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East Sedan Chair House
Queen's Parade Place
BA1 2NN
N/A Bedrooms
One of only 2 remaining Sedan Chair Houses in Britain
properties@lpoc.co.uk
Situated in the heart of Bath, an unusual and historic Grade II Listed, detached, single storey building of approximately 100 sq. ft. built by John Wood the Elder c1734. Coursed limestone construction beneath a pavilion roof. Connected for electricity and water. Freehold.
This is one of only 2 Sedan Chair Houses remaining in Britain:
Britain's Only Surviving Sedan Chair Houses
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Currently let on a 4-year lease expiring on 09/05/2022 (with 2-year break clause on 09/05/2020)
Rental income: £4,500 (potential of £9,000/annum)
The property is exempt from business rates.
Bath, with a population of some 88,000, is situated approximately 97 miles west of London and 11 miles east of Bristol
The property is situated on the junction with Gay Street in the centre of Bath
Shopping facilities are available locally and to a greater extent in Bristol city centre, along with an excellent selection of cafés, bars and restaurants
Recreational facilities are available locally in Royal Victoria Park and at Bath Recreational Ground
Road communications are via the A4 and A36
for sale £150,000
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Ah yes, Geissele … a name synonymous with Elite Military Contracts, Angelic trigger units, Rails systems Tony Stark would be proud to call his own, and well… let's be honest, Stout pricing. But you'll never hear someone disassociate their brand with the word quality. If you're willing to pay, they will deliver the utmost to you.


text:
Prashant K. Verma
All India Institute of Medical Sciences, Rishikesh, India
Ibtessam R. Hussein
Xiaojun Sun
St. Jude Children's Research Hospital, United States
CASE REPORT article
Front. Genet., 20 August 2018
Sec. Genetics of Common and Rare Diseases
Volume 9 - 2018 | https://doi.org/10.3389/fgene.2018.00275
Prenatal Diagnosis of Recurrent Distal 1q21.1 Duplication in Three Fetuses With Ultrasound Anomalies
Xiuqing Ji1†, Qiong Pan2†, Yan Wang1, Yun Wu1, Jing Zhou1, An Liu1, Fengchang Qiao1, Dingyuan Ma1, Ping Hu1* and Zhengfeng Xu1*
1State Key Laboratory of Reproductive Medicine, Department of Prenatal Diagnosis, Affiliated Obstetrics and Gynecology Hospital with Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China
2Laboratory of Clinical Genetics, Department of Prenatal Diagnosis, Huai'an Maternal and Child Health Care Hospital, Huaian, China
Background: The phenotype of duplication of 1q21.1 region is variable, ranging from macrocephaly, autism spectrum disorder, congenital anomalies, to a normal phenotype. Few cases have been reported in the literature regarding prenatal diagnosis of 1q21.1 duplication syndrome. The current study presents prenatal diagnosis of 1q21.1 duplication syndrome in three fetuses with ultrasound anomalies.
Case presentation: Three fetuses from three unrelated families were included in the study. The prenatal routine ultrasound examination showed nasal bone loss in Fetus 1 and Fetus 3, as well as duodenal atresia in Fetus 2. Chromosomal microarray analysis was performed to provide genetic analysis of amniotic fluid and parental blood samples. The CMA results revealed two de novo duplications of 1.34 and 2.69 Mb at distal 1q21.1 region in two fetuses with absent nasal bone, as well as a maternal inherited 1.35-Mb duplication at distal 1q21.1 in one fetus with duodenal atresia.
Conclusions: The phenotype of 1q21.1 duplication syndrome in prenatal diagnosis is variable. The fetuses with nasal bone loss or duodenal atresia may be related to 1q21.1 duplication and chromosomal microarray analysis should be performed.
Individuals with 1q21.1 duplication (OMIM 612475) are reportedly associated with a spectrum of macrocephaly, autism spectrum disorder, dysmorphic features, and congenital anomalies. In recent years, the application of CMA allows for more patients with 1q21.1 duplication to be revealed (Brunetti-Pierri et al., 2008; Mefford et al., 2008; Rosenfeld et al., 2012; Soemedi et al., 2012; Dolcetti et al., 2013; Verhagen et al., 2015; Bernier et al., 2016; Buse et al., 2017; Wang et al., 2017). Highly diverse inter- and intrafamilial outcomes were observed among patients harboring 1q21.1 duplication, from almost normal to severely affected (Brunetti-Pierri et al., 2008; Mefford et al., 2008; Dolcetti et al., 2013; Buse et al., 2017).
Chromosomal region 1q21.1 is structurally complex with many SDs that make it prone to NAHR (Sharp et al., 2005; Mefford et al., 2008). Some scholars believed that the chromosome 1q21.1 region can be subdivided into two distinctive regions (Rosenfeld et al., 2012; Verhagen et al., 2015; Wang et al., 2017). The proximal region, which is flanked by SDs, extends recurrent BPs from BP2 and BP3 (spans about 200 Kb), and the distal region extends from BP3 to BP4 (spans about 1.35 Mb). Individuals with the proximal duplication had variable phenotypic features, with the most common features: intellectual disability (ID), dysmorphic features, and behavioral problem (Rosenfeld et al., 2012). More patients with distal duplication were reported and manifested ID, autism, congenital heart disease (CHD) (e.g., tetralogy of Fallot), macrocephaly, and mild dysmorphic features (e.g., frontal bossing and hypertelorism) (Brunetti-Pierri et al., 2008; Mefford et al., 2008; Rosenfeld et al., 2012; Dolcetti et al., 2013).
Due to the limited number of cases being reported, the incidence of this disease has not been reported in the population. Brunetti-Pierri et al. (2008) reported that 1q21.1 duplication was detected in 17 out of 16557 (0.103%) patients from a wide range of referring diagnoses, including mental retardation, autism and/or congenital anomalies. Mefford et al. (2008) identified nine persons with a recurrent 1.35-Mb duplication of 1q21.1 in 5218 (0.172%) patients with mental retardation, autism spectrum disorder and other variable features. Duplications at 1q21.1 were rare in control populations, with an incidence of 0.027% (Soemedi et al., 2012; Dolcetti et al., 2013).
Up to now, only two prenatal cases with 1q21.1 duplication were reported in literature (Liao et al., 2012; Verhagen et al., 2015). To provide a better understanding of this submicroscopic imbalance in prenatal diagnosis, we present our study on prenatal diagnosis of recurrent distal 1q21.1 duplication in three fetuses with ultrasound anomalies.
Case 1 was a fetus with absent fetal nasal bone detected by routine ultrasound examination during the second trimester (Figure 1A). Down's screening was at high risk of chromosome 21 (1/215). After genetic counseling, amniocentesis was performed at 24 weeks of gestation. The parents were non-consanguineous and parental blood samples were drawn. Family history was unremarkable. Case 2 was a fetus identified with duodenal atresia during the second trimester ultrasound examination (Figure 1B). The rest of the fetal morphology was normal. After genetic counseling, amniotic fluid sample was obtained at 25 weeks of gestation and parental blood samples were drawn. The mother's phenotype is completely normal and she had no significant medical, surgical, or family history. Case 3 was a fetus identified with nasal bone absence by prenatal ultrasound morphology scan. After genetic counseling, amniotic fluid sample was collected at 26 weeks. Family history was unremarkable. Parental blood samples were collected. Clinical data of three fetuses are listed in Table 1 and Figure 2.
FIGURE 1. (A) Fetus with absent nasal bone. (B) Fetus with duodenal atresia.
TABLE 1. Summary of clinical data and genomic information on three fetuse.
FIGURE 2. Pedigree of three families in this study. I, parent; II, offspring; , male; , female; , induced labor female fetus; , induced labor male fetus; , dup 21.1 patient without clinical symptoms; , aborted fetus.
Amniotic fluid cell sample and peripheral blood of the parents were collected for cell culture followed by karyotyping. GTG-banding was performed according to a standard protocol. Karyotypes were determined from G-banding analysis using standard protocol according to the ISCN 2009 nomenclature.
Genomic DNA was extracted from uncultured amniotic fluid or blood cells, using the QIAamp DNA Mini Kit (QIAGEN, Hilden, Germany). Genomic DNA was examined by Human cyto12 SNP-array scanning (Illumina, United States), which comprised about 300,000 SNPs across the whole genome. SNP-array experiments were carried out as previously described (Hu et al., 2013) and molecular karyotype analysis was performed by KaryoStudio V 1.3.11(Illumina). Parental blood samples from each fetus were also obtained for the microarray analysis.
Karyotype analysis showed that all the fetuses and their parents had normal karyotype. The CMA results of Fetus 1 and the parents revealed a de novo 1.34-Mb duplication at 1q21.1q21.2 containing nine OMIM genes (chromosome position: 146476526–147820342). The CMA results of Fetus 2 and the parents revealed a maternal inherited 1.35-Mb duplication at 1q21.1q21.2 encompassing nine OMIM genes (chromosome position: 146476526–147826789). The CMA results of Fetus 3 and the parents revealed a de novo 2.69-Mb duplication at 1q21.1q21.2 encompassing 14 OMIM genes (chromosome position: 146510112–149205098) (Table 1 and Figures 3, 4). We offered detailed genetic counseling to the couples and informed them about the variable phenotypes of the 1q21.1 duplication syndrome. All the three couples ultimately chose to terminate the pregnancies.
FIGURE 3. Results of CMA in three 1q21.1 duplication fetuses. (A) The original version. (B) The enlarged version. (C) Normal chromosome 1.
FIGURE 4. The positions of 1q21.1 duplication cases reported in prenatal diagnosis. At the top of the figure is an ideogram showing chromosome band 1q21.1 with genomic coordinates corresponding to the hg19 build of the human genome. Gray bars represent clusters of SD blocks BP3 and BP4 that contain the BPs of the recurrent rearrangements. Plots (blue shading) show the recurrent 1q21.1 duplications found in subjects reported in prenatal diagnosis.
In this study, we report three prenatal cases of distal 1q21.1 duplication syndrome. The results of CMA revealed two de novo duplications of 1.34 Mb and 2.69 Mb at distal 1q21.1 in Fetus 1 and Fetus 3 with absent nasal bone, respectively, and a maternal inherited 1.35-Mb 1q21.1 duplication in Fetus 2 with duodenal atresia.
Phenotypic features described in association with 1q21.1 duplication are highly variable (Brunetti-Pierri et al., 2008; Mefford et al., 2008; Verhagen et al., 2015). Many patients with the 1q21.1 duplication have been described, yet only two cases were reported in prenatal setting. Verhagen et al. (2015) reported a fetus with distal 1q21.1 duplication (2.6 Mb, 145243316–147814694, Figure 4) with dilated ventricles, a ventricular septal defect, and dilated main pulmonary artery and aorta. Liao et al. (2012) described a fetus with proximal 1q21.1 duplication (258 Kb, 144337316–144595988, Figure 4) with bilateral polycystic kidney, oligohydramnios, ventricular septal defect. In this study, we describe three fetuses with distal 1q21.1 duplication spanning from BP3 to BP4 in the prenatal diagnosis. Fetus 1 and Fetus 3 with absent nasal bone exhibited 1q21.1 duplication of 1.34 Mb (146476526–147820342) and 2.69 Mb (146510112–149205098), respectively. Fetus 2 with distal 1q21.1 duplication (1.35 Mb, 146476526–147826789) exhibited the feature of duodenal atresia.
Nasal bone absence is an important marker during the first or second trimester in prenatal screening for trisomy 21 (Sonek et al., 2006; Persico et al., 2012). The incidence of trisomy 21 in fetuses with absent or hypoplastic nasal bone varied widely, ranging from 26 to 77% (Moreno-Cid et al., 2014). A few cases with absent nasal bone were reported to be associated with the CNV. Brisset et al. (2015) reported duplication of 1q12q21.2 of 5.8 Mb associated with deletion of 16p11.2 of 545 Kb in a fetus exhibiting an absent nasal bone. Chen et al. (2017) reported an absent nasal bone fetus with a 2.752-Mb duplication at 4q11, a 1.949-Mb duplication at 4q13.2, and a 1.65-Mb deletion at 5q13.2, exhibiting no other apparent phenotypic abnormality. In our study, two 1q21.1 duplication fetuses displayed absent nasal bone. Therefore, the phenotype is not only related to Down's syndrome, but also associated with CNV. It is suggested that CMA may be offered to fetuses with absent nasal bone in prenatal diagnosis.
The long-term prognosis of fetal digestive tract malformation depends on whether it is accompanied by chromosomal abnormalities or whether it has other malformations (Stoll et al., 2015). The typical double bubble sign, which strongly indicated duodenal atresia (Pariente et al., 2012), was found in Fetus 2 in our study. When duodenal atresia is detected prenatally, it is usually associated with a high incidence of trisomy 21 (Choudhry et al., 2009; Yang et al., 2017). Stoll et al. (2015) summarized that in the 728 cases of trisomy 21, 216 cases (30%) were identified with duodenal atresia. However, duodenal atresia has not been reported in cases of 1q21.1 duplication previously. This is the first prenatal case of distal 1q21.1 duplication exhibiting duodenal atresia.
The overlapping region of the recurrent 1q21.1 duplication in the three fetuses included nine OMIM genes: PRKAB2, FMO5, CHD1L, BCL9, ACP6, GJA5, GJA8, NBPF24, and GPR89B. The abnormal expression of GJA5 and its flanking gene GJA8 have been previously reported to be associated with CHD (Soemedi et al., 2012; Dolcetti et al., 2013; Verhagen et al., 2015). Dou et al. (2017) speculated that CHD1L can promote neuronal differentiation in hESCs and play an important role in nervous system development. Kimura et al. (2015) explored BCL9 gene, and suggested it may be a susceptibility gene of schizophrenia. The two genes might associate with nervous system problems in 1q21.1 duplication of postnatal patients. Nevertheless, no genes within the overlapping region were found to be associated with duodenal atresia.
Many postnatal cases with 1q21.1 duplication have been identified with mental retardation, autism, multiple congenital anomalies, and other psychiatric disorders. A subset of individuals is clinically unaffected (Brunetti-Pierri et al., 2008; Mefford et al., 2008; Dolcetti et al., 2013; Buse et al., 2017). In our study, the 1q21.1 duplication in Fetus 1 and Fetus 3 occurred de novo, and Fetus 2 was maternal inherited. The penetrance for distal 1q21.1 duplication was reported to be 29.1% (Rosenfeld et al., 2013). The incomplete penetrance and variable expressivity of the duplication syndrome pose challenges for counseling regarding prenatal diagnoses, especially for the syndrome associated with neurodevelopmental phenotypes that cannot be ascertained prenatally. Therefore, in the prenatal genetic counseling session, comprehensive and detailed information about the estimates for penetrance and the range of possible phenotypic outcomes of the syndrome should be offered to the prospective parents. In this study, after comprehensive genetic counseling, the couples ultimately chose to terminate the pregnancies. Routine ultrasound screening during the second trimester of pregnancy is performed between 22 and 28 weeks of gestation in China. Therefore, amniocentesis was carried out late in these cases. In China, it is legal to induce labor before 28 weeks of gestation if the fetus is identified to be with severe structural malformation or pathogenic chromosomal abnormalities. This study is a retrospective study, so it is regretful that the pregnant women and their families have refused the autopsy. However, we carried out the follow-up study and no obvious abnormalities were observed in the appearance of the three fetuses after termination of the pregnancies.
In summary, we reported the prenatal diagnosis of distal 1q21.1 duplication in three fetuses with absent nasal bone or duodenal atresia. The phenotype of 1q21.1 duplication is highly variable prenatally, like postnatally. Combined with ultrasonic examination, the application of CMA will improve the diagnosis of recurrent rearrangements of 1q21.1 in fetuses. Identification of additional affected fetuses with similar rearrangements of chromosome 1q21.1 is needed to provide further insights into the pathogenesis of 1q21.1 duplication syndrome.
The study was reviewed and approved by the ethical committee of the Affiliated Obstetrics and Gynecology Hospital with Nanjing Medical University in China. Written informed consent to participate was obtained for all participants or their guardians before collecting samples of amniotic fluid and blood. Written informed consent was obtained from the patient for publication of this research.
All data generated or analyzed during this study are included in this published article.
XJ and QP wrote the paper and carried out molecular genetic studies. ZX and PH helped to draft the manuscript. YaW and JZ conducted genetic counseling. YuW conducted ultrasonic testing. AL, FQ, and DM carried out the laboratory work. All authors read and approved the final manuscript.
This work was supported by the National Natural Science Foundation of China (81671475 and 81602300), the Project on Social Development of Jiangsu Province (BE2015614).
The reviewer IRH and handling Editor declared their shared affiliation.
We would like to thank the pregnant women and their family members who contributed in this study.
BPs, breakpoints; CMA, chromosomal microarray analysis; CNV, copy number variant; NAHR, non-allelic homologous recombination; SDs, segmental duplications.
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Keywords: recurrent distal 1q21.1 duplication, prenatal diagnosis, chromosomal microarray analysis, nasal bone loss, duodenal atresia
Citation: Ji X, Pan Q, Wang Y, Wu Y, Zhou J, Liu A, Qiao F, Ma D, Hu P and Xu Z (2018) Prenatal Diagnosis of Recurrent Distal 1q21.1 Duplication in Three Fetuses With Ultrasound Anomalies. Front. Genet. 9:275. doi: 10.3389/fgene.2018.00275
Received: 20 April 2018; Accepted: 05 July 2018;
Published: 20 August 2018.
Prashant Kumar Verma, King Abdulaziz University, Saudi Arabia
Ibtessam Ramzi Hussein, King Abdulaziz University, Saudi Arabia
Xiaojun Sun, St. Jude Children's Research Hospital, United States
Copyright © 2018 Ji, Pan, Wang, Wu, Zhou, Liu, Qiao, Ma, Hu and Xu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Ping Hu, njfybjyhuping@163.com Zhengfeng Xu, zhengfeng_xu_nj@163.com

redpajama_set_name: RedPajamaCommonCrawl


Corsini Water Fountain is rated 5.0 out of 5 by 1.
Rated 5 out of 5 by Elyse11 from Beautiful fountain This piece is much nicer in person than I expected from the photos. It is beautifully made and is a classic garden ornament. Definitely recommend.
If the fountain was not placed against a wall, does the back look finished and smooth?
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Will this foundation withstand freezing temperatures for the Dallas TX area?
Thank you for your interest in the Corsini Water Fountain. This item can be used in Dallas.
Thank you for your interest in the Corsini Water Fountain. This fountain is made of premium-quality stone.
Can this fountain be hooked up to a water supply or manual fill only?
Thank you for your interest in the Corsini Water Fountain. This item does not have a connection for a water supply.
Can this fountain be converted to solar power?
Thank you for your interest in the Corsini Water Fountain. We do not offer a way to convert this light to solar power. We sincerely apologize for any inconvenience this may cause.
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The Corsini does need to be plugged into an outlet.


According to the article entitled, "When Music Becomes Your Medicine" by Bart Astor, "Music therapy has been around for a long time — Hippocrates was known to have played music for his patients as early as 400 B.C. — but only recently became a recognized medical discipline with board certification.
Our blog this week honors Gardens of Daphne volunteer Patrick Kenny. Mr. Kenny delights the residents with his harmonica tunes and brightens their days. As there is a delightful tune played on the harmonica called the "Missippi Mud"…we are including Gardens of Daphne resident Shirley Hartley's recipe for Missippi Mud. Mr. Kenny…look for the Gardens of Daphne to be fixing up a sweet treat just for you! Thanks for your time and dedication to bring joy to all the residents and staff at the Gardens of Daphne.
Preheat oven to 350 degrees. In mixing bowl, beat butter and sugar until creamy. Add eggs, one at a time, beating thoroughly after each addition. Sift together the flour and 1/3 cup cocoa. Fold this into the creamed mixture. Add pecans and vanilla. beat well. Pour into greased and floured 9×13-inch pan. Bake 30 to 35 minutes. Sprinkle top with marshmallows. Bake until marshmallows are melted and starting to turn brown (about 10 minutes). Remove from oven and cool in pan about 30 minutes. Icing: Melt butter in saucepan. Sift together powdered sugar and cocoa. Stir sugar mixture into butter along with nuts and milk. Spread over cake.
Elizabeth Andrew once said that "volunteers do not necessarily have the time…they have the heart." With that being said I wanted to shine light on one of our many volunteers that brighten our days at Great Oaks Management. Ellen Dewberry has been volunteering at the Gardens of Eufaula since 2010. She brightens the days of our residents and shares the word with Bible Study on Wednesday afternoons. Mrs. Dewberry is one of our shining stars! In honor of her sweetness we are going to share her delicious recipe for Turtle Cake! Thank you Ellen Dewberry for your kindness and your servant's heart. We at Great Oaks Management love our volunteers who are always being willing to share!
Mix cake mix according to package directions. In 9 X 13 inch pan that has been greased and floured, pour ½ batter. Bake for 15 minutes at 350 degrees. While this is baking unwrap caramels. Put in bowl and add the butter and milk. Microwave one to two minutes until melted. When cake is done, pour mixture over cake. Sprinkle chocolate chips on top of that. Pour rest of batter over this and bake for 20 more minutes.


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More than 140 of some the world's most influential CEOs will be distinguished guests of the French President, Prime Minister, and members of the government at the Palace of Versailles on Monday January 22, 2018.
The agenda for this day of discussions will focus on the government's work to transform the French economy through a series of reforms already well underway, including moves to introduce more flexibility into France's employment market and build a more business-friendly tax environment. Also on the schedule will be opportunities to meet key figures in the French business world.
The event will include bilateral talks and workshop sessions on topics such as social change, the economic outlook, forthcoming reforms, and France's role as an innovation powerhouse, startup haven and talent hub.


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avocations. In 1657—not ten years after he had been called to the bar, Monk recommended him to Cromwell for the office of Judge, as being a very honest man and a good lawyer.' Stair's acceptance of this office seems to Mr. Mackay a thing requiring excuse. In our judgment it was one of the most justifiable steps in his somewhat shifty public life. Nor do we think it worth while to defend a course of which an example was set by such men as Hale in his own profession, and Blake in another. Far more questionable was his conduct under Charles. He was knighted immediately after the Restoration, and included in the first Commission of Scottish Judges. But in 1662 a Declaration was imposed on all persons in offices of trust. This measure was aimed directly at Presbyterians. The declarant affirmed solemnly the illegality of all leagues, covenants, and gatherings in the late troubles ; 'and particu'larly, that those oaths, whereof the one was commonly called "" The National Covenant" (as it was sworn and explained in
the year 1638 and thereafter), and the other entituled "A 6" Solemn League and Covenant," were and are, in themselves
unlawful oaths, and were taken by and imposed upon the subjects of this kingdom against the fundamental laws and liberties
of the same.' Stair hesitated. His family was Presbyterian. He himself had all his life been a Presbyterian. "In the late
troubles' he had for two years borne arms for Christ's • Crown and Covenant.' He had, at one time, resolved to resign; but a slight concession from those in power sufficed to overcome his scruples. Lauderdale, who seems to have had as much liking for Stair as it was in his nature to have for any man, and who doubtless appreciated the value to the administration of Stair's character and abilities, stood his friend. He was summoned to London, and admitted to an interview with Charles, who possibly may have remembered with favour the secretary of Breda and the Hague. The result was a permission to accompany his signature of the Declaration with the verbal statement, that he was content to declare against ' whatever was opposite to his Majesty's just right and pre' rogative. These words are no real qualification of the terms of the Declaration, and it is difficult to believe that any mind can have regarded the utterance of them as other than a farce.* To such paltering with conscience we prefer the frank
* Very different from the qualification with which Burley took the test of drinking the health of the Primate of St. Andrews in Niel Blane's Change House — May each prelate in Scotland soon be as the 'Right Reverend James Sharpe.' Well might Bothwell say, 'I don't know what the devil the crop-eared Whig means.'
readiness of Lauderdale to sign a cartfull of such oaths before he would lose his place,
Stair was created President of the Court of Session, and made a member of the Privy Council in 1671. He held these offices for ten years—years during which, in the calm judgment of Hallam, the wickedness of the administration can find no parallel in modern history. For this Mr. Mackay proposes no defence; Mr. Graham adopts the defence stated by Stair himself in his " Apology,' which is simply that he did not approve of severity against those who suffered for serving . God in the way they were persuaded ;' that he did what he • durst to save them. The defence is not very successfulespecially when we consider the small result of his exertions. The distinction between commissions granted for the performance of necessary public duties and those which relate to
councils for establishing usurped power or burdening the • people,' by which Stair justified his holding office urder Cromwell, cannot avail him in this matter. Lauderdale was then carrying out his scheme of subverting the Constitution and governing Scotland by the Privy Council, without a Parliament; and everyone who sat with him in the Privy Council must be held responsible for the guilt of that scheme. No one would impute to Stair the malignity of the apostate Sharpe, or the pleasure in human suffering which showed itself in the dark nature of James ; but a dislike to witness the infliction of torture was a merit which he shared with the majority of his colleagues, and his preference for moderate counsels was only evinced by absence or silence. By the practice of such prudential arts no man can obtain exoneration from whatever blame may attach to the government of which, from motives of ambition or interest, he consents to be a member.
But the time had now come when caution and moderation could no longer avail. The Duke of York came to Scotland as Commissioner in 1679, animated, even then, by that determination to raise up Popery which in the end cost him his crown. It was soon apparent that any such design would be opposed by all but the most subservient of Scottish statesmen. Stair, at his first interview with the Duke, gave offence by welcoming him to an entirely Protestant country. He filled up the measure of his iniquity by carrying in Parliament an addition to the Test Act of 1681, defining the Protestant religion as the religion contained in the Confession of Faith
recorded in the first Parliament of James VI. He tells us that his object was to provide the safest hedge against • Popery ;' and this object was perfectly apprehended by
James. Accordingly, Stair on going to London, either to obtain permission to take the test with a qualification, as he had done the Declaration of 1662 ; or, as some have said, with the view of securing for his more complaisant son the place which he foresaw he himself would have to resign, was, at the instance of the Duke of York, refused an audience of the King; and a new Commission was issued in which his name did not appear. Stair assures us he would not have signed the test. Why a man who had signed the Declaration of 1662, and had been for ten years a member of the Privy Council, should have stickled at this test we are wholly unable to understand. But it is unsafe to pronounce judgment on matters of conscienceespecially when the consciences are those of Scottish statesmen of the seventeenth century. The main fact is, that Government never offered him the chance of signing. To have done so would have been a farce. His ruin was determined on. Moderation, not unlike his own, had brought destruction on Argyle. The President's declared hostility to Popery was worse than moderation. His dismissal came from the same cause which, a few years later, raised Perth and Melfort over Queensberry; and which in England led to the downfall of the Hydes--the resolve of James to have in his service no minister who would not do his bidding even in the matter of religious profession.
Stair retired to the country, but was not allowed to enjoy his retirement. The eye of the tyrant was upon him. In 1662 Claverhouse was sent to urge on the persecution in Wigton and Galloway. Of course, he found cause of offence in everything done by the fallen President. It is half melancholy, half ludicrous, to read Stair's appeals to Queensberry, imploring favour, protesting loyalty, and remonstrating against being
disquieted' because his wife won't attend the parish church, which, he plaintively adds, ' I cannot help'-an inability easy of credence if the lady had any likeness to the mother of the Bride of Lammermoor. * At last, acting on a friendly hint from Sir George Mackenzie, he fled to Holland.
At Leyden—fit refuge for an exiled scholar-Stair found a
* Mr. Mackay's biographical enthusiasm prompts him to stand up for Lady Stair. But he might have remembered that she is thus described by one of her descendants : 'In Lady Ashton the character
of our great-great-grandmother seems in many respects more faith*fully delineated, or at least, less misrepresented. She was an ambi* tious and interested woman, of a masculine character and under
standing. Letter from Mr. Dalrymple Elphinstone in the Introduction to the Bride of Lammermoor.'
declare fact that the very time enjoyecord Justice Clerkers. He
society, composed of the most eminent and learned men in Europe, ready to soothe his six years of banishment. Of his life there little is known. He gave himself to literary pursuits; he supported, in a languid way, the enterprise of Argyle; while resting his hopes, we can readily believe, on a very different deliverer. He, least of all men, was likely to have been led away by the proverbial credulity of exiles. He was recommended by Fagel to the notice of William, who soon saw and valued his cool sagacity. He entered eagerly into William's great design, professing himself willing to venture his head, his own and his children's fortunes, in such an undertaking—a declaration the magnanimity of which is somewhat impaired by the fact that the family estates were perfectly safe in any event, being at that very time enjoyed by his eldest son, serving James as Lord Advocate and Lord Justice Clerk. But William could not afford to look closely into such matters. He knew Stair was able; he had reason to believe him willing to serve the good cause. He, therefore, honoured him with much confidence, and took him over to England in the · Brill.'
Here Stair's work as a statesman begins. He is said, indeed, to have shared the counsels of Monk before the march into England which restored the monarchy. But, with this exception, he had hitherto lived the life of a mere lawyer, avoiding, even to the disregard of duty, any part in state affairs. To such a course he had been led partly by timidity, partly because he disliked the governments he continued to serve. Both causes were now removed. His political views were in accord with the new order of things; there was no longer room for timidity: the only hope of safety to him or his lay in the stability of William's throne. Even now, however, the part which he took was not a public one. He lived in a beautiful villa on the banks of the Thames belonging to the widow of his old patron Lauderdale, and guided the deliberations of William on Scotch affairs by his experience and sagacity. He was, in the crisis of the Revolution, the confidential adviser Carstairs afterwards became. And, in truth, the sagacity which directed William in these things must have been sagacity of no common order. If, as there is every reason to believe, Stair suggested the mode in which the Convention which was to meet at Edinburgh should be summoned-in righteous disregard of existing laws; if, by his advice, nobles who had been deprived of their honours by the tyranny of the Stuarts were invited to resume their seats in Parliament; if, by his advice, the franchise was so extended that none but Papists were excluded from the vote; if he had any share in William's letter
h character ; Ecclesiastical walifficulty: Winduced to
to the Convention when it did assemble, and in the private instructions sent to the friends of the Government, in which we see not only a statesmanlike view of the position, but an intimate and accurate knowledge of Scotch parties and of the Scotch character; then few advisers have ever given wiser counsel to a prince. Ecclesiastical matters presented, perhaps, the most serious and the most lasting difficulty. William was undoubtedly desirous that the Scotch should be induced to accept a moderate form of Episcopacy. The establishment of Presbytery in Scotland made every Scotch Episcopalian a Jacobite, and was, moreover, in the highest degree distasteful to English churchmen, high and low alike. Nor is it uncharitable to suppose that a prince as greedy of power as any who have ever governed England may have had some preference for a form of Church government which, to say the least, has always been associated with the ascendancy of the Crown. Stair, knowing Scotland, knew the maintenance of Episcopacy to be impracticable. Aided probably by Carstairs, he had little difficulty in bringing William to this opinion. But a further and most important object was that William should be saved from the unpopularity sure to be incurred by him in England were he to countenance the overthrow of Episcopacy in the North. The matter must be decided before he could have any say in it, or any title to interfere. Stair effected this by prevailing upon the managers of the Convention to insert a clause in the Claim of Right declaring Episcopacy an insupportable institution, odious to the nation, which must be abolished. William, therefore, if he accepted the Crown of Scotland at all, had no choice but to accept it on a contract of which this was the first condition.
It seems to have been undetermined whether Stair should be restored to his place as President, then held by Sir George Lockhart. In his . Apology' he says he would not have taken the place while Sir George lived; adding, frankly enough, 'nor had I any doubt but that the King would have provided me as well as by it.' The murder of Lockhart in March 1689 removed all difficulty; and Stair thus writes, with a certain half-sincerity, as to his own feelings at the time: "That shamne'ful murder of Sir George Lockhart touched the King much, • and made him say to me he saw it was necessary that I should • resume my place again, which I was willing, though it was 'my right, he should continue to enjoy, being younger and abler to endure the toil than I.'
Accordingly he was re-appointed President of the Court of Session, and held that office till his death in 1695. These
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Buying a brand new car is quite tricky, especially for people who barely know what to look for in a particular type of vehicle. The features, speed and maximum capacity are just few of the many factors to consider when purchasing an automobile. Of course, you also need to check other important elements like durability, availability of spare parts and costs. In order to get the right vehicle for you, check out these simple and easy-to-follow new car buying tips.
The very first thing that you must do before buying a car is to research about it. Search the Internet regarding valuable information about the particular brand and model of the vehicle that you wish to own. Check its current selling price in order to get the best value in exchange for your money. It is also good to know the price range. This will help you not to overspend on a particular product that you can get at a relatively cheaper price. Be sure to compare one price with the other possible options. Moreover, it also gives you the power to negotiate with the sellers.
After researching the particular brand and model of the car you want, select the best deal possible. Choose the product with the lowest price without compromising durability, value and quality. Of course, do not forget to negotiate. The standard retail price of a vehicle is usually marked up, so negotiating with the dealer can actually lower its price. Thanks to the stiff competition in the automobile industry in recent years, these companies are offering a wide variety of special rebates and incentives. Check for the true market value of whatever vehicle you like before purchasing it.
Your satisfaction as a customer is always the top priority here, so be sure to buy the vehicle that you really need and want. Consider the color, options and trim level of the automobile. Furthermore, consider the model as well as the brand that fit your lifestyle. Of course, people do not wish to drive cars that do not look good on them.
Before buying a vehicle, make it sure that you test drive it. Doing this can give you a taste and a preview of what you are about to buy. You can also trade in your old car to reduce costs. Before sealing a deal, make sure that you have asked for the lowest price possible. Double-check documents and other important papers before signing them. Examine your newly purchased vehicle before bringing it home.


Giving all of your interior and exterior walls a lick of paint can make your property look fresh, clean and well presented without having to spend huge amounts of money. When choosing a paint colour to make your property more visually appealing, ensure you choose neutral tones that will be appreciated by the masses.
Adding plants, shrubs and flowers to your garden will give your property 'curb appeal' whilst making your property look inviting. Plants are also a cost effective way of making any outdoor space feel well-maintained and greenery can also provide much needed shade or a sense of privacy. When choosing which plants to add to your property, opt for something native that is well suited to the climate and doesn't require too much care and attention.
When it comes to selling houses, first impressions really do count and having a sparkling home inside and out is so important. There is no denying that a clean and hygienic home feels inviting and is more likely to sell. This means giving your house a regular deep clean making sure not to miss any of those nook and crannies. This is especially important if you own household pets or live with smokers.
Worn carpets, rugs or flooring can really put buyers off. Knowing that they may have to spend money replacing flooring shortly after moving in could stop a potential buyer from making that all important offer. Ideally, you would want to replace any areas of flooring or carpet that may be worn or damaged, but sometimes this is impossible due to a limited budget. If this is the case, opt for a professional clean to improve the overall appearance. If flooring or carpet is particularly worn or stained, then strategic placement of rugs could hide a multitude of sins.
There is nothing worse than a room that is untidy and full of clutter. Not only does clutter look messy, but it can make a room look considerably smaller. Tackle one room at a time and make sure to thoroughly organise your belongings. When everything has a place, it gives the illusion of a larger, more open space. Larger rooms are more desirable and thus, give your home more value.
If there are a number a small maintenance issues throughout your property, this will give the impression that the house has been neglected and therefore will seem less desirable. Even if you are not planning on putting your house on the market in the near future, keeping up to date with home repairs and maintenance can make the whole process easier when you decide to do so. When potential buyers see that the house has been well looked after and they will not be required to spend money on minor repairs or maintenance in the near future, this could mean they are willing to put in a higher offer.
Hiring professional help is a simple and easy way of getting a non-biased opinion on how your property could be improved. There are many property styling services in Melbourne that use the knowledge of trained experts to make sure the interior and exterior of your home look flawless to any potential buyers. Having a trained eye look at your property is one of the best ways of identifying small improvements that could make a huge difference when it comes to selling your home.
By following one or two of these easy to follow tips, you could ensure you achieve the asking price for your property, if not more! When putting your house on the market, even the smallest reno job can make a huge difference to the overall look and feel of the property and thus increase it's value!


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The Branco River is a tributary of the Aripuanã River in Mato Grosso in western Brazil. It merges into the Aripuanã River downstream from the town of Aripuanã

See also
List of rivers of Mato Grosso

References
Brazilian Ministry of Transport

Rivers of Mato Grosso

redpajama_set_name: RedPajamaWikipedia


A Baja Bug is an original Volkswagen Beetle modified to operate off-road, usually open desert, sand dunes and beaches. They originated in Southern California during the decade of free love where anything goes, the music was experimental and the cars often personalised. The Baja revolution in the late 1960s as an inexpensive answer to the successful Volkswagen-based dune buggies of the mid-1960s. Basic modifications were simple, the rear treatment leaves the engine exposed to aid cooling and a tubular steel cage (front and rear bumper) is fitted to the body and floor pan for protection of engine and occupants. The rugged torsion bar front and rear suspension standard on the Beetle, allows it to withstand the rigors of offroading and the rear ride height was easily raised slightly and stiffened to make clearance for larger heavy-duty off-road tires and wheels. The suspension was often extended to allow greater ground clearance and a more comfortable ride. But mostly, they were cool.
This standard 1303cc example was once the property of the vendor's mother and so it was a convenient jumping off point from which to begin a most thorough restoration lasting over two years. Separated into its individual constituent parts, it was then rebuild into traditional California-style Baja Beetle by DC Customs of Northamptonshire. With bills exceed an incredible £46,000 spent during that time; it is little surprise that it represents a truly sensational-looking example, reportedly also driving as good as it looks. Complete with a history file, Vodafone Tracker and MoT test certificate, this classic Baja Beetle is offered, incredibly, at no reserve.
Interested parties should note that this registration number is to be retained and a new age-related number issued instead.


Delivering world class expertise at Barnet, Chase Farm and the Royal Free hospitals. Bringing you the best of the NHS. Tweets monitored Mon-Fri 9am-5pm.
Thanks for drawing this to our attention. This was the result of an error on the part of the service provider which we understand will be rectified asap when the machine will be free to use.
A HUGE thank you to all our #NHSheroes working over #BankHolidayWeekend and to our #GPs and pharmacy teams working hard this week getting medications ready to be picked up before they close. Don't forget to pick up any prescriptions before the bank holiday!
Hi @notwaving, the shuttle bus is in place to help people get to the new Chase Farm Hospital, as its new location is slightly further away from the bus stop. Thank you.


Cancer rates among 1st responders and cleanup workers at Ground Zero have grown dramatically in the 15 yrs following the 9/11 attacks that destroyed the Twin Towers of the World Trade Center.
Almost 3,000 people were killed and 7,000 injured when Islamic Terrorists few commercial jetliners into the towers on September 11, 2001, releasing a toxic cloud of dust as the Towers collapsed.
According to the CDS, 5,441 people have cancers thought to be tied to 9/11. Most are between 55 and 64 years old, and most are emergency responders or recovery and cleanup workers.
Almost 70 types of cancer have been associated with the 9/11 attacks, many so aggressive they are hard to treat.
"The diseases stemming from the World Trade Center attacks include almost all lung diseases, almost all cancers — such as issues of the upper airways, gastroesophageal acid reflux disease, post-traumatic stress, anxiety, panic and adjustment disorders," Dr. David Prezant, co-director for the Fire Department of the City of New York's World Trade Center Medical Monitoring Program, said Saturday.


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Q: Calculating proportion to find sample size I have population, and I need to find a sample size using the equation
MoE = 1.96*/sqrt(p(1-p)/n * (N-n)/(N-1))

I know all values except n (obviously) and p...I am supposedly able to get a value of p from this information

Calculate the required sample size that would need to be distributed among survey interviewers if you do not want to allow more than 3% margin of error for all percentages calculated from the sample

Any ideas of how to find the value of p?

A: I believe you misunderstood the question. When it asks: "Calculate the required sample size" this means that the value of interest is $n$ and not $p$. The trick here is that you need to find a single value of $n$ that works for all possible values of $p$.
Since we are interest in finding $n$ we should isolate it in the expression for $MoE$:
$$n = N\left(1 + \frac{MoE^2(N-1)}{1.96^2p(1-p)}\right)^{-1}$$
I strongly encourage you to derive yourself the previous expression. Maybe I did something wrong :)
If we knew $p$ than all we have to do is compute the value given by the previous expression and select the first integer grater than the resulting value. But since we do not know $p$ we need to find a value of $n$ that works for all $p$.
Note that we can write $n = N*f(p)$ where $f(p) = \left(1 + \frac{MoE^2(N-1)}{1.96^2p(1-p)}\right)^{-1}$ and now it is clear that the correct value of $n$ is
$$n = N*\underset{0\leq p \leq 1}{\max}f(p)$$
But now we need to find $\underset{0\leq p \leq 1}{\max}f(p)$. First we note that $p(1-p)$ has a maximum in $p = 1/2$, consequently $1 + \frac{MoE^2(N-1)}{1.96^2p(1-p)}$ has a minimum at $p = 1/2$ and finally $\left(1 + \frac{MoE^2(N-1)}{1.96^2p(1-p)}\right)^{-1}$ has a maximum at $p = 1/2$.
After all of this we get that the value of $n$ that works for all $p$ is
$$n = N*f(1/2) = N\left(1 + \frac{4MoE^2(N-1)}{1.96^2}\right)^{-1}$$

redpajama_set_name: RedPajamaStackExchange


For your safety, ALL of the mandatory gear in the below link: 'Mandatory Gear List UTA22', must be carried by each runner at ALL times whilst in the event. The weather in the Blue Mountains can change quickly from extremely hot to very cold and wet and even to below zero and snowing. Whilst the course is 'only' 21.6km, it does descend into the remote Kedumba and Jamison Valleys where vehicle and emergency access can take extended periods of time. Be prepared for extreme conditions.
There may be random gear checks during the event and if you are missing any item you will receive a time penalty.
You are not required to get your mandatory gear checked prior to the UTA22. However, if you are uncertain about whether your gear meets the requirements then you should get your gear checked at one of the early gear check stores anytime between 13th January and 15th May.
If it is not possible for you to get to an early gear check shop and you are still uncertain about your mandatory gear, on the Thursday you can bring the gear in question to the 100km gear check area of Race Check-In at the KCC Auditorium. Make sure to tell the staff that you are in the UTA22 and not UTA100.


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Need a little pick-me-up or like your coffee to-go? No problem; there are many locally owned coffee shops and bakeries near our San Francisco hotel. We've also included a few restaurants to get something sweet for dessert or just a cool San Francisco treat.
Bean Bag Café: Since 1992, this café has been popular with locals for its organic and fair trade coffee, outdoor seating, brunch, and happy hour from 3 – 10 p.m.! It's only a four-minute walk to their location at 601 Divisadero Street. 415-563-3634.
Ben & Jerry's: Stop in for a cool treat at Ben & Jerry's ice cream shop in Haight Ashbury. Get a favorite flavor by the scoop, or in a sundae, or whipped up in a smoothie or shake. Just about a 15-minute walk to 1480 Haight Street. 415-626-4143.
Chile Pies: Find the perfect slice of sweet or savory freshly baked pie at this little shop, part of the Green Chile Kitchen family. They also have ice cream, ice cream cookie sandwiches, and ice cream pies available at 601 Baker Street. Open daily from noon to 10 p.m. and just a 10-minute walk. 415-614-9411.
KK Café: This friendly neighborhood café open for breakfast, lunch, and dinner. A two-minute walk from The Metro Hotel located at 252 Divisadero Street. 415-626-6188.
The Mill: Get a fresh, hot cup of coffee or artisanal bread at The Mill. They also host a special Monday pizza night and Wednesday grilled cheese and soup night. The Mill is located at 736 Divisadero Street, about six minutes from us, and right near Alamo Square and the Painted Ladies. 415-345-1953.
Three Twins Ice Cream: You'll find classic flavors with a quirky twist at 254 Fillmore Street, just nine minutes away. 415-487-TWIN.
Vinyl: Coffee bar by day wine bar by night with a low-key menu. Located just a couple of doors down at 359 Divisadero Street. 415-621-4132.


RD Casting is pleased to announce that the talented Jordan Sim will be appearing in the Northeast Producers christmas pantomime, Alice in Wonderland.
Well done Jordan for getting this awesome opportunity. Now go and show the world what you can do on that stage!


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es un pueblo localizado en la prefectura de Shimane, Japón. En junio de 2019 tenía una población estimada de 4.435 habitantes y una densidad de población de 15,7 personas por km². Su área total es de 282,92 km².

Geografía

Localidades circundantes
 Prefectura de Shimane
 Ōda
 Iinan
 Kawamoto
 Ōnan
 Prefectura de Hiroshima
 Miyoshi

Demografía
Según los datos del censo japonés, esta es la población de Misato en los últimos años.

Referencias

Localidades de Shimane


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Here's What Hedge Funds Think About M.D.C. Holdings, Inc. (MDC)
Published on July 5, 2019 at 4:01 pm by Nina Todic in Hedge Funds,News
Like everyone else, elite investors make mistakes. Some of their top consensus picks, such as Amazon, Facebook and Alibaba, have not done well in Q4 due to various reasons. Nevertheless, the data show elite investors' consensus picks have done well on average over the long-term. The top 20 stocks among hedge funds beat the S&P 500 Index ETF by more than 6 percentage points so far this year. Because their consensus picks have done well, we pay attention to what elite funds think before doing extensive research on a stock. In this article, we take a closer look at M.D.C. Holdings, Inc. (NYSE:MDC) from the perspective of those elite funds.
Is M.D.C. Holdings, Inc. (NYSE:MDC) a good investment today? Money managers are getting more optimistic. The number of long hedge fund positions improved by 1 in recent months. Our calculations also showed that mdc isn't among the 30 most popular stocks among hedge funds. MDC was in 17 hedge funds' portfolios at the end of the first quarter of 2019. There were 16 hedge funds in our database with MDC holdings at the end of the previous quarter.
Steve Leonard of Pacifica Capital
Let's analyze the latest hedge fund action surrounding M.D.C. Holdings, Inc. (NYSE:MDC).
How are hedge funds trading M.D.C. Holdings, Inc. (NYSE:MDC)?
Heading into the second quarter of 2019, a total of 17 of the hedge funds tracked by Insider Monkey held long positions in this stock, a change of 6% from the fourth quarter of 2018. By comparison, 16 hedge funds held shares or bullish call options in MDC a year ago. So, let's examine which hedge funds were among the top holders of the stock and which hedge funds were making big moves.
The largest stake in M.D.C. Holdings, Inc. (NYSE:MDC) was held by Polar Capital, which reported holding $19.2 million worth of stock at the end of March. It was followed by Royce & Associates with a $14.8 million position. Other investors bullish on the company included Millennium Management, Balyasny Asset Management, and Pacifica Capital Investments.
Consequently, specific money managers have jumped into M.D.C. Holdings, Inc. (NYSE:MDC) headfirst. GLG Partners, managed by Noam Gottesman, initiated the biggest position in M.D.C. Holdings, Inc. (NYSE:MDC). GLG Partners had $4.7 million invested in the company at the end of the quarter. Peter Rathjens, Bruce Clarke and John Campbell's Arrowstreet Capital also made a $2.5 million investment in the stock during the quarter. The other funds with brand new MDC positions are Matthew Hulsizer's PEAK6 Capital Management and Andrew Feldstein and Stephen Siderow's Blue Mountain Capital.
Let's now review hedge fund activity in other stocks – not necessarily in the same industry as M.D.C. Holdings, Inc. (NYSE:MDC) but similarly valued. We will take a look at JELD-WEN Holding, Inc. (NYSE:JELD), Solaredge Technologies Inc (NASDAQ:SEDG), Crescent Point Energy Corp (NYSE:CPG), and MaxLinear, Inc. (NYSE:MXL). All of these stocks' market caps resemble MDC's market cap.
JELD 21 327610 5
SEDG 22 115277 8
CPG 17 72343 1
MXL 6 33874 1
As you can see these stocks had an average of 16.5 hedge funds with bullish positions and the average amount invested in these stocks was $137 million. That figure was $103 million in MDC's case. Solaredge Technologies Inc (NASDAQ:SEDG) is the most popular stock in this table. On the other hand MaxLinear, Inc. (NYSE:MXL) is the least popular one with only 6 bullish hedge fund positions. M.D.C. Holdings, Inc. (NYSE:MDC) is not the most popular stock in this group but hedge fund interest is still above average. Our calculations showed that top 20 most popular stocks among hedge funds returned 6.2% in Q2 through June 19th and outperformed the S&P 500 ETF (SPY) by nearly 3 percentage points. Hedge funds were also right about betting on MDC as the stock returned 14.6% during the same period and outperformed the market by an even larger margin. Hedge funds were rewarded for their relative bullishness.
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World Radio Day Friday 13 February 2015
The 4th UNESCO World Radio Day is Friday 13 February. This year it focuses on radio for, by and with youth (i.e. people under 30 years old).
There are various events around the world and hopefully the day will engage with radio stations large and small too. I never understand why UK commercial stations and most BBC stations seem to ignore it. Considering the amount of air time they have to fill and judging by the mediocre content that many produce, you would think a chance like this would be a golden opportunity: Interviewing young people, hooking up with other stations, playing music from around the world suggested by young people and other stations, giving a show or two across to people under 30 to produce and present- the potential is great.
PCJ Radio International's Media Network Plus show of 31 January was ahead of the pack as usual. It interviewed UNESCO Chief of Section, Communication and Information Sector, Mirta Lourenco. She emphasised a need for greater social inclusion of the young generation. A speech from and BBC World Service Director Peter Horrocks stated his commitment to youth radio but I can see and hear nothing to back this up in actual content- it sounded like he was reading a script and giving empty platitudes but I look forward to being corrected.
Broadcasters from around the world will be on air live from UNESCO HQ in Paris on Friday, 13 February. These include MC Doualiya (ar) | Radio Orient (fr) | Radio VL (fr) | RFI (fr) | and Vivre FM (fr). The International Telecommunication Union (ITU), European Broadcasting Union (EBU) and UNESCO are also hosting a joint live broadcast all day, which will be streamed online. Visit the ITU website for more details.
There are also other events going on all over the world - see what's happening near you by visiting the World Radio Day Crowdmap. I am attending an event in London. Radio Romania International as always, will be hoisting a special programme for its shortwave and online audiences.
Check out the World Radio Day Soundcloud page too, now, on the 13th and after.
Happy World Radio Day for the 13th February, fellow listeners!
- February 07, 2015 No comments:
A plea to UK commercial and community radio stations
My message to CAT Radio in Cheshire on their launch.
Good luck with the launch of CAT Radio- Hope you follow the example of quality community stations such as Salford City Radio, ALL FM Manchester and Resonance FM in London, and produce diverse, informative, interesting programmes. Please don't be tempted down the route of most commercial radio stations and many community radio stations and end up relying on playing jaded old singles from the past. You have a chance to open your audiences' (and sponsors') ears to exciting new (and old) music and intelligent speech programming.
These opinions are my personal views and not necessarily those of any publishers, music organisations or clubs that I work with.
- February 03, 2015 3 comments:
A plea to UK commercial and community radio statio...


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Halle Berry Says She's Heartbroken No Other Black Woman Has Won Academy Award For Best Actress
February 3, 2022 by Kay Johnson in Film with 0 Comments
Bruised actress and director Halle Berry is opening up about some of the high moments about her stellar career as a multi-award winning actress. She also addressed the fact that 20 years after her historic Oscar win, she remains the only black woman to take home the award for best actress.
Halle Berry has previously been open and honest when discussing the surprise she felt post her historic Oscar win. In an earlier interview she stated:
"It was surprising. Because I thought they were going to just back up the truck and drop [the job offers] off at my house, right? When you have a historic win like that, you think, 'Oh, this is going to fundamentally change.' It did fundamentally change me, but it didn't change my place in the business overnight. I still had to go back to work. I still had to try to fight to make a way out of no way."
In a recent promotional of ABC's Soul of a Nation, a special centering around the history and rise of notable Black actresses, the 55-year old actress touches on the topic of still being the only Black woman to win the award 20 years later.
After being asked if her hopes for the success of future Black actresses has come to fruition, which she mentions during her iconic 2002 acceptance speech, Halle Berry had this to say:
"I've been asked this question so many times as if I should have the answer, but I don't. But I will say this, I do feel completely heartbroken that there's no other woman standing next to me in 20 years"
She continued:
"I thought, like everybody else, that night meant a lot of things would change. That there would be other women. I thought I would have the script truck back up to my front door and I'd have an opportunity to play any role I wanted. That didn't happen. No other woman is standing there."
Though there has yet to be a breakthrough of other Black women winning the award, the actress says she does believe the win inspired more Black creatives to dream big.
"When I look around and I see my brothers and sisters working and thriving and telling their own stories from their point of view, I'm proud of that. And I see the movement forward. And I think that night inspired so many of those people to dream those dreams."
The Academy has been under fire many times for their lack of representation in film and media, and most recently received backlash after releasing an appreciation tweet towards Hattie McDaniel, the first African American to win an Oscar.
Do you think we'll see another Black woman win the award anytime soon? Tell us what you think in the comments!
Tags: academy awards, halle berry, recommend
Authored by: Kay Johnson
Michael B. Jordan Tells Chadwick Boseman "I Wish We Had More Time" & Reflects On One Of Their Final Conversations
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DC Young Fly Says Chris Tucker Told Him If He Plays His Son He'll Do Another 'Friday' Movie
John Boyega Is Worried His Previous Black Lives Matter Speech Could Hurt His Career
'Black Panther's Winston Duke Reveals His Mother Recently Passed Away + Opens Up About Filming Sequel Without Chadwick Boseman: In Death, The Struggle Is Finding Ways To Hold Onto People
Halle Berry Tells Fan Who Says She 'Can't Keep A Man': Who Says I Wanna Keep The Wrong One?
Actor LaKeith Stanfield Calls Charlamagne A 'H*e' After He Shades 'Judas & Black Messiah' Role


This authentic Fendi By The Way Satchel Calfskin Small presented in the brand's 2014 Collection showcases a modern, understated style admired by every fashionista. Constructed from taupe leather, this minimalist and functional duffle features dual flat leather top handles, stamped Fendi foil logo, metal Fendi tag with off-white leather tag, and silver-tone hardware accents. Its top zip closure opens to a grey fabric-lined interior with a middle zip compartment and slip pockets perfect for storing bare essentials. The bag's detachable strap allows it to be worn longer on the body for added versatility. A beautiful, stylish piece only from Fendi. Authenticity code reads: 8BL124-W7Q 149-2516. **Note: Shoe photographed is used as a sizing reference, and does not come with the bag. These are professional pictures of the actual bag offered by Rebag.
Condition: Great. Minimal wear on base corners, slight creasing on exterior, minor scratches on hardware.
Accessories: Dust bag, detachable strap, leather clochette, decorative keychain, care card.
Measurements: Handle Drop 2", Height 6", Width 11", Depth 5.0", Strap Drop 13"


The City of Munich and the Free State of Bavaria are currently deciding on the design and location of a new memorial remembering the victims of the 1972 Olympia terrorist attack during which 11 Israeli athletes and one Bavarian policeman were killed. The location where the memorial should be erected has long been argued about, and there have also been opinions that there shouldn't be a memorial at all.
Now it seems that the host of different experts involved have come to a decision on the location and the design. The memorial will be located in the midst of the Olympiapark, on the so called Lindenhügel hill. Other discussed locations were the Studenten and the Conolly hills of the park. The Studenten was dismissed because students and inhabitants nearby felt that the memorial would be too close to their homes, the Conolly hill is a popular sleigh ride site during wintertime.
Bavaria's Minister of Culture Ludwig Spaene (CSU) finds the location suitable because it is set in the middle of the Olympiapark, which combined with the elevated position, makes it easy to spot from almost anywhere within the park. He pointed out that: "We want to return dignity to the victims." The memorial will cost 1.75 million Euros and will be financed by the Free State of Bavaria, the City of Munich, Federal government, as well as the International and the German Olympic Committee.
The families of the victims of the 1972 attack will be involved in the process of gathering documents and other exhibits at the memorial. The Israeli Consul praised the design of the memorial by the Brückner & Brückner architect firm.


Online Reviews: 7 Rules of Engagement for Restaurants. How to use online reviews and your response to them to drive business and guest loyalty.
When was the last time you read through your Facebook reviews? Or (please don't quit reading already) hopped over to your business page on Yelp? Taking a few minutes to address your guests' feedback on review sites is literally the last thing on the priority list of "things to do" for most businesses, but I will maintain that it's essential.
2. Competition in industries across the board has grown exponentially.
These two realities are changing a business' relationship with its customers.
With an influx of information at their fingertips, people have become more adept at tuning out what's not relevant to what they're looking for. We simply can't push our agenda on customers anymore like we used to, so now we have to adjust to figure out how to attract them to what we have to say. In a world where businesses are realizing more and more that they are competing for attention rather than action (sales, clicks, inquiries, etc.), strategies are beginning to shift. This is why you keep hearing about this thing called "content marketing" and even though it's been around forever, it's more important than ever to have a plan for it.
You could argue that literally anything you put out as a business could fall into this category, and you'd be right. But, the key here is in how we define "valuable, relevant and consistent". In this case, content has to be all those adjectives at once… from the point of view of your customer.
This sounds pretty basic, but it's a total shift in mindset for a business because good content that will attract a potential customer and stand out from the competition has to be devoid of any direct benefit to the brand itself. Good content does not explicitly sell your product or solution, and it also doesn't promote a discount or offer.
In fact, good content doesn't mention your product or service at all.
Publishing good content and distributing it to a targeted audience establishes authority (you're the one giving them the answers!) and keeps your brand top of mind. It's helpful in the sense that the information you're providing shows why a customer may want to make a purchase sometime in the future.
If you can solve a problem or provide more information to a customer at the time he or she seeks it, you've introduced your brand to them long before they've made a conscious decision that they need to buy something in the first place. The goal is that once they are ready to make that decision, you're the solution that first comes to mind.
The list goes on… Choose one thing to start with and gauge your response over time.
The most important thing is that your content is valuable.
For it to be valuable, you've got to know exactly who you're speaking to and do some work on what your customers' biggest hurdles are. What kind of questions [relevant to your business and the solutions you offer] might they have? This is your chance to answer them so they're more informed about what they're looking for. Once you start doing this consistently, you become the natural choice when they want to take the next step.


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Home Blog 8 People, Including Las Vegas Man, Indicted on Campaign Finance Charges
8 People, Including Las Vegas Man, Indicted on Campaign Finance Charges
Roy Boulos, age 52, of Las Vegas is one of eight individuals being named in an unsealed indictment, charged by the Justice Department for conspiring to make and conceal excessive campaign contributions during the 2016 presidential election. The contributors schemed to gain influence with political leaders of both parties. Experienced Las Vegas criminal defense attorneys say that contribution schemes like this are common during more publicized election cycles.
Why Is This Case of Importance?
This particular case has gained national attention due to the fact that one of those being indicted, George Nadar, was a major donor to Hillary Clinton's campaign and is also a witness in the ongoing Robert Mueller investigation regarding Russian meddling in the 2016 elections.
Another nearby individual indicted is Ahmad Khawaja of Los Angeles, who was allegedly conspiring alongside Nader to conceal the source of $3.5 million in campaign donations.
How Is the Las Vegas Man Connected to the Contributions in Question?
As for Roy Boulos, he owns "Roy's Wine and Cigars" in Summerlin and is being accused of conspiring with Khawaja and others to make contributions through conduits to conceal excessive contributions. Roy and his wife have declined comments and referred reporters to their attorney, David Chesnoff. Chesnoff is a nationally known criminal defense lawyer; he also did not return requests for comments.
Boulos was an active donor to various political candidates, parties, and committees, according to Federal Election Commission records. In addition to local donations, Boulos gave over $300,000 to the Hillary Victory Fund. After the 2016 election, he gave over $135,000 to the Republican National Committee (he was a registered Republican.)
The indictment charges the group of 8 individuals with concealing $1.8 million in excessive campaign contributions between 2016 and 2018 as well as lying to the FBI and obstructing a grand jury investigation.
Donors Sought Privilege Through Donations
The donations were meant to help the individuals gain access and privilege to the winning candidate. For example, Khawaja received an Oval Office reception with Trump after his inauguration. Nadar was a frequent White House guest and had ties to the UAE's crown prince.
As for Boulos, his privilege is unreported at this time. However, it would do him some good to distance himself from the rest of the members of this group. Especially considering Nadar is currently in federal custody on child pornography charges.
By Half Price Lawyers on Monday, December 23, 2019
This entry was posted in Criminal Defense. Bookmark the permalink.
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Georgia officer who shot fleeing black man charged with voluntary manslaughter
"The senseless killings of black men by police must stop," the family of Anthony Marcel Green, who was killed during a traffic stop, said in a statement.
June 28, 2018, 11:24 AM UTC / Updated June 28, 2018, 11:24 AM UTC / Source: Associated Press
KINGSLAND, Ga. — A Georgia police officer was in jail on Thursday, charged with voluntary manslaughter and violating his oath of office, after state investigators said he fatally shot a black man who was running away from him last week.
Kingsland Police Officer Zechariah Presley surrendered Wednesday to the Camden County Sheriff's Office after the Georgia Bureau of Investigation obtained warrants for his arrest.
Kingsland Police Officer Zechariah Presley.Kingsland Police Department / AP
A GBI statement says Presley, who is white, was following a vehicle that stopped at an intersection on June 21 when the driver and passenger ran. Presley pursued the driver, later identified as Anthony Marcel Green.
Presley, 25, caught up with Green, 33, making physical contact, but Green again fled, "at which time Presley fired multiple shots resulting in the death of Green," the statement says.
Green's family attorney, Reginald Greene, released a statement saying the family is "seeking justice."
"Tony Green was gunned down in cold blood by Officer Presley. We are encouraged by his swift arrest, but we intend to remain vigilant until he is brought to justice and the family is able to get answers as to why this happened in the first place. The senseless killings of black men by police must stop," the statement said.
Pastor Knight, friend of the Green family, says they are relieved and hopeful to hear Officer Presley turned himself in, he told me they're one step closer to justice. @FCN2go pic.twitter.com/NHlaoIXos8
— Janny Rodriguez (@JannyReports) June 27, 2018
Local media reported that Kingsland Police Chief Daryl G. Griffis recommended terminating Presley, and Kingsland City Manager Lee Spell agreed.
The department also released Presley's personnel file, which shows he was hired last year despite admitting that he had physically fought with his wife, had bought or sold marijuana, repeatedly shouted at people, was involved in "2-3" accidents and had been arrested for "reckless, eluding, speeding," according to his handwritten text.
Presley also racked up nine incidents during in his year in the police department, at one point parking outside the house of a black man who had complained to the chief, prompting the man to say that Presley had him fearing for his life.
Green's record, the station says, includes a traffic ticket in March for a suspended license and a 2016 misdemeanor arrest.
Presley is being held in the Glynn County Jail rather than the Camden County Jail, where he worked as a guard before joining the police force. Local media reported that they couldn't determine whether he has an attorney who might speak on his behalf.


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Birmingham International Airport
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Some of the world's leading wineries place unconditional trust in cork stoppers as the best closure system for wines and Champagnes.
They are the best partners for preserving cork closures.
Interview with Bernard Nobled of Romanée Conti.


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Jamshedpur Reporter
Schneider Electric Partners with the Global Manufacturing and Industrialisation Summit to Promote the Role of Sustainability and Digital Transformation in the Global Manufacturing Sector
Schneider Electric is partnering with the Global Manufacturing and Industrialisation Summit (GMIS) to focus on the roles that digital transformation and green technologies will play in transforming the manufacturing sector in the United Arab Emirates and globally.
Through the exchange of knowledge and shared programs, Schneider Electric will engage with the Global Manufacturing and Industrialisation Summit to help manufacturers best understand how they can leverage digital transformation and green technologies to become more efficient, productive and sustainable. A number of the company's executives will lead talks on how manufacturers can optimise their operations to create "Factories of the Future". Schneider Electric will also join the Green Chain initiative, to develop a roadmap to advance the decarbonisation of industry by developing new renewable energy global value chains.
Scheduled to be held at EXPO's Dubai Exhibition Center from November 22-23, the fourth edition of the Summit (#GMIS2021) offers a unique international platform to share lessons and explore opportunities, as leaders from the global manufacturing and technology communities engage in discussions and debates that are shaping the future of manufacturing and industrialisation.
"Decarbonizing the global economy is about moving away from burning fossil fuels and stepping up electrification and clean energy alternatives. But it's also about being smarter and more efficient with our resources and energy usage. Here is where Digital technologies can help us making decisions smarter, faster, more precisely – all of which is ultimately better for the planet " said Luc Remont, Executive Vice-President, International Operations of Schneider Electric. "If we want to achieve this, we need to think big, scale fast and take regular, small but decisive actions for a greener industrial future and a greener planet. Moreover I want to remind you all – optimising energy use while systematically improving process and resource efficiency will transform operations and deliver low carbon emissions. This means more resilience at a lower costs. So, what manufacturer doesn't want this?"
One of the largest manufacturers in the energy and automation space, Schneider Electric developed its first sustainability strategy several decades ago. Today, seventy percent of the company's revenues are green, from products that reduce resource consumption. Schneider Electric's sustainability goals include delivering 800 million tons of saved and avoided CO2 emissions to customers by 2025. Schneider Electric's sustainability consulting expertise is based on the company's own journey to become more efficient and less resource intensive; in September of this year the company's Smart Factory in Lexington, Kentucky was recognised as a Sustainability Lighthouse – one of only three worldwide – by the World Economic Forum (WEF). Schneider Electric's technology led to a 26% energy reduction (GWh), 30% net CO2 reduction, and 20% water use reduction at the facility.
Badr Al-Olama, Head of the GMIS Organising Committee, said: "Sustainability and climate action are central to our mission at GMIS and we are committed to partnering with organisations that recognise the importance of making a positive impact on the environment. For years, Schneider Electric has consistently delivered on their promise to improve our planet while developing disruptive digital solutions across sectors, including infrastructure and data centres. We are proud to partner with Schneider Electric to promote widespread growth and innovation in the industrial world while shaping an environmentally sustainable future for all."
#GMIS2021 is a joint initiative of the United Nations Industrial Development Organization (UNIDO) and the United Arab Emirates Ministry of Industry and Advanced Technology. With the event coinciding with Dubai Expo, the Summit will position industrialisation at the center of the global dialogue, reinforcing the sector's important role in driving economic growth and global prosperity. Under the theme 'Rewiring Societies: Repurposing Digitalisation for Prosperity', #GMIS2021 will explore the importance of data intelligence and connectivity, and the evolving mechanisms of interaction between humans and machines in the context of the Fourth Industrial Revolution.
#GMIS2021 will be held during the six-day GMIS Week from November 22-27, featuring over 200 global speakers. The GMIS Week will include a Global Prosperity Conference and an Alternative & Renewable Energy Conference – The Green Chain Conference – on November 24 and country focused conferences in partnership with the United Kingdom, Australia and Italy. The event will also run a six-day manufacturing and advanced technology exhibition to showcase some of the UAE's most innovative capabilities.
About Schneider Electric
At Schneider, we believe access to energy and digital is a basic human right. We empower all to do more with less, ensuring Life Is On everywhere, for everyone, at every moment.
We provide energy and automation digital solutions for efficiency and sustainability. We combine world-leading energy technologies, real-time automation, software and services into integrated solutions for Homes, Buildings, Data Centers, Infrastructure and Industries.
We are committed to unleash the infinite possibilities of an open, global, innovative community that is passionate with our Meaningful Purpose, Inclusive and Empowered values.
Company Name: ABC Private Limited
Website: https://www.se.com/in/en/
Respiratory Care Devices Market worth $27.6 billion by 2026 – Key Players are Philips Healthcare (Netherlands), ResMed Inc. (US)
Enteral Feeding Devices Market worth $4.9 billion by 2026 – Key Players are Cardinal Health Inc. (US), Cook Medical (US), Moog Inc. (US), Fresenius Kabi (Germany)
© 2020 Copyright Jamshedpur Reporter. All Rights reserved.


US vice president Joe Biden on Thursday hailed the premier Indian Institute of Technology, Bombay as "one of the leading" technology schools in the world that left him "extremely impressed".
"I have been extremely impressed. This is a great university, one of the leading universities in the world in the field of technology," he said after visiting various laboratories and interacting with students on the campus.
Biden's comments came amid talk of declining standards of education in the country.
After visiting the departments of Nano Technology and Earth Sciences, he held a closed-door meeting with female students pursuing doctoral studies in multiple disciplines.
"We are looking at India's future. I mean it," he said, citing the oft-used quote "women are half the sky".
Biden, who wrapped up his four day India visit with IIT-B as his last port of call, particularly appreciated the diverse work being done by the female students he met in areas as varied as transportation, education and medicine.
Accompanying US officials said the meeting was part of an Indo-US partnership on 'women in science'.
"To see these women engaged in science, technology and engineering is something worth promoting very heavily in the US. In the US, now more women graduate from college than men and still there are only 20% or so entering the science stream," he said.
Biden, the first US vice president to visit India in the last three decades, said the future of the people of this country which is "most open and most representative" is much better.
"We have to take advantage of the collective capabilities of our population," he added.