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Home Sports Jose Fernandez: Bigger Than Baseball
Jose Fernandez: Bigger Than Baseball
Miami Marlins second baseman Dee Gordon wears a T-shirt reading RIP in honor of pitcher Jose Fernandez during batting practice before a baseball game against the New York Mets, Monday, Sept. 26, 2016, in Miami. Fernandez was killed in a boating accident early Sunday. (AP Photo/Lynne Sladky)
By Nicholas Destefano
Tragedy is not a term accustomed so commonly nor easily. Major League Baseball infrequently refers to displays of tragedy as the game of baseball is filled with excitement and ambition. An ordinary Saturday evening in Southern Florida venue the hometown Miami Marlin's baseball team as the players encountered the streets of Miami. Pitching the next day in his final game of the season against the New York Mets, Marlins pitcher Jose Fernandez made a drastic decision to take a cruise on his 30-foot fishing boat outside the Miami Harbor late that night, exorbitantly later crashing into a nearby jetty along with his two friends. Jose Fernandez's death early morning, September 25th at about 3:00 a.m., redefines the meaning of the word tragedy.
Teammates Giancarlo Stanton, Christian Yelich and Marcell Ozuna convinced the star pitcher the night of his death not to go out on his boat because of choppy waters. Outfielder Giancarlo Stanton expressed Fernandez was stressed and wanted to burn off some steam, insisting he wanted to take his boat out. "Don't go out, Ozuna told the newspapers. Everybody knew he was crazy about that boat and loved being out on the water. I told him I couldn't go out that night because I had the kids and my wife waiting for me."[1] Fernandez vowed for some of his teammates to attend as well, but no one pursued and he continued on his nightly journey. Giancarlo Stanton that morning waited at the Marlins ball park in the same spot as he always did for Jose to arrive at the stadium. When he received news that morning of his beloved friend's death, Stanton convincingly thought it was just a ghastly nightmare and everything would go back to normal. Ultimately, Giancarlo had to accept reality and that Jose would never triumph his way to the park again.
Jose Fernandez was just 24 years old and on the verge of becoming an electrifying pitcher with great talent at such a young age. The Miami Marlins drafted Fernandez the 14th overall pick of the 2011 MLB draft and instantly became a sensation for the organization. He won the 2013 NL Rookie of the Year award and finished third in the CY voting at the age of 21[2]. This season, Jose has certified himself as the ace pitcher of the Marlins and again in CY contention with a 16-8 record, 2.86 ERA and over 250 strikeouts with astonishing performances throughout the season. Entering free agency in the upcoming offseason, Fernandez was ensured to sign a record breaking contract.
Jose Fernandez was not just an exceptional baseball player, but an icon both on and off the field impacting the attention of many fans and supporters. Jose played the game of baseball distinctively more creative than the other players around him with his given stature, techniques and velocity. His every movement was passionate, charismatic, embracing the game with emotion and serenity as he stepped foot on the mound. Jose leverage an entire community to join together in conformity to support to Marlin organization and all Miami fans. "When I think about Jose, I see such a little boy. The way he played, there was joy with him."[3] Manager Don Mattingly exemplifies his star pitcher as he faintly gets the epical words out in a news conference. Jose's love for the game and competition was resembled in every play. He honored his family before every scheduled appearance, especially his mother and grandmother, with a signal of praise. On Jose's fourth attempt departing from Cuba, his mother fell off the boat going to Mexico and the 15-year-old Jose dived in the treacherous waters and saved his beloved mother who he continued to admire[4]. Jose's passion and amorousness for the baseball was bigger than his performances.
The world of baseball was heartbroken the day news let out of the passing of Jose Fernandez. The Miami Marlins cancelled the game on Sunday in mourn of their dear friend. Teams around the league represented the young Marlins star with moments of silence, personifying of Fernandez #16 jerseys and prayer. On Monday, the Miami Marlins manifested a pregame ceremony in remembrance of the imperative Jose Fernandez. With the number "16" painted on the pitcher's mound, the Marlins baseball team met together to pay their respects to Jose while the sobbing crowd sang "Take Me Out to the Ballgame." Each player on the Marlins wore #16 and the uniform number was retired by the Marlins organization at the end of the night. Fans, friends, family members of Jose vigorously attended the game with a sense of beatification toward Fernandez; none other than his pregnant girlfriend who is expecting a girl in a few months. Jose Fernandez was bigger than baseball, a character who embellished the game and kids of all ages want to play like him. Number "16" left a legacy to inspire people to play with high emotion and intensity, to play every game like it's your last. Jose Fernandez strived to be the best ball player, practicing and training more impetuously to be successful. Tragedy is appropriate to illustrate the calamitous life events of Jose Fernandez.
[1] Marlins after Fernandez Tragedy: Boat-Driving Doubt, Baby Heartbreak: Mike Puma: http://nypost.com/2016/09/27/marlins-after-fernandez-tragedy-boat-driving-doubt-baby-heartbreak/
[2] Jose Fernandez's Story: From Saving Mom's Life to Electric Fastballs: Joel Sherman: http://nypost.com/2016/09/25/jose-fernandezs-story-from-saving-moms-life-to-electric-fastballs/
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Lithium is an alkali metal, and like all the other alkali metals, it reacts spontaneously with water, liberating hydrogen gas. The farther down you go in the periodic table, the more reactive the alkali metals become, and as the uppermost one lithium is the least reactive. But it's still a fairly vigorous reaction, and lithium can catch fire spontaneously on a humid day. Lithium is amazingly light, only half the density of water. It would be a great metal for making airplanes out of if it weren't so soft and didn't explode on rainy days. Instead it's used in high-quality batteries and as a medication for mood disorders, because dissolved as lithium ions, it moderates nerve impulses in a way that, for poorly understood reasons, moderates mood swings (see the pills below for more on this).
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Elements Popular in Collections
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Samples with Rotatable Images
Samples with High Resolution Spin Movies
Samples with Stories
Long-life AA battery.
Initially only used in fancy camera batteries, lithium is now available in AA and 9V batteries for use in things like smoke detectors and digital cameras. They are more expensive than regular batteries, but last a lot longer which makes the cost per unit of energy competitive. They also have a very long shelf life compared to other batteries so they do well in emergency flashlights and the like.
Source: Radio Shack
Acquired: 7 August, 2002
Lithium oxide crystals.
If you had some thin lithium foil what would you do with it? I thought that maybe I could melt it into a lump, if I bathed the crucible in helium from a small balloon-filling tank (to prevent rapid oxidation) as I heated it from below. I was wrong.
Even with the helium shield gas, the lithium ignited almost immediately, and then proceeded to burn in much the same way lump magnesium does, only much faster (especially after I turned off the helium). This probably means I wasn't getting enough helium around the crucible, and some moist air was working its way in. Or maybe my helium, which just came from a disposable balloon filling tank, contained an oxygen impurity, which is not at all unlikely. Another possibility is that there was chemical contamination from the battery that permitted combustion.
(After seeing this, reader Walt Zarnoch sent the following: "I just read your page about melting lithium. You jarred my memory when you were talking about the possibility of oxygen impurities in the gas. I have heard that some of the suppliers of helium intended for store kits actually add oxygen intentionally, in small quantity, to the gas so that kids like me don't suffocate when inhaling helium from a balloon." So, that explains that. These days I have a large tank of argon for these purposes.)
I decided to change plans and just let a bigger piece of it (folded up tightly into a lump) burn itself out in the crucible. It lit instantly with a propane torch and burned quite dramatically, and very, very hotly. It actually cracked the tiny thimble-sized ceramic crucible I had it in. (Mind you, this is (was) a high-temperature ceramic crucible intended for burning and melting things in. It's not supposed to crack just because you make it hot.)
The explanation for this was kindly provided by reader Yehoshua Sivan from Israel, who wrote as follows:
About 27 years ago I thought I would melt lithium in a ceramic crucible, and then suck it up into a glass tube (using a propipet, not my mouth!), to preserve a specimen, as I had already done with sodium and potassium [incidentally the specimens prepared then are as shiny today as when prepared originally; the oxide at the open ends of the tube acts as a plug preventing further oxidation, and the tube is kept in paraffin oil anyway]. Well, the lithium ignited, I beat a hasty retreat and watched the reaction through the crack in the door, and after some kind of explosion a piece of burning lithium fell on the brand new asbestos table (yes, they were still fitting asbestos tables then), where it also exploded, leaving a hole in the surface. I subsequently explained to my colleagues that now the table really looked as if it belonged to a chemistry laboratory.
I thought then, and I see no reason to think otherwise now, that this was a simple oxidation-reduction reaction, in which the lithium "steals" the oxygen from the silicon dioxide and other oxides in the ceramic (and in the asbestos). The reaction is analogous to the well known magnesium-sand reaction, or to the formation of a black silicon mark on test-tubes in which Mg or Na has been burned (e.g. in the classic magnesium burning in steam reaction, or when I burn sodium in a flow of chlorine).
Sounds very familiar. This being a small world, I suppose it should come as no surprise to anyone that Yehoshua has been proof-reading the Hebrew translation of Uncle Tungsten, whose author Oliver Sacks recently came to visit me, and that Sacks' mother was Yehoshua's mother's family doctor. Nope, doesn't surprise me at all.
Yehoshua also pointed out two interesting articles about the great lithium fire of 1998, which occurred at a chemical waste dump in Israel: Article 1, article 2.
Acquired: 12 August, 2002
Lumps.
The irritating thing about storing lithium is that it floats on the oil. That means unless you completely fill the jar, there's always a bit poking out above the oil, and that part starts oxidizing. The effect of which you can clearly see in the picture of this sample.
Click the source link for an interesting story about where this sample came from.
I chose this sample to represent its element in my Photographic Periodic Table Poster. The sample photograph includes text exactly as it appears in the poster, which you are encouraged to buy a copy of.
Source: Tryggvi Emilsson and Timothy Brumleve
Contributor: Tryggvi Emilsson and Timothy Brumleve
Acquired: 6 September, 2002
Text Updated: 4 May, 2007
Pills for mood disorders.
Lithium, just plain lithium (as a salt), has been used for decades as a treatment for manic-depressive disorders and other illnesses that effect the affect. There aren't very many elements that are used as medical treatments (other than as nutritional supplements like iron and calcium). Two examples, with links to articles about their uses, are carbon (legitimate) and phosphorus (historical). Although the pills actually contain a lithium salt (lithium carbonate), it is the simple lithium that does the work. One theory is that because it is in the same column in the periodic table as sodium and potassium (all are alkali metals), it is able to stand in for them in their important role in the transmission of nerve impulses. By modifying in some poorly understood way how nerve signals propagate, lithium just happens to calm mood swings.
An element is certainly a rather blunt instrument compared to, say, a carefully crafted organic molecule, but if it does the job, who's to complain?
The source of this sample, Raph Levien, is as fascinated as I am by the fact that plain lithium is still a popular mood-stabilizing medication. A family member of his switched from lithium to a different medication around the same time he discovered my Periodic Table, so naturally he thought of contributing the leftover pills to the table. (There's a lesson here for anyone reading this who has a spare element handy....)
I was a bit surprised at how many pills he sent, especially after reading that as few as 20 can be fatal. (The toxic dose is very close to the therapeutic dose, and since these pills are given to people who are, well, depressed, you can imagine that some care has to be take to avoid suicide attempts!) I've sealed a sub-lethal dose in a plastic display container and locked the rest up for safekeeping.
Raph also supplied the following interesting URLs about lithium as a medication:
jama.ama-assn.org/issues/v281n24/ffull/jmn0623-1.html
anil299.tripod.com/vol_001_no_002/pg001.html
www.adelaideoldterraces.com.au/aap/
The purity (weight-percent lithium) of the sample was easy to calculate (especially after Yehoshua Sivan pointed out the error in my first attempt). The pills weigh 0.4163g each and are clearly labeled as containing 300mg (0.3g) of lithium carbonate (Li2CO3) each. Multiply this ratio by the ratio of twice the atomic weight of lithium to the molecular weight of lithium carbonate and you learn that the pills are about 13.6% elemental lithium.
Source: Raph Levien
Contributor: Raph Levien
Acquired: 30 December, 2002
Text Updated: 11 March, 2007
Sample from the RGB Set.
The Red Green and Blue company in England sells a very nice element collection in several versions. Max Whitby, the director of the company, very kindly donated a complete set to the periodic table table.
To learn more about the set you can visit my page about element collecting for a general description or the company's website which includes many photographs and pricing details. I have two photographs of each sample from the set: One taken by me and one from the company. You can see photographs of all the samples displayed in a periodic table format: my pictures or their pictures. Or you can see both side-by-side with bigger pictures in numerical order.
The picture on the left was taken by me. Here is the company's version (there is some variation between sets, so the pictures sometimes show different variations of the samples):
Source: Max Whitby of RGB
Contributor: Max Whitby of RGB
Sample from the Everest Set.
Up until the early 1990's a company in Russia sold a periodic table collection with element samples. At some point their American distributor sold off the remaining stock to a man who is now selling them on eBay. The samples (except gases) weigh about 0.25 grams each, and the whole set comes in a very nice wooden box with a printed periodic table in the lid.
To learn more about the set you can visit my page about element collecting for a general description and information about how to buy one, or you can see photographs of all the samples from the set displayed on my website in a periodic table layout or with bigger pictures in numerical order.
Source: Rob Accurso
Contributor: Rob Accurso
Text Updated: 20 November, 2008
Pacemaker batteries.
These batteries are designed to be implanted in patients to power their cardiac pacemakers. The seller reports they are from the liquidation of a biomedical products company and had an original list price of $500 each. Jeez, for that price I'll slice my own chest open and drop in a couple of Duracells. They are probably single-use lithium batteries, but maybe they are lithium-ion rechargeable, I'm not sure. No, I won't sell you one for your pacemaker.
Note that these are, from a safety point of view, probably superior to the one I have listed under plutonium.
Source: eBay seller heruur
Puffed-up laptop battery.
Defective lithium laptop battery that puffed up to twice its normal thickness. Here you can see a second one taken out of its outer casing:
Source: Theodore Gray
Contributor: Wolfram Research
Acquired: 1 January, 2007
Vacuum packed slug.
This is an amazing rough cylinder of lithium metal. Amazing because it's so incredibly light. It seems to weigh almost nothing, especially if you pick it up knowing it's made of solid metal, which it is. The density of lithium is half that of water, far lighter than anything you normally think of as a light metal (magnesium, beryllium, aluminum, titanium, all these are three to nine times denser than lithium).
It's vacuum packed in plastic to prevent it from rapidly turning into lithium oxide dust: It's not stable in air, and even in this packaging it's not going to last long: You can already see spots of oxidation forming on the surface as air and water diffuse through the plastic. This is of course one reason why people don't make things out of lithium: They wouldn't last long. The other reason is that it's quite soft, useless as a structural metal.
Source: Juan Jimenez
Contributor: Juan Jimenez
Lithium grease.
For some reason lithium makes grease better, so they put it in and sell it as "lithium grease".
Source: Harbor Freight Tool Company
Acquired: 11 March, 2009
Lithium battery.
An example of a typical AA lithium battery.
Lithium carbonate pills.
Another view of lithium carbonate pills for bipolar disorder.
Small lithium battery.
This is a small battery, or really thick button cell, depending on how you look at it.
Acquired: 2 April, 2009
Text Updated: 3 April, 2009
Larger lithium battery.
This is a lithium battery meant for some kind of camera.
Another brand of lithium carbonate pills for bipolar disorder.
Lepidolite from Jensan Set.
This sample represents lithium in the "The Grand Tour of the Periodic Table" mineral collection from Jensan Scientifics. Visit my page about element collecting for a general description, or see photographs of all the samples from the set in a periodic table layout or with bigger pictures in numerical order.
Source: Jensan Scientifics
Contributor: Jensan Scientifics
Composition: K(Li,Al)3(Si,Al)4O10(F,OH)2
Triphylite from Jensan Set.
This sample represents phosphorus in the "The Grand Tour of the Periodic Table" mineral collection from Jensan Scientifics. Visit my page about element collecting for a general description, or see photographs of all the samples from the set in a periodic table layout or with bigger pictures in numerical order.
Composition: LiFePO4
Petalite.
Description from the source:
Petalite (Li Al Si4 O10 mon.), Mogok, Myanmar (Burma). Isolated, fracturated beige crystal, rare. 2,5x1,6x1 cm; 5 g.
Source: Simone Citon
Contributor: John Gray
Text Updated: 1 October, 2008
Price: Trade
Composition: LiAlSi4O10
Elbaite.
Elbaite (Na (Li Al)3 Al6 (BO3)3 Si6 O18 (OH)4 trig.), Stak Nala, Haramosh, Skardu, Baltistan, Pakistan. Fascicular crystals on matrix. 4x2,5x1,5 cm; 12 g.
Acquired: 30 October, 2008
Text Updated: 31 October, 2008
Composition: Na(LiAl)3Al6(BO3)3Si6O18(OH)4
Photo Card Deck of the Elements.
In late 2006 I published a photo periodic table and it's been selling well enough to encourage me to make new products. This one is a particularly neat one: A complete card deck of the elements with one big five-inch (12.7cm) square card for every element. If you like this site and all the pictures on it, you'll love this card deck. And of course if you're wondering what pays for all the pictures and the internet bandwidth to let you look at them, the answer is people buying my posters and cards decks. Hint hint.
Composition: HHeLiBeBCNOFNeNaMg AlSiPSClArKCaScTiVCrMn FeCoNiCuZnGaGeAsSeBrKr RbSrYZrNbMoTcRuRhPdAg CdInSnSbTeIXeCsBaLaCePr NdPmSmEuGdTbDyHoErTm YbLuHfTaWReOsIrPtAuHgTl PbBiPoAtRnFrRaAcThPaUNp PuAmCmBkCfEsFmMdNoLrRf DbSgBhHsMtDsRgUubUutUuq UupUuhUusUuo
Lepidolite.
Lepidolite (K (Li Al)3 (Si Al)4 O10 (F OH)2 mon.), Varutra"sk, Skellefteao, Va"sterbotten, Sweden. Laminar deep purple crystals on matrix. 5x3,5x3 cm; 45 g.
Composition: K(LiAl)3(SiAl)4O10(FOH)2
Lepidolite (K (Li Al)3 (Si Al)4 O10 (F OH)2 mon.), Aracuai`, Minas Gerais, Brazil. Little crystals on clear Quartz. 1,2x0,8x0,8 cm: 1 g.
Elbaite (Na (Li Al)3 Al6 (BO3)3 Si6 O18 (OH)4 trig.), Minas Gerais, Brazil. Isolated, terminated crystal with rare pink-orange color. 2,3x0,8x0,8 cm; 4 g.
Kunzite.
Price: Anonymous
Composition: LiAl[Si2O6]
Mica sheet.
This is a sheet of mica, a papery thin mineral that was often used as an electrical insulator. The term mica refers to a range of specific minerals and I don't know which one this is exactly, so the composition is just a guess.
Source: Mark Peterson
Contributor: Mark Peterson
Composition: (KLi2Al(Al,Si)3O10(F,OH)2

redpajama_set_name: RedPajamaCommonCrawl


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Ballet Obituaries and Memorials
Ballet News & Issues
Nina Sorokina
October 9, 2011 in Ballet Obituaries and Memorials
The death of Nina Sorokina yesterday at age 69 is announced. The only press I have seen so far is in French, but here is the link:
http://fr.ria.ru/culture/20111008/191404125.html
http://www.youtube.com/watch?v=enU6KX5x7IQ&feature=channel_video_title
MakarovaFan
Very sad. My condolences to her husband Yuri Vladimirov.
http://www.bakutoday.net/died-in-moscow-ussr-peoples-artist-nina-sorokina.html
69 (or 70 as one of the articles says) seems rather young. How sad.
I saw her twice that I remember--both times dancing Flames of Paris pas de deux with Vladimirov as part of a Bolshoi "highlights" program. The first time, I was a very little girl (had only been allowed to go because there was an unexpected spare ticket) and I was totally overwhelmed--though I must admit, mostly by Vladimirov's leaps. But it was altogether a memorable performance. Pretty much my first experience of what now seems very much "old style" Bolshoi bravura dancing. And very exciting to a child who had never dreamed of such a thing!
Thank you for posting this sad news.
I first saw Nina Ivanovna Sorokina dance in 1965. She was a technical breath of fresh air with perfect turnout and an electrifying technique and a real joy in her dancing. I was 20 years old and probably impressionable. Later exposure to this very sweet person and her husband confirmed both of their powerful technical abilities who truly brought both joy and drama to their performances.
My condolences to Yuri Kuzmich Vladimirov on the loss of his wife who danced with the Bolshoi Ballet from 1961 to 1988.
Madame Sorokina received the Gold medal at the 1st International Ballet Competition in Moscow with M. Baryshnikov and the Gold medal at International Ballet Competition in 1966 in Varna. In 1970 she received the "Golden Star" at the International Festival of Dance in Paris.
Madame Sorokina performed many of the leading ballerina roles of the Bolshoi Ballet partnered by her husband to which they brought a virtuosic dynamism and was also variously partnered by Mikhail Lavrovsky, Maris Liepa and Alexander Godunov.
Her leading roles included, The Chosen Maiden in "Rite of Spring" Kasatkina and Vassileva,. Nina ….took leading roles in ,The Geologists , Asel , Anna Karenina , Icarus" and in the classics, Aurora in "Sleeping Beauty", Masha in "Nutcracker", Kitri in "Don Quixote as well as Phrygia in Spartacus, Ivan the Terrible and Mistress of the Copper Mountain in The Stone Flower.
In 1987 she was named People's favorite artist in USSR and in 1988 she became the Ballet Director of the company "Stars of Bolshoi Theatre."
In the last phase of her theatrical life she was a leading teacher of the Russian Academy of Theatre Arts (GITIS) where she was appointed professor of the Department of Choreography. Her other responsibilities were Art Director of seminars for teachers of classical ballet.
And in a curious work that appears to translate as "Naughty Limericks" Nina Sorokina is distinguished by the bright blue top to her costume.
RIA-NOVOSTI Tribute with photographs.
http://www.microsofttranslator.com/bv.aspx?from=fr&to=en&a=http%3A%2F%2Ffr.rian.ru%2Fphotolents%2F20111010%2F191418391.html
Nina Sorokina's funeral took place on Tuesday 11 October with Boris Akimov reading the Eulogy.
From Today's NY Times:
http://www.nytimes.com/2011/10/13/arts/dance/nina-sorokina-dancer-with-the-bolshoi-dies-at-69.html?ref=arts


NEW YORK, May 30 -- Foreign investment as a shorthand for progress: that is the subtext of a new World Bank report, "2006 Global Development Finance," embargoed until minutes before this report. The report, which should now be available online, uncritically presents what it calls "surging capital flows" as positive. The report denounces "regulatory burdens" and praising any "simplifying... of capital controls." It's a Manichean World (Bank) -- anything that might slow such surges down is bad, any increase is good. But for whom?
Inner City Press questioned the report's lead author, Mansoor Dailami, and his trendy colleague Hans Timmer at the United Nations on May 25. It was a full five days before anything could be written. One journalist remarked that while a heads-up is nice, a five day embargo conveys an over-development sense of this development report's importance. On May 25 in the basement of UN headquarters, the Permanent Forum on Indigenous Issues (PFII) was meeting. Bolivia's new foreign minister had explained his government's nationalization of the natural gas industry, to combat foreign producers rip-off of his country. Inner City Press asked about this, but the World Bank authors' faith in free markets was unshaken. They referred to a need to periodically re-divide the rent -- but foreign investment and ownership of a poor nation's infrastructure was the only way to go, they implied.
Inner City Press asked about the recent case in which the U.S.-based hedge fund Lone Star is paying $100 million for misdeeds during its buying and selling of Korea Exchange Bank (KEB). Citigroup faces even more serious challenges in Korea to its acquisition of KorAm Bank, including workers' strikes and charges of predatory lending. The World Bankers shrugged and referred to "specific cases," as in, "actually results may different" or "past events do not guarantee future performance." The World Bank web site contains another report, reciting that "Citigroup acquired KorAM Bank. Similarly, acquisitions of Korea Exchange Bank and LG Card, are expected to be major determinants of direct investment inflows for 2006."
With Paul Wolfowitz slated to visit Seoul on May 30-31, perhaps he'll take the time to see the other side of Citigroup's and Lone Star's moves in South Korea.


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COLUMBIA– South Carolina Attorney General Alan Wilson announced plans for a major initiative among state agencies to combat corruption and protect public integrity in Charleston this morning.
The Attorney General's Public Integrity Unit will bring together dedicated resources and expertise to more efficiently and effectively investigate and prosecute criminal violations of the public trust. The partnership will include the Attorney General's office, the State Law Enforcement Division, the Department of Revenue, the State Ethics Commission, and the Inspector General's office.


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Home > Look > The Incontri: A Magical Meeting in the Siena Province
The Incontri: A Magical Meeting in the Siena Province
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by Sue Finley
Photos (unless indicated) by Paul Flanagan
https://look.thoroughbreddailynews.com/wp-content/uploads/2019/08/TDN-Stories-La-Foce-Episode-6-.mp3
(Click the arrow above to play the podcast.)
I have always loved old churches–the kinds you come across in rural towns in Europe where the stone steps are worn with the footsteps of time, where you sit in the pews and imagine the centuries of souls who sat there before you celebrating their joys, mourning their losses, and passing time in the quiet contemplation of life. More than any other place, they seem, to me, to be the places where history is housed.
I had cause to think of this recently as I sat in the the Pieve di Corsignano, the 12th century Romanesque stone church where Pope Pius II was baptized. Parts of it date back to the 800s, before Pius would develop the town up the hill from the church into what we know as Pienza today, and name it after himself. It is now the oldest existing planned city in the world, and one of the most beautiful places you will ever visit.
the Pieve di Corsignano in Siena was built from 800-1100 | Paul Flanagan photo
On this day, the church is not quiet; in fact, it is filled with the sorts of sounds you might have heard there those many centuries ago; the sounds of chamber music, violins, string ensembles, and even dueling cellos, with some of the most talented musicians in the world.
The experience of sitting in this semi-darkened church overlooking the Val d'Orcia, one of Italy's most beautiful vistas, with just around 200 other people and listening to this music is so profound, and such a rare chance to focus in today's world full of distractions, that leads me to start thinking about all of the things I value and enjoy in life. Travel, certainly, and history. Family, tradition, art, great food and fine wine, friendship, landscape, scenery and beauty. And now, music.
And so it occurs to me soon after that Antonio Lysy, a cellist and professor at UCLA who grew up a stone's throw from this place where we sit today, has taken all of these things that we value in life and has managed to stir all them together in a pot and create one experience that combines so many elements of beauty that I struggle to write about it for fear of not doing it justice. That experience is the Incontri in Terra di Siena (ITS), a music festival that is, at its heart, about the best that life has to offer.
The countryside near La Foce | Sue Finley photo
A disclaimer: I'm not a music person. Not that I don't like music; I do. But I have never played an instrument, or had a favorite composer and until July, I had been to exactly one classical concert in my life, an outdoor recital by the Denver Symphony Orchestra when I was a child. It was magical, but I never went back. The Incontri in Terra di Siena, `Meetings in the Land of Siena,' a classical music festival which celebrated its 31st rendition this year, now has me wondering why.
This year's festival is comprised of eight concerts that take place over nine days in different locations in the Siena province; most indoors, but some out. There are also book presentations and historical talks related to the area, and it is for the latter that I am present here.
The ITS continues to be a place for artistic encounter and inspires us to make our humble contribution for a better and more humane world." –Radovan Vlatkovic
The festival is not solely about the history of its home, La Foce, or about its founder, Antonio Lysy, but it would be remiss not to understand them in this context and as the main backdrop.
La Foce was once a 7,500-acre estate, now about one-third that size, in central Italy where 58 farming families once lived and worked, farming the land under the guidance of its owners, Iris and Antonio Origo, Lysy's grandparents. Origo is a celebrated literary figure who documented the changes she and her husband brought to the area, including hospitals, schools, literacy, modern farming techniques; in short, better lives. She also documented the intrusion of World War II into their world in a celebrated diary, War in Val d'Orcia, in which she described how the family struggled to keep the farm going, all while providing aid and sheltering displaced children and members of the Allied forces, including escaped POWs. I know from personal experience that there is no revisionist history here; my father was one of those she saved.
That's La Foce's past. Today, still managed by the Origo family, it draws a steady stream of visitors from around the world who come to stay in its farmhouses, B&B and villa apartments. Many, having read Origos' books, come to experience a place where such profound history occurred. Some come to get married in the iconic English garden. Others come for the music.
La Foce's English garden overlooks the Val d'Orcia, a UNESCO Heritage site | La Foce photo
When Lysy dreamed up the idea of the festival, La Foce was struggling through a difficult period. Like the rest of society, post-war Italy had seen a migration of laborers from farms to factories, as the economic engine changed from farming to manufacturing. Lysy's grandparents were celebrated in the region, and Iris's books had created a curiosity about the estate. It occurred to Lysy that allowing the public inside, through a concert series, would be welcome by all. He and his mother Benedetta Origo, launched the festival in 1988.
"My grandparents valued their privacy," said Lysy, "and in their advanced years La Foce was quite a secluded place; with a beautiful walled garden that nobody but family and close friends had access to. With time, more and more people started visiting and I believe the concerts had a lot to do with initiating that." At the same time, his mother, Benedetta, led the charge to rebuild the farmhouses as holiday rentals, profiting from the government's agriturismo movement to lure people to Italy for a Tuscan holiday.
The result is a mix of history, culture, scenery and landscape that would be hard to replicate.
In fact, some of the world's top musicians cite those things as reasons to choose this festival over others.
Lysy prepares to play in Pienza | Sue Finley photo
Lawrence Power is one of the world's foremost violists, a young musician based in London, and in demand worldwide. On this night in Pienza, he joins the Calidore String Quartet in the medieval church to play Antonin Dvorak's String Quintet No. 3 in E major. Calidore, a likeable, talented group of young musicians have drawn their own raves as well, and are praised by critics for acting as one organism. "A miracle of unified thought," said one review. The audience is riveted. No one checks their phone or watch, and I lean forward along with them as if to better see what will happen next. When they are finished, the applause is thundering.
Jeremy Berry is Calidore's violist; a Juillard graduate who lives in Manhattan and is attending his first Incontri in 2019. Berry spends more than half the year on the road with the quartet, and he and the other musicians experience a range of performance atmospheres, from large venues to living rooms, and from impersonal hotel chains to what he finds here at the Incontri. Here, at La Foce, the musicians stay together in the Chiarentana villa apartments. Chiarentana is a separate and charming part of the estate managed by Iris's daughter Donata, also consisting of homes and apartments for rent.
"It has been amazing," said Berry after concluding a concert one night. "There aren't too many places you come to that have scenery quite like this. Actually, there are no other places. And with all of the other musicians and fans that come to the concerts, and the donors, it's a tight-knit family, community type of feeling, which has been really pleasant. As a Manhattan-based artist, when you're working to create this incredibly beautiful music, it's hard to feel the fantasy and nuance you need to feel when you're surrounded by this concrete jungle with car horns and sirens that wake you up at 6 a.m. every day. You come to a place like this, also with other artists that are so tremendous, and it's an incredibly inspiring place from which to create."
The artists stay and dine in individual apartments in Chiarentana, a castle which dates back to the Middle Ages | photo courtesy Chiarentana
"Sometimes we play in places that are smaller, like living rooms, while most often we perform in large concert halls," Berry said. "The fun of what we do is that it's completely different every time and it causes us to play the music differently, in turn. Here, from the audiences, we feel an amazing appreciation. A concert really is a two-way street. I don't know if there are subconscious cues that you pick up from the audience or what, exactly, but you really feel the energy if you're holding the audience. Here, there has been a palpable appreciation and excitement."
Lysy said that he worked from the start to create that atmosphere, not just by attracting top talent, but by inviting collaborative musicians who are, in a word, nice. That creates not only a good atmosphere, he said, but better music. This philosophy is also shared passionately by the current Artistic Director Alessio Bax, a distinguished, prize-winning Italian concert pianist living in New York.
"We mastermind a true matchmaking kind-of-thing with the musicians because it's really an intricate business to achieve the right mix," he said. "Just one person can make a whole group very unhappy. It's not as if we're paying them a huge fee to come here, so we try to offer them practically everything else they value, at the highest standards; the venues, the music-making, the accommodation and food, and just participating with the people that they really want to spend time with. So, it becomes for them a unique retreat, which we hope they will not want to leave! Our audiences witnesses that. They see our efforts and joy crowned in the concerts."
Saturday night's concert is held at the Chiesa di Sant'Andrea, a medieval church in the village of Castiglioncello del Trinoro, a town so charming that American attorney Michael Cioffi has purchased most of it to ensure its survival, remodeling the ancient homes into luxury accommodations under the name of Monteverdi. The town is perched at the top of a hill overlooking the Val d'Orcia and was down to nine inhabitants when Cioffi first came here. It is now a quiet but thriving hub of cultural activity and exceptional dining.
The church of Chiesi de Sant'Andrea in Casiglioncello del Trinoro | Paul Flanagan
Benjamin Beilman is a 29-year-old solo violinist who has been called "monstrously talented" by the Philadelphia Inquirer, and "muscular with a glint of violence" by the New York Times. He is, above all, compelling to watch. On this night, Beilman has a prominent duo collaboration with Alessio Bax, Ferruccio Busoni's virtuosic Violin Sonata n. 2 in E minor, op. 36a, and that muscular violence is on display. I sit in the back of the darkened space as a thunderstorm rages outside the church doors, and watch the audience watch them, and they are nothing less than stunned at their performance.
"Most of what we do in classical music resides in the 18th and 19th century and so getting back into those places where a lot of that music was composed, or during that period, and feeling like you're connected to people who deeply, deeply want to hear it, is a very special feeling," said Beilman, also attending his first Incontri. "You feel it both as you're playing, and obviously after. Those people are so close to you, you can immediately tell if they're shifting around in their chair, if they're looking at their watch. You know when they're sitting completely still, and you feel that electricity in the air; they're constantly focused on you. It makes a huge difference. What we do in the practice room is very important, but ultimately, the quality of a performance is only as good as the attention that the audience provides."
Beilman, left, rehearses with Annabelle Meare, Power, Lysy and Nabil Shehata. | Sue Finley photo
Beilman, like other in-demand musicians, has the privilege of what to choose on the summer festival circuit, and like Berry, he cites the landscape of the Val d'Orcia as one of the major draws of the Incontri. "The most immediate thing that stands out is the terrain and the surroundings," says Beilman of his initial experience here. "The sheer natural beauty is a huge part of this festival. Summer has so many weeks and for musicians who are in relatively high demand, you can sort of have your pick of where you want to go. Being here tonight and experiencing this kind of very intimate ancient church packed with people is a very special feeling."
"This kind of very intimate ancient church packed with people is a very special feeling." –Benjamin Beilman
Saturday's performance, as well as Sunday's final one on my visit, also features solos from the world-renowned Croatian-born French horn soloist Radovan Vlatkovic. He has been to the Incontri in the past, and has formed a strong bond with Lysy and Bax. He's a soft-spoken, interesting and worldly person with a kindly air, and as I listen to him play, I can hear the stories that his passionate embrace of the music tells. As they seem to be at the conclusion of all of the performances, the audiences are overcome, as am I.
Vlatkovic in a pensive moment outside the church in Castiglioncello del Trinoro | Paul Flanagan
"On my first visit two years ago I visited the gardens at La Foce, and was told part of the story and also acquired books by Iris Origo," said Vlatkovic. "We feel the sense of tradition and continuity through the work of Antonio's family with whom he started the festival. Certainly Iris Origo's presence is felt through her books and this unique estate which is her and her husband's legacy."
"As travelling musicians, there is indeed a strong sense of solidarity, bond and mutual support. At festivals we go through a short but very intense period which sometimes seems between dream and reality. The memories stay forever. And so the ITS continues to be a place for artistic encounter and inspires us to make our humble contribution for a better and more humane world."
Vlatkovic's words make you realize that Lysy's apple hasn't fallen far from his grandmother's tree.
It's the last night of the concert, and Vlatkovic has finished performing. He stands behind the back row of the last aisle of the audience in the old granaio at La Foce, where tonight's outdoor concert has been moved due to inclement weather. The change in venue means that every last space is taken up by the audience. Beilman, Annabelle Meare, Lysy, Power and the Calidore string quartet are closing the concert with George Enescu's Octet for strings in C, op. 7, and it's jaw dropping. As the audience delivers a loud and thundering ovation, Vlatkovic stands with the rest of them, cheering. He catches my eye, raising one eyebrow as he shakes his head and smiles to acknowledge the incredulity we both feel.
I may not know a lot about music. But I know I that what I have just seen is something extraordinary.
For more information on the festival or how to attend in 2020, visit www.itslafoce.org.
Antonio LysyAntonio OrigoChiarentanaIncontri in Terra di SienaIris OgigoITSLa FoceMichael CioffiMonteverdi TuscanyWar in Val d'Orcia
by Sue Finley, Susan Finley
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David Burke: Super-Chef With Racing Connections


This multi-use piece converts from necklace to bracelet and will be the jewelry item you use most!
A unique blend of faith and fashion, this necklace easily converts to a wrap bracelet. Beautiful white freshwater pearls are strung together with contrasting brown thread and 24 unique religious medals, crosses, and tokens, including: Divine Mercy medal, Holy Family medal, San Damiano cross, St. Benedict crucifix, Miraculous Medal, Our Lady of Lourdes medal, Our Lady of Fatima medal, and many more. Necklace measures 36". Tokens are burnished metal and range from 3/8" to 7/8". Comes in an organza bag.


Saudi Arabia's cement producers are beating the country's benchmark stock index on speculation they will fare well following US$500bn in government spending and projects.
This year has seen the Tadawul All Share Cement Index, which includes nine stocks, surged 20%, the third-best performance after media and retail stocks and compared with a 7.4% fall in the Tadawul All Share Index. Cement producers offer a dividend yield of 6.6%, second only to transport companies.
"The sector will continue to benefit from large infrastructure spending under way in Saudi Arabia," said Yong Wei Lee of Emirates NBD Asset Management in Dubai to Bloomberg.
King Abdullah announced a US$130bn plan this year to build homes and create jobs in a bid to stave off regional protests that toppled leaders in Tunisia, Egypt and more recently, Libya. The rulings are in addition to a 2010 commitment to spend US$384bn over five years on housing, transport and education.


text:
Layer-specific imaging of retinal degeneration
Duong, Timothy Q (PI)
Research Imaging Institute
DESCRIPTION (provided by applicant): Retinitis pigmentosa (RP) is a group of inherited diseases marked by progressive photoreceptor degeneration, affecting 1.5 million people worldwide. The vascular (choroidal and retinal) layers located on either side of the retina and other (bipolar and ganglion) cell layers are also affected. Current clinical assessment of RP relies heavily on visual testing. Non-invasive imaging technologies capable of detecting layer-specific cellular and vascular changes would enable objective early detection, longitudinal disease staging, monitoring of therapeutic intervention, and improved understanding of the underlying pathophysiology. Optical-based retinal imaging techniques can be limited by media opacity (i.e., cataracts and vitreous hemorrhages) which precludes visualization of deep retinal layers and vessels. In contrast, magnetic resonance imaging (MRI) provides non-invasive images of anatomy, physiology and function without depth limitation. Achieving sufficient spatial resolution for retinal MRI, however, remains challenging. In this proposal, we will develop novel anatomical, physiologic and functional MRI to resolve various layers of the retina at 60x60x500 5m, and vigorously test this capability by longitudinally investigating progressive, layer-specific retinal degeneration in the Royal-College-of-Surgeon (RCS) rat retinas, an established model of human RP. PUBLIC HEALTH RELEVANCE: This proposal outlines the development, cross-validation and application of novel MRI approaches to resolve structural, physiological and functional laminar specificity of the retina at very high spatial resolution. It has strong clinical significance and potential impact to the field in that it can provide 1) an early marker of retinal degeneration and for monitoring therapeutic intervention and 2) powerful insights into how retinal and choroidal blood flow and oxygenation are regulated and how retinal degeneration affects the two vasculatures and the neural tissues they subserve. Data from these animal studies should advance these areas of research, open up new avenues for retinal research, and lay the foundation for future human studies.
National Institutes of Health: $46,605.00
National Institutes of Health: $176,418.00
Retinal Degeneration Medicine & Life Sciences 100%
Retinitis Pigmentosa Medicine & Life Sciences 74%
Retina Medicine & Life Sciences 70%
Magnetic Resonance Imaging Medicine & Life Sciences 53%
Vitreous Hemorrhage Medicine & Life Sciences 26%
Retinal Vessels Medicine & Life Sciences 23%
Ganglia Medicine & Life Sciences 19%


text:
Q: How to check atomic object impact in producer / consumer schema? I want to implement the following

*

*Two threads: producer (can change shared variable a), consumer (waiting for shared variable change)

*I want to use atomic to synchronize threads

Problem - I was running my code with int a; and std::atomic<int> a;  but in 100% cases I have the same result on my PC.
calculate_val
process 1

How can I see changes of code with and without atomics?
using namespace std;

atomic<int> a; // I was replacing with int a; and always have the same result
int val;

int calculate_val() {
    cout << "calculate_val " << endl;
    return 1;
}

void process(int val) {
    cout << "process " << val << endl;
}

void threadProducer() {
    val = calculate_val();
    a = 1;
}

void threadConsumer() {
    while (!a) {

    }
    process(val);
}

int main() {
    thread t2(threadConsumer);
    thread t1(threadProducer);

    t2.join(); // was trying to change order
    t1.join();
    return 0;
}

A: Your scenario is too simple. On an architecture with strongly ordered memory semantics (e.g. x86 and descendants, which, given you refer to "my PC", is probably what you're using), with compiler optimizations turned off, as long as the compiler doesn't reorder threadProducer's a = 1; ahead of the function call (it has no reason to), doesn't cache the value of a for the while (!a) test, and doesn't eliminate the while(a){} loop, the atomics won't make a difference.
Your existing code could fail without atomics:

*

*On a machine with weakly ordered memory semantics (the writes to a and val could become visible in threadConsumer in any order, and it could take an arbitrarily long for them to become visible). I suspect the locking built-in to the iostream library, and the C stdio it wraps, would probably trigger cache flushes though, so your I/O trying to observe the races is in fact changing the behavior.

*On any machine if the compiler chose to cache the value of a in threadConsumer for efficiency (non-volatile, non-atomic values can be cached to save overhead because it's assumed they're only accessed from one thread, and the loading thread isn't changing it).

*On any machine if the compiler decides to eliminates the while (a) {} loop, due the non-atomic a potentially creating an infinite loop if cached as suggested in #2.

*On any machine if the compiler chose to reorder a = 1; ahead of val = calculate_val(); (since neither line depends on any values computed in the other line, an optimizing compiler could choose to do them in either order). In practice, given the aforementioned locking in the I/O layers, the compiler won't swap these lines, but it could if the I/O were removed.

I'm not going to give an example of things that could go wrong, because a cursory search will find all sorts of examples of when and why you use atomics. What's important to know is that, even in your simple scenario where you thought it was safe without them, it wasn't. Even turning up optimizations might cause your code with a non-atomic a to stop behaving on x86-64 machines, and x86-64 is already threading/atomics on easy mode.

redpajama_set_name: RedPajamaStackExchange


text:
Proteus Airlines (código IATA: YS - código OACI: PRB - Indicativo: Proteus) fue una aerolínea regional de Francia, cuya sede central estaba en Saint-Apollinaire, Côte-d'Or, cerca de Dijon, y Saint-Étienne.

Tiene el certificado de operador aéreo N.º F-023 CE expedido por el Centro Oriente de la DAC de 30 de junio de 1998 , y una licencia otorgada por la DGAC el 29 de marzo de 1996.

Historia

La aerolínea fue conocida originalmente como Proteus Air System.

 1986 : creación de Proteus Airlines System.
 1988 : La empresa obtiene su primer certificado de transporte aéreo para el funcionamiento de un Beechcraft 90.
 1990 : Tres nuevas líneas están abiertas desde Dijon.
 1996 : Proteus Airlines System cambió de nombre y pasa a llamarse Proteus Airlines. Air France cede a Proteus Airlines la operación de rutas nacionales e internacionales con dos aeronaves Dornier 328, tras la firma de un acuerdo de franquicia. Una línea Lyon - Lorient se abre con un Beechcraft 1900.
 1997 : Proteus Airlines reúne todas sus actividades operacionales y técnicas en el aeropuerto de Lyon-St Exupéry (actualmente Lyon Saint-Exupéry) y crea una dirección de las operaciones aéreas para supervisar la parte comercial.
 1998 : Desde febrero de 1997 a julio de 1998 el número de vuelos diarios se incrementó de 14 a más de 120. El 10 de junio de 1997 , la reestructuración de la DAC Centro-Oriental hace que este organismo inicie una auditoría de la empresa, que da un resultado satisfactorio.
 1999 : En octubre de 1999, Proteus Airlines compra la compañía regional francesa Flandre Air.
 2000 : Proteus Airlines y Flandre Air son ambas reagrupadas bajo el nombre de Proteus Airlines.
 2001 : El 30 de marzo de 2001 Proteus, Flandre, y Regional Airlines se unificaron en la compañía filial del Grupo Air France llamada Régional Compagnie Aérienne Européenne.

Flota

La aerolínea Proteus Airlines, debido a su actividad limitada al transporte de personas a nivel regional en Francia, ha operado con aviones pequeños.

 Beechcraft 90, el primer avión con el que operó en 1988.

 Beechcraft 1900, en la línea Lyon - Lorient.

 Beechcraft 1900D.

 Dornier 328, cedidos por Air France.

Accidente
El 30 de julio de 1998 el Vuelo 706, un Beechcraft 1900D, matrícula F-GSJM de Proteus Airlines chocó con un Cessna 177 matrícula F-GAJE. El accidente causó la muerte de 15 personas.

Notas

Enlaces externos
 Puedes ver el logo de Proteus Airlines en el archivo de la Wikipedia en francés: Proteus Airlines logo.gif
 Proteus Airlines (Archivo)
 Imágenes de la flota de Proteus Airlines en:
 jetphotos.net
 airliners.net
 planepictures.net

Aerolíneas desaparecidas de Francia
Francia en 1996
Francia en 2001
Empresas fundadas en 1996
Aerolíneas desaparecidas en 2001

redpajama_set_name: RedPajamaWikipedia


text:
Q: Android Sound: seekTo and setPlaybackRate I am looking for a possibility to play audio on an Android device, that lets me both use the seekTo function(stepping in at a specified part of the audio file) and setPlaybackRate(speeding up/down the playback rate). However, taking a look at the media classes Android provides I could only find the following.
SoundPool: Lacks seekTo
AudioTrack: Lacks seekTo
MediaPlayer: Lacks setRate
Is there a way to play audio in Android without having to write too much code on my own that supplies both these functionalities?

A: I think that OpenSL has what you need, but I haven't used it personally. Maybe this here Android : How to change Playback Rate of music using OpenSL ES will help you.


text:
Notified Body Accepts Echo Therapeutics' Clinical Trial Plan for Symphony® CGM System
Data from the trial will support CE Marking
PHILADELPHIA, May 29, 2013 /PRNewswire/ -- Echo Therapeutics, Inc. (Nasdaq: ECTE), a company developing its needle-free Symphony® CGM System as a non-invasive, wireless, transdermal continuous glucose monitoring system, today announced that it has received agreement from its Notified Body inEurope on its clinical trial plan. Following completion of the clinical trial, the company will submit the analyzed data to the Notified Body in a Technical File in support of its Symphony CE Mark application.
(Logo: http://photos.prnewswire.com/prnh/20120801/NE50071LOGO)
"We are very pleased with the positive outcome of the Notified Body's pre-assessment of our clinical trial plan. We are working very closely with the clinical trial sites as we prepare for the imminent commencement of the study," commented Dr. Mooney, Chairman and CEO of Echo Therapeutics. "Data from this study will support the safety and performance of Symphony needed to obtain marketing approval in Europe."
About Echo Therapeutics
Echo Therapeutics is developing the Symphony CGM System as a non-invasive, wireless, transdermal continuous glucose monitoring system. Our target is patients who could benefit from glucose monitoring in the hospital setting, including critical care. Significant opportunity also exists for patients with diabetes to use Symphony in the outpatient setting. Echo is also developing its needle-free skin preparation component of Symphony, the Prelude® SkinPrep System, as a platform technology to enhance drug delivery of topical pharmaceuticals.
Cautionary Statement Regarding Forward Looking Statements
The statements in this press release that are not historical facts may constitute forward-looking statements that are based on current expectations and are subject to risks and uncertainties that could cause actual future results to differ materially from those expressed or implied by such statements. Those risks and uncertainties include, but are not limited to, risks related to regulatory approvals and the success of Echo's ongoing studies, the failure of future development and preliminary marketing efforts related to Echo's Symphony CGM System, Echo's ability to secure additional commercial partnering arrangements, risks and uncertainties relating to Echo's and its partners' ability to develop, market and sell the Symphony CGM System, the availability of substantial additional equity or debt capital to support its research, development and product commercialization activities, and the success of its research, development, regulatory approval, marketing and distribution plans and strategies, including those plans and strategies related to its Symphony CGM System. These and other risks and uncertainties are identified and described in more detail in Echo's filings with the Securities and Exchange Commission, including, without limitation, its Annual Report on Form 10-K for the year ended December 31, 2012, its Quarterly Reports on Form 10-Q, and its Current Reports on Form 8-K. Echo undertakes no obligation to publicly update or revise any forward-looking statements.
Christine H. Olimpio
Director, Investor Relations and Corporate Communications
- Visit our website at www.echotx.com
- Follow us on Twitter at www.twitter.com/echotx
- Join us on Facebook at www.facebook.com/echotx
SOURCE Echo Therapeutics, Inc.


The traditional logic underlying most cases of sanctions has tended to view the imposition of high economic costs as the means necessary for achieving political success. This project challenges that conventional wisdom by presenting ethical and practical problems with the logic behind the traditional model of sanctions.
In 2003 CSCW and the International Department of the Norwegian Red Cross organized a public forum exploring the humanitarian consequences of economic sanctions, particularly in light of recent developments in Iraq.
The main output of this project is a report authored by David Lektzian and entitled "Making Sanctions Smarter: Are Humanitarian Costs an Essential Element in the Success of Sanctions?". The report was presented at the August 2003 Humanitarian Forum on Economic Sanctions at the Norwegian Red Cross headquarters in Oslo to an audience of scholars, political leaders and practitioners. The full report is available in electronic format here, or may be ordered in hard-copy by contacting PRIO's Information Department.
After laying out the theoretical arguments, hypotheses derived from the traditional model, and a smart model of sanctions, are tested empirically. The empirical analysis combines a quantitative analysis of 104 pre-1990 sanctions cases with a summary of detailed case studies of 12 UN sanctions primarily drawn from the post-1990 period. The major conclusion drawn from the empirical analysis is that economic sanctions are not about economics. They are about politics. Imposing high degrees of economic hardship – and the humanitarian costs that follow – not only introduces serious ethical concerns, but high cost sanctions are also no more likely to be successful than sanctions that impose lower costs.


From the first moment a visitor arrives at The Ridges, an exclusive community within the master-planned Summerlin development, the enchantment is palpable. A seamless weaving of natural beauty, desert contemporary architecture and luxury amenities contribute to the immense appeal of The Ridges. The prospect of coming home to The Ridges feels like a good choice. In a sense, it feels right!
The winning combination of noteworthy architecture, the privacy of ridgetop living, and the signature lifestyle and culture of Summerlin offer an extraordinary opportunity for new home buyers.
Some of our finest listings are located in Promontory, a distinctive gated community that melds homesites featuring captivating Bear's Best Golf Course views with expansive natural vistas and the dazzling lights of the Strip. Promontory was one of the first-established neighborhoods within The Ridges, with only 59 half-acre and larger homesites. The neighborhood features a private park and walking trails.
The Ivan Sher Group, with a professional approach, dedication to service and more than two decades of local experience in real estate, is a prudent choice for discerning sellers and buyers alike. We will be pleased to introduce you to the unique ambience, stunning settings and exquisite homes that are the hallmarks of life at The Ridges.
Now that you've made your mark, your next address could be a home at Promontory, similar to 7 Sable Ridge, 11 Sable Ridge, 4 Wild Ridge, or 16 Wild Ridge, all stunning properties that we represent.


text:
Direct activation of PP2A for the treatment of tyrosine kinase inhibitor–resistant lung adenocarcinoma
Rita Tohmé, … , Jaya Sangodkar, Goutham Narla
Citation Information: JCI Insight. 2019;4(4):e125693. https://doi.org/10.1172/jci.insight.125693.
Research Article Oncology Therapeutics
Although tyrosine kinase inhibitors (TKIs) have demonstrated significant efficacy in advanced lung adenocarcinoma (LUAD) patients with pathogenic alterations in EGFR, most patients develop acquired resistance to these agents via mechanisms enabling the sustained activation of the PI3K and MAPK oncogenic pathways downstream of EGFR. The tumor suppressor protein phosphatase 2A (PP2A) acts as a negative regulator of these pathways. We hypothesize that activation of PP2A simultaneously inhibits the PI3K and MAPK pathways and represents a promising therapeutic strategy for the treatment of TKI-resistant LUAD. After establishing the efficacy of small molecule activators of PP2A (SMAPs) in a transgenic EGFRL858R model and TKI-sensitive cell lines, we evaluated their therapeutic potential in vitro and in vivo in TKI-resistant models. PP2A activation resulted in apoptosis, significant tumor growth inhibition, and downregulation of PI3K and MAPK pathways. Combination of SMAPs and TKI afatinib resulted in an enhanced effect on the downregulation of the PI3K pathway via degradation of the PP2A endogenous inhibitor CIP2A. An improved effect on tumor growth inhibition was observed in a TKI-resistant xenograft mouse model treated with a combination of both agents. These collective data support the development of PP2A activators for the treatment of TKI-resistant LUAD.
Rita Tohmé, Sudeh Izadmehr, Sai Gandhe, Giancarlo Tabaro, Sanjay Vallabhaneni, Ava Thomas, Neal Vasireddi, Neil S. Dhawan, Avi Ma'ayan, Neelesh Sharma, Matthew D. Galsky, Michael Ohlmeyer, Jaya Sangodkar, Goutham Narla
PP2A activation inhibits lung tumor development in an EGFR-driven TKI-sensitive non–small cell lung carcinoma transgenic model.
Options: View larger image (or click on image) Download as PowerPoint
(A) Expression of TRE-EGFRL858R was induced with doxycycline, and mice were administered either vehicle control or 100 mg/kg of SMAP every 48 hours. (B) Axial images obtained using MRI before and after treatment with vehicle control or SMAP. (C) H&E-stained sections of lung samples. (D) Quantification of H&E results. (E) Quantification of MRI results. (F) Immunohistochemical staining to detect apoptosis (TUNEL) and proliferation. Scale bar: 100 µm. (G) Quantification of TUNEL. (H) Quantification of PCNA. (I) Immunohistochemical staining of pERK and pAKT. Scale bar: 20 µm. Respective quantifications are represented as mean ± SD. *P < 0.05; ***P < 0.001.


text:
David Pontin, född 13 september 1687 i Linköping, död 17 maj 1736 i Törnevalla socken, han var en svensk kyrkoherde i Törnevalla församling.

Biografi
David Pontin föddes 13 september 1687 i Linköping. Han var son till kyrkoherden Samuel Pontinus och Maria Tunander. Pontin sturade själv och blev 19 juni 1698 student i Uppsala. Han prästvigdes 10 december 1709 och blev 1710 regementspastor vid Östgöta infanteriregemente. Pontin togs till fånga 1712 i Tönningen och återvände hem 26 juni 1713. Han blev 1717 kyrkoherde i Törnevalla församling. Pontin avled 17 maj 1736 i Törnevalla socken och begravdes 15 juni i Törnevalla kyrka.

Familj
Pontin gifte sig första gången 1717 med Elisabeth Wallerius (1681–1723). Hon var dotter till kyrkoherden Nils Wallerius och Christina Phrygius i Högsby socken. Elisabeth Wallerius hade tidigare varit gift med kyrkoherden Daniel Millberg i Törnevalla socken. Pontin och Wallerius fick tillsammans sonen Samuel (1717–1736).

Pontin gifte sig andra gången 1724 med Christina Collin (1700–1754). Hon var dotter till kyrkoherden Constans Collin och Anna Sithelius i Söderköping. De fick tillsammans barnen Magnus Constans, Anna Maria (född 1731) och David. Efter Pontins död gifte Christina Collin om sig med kyrkoherden Jonas Lidman i Eksjö.

Referenser

Noter

Svenska teologer under 1700-talet
Födda 1687
Avlidna 1736
Män
Präster från Linköping
Svenska präster under 1700-talet


Now this trip, would you believe, ANOTHER Nor'easter hit?? Yup. I am seriously beginning to think a snow storm follows me whenever I have a trip planned!
A horrible snowstorm hit the day before we left and was set to continue through the night. We were leaving for the airport at 5 am and ALL United flights were canceled that day/evening.
I was sure that even if my United flight for the morning was not canceled, that it would be difficult to get to the airport if we could get there at all. I contemplated worried and became anxious about not going.
I awoke at 4 am and the roads were clear. We said we would go to the airport, which is an hour away, and if the roads were bad, then we would turn around.
The roads were perfectly clear all the way.
And our flight was still on time!
Can I just say, that any details I worried and became anxious about never happened? I am SO done with satan and his lies that cause me anxiety. Because I have seen time and again these past two weeks, that if GOD gives you a mission, He will complete it! And there is nothing else to do but rest in that truth and find joy in being in HIS will. The lies and worries that occupy my mind are permanently evicted from here on out!
As I chatted with one of my very favorites this weekend– Heidi St. John- we are WARRIORS for Christ!
This trip was beyond any expectations that I had. One of the best parts was that I traveled with my beautiful daughter. Knowing I only have one year left with her before she is a real-deal adult, I cherished every moment.
We talked, we ate, we shopped, laughed, and we ate some more! It was a treasure. And she was so incredibly helpful with everything. I am so thankful!
And the conference itself was beyond an answer to prayers. I met with so many homeschoolers that were encouraged by the sessions. I loved meeting so many podcast listeners (I really had no idea SO many out there listen!) and it was a joy to get some time with the other speakers- so many that I admire greatly in their ministries.
When He Calls You, Equips You!
It's truly a delight to be able to minister to families and to be walking in the calling that God has given me…even though I never imagined doing this in my wildest dreams! Yet, I couldn't imagine doing anything else these days. I am thankful beyond words.
These two sweet ladies came to every one of my four sessions! They were a delight!
And Arkansas! Oh, Arkansas! What a wonderful place. Truly one of my favorite places that I have visited. The airport is a dream. Smack dab in the middle of farms…it's like they stuck the airport in my little town at home.
And the people! They are SO kind. I have yet to meet anyone that isn't beyond pleasant and friendly. I just love it here.
There is nothing like a Teach Them Diligently event. They are truly special and the heart behind these events is so focused on the Lord. If you have the opportunity to attend one, don't wait! Run! You will not be disappointed!
And then from May 17-19, I will be at Teach Them Diligently in Myrtle Beach! I am so grateful!
Where Dreams Become Reality-The BIG RV Trip!


Untitled, originally uploaded by Qathi.
I like photographs of hands. Here I like the negative space, shadows and the reflected light, as well the angle and the softness implies an intimacy that is appealing to me.


Terms and conditions of Snakebusters® Reptile parties ®, Australia's best reptiles® shows.
Terms and conditions of Snakebusters®, Australia's best reptiles ® shows, displays, reptile parties®, etc.
- We take bookings over the phone, via e-mail, post or fax.
- However it is best to confirm by phone.
- Unless verbal (phone or in person) confirmation is given, then you may not be certain you have booked us.
- Furthermore for all bookings other than childrens parties and emergency snake call outs, we require a written or email confirmation of the booking.
- For all bookings we allow a "cooling off" period for cancellations, rescheduling and so on of one week (7 days).
- Outside of the "cooling off" period (above) for all other cancellations we reserve the right to charge a cancellation fee, chargeable at our discretion and binding on the person or entity who cancel of the amount as per the schedule below (see "cancellation fees" below).
- Pre event promotion (for those who have already booked us) - click here for assistance.
- School incursion bookings, study sheets can be found clicking here and student incursion payment forms can be found clicking here.
- We accept payment by Mastercard, Visa, Amex and Diners, with a 10% loading to cover administration and processing costs.
- Payment for our shows is due within one calender month of the show, or if a series of shows is done, within one calender month of the last show of that calender year.
- We reserve the right to take all forms of legal actions to recover debts.
- After 60 days of booking, if payment is not received or readily recoverable (or if we are earlier told we won't be paid), we may send the debt to agents or take legal action (see "debt recoveries" below).
- We are one of the few licenced reptile exhibitors in Australia to have paid big bucks to get public liability insurance for live reptiles at our shows. We can fax these details to potential clients if need be. Beware: At least some other reptile show outfits in Australia either do not have public liability insurance and/or have made misleading statements to get their policy and/or are not fully covered in terms of their reptiles. If you book with someone else, we cannot guarantee that you will be covered in event of accident.
.....Bites from non-venomous (including "devenomized" or "venomoid") reptiles that may even draw blood, but cause no permanent damage (e.g. Stumpy Tailed Lizards).
.....Scratching by claws of lizards, (generally no bleeding).
.....Whipping by tails of snakes of lizards (no injuries).
.....Defecation by reptiles in terms of soiling clothes or carpets.
.....Minor injuries to live reptiles in the event of mishandling or even being dropped.
All persons booking us, assume the above risks.
- Click here to download an html (webpage) version of our "Risk assessment" (Generic document).
- Click here to download a MS Word (Better for printing) version of our "Risk assessment" (Generic document).
- Note that it is illegal under Sect 32 of the O H and S Act 2004 to demonstrate dangerously venomous snakes in public in Victoria that have not been surgically devenomized.
- A "Risk assessment" should be issued and read BEFORE any booking is made (whether with Snakebusters or anyone else), especially if contemplating taking the risk of bringing snakes with venom glands intact onto a site where members of the public attend.
- All venomous snakes shown, handled and displayed will, unless otherwise requested be those which are venomoid, which means that they have had their venom glands surgically removed. This is to protect handler, snakes and public from accidental bites in terms of "worst case" scenario. It is also in the snake's best interests that they be made "non-venomous" if being handled frequently and this reflects in the unrivalled exceptional condition of our regularly exhibited venomous species.
- Snakebusters are the only reptile show company in Australia with the expertise to have venomoid snakes and therefore only Snakebusters can offer a completely safe and risk free venomous snake show.
- Any other company's venomous snake shows will put you, your friends and your kids at risk of life-threatening venomous snake bite which at best will probably have serious peremenant health issues. There numerous such fatal and near fatal snakebite incidents yearly in Australia involving other snake handlers, but most are not reported by the media.
- We are the only reptile show outfit in Australia who do not use sticks, tongs and similar devices to torment venomous snake species for public displays.
- Because venomoid snakes only have two functional fangs (teeth), which are also relatively small in size, a bite from one of these snakes inflicts far less skin damage than a bite from a naturally non-venomous snake of similar size, which naturally has many sharp teeth in the mouth (e.g. python).
- Please note a number of business competitors have littered the internet with false claims and allegations about venomoid snakes. We have successfully taken action against some, but the nature of the internet makes it logistically not possible to action all false and misleading posts. However in summary these snakes do not regenerate venom and do not suffer pain as a result of the operation. The contrary is true. After many years of being devenomized, none have ever regenerated any venom gland (checked and rigorously tested by several means) or a drop of venom. Our snakes have been certified by a licenced veterinary surgeon as devenmomized on several occasions to the satisfaction of authorities in several states.
There have also been since mid 2008, many videos in circulation (including the internet) of the Snake Man Raymond Hoser forcing venomoids, including of the world's deadliest species, to bite him to prove that their bites have no venom and are totally safe and harmless and with the skin pricks, that the snakes still have teeth and fangs.
Fortunately, the circulation of these videoes have also stopped most of the ridiculous and malicious claims being made about the venomoids.
Click here for a Venomoid devenomized snakes FAQ.
Obvious risks non-venomoids - not Snakebusters.
- Due to the O H and S Act 2004, most reptile demonstrators do not now deal with venomous species.
- However, as a relevant note, all our competitors (using venomous reptile species) and/or their staff have been rushed to hospitals for serious venomous snakebites, including no less than 6 serious snakebite incidents in 2007 (and others in 2008-2012, including several fatal bites incurred during displays, with no less than 6 well known snake handlers being killed by their snakes in 2011 alone!).
- Snakebusters has a perfect safety record (no staff ever rushed to hospital for snakebites) and with venomoids there is zero risk of such ever occuring at a show or event.
- We accept no liability or responsibility in terms of persons who may see one of our shows and any actions they may take afterwards.
- This includes attempts by show participants or viewers to move, handle or catch other wild or captive reptiles, snakebites and other potential mishaps, physical or legal.
- Snakebusters and no one else, can guarantee safety of person/s at a reptile demonstration using venomous snakes that have not been surgically devenomized and issues a warning to this effect. Claims of "expertise" by handlers in terms of public events should be dismissed, noting that even the best handlers may get bitten when handling deadly snakes and on a regular basis such bites occur.
- Note that in early 2008, an experienced reptile demonstrator died from a snakebite from one of his "pet" snakes that had not been devenomized. Also note that sometime earlier in a separate incident, thieves stole a deadly snake from within a locked room at an exhibition. That snake was not devenomized and had a bite occurred, the owner of the snake would have been liable to be sued.
- Recent life threatening snakebites (usually needing anti-venom to save the life), involving licenced demonstrators and staff (from outfits who at times compete against Snakebusters for business) who do not use venomoids, have included the following: Simon Watharow (trading as "Snakehandler"), (rushed to hospital and needed anti-venom (AV) after a Tiger Snake bite), Sean McCarthy also trading as "snakehandler", who uses tongs to attack snakes and was recently carted to hospital for a Death Adder bite, John Deutscher (who worked with Watharow), a number of Death Adder bites and anti-venom and now no longer keeps snakes for obvious reasons, Glen Clapton at Healesville Sanctuary needed AV after getting chomped by a Red-bellied Black Snake, Byron Manning also at Healesville Sanctuary was similarly chomped by a Broad-headed Snake and rushed to hospital for a dose of anti-venom, Stuart Parker of Ballarat Wildlife Park was rushed to hospital in 2007 after a Death Adder bite, Chris Hay, carted off to hospital for serious bites a number of times, including bites from a King Brown and a Floodplain Death Adder, Neville Burns, chomped by a Black Snake, carted off to hospital and missing a finger from same, John Lucas of Educational Reptile Displays, was rushed to hospital in 2007 after being bitten by a Mulga snake when showing it to people at the Redlands Show and again shortly after by a Death Adder when showing people how "squishy" it's head was and the snake not surprisingly taking umbrage at the cruelty inflicted on it, Tom Parkin of a North Queensland wildlife park rushed to hospital after a Taipan bite in 2007, add to the list keepers at Australia Zoo (Queensland)(Taipan bite), no less than four near fatal bites in a decade and that's before one includes non-snakebite incidents such as Steve Irwin killed when illegally attacking a Stingray in 2006 and countless serious big cat attacks at the same place, Australian Wonderland (Sydney)(Jaffa snake bite, later had one stolen), Venom Supplies (South Australia) (at least four near fatal snakebites and a fatality involving a staff member), Bredl's Zoo (South Australia)(Taipan bite), Tony Harrison of the Gold Coast Queensland, who besides having several near fatal snake bites himself requiring rushed trips to hospital and anti-venom, he also nearly killed a member of the public after a venomous snake he illegally gave him bit him and nearly killed him, but he was not charged over the incident as he is well connected; and it is clear that use of non-venomoids is hazardous for all concerned. Worksafe Victoria have already stated (in March 2006) that non-venomoid snakes cannot legally be used in Victoria under the newly passed OH and S Act.
- Click the following link for a more extensive and up to date list of fatal and near fatal bites of snake handlers.
- Based on the Worksafe statement/s and the O H and S Act, venomous species shown outside a Snakebusters demonstration, or outside a locked and sealed cage in a zoo, are probably being shown illegally and if an accident occurs, both demonstrator and booking entity would probably be liable. In VCAT in 2015, Melbourne Zoo staff confirmed they had legal advice that use of snakes with venom for displays, even if in cages in a public display in a zoo is illegal if there is any way, shape or means that a determined person could break into the facility or cage and steal the animal and get bitten at the same time.
- All information and advice we give is given in good faith and based on decades of experience. It may not however be either correct and/or applicable to all circumstances and we accept no liability, legal or implied in terms of persons following our advice or any liability if people choose to deal with unsafe providers.
Warning: Reptiles are highly regulated in all Australian states.
- In most cases it is illegal to catch, keep, handle or interfere with any reptiles in any circumstances without written legal authority from the government.
- Due to the complexity of the laws and the frequency with which they change, any advice we give on such matters must only be regarded as 'tentative' at best.
- Persons intending having any contact with reptiles (in any way) outside of a snakebusters presentation should in the first instance seek binding legal advice from the relevant government authorities.
Reptile and wildlife removals including "call outs".
- Any booking cancelled after the seven day "cooling off" period is subject to a cancellation fee at our discretion. Under normal circumstances, this will be half the normal fee payable, which we levy to cover potentially missed bookings.
- For any cancellation within 2 days of the scheduled event, including if we arrive at an event when a cancellation has not been communicated to us, we shall charge the full booking rate, regardless of whether we actually do a display or not.
- Notwithstanding the preceding, we reserve the right to charge a cancellation fee of double the full amount we would have been paid, for any event that has cancelled and subsequently engaged another company or entity in any form of reptile or wildlife display at the event, even if we used our discretion not to levy a cancellation fee at the time we were advised of the cancellation (such as outside the 7 day cooling off period). The fee of double is payable to cover both the lost income from other potential bookings and any damage to our brands as a potential result of the use of our Intellectual Property (IP) and/or superior reputation in the promotion of the event at any stage. In addition, we also explicity reserve any and all other rights in terms of our intellectual property including to also sue for things like trademark infringement, damages, punitive damages, aggravated damages, corrective orders and anything else legally allowable, should our intellectual property be used by any person at any stage in any way improperly.
- Likewise (in terms of the above) in terms of the differential payment chargeable in the event a cancel fee of 50% or 100% was paid in terms of the same event in the absence of knowledge by us of another company or entity doing a reptile or wildlife display at the said event.
- Cancellation fees are payable within 7 days of the cancellation.
- We add costs payable for unpaid debt recoveries at our discretion.
- Any legal costs incurred during debt recovery are added to the amount payable either at the time or if need be after this as a "new debt owed".
- Any matter referred to the "Small Claims tribunal" Victoria or equivalent, shall have an added fee of $1,500 a day (or part thereof) added to the claim to cover potentially lost bookings due to potential time spent in court, lodging papers and the like and time spent at the tribunal, with an added 50 per cent loading on the original debt added as well.
- In other words any debt claim lodged at the "Small claims tribunal" or equivalent will be for an owed amount of at least $1,500 and 150 per cent of the booking or cancellation fee payable and owing.
- As a warning, Snakebusters has in the past successfully actioned entities and persons who have cancelled and/or not paid in bad faith for the full debt owed and/or unlawfully used our intellectual property!
- Please also note that there have been fatal snakebite incidents involving our clients or potential clients who have been unlawfully diverted from our business to unsafe inexperienced imitators and nothing here removes that risk to those who deal with these persons and entities.
- Snakebusters are not to be held responsible for the general conduct of persons at a venue or event and have no responsibility or liability for damages, thefts and other actions by such persons either of snakebusters materials or that owned and/or controlled by others.
- Snakebusters and all staff will at all times put the welfare of their animals first. This may involve altering or at "worst case" stopping presentations if it is determined that there is an unacceptable risk to any animals in any way. This may include "barring" or banning persons who have been determined "high risk" and our decisions in this regard are not subject to negotiation or dispute.
- If snakebusters terminate or alter a show in any way as a result of conduct of persons and/or unforseen event or circumstance, Snakebusters will not be liable for any damages or refunds.
- Snakebusters only allow photos for private purposes only. Any photos to be taken or used commercially, printed on websites or similar must be approved by snakebusters first. Under no cicumstances are any photos of snakebusters in any manifestation to be digitally altered in any way, except following written approval by snakebusters.
- Photos taken in schools and pre-schools can be used for in house purposes without permission so long as they are not used in any way that may in any conceivable way commercially harm snakebusters or any snakebusters staff.
- Snakebusters photos, photos taken of snakebusters reptiles and similar must not be used to promote other persons, other persons reptiles, other events not featuring snakebusters or any other such thing that may cause a non-involved person to be mislead in any way.
- Any event that books Snakebusters is allowed to use photos taken of Snakebusters for promotional purposes, as per the rules at: http://www.smuggled.com/kotabi4.htm.
- Under no circumstances are our images or images of us and our reptiles, and similar to be used to promote any other wildlife demonstrator, zoo or similar, or entities not controlled by us, including in any possible way, such as at a venue where we have appeared and an alternative animal, reptile or wildlife show may appear subsequently, for the obvious reason that we may be inadvertently associated with the other entity in some way.
- In the event that photos of Snakebusters and/or our reptiles are used to promote another wildlife displayer at an event Snakebusters have appeared at, Snakebusters reserves the right to charge for infringed IP, at the rate that would have been charged at the event had Snakebusters attended.
- Furthermore, Snakebusters reserves all rights in terms of infringed IP, especially in the face of continued infractions or those following any "cease and desist" demand and in the light of deliberate and serious IP breaches by less experienced reptile handlers in the period 2006 to 2012, and persons acting at their behest, not all of which we have actioned.
- Snakebusters accept that all equipment, boxes and the like will be subject to normal "wear and tear" and this is not an issue. However in terms of malicious, reckless or unacceptable damage, we seek rights to recover costs.
- In the event of theft or malicious or reckless damage to boxes, equipment, banners or any other material, Snakebusters reserves the right to levy recovery costs for "as new" replacement, including associated costs for sourcing, freighting and the like.
- In the event of theft of animals, or intentional killing of animals, snakebusters must by law report all such incidents within a reasonable time frame and will do so.
- In the event of theft or intentional killing of animals, the venue or booking person/s will be held liable for replacement costs to the following minimum scale, $300 per skink lizard, frog or terrapin, $1,000 per snake, crocodile or non-skink lizard, with a loading of $5,000 for albino's, leucystics, or scaleless reptiles and same for Green Pythons.
- Reptiles intentionally or recklessly injured at an event that die as a result (must be within 60 days), will be treated the same as in above paragraphs.
- Inductions: For bookings such as photo shoots, publicity events, corporate events, "meet and greets" and similar, we reserve the right to do an "induction" prior to commencement of the scheduled work to ensure an educational element to the booking and to make sure the relevant people are educated properly about reptile welfare, handling and if neccesary safety issues.
- Courses: All persons doing venomous snake catching, venomous snake handling or similar courses will be made to sign an indemnity or waiver of claim prior to commencing the course or they shall not be allowed to do the said course. Legal requirements in terms of the course, including species used will vary depending on the jurisdiction and any potential directives (legally binding) by government authorities.
Intellectual property, Defamation and similar.
- We do not like litigation as it is costly and time consuming and diverts our attention from our world leading conservation work and hence prefer people to simply do their business honestly and ethically.
False claims against Raymond Hoser and Snakebusters.
- For some years, a number of inexperienced imitators and others who stand to gain from the demise of Raymond Hoser and Snakebusters have waged sophisticated campaigns to attack and discredit our brands with a litany of lies and other attacks. Included have been no less than 36 bogus criminal charges laid by corrupt wildlife officers with an improper relationship to these businesses, all of which were thrown out of court in 2014 (twice) and again in 2015, when they were illegally relitigated. The government regulator which also competes against Snakebusters in the "wildlife business" and itself breaks the law regularly was ordered by Victoria's highest court to pay costs in 2014 and as of 2016 is facing a multi-million dollar payout.
© 2016, Snakebusters®, reptile party®, Melbourne, All Rights Reserved.


text:
Q: Transition an element after reintroducing it into the flow I know that is not possible to transition properties like display, position, visibility but how can one add a transition effect (over opacity in my case; working either on show and hide) AND being able to put a display: none on that element?
There's no need to transition: display .., but just that after it is set to block then the transition on opacity would start.
I thought I could cheat using transition: display 0s, opacity .3s but I can't manage to make it work.
Of course I could use tricks like setting height: 0; overflow: hidden; to hide my element but in my case I also need to remove the element from the flow (the element is position: fixed) and prevent TABbing on it's descendants and focusing hidden elements.
Is it using animations the only supported alternative?
No Javascript solutions, please; I believe the presentation should be a concern of CSS.

A: You can probably use CSS animation @keyframes. Note, it can add appearing animation, but won't do the disappearing part, as display:none will be applied instantly.

function show() {
  var el = document.getElementById("display");
  el.classList.remove("hide");
  el.classList.add("show");
}
.hide {
  display: none;
}

.show {
  display: block;
}

.animation {
  animation: fadeIn 2s;
}

@keyframes fadeIn {
  from {
    opacity: 0;
  }
  to {
    opacity: 1;
  }
}

  <input type="text" placeholder="input 1">

  <input type="text" placeholder="input 2">

<button onclick="show()">show</button>


text:
ANNABELLE 3 Casts Ed and Lorraine Warren's Daughter and Her Babysitter Who Will Be Terrorized
Movie Annabelle 3McKenna GraceMadison Iseman about 9 months ago by Joey Paur
There's two new big casting announcements for Annabelle 3 to share with you today. Captain Marvel and Gifted star Mckenna Grace has been cast in the role of Ed and Lorraine Warren's young daughter Judy. It's their daughter who becomes the target of the demonic doll in the story.
It was also revealed that Jumanji: Welcome to the Jungle star Madison Iseman has been cast as a babysitter who will be watching over Judy. As you might expect, Judy and the babysitter will both be terrorized by Annabelle as they are alone in the house.
The story "picks up with the Warrens bringing Annabelle to the place where it can really no longer wreak havoc, which is their artifact room. But, of course, it turns out she can also wreak havoc there. And she really awakens the evil within that room and they target the Warrens' 10-year-old daughter, Judy."
It was also teased that "Annabelle basically activates all the other haunted artifacts in that room. So, it's basically A Night at the Museum, with Annabelle!"
The upcoming Annabelle sequel sounds like it could be a really fun and scary flick! I really like the concept. I wonder how many more films they are going to squeeze out of this creepy-ass doll.
Source: THR, Deadline
First Details Revealed For ANNABELLE 3 Which Takes The Horror To Ed and Lorraine Warren
Patrick Wilson and Vera Farmiga Are Set To Star in ANNABELLE 3
James Wan Says ANNABELLE 3 Will Feel More Like a CONJURING Film Than the Other Spinoffs
ANNABELLE 3 Gets an Official Title and an Announcement Trailer
James Wan Shares First Photo From ANNABELLE: COMES HOME
Annabelle Is Unleashed in Spine-Tingling Full Trailer for ANNABELLE COMES HOME


So many things begin to slow down as a person ages. Usually, people perceive slowing down as a negative. But when it comes to the thyroid, Dutch investigators say that being too active is what is most likely to lead to depression.
The results of an eight year study shows that a busy thyroid in seniors can lead to an increased risk for depression. It was already known that an extremely overactive (hyperthyroidism) or a markedly underactive (hypothyroidism) thyroid was connected to mental health conditions.
The thyroid gland, located in the neck, produces hormones that govern metabolism and balances the body's reactivity with other hormones. Thyroid activity is stimulated by TSH (thyroid stimulating hormone) sent out from the pituitary gland. Therefore, if you measure the amount of TSH you can get a pretty good handle on the activity level of the thyroid. More TSH equals a busy thyroid; less TSH indicates a more sluggish thyroid.
Researchers from the Erasmus Medical Center in Rotterdam, the Netherlands, measured the TSH of 1,503 older adults. The average age of the study participants was 70 years. Investigators used questionnaires to find out how subjects were feeling and used them to assess for depression. The subjects did not exhibit signs of depression during the initial interview, but did so over the eight year course of investigation.
Participants were placed in one of three groups according to their TSH levels. Investigators then compared TSH levels against symptoms of depression. They found that the more active the person's thyroid, the more likely it was that they would develop symptoms of depression. People with the most active thyroids experienced the strongest symptoms of depression.
Dr. Marco Medici was a co-author for the study. He said that these findings were new insofar as they revealed that older people whose thyroid was operating on the upper end of normal range had a notably higher risk for depression versus people with less active thyroid that was still in normal range. Medici said that the data indicates that even minute changes in thyroid activity and functionality could make a person vulnerable to some of the same mental health impacts as people diagnosed with hyper or hypothyroidism.
The study holds implications for treatment of thyroid and for treatment of depression. Measuring TSH could become part of depression testing and regulating TSH might become part of treatment for depression. Patients with mild hyper or hypothyroidism could be made aware of their risk for depression and be given tools for combating this unpleasant side effect. This is one instance where slowing down with age is a good thing.