text:
FIRST PRESBYTERIAN CHURCH UNITED IN CHRIST'S SERVICE
Directions to the First Presbyterian Church Galesville, Wisconsin
If you are coming from La Crosse, Wisconsin: Stay on Highway 53 into Galesville. At the Express Mart Convenience Store turn left (this is West Ridge Avenue). Remain on West Ridge Avenue. The church will be on your left in approximately 6 blocks.
If you are coming from Blair or Ettrick, Wisconsin: Take Highway 53 into Galesville. At the Express Mart Convenience Store turn right (this is West Ridge Avenue). Remain on West Ridge Avenue. The church will be on your left in approximately 6 blocks.
If you are coming from Winona, Minnesota or Centerville, Wisconsin: Stay on Highway 54/93 into the west side of Galesville. At the intersection of Highway 54/93 and County Road K turn left. At the next curve turn right. Proceed by G.E.A. Agricultural Services until the next curve. At that curve turn left. In one block the road will curve once again to the right. Go in that direction. From the curve the church is approximately 6 blocks east on the right side of the street.
If you are coming from Arcadia, Wisconsin: Travel to Centerville, Wisconsin. At this point follow the directions above (coming from Winona, MN and Centerville, WI).
If you are coming from Trempealeau, Wisconsin: Take County Road K to Galesville. At the intersection of Highway 54/93 and County K proceed across the State Highway into Galesville. At that point follow the directions for coming from Winona, MN and Centerville, WI. You can also come down Highway 35 into Centerville. At the intersection of Highway 54/93 and Highway 35 turn right onto Highway 54/93. From there following the directions coming from Winona, MN and Centerville, WI.


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View Month: Nov 2014 | Dec 2014 | [ Jan 2015 ] | Feb 2015 | Mar 2015 | Apr 2015 | May 2015 | Jun 2015 | Jul 2015

redpajama_set_name: RedPajamaCommonCrawl


The Milford Spartans are now 5-0 after a hard fought win, on the road against Pelham. It was an emotional night inside the Snake Pit as Pelham High School honored long time fan Ronald Walsh with a remembrance before tip-off. Walsh cheered on the Pelham basketball program for the past 42 years. He was memorialized with a plaque on his favorite seat inside the gymnasium.
The Pythons got off to a fast start scoring on two of their first three possession and taking a 5-0 lead. Senior Captain Kyle Frank connected from beyond the arch for three, then made a steal at half court and scored off the window. Milford would charge right back. Ryan Banuskevich hit back-to-back three pointers to but the Spartans in front 6-5.
The lead would grow 5 more points. After a pair of free throws from Shane Winnett, Nick Gutterson was left alone in the corner for three and he made it count. 11-5 Milford. Timeout, Pelham.
Frank would inch his team closer with a pull-up three pointer and start a rally. The Pythons closed the first quarter on a 9-3 run. At the end of the first we're all tied 14-14.
Milford surged ahead again to start the second quarter. Banuskevich hit another 3-pointer and Winnett followed with a basket down-low, fighting through traffic for the score. A steal by Banuskevich led to an easy lay-up. Next time down the floor he used an up fake to get his defender off balance and then launched a three. It was a 10-0 run to start the second. 24-14, Milford.
Pelham would battle back with three straight baskets. Joe Pantaleo scored inside, Blake Woekel floated a teardrop shot over his defender and drew contact. He missed the free throw. Later after two offensive rebounds Dylan Andrews scored off glass to cut the deficit to 4 points.
Milford would increase their lead with a free throw from Gutterson and a powerful move in the lane by Evan Ryan. A nice pass from Frank gave Pantaleo a nice shot inside. Jamie Pare scored for Milford after picking up a loose ball. Pantaleo closed the half with his 4th basket of the contest. At halftime Milford: 29, Pelham: 24.
The game tighten immediately im the 3rd quarter when Drew Brown sank a three-pointer to close Pelham to within 2 points. Pare responded with a basket of his own. After a kickball stopped play, Frank found Pantaleo open again inside for a quick 2. Pare again responded, this time from long range. Frank came back with a long 2 pointer 34-31 Milford.
The Spartans started to open their lead up in the latter stages of the 3rd quarter. Milford's three co-captains Banuskevich, Winnett and Gutterson combined for 15 points while their defense allowed only 6. Banuskevich's fast pace seemed to give Pelham trouble. He was able, at times, to navigate their defense easily on the way to a score. At the end of the 3rd Milford: 50, Pelham: 37.
A 21 point 4th quarter for the Pythons made things interesting as they were able to close within 6 points, but they got no closer. Milford made their free throws down the stretch and came out victorious 66-58.
"That's a very good basketball team," Milford head coach Daniel Murray said of Pelham. When the game got tight in the 4th quarter both coach and players urged for calm and to slow the pace of the game. "They said it themselves coming off (the floor). We've got to slow down."
Ryan Banuskevich led Milford with 22 points of the night. Shane Winnett finished with 15 points, going 7/10 at the line. Kyle Frank led all scorers with 25 points in the loss. Joe Pantaleo finished with 16 points.


I threw myself at Orchard for 3 months from August 2010 to November just when version 0.5 had been released. Orchard is based on ASP.NET MVC and at the moment is an open source project financially backed by Microsoft. There are some very clever chaps working on Orchard.
Wow look at this code!
At first I was impressed by the quality of the code and the high level of experience and expertise that has clearly gone into Orchard. They've also used lots of open source libraries which introduced me to lots of new concepts and .NET code I would otherwise have never realised was possible. But in the end I just gave up!
In a nutshell it was too hard to get results with the 0.5 version. They're at version 0.8 now with a 1.0 release coming soon. I gave up at version 0.5 so I can't say anything about 0.8 or 1.0. My head-against-wall moments could easily have been due to a lack of documentation, which is fair enough as Orchard isn't even at version 1 yet! The available docs really helped but after I'd read them 20 times I came to the conclusion that I was stuck.
My personal opinion is that in order to produce a flexible CMS in a pre .NET 4 language the code has to be engineered to the point that there is too steep an entry level for a typical enthusiastic module developer. I base this on having worked with Kooboo and Orchard as well as Drupal and WordPress.
I also have the opinion that new CMS's (not just Orchard) think they can push things off to the community too early.
I have now officially dropped the idea of "creating websites for people". It was just something to fill the time and soak up my flailing eagerness while I found a better idea.


rwethereyet? is about two people who are passionate about what they do. It is about committing to something and seeing it through and it is about marching for causes and home.
For a number of years now Ajamu and Jane, who both live in Brixton, have walked around Brockwell Park planning, sharing, challenging, learning and laughing. Ajamu is a fine art photographer, and co-founder ofrukus! Federation Black LGBT arts charity and Jane is CEO at LGBT charity Kairos in Soho. In December 2011, Ajamu had a great idea. He decided that if he achieved confirmation of his exhibition, Fierce he would walk all the way home to Huddersfield and hand an invitation to his mum personally. Jane said 'we can do that', 240 miles, 19 days, 20 miles a day – it's do-able'. Nobody knows whose fault it really was now, but so an arduous training and planning schedule began.
On 27 August 2012, Ajamu and Jane set off from Black Cultural Archives, Brixton for Huddersfield Art Gallery, walking every three days, resting one, for 19 days, arriving on Saturday 15 September 2012. With a team of friends and supporters, and VW camper, Daisy, they walked a total of around 240 miles, connecting with BME/LGBT groups and sites of heritage along the way.


text:
module Doorkeeper
  module Helpers
    module Controller
      extend ActiveSupport::Concern

      private

      def authenticate_resource_owner!
        current_resource_owner
      end

      def current_resource_owner
        instance_eval(&Doorkeeper.configuration.authenticate_resource_owner)
      end

      def resource_owner_from_credentials
        instance_eval(&Doorkeeper.configuration.resource_owner_from_credentials)
      end

      def authenticate_admin!
        instance_eval(&Doorkeeper.configuration.authenticate_admin)
      end

      def server
        @server ||= Server.new(self)
      end

      def doorkeeper_token
        @token ||= OAuth::Token.authenticate request, *config_methods
      end

      def config_methods
        @methods ||= Doorkeeper.configuration.access_token_methods
      end

      def get_error_response_from_exception(exception)
        error_name = case exception
                     when Errors::InvalidTokenStrategy
                       :unsupported_grant_type
                     when Errors::InvalidAuthorizationStrategy
                       :unsupported_response_type
                     when Errors::MissingRequestStrategy
                       :invalid_request
                     when Errors::InvalidTokenReuse
                       :invalid_request
                     when Errors::InvalidGrantReuse
                       :invalid_grant
                     end

        OAuth::ErrorResponse.new name: error_name, state: params[:state]
      end

      def handle_token_exception(exception)
        error = get_error_response_from_exception exception
        self.headers.merge! error.headers
        self.response_body = error.body.to_json
        self.status        = error.status
      end

      def skip_authorization?
        !!instance_exec([@server.current_resource_owner, @pre_auth.client], &Doorkeeper.configuration.skip_authorization)
      end
    end
  end
end

redpajama_set_name: RedPajamaGithub


Theatre New Zealand provides a national link between people who are interested in theatre.
There are thousands of people working in theatre societies, schools, youth theatres and other organisations throughout Aotearoa-New Zealand. You can become involved with others who share your vision, passion and commitment to theatre.
to promote New Zealand theatre.
to encourage high standards in all aspects of theatre including performance, production, staging, design and writing.
to foster the appreciation and study of theatre.
to act as a national consultative and advisory body in all aspects of theatre.
to conduct or arrange courses, workshops, festivals or competitions on any aspect of theatre.


text:
El parvovirus porcí (Porcine Parvovirus, PPV) és un virus DNA monocatenari, sense envoltura, amb una morfologia icosaèdrica i mida petita (20nm) que afecta a la família dels súids. La seva infecció causa infertilitat, descens proliferatiu, momificació i mort fetal, normalment en absència de signes clínics en la mare. Pot ser associat també a un creixement deficient al període postnatal. La malaltia es desenvolupa principalment quan individus seronegatius són exposats al virus via oronasal a qualsevol moment durant la primera meitat de la gestació (primers 57 dies, tenint en compte que en té una durada mitjana de 114), i posteriorment els fetus queden infectats via transplacentària abans que esdevinguin immunocompetents. El PPV és molt freqüent entre tots els porcs d'arreu del món i és enzoòtic a la majoria de col·lectius estudiats. Les enquestes epidemiològiques de la malaltia indiquen que el PPV és la principal causa infecciosa de mort embrionària i fetal. A més del seu efecte directe quant a la falla reproductiva, el PPV pot potenciar els efectes de la infecció per circovirus porcí de tipus II (PCV2) en el curs clínic de la síndrome d'aprimament multisistèmic postdelletament (PMWS).

Etiologia
El PPV és un virus DNA monocatenari, sense envoltura, de simetria icosaèdrica i amb una mida petita (20nm) que pertany al gènere Parvovirus (llatí parvus = petit) de la família Parvoviridae. Tots els PPV aïllats que han estat comparats han resultat ser antigènicament similars, si bé no idèntics. El PPV també està relacionat antigènicament a diversos membres del gènere. La seva identificació pot ser duta a terme, no obstant, a través de proves serològiques estrictes com ara la neutralització del virus (VN) i la inhibició de l'hemaglutinació (HI).

Propietats biofísiques i bioquímiques
Un virió madur té simetria cúbica, dues o tres proteïnes que formen la càpside, un diàmetre aproximat de 20 nm, 32 capsòmers, sense envoltura ni lípids essencials, i un pes de 5'3 x 10⁶ daltons. El genoma viral és àcid desoxiribonucleic (DNA) monocatenari amb un pes molecular d'1,4 x 10⁶ (representa aproximadament un 25% del pes total del virió). Les densitats de flotació (g/ml en clorur de cesi) dels virions infecciosos complets, virions incomplets "buids", i virions als que se'ls ha extret el DNA són, respectivament, 1'38-1'395, 1'30-1'315 i 1'724.

La infectivitat viral, l'activitat hemaglutinant i l'antigenicitat són especialment resistents a la calor, a un ampli interval de pH i a enzims. El PPV es manté estable a un pH de 3 a 10 durant 1 hora a 37 °C i pot resistir una temperatura de 56 °C durant 2 dies, però és inactivat de forma permanent després d'haver estat exposat a 80 °C durant 5 minuts. El virus causa hemaglutinació en eritròcits d'humans, pollastres i conillets d'Índia. L'antigenicitat sembla romandre a les tres proteïnes de la càpside: VPI (81kDa), VP2 (66kDa) i VP3 (62kDa). El virus es replica en cèl·lules que es troben a punt de dividir-se (macròfags alveolars i limfòcits) i pot ser cultivat 'in vitro' en monocapes cel·lulars de ronyó de porc o en línies cèl·lulars contínues. Els efectes citopàtics com ara les inclusions intracel·lulars i l'arrodoniment cel·lular poden ser transitoris als primers estadis de l'aïllament i les cèl·lules poden ser identificades a través de tècniques d'immunofluorescència, immunoperoxidasa, proves de DNA, PCR, reaccions d'hemadsorció i hemaglutinació i mitjançant ELISA.

Replicació
La replicació del PPV in vitro és citocida i es caracteritza per l'arrodoniment, picnosi i lisi de les cèl·lules. Molts dels fragments cel·lulars acostumen a romandre enganxats, atorgant al cultiu afectat una aparença esparracada. Els canvis citopàtics són extensos quan el virus adaptat al cultiu cel·lular es propaga sota condicions apropiades. L'ús de la microscopia d'immunofluorescència (IF) incrementa en gran manera la probabilitat de detectar cultius mínimament infectats.

Els cultius cel·lulars primaris i secundaris de cèl·lules de ronyó de fetus o neonats porcins són els més utilitzats per a la propagació i titració de PPV, tot i que altres tipus de cultius són també susceptibles. La replicació es veu reforçada per la infecció de cultius mitòticament actius. Moltes de les cèl·lules d'aquests es troben en fase S (la fase de síntesi de DNA) del seu cicle cel·lular, on es troben disponibles les DNA-polimerases necessàries per a la replicació del virus.

L'efecte del sèrum a les cèl·lules té també una especial importància, ja que l'activitat mitòtica afecta la replicació del PPV. A més, seria convenient comprovar que els cultius cel·lulars no estiguin contaminats per PPV, perquè a vegades alguns d'ells són preparats a partir de teixits de fetus o nounats infectats sense tenir-ne coneixement. A més, el PPV pot ser introduït de forma accidental als cultius a través de diverses formes, incloent l'ús de tripsina contaminada. Si es detecta la contaminació abans que totes les cèl·lules s'infectin, el virus pot ser eliminat a través de l'elaboració repetitiva de subcultius cel·lulars que continguin antisèrum PPV al medi de cultiu.

Molts són els investigadors que han utilitzat la microscopia d'immunofluorescència per tal de seguir el desenvolupament del PPV en cultius cel·lulars. En general, la seqüència dels events és la següent. Es detecta l'antigen viral al citoplasma de les cèl·lules poc després de la infecció si l'inòcul conté un títol elevat del virus i de l'antigen viral. La majoria, si no tota, d'aquesta fluorescència citoplasmàtica és el resultat de l'antigen fagocitat de l'inòcul. A través d'examinacions seqüencials, tal antigen pot ser primer mostrat a la superfície externa de la membrana citoplasmàtica i després dins del citoplasma, sovint concentrat relativament a una posició juxtanuclear. La primera evidència inequívoca de la replicació viral és l'aparició emergent d'antigen viral al nucli. En almenys algunes cèl·lules infectades, aquest antigen incipient apareix després al citoplasma en una quantitat suficient perquè tant el citoplasma com el nucli desprenguin fluorescència. Sovint les cèl·lules infectades observades als pulmons dels fetus que desenvolupen un major títol d'anticòs per a PPV representen aquest estadi de replicació. Les cèl·lules comencen a adoptar una forma arrodonida, esdevenen picnòtiques i es desintegren amb l'alliberament del virus i de l'antigen viral. Altres cèl·lules del cultiu que no es troben a la fase apropiada per la replicació viral continuen fagocitant i acumulant antigen viral al seu citoplasma. És possible induir una segona onada de replicació si s'estimulen aquestes cèl·lules a entrar a la fase S del cicle cel·lular a través de, per exemple, l'addició de medi de cultiu fresc.

Hemaglutinació
El PPV provoca hemaglutinació als eritròcits d'humans, micos, conillets d'Índia, gats, pollastres, rates i ratolins. S'ha observat que altres espècies animals en què s'han fet assajos són relativa o completament insensibles, o bé, els resultats van ser erronis.

Alguns paràmetres de la prova de l'hemaglutinació (HA) com la temperatura d'incubació, les espècies d'eritròcits usades i, en el cas dels pollastres, el component genètic i l'edat del donant, poden afectar els resultats.

La prova de l'hemaglutinació es duu a terme a temperatura ambient, a un pH neutre i normalment amb eritròcits de conillets d'Índia.

Els nivells més alts d'hemaglutinació s'han registrat quan el diluent utilitzat a la prova era el tampó veronal en lloc de la solució salina amb fosfat.

L'elució del virus pot ser induïda mitjançant la suspensió d'eritròcits en tampó alcalí, pH 9.

Infectivitat
Les valoracions de la infectivitat del PPV es duen a terme d'una manera estàndard, tenint en compte que, els canvis citopàtics a dilucions terminals són molt lents, els punts finals d'infectivitat es determinen molt sovint mitjançat l'examen de cultius cel·lulars d'inclusions intranuclears després d'una tinció adequada o bé amb l'examen del medi de cultiu cel·lular per hemaglutinina viral.

Els procediments de titració fan evidents les cèl·lules infectades mitjançant la tècnica d'immunofluorescència i també, en medis de cultiu.

Epidemiologia
El PPV és prevalent als porcs d'arreu del món i les infeccions per PPV són enzoòtiques a la majoria de les explotacions denses de porcs. En aquestes explotacions, aproximadament el 100% dels animals adults de més d'un any són seropositius. A més, una gran proporció de les truges primerenques estan infectades per PPV abans de concebre, i com a resultat desenvolupen una immunitat activa que probablement persisteix al llarg de la vida. En conjunt, les dates de seroepidemiologia indiquen que l'exposició enfront PPV és freqüent. També emfatitzen sobre l'alt risc d'infectar-se i de malaltia reproductiva entre les truges primerenques que no han desenvolupat immunitat abans de concebre. Les rutes més comunes d'infecció postnatal i prenatal són l'oronasal i la transplacentària, respectivament. També hi ha difusió intrauterina a fetus adjacents. Això es demostra per la gradació en la mida dels fetus momificats, corresponent al temps de mort fetal. El virus es transmet també per via orofecal, on les femtes amb virus seran la principal font de transmissió del virus al medi ambient.

Els garrins en néixer són seronegatius, però adquireixen passivament un títol important d'anticossos en mamar del calostre, ric en aquests. Aquest títol decreix progressivament a mesura que passa el temps mitjançant dilucions, ja que el garrí va creixent. Després de l'exposició d'animals seronegatius, el PPV es replica principalment en teixit limfoide i pulmons (concretament als limfòcits i macròfags alveolars), però es pot detectar a tots els teixits excepte al cervell. Els anticossos adquirits passivament protegeixen els garrins de la infecció per PPV entre 3 i 6 mesos si analitzem el sèrum amb el test HI. A vegades, els anticossos adquirits per aquest mètode poden persistir un interval de temps més llarg. La importància dels anticossos adquirits passivament és que interfereixen en el desenvolupament de la immunitat activa. Nivells alts d'aquests anticossos poden prevenir la infecció, i nivells baixos poden minimitzar la disseminació dels porcs infectats.

Les instal·lacions contaminades són probablement el major reservori del PPV. Aquest virus és termoestable, resistent a diferents desinfectants i manté la seva infectivitat durant mesos mitjançant secrecions i excrecions de porcs infectats de forma aguda. Va ser demostrat experimentalment que, tot i que els porcs transmetien el PPV durant només 2 setmanes després de l'exposició, les gàbies on havien estat podien transmetre la infecció durant 4 mesos. La ubiqüitat del PPV augmenta la possibilitat que alguns porcs estiguin persistentment infectats.

El verro susceptible, infectat per primera vegada durant la maduresa sexual, sofreix virèmia i el PPV podrà passar als òrgans genitals i contaminar el semen. Però en aquest cas no es produeix malaltia ni problemes de fertilitat. El virus estarà al semen durant el temps que duri la virèmia. Quan el verro adquireix immunitat s'elimina i, per tant, no produeix excreció permanent del virus. Independentment del seu estat d'immunitat, els verros també poden funcionar com a vehicle de disseminació de PPV entre les femelles susceptibles.

Patogènesi
L'única malaltia rellevant, reconeguda i associada amb la infecció porcina per PPV són els trastorns en la reproducció. En truges gestants està influenciada pel temps de gestació en el moment de la infecció i la soca del virus. Si la infecció es dona durant la primera meitat de la gestació provocarà trastorns reproductius. El PPV té la capacitat de travessar la barrera transplacentària arribant així a l'embrió o fetus. La infecció transplacentària requereix de 10 a 14 dies perquè succeeixi i pot haver-hi infecció intrauterina parcial dels garrins. Els fetus moren per dany col·lectiu dels teixits. El virus no afecta els teixits materns, l'única manifestació clínica que s'observa a les truges és el retorn a l'estre, però acostuma a passar desapercebut. Les conseqüències d'infectar-se durant aquest període poden ser mort embrionària i fetal, on hi hauria reabsorció i momificació, respectivament. S'obtenen resultats semblants quan s'inocula directament el fetus amb PPV fins als 70 dies de gestació. Això és degut al fet que al voltant dels 70 dies de gestació els fetus són ja capaços de desenvolupar una resposta immunològica protectora versus el virus. Taula 1. Etapes i conseqüències de la infecció per PPV en diferents intervals de la gestació.

Quan només part de la ventrada queda infectada via transplacentària, un o més garrins són infectats freqüentment per la subseqüent propagació intrauterina del virus. Passaria el mateix si la infecció inicial es produís per semen contaminat. Com a resultat, qualsevol combinació dels fets indicats a la Taula 1 poden desenvolupar-se en el mateix garrí.

L'efecte del PPV a l'òvul abans de l'ovulació encara no se sap, si és que n'hi ha. El virus s'adhereix a la superfície externa de la zona pel·lúcida de l'òvul fertilitzat i, encara que aparentment no pot travessar aquesta barrera, hi ha especulacions que podria ser una amenaça per a l'embrió després de l'eclosió (Wrathall and Mengeling 1979). La zona pel·lúcida protegeix l'embrió mentre la immunitat local s'està desenvolupant. D'altra banda, el virus podria causar canvis uterins incompatibles amb la gestació. De qualsevol manera, una femella infectada a través del semen proporciona un focus d'infecció per a altres.

Signes clínics i lesions
 El PPV causa trastorns reproductius. Després de la penetració a l'organisme es produeix una virèmia generalitzada, amb una replicació extensa. Podem trobar virus a diferents teixits i òrgans, especialment limfàtics i pulmonars. Es pot observar una lleugera leucopènia 10 dies després de la primera exposició al virus.

Les femelles no immunes són susceptibles a la infecció en qualsevol fase de la gestació, i com a conseqüència d'aquesta infecció es dona la transmissió a través de la placenta.

Un dels signes subclínics més importants en resposta a la infecció per PPV és un augment del fracàs reproductiu de les truges. Les seqüeles patològiques dependran del moment en què la truja sigui exposada al virus durant la gestació.

Les infeccions al principi de la gestació (fins al dia 35) provoquen una mort dels embrions i la seva reabsorció. Si la infecció es produeix entre els dies 35 i 70, aquests fetus ja no podran ser reabsorbits, ja que hi haurà una calcificació dels ossos dels fetus, i es produïra la seva mort i/o momificació. En cas de néixer algun garrí viu, ho farà molt debilitat. Per últim, si la infecció es produeix després del dia 70 de gestació, els garrins neixen vius, ja que, aquests fetus, en el moment de la infecció són ja capaços de crear una resposta immunitària en contra del PPV.

Les truges infectades no presenten cap mena de simptomatologia.

Les lesions fetals inclouen la mort, decoloració hemorràgica, acumulació de líquids a les cavitats corporals, reabsorció de líquids fetals i la momificació. Aquestes lesions no són apreciables en individus que hagin adquirit la capacitat immunitària contra el PPV en el moment de la infecció.

Diagnòstic
En una explotació porcina en la que es comença a tenir avortaments, ventrades petites i garrins momificats en diferents estats de desenvolupament 1 i algun de mort de manera que altera el ritme normal de producció, és signe de presència de PPV.El diagnòstic ha de ser confirmat per la demostració del virus als fetus momificats de menys de 70 dies de gestació, ja que les mares no presenten simptomatologia, 9 mitjançant tècniques que ens permetin detectar la presència de l'antigen del PPV. Es pot testar mitjançant proves específiques - com la immunofluorescència (la pràctica més segura), la immunoperoxidasa o amb sondes de DNA marcades radioactivament - en seccions congelades o talls histològics de pulmó i fetge.
La presència d'antígens del PPV pot ser demostrada als pulmons i al fetge dels garrins momificats, però no en els nascuts morts, en els que es pot trobar els anticossos específics contra el parvovirus als transsudats pleurals i peritoneals.

Diagnòstic al laboratori
Per fer un bon diagnòstic al laboratori es necessitarien mostres de fetus momificats i de residus fetals. Una alternativa seria usar el sèrum de truges, tant mares com joves, la primera mostra recollida al moment del fracàs reproductiu i la segona a les 2 o 4 setmanes després - ja que la vida mitjana dels anticossos maternals contra el PPV és d'uns 20 dies aproximadament. El sèrum dels fluids dels fetus, garrins morts o del cordó umbilical dels garrins vius sense que hagin pres calostre, també pot ser útil per a fer el diagnòstic d'anticossos específics del PPV.

Aïllament de l'agent
Per detectar el PPV en fetus amb una longitud de corona de "anca" menor a 16 cm per la seva activitat hemaglutinant o per anticossos fluorescents.

Serologia
Per detectar els anticossos del PPV en fetus amb una longitud de corona de "anca" major a 16 cm o en truges.

Efectes citopàtics
Els efectes citopàtics del PPV als cultius cel·lulars són inclusions intracel·lulars, nuclis picnòtics, granulacions, formes irregulars, replicació lenta i la mort cel·lular.

Reacció en cadena de la polimerasa (PCR)
La reacció en cadena de la polimerasa (PCR) és una tècnica amb alta sensibilitat i especificitat per a la detecció de virus en mostres clíniques, inclús millor que l'hemaglutinació. En aquest cas és la tècnica més útil per a la detecció de PPV en teixits fetals, semen i altres mostres - tal com s'ha descrit en nombrosos protocols de PCR.

Proves serològiques
Les proves serològiques són útils quan els teixits fetals no es troben amb bon estat.

Com que hi ha una alta prevalença de PPV i el temps entre la infecció i l'observació de pèrdues a la reproducció és llarg, s'usen dues mostres de sang i s'avalua en canvi de concentració d'anticossos (amb els títols) de les dues mostres.

Inhibició de l'hemaglutinació (IH)
El PPV té la capacitat d'hemaglutinar els eritròcits, de manera que es pot usar aquesta propietat per detectar la presència d'anticossos que s'uneixen als epítops dels factors d'hemaglutinació del virus, de manera que s'inhibeix l'hemaglutinació.

La inhibició de l'hemaglutinació (IH) és la pràctica més usada per a quantificar els anticossos específics del PPV. Els resultats es poden veure afectats per la temperatura d'incubació o per la font dels eritròcits. El sèrum usat per al diagnòstic és pretractat per inactivació amb calor (56 °C durant 30 minuts) seguit d'una adsorció dels eritròcits per tal d'eliminar les hemaglutinines no específiques i els inhibidors de l'hemaglutinació.

En els tests IH, si la porció hemaglutinant del virus reacciona amb els anticossos específics del sèrum problema, l'hemaglutinació dels eritròcits es bloqueja de manera que veurem un punt d'eritròcits al fons del pou de la microplaca - donant un resultat positiu de la prova, ja que els anticossos contra aquest antigen hi són presents. D'altra banda, si els eritròcits s'aglutinen després d'afegir el sèrum, significarà que el sèrum no contenia els anticossos correctes i veurem una taca al fons del pou de la microplaca.
El sèrum dels porcs ha de ser tractat prèviament per tal d'eliminar les hemaglutinines o els inhibidors de l'hemaglutinació no específics, com hem dit anteriorment, i a les proves s'usa un sèrum inicial diluït al 1:10, i a partir d'aquest, es van fent dilucions per obtenir el títol correcte - màxima dilució del sèrum amb presència d'anticossos perquè la prova sigui positiva.

ELISA
L'ELISA és preferible a la IH perquè es pot fer de manera estàndard i automatitzada per a proves d'alt nivell i no requereix un pretractament del sèrum abans de ser testat. ELISA pot distingir els animals vacunats dels animals infectats per PPV.

Les vacunes inactivades només provoquen la producció d'anticossos contra les proteïnes estructurals, mentre que ELISA detecta els anticossos contra les proteïnes no estructurals tipus 1 que expressa el virus durant la seva replicació en els porcs infectats.

Tractament i prevenció
No existeix cap tractament contra la infertilitat induïda pel parvovirus porcí (PPV).

Per tal de prevenir la malaltia, mentre hi hagi símptomes de la infecció no es poden comprar nous animals. A més, les truges nulípares han de ser infectades amb PPV o vacunades abans de la primera inseminació. Aquelles truges que hagin superat la infecció es podran seguir utilitzant per a la reproducció sempre que tornin a tenir el cicle estral i quedin gestants. Els animals que ja han passat la infecció seran immunes.

Mètodes d'immunització:

 Immunització natural: Consisteix a infectar a les truges seronegatives a partir de posar-les en contacte amb truges seropositives que estiguin excretant el virus o bé traslladar a les truges joves a una zona que estigui contaminada pel PPV. No és un mètode fiable, però, perquè no es pot assegurar que tots els animals negatius quedin infectats i també és perillós perquè es pot donar la difusió d'altres patògens.

 Vacunació: És l'únic mètode de garantir que les truges joves desenvolupin una immunitat activa enfront al PPV abans de la primera cubrició. Les vacunes tenen l'objectiu d'oferir-li una immunitat abans i durant el període de gestació. No obstant, la vacuna s'ha de realitzar després que desaparegui la immunitat calostral en les nulípares. Per tal de vacunar a les truges s'han de seguir unes pautes vacunals; la primera vacuna s'ha de subministrar en dues dosis separades entre 3-4 setmanes abans de la cubrició i després és necessari realitzar una revacunació en cada lactació uns 7-10 dies després del part.

També és important vacunar els verros, ja que és un mètode preventiu per disminuir la diseminació de la malaltia. S'ha de fer una primera vacuna en dues dosis 4 setmanes abans de la munta i una revacunació cada 4-6 mesos.

Les vacunes clàssiques contra malalties greus causades per parvovirus estan basades en l'ús d'agents químics inactivants com ara l'acetiletileneimina o la propiolactona en el PPV, i la formalina en el virus de l'enteritis del visó (MEV). La capacitat d'autoacoblament de les càpsides de parvovirus en sistemes d'expressió heteròlegs està canviant radicalment aquest escenari cap a vacunes més efectives i segures basades en càpsides buides purificades (partícules similivíriques, o virus-like particles (VLPs) en anglès), obtingudes fonamentalment de vectors de baculovirus. Les vacunes poden ser, doncs, vacunes inactivades (KV), utilitzades quan l'explotació és negativa a PPV; i també vacunes vives modificades (MLV), que indueixen una resposta immune de llarga durada. Totes elles pretenen produir un nivell d'immunitat suficient en les truges gestants per tal de reduir la virèmia a un nivell on és poc probable que el virus pugui travessar la placenta.

Cal recordar que qualsevol vacuna ha de ser administrada sota la supervisió d'un veterinari. La duració de la immunitat no es pot preveure, encara que hi ha estudis que demostren l'eficàcia fins quatre mesos després de l'administració d'una vacuna inactivada.

En general, les respostes serològiques després de la vacunació són més baixes que les de la infecció natural.

Referències

Bibliografia
 Jeffrey J.Zimmerman, Locke A.Karriker, Alejandro Ramirez, Kent J.Schwartz and Gregory W.Stevenson. Diseases of swine. 10th edition. USA. Wiley-Blackwell; 2012
Gava, D., Wentz, I., 'Perfil inmunologico del parvovirus porcino frente a dieferentes desadios sanitarios'. Revista Avances. 2013. : http://revistaavances.com/perfil-inmunologico-del-parvovirus-porcino-frente-a-diferentes-desafios-sanitarios/')
Sanchez Murillo, J.M. et al., 'Parvovirosis porcina'. Mundo ganadero. 1993-11. Ministerio de agricultura y medio ambiente. 1993

Virus d'ADN monocatenari
D.J. Taylor, 7th edition, Pig Deseases, St Edmundsbury Press, Great Britain
W.J. Smith, D.J. Taylor, R.H.C Penny, Atlas en color de Patologia Procina, Interamericana McGrau Hill, Espanya
D.C. Blood, J.A. Henderson, O.M. Radostits, 6th edition, Medicina Veterinaria, Bailliere Tindall, Mexico
8th edition, The Merck Veterinary Manual, National Publishing Inc., USA
(Sanchez Murillo, J.M. et al., 'Parvovirosis porcina'. Mundo ganadero. 1993-11. (Ministerio de agricultura y medio ambiente. 1993)
A. D. Leman, Barbara Straw et al., "Diseases of swine". 6th edition, IOWA STATE UNIVERSITY PRESS.
repositorio.utc.edu.ec/bitstream/27000/816/1/T-UTC-1175%281%29.pdf
http://issuu.com/instituto_leblu/docs/separata_hipra_75_web

redpajama_set_name: RedPajamaWikipedia


Al-Haq has documented increased pressure by the Jerusalem municipality on residents and business owners in Beit Hanina located near the Israeli settlement of Atarot. Local Palestinians have linked the increase in inspections and fines to the construction of a new "Rami Levy" supermarket and shopping complex in the settlement.
A homeowner located next to the carwash and also across the street from the "Rami Levy" project also highlighted increased visits by the Jerusalem Municipality, resulting in her having to self-demolish part of her home.
These cases both highlight the precarious position of countless Palestinians in East Jerusalem that face demolition or confiscation of their property due to Israel's discriminatory building and planning system. Al-Haq is concerned that Palestinian residents and business owners in Beit Hanina and nearby areas will continue to be targeted by the Jerusalem Municipality as Atarot settlement develops.
Al-Haq further calls attention to the severe impact that the "Rami Levy" project will have on local residents, as already seen by the aforementioned cases, and the economy as a whole. Because Israeli authorities rarely issue building permits for Palestinians, individuals living in East Jerusalem neighborhoods near Atarot, like Beit Hanina and Shu'fat, do not and will not have comparable large retail facilities.  Smaller businesses will likely be unable to compete with the settlement mall. Al-Haq reminds business owners that businesses benefiting from Israel's illegal settlement enterprise, and the violations of international humanitarian and human rights law that it propagates, may be found complicit in aiding and abetting these violations even where they do not positively assist in orchestrating the abuse.
 Al-Haq Affidavit 2016/347 taken on23 April 2016. Al-Haq spoke with Nidal on 22 June 2016, and he stated that the municipal employee has come numerous times in June and has continued to issue fines.
 Al-Haq Affidavit 2016/346 taken on 18 April 2016.


text:
Q: PHP regex return zero result i have following PHP curl and regex code. i'd like to get post header from website. In actual, there are 10 articles. but code returns zero result.
PHP:
<?php
$ch = curl_init();
$url = "www.mahsumakbas.net";
curl_setopt($ch, CURLOPT_URL, $url);
curl_setopt($ch, CURLOPT_HEADER, FALSE);
curl_setopt($ch, CURLOPT_RETURNTRANSFER, TRUE);
$content = curl_exec($ch);
curl_close($ch);

@preg_match_all('/
(.*)<\/h2>/' ,$content, $matches);

for ($i=0;  $i< sizeof($matches[1]); $i++)
    echo $matches[1][$i]."
";

?>

On www.mahsumakbas.net web page there are 10
 enclosed with

what do i miss?

A: Try this:
$url = "www.mahsumakbas.net";
$c = curl_init($url);
curl_setopt($c, CURLOPT_RETURNTRANSFER, true);
//curl_setopt(... other options you want...)
$html = curl_exec($c);

curl_close($c);
preg_match_all("'
(.*?)
'si" ,$html, $matches);

foreach($matches[1] as $key=>$val)
    echo $val."
";

A: Your headlines are build in 3 lines. You must set the "m"-option. Maybe it helps.
http://php.net/manual/en/reference.pcre.pattern.modifiers.php
But for parsing a HTML-DOM string you should use DOMDocument with getElementByTagName

redpajama_set_name: RedPajamaStackExchange


text:
package hk.ust.gmission.authenticator;

import android.accounts.Account;
import android.accounts.AccountManager;
import android.app.Dialog;
import android.app.ProgressDialog;
import android.content.DialogInterface;
import android.content.Intent;
import android.os.Bundle;
import android.text.TextUtils;
import android.util.Log;
import android.view.MenuItem;
import android.widget.AutoCompleteTextView;
import android.widget.Button;
import android.widget.EditText;
import android.widget.TextView;

import com.github.kevinsawicki.http.HttpRequest;
import com.github.kevinsawicki.wishlist.Toaster;
import com.google.gson.Gson;
import com.jakewharton.rxbinding.view.RxView;
import com.jakewharton.rxbinding.widget.RxTextView;

import java.util.concurrent.TimeUnit;

import butterknife.Bind;
import butterknife.ButterKnife;
import hk.ust.gmission.R;
import hk.ust.gmission.core.Constants;
import hk.ust.gmission.models.User;
import hk.ust.gmission.util.Ln;
import hk.ust.gmission.util.Strings;
import rx.Observable;
import rx.Observer;
import rx.Subscription;
import rx.android.schedulers.AndroidSchedulers;
import rx.functions.Action0;
import rx.functions.Action1;
import rx.functions.Func1;
import rx.functions.Func4;
import rx.schedulers.Schedulers;
import rx.subscriptions.CompositeSubscription;

import static android.accounts.AccountManager.KEY_ACCOUNT_NAME;
import static android.accounts.AccountManager.KEY_ACCOUNT_TYPE;
import static android.accounts.AccountManager.KEY_AUTHTOKEN;
import static android.accounts.AccountManager.KEY_BOOLEAN_RESULT;
import static android.text.TextUtils.isEmpty;
import static android.util.Patterns.EMAIL_ADDRESS;
import static com.github.kevinsawicki.http.HttpRequest.post;

public class BootstrapAccountRegisterActivity extends ActionBarAccountAuthenticatorActivity {

    @Bind(R.id.et_name) EditText mEtUsername;
    @Bind(R.id.et_email) AutoCompleteTextView mEtEmail;
    @Bind(R.id.et_password) EditText mEtPassword1;
    @Bind(R.id.et_password2) EditText mEtPassword2;
    @Bind(R.id.b_signin) Button mBSigninBtn;
    @Bind(R.id.tv_notice) TextView mTvNotice;

    private CompositeSubscription subcriptions = new CompositeSubscription();

    private Observable<CharSequence> nameChangeObservable;
    private Observable<CharSequence> emailChangeObservable;
    private Observable<CharSequence> passwd1ChangeObservable;
    private Observable<CharSequence> passwd2ChangeObservable;

    private AccountManager accountManager;

    String username;
    String passwd;
    String email;
    private String token = null;

    private String accountId = null;

    private String authToken;
    private String authTokenType;

    private static int BUTTON_PRESS_DELAY_MILLIS = 1000;

    @Override
    protected void onCreate(Bundle savedInstanceState) {
        super.onCreate(savedInstanceState);
        setContentView(R.layout.account_register_activity);
        ButterKnife.bind(this);

        nameChangeObservable = RxTextView.textChanges(mEtUsername).skip(1);
        emailChangeObservable = RxTextView.textChanges(mEtEmail).skip(1);
        passwd1ChangeObservable = RxTextView.textChanges(mEtPassword1).skip(1);
        passwd2ChangeObservable = RxTextView.textChanges(mEtPassword2).skip(1);

        accountManager = AccountManager.get(this);

        combineLatestEvents();
        subscribeRegisterButton();

    }

    @Override
    public void onPause() {
        super.onPause();
        subcriptions.unsubscribe();
    }

    private void combineLatestEvents() {
        Subscription formSubscription = Observable.combineLatest(nameChangeObservable,
                emailChangeObservable,
                passwd1ChangeObservable,
                passwd2ChangeObservable,
                new Func4<CharSequence, CharSequence, CharSequence, CharSequence, Boolean>() {
                    @Override
                    public Boolean call(CharSequence newName,
                                        CharSequence newEmail,
                                        CharSequence newPasswd1,
                                        CharSequence newPasswd2) {

                        boolean nameValid = !isEmpty(newName) && newName.length() >= 6;
                        if (!nameValid) {
                            mTvNotice.setText(getString(R.string.register_check_name));
                        } else {
                            username = newName.toString();
                        }

                        boolean emailValid = !isEmpty(newEmail) &&
                                EMAIL_ADDRESS.matcher(newEmail).matches();
                        if (!emailValid) {
                            mTvNotice.setText(getString(R.string.register_check_email));
                        } else {
                            email = newEmail.toString();
                        }

                        boolean passValid1 = !isEmpty(newPasswd1) && newPasswd1.length() >= 6;
                        if (!passValid1) {
                            mTvNotice.setText(getString(R.string.register_check_passwd));
                        }

                        boolean passValid2 = TextUtils.equals(newPasswd1, newPasswd2);
                        if (!passValid2) {
                            mTvNotice.setText(getString(R.string.register_check_password_same));
                        } else {
                            passwd = newPasswd2.toString();
                        }

                        return nameValid && emailValid && passValid1 && passValid2;

                    }
                })
                .doOnNext(new Action1<Boolean>() {
                    @Override
                    public void call(Boolean formValid) {
                        if (formValid)mTvNotice.setText("");
                        mBSigninBtn.setEnabled(formValid);
                    }
                })
                .subscribe();

        subcriptions.add(formSubscription);
    }

    private void subscribeRegisterButton(){

        Subscription buttonSubscription = RxView.clicks(mBSigninBtn)
                .debounce(BUTTON_PRESS_DELAY_MILLIS, TimeUnit.MILLISECONDS)
                .observeOn(AndroidSchedulers.mainThread())
                .map(new Func1<Object, Object>() {
                    @Override
                    public Object call(Object o) {
                        showProgress();
                        return o;
                    }
                })
                .doOnError(new Action1<Throwable>() {
                    @Override
                    public void call(Throwable e) {
                        Throwable cause = e.getCause() != null ? e.getCause() : e;

                        String message;
                        // A 404 is returned as an Exception with this message
                        if ("Received authentication challenge is null".equals(cause.getMessage())){
                            message = getResources().getString(R.string.message_reg_error);
                        }
                        else {
                            message = cause.getMessage();
                        }

                        Toaster.showLong(BootstrapAccountRegisterActivity.this, message);
                        hideProgress();
                    }
                })
                .observeOn(Schedulers.io())
                .map(new Func1<Object, Object>() {

                    @Override
                    public Object call(Object o) {
                        final String query = String.format("{\"username\":\"%s\", \"password\":\"%s\", \"email\":\"%s\"}", username, passwd, email);

                        Log.i("PostContent", query);
                        HttpRequest request = post(Constants.Http.URL_REG).contentType(Constants.Http.CONTENT_TYPE_JSON).send(query);

                        Log.i("REGISTER", "Authentication response=" + request.code());

                        if (request.ok()) {
                            final User model = new Gson().fromJson(Strings.toString(request.buffer()), User.class);

//                            if(!model.isActive()) return;

                            model.setEmail(email);
                            token = model.getToken();
                            accountId = String.valueOf(model.getId());
                        }

                        onRegistrationResult(request.ok());
                        return o;
                    }
                })
                .observeOn(AndroidSchedulers.mainThread())
                .doOnNext(new Action1<Object>() {
                    @Override
                    public void call(Object o) {
                        hideProgress();
                    }
                })
                .subscribe();
        subcriptions.add(buttonSubscription);
    }

    /**
     * Hide progress dialog
     */
    @SuppressWarnings("deprecation")
    protected void hideProgress() {
        dismissDialog(0);
    }

    /**
     * Show progress dialog
     */
    @SuppressWarnings("deprecation")
    protected void showProgress() {
        showDialog(0);
    }

    protected void finishLogin() {
//        final Account account = new Account(username, Constants.Auth.BOOTSTRAP_ACCOUNT_TYPE);
//
//        authToken = token;
//        Constants.Http.PARAM_SESSION_TOKEN = authToken;
//        accountManager.addAccountExplicitly(account, passwd, null);
//        accountManager.setAuthToken(account, Constants.Auth.AUTHTOKEN_TYPE, authToken);
//        accountManager.setUserData(account, Constants.Auth.USER_ID, accountId);
//
//        final Intent intent = new Intent();
//        intent.putExtra(KEY_ACCOUNT_NAME, username);
//        intent.putExtra(KEY_ACCOUNT_TYPE, Constants.Auth.BOOTSTRAP_ACCOUNT_TYPE);
//
//        if (authTokenType != null
//                && authTokenType.equals(Constants.Auth.AUTHTOKEN_TYPE)) {
//            intent.putExtra(KEY_AUTHTOKEN, authToken);
//        }
//
//
//
//        intent.putExtra( KEY_BOOLEAN_RESULT, accountId);
//
//        setAccountAuthenticatorResult(intent.getExtras());
//        setResult(RESULT_OK, intent);

        finish();
    }

    public void onRegistrationResult(boolean result) {
        if (result) {
            Toaster.showLong(BootstrapAccountRegisterActivity.this,
                    getResources().getString(
                            R.string.message_reg_ok));
            finish();
        } else {
            Toaster.showLong(BootstrapAccountRegisterActivity.this,
                    getResources().getString(
                            R.string.message_reg_error));
        }
    }

    @Override
    protected Dialog onCreateDialog(int id) {
        final ProgressDialog dialog = new ProgressDialog(this);
        dialog.setMessage(getText(R.string.message_signing_up));
        dialog.setIndeterminate(true);
        dialog.setCancelable(true);
        dialog.setOnCancelListener(new DialogInterface.OnCancelListener() {
            public void onCancel(final DialogInterface dialog) {

            }
        });
        return dialog;
    }

    @Override
    public boolean onOptionsItemSelected(MenuItem item){
        finish();
        return true;

    }
}


text:
New opening times Tues - Fri 10am - 5pm & Sat 9am - 5pm Closed Sun/Mon
New LP's
Second Hand Vinyl
Record Cleaning Service
Record Players & Accessories
Home › Beck - Sea Change
Beck - Sea Change
Beck's seventh album, Sea Change, signified a dramatic musical shift in sound and tone from its predecessor, the funky, R&B-influenced Midnite Vultures, and as its title suggested, was a profound transformation. Inspired by the dissolution of a longtime relationship, Beck transformed his sadness into both his most personal and beautiful record to date, trading his trademark sample-filled songs and impressionistic, irreverent lyrics for pensive melodies, sweeping strings and direct, confessional lyrics. Produced by Nigel Godrich, the album, which peaked at #8 on the Billboard 200, was made with a full band which included guitarist Smokey Hormel, keyboard player Roger Manning, drummer Joey Waronker; Beck's father, David Campbell, provided string arrangements. While widely praised upon release in 2002, the album has only grown in stature. Rolling Stone's David Fricke hailed it as "the best album Beck has ever made," adding it's his "Blood On The Tracks," and the record was listed in their 2009 definitive list of the "500 Greatest Albums of All Time" and the "100 Best Albums of the 2000s." In SPIN's 10-year anniversary piece, they declared it "the best melancholy album of the millennium" while The Guardian called it "his masterpiece." The album will be released as a double LP with a download card featuring 320kbps AAC MP4 audio files of the entire album.
1. The Golden Age
2. Paper Tiger
3. Guess I'm Doing Fine
4. Lonesome Tears
5. Lost Cause
6. End Of The Day
7. It's All In Your Mind
8. Round The Bend
9. Already Dead
10. Sunday Sun
11. Little One
13. Side Of The Road
Dio - Sacred Heart
Dio - Dream Evil
Dio - The Last In Line
Dio - Holy Diver
For news on new releases and any upcoming events in the world of vinyl, please follow us on Twitter and Facebook. We can also be found on Instagram where you...
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About UC Davis Health
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Welcome to the UC Davis Health newsroom. Below you will find the latest health and medicine news from UC Davis. If you are a journalist, our news service staff is available to help identify sources for stories about patient care, research and education. Also please review important information for journalists for details about patient privacy and arranging for interviews at health system facilities.
Why aren't advanced bladder cancers being treated?
Patients with advanced bladder cancers are not getting the treatment they need. UC Davis Health urologic oncologists are working to change that. Their paper in the Journal of Clinical Oncology describes the problem and suggests how to fix it.
UC Davis Health surgeons publish novel tumor-removal technique
A new approach, which involves placing endovascular stents into the aorta and/or vena cava, was developed to help make the removal of complex testicular tumors safer.
Lecture focuses on the therapeutic possibilities of psychedelics
University of New Mexico physician and researcher Lawrence Leeman will speak in Sacramento about the possibilities of using psychedelic-assisted psychotherapy to treat PTSD, opioid use disorder and depression.
UC Davis Health welcomes internationally renowned robotic heart surgeon as the new chief of cardiothoracic surgery
Internationally acclaimed heart surgeon Bob Kiaii has been selected as chief of the Division of Cardiothoracic Surgery at UC Davis Health, ranked one of the best cardiology and heart surgery programs in the nation.
A creative approach to addressing chronic pain
Pain management specialists at UC Davis Health are seeking individuals suffering from chronic pain for a study that evaluates how museum-based art programs may help address pain-related problems.
Levenson named fellow of international society for optics and photonics
UC Davis researcher recognized for microscope that uses ultraviolet light to assess tissue biopsies, eliminates need for traditional slide preparation
Partnership encourages Native Americans to pursue health care careers
UC Davis School of Medicine takes steps to increase enrollment of Native American students
Community Conversations Science Café to explore early detection of lung cancer
In an open community event, Dr. David Cooke will discuss the importance of early detection of lung cancer and the current disparities in screening for it.
'GI Treatment Approaches in Autism' is the next Minds Behind the MIND lecture
In the next Minds Behind The MIND series, pediatricians Kathleen Angkustsiri and Bibiana Restrepo will present on gastrointestinal (stomach) symptoms in children with autism spectrum disorder.
What a UC Davis Health dietitian is eating in 2020
UC Davis Health registered dietitian and certified diabetes educator Alex Nella answers some of the questions he gets most often about diet and nutrition.
VIDEO: TAVR team celebrates an important milestone
UC Davis Health was the first to offer transcatheter aortic valve replacement (TAVR) in the Sacramento and today is a leading referral center for the procedure. On December 16, the TAVR team completed their 1,000th procedure.
New year, better skin
UC Davis Health dermatologist Oma Agbai has some easy tips that will have your skin healthier than ever in 2020.
Medicaid expansion associated with fewer total opioid overdose deaths across the U.S.
Expanding Medicaid under the Affordable Care Act may have saved as many as 8,132 people from fatal opioid overdoses, virtually all involving heroin and fentanyl, a study by UC Davis Violence Prevention Research Program and NYU School of Medicine shows.
UC Davis Health radiation safety officer to serve on National Academy of Sciences study
A UC Davis Health employee for nearly 32 years, Linda Kroger brings decades of experience and expertise to a study of alternatives to high-level radioactive materials in commercial and medical applications.
VIDEO: UC Davis nursing school opens applications for nurse leader fellowships
Applications are now open for a new fellowship program for nursing scholars and innovators with a high potential to accelerate leadership in nursing research, practice, education, policy and entrepreneurship.
VIDEO: Exercising 30 minutes each day is easier than you think
Think you don't have time to exercise? Sports medicine physician Brandee Waite helps you work out smarter in shorter timeframes.
Survey finds public support for two California firearm policy proposals
The results of a new survey, published Jan. 8 as a research letter in JAMA Network Open, suggest firearm owners and non-owners generally agree on policies aimed at preventing firearm injury and death.
Five reasons why "Dry January" can give your body a boost
By taking a sober approach to the new year, the health benefits include weight loss, better sports performance, better sleep, better sex and a longer life.
Award-winning filmmaker Janet Grillo to speak at the MIND Institute
Emmy Award-winning filmmaker Janet Grillo to speak at the UC David MIND Institute.
Applications sought for Children's Miracle Network Grants
Grant applications are now being accepted for funds raised through activities of the Children's Miracle Network (CMN), which provides financial support for UC Davis Children's Hospital.
Five ways to protect brain health
Learn how to make the most of your brain and help reduce some risks as you age.
Donut Dash raises funds for UC Davis Child Life on March 7
The 12th annual Donut Dash will take place Saturday, March 7, at 8:30 a.m. at William Land Park in Sacramento. Proceeds will benefit the UC Davis Child Life and Creative Arts Therapy Department.
Prostate biopsies enhanced with state-of-the-art imaging system
ExactVu, a state-of-the-art ultrasound device, is now being used by the UC Davis Department of Urologic Surgery to more precisely visualize prostate tumors for a better quality biopsy.
Video visits bring ease, convenience to patients at UC Davis Health
A visit with your health care provider is now available through your smartphone, thanks to the Video Visit program at UC Davis Health.
Tips for flu prevention
Depending on your age and health, the flu can be a minor nuisance or a threat to your life. With cases currently on the rise, it is a good time to take steps to protect yourself.
Yuba City retiree gets a surprise cancer diagnosis
A routine screening leads to a surprising diagnosis and treatable bladder tumor for Yuba city man.
UC Davis Children's Hospital hosts pop-up toy store for parents of hospitalized children
Parents of hospitalized kids had the chance to shop today as the Child Life and Creative Arts Therapy Department at UC Davis Children's Hospital held its annual Holiday Workshop.
Erik Fernandez y Garcia appointed to First 5 Sacramento Commission
Erik Fernandez y Garcia, associate professor of clinical pediatrics, was appointed this week to the First 5 Sacramento Commission by the Sacramento County Board of Supervisors.
Three nursing teams earn PRISM awards, making UC Davis Medical Center No. 1 in state
Three UC Davis Medical Center nursing units earned national recognition this week for exemplary patient care and professional development achievements.
CA Quits honors FQHCs for tobacco cessation e-referral programs
The Sacramento County Primary Care Center and One Community Health were recently honored for integrating e-referrals between their providers and the California Smokers' Helpline.
VIDEO: Heading to the slopes? Do these two things first
A little preparation can help you have more fun and worry a lot less about injuries on the slopes this winter.
'Just another member within the community': Officer Justin Williams, the humble hero
There's no doubt Justin Williams is a tough guy, in the words of his former running backs coach at UC Davis. But Williams, in his current role as a UC Davis police officer, also serves our community with empathy and compassion.
MS doctor also provides community care
Mustafa Ansari is a UC Davis specialist in multiple sclerosis who also practices general neurology at the County of Sacramento Primary Care Center.
VIDEO: From patient to professional
Graduate nursing student Jason Ramos reunites with the nurse who saved his life and prepares for a career to care for others as he was cared for at UC Davis Health.
VIDEO: UC Davis nursing students mark end of graduate program with traditional pinning ceremony
Graduate students from the Betty Irene Moore School of Nursing celebration the completion of their studies and look forward to entering the nursing profession.
VIDEO: Bus tour connects UC Davis Health with Central Valley communities, gains national recognition
Students from the UC Davis schools of nursing and medicine experience the Central Valley region and learn how to better serve those populations.
Students get up-close learning about sickle cell disease
Students learn from UC Davis Health experts and patients about sickle cell disease as part of a partnership between their Elk Grove school and the Division of Hematology and Oncology.
Comprehensive background check policies effective in Oregon but not in Washington
Did newly enacted laws result in more background checks for private-party sales – the major source of guns for persons who commit crimes and are prohibited from owning them? A UC Davis Violence Prevention Research study reviewed the data.
Ton selected as UC Davis Health Associate Vice Chancellor for Health Equity, Diversity and Inclusion
The Interim Associate Vice Chancellor for Diversity and Inclusion at UC Davis Health since 2017, Hendry Ton will manage and direct health equity, diversity and inclusion programs and initiatives across the Health campus.
49ers star, Sacramento native delivers toys to UC Davis Children's Hospital
San Francisco 49ers star and Sacramento native Arik Armstead brought holiday cheer to UC Davis Children's Hospital by delivering toys to children undergoing treatment.
Liu named to National Academy of Inventors
The National Academy of Inventors recently elected 168 new fellows, including Fu-Tong Liu, emeritus professor and chair of the UC Davis Department of Dermatology.
VIDEO: The Art of Healing
For more than 35 years, UC Davis Health has been acquiring and displaying the unique works of local artists. Art has healing qualities, and UC Davis' collection is designed to enrich the lives of patients, families, students and staff.
Meaningful change in culture urged to save neurology, reduce gender gap
UC Davis School of Medicine Dean Allison Brashear and Nina F. Schor, deputy director at the National Institute of Neurological Disorders and Stroke, are working to save neurology and to reduce the gender gap in the medical specialty.
Employees invited to receive free hand-crafted items for loved ones with Alzheimer's, Dec. 10 from 11 a.m. to 1 p.m.
According to social worker Esther Lara, the gift of a blanket or shawl gives Alzheimer's patients so much more than warmth. It has a comforting and soothing effect. Pick up an item to share.
2018 California Safety and Wellbeing Survey details firearm ownership in the state
UC Davis researchers asked Californians if they owned firearms and when, where and how they got them. They estimated 4.2 million California adults personally own a gun, and an additional 3.1 million live in a home with someone else who does. Find out more.
Sacramento Modular Railroaders thanked for almost a decade of service to UC Davis Children's Hospital
Going to the doctor's office is not something kids typically look forward to. Unless, that is, they're headed to the pediatric specialty clinic at the Glassrock Building at UC Davis Health where a train runs continuously and has for years, thanks to a local group of railroad enthusiasts.
Out-of-state family chooses UC Davis Children's Hospital for life-changing heart procedure
Internationally renowned interventional cardiologist Frank Ing does for Katie Herrmann what others can't: perform a patent ductus arteriosus (PDA) closure on the tiniest of patients.
New funding for high-tech approaches for detecting Alzheimer's in women and communities of color
Machine-learning approaches to detect abnormalities in blood vessels associated with dementia and liquid biopsy-guided strategies to define dementia across disease stages are two exciting areas funded prevent Alzheimer's disease.
Lars Berglund is the new Editor-in-Chief of the Journal of Clinical and Translational Science
Lars Berglund will serve as the new editor-in-chief of the Journal of Clinical and Translational Science, effective January 1, 2020.
New memorial at School of Medicine honors those who donate their bodies to science
Medical school leaders dedicate tribute to body donation program
First of its kind study seeks to answer whether the effects of the "abortion pill" can be reversed
Women who initiate medical abortion but opt to stop in the middle of treatment may be at risk for serious blood loss, a UC Davis Health study finds.
UC Davis nursing school receives $37.5 million from Gordon and Betty Moore Foundation to support nurse leaders and innovators, expand national impact
The Gordon and Betty Moore Foundation grants UC Davis $37.5 million to establish a national fellowship program for nurse leaders and innovators.
Enroll in UC Davis' mini medical school
Get ready for UC Davis' 18th annual Mini Medical School, the highly regarded six-week curriculum that prepares attendees for life's second half. Enroll in the engaging series of classes, which begin Feb. 1, 2020 and run for six Saturdays.
More than 200 UC Davis Health physicians named 'Top Docs'
UC Davis Health physicians named among Sacramento Magazine's Top Docs practice in more than 60 specialty areas, including 16 pediatric subspecialties.
Medical school training program is transforming health care in California
The UC Davis PRIME program trains medical students to better serve the state's evolving health needs
Neurological surgery professor elected as AAAS fellow
UC Davis Health neuroscientist, Robert Berman, has been elected as a AAAS fellow for his contributions to understanding traumatic brain injury, autism and Fragile-X-related disorders.
How to have heart-healthy holidays
A UC Davis Health dietitian offers guidance for making it through the holidays without compromising healthy eating goals.
Sex, drugs and arrhythmia: Modeling approaches to enable precision cardiac pharmacology
To promote cardiac safety, researchers at the GRANDi laboratory are using computer simulations to understand and predict the impact of new drugs on the cardiac cells.
Clinical trials now searchable through MyUCDavisHealth portal
Through new functionality on the web portal, UC Davis Health patients can browse studies currently seeking volunteers and take the first steps to participate in cutting-edge research.
Lung cancer screening campaign brings message to the community
UC Davis Health and community leaders join forces to kick off lung cancer screening campaign.
UC Davis Health Joins ACRP's Clinical Research 'Workforce Innovation Steering Committee'
UC Davis Health has joined the Association of Clinical Research Professionals as the latest member of its "Workforce Innovation Steering Committee" for improving training and development for the clinical research workforce.
Diana Farmer recognized for global leadership
UC Davis Health's leading pediatric and fetal surgeon has won a 2020 U21 Award.
UC Davis researchers recognized for being highly cited
Sixteen UC Davis researchers – six from the School of Medicine - have been recognized in the annual Highly Cited Researchers 2019 list.
Customized human milk provides targeted nutrition for premature babies
Premature babies in the Neonatal Intensive Care Unit at UC Davis Children's Hospital will get customized breast milk, fortified with the nutrients, thanks to a new Miris human milk analyzer machine donated by the Children's Miracle Network.
Antibiotic resistance now poses bigger problems than previous estimates
Deadly superbugs that have developed a resistance to antibiotics are on the rise. UC Davis Health experts are helping lead efforts to address this dangerous trend.
Constantly connected: A webcam for every NICU bed
All Neonatal Intensive Care Unit (NICU) beds at UC Davis Children's Hospital are now set up with a webcam, providing parents and families with a 24/7 lifeline to see their baby remotely.
Mapping the pathway to gut health in HIV and SIV infections
Study found that a strain of bacteria rapidly repaired damaged gut lining (known as leaky gut) in monkeys infected with chronic simian immunodeficiency virus (SIV), an HIV-like virus.
UC study estimates mild cognitive impairment among diverse Latino populations at 10%
A study of over 6,300 Latinos of Dominican, Central American, Cuban, Mexican Puerto Rican and South American heritage estimates that nearly 10% of middle-age and older Latinos in the U.S. meet the criteria for mild cognitive impairment.
Opioid prescription doses are increasingly being tapered, often more rapidly than recommended
New research shows that opioid dose tapering can occur at rates much higher than recommended, increasing the risks of withdrawal, uncontrolled pain or mental health crises.
Farmer becomes a regent of the American College of Surgeons
Diana Farmer has been elected to the Board of Regents of the American College of Surgeons (ACS). The 24-member board formulates policy and directs the affairs of the ACS.
Lloyd Michener to share practical strategies to promote community engagement in health centers
Lloyd Michener from Duke University School of Medicine will present at the Community Engagement Seminar Series on Nov. 21 on how academic health centers can better engage their communities.
UC Davis nursing professors named distinguished gerontological educators
Three faculty from the Betty Irene Moore School of Nursing at UC Davis are recognized for their expertise in gerontological nursing.
Frederik Shic to present on everyday technologies in the lives of children with autism
Frederik Shic will present on Nov. 13 on everyday technologies in the lives of children with autism as part of the 2019 Distinguished Lecturer Series in the MIND Institute auditorium.
Q&A in urinary incontinence
In honor of Bladder Health Month, UC Davis urogynecologist Amy George shares information about urinary incontinence.
Military partnerships help advance health for all
A training partnership between UC Davis Medical Center and the U.S. Air Force, which began in 1995, has blossomed into a variety of integrated medical residency programs with the military that helps physicians stay prepared for deployment while they provide high-quality patient care here stateside in Sacramento.
Automated quitline referrals help patients give up tobacco
Electronic health record systems that house patient medical histories can also easily link them with telephone counseling services ― or quitlines ― that improve their chances of giving up tobacco.
Radiology professor awarded "Trailblazer" grant for hybrid imaging research
Guobao Wang received a "Trailblazer R21" grant from the National Institute of Biomedical Imaging and Bioengineering to develop a new method combining positron emission tomography (PET) and X-ray computed tomography (CT) scanning.
Car seat safety tips for families using rideshare services, taxis
What do families need to know when using a rideshare service like Uber and Lyft with their children?
Bay Area surgeon and healthcare executive chooses UC Davis for complex cancer surgery
After attempts to see specialists in the Bay Area failed, a San Francisco surgeon sought cancer care at UC Davis Health and is now back doing everything he loves to do.
B. infantis reduces intestinal inflammation in infants
B. infantis, a strain of probiotic bacteria, reduces intestinal inflammation in infants, a new study shows.
UC Davis Health researchers join the search for chlamydia vaccines
Laurel Beckett and Alexander "Sandy" Borowsky are part of a new research effort to develop vaccines for a common sexually transmitted disease.
VIDEO: UC Davis Children's Hospital launches virtual holiday toy drive
UC Davis Children's Hospital will launch its first virtual holiday toy drive this year at https://toydrive.ucdavis.edu.
VIDEO: KVIE shares Emmy honors with UC Davis Health
PBS TV station KVIE presented commemorative Regional Emmy Awards today to UC Davis Health for the documentary "Beyond the Ice Bucket Challenge – Battling ALS," which featured physicians and patients of the UC Davis Multidisciplinary ALS Clinic.
VIDEO: Trick or treating fun, country fair-style, at UC Davis Children's Hospital
Hospitalized children at UC Davis Children's Hospital didn't miss out on trick or treating today. The children's hospital team brought the trick or treating fun to the kids.
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A U.S. News & World Report best hospital in cancer, cardiology and heart surgery, ENT, geriatrics, gynecology, nephrology, neurology & neurosurgery, orthopedics, pulmonology & lung surgery, and urology. »
A U.S. News best children's hospital in neonatology, diabetes & endocrinology, nephrology, *orthopedics, and *urology (*together with Shriners Hospitals for Children – Northern California) »
A U.S. News high-performing hospital in heart bypass surgery, heart failure, lung cancer surgery, colon cancer surgery, knee replacement, gastroenterology & GI surgery, diabetes & endocrinology, abdominal aortic aneurysm repair and COPD. »
UC Davis School of Medicine ranks among nation's best in primary care »
UC Davis School of Medicine ranks among nation's best in research »
Betty Irene Moore School of Nursing ranks among the best in the country for master's-degree nursing programs »
UC Davis Medical Center has received Magnet® recognition, the nation's highest honor for nursing excellence »
"Most Wired" designation »
UC Davis Health recognized with a 4.5-star designation for providing high-quality care to Medicare Advantage patients »
National Cancer Institute "comprehensive" designation
For the ninth consecutive year, UC Davis Medical Center has been recognized as a "Leader in LGBTQ Healthcare Equality" »
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Megan is a destination wedding and engagement photographer based in the midwest. Along with wedding photography, Megan captures personality-driven headshots and portraits for individuals within the acting and modeling communities. Holding a BA in Intercultural Studies, Megan loves to work cross-culturally to celebrate an array of wedding celebrations and customs, as well as highlight the beautiful array of people in the world. Having earned two Fearless Awards, Megan enjoys pushing the limits of what wedding photography can be, and loves to utilize light in dramatic and creative ways to create timeless images for her clients.
Beyond photography, Megan enjoys spending time with her husband and son, traveling, pursuing opportunities to further her photographic knowledge, and sneaking in a round of Call of Duty on the xbox when her guys fall asleep for the night. You'll find her doing all of the above with music playing, and a coffee in hand.