text:
Vinyl (220)
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ABBA ARE BACK! Agnetha, Björn, Benny and Anni-Frid return with: ABBA VOYAGE A revolutionary concert, 40 years in the making, and a brand new studio album Voyage Thursday 2nd September - ABBA, one of the most successful pop groups of all time, have today announced that, for the first time in 40 year...
Vinyl LP 2021-11-05
Voyage Vinyl LP
ABBA ARE BACK!

Agnetha, Björn, Benny and Anni-Frid return with:

ABBA VOYAGE

A revolutionary concert, 40 years in the making,
and a brand new studio album Voyage

Thursday 2nd September - ABBA, one of the most successful pop groups of all time, have today announced that, for the first time in 40 years they are back, with a revolutionary new concert that will see Agnetha, Björn, Benny and Anni-Frid performing digitally with a live 10-piece band, in a purpose-built arena in London from 27th May 2022, and a brand new studio album.

The digital versions of ABBA have been created following weeks and months of motion-capture and performance techniques with the four band members and an 850-strong team from Industrial Light & Magic, the company founded by George Lucas, in what is the company's first foray into music.

Now, an incredible 40 years since their last studio album The Visitors, ABBA have not only recorded two new songs, 'I Still Have Faith In You' and 'Don't Shut Me Down', that will both feature in the concert, but they have recorded and produced an entire new album. Recorded together at Benny's studio Riksmixningsverket in Stockholm, Voyage will be released worldwide on 5th November on Universal Music Group.

ABBA Voyage will open 27th May 2022 at the ABBA Arena, a state-of-the-art 3,000 capacity arena located at Queen Elizabeth Olympic Park in London. Pre-registration for tickets opens at 6pm tonight on abbavoyage.com with tickets on general sale from Tuesday 7th September, see below for more detail.

The ABBA Voyage concert is made with the help of: Producer Svana Gisla (David Bowie Blackstar/Lazarus, Beyoncé and Jay Z for HBO, Springsteen and I), Producer Ludvig Andersson (And Then We Danced, Yung Lean - "In My Head", Mamma Mia! Here We Go Again), Director Baillie Walsh (Flashbacks of a Fool, Being James Bond, Springsteen and I), Co-Executive Producer Johan Renck (Spaceman, David Bowie Blackstar/Lazarus, Chernobyl) and Choreographer Wayne McGregor CBE (The Royal Ballet, Company Wayne McGregor, Paris Opera Ballet).

Svana Gisla, Producer, and Ludvig Andersson, Producer:
"The magic of ABBA and the herculean efforts of this whole magnificent team reaches a long awaited milestone today. To be able to finally share this endeavour with the world is a proud moment for us and we can't wait to welcome you to our arena in East London, a place where we are so happy to be."

Baillie Walsh, Director:
"I watched ABBA win the Eurovision song contest in 1974, and never did I imagine that 47 years later I would be with them on this extraordinary voyage. Life is weird and wonderful sometimes."

Wayne McGregor, Choreographer: "Imagine: growing up in the North of England in the 70's and learning to ballroom, Latin and disco dance to the incredible songs of ABBA. I was 8 and I was totally transported. Fast forward to 2020, being in Sweden and dancing with ABBA - in real life! I was about to be 50 and I was totally transported again. That is the magic of ABBA.
We have shared many creative and joyful adventures with a bold collaborative team to make the impossible possible for ABBA Voyage: technological wizardry, state of the art immersion and entertainment innovation. And still at its searing heart we simply have new songs, new moves, classic songs, classic moves: ABBA is DANCE and always will be. See you on the dancefloor".

Sir Lucian Grainge, Chairman & CEO, Universal Music Group:
"From the very beginning of my career, and having had the privilege to work with them directly for many years since, it's been a tremendous joy to be surrounded by ABBA and their music. Their boundless creativity and timeless melodies makes us want to partner with them on everything they do because we know it will be simply great."

The music video for 'I Still Have Faith In You' has been directed by Shynola.
Guitar slinger
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Gordon Dexter
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2 Vinyl LP
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Själ och hjärta del 3 (Ltd)
Vinyl 10"
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Winnerbäck Lars
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text:
Q: Rewriting Derby DB tables (with FK) via JPA I can fill 2 tables in a DB where the tables have mappings(one table has a FK from he other). The
EclipseLink DataSource show the flush  to the DB has been done ok.
I am trying to rewrite the tables (with same data a second time ) while  the persistence.xml  has
the properties clause as follows :
  <property name="eclipselink.ddl-generation" value="drop-create-tables" />
yet I see no dropping (erase) of the previous tables before the rewriting and therefore get rejected with  the following exception message about  a duplicate key :

"Internal Exception:
  java.sql.SQLIntegrityConstraintViolationException: The statement was
  aborted because it would have caused a duplicate key value in a unique
  or primary key constraint or unique index identified by
  'SQL120206135740510' defined on 'HOST'. "  ( HOST is the table pointed
  to by the FK).

What am I missing in the  persistence.xml   or else that should make the table drop before the rewrite ?
Below see the  persistence.xml   file ( the DB file is called 'test' . The schema is name after the user name (APP in my case) ):
<?xml version="1.0" encoding="UTF-8"?>
<persistence version="2.0" xmlns="http://java.sun.com/xml/ns/persistence" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://java.sun.com/xml/ns/persistence http://java.sun.com/xml/ns/persistence/persistence_2_0.xsd">
        <persistence-unit name="jpa_test">
                <class>Host</class>
                <class>Vm</class>
                <properties>
                        <property name="javax.persistence.jdbc.url" value="jdbc:derby://im6-64s:1527/test;create=true" />
                        <property name="javax.persistence.jdbc.user" value="APP" />
                        <property name="javax.persistence.jdbc.password" value="passw0rd" />
                        <!-- EclipseLink should create the database schema automatically -->
                        <property name="eclipselink.ddl-generation" value="drop-create-tables" />
                        <property name="eclipselink.ddl-generation.output-mode" value="database" />
                </properties>

        </persistence-unit>
</persistence>

A: "drop-create-tables" should be "drop-and-create-tables"

A: Try adding the "eclipselink.logging.level" property with a value of Finest or ALL to see why the drop might not be being executed.

redpajama_set_name: RedPajamaStackExchange


text:
Peter Harder is a Danish linguist and professor of English language at the University of Copenhagen. He is notable as a cofounder of the Danish Functional Linguistics stage of the Copenhagen School in linguistics. He has worked extensively with functional linguistic theories and speech act theory. In Denmark, he is best known amongst the general public for his outspoken criticism against the Danish government's tight regulation of research, which he perceives as a threat to academic freedom.

Publications
(2010) Meaning in Mind and Society: A Functional Contribution to the Social Turn in Cognitive Linguistics. (Cognitive Linguistics Research). Berlin: Mouton de Gruyter. 528 pp.
(2005) Elisabeth Engberg-Pedersen, Michael Fortescue, Peter Harder, Lars Heltoft, Michael Herslund & Lisbeth Falster Jakobsen: Dansk Funktionel Lingvistik - en helhedsforståelse af forholdet mellem sprogstruktur, sprogbrug og kognition. Københavns Universitet & RUC: København.
(2003) The Status of Linguistic Facts: Rethinking the Relation between Cognition, Social Institution and Utterance from a Functional Point of View. Mind and Language 18, 1, 52-76
(2003) Mental spaces: Exactly when do we need them? Cognitive Linguistics 14‑1, 91-96.
(1999) Partial Autonomy. Ontology and Methodology in Cognitive Linguistics, in Theo Janssen and Gisela Redeker (eds.), Cognitive Linguistics: Foundations, Scope and Methodology, Berlin/New York: Mouton de Gruyter, 195-222.
(1999) Function, Cognition and Layered Clause Structure, in Jens Allwood and Peter Gärdenfors (eds.) Cognitive Semantics, Amsterdam/Philadelphia: John Benjamins. 37-66.
 Functional Semantics: A Theory of Meaning, Structure and Tense in English. (Trends in Linguistics: Studies and Monographs 87). Berlin/New York: Mouton de Gruyter. 586 pp.

References

External links
 CV - Peter Harder

Linguists from Denmark
Syntacticians
Academic staff of the University of Copenhagen
Living people
Year of birth missing (living people)

redpajama_set_name: RedPajamaWikipedia


They travel around the world and take in the scenery of Yosemite and other places through highlining and slacklining, with the GGBY Festival in Utah being a yearly tradition.
"We've always done it together and this festival is always something we've gone to together, so we thought it'd be a great place to get married," Jenks said.
With the help of their high-flying and acrobatic friends, they were able to make it happen on Nov. 20, just a day before the festival kicked off. The couple says everyone was safe, even Kimberly's dad, who provided the viral photograph of their wedding.
"There's this photo of him, it's the best photo, it's one of my favorite photos of the wedding. And he had walked me down the aisle, and he made it out there and he said, 'Yes, he'd never done anything like this,'" Weglin said.
The couple wants to raise awareness about the sport and have numerous social media accounts dedicated to their time living the "slack life."
The couple is working on scaling the business so anyone else who wants to get married above a canyon can do so.
"If you live the slack life and all your spare time, and money and energy goes into slacklining, it's just a different kind of vibe," Jenks told FOX40.


As Sr. Technical Product Manager for our Data Foundation, you will be responsible for one or more of Arm Treasure Data's critical big data platform components.
The Data Foundation is comprised of components including: Treasure Data's proprietary multi-tenant data lake, data warehouse, stream ingestion framework, data pipeline orchestration tools, key-value stores, and more. For this role, we are looking for someone with extensive experience with such modern tech stack - who is excited about enabling this foundation for both Treasure Data's CDP, and future IoT world we are preparing for.
Prioritize new work on one or more of our core backend systems. These include our Core API, Petabyte scale storage system, stream data processing, global data ingestion framework, and more.
A technical background, likely within the domain of Big Data Processing and managing SaaS systems at scale. You must be someone who can use our tooling, to quickly become a power user of Treasure Data to properly represent our customers.


text:
French Court Finds 14 People Guilty of Aiding Charlie Hebdo...
Moderna Vaccine Is Highly Protective and Prevents Severe Covid-19, Data...
Chicago Girl Raises $22,000 for Children's Hospital With Friendship Bracelets
As word of her fund-raiser spread, support grew locally and beyond. Both sets of Hayley's grandparents matched the first $1,500 she raised. She got a big boost from Mayor Lori Lightfoot of Chicago, who bought bracelets in the colors of the Chicago White Sox, the Chicago Bears and the Chicago flag. Ms. Lightfoot also shared Hayley's story on social media with the hashtag #ChicagoGoodWorks.
Dec. 16, 2020, 11:50 a.m. ET
"The mayor really started kicking this into high gear," Ms. Orlinsky said.
Gov. J.B. Pritzker of Illinois also bought three Chicago-themed bracelets, according to Ms. Orlinsky. The Chicago White Sox recognized Hayley by naming her one of the team's Heroes Beyond the Diamond. Orders have come in from as far as Hawaii and Italy.
Hayley, who is in second grade and enjoys dancing and acrobatics, makes the bulk of the bracelets herself, looping small, colorful rubber bands over her thumb and index finger repeatedly. She has had help from her family, including her younger sister, Ellie, who sorts the colors, and friends from her summer day camp who pitched in to help her meet her orders.
It takes Hayley about two minutes to make each bracelet, she said. She works on her bed while listening to Taylor Swift and Kelly Clarkson and asking Alexa to tell her knock-knock jokes.
She sells the bracelets for $3 apiece or $5 a pair and has come up with holiday-themed variations, including for Hanukkah and Christmas.
"She would constantly come up with opportunities to upsell people," her mother said with a laugh.
The money from the bracelets has been donated to the hospital's Covid-19 relief fund, which provides personal protective equipment like masks and goggles for staff members and patients' families, according to Tracey McCusker, an associate director of community engagement at the hospital.
"Hayley has been such an inspiration to all of us at Lurie Children's Hospital," Ms. McCusker said on Wednesday. "She definitely has been a shining light through this pandemic, and we can't thank her enough."
In Mali, 'France is paying the price for its own ambiguity,' expert says
Focus – The promise of endless clean energy:...
Biden health officials grilled over state of pandemic
The 52-year-search for a missing girl
German power-hose company Karcher demands not to be...
Encore! – Author Elif Shafak on vaccine tribalism,...

redpajama_set_name: RedPajamaCommonCrawl


text:
Michelle Payne
Payne suspended after positive drug test
BY: Loop Pacific
10:40, June 29, 2017
Payne had tested positive to Phentermine, a banned appetite suppressant, after submitting a urine sample at a regional meeting in Swan Hill in Australia's southern state of Victoria on June 11.
Racing Victoria stewards will conduct an enquiry on Friday into the results, the state authority said in a statement.
"Ms Payne was advised of (the) findings and stood down from riding in races and trackwork by stewards on 23 June 2017," RV said.
Women Jockey
2015 Melbourne Cup Winner
Read more about Payne suspended after positive drug test
Melbourne Cup raises high hopes for Punters and Bookies
BY: Alfred Kaniniba
16:10, October 31, 2016
The Melbourne Cup which has become a big betting bonanza over the years for the professional punter also has its share of 'once a year punters' who throw in a wager just for the fun of it.
However, to the hardened punter it is the ultimate race which must be won at all cost … at least according to the tips that are offered.
But the reality will set in when the race is run and winner is known.
With the Melbourne Cup every contender can win whether it is the favourite or an outsider given they get the chance to make it.
The Melbourne Cup
Read more about Melbourne Cup raises high hopes for Punters and Bookies
Melbourne Cup: First female jockey to win the great race
BY: Julianna Waeda
The $101 outsider, trained by Darren Weir, stormed to the finish line to beat English stayer Max Dynamite, with Australian weight-for-age star Criterion finishing in third place.
The Ballarat-trained stayer is one of the longest priced winners in the 155-year history of the Melbourne Cup.
Payne, who has had a long association with the six-year-old horse, said she laid in bed the night before the race dreaming of winning the Cup.
"It's like a dream come true, this horse is awesome," Payne said after the race.
Prince of Penzance
Read more about Melbourne Cup: First female jockey to win the great race


Great for anyone wanting to resolve the 'age of the earth' controversy biblically and scientifically.
This is two files (329mb and 282mb, both 720x480px MP4 video files) which needs to be downloaded to your computer / tablet / smart phone before you can watch it. The software/program needed to watch the video will normally be already on your device but if necessary free software can be downloaded from the internet and installed.


text:
A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters
Patrick Masson, Florian Nachon, Clarence A. Broomfield, David E. Lenz, Laurent Verdier, Lawrence M. Schopfer, Oksana Lockridge
Wild-type human butyrylcholinesterase (BuChE) has proven to be an efficient bioscavenger for protection against nerve agent toxicity. Human acetylcholinesterase (AChE) has a similar potential. A limitation to their usefulness is that both cholinesterases (ChEs) react stoichiometrically with organophosphosphorus (OP) esters. Because OPs can be regarded as pseudo-substrates for which the dephosphylation rate constant is almost zero, several strategies have been attempted to promote the dephosphylation reaction. Oxime-mediated reactivation of phosphylated ChEs generates a turnover, but it is too slow to make pseudo-catalytic scavengers of pharmacological interest. Alternatively, it was hypothesized that ChEs could be converted into OP hydrolases by using rational site-directed mutagenesis based upon the crystal structure of ChEs. The idea was to introduce a nucleophile into the oxyanion hole, at an appropriate position to promote hydrolysis of the phospho-serine bond via a base catalysis mechanism. Such mutants, if they showed the desired catalytic and pharmacokinetic properties, could be used as catalytic scavengers. The first mutant of human BuChE that was capable of hydrolyzing OPs was G117H. It had a slow rate. Crystallographic study of the G117H mutant showed that hydrolysis likely occurs by activation of a water molecule rather than direct nucleophilic attack by H117. Numerous BuChE mutants were made later, but none of them was better than the G117H mutant at hydrolyzing OPs, with the exception of soman. Soman aged too rapidly to be hydrolyzed by G117H. Hydrolysis was however accomplished with the double mutant G117H/E197Q, which did not age after phosphonylation with soman. Multiple mutations in the active center of human and Bungarus AChE led to enzymes displaying low catalytic activity towards OPs and unwanted kinetic complexities. A new generation of human AChE mutants has been designed with the assistance of molecular modelling and computational methods. According to the putative water-activation mechanism of G117H BChE, a new histidine/aspartate dyad was introduced into the active center of human AChE at the optimum location for hydrolysis of the OP adduct. Additional mutations were made for optimizing activity of the new dyad. It is anticipated that these new mutants will have OP hydrolase activity.
Butyrylcholinesterase
Catalytic bioscavenger
Organophosphorus compound
Dive into the research topics of 'A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters'. Together they form a unique fingerprint.
Cholinesterases Medicine & Life Sciences 100%
Soman Chemical Compounds 90%
Esters Medicine & Life Sciences 84%
Toxic Chemical Compounds 62%
Poisons Medicine & Life Sciences 61%
Acetylcholinesterase Medicine & Life Sciences 61%
Butyrylcholinesterase Medicine & Life Sciences 56%
Hydrolysis Chemical Compounds 51%
Masson, P., Nachon, F., Broomfield, C. A., Lenz, D. E., Verdier, L., Schopfer, L. M., & Lockridge, O. (2008). A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters. Chemico-Biological Interactions, 175(1-3), 273-280. https://doi.org/10.1016/j.cbi.2008.04.005
A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters. / Masson, Patrick; Nachon, Florian; Broomfield, Clarence A. et al.
In: Chemico-Biological Interactions, Vol. 175, No. 1-3, 25.09.2008, p. 273-280.
Masson, P, Nachon, F, Broomfield, CA, Lenz, DE, Verdier, L, Schopfer, LM & Lockridge, O 2008, 'A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters', Chemico-Biological Interactions, vol. 175, no. 1-3, pp. 273-280. https://doi.org/10.1016/j.cbi.2008.04.005
Masson P, Nachon F, Broomfield CA, Lenz DE, Verdier L, Schopfer LM et al. A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters. Chemico-Biological Interactions. 2008 Sep 25;175(1-3):273-280. doi: 10.1016/j.cbi.2008.04.005
Masson, Patrick ; Nachon, Florian ; Broomfield, Clarence A. et al. / A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters. In: Chemico-Biological Interactions. 2008 ; Vol. 175, No. 1-3. pp. 273-280.
@article{c488d7750b5149cc94935c19e725b01a,
title = "A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters",
abstract = "Wild-type human butyrylcholinesterase (BuChE) has proven to be an efficient bioscavenger for protection against nerve agent toxicity. Human acetylcholinesterase (AChE) has a similar potential. A limitation to their usefulness is that both cholinesterases (ChEs) react stoichiometrically with organophosphosphorus (OP) esters. Because OPs can be regarded as pseudo-substrates for which the dephosphylation rate constant is almost zero, several strategies have been attempted to promote the dephosphylation reaction. Oxime-mediated reactivation of phosphylated ChEs generates a turnover, but it is too slow to make pseudo-catalytic scavengers of pharmacological interest. Alternatively, it was hypothesized that ChEs could be converted into OP hydrolases by using rational site-directed mutagenesis based upon the crystal structure of ChEs. The idea was to introduce a nucleophile into the oxyanion hole, at an appropriate position to promote hydrolysis of the phospho-serine bond via a base catalysis mechanism. Such mutants, if they showed the desired catalytic and pharmacokinetic properties, could be used as catalytic scavengers. The first mutant of human BuChE that was capable of hydrolyzing OPs was G117H. It had a slow rate. Crystallographic study of the G117H mutant showed that hydrolysis likely occurs by activation of a water molecule rather than direct nucleophilic attack by H117. Numerous BuChE mutants were made later, but none of them was better than the G117H mutant at hydrolyzing OPs, with the exception of soman. Soman aged too rapidly to be hydrolyzed by G117H. Hydrolysis was however accomplished with the double mutant G117H/E197Q, which did not age after phosphonylation with soman. Multiple mutations in the active center of human and Bungarus AChE led to enzymes displaying low catalytic activity towards OPs and unwanted kinetic complexities. A new generation of human AChE mutants has been designed with the assistance of molecular modelling and computational methods. According to the putative water-activation mechanism of G117H BChE, a new histidine/aspartate dyad was introduced into the active center of human AChE at the optimum location for hydrolysis of the OP adduct. Additional mutations were made for optimizing activity of the new dyad. It is anticipated that these new mutants will have OP hydrolase activity.",
keywords = "Acetylcholinesterase, Butyrylcholinesterase, Catalytic bioscavenger, Organophosphorus compound",
author = "Patrick Masson and Florian Nachon and Broomfield, {Clarence A.} and Lenz, {David E.} and Laurent Verdier and Schopfer, {Lawrence M.} and Oksana Lockridge",
note = "Funding Information: This work was supported by US Army Medical Research and Materiel Command DAMD17-01-2-0036 to OL and DGA (03-CO 010-05/PEA 01.08.07) to PM.",
T1 - A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters
AU - Masson, Patrick
AU - Nachon, Florian
AU - Broomfield, Clarence A.
AU - Lenz, David E.
AU - Verdier, Laurent
N1 - Funding Information: This work was supported by US Army Medical Research and Materiel Command DAMD17-01-2-0036 to OL and DGA (03-CO 010-05/PEA 01.08.07) to PM.
N2 - Wild-type human butyrylcholinesterase (BuChE) has proven to be an efficient bioscavenger for protection against nerve agent toxicity. Human acetylcholinesterase (AChE) has a similar potential. A limitation to their usefulness is that both cholinesterases (ChEs) react stoichiometrically with organophosphosphorus (OP) esters. Because OPs can be regarded as pseudo-substrates for which the dephosphylation rate constant is almost zero, several strategies have been attempted to promote the dephosphylation reaction. Oxime-mediated reactivation of phosphylated ChEs generates a turnover, but it is too slow to make pseudo-catalytic scavengers of pharmacological interest. Alternatively, it was hypothesized that ChEs could be converted into OP hydrolases by using rational site-directed mutagenesis based upon the crystal structure of ChEs. The idea was to introduce a nucleophile into the oxyanion hole, at an appropriate position to promote hydrolysis of the phospho-serine bond via a base catalysis mechanism. Such mutants, if they showed the desired catalytic and pharmacokinetic properties, could be used as catalytic scavengers. The first mutant of human BuChE that was capable of hydrolyzing OPs was G117H. It had a slow rate. Crystallographic study of the G117H mutant showed that hydrolysis likely occurs by activation of a water molecule rather than direct nucleophilic attack by H117. Numerous BuChE mutants were made later, but none of them was better than the G117H mutant at hydrolyzing OPs, with the exception of soman. Soman aged too rapidly to be hydrolyzed by G117H. Hydrolysis was however accomplished with the double mutant G117H/E197Q, which did not age after phosphonylation with soman. Multiple mutations in the active center of human and Bungarus AChE led to enzymes displaying low catalytic activity towards OPs and unwanted kinetic complexities. A new generation of human AChE mutants has been designed with the assistance of molecular modelling and computational methods. According to the putative water-activation mechanism of G117H BChE, a new histidine/aspartate dyad was introduced into the active center of human AChE at the optimum location for hydrolysis of the OP adduct. Additional mutations were made for optimizing activity of the new dyad. It is anticipated that these new mutants will have OP hydrolase activity.
AB - Wild-type human butyrylcholinesterase (BuChE) has proven to be an efficient bioscavenger for protection against nerve agent toxicity. Human acetylcholinesterase (AChE) has a similar potential. A limitation to their usefulness is that both cholinesterases (ChEs) react stoichiometrically with organophosphosphorus (OP) esters. Because OPs can be regarded as pseudo-substrates for which the dephosphylation rate constant is almost zero, several strategies have been attempted to promote the dephosphylation reaction. Oxime-mediated reactivation of phosphylated ChEs generates a turnover, but it is too slow to make pseudo-catalytic scavengers of pharmacological interest. Alternatively, it was hypothesized that ChEs could be converted into OP hydrolases by using rational site-directed mutagenesis based upon the crystal structure of ChEs. The idea was to introduce a nucleophile into the oxyanion hole, at an appropriate position to promote hydrolysis of the phospho-serine bond via a base catalysis mechanism. Such mutants, if they showed the desired catalytic and pharmacokinetic properties, could be used as catalytic scavengers. The first mutant of human BuChE that was capable of hydrolyzing OPs was G117H. It had a slow rate. Crystallographic study of the G117H mutant showed that hydrolysis likely occurs by activation of a water molecule rather than direct nucleophilic attack by H117. Numerous BuChE mutants were made later, but none of them was better than the G117H mutant at hydrolyzing OPs, with the exception of soman. Soman aged too rapidly to be hydrolyzed by G117H. Hydrolysis was however accomplished with the double mutant G117H/E197Q, which did not age after phosphonylation with soman. Multiple mutations in the active center of human and Bungarus AChE led to enzymes displaying low catalytic activity towards OPs and unwanted kinetic complexities. A new generation of human AChE mutants has been designed with the assistance of molecular modelling and computational methods. According to the putative water-activation mechanism of G117H BChE, a new histidine/aspartate dyad was introduced into the active center of human AChE at the optimum location for hydrolysis of the OP adduct. Additional mutations were made for optimizing activity of the new dyad. It is anticipated that these new mutants will have OP hydrolase activity.
KW - Acetylcholinesterase
KW - Butyrylcholinesterase
KW - Catalytic bioscavenger
KW - Organophosphorus compound


Thank you for your interest in Mather LifeWays Institute on Aging. Please fill out the form below and we'll be in touch soon. You can also call (888) 722.6468 to speak with someone directly.
Yes! I'd like to receive e-mails about the latest research from Mather LifeWays Institute on Aging.


If you're something of a Netflix aficionado and you're in the mood for a career change, this might just be the perfect job for you: the streaming giant is looking to hire professional binge-watchers.
But, before your get your hopes up, there is a big catch: you have to be fluent in Japanese - because you'll mostly be watching and reviewing Japanese-language anime TV shows and films. Well, at least that dramatically cuts down the competition for the position.
If you live in California, or are prepared to move, we'd recommend getting in your CV early because these positions aren't going to stay open for long.


Marks Cajun BBQ Sauce | Cooking Wine And Travel - The site where Foodies Unite!
This is the sauce that we used to win the annual Ribfest in Gatlinburg, Tennessee. The secret to this sauce is burning 1/2 of the onions, and I do mean burn them to a crisp until the onions turn into charcoal. When added to the sauce, the burnt onions introduce a nice smoky flavor and an interesting crunch to the bite.
In large saucepan, heat tomato catsup with molasses, Tabasco, cayenne pepper, mustard, salt, pepper, and lemon juice.
Pre-heat pan on medium to high heat and add 2 tablespoons olive oil. Brown 1/2 of the onions (about 3-5 minutes), then add garlic and crushed red pepper. Then deglaze with wine and cook until reduced (about 3 minutes). Add to sauce.
In the same pan, turn heat to high and add remaining olive oil. Add remaining onion and cook until blackened (it must be as black and hard as charcoal). Add to the sauce.
Cook until thickened and let simmer for at least 1 hour.


text:
All Hat and All Hate
by The Prowler
MOVEON.ORG'S LONGHORNS
The new anti-Bush 527 "Texans for Truth" turns out to be nothing more than an extension of the larger 527 anti-Bush, George Soros– and organized labor-financed, MoveOn.org.
According to a DNC fundraiser, the Texas group approached the party for possible financing about a month ago, but was turned away. "We didn't have the money, and it would have looked terrible to do that anyway," says the fundraiser, who added that the party steered the group to MoveOn.org. So much for that ban on coordination.
MoveOn.org offered to give the Texas group free advertising, as well as assistance in fundraising, but according to a MoveOn.org coordinator with the AFL-CIO, the group actually funneled more than $75,000 of its own money into accounts controlled by the Texas organization.
As well, MoveOn.org media advisers assisted the group in putting together its website and the commercial that is now running in some swing states.
SHOWS OF BIAS
The Boston Globe claimed that when it published its story on Wednesday that essentially plowed old ground about President Bush's National Guard service, it was merely a coincidence that its sister publication, the New York Times, as well as CBS News and several anti-Bush groups, were mounting a mud-slinging campaign on the same topic on the same day.
That may be true.
But the facts remain that several news organizations continue to sit on stories that are more recent than the events of 1971, and would prove extremely damaging to the Kerry campaign.
"I don't know why they aren't running the stories," says an editor at one of the news organizations. "The stories are in the can and have been combed through by our lawyers. It's frustrating."
BEYOND SALVATION
Back in late 2001 and early 2002, Democrats in the House and the Senate played political games with funding proposals for protecting the United States from terrorist attacks. They paid for their gamesmanship by losing seats in both houses in the mid-term elections.
Apparently, they haven't learned their lesson.
With both the House and the Senate considering funding for Homeland Security issues right now, Democrats in the Senate are attempting to use the funding requests to "Christmas Tree" all kinds of pork spending onto those critical budget proposals.


Accra, June 16, GNA - The Speaker of Parliament, Mr Peter Ala Adjetey on Wednesday said peace was imperative to Africa's development. He made the remark when Mr Ato Cham Ugala, Ethiopian Ambassador to Ghana, called on him in his office to brief him on the conflict between Ethiopia and Eritrea over a parcel of land along the boundary between the two countries.
The Ambassador was accompanied by, Ms Atsede Kidanu, Minister Consular at the Ethiopian Embassy in Ghana. Mr Ala Adjetey said, "armed conflict is not desirable - we are far behind in our developmental effort as a continent and we need peace to develop".
He noted that though Africa was potentially wealthy, its peoples were so impoverished that "we cannot afford to engage in violent conflicts and keep wasting our meagre gains to resolve them". He urged the Ethiopian Ambassador to impress upon his government to exercise restraint in the way they handled the land conflict between them and Eritrea, saying that, whatever resulted from the work of the Boundary Commission set up to look into the matter, it would definitely demand some compromise on the part of both parties.
Mr Osei Kyei-Mensah Bonsu, the Majority Chief Whip and member of the ECOWAS Parliament, noted the need for restraint on the part of the Ethiopian Government in the matter, adding, it was vital to the peace of the area and Africa as a whole.
He alluded to the Nigerian-Cameroonian conflict over the Bakassie Peninsular, saying that, beyond the ruling of the World Court, the two countries resorted to dialogue and showed that dialogue was the best means to a lasting solution.
Mr Ugala noted that though the parcel of land in contention was not as big as can be, "our position is that justice must be done to ensure that the land is given to the rightful owners."


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Pertti Jaakko Neuvonen, född 25 augusti 1943 i Kirvus, död 14 maj 2020 i Helsingfors, var en finländsk läkare.

Neuvonen blev medicine och kirurgie doktor 1971. Han verkade sedan 1992 som professor i klinisk farmakologi vid Helsingfors universitet och som överläkare i klinisk farmakologi vid Helsingfors universitetscentralsjukhus (HUCS). Han var 1988–1992 professor i farmakologi vid Åbo universitet. År 1998 utnämndes han till ledamot av Finska Vetenskapsakademien.

Neuvonens vetenskapliga arbeten rör klinisk farmakologi, farmakokinetik, toxikologi och läkemedelsinteraktioner.

Källor

Uppslagsverk

Noter

Avlidna 2020
Personer från Karelen
Personer verksamma vid Åbo universitet
Män
Födda 1943
Finländska professorer i medicin
Finländska farmakologer
Ledamöter av Finska Vetenskapsakademien
Finländska forskare under 1900-talet


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Two floors of Western & Work Apparel. Wrangler, Roper, Carhartt, Redwing Boots & More. Check us out for Sales & Deals.
Two floors of Western & Work Apparel. We carry brand names like Carhartt - for men & woman, Wrangler, RedWing Boots, Montana Silversmiths Jewelry, Cowboy Hats and Boots as well as Professional's Choice Horse Gear and so much more.
If you've been to or used Annie Oakley's & the Working Man, leave a review.


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How to leverage sports sponsorship with social media: The example of adidas' all in or nothing campaign and Twitter during the FIFA World Cup 2014 (Part 2: Good content is not for free)
October 1, 2015 BrandBa.se
Written by Reiner Joachim Schleich
Part 2: Good content is not for free
When adding social media to the marketing mix, Aminelli and Villanueva (2011) state that SMM and traditional marketing are competing against each other by fighting for budget, attention, time and engagement. Therefore, SMM is not for free because it requires skilled staff and creativity. After examining the overall context and statistics of the campaign, it will be analysed how adidas' Twitter activities contributed to overall success of the sponsorship.
Online and offline investments
Analysing the investments made in SMM and traditional marketing helps to understand the relation between these two elements in adidas' campaign. While the online investment is estimated to account for 68mUSD, the traditional marketing activities consists mainly of sponsorship which can be defined as,
'an investment in cash of kind in an event, team or person, in order to secure sponsors' access to the commercial potential associated with that event, team or person' (Fahey, Farelly & Quester, 2004),
and add up to more or less 130.5mUSD (Buchner, 2014). However, it must be considered that the traditional marketing investment is distributed over a period of four years. As a consequence, sponsorship has become a highly strategic tool and long-term investment within a company's communication mix (Kapferer, 2012).
Social media activities, however, are concentrated in a short distance to the actual tournament itself, which might justify the significantly lower amount of money invested in SMM in relation to sponsorship. Nevertheless, researchers expect that companies will allocate significant resources (Weinberg & Pehlivan, 2011) to SMM in order to facilitate interactions.
Experience and brand promise
adidas has a long track record in sponsorship. However, due to rising sponsoring costs and external competition, the pressure to capitalize on SMM (Tiago & Veríssimo, 2014) and to deliver authentic and relevant content increases. As official sponsor of the FIFA World Cup 2014, adidas has access to exclusive locations and behind-the-scenes material, such as FIFA events, stadiums and fan zones. When investing in sponsorship, a company needs to leverage and activate its investment in order to exploit the commercial potential around the event. This might require further investments, adding up almost to the same amount of money that has been necessary to pay the sponsorship (Houston-Waesch, 2014). Ramsden explains, that to
'unlock your potential and get the most out of the biggest event in sport is to be 'all in' […] we present a unique, fresh and authentic view of the World Cup that only adidas can deliver' (adidas, 2014a).
When analysing the campaign, you can notice that adidas leverages very well its exclusive access to the event and it seem to have met the taste of the global football community. As mentioned before, adidas launched its first world cup related video in May 2014. Only a few days later, adidas France captured the all in or nothing mind-set in a very symbolic manner. It destroyed France's team bus from the previous World Cup, which had become a symbol of disastrous failure. This action illustrated a new start, representing zero compromise towards the 2014 World Cup. adidas France clearly lived the philosophy and demonstrated its support to one of its long-term sponsored teams. This event appealed to the emotions of French football fans and spread even more the word-of-mouth of the campaign. A clear connection to adidas' brand philosophy is made and it was promoted by the media and opinion leaders that attended the event (adidas, 2014b).
An example of innovative communication, first hand content and the creativity demonstrates the official match ball. adidas' Brazuca ball for the FIFA World Cup 2014 was developed over several years including extensive test phases with professional players, trying to develop a high performing product with the best available technology (adidas Group, 2014). By crowdsourcing the name of the ball, adidas succeeded to connect to Brazilian football fans, although their national team is equipped by its competitor Nike.
It is not new that individual player have their own Twitter account, which provides fans with news and insights (Borden, 2014). But by creating a Twitter account for the Brazuca ball, a completely new perspective was added to the World Cup experience. Not only the videos and images, but also the entertaining and informing tweets set a completely new way of communication and interaction. This creative and strategic move by adidas has been rewarded during the World Cup. @Brazuca generated millions of interactions on social media. It allowed adidas to create personalized real-time content, capturing the most emotional moments of the tournament. Tweets of @brazuca included pictures of players with funny facial expressions, comments on goals and match results among others. Ramsden argues:
'[…] real-time communications would be the best way for adidas to win the World Cup. We are so engrained and connected to the sport through our products, players and federations, there is never a moment in football where we are absent and, […], our knowledge and understanding of the game means we are the most engaging brand with football fans' (FIFA, 2014).
A few examples of @brazuca indicate its creativity:
'My first 0-0. It feels weird, like I've been turned away from a club.'
'This is a high pressure situation. I'd be flat without pressure though so I thrive on it.'
'Here I am wearing a disguise so I don't get recognised in Rio. I need to focus now.'
Figure 2 - Brazuca ball wearing sunglasses as disguise on the beach in Brazil
'I dreamt of playing with Messi in the @FIFAWorldCup but the reality was better. He does the impossible. #GoldenBall'
Figure 3 @brazuca – adidas golden ball nominee messi (Twitter, 2014b)
Leo Messi nominated for adidas golden ball award with funny facial expression staring at brazuca ball.
Appropriate channel
Twitter has been the right choice for adidas' @brazuca. It allowed real-time interaction with fans, providing short messages or images that catch up the atmosphere of every single match. The mix of planned, anticipated and reactive content generated almost 920.000 mentions of the #allin hashtag on Twitter (adidas, 2014c). Ramsden summarises @brazuca as follows:
'Brazuca is the only character at the FIFA World Cup part of every game and who will meet every player. There isn't a more comprehensive perspective on the tournament than that of the ball and with @brazuca and other initiatives we can not only give people a unique point of view of the tournament but also a chance to interact with arguably the tournament's most visible and embedded icon' (adidas Global, 2014).
Fans were able to participate and engage with the brand by creating their own content. This could be defined as user-generated content, which means
'content that comes from regular people who voluntarily contribute, data, information, or media that then appears before others in a useful or entertaining way, usually on the web' (Krumm, Davies & Narayanaswami, 2008).
Another colleague explains: 'We're going to bring fans along with us on the World Cup journey and give them access to content and experiences that they've never had before…That's something only we can bring because as a sponsor we have access to teams, players and assets that no one else has' (adidas, 2013).
Barwise and Meehan's (2010) research about how to build top brands summarizes what adidas has done throughout its communication campaign. The authors argue that great brands share four qualities. Adapted to adidas' all in-or-nothing campaign those qualities can be summarised as follows:
1. offers and communicates a clear, relevant customer promise
adidas football's brand promise is clear. Be #allin and give the best you can or you will lose everything. The message is relevant to all participating teams and it also matches the spirit of football fans, officials and sponsors.
2. builds trust by delivering on that promise
adidas uses its experience, relationships and connects emotionally to individual players or teams. It supports them and on their World Cup journey and addresses them in a personalized way (e.g. starting a new era of French football). The brand engages strongly with its stakeholders and inspires them to participate.
3. drives the market by continually improving that promise
As major equipment supplier adidas develops technological advanced products. The company's deep insights help to improve the quality and their commitment for every tournament.
4. seeks further advantage by innovating beyond the familiar
The biggest innovation in the FIFA 2014 World Cup is the @brazuca account, which added unexperienced dimension the whole tournament, by significantly increasing the value for all its participants and stakeholders.
The analysis shows that in order to exploit sponsoring investments, it is necessary to invest money in SMM. The combination of both investments is necessary to offer fans and users relevant and authentic content, which can increase brand engagement. Furthermore, the content should be precisely timed and contain certain degree of emotions. A brand needs to act as a communication facilitator and inspire users to interact via social media. Additionally, the nature of every social media channel with its specific characteristics (e.g. Twitter for real-time content), needs to be considered when planning to interact with consumers. This might require easing some control and taking risks. High brand engagement offers a source for valuable consumer insights.
There are some limitations to this analysis. First, the competitive environment around the all in or nothing campaign was not covered. adidas' main competitor Nike is known for ambush marketing activities around the FIFA World Cup. In fact, Nike used a very similar campaign called #Riskeverything, which also gained significant attention. It needs to be analysed, which campaign has a longer lasting impact on each of the company's brand performance. Second, the analysis is based only on social media analytics. An analysis of other KPI's such as return on investments, brand awareness or customer satisfaction would provide further insights.
adidas all in or nothing campaign is a good example of leveraging traditional marketing with SMM. However, it must be pointed out that investment in social media activities are not without any risks. Dissatisfaction and riots in Brazil before the World Cup have been taken up by the media. Companies have to act carefully when communicating or connecting with local communities in such a tense situation. Nevertheless, the world biggest football brand seems to understand very well how the global football community looks like and how to inspire them to action.
A quote by Herbert Hainer, CEO of the adidas Group, underlines the necessity of combining both, traditional marketing and SMM:
'This World Cup has been an outstanding success for adidas and clearly underlines our position as the world's leading football brand. From having both finalists, the winning team and all three adidas golden award winners to achieving record football sales and being the most talked-about brand in social media, we were able to dominate the tournament on and off the pitch' (adidas, 2014c).
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← Anti-branding: a way to destroy brands? Case of Apple Inc.How to leverage sports sponsorship with social media: The example of adidas' all in or nothing campaign and Twitter during the FIFA World Cup 2014 (Part 1) →


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Draymond Green: "If I didn't win the title, the season was bad. No excuses "
edcwigtoru78 December 15, 2020 Sports in USA No Comments
Golden State heavy forward Draymond Green, no matter what, sees his team as a contender for the 20/21 championship.
"If I didn't win the title, the season was bad. There are no moral victories. No excuse that this is our first season together, or that Clay is out of action. It's not in my nature, "said Green.
Kyrie Irving: "I wish Harden all the best, but we need to focus on our players"
Brooklyn point guard Kyrie Irving has commented on rumors of a possible exchange of James Harden from the Rockets to the Nets.
"We do not control rumors. I wish James Harden all the best, but we must focus on our players.
James is a great player. I want him to be happy and confident in who he is, first of all as a person, and then as a basketball player, "said Irving.
Mark Gasol: "LeBron's advice helps me to adapt to the Lakers faster
Lakers center Mark Gasol shared how Californian leader LeBron James is helping him adapt to his new team.
"I am a new person on the team. He tells me what they are waiting for, what I can add, and what I am doing well. It's great. This speeds up the adaptation process, so I can be useful faster. LeBron easily makes contact, this is a positive moment, "said the Spaniard.
In Sunday's meeting with the Clippers, Gasol has 6 points, 4 rebounds and 5 assists.
Tobias Harris: "The space on the set is the most important thing for me"
Philadelphia forward Tobias Harris has shared his expectations of playing for the team under new head coach Doc Rivers.
"The most important thing for me is the space on the set. So that I had corridors for passages, there were opportunities for throwing.
We all need to get used to the way each teammate plays in order to make life easier for each other on the court. As the season progresses, attacking space should become more and more, it will be easier for us to create opportunities for attack, "- said Harris.
Last season, the 28-year-old averaged 19.6 points, 6.9 rebounds and 3.2 assists per game, shooting 36.7 percent of his threes.
edcwigtoru78 Sports in USA
Draymond Green explained why Milwaukee has problems in the series with Miami
edcwigtoru78


Saskatoon Search and Rescue (SSAR) became a registered charitable organization on March 1, 2015. We are a ground search and rescue team made up of dedicated volunteers who desire to help and assist others in need in our community by giving their time for training, search missions, preventative information and public awareness. We are on call 24 hours a day, 7 days a week, 365 days a year. SSAR's Mission: To locate lost or missing persons and provide support to our community in non-search emergencies under the direction of Saskatoon Emergency Measures Organization, Saskatoon Police Service, Royal Canadian Mounted Police, or other agency of jurisdiction.
36962: Total cash given to the charity for which tax receipts were issued.
10377: Charities don't issue tax receipts when a donor can't be identified or doesn't want one. This category also includes collection boxes.
8283: Income that doesn't fit into other categories, such as sales revenue, interest and investment income, membership fees, etc.
32438: Total amount spent on charitable programs. "Programs" cover all charitable activities the organization carries out on its own.
4204: Total amount spent on management and administration, including board meetings, accounting, rent, office supplies, etc.
131250: Assets not falling under one of the other categories.
4599: Liabilities not falling under one of the other categories.
Saskatoon Search And Rescue Inc.'s headquarters is located at Post Office Box 28077 Westgate, Saskatoon SK, S7M5V8.


We visited the rainforest home of author & photographer Josh Hedge to have a chat about his philosophy and learn more about his approach to living a natural and authentic life.
You have recently branched out from photography and into many forms of creative expression – including becoming an author, and experimenting with sound and painting. Was this a natural progression, and do you have a preferred method of creativity?
Definitely a natural thing; I didn't pressure any of it. I guess my overall preferred method is just doing what feels best at the time. Somedays I'll feel like writing, and that may continue for a week. Other times I'll prefer to play instruments. Then somedays I enjoy doing it all. So it's a definite 'go with the flow' method which I think suits me as a person, as well as my way of creating / expressing!
In your second book 'Flowers for Growth', the first chapter is titled 'Intention & I'. What were your aims and intentions when you began writing?
I wanted to provide a deeper insight into me. With my photo work and majority of my other writing in general it's very much the 'final product' that people get to see and experience – but like all things there is so much more to it than just the end result. So I wanted to share the 'me' behind all of the things I do, which I think is important and helps people connect with my work much more.
Your writing expresses a concern for modern day humanity and our detachment from nature. What advice would you give someone needing to reconnect with our kind and nurturing home, Mother Earth?
You have recently relocated your home a little more inland from the sea. Do your surroundings help you focus and produce creative work? And do you feel a change of energy out here in the rainforest?
It's a change I've always wanted to do, as I've always lived by the sea, and I am absolutely in love with it. There's definitely a sense of something special where I am and its getting the creativity flowing at a much more rapid rate. The peacefulness is almost indescribable, I don't hear any cars, only endless amounts of birds and wildlife. I've just been sitting around a fire most afternoons, super beautiful!
You have an interesting idea on the misconception of being productive and the beauty of simplicity. Can you explain this for us?
I feel like sometimes we think because we're rushing around doing a million things, that it can give us a sense of being 'productive'. Which is fine, but maybe sometimes its best just to sit back and 'be'. I guess in a way it's that old saying of 'quality over quantity', so maybe embracing a lifestyle where we produce more quality experiences that are worth reflecting on, rather than rushing around chaotically.
My favourite section of your book speaks about change. "If there can be so much hate in the world, there can be just as much love. If there can be so much separation, there can be just as much harmony". Do you see a change coming in the world?
Absolutely, I think we all feel it one way or another. Sure, there is still so much greed, violence and hate in the world, but something is happening that's slowly turning that wheel back to love, it's a pretty exciting time to be alive!


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Olympic village may raid contingency fund again
By Olivia Boyd, Olivia Boyd Olivia Boyd2009-05-13T09:46:00+01:00
Announcement expected on athletes' village to assist developer Lend Lease with further funding
The government has declined to comment on reports it is in discussions over releasing further contingency funds to pay for construction of the Olympic village.
Quarterly 2012 budget figures are to be released by the Department for Culture, Media and Sport this afternoon, and ministers are thought to be preparing an announcement on funding for the £1bn athletes' village.
Work proceeding on the Olympic village earlier this year
The government has already allocated £326m from the contingency pot to the village after developer Lend Lease failed to raise the necessary private investment. Any further raid on funds would have to be approved by a committee chaired by UK chancellor Alistair Darling.
In total, £1.2bn of the £2.7bn Olympic back-up fund has so far been allocated.
Building the London 2012 Olympics timeline
Contingency funds of £95m released for Olympic village
Credit crunch means 50% of finance needed has yet to be secured
Government extends athletes' village funding deadline
Construction expected to be under way before agreement is reached with Lend Lease
Housing association set to seal rescue deal on Olympic village
Southern Housing Group has agreed in principle to help Lend Lease on the 2012 project


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Here's What Michael Bastian Wants You to Wear Next Season
Michael Bastian might be taking a season off from the handsome man parade that's also known as his biannual New York runway show, but he's definitely not taking time off from designing really nice clothes that real guys want to wear. If anything, the man should be taking a breather (he is going big in 2016, after all) before his second line launch next year. But when it comes to his namesake collection for this upcoming Fall-Winter, Bastian is staying true to his M.O., which is to say offering up Italian-influenced tailoring for work and play, next-level knitwear, and slim cargo pants that are the reason we're always telling you to wear slim cargo pants. They're clothes literally any man can wear—and look damn impressive in—but don't announce themselves the way an all-over screen printed hoodie might (not a good thing). So here's your first look at what your best-dressed self could be wearing in six months time...
By Matt Sebra
Related Stories for GQMichael BastianNew York Fashion WeekFall


Fritz Scholder, a painter and printmaker who was one-quarter Luiseño, vowed early in his career never to "paint the Indian." Scholder eventually became interested in Native art and culture—particularly that of the New Mexico Pueblo Indians—when he moved to Santa Fe to teach at the newly-established Institute of American Indian Arts. Scholder was inspired by the ideas presented to him by his young Native students, and ultimately decided that he himself needed to tackle the subject. He painted his first Indian during the winter of 1967, and would go on to create hundreds of images of Indians. They were fresh, beautiful, and occasionally controversial. They have become some of his most iconic images.
In 1970, Scholder signed a contract to create a series of lithographs at Albuquerque's Tamarind Institute. He had experimented with lithography in college, and described the process as "laborious and terribly technical." Under the guidance of Tamarind's experienced printers, however, Scholder began to enjoy the lithography process. Scholder was invigorated by what was, to him, a new way to create and present his ideas. His first major project at Tamarind was his "Indians Forever" suite, which was presented in a portfolio containing eight of his best early pieces.
"Buffalo Dancer" is one of the eight images that comprise the "Indians Forever" suite. According to Clinton Adams' "Fritz Scholder Lithographs," the creation of this "blunt and assertive" piece happened rapidly and naturally. Scholder drew the piece quickly and was immediately pleased with it. There was no question of whether or not it would be included in the suite—Scholder and his printmakers were immediately pleased with this striking black-and-white image of a buffalo dancer's face.
This lithograph was produced in one color and completed in January 1971 in an edition of 75. It is featured in both Clinton Adams' Fritz Scholder Lithographs and the Smithsonian Institution's Scholder/Indians. This is # 57 of 75. It is mounted so that the entire image is visible. The lithograph was executed at Tamarind Institute, the renowned lithography workshop in Albuquerque that is affiliated with the University of New Mexico.


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Our contemporary Christian wall art provides the perfect spiritual ambience for your home. Find Christian paintings with your favorite scripture verse from the Bible. You'll recognize quotes from the books of Philippians, Proverbs, John, Romans, Matthew, Mark and many more to inspire you to walk closer to God. Don't worry as we sell custom Christian wall decor which is framed and available in the NIV (New International Version), KJV (King James Version) or any version of God's holy word. Finally we sell Christian art such as paintings to prints and pictures which are perfect Christian gifts for men and women. Bible Art
Bring a sense of spirituality to any space in your home with this textual art print, showcasing scripture from 2 Corinthians 5:7 in scrolling font with an arrow accent below. Crafted from wood, its frame features a brown finish with distressed details for a warm and weathered touch. A brushed white background completes the neutral look, giving this design the versatility to complement most color palettes. Measures 13'' H x 37'' W. Bible Art
Now there were four supports at the four corners of each stand; its supports were part of the stand itself. On the top of the stand there was a circular form half a cubit high, and on the top of the stand its stays and its borders were part of it. He engraved on the plates of its stays and on its borders, cherubim, lions and palm trees, according to the clear space on each, with wreaths all around.read more.
Then to Adam He said, "Because you have listened to the voice of your wife, and have eaten from the tree about which I commanded you, saying, 'You shall not eat from it'; Cursed is the ground because of you; In toil you will eat of it All the days of your life. "Both thorns and thistles it shall grow for you; And you will eat the plants of the field; By the sweat of your face You will eat bread, Till you return to the ground, Because from it you were taken; For you are dust, And to dust you shall return." Goodnews Art
If you're looking for wall art for sale online, Wayfair has several options sure to satisfy the pickiest shopper. We have a myriad of styles of wall art, and if you want to narrow your options to something more specific than your current filter of "Art Subject: Spiritual & Religious", such as finding wall art by brands like East Urban Home or Carpentree just use the filter options. Wayfair is the best place to shop if you're looking for where to buy wall art online. And remember, we offer free shipping on just about every order over $49.00, so buy wall art today and have them shipped free. Bible Verse Christian Image
Now King Solomon sent and brought Hiram from Tyre. He was a widow's son from the tribe of Naphtali, and his father was a man of Tyre, a worker in bronze; and he was filled with wisdom and understanding and skill for doing any work in bronze So he came to King Solomon and performed all his work. He fashioned the two pillars of bronze; eighteen cubits was the height of one pillar, and a line of twelve cubits measured the circumference of both.read more. Bible Art
And when he had taken the scroll, the four living creatures and the twenty-four elders fell down before the Lamb, each holding a harp, and golden bowls full of incense, which are the prayers of the saints. And they sang a new song, saying, "Worthy are you to take the scroll and to open its seals, for you were slain, and by your blood you ransomed people for God from every tribe and language and people and nation, and you have made them a kingdom and priests to our God, and they shall reign on the earth." Then I looked, and I heard around the throne and the living creatures and the elders the voice of many angels, numbering myriads of myriads and thousands of thousands, saying with a loud voice, "Worthy is the Lamb who was slain, to receive power and wealth and wisdom and might and honor and glory and blessing!" ... Bible Verse Christian Image
So he made two doors of olive wood, and he carved on them carvings of cherubim, palm trees, and open flowers, and overlaid them with gold; and he spread the gold on the cherubim and on the palm trees. So also he made for the entrance of the nave four-sided doorposts of olive wood and two doors of cypress wood; the two leaves of the one door turned on pivots, and the two leaves of the other door turned on pivots. He carved on it cherubim, palm trees, and open flowers; and he overlaid them with gold evenly applied on the engraved work.
Deep breath in... and... namaste. Nothing feels better than a morning yoga session! Whether you have a whole room devoted to your practice or you're just taking up a small corner of your bedroom, you'll love having this calming canvas print in your retreat. Showcasing a meditating Buddha with an abstract distressed motif, it offers soothing tones of gray and gold. Just set it on the wall above your mat, light a few flickering pillar candles, and you've got a serene space to hold that tree pose.... Bible Verse Christian Image
"You shall take two onyx stones and engrave on them the names of the sons of Israel, six of their names on the one stone and the names of the remaining six on the other stone, according to their birth. "As a jeweler engraves a signet, you shall engrave the two stones according to the names of the sons of Israel; you shall set them in filigree settings of gold.read more. Goodnews Art
He made 300 shields of beaten gold, using three hundred shekels of gold on each shield, and the king put them in the house of the forest of Lebanon. Moreover, the king made a great throne of ivory and overlaid it with pure gold. There were six steps to the throne and a footstool in gold attached to the throne, and arms on each side of the seat, and two lions standing beside the arms. Twelve lions were standing there on the six steps on the one side and on the other; nothing like it was made for any other kingdom. All King Solomon's drinking vessels were of gold, and all the vessels of the house of the forest of Lebanon were of pure gold; silver was not considered valuable in the days of Solomon. Bible Art


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This Timeline Proves the Saints Have Dealt with More Adversity than Any Other NFL Team this Season
Stephen Chambers, Getty Images
With everything the New Orleans Saints have had to endure this year, it's insane that they're a legitimate playoff contender going into the final week of the regular season.
Whether we're talking unexpected injuries in both the offseason and the regular season, the fact that 4 different quarterbacks have started games, or the external factors of nature including COVID and natural disasters, it's almost like someone is somewhere with a Voodoo doll and a vendetta.
Not only did the Saints have 57 different starters this season (an NFL record) due to injuries and COVID—but off-the-field drama cause the team to miss key players as a result of suspensions as well.
When NFL historians look back on the 2021 NFL season and see that the Saints were going into their last regular-season game with a shot to make the playoffs, it will truly be puzzling when they look at the timeline of setbacks that plagued the Black & Gold throughout the year.
Remember when our biggest concern going into the season was whether or not Jameis Winston would pan out as Drew Brees' successor at starting QB? How about when we hoped that WR Michael Thomas would be rehabbed in time to be back on the field "by Week 6 at the latest" after a late off-season surgery due to miscommunication?
Even the biggest Saints fan will be taken aback by seeing an actual timeline of these trials and tribulations, and Boot Krewe Media shared that exact graphic that posed the question "Has anyone dealt with more sh*t than the Saints this year?"
Literally, every week the Saints were facing a new challenge (and usually fielding an all-new team) but no matter how much the odds seemed to be stacked up against them, New Orleans battled week in and week out, taking out powerhouse teams like the Packers, the Patriots, and the Bucs (twice).
However the season wraps up, this is one that should be remembered forever—not to mention, one that should have Sean Payton in "Coach of the Year" discussions.
Dallas Cowboys v New Orleans Saints
Jonathan Bachman, Getty Images
But we all know the NFL won't recognize that anytime soon.
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Filed Under: new orleans saints, sean payton
Categories: National Sports, State Sports


Hi. Thanks a lot for these rosters, been playing for 9 seasons now with Seattle, which I edited in to replace San Jose. A quick question, if you don't mind. I've noticed that now as the drafts have become thoroughly populated with generated players, the level of talent has become somewhat more lackluster. Is this a continuing trend, or will the talent level bounce back as the big stars start retiring and coming back as regens? Or are the regens not a 'thing' anymore? Anyway, thanks in advance for your response and sorries if this has been asked already. And once more, thanks for the amazing work you've put in!
The structure of the Danish has just been changed after a few bankruptcies, are there any that can change that to the right structure?
I'm updating all the clubs so I would be happy if some could help with the structure.
My DB doesn't have a lot of re-gens until after the current crop of NHL superstars retire, if that is the type of talent you are talking about. EHM in general is a little weak at creating very deep drafts, so I try to front load this DB a bit. I also don't keep retired players/staff in the DB to save space and reduce weird activity like random un-retirements. The prospect generator helps a for sure and I am experimenting with baking in a few pools of draft ready talent into the DB from the generator. I will probably have that work done over the summer for v4 next season.
I have someone currently updating that league, will look into this. I may be able to update the structure myself. Will look into for a future update.
- Re-added "DEBUG_MODE" to extra_config, this was inadvertently removed during troubleshooting, this should re-enable some small details back into the game, thanks The Feckless Puck and Archi!
- Added several potential future top picks for later NHL Entry Drafts (up to 2023) - thanks MasterMatt25!
- Updated player histories for Mississauga Steelheads, Niagara IceDogs, North Bay Battalion, Oshawa Generals, Ottawa 67's, Owen Sound Attack, Peterborough Petes, Rimouski Oceanics, Rouyn-Noranda, Saginaw Spirit, Saint John Sea Dogs, Sarnia Sting, Sault Ste. Marie Greyhounds, Shawinigan Cataractes, Sherbrooke Phoenix, Sudbury Wolves, Victoriaville Tigres and Windsor Spitfires - thanks Trajan!
- Added several trades, still have to review trade deadline media notes for all three Major Junior leagues.
- All clubs in Tipsport, Chance, 2.Liga, Czeske Krajske and DHL Junior league fully updated - HUGE thanks to Matee!
- All clubs in Liiga updated - thanks ArZka!
- Updated several Liiga-Mestis/Suomi-Sarja affiliations - thanks tomppa169!
- Updated all players/staff in DEL2 - thanks ppaalloo!
- Added/updated signing deadline dates for all Slovakian/Swedish human-playable clubs - thanks ppaalloo!
Next update will be after the NHL trade deadline, unless something super major happens (let's hope so!) Likely between 2/26-2/28.
Hi! Great work as always. You have filled the TBL void with aplomb.
Just one small niggle I would like to point out -- Blake Wheeler is still coded as a power forward rather than as a playmaker (20 deflections and 17 wrist shot rather than 20 passing and 19 anticipation), when he has not played like a power forward for a number of years.
Thanks, I love this kind of feedback, I don't get to watch Wheeler a lot so I will make these changes!
Hello, just found your rosters while waiting for new TBL rosters. I've done NHL 40 project previously on BK's rosters,then on old TBL 10.3, do you think it's possible to use your db and do you mind if I do that? Keep up the good work I've read every post here and the community is very lucky to have such a devoted and hard-working person.
Of course as long as you provide credit I'm fine with that!
I need some help with rebuilding some league structures, if anyone has some time to help make some leagues human-playable again PM or reach out to me on Steam, also my email has been posted a few times in this thread!
I can provide the UK structures if you like.
Favourite Team: Blackhawks, Sharks, Finns, EK65.
Hopefully I can send you something this weekend. There's one minor error I need to fix and work is too busy during the week before then.
This is a big update, we are almost done updating all of Europe! Very proud of this release and THANK YOU for all the support and help I've been receiving! My focus for the month of March is to complete the overhauls of NHL/AHL/ECHL clubs, then shift to completing overhauls of Canadian Major Junior clubs.
- Reset reputation scores across entire DB, thanks Archi for including that mass-edit feature in the new Editor!
- Added more several potential future top picks for later NHL Entry Drafts (up to 2023) - thanks MasterMatt25!
- Updated all African nationality players + staff - thanks Matee!
- Updated names of several clubs in EBYSL and EBSL -- thanks Dani9!
- Updated and added players/staff for EBEL - thanks ppaalloo!
- EBYSL has a new 15 club league structure and schedule - thanks Dani9, credit to BKarchitect!
- EIHL updated -- thanks ppaalloo!
- Updated players/staff for Ontario Hockey League - thanks Matee!
- Updated all Central American country nationality players + staff - thanks Matee!
- Updated several club/competition names -- thanks Dani9!
- Fixed Czech Chance Liga schedule and league structure, playoffs should now be working -- thanks rhames, credit to BKarchitect!
- Updated club rivals for Czech Tipsport - thanks rhames!
- Updated all Danish country nationality players + staff - thanks hons_85!
- Added player records for Danish clubs - thanks hons_85!
- Added career histories for Danish players - thanks hons_85!
- Updated all players/staff for French Synerglace Ligue Magnus -- thanks ppaalloo!
- Added French Synerglace Ligue Magnus and National League 1 as human playable again - credit to BKarchitect for his league structure and logos!
- Updated all Hungarian players/staff -- thanks Mattee!
- Updated several club names -- thanks Dani9!
- Updated all staff with Kazakhstan, Uzbekistan, Kyrgystan, Tajikistan, Azerbaijan and Turkmenistan nationalities -- thanks Matee!
- Updated all Netherlands players/staff -- thanks Matee!
- Updated all Oceania/Asia nationality players + staff - thanks Matee!
- Updated all Romanian players/staff -- thanks Mattee!
- Tipsport structure updated with working relegation and accurate schedule! - thanks Named!
- Updated player transactions and added some new ones -- thanks ppaalloo!
- Updated all players/staff of Spanish nationality -- thanks Matee!
- Removed redundant Swiss Cup (Arosa Challenge Cup) - thanks Dani9!
- Updated and added players/staff for Swiss National League (NLA) - thanks ppaalloo!
- Removed several duplicate players -- thanks bfq_8!
Andrew Nielsen and Tobias Lindberg should be in different clubs - Calgary and Vegas respectively if I remember correct. One 42 year old free agent should be retired and there are still Sedin brothers in Vancouver even though they retired.
Btw I want to say that your rosters are the best I've worked on. Very good Balanced rosters for NHL if it comes to CA/PA evaluation. Considering All the limitations that come with negative potentials for future generated players the evaluation seems really fair. Thank you for All that work you did!
First and foremost: Big Thank You to xECK29x and all the guys who work on this roster! Great job, guys!
my question is why you decided to use translit?
Ukranian Hockey League is a legitimate name, its on the logo (http://uhl.ua/).
using translit it's either "Ukrainska Khokeyna Liha", "Ukrayinska Khokeyna Liha" or "Ukrainska Hokeyna Liha"
same with "Moskva" and "Oblast". Moscow is good, and adding word "Oblast" to the name is absolutely unnecessary.
also there is english version of KHL official site (https://en.khl.ru/).
all these are just my suggestions, though.
@Buho - We almost exclusively use Eliteprospects for club long and short names, this makes import work easier for things like career history updates. However I am happy to make any and all adjustments especially at the request of fans of those leagues/clubs. I will make the changes you suggested, as an American sometimes I am unsure what to use but I don't want to over-Americanize the database, I'd like it to have as much appropriate local accuracy and culture as I can add.
Hey, I've started filling rosters of the Western States Hockey League for my own. If you want I can share all the players I created (with an excel sheet) with you can so you can import them into your database. I also planned filling rosters of many Junior A leagues in Canada later on.
This is where the Synonym data in the Editor comes into play. If you go to the 'Synonym' sub-folder in the Editor installation folder, you'll find a text file entitled "club.txt". You can add alternative spellings in this file which will allow the Editor to match the EliteProspects spelling contained in a spreadsheet against the native spelling in the database. You just list each alternative spelling on a new line in the file with commas separating each spelling. You should check whether any existing spellings/synonyms already exist for the team in question in the file - if they do then you should just add your spellings to the existing line. The same thing applies to league/competition names, first names and second names. I got fed up having to make the same corrections to my player career history spreadsheets every year (e.g. changing Evegny Malkin to Evegeni Malkin) - so I created the files to make/match up the changes for me.
If you do make use of the synonym file then please do post any additions you make to the Editor thread. I will then include these in the default synonym files which come with the Editor.
Would be great! Reach out to me on Steam or email me, xeck29x (at) gmail.com, will give you full credit of course!