."
Richard Yeatman, Chief Technical Officer at IgniteData, comments: "Up to 70 per cent of the data needed for clinical studies can be found in patient records, but the process is entirely manual. IgniteData's on a mission to change that, to support NHS efficiencies and increase study delivery speed. We needed a solution that could be integrated into the systems used by each healthcare practice.
"We needed a phased product development that would take each stage and ensure that it was compliant and effective. Not only will Archer change the way that clinicians approach trials but also give them the ability to deliver outcomes quicker and with less reliance on administrative processes.
"Working with 6B has been a real partnership. It's taken a great deal of work, patience, and expert collaboration to get us to this point. Becoming one of the UK's first platforms to solve this problem is a real achievement for everyone involved in the development."
Archer is now undergoing rigorous testing and approval by EHRs that will see it implemented into practice and installed in NHS and private systems. The product will be widely available in quarter one of 2021.
With a focus on quality of service and technological innovation, 6B is set on becoming a leading global force in digital delivery.
Continually expanding its client base in breadth and complexity, 6B has worked with several large private-sector clients including Candy Kittens and ITV, as well as ambitious start-ups such as Career Street and Trip Aid.
In addition, it has managed projects for public sector organisations including Public Health England, Bradford District Council, and a number of education and lifestyle bodies. For more information about the agency please visit: https://6bdigital.com/.
Source: Open Communications


text:
Water shortage irks Nimroz farmers
NIMROZ (TOLOnews): A number of farmers in Nimroz said they are faced with the lack of water to irrigation of their lands that ended up to a significant reduction in their products.
Nida Mohammad, a farmer in Nimroz, said the issue has existed for the past two years and has left a negative impact on farmers' lives.
"We farmed our lands and nothing was achieved. There is a severe lack of water. We work hard but the fields are drying up," said Neda Mohammad, a farmer in Nimroz.
"My products were wasted this year due to the lack of water," said Sayed Ahmad, a farmer.
"It has been two years since we lost our products due to lack of water," said Sayed Omar, a farmer.
Analysts said that the lack of water for agricultural lands in Nimroz is the result of poor water management.
"There is no plan for water. We have water resources and we can improve agricultural products if we make a plan for managing water resources," said Mohammad Gul Mohammadi, an analyst.
Meanwhile, officials in Nimroz said efforts are going to address the issue.
"We are trying to address the problem. We have shared it with the Ministry of Agriculture," said Abdul Khaliq Hakimullah, head of the agriculture department in Nimroz.
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Hello again fellow Remodelaholics! It's Dawn visiting again from AD Aesthetic. Today I'm back with another completely free graphic that you can print out and enjoy in your home, featuring an motivational mantra: try and fail, but never fail to try. I always pop in with one or two graphics each month, so if you've missed any or need a place to start when setting up your gallery wall, be sure to visit my page. You'll also find lots of home decor tips and decorating moodboards to inspire you.
Speaking of inspiration, today's print is meant to do just that – inspire you to keep trying. Do you ever get stuck in a creative rut? As a full-time creative person, I find that this happens more often than I'd like to admit. Sometimes, I find myself just sitting and staring at my computer willing myself to come up with ideas. I start browsing pinterest, comparing myself to others, and before I know it, I'm paralyzed with the fear that nothing I create will be good enough.
It's times like these, times when I'm struggling to create anything at all, that I need a reminder like today's printable quote: "try and fail, but never fail to try". I know I'm not the only one out there who let's imposter syndrome get the best of them. I don't know about you, but I plan on pinning this one up on my quark board, the one that sits right next to my computer, so I can remember that it doesn't matter if what I create isn't perfect, at least I tried.
If you've ever found yourself sucked into a similar train of thought, download this print now!
I've got you all set up with three common frame sizes, so all you have to do is download and print. All three sizes are included in the same file, so just select the page that features the size of your choice, print and trim that. Pop it in a frame or pin it to your bulletin board for a daily reminder to keep trying.
We love to see how you use our printables in your own home, so don't forget to snap a pic and share it with us by tagging @remodelaholic and @adaesthetic. If you enjoyed today's printable, be sure to hop on over to my site adaesthetic.com where my blogging partner Ashley and I share all things design and decor related.
Thanks again to Cassity and the entire team here at Remodelaholic for having me back each month.