text:
Richard Cole, last surviving member of the Doolittle Raiders, dies at 103 in Texas
Retired Lt. Col. Richard Cole, 103, was the last survivor of the first U.S. strike on the Japanese islands during World War II.
Richard Cole, last surviving member of the Doolittle Raiders, dies at 103 in Texas Retired Lt. Col. Richard Cole, 103, was the last survivor of the first U.S. strike on the Japanese islands during World War II. Check out this story on USATODAY.com: https://www.usatoday.com/story/news/nation/2019/04/09/richard-cole-doolittle-raiders-dies-103/3416542002/
N'dea Yancey-Bragg and Meg Jones, USA TODAY Published 7:03 p.m. ET April 9, 2019 | Updated 8:37 p.m. ET April 9, 2019
Retired Lt. Col. Richard Cole is 97, but that didn't stop him from taking the controls and flying a vintage B-25 bomber at a reunion of the famous World War II Doolittle Raiders. (April 18) AP
Retired Lt. Col. Richard Cole, the last survivor of the Doolittle Raid, the first U.S. strike on the Japanese islands during World War II, died Tuesday in Texas. He was 103.
Cole was one of 80 men sent to target factory areas and military installations in Japan on April 18, 1942. The daring raid stunned Japan and is credited with boosting U.S. morale and helping turn the tide of the war in the Pacific.
"There's another hole in our formation. Our last remaining Doolittle Raider has slipped the surly bonds of Earth, and has reunited with his fellow Raiders," General David Goldfein, chief of staff of the Air Force said Tuesday. "The Legacy of the Doolittle Raiders – his legacy – will live forever in the hearts and minds of Airmen, long after we've all departed."
Richard Cole was the last surviving member of the Doolittle Raiders (Photo: Meg Jones/Milwaukee Journal Sentinel)
Cole, born in Dayton, Ohio, was mission commander Jimmy Doolittle's co-pilot in the all-volunteer attack which took place less than five months after the Japanese attack on Pearl Harbor.
After bombing targets in northwest Tokyo, Cole's plane turned toward China with plans to land at an airfield. But things went awry when authorities at the airfield heard their engines, assumed it was Japanese and turned off the lights. Cole and Doolittle couldn't find a place to land at night.
Shortly before running out of fuel, everyone bailed out; Cole gave himself a black eye when he pulled his parachute ripcord. He landed in a tree where he spent the night, climbing down in the morning, and walking the whole day before finding a couple of Chinese students who eventually took him to Doolittle, who said, "Boy, am I glad to see you."
Richard Cole: Last Doolittle Raider remembers historic mission 75 years ago
David Thatcher: 79th Doolittle Raider dies in Montana
Of the 80 men who flew from the USS Hornet deck, three died in the raid, and four who were captured by the Japanese were executed or starved to death. Two others who survived the raid were later killed while flying the China-Burma-India route over the Himalayas known as the "Hump."
After the raid, Cole went to India, helped establish the dangerous Hump flying route and flew more than 100 missions carrying cargo, earning three Distinguished Flying Crosses.
The Doolittle Raiders received the Congressional Gold Medal in 2015, and donated it to the National Museum of the U.S. Air Force in Ohio.
Cole, who often attended Raider-related events and air shows, told The Associated Press last year that since he was older than many of the other Raiders, he didn't expect to be the last.
"I figured that Mother Nature and the good man upstairs would pick the time, and I wouldn't have any control over it," he said.
Cole will be buried at Arlington National Cemetery, the Air Force Times reported, and memorial services are also being scheduled at Joint Base San Antonio-Randolph in Texas.
Contributing: Jenn Rowell, Great Falls (Mont.) Tribune; The Associated Press
Follow N'dea Yancey-Bragg on Twitter: @NdeaYanceyBragg
The last of World War II's Doolittle Raiders has died at 103
One of Lt. Col. Jimmy Doolittle's B-25 bombers takes off from the flight deck of the USS Hornet for the initial air raid on Tokyo, April 18, 1942 . The raid came just four months after Japan attacked Pearl Harbor, the Doolittle raid did little damage, but lifted the spirits of Americans. AP
Former Lt. Col. Richard E. Cole was serving as the Grand Marshal of the Memorial Day parade in Washington D.C. on May 26, 2014. Cole was the co-pilot of Jjmmy Doolittle during the Doolittle Raid on Tokyo and was the last remaining Raider, he passed away April 8, 2019. Jack Gruber, USA TODAY
Lt. Gen. Jimmy Doolittle shows a photo of a B-25 bomber crew that bombed Tokyo with him on April 18, 1942. At the time he was preparing for 41st reunion with 37 other survivors of the famous World War II air raid. Doolittle led 15 bombers from the aircraft carrier "Hornet" in the first raid of Japan earning him the Congressional Medal of Honor. Clay Peterson, AP
Retired Air Force Lt. Col. Richard "Dick" Cole, a surviving member of the 1942 raid on Tokyo led by Lt. Col. Jimmy Doolittle, opens an 1896 bottle of cognac the Raiders had been saving for their final toast, at the National Museum of the U.S. Air Force at Wright-Patterson Air Force Base in Dayton, Ohio, Nov. 9, 2013. Cole, a co-pilot in the Doolittle Tokyo Raiders lead plane died April, 8, 2019. Al Behrman, AP
Generals George S. Patton Jr., left, and James H. Doolittle after their arrival in Los Angeles, June 9, 1945. AP
Doolittle Raider David J. Thatcher at the National Museum of the United States Air Force in Dayton, Ohio on the 70th anniversary of the Doolittle raid on Tokyo, April 18, 2012. Mark Duncan, AP
Former President George H. Bush assists James H. Doolittle during a White House ceremony where Doolittle was the recipient of the Presidential Medal of Freedom, July 6, 1989. Doolittle at the time was the aviation pioneer and retired military general who made history by leading the first U.S. air strike on Japan following the Japanese attack on Pearl Harbor. Rick Bowmer, AP
Lt. Gen. James H. Doolittle, commanding general of the U.S. Eighth Air Force, receives the Croix de Guerre medal from Lt. Gen. Pierre Koenig, commanding general of the French Forces of the Interior and Military Governor of Paris during ceremonies, Sept. 22, 1944. AP
Thirty members of Jimmy Doolittle's Tokyo Raiders pose for a group picture in front of a B-25J bomber in April 17, 1987 while gathering for a reunion in Los Angeles. Forty-five years ago on April 18, 1942, 80 U.S. Army Air Force airmen took off from the deck of the aircraft carrier USS Hornet in 16 B-25 bombers to bomb Tokyo. Douglas C. Pizac, AP
This is Maj. Gen. James Doolittle's bomber after it crashed on April 22, 1943 in China following the raid on Japan. AP
Major General James H. Doolittle straps himself into the cockpit of his plane, Jan. 28, 1943, before a flight over the Tunisia, North Africa, front. AP
Former President Barack Obama signs H.R. 1209 in the Oval Office of the White House, May 23, 2014. The act awarded a Congressional Gold Medal to the members of the Doolittle Tokyo Raiders in recognition of their military service during World War II. From back left are Sen. Sherrod Brown, D-Ohio, Lt. Col. Richard Cole, WWII Raider, United States Air Force (Retired), and Rep. Madeleine Bordallo, G-Guam. Jacquelyn Martin, AP
Dolittle Raider Edward J. Saylor in Dayton, Ohio commemorating the 70th anniversary of the Doolittle raid on Tokyo, April 18, 2012. Mark Duncan, AP
Silver cups with the names of the Doolittle Raiders sit in a case with a bottle of cognac at the National Museum of the United States Air Force in Dayton, Ohio April 18, 2012. At the time, the four surviving crew members toasted their comrades in a private ceremony for the 70th anniversary of the Doolittle raid on Tokyo. The upside down cups represented the deceased members at the time. Mark Duncan, AP
Surviving Doolittle Raider David J. Thatcher at the National Museum of the United States Air Force in Dayton, Ohio commemorating the 70th anniversary of the Doolittle raid on Tokyo, April 18, 2012. Mark Duncan, AP
Doolittle Raiders Lt. Col. Richard Cole, Staff Sgt. David Thatcher and Lt. Col. Edward Saylor answer questions about the Doolittle Tokyo Raid during a press conference April 17, 2013 at the Air Force Armament Museum on Eglin Air Force Base in Fla. AP
U.S. Army Air Corps navigator Hank Potter who was a Doolittle Raiders, arrives at the world premiere of "Pearl Harbor," which was shown on the deck of the Navy aircraft carrier USS John C. Stennis, May, 21, 2001. MIKE NELSON, AFP/Getty Images
Retired Air Force Maj. Gen. Davey Jones leads the "Doolittle Raiders" as they drink a toast to their fallen comrades during the Solemn Goblet Ceremony at their 60th reunion April 18, 2002 in Columbia, SC. Jones was one of 14 remaining Raiders to attend the reunion and honor his fallen comrades. The first Raider reunion was held in 1945 at the behest of their commander Lt. Col. Jimmy Doolittle who planned and led the raid to bomb five major cities in Japan in retaliation for Japans unprovoked attack on Pearl Harbor. USAF, Getty Images
A B-25 bomber trailed by another and a Japanese Zero makes it's landing approach over Wright Patterson Air Force base in Dayton, Ohio, April 17, 2012. Twenty of the World War II bombers flew in for the 70th anniversary of the Doolittle raid on Tokyo. Mark Duncan, AP
Read or Share this story: https://www.usatoday.com/story/news/nation/2019/04/09/richard-cole-doolittle-raiders-dies-103/3416542002/


If you're applying for a graduate position in Australia there's a good chance you will be faced with CEB's SHL Numerical Reasoning test as part of your potential employer's recruiting process. This article will help you learn about CEB's SHL Numerical Reasoning tests in Australia, what these tests are like and how to prepare for them.
Get hold of practice tests for SHL's Numerical tests here.
SHL is the most widely used assessment company in Australia and the world. Their online tests cover virtually all types of aptitude test for a variety of different positions. Recently SHL was purchased by the American firm CEB though their tests services remain unchanged.
Companies in Australia make use of their services when sifting through a large number of prospective job candidates.
One of the most widely used of these tests is the SHL Numerical Reasoning test.
What is the SHL Numerical Reasoning test?
SHL's Numerical Reasoning tests are made up of mathematical type questions that test your ability to analyse data and solve numerical problems. These questions often come with diagrams, graphs or tables and include questions dealing with proportions, percentages or ratios.
SHL's Numerical Reasoning test can come in a variety of different forms and difficulties depending on the position you're applying to.
Numerical Interpretation & Numerical Evaluation: These tests are designed for Sales and Customer service positions. These tests are labelled as either NCC2 or NCC4 with NCC4 being the more difficult of the two.
Interpreting Data: This test type is designed for positions involving decision making and analysis. The difficulty level of Interpreting data tests can run from basic to moderate levels. This test is labelled NC2.3.
Numerical Critical Reasoning: This group of tests are used on applicants applying for Graduate and Managerial positions. These tests can vary from moderate to advanced in their level of difficulty and can require the knowledge of Industry-relevant data. The tests can be referred to as NMG1-6 or as Management and Graduate Item Bank (MGIB).
Numerical Reasoning & Numerical Analysis: These are the hardest level of SHL Numerical tests. They are used candidates applying for Senior Manager and Information Technology positions. These tests usually include questions dealing with ratios percentages and probability. They are labelled as NMT2 and NMT4.
SHL's Verify tests make up an integral part of their assessment process. These are their online aptitude tests sent to candidates to complete at home before coming in for an interview or assessment centre. Shorter versions of these tests are often presented at assessment centres as well as verification that the online test was done by the candidate.
Like all of SHL's products, the Verify version of their Numerical tests come in different difficulty level depending on position. These tests usually give you between 15 to 25 minutes to answer about 10 to 20 questions.
A rumour about an upcoming recession in Japan will reduce the value of the Yen by 7% compared with the Euro. After the reduction, How many Euros would you be able to buy for 500 Yen?
You can get more information as well as comprehensive practice materials for SHL numerical tests here.
You can find out about other aptitude tests used by employers at JobTestPrep.
would you be so kind to explain in details about the numerical interpretation & numerical evaluation?
Why is it labelled as NCC2 and NCC4? I'm still pretty confused and my head is probably aching after reading such article. Do we have to take this test when we apply for a job in America ?
Are there anyways to prepare for this thing? I'm turning curious and maybe stupid lol.
We have checked with the test provider and NCC2 is easier than NCC4 test. To give our readers a better understanding of different kinds of numerical reasoning tests, we might write an article on this subject later. For the mean time, you can browse other articles we have on psychometric tests such as Hogan, Revelian tests in the "Most Popular Posts" menu on the top right corner. Cheers.


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Gender equality and inequality (-) (33)
Youth (-) (8)
Sexual harassment (-) (1)
Asia and the Pacific (15)
Latin America and the Caribbean (15)
OECD DAC Donors and Other Countries (15)
Profil Genre Tunisie 2022
The Swiss Embassy in Tunisia has provided financial support for the UN Women's programme "Contribute to the establishment of a system of collection and production of gender statistics in Tunisia" and within this framework that this study is contributing to the implementation of a system of collection and production of gender statistics in Tunisia in collaboration with strategic partners, mainly the National Council of Statistics.
Women-owned Businesses in the United Arab Emirates: A Golden Opportunity
Date: Monday, 22 August 2022
Women-owned businesses (WOBs) in the Middle East and Northern Africa (MENA) region could make significant contributions to entrepreneurial activity and countries' economic growth, but face challenges and barriers. This report examines access to finance in the United Arab Emirates for WOBs; describes government and private measures to promote women's entrepreneurship; looks at global best practices and makes recommendations for policymakers and stakeholders to improve women-owned businesses' access to financing.
Etat des lieux des inégalités et de la discrimination à l'encontre des femmes & des filles dans la législation tunisienne
Le Bureau du Haut-Commissariat des Nations Unies aux Droits de l'Homme en Tunisie, l'ONU Femmes Tunisie et le Centre de recherche, d'études, de Documentation et d'Information sur la Femme(CREDIF) ont conjointement réalisé une étude relative à l'état des lieux des inégalités et de la discrimination à l'encontre des femmes et des filles dans la législation tunisienne en en 2016 puis mise à jour en 2021.
Gender Equality, Women's Empowerment (GEWE) and HIV in Africa: The impact of intersecting issues and key continental priorities
Date: Sunday, 15 August 2021
This study and brief aim at providing insights on how gender and other intersecting inequalities impact the risk and vulnerability to HIV for women and girls in Africa.
Lebanon's Feminist Civil Society Platform calls for ensuring a fair and equitable space for women in the political sphere
The members of Lebanon's Feminist Civil Society Platform met on 22 September to express their concern about the drastic regression of women's representation in the recently formed government in Lebanon. Women's rights and opportunities to equal participation in decision-making should be institutionalized; therefore, the signatories to this statement issued a list of demands that must be met in order to truly encompass a fair and equitable space for women in the political sphere. The statement highlights the upcoming parliamentary and municipal elections and reiterates the demands made by the Platform since August 4, 2020.
Priorities for Gender Equality in Yemen's COVID-19 Response
The brief explores the impact of the coronavirus pandemic and its gender dimensions in conflict settings with a focus on gender-based violence (GBV), women's participation in decision-making, labour markets and livelihoods. The paper outlines gender issues and recommendations for stakeholders and national/international actors with the aim of providing effective mitigation measures and actions in response to COVID-19.
UN Women Lebanon newsletter January-March 2020
Date: Tuesday, 5 May 2020
This UN Women newsletter is a brief summary of news related to women's rights and gender equality in Lebanon during the reporting period. It also includes data and trends regarding the impact of the outbreak of the COVID-19 pandemic on women and girls in Lebanon, and on UN Women's work at both the individual, community and national level, to respond to the crisis.
Online and ICT-facilitated violence against women and girls during COVID-19
Date: Thursday, 30 April 2020
This brief highlights emerging trends and impacts of COVID-19 on online and ICT-facilitated violence against women and girls (VAWG). It provides examples of strategies put in place to prevent and respond to online/ICT-facilitated VAWG and makes recommendations on how different actors can best address this issue. It is a living document that draws upon the knowledge and experience of a wide range of experts.
Understanding the Role of Women and the Feminist Actors in Lebanon's 2019 Protests
Women have been at the core of Lebanon's popular protests since they began on October 17, 2019. Assessing the first 58 days of protests, this paper seeks to contribute to the documentation of women's representation, roles, and demands within Lebanon's protests, while also examining the use of gendered language and norms by all sides of thecountry's complex landscape. It situates this action within the broader women, peace and security framework, which recognizes women as political actors and peace and security leaders and brokers.
Beijing+25 Arab States Newsletter
Date: Sunday, 24 November 2019
In 1995, over 17,000 representatives from 189 nations met in Beijing at the Fourth World Conference on Women. The historic meeting resulted in the unanimous adoption of the Beijing Declaration and Platform for Action; an agenda considered to be the "Bill of Rights" for women. 25 years after Beijing, Member States, civil society organizations and women's rights advocates from across the globe are coming together to review the implementation of this agenda. Our newsletter will focus on the individuals and institutions leading this global process in the Arab States region.
Steps Taken in the Arab Region for the Implementation of the Beijing Declaration and Platform for Action
Date: Saturday, 23 November 2019
This brochure aims to provide a preliminary summary of the achievements of the Arab countries in implementing the Beijing Declaration and Platform for Action 25 years after its adoption, focusing on the intersections of the twelve areas of concern with the sustainable development agenda.
Addressing Gender Amongst Syrian Refugees in Lebanon
In Lebanon, Syrian refugee women and girls of diverse backgrounds continue to confront widespread and systemic gender inequality, which manifests in less access to resources, services, and opportunities, as well as higher risks of violence, abuse, and exploitation. This research brief summarizes key gender analysis findings from UN and humanitarian partner assessments in effort to raise the profile and understanding of gender inequalities amongst Syrian refugees and improve the gender responsiveness of humanitarian action in Lebanon.
Women and Young People in Peace Processes: Synergies and Cross-learning
Date: Sunday, 1 September 2019
UN Women's Regional Office for the Arab States, in collaboration with UN Women Country Offices in Iraq, Libya, and Yemen, organized a two-day meeting Women and Young People in Peace Processes: Synergies and Cross-learning, funded by the Government of Germany. The meeting was held in Beirut, Lebanon and sought to provide a space for inter-generational dialogue between women and young people from countries affected by the conflict in the MENA region, to exchange strategies that have been utilized to mitigate conflict, to broker dialogue and influence track 1 peace processes in the region. Through this exchange and dialogue, the meeting sought to identify opportunities for strategic alliances and to define common demands.

redpajama_set_name: RedPajamaCommonCrawl


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asked What is your experience with LED light strips on cars and trucks?
i was thinking about getting one of those LED light bars on the back of my jeep for looks and just to be more visible at night but i hear they cant stand the heat or cold? i see those bars with 3 or 4 of them burned out so are they worth it?
Depends a bit on where you are, but cars are pretty harsh environments for any electronics. Make sure you buy a quality led strip - not the cheapest one - and get a waterproof version, even for internal mounting. The power supply should be inside, and all the connectors should really be shrink-wrapped to keep them dry.
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Since the program's inception, between 15 and 20 Lake Forest College students from a variety of majors have conducted 10 to 12 weeks of paid research annually as RFUMS Summer Scholars. In this role, they have worked alongside graduate students, postdoctoral scientists, and health professionals to carry out original medical research in the areas of cell and molecular pharmacology, neuroscience, cell biology and anatomy, biochemistry and molecular biology, pathology, microbiology and immunology, and physiology and biophysics.
nationally renowned health sciences university was co-created by Lake Forest College's Disque D. and Carol Gram Deane Professor of Biological Sciences Shubhik DebBurman and RFUMS professors. Their intent was to give undergraduate students an edge in postgraduate programs in basic sciences and allied health professions.
This thriving program will once again place 20 talented life-science majors in as many different labs this coming summer, thanks to the long-term efforts in fostering strong relationships between the institutions by faculty mentors Assistant Professor of Biology Lynn Westley, who co-coordinates the program with DebBurman.
Pascal Accoh '12, a biology and neuroscience double major, was among the first group of Foresters chosen to work at the medical school located a few miles north of Lake Forest College. In that first summer, Accoh discovered he liked research so much he spent all four undergraduate years in the program building on his work.
His track record of research helped Accoh achieve his ultimate goal: To get into medical school. His time spent in the lab at RFU "was a big, important piece of my application packet," Accoh said. Able to show that he had experience in a basic sciences lab "helped me demonstrate to other medical schools that I was multi-faceted and an applicant who was not only interested in practicing medicine, but who could also do the research component," he said.
Since graduating from Lake Forest College, Accoh earned his MD at Southern Illinois University School of Medicine and is currently completing a residency in internal medicine at St. Louis University.
Sullivan received his PhD in biochemistry and molecular biology at Cornell University after graduating from Lake Forest College. Today, he is a postdoctoral research fellow at Seattle Children's Hospital. In this familiar lab setting, Sullivan is studying immune response and immunotherapeutic approaches to treating cancer. As a product of his research, Sullivan has authored several published papers over the past two years.
Natalie Simak '11, biology and psychology double major, received her first credit as a coauthor on a published paper in November 2009 while she was a junior at Lake Forest College. Since then, Simak has been listed as a coauthor on multiple research papers. Today, she is an anesthesiologist with University of Chicago Medicine.
In 2018, Michael Janecek '18, neuroscience and history double major, furthered that legacy of Lake Forest students earning professional publishing accolades for their research at RFU. Janecek is listed as first author on an extensive paper he coauthored with RFU neuropharmacologist Joanna Dabrowska on the role of neuropeptide oxytocin in fear and anxiety.
His experience at RFUMS "opened my eyes to the world of academic research and the excitement of creating my own questions and helped me decide that neuroscience research is what I want to do," Janecek said.
Kimberly Diah '13, neuroscience and psychology double major, is currently a fourth-year PhD student at Nova Southeastern University in Florida, where she is completing a PhD in clinical neuropsychology. As an RFU summer research scholar, she worked in the labs of Drs. Kuei Tseng and Michela Marinelli studying the impairment of the mesocorticolimbic dopamine system in relation to drug addiction liability. She eventually went on to complete her senior thesis project in Tseng's lab on the role of early adolescent drug exposure in the ventral hippocampus of male rats. A paper on the project was published in 2013 in the Hippocampusjournal.
The LFC-RFUMS Summer Scholars program is funded in part by the Rosalind Franklin University of Medicine and Science, the Gorter Family Foundation, Grace Elizabeth Groner Foundation, and the Career Advancement Center at Lake Forest College.


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Moral ethics
Anthony Wilson September 13, 2016 September 12, 2016 Being a Poet, Being a Writer, Being Creative, Life Lessons, Poems, Poetry, Poets, The Book, Writing
'I'm tired.'
'Go to sleep then,' the book says. 'There's plenty for me to be getting on with while you're gone. Put your feet up, go on. I'll be fine.'
'Can I trust you?'
'Now there's a leading question! What do you think? Have I let you down before? Don't answer that.'
'What will you be doing while I've been gone?'
'Oh, you know,' the book says, making a sweeping gesture with its hand. 'Things. Stuff. There really is plenty to be getting on with. You go and sleep. I'll be fine.'
'I had a really weird dream the other night. There was this man, who wasn't me but was, and he was a professor in moral ethics. And to pay for his child's university education he did some really naughty things.'
'I'm not your therapist,' the book says. 'I'm your book.'
'But I thought you might be, you know, interested. It gets worse.'
'I am not interested.'
'I just wondered, how, you know, I could dream something up like that, a complete story, that was so -'
'You haven't told me the complete story.'
'You said you weren't interested.'
'You're right, I'm not.' The book stretches itself, and gives a loud, comic book yawn. 'Right, I'm off,' it says. 'I'm done for the day, honestly. Time for a nap.'
'But you said I could go for a nap,' I say. 'You would be 'fine', you said. You had 'plenty to get on with', you said.'
'I lied,' the book says.
Being a Poet, Being a Writer, Being Creative, Creativity, Life Lessons, Teaching Writing, The Book, Trusting in the Process, Writing, Writing a book of poems, Writing Poems, Writing Poetry, Writing Process
Previous No one you know
Next Alone, by Tomas Tranströmer
Rebecca Adams says:
In the Talmud, it says "Do not say you will study when you have time, because you may never have time," – of course telling us to study, no matter what (a duty of holiness, growth, moral learning, and transformation). But how to write when you're tired, when you're troubled? When the things we do to pay rent, feed ourselves and our families, are so insistent, exhausting, and sometimes besmirching? — I don't know. Except – Yeats: —- "…. less soul clap its hands and sing, and louder sing, for every tatter in its mortal dress."
Perhaps that means that you need to write no matter what. And that I need to write, study, and read no matter what. However, I'm very tired…. Oh dear.
Singing is good: when one sings, there is joy, and when there is joy, there is more energy and strength. So — off to do a medley from "The Sound of Music", or "Oklahoma", and hope that the neighbours aren't obliged to hear.
Thank you — !


text:
package com.kolich.aws;

import com.amazonaws.services.sqs.model.*;
import com.kolich.aws.services.sqs.SQSClient;
import com.kolich.aws.services.sqs.impl.KolichSQSClient;
import com.kolich.common.date.ISO8601DateFormat;
import com.kolich.common.functional.either.Either;
import com.kolich.common.functional.option.Option;
import com.kolich.http.KolichDefaultHttpClient.KolichHttpClientFactory;
import com.kolich.http.common.response.HttpFailure;
import org.apache.http.client.HttpClient;

import java.net.URI;
import java.util.Date;

public class SQSTest {

	private static final String AWS_ACCESS_KEY_PROPERTY = "aws.key";
    private static final String AWS_SECRET_PROPERTY = "aws.secret";

	public static void main(String[] args) throws Exception {

		final String key = System.getProperty(AWS_ACCESS_KEY_PROPERTY);
		final String secret = System.getProperty(AWS_SECRET_PROPERTY);
		if (key == null || secret == null) {
			throw new IllegalArgumentException("You are missing the "
				+ "-Daws.key and -Daws.secret required VM "
				+ "properties on your command line.");
		}

		final HttpClient client = KolichHttpClientFactory.getNewInstanceNoProxySelector();

		final SQSClient sqs = new KolichSQSClient(client, key, secret);

		URI queueURI = null;
		final Either<HttpFailure,CreateQueueResult> create = sqs.createQueue("----__________");
		if(create.success()) {
			System.out.println("Created queue successfully: " + create.right().getQueueUrl());
			queueURI = URI.create(create.right().getQueueUrl());
		} else {
			System.err.println("Failed to create queue: " + create.left().getStatusCode());
		}

		final Either<HttpFailure,ListQueuesResult> list = sqs.listQueues();
		if(list.success()) {
			for(final String queueUrl : list.right().getQueueUrls()) {
				System.out.println("Queue: " + queueUrl);
			}
		} else {
			System.err.println("Listing queues failed.");
		}

		for(int i = 0; i < 5; i++) {
			final Either<HttpFailure,SendMessageResult> send =
				sqs.sendMessage(queueURI, "test message: " +
					ISO8601DateFormat.format(new Date()));
			if(send.success()) {
				System.out.println("Sent message [" + i + "]: " +
					send.right().getMessageId());
			} else {
				System.err.println("Failed to send message.");
			}
		}

		for(int fetched = 0, error = 0; fetched < 5 && error == 0;) {
			final Either<HttpFailure,ReceiveMessageResult> messages = sqs.receiveMessage(queueURI, 10, 5);
			if(messages.success()) {
				fetched += messages.right().getMessages().size();
				System.out.println("Loaded " + messages.right().getMessages().size() + " messages.");
				for(final Message m : messages.right().getMessages()) {
					System.out.println("Message [" + m.getMessageId() + "]: " + m.getBody());
					final Option<HttpFailure> deleteMsg =
						sqs.deleteMessage(queueURI, m.getReceiptHandle());
					if(deleteMsg.isNone()) {
						System.out.println("Deleted message [" + m.getMessageId() + "]");
					} else {
						System.err.println("Failed to delete message: " + m.getReceiptHandle());
					}
				}
			} else {
				error = 1;
				System.err.println("Loading messages failed.");
			}
		}

		System.out.println("No messages should be on queue... long poll waiting!");
		final Either<HttpFailure,ReceiveMessageResult> lp = sqs.receiveMessage(queueURI, 20, 5);
		if(lp.success()) {
			System.out.println("Long poll finished waiting successfully.");
		} else {
			System.err.println("Failed to long poll wait.");
		}

		final Option<HttpFailure> delete = sqs.deleteQueue(queueURI);
		if(delete.isNone()) {
			System.out.println("Deleted queue successfully: " + queueURI);
		} else {
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redpajama_set_name: RedPajamaGithub


text:
Charles Eugene Fager (nacido en 1942), conocido como "Chuck Fager" es un activista estadounidense, autor, editor, y es miembro prominente de la Religious Society of Friends. Es conocido por su trabajo en el Movimiento de Derechos Civiles y en el Movimiento a favor de la Paz en 1960. Entre sus escritos figuran ensayos sobre religión y política, obras humorísticas, ficción para adultos y para adolescentes. Su obra más conocida es "Selma 1965: The March That Changed the South" (La marcha que cambió el Sur), centrada en el Movimiento a favor del Derecho al Voto de 1965. Fue director de la "Casa de los Cuáqueros" en Fayetteville, Carolina del Norte, un proyecto en pro de la paz, cerca de Fort Bragg, importante base del Ejército de los Estados Unidos.

Primeros años
Charles E. Fager nació en Kansas, en una familia católica. Es el mayor de once hermanos. Se crio en distintas bases de las Fuerzas Aéreas Estadounidenses.

Educación
Mientras realizaba sus estudios secundarios, Fager abandonó el catolicismo y durante algunos años se consideró a sí-mismo ateo. Sin embargo, le interesaba la religión, y recibió una notable influencia de la obra de C.G. Jung, que le llevó a prácticas religiosas ortodoxas.

Activismo
Fager se trasladó a Atlanta, Georgia a finales del verano de 1964, y pronto se convirtió en activista del movimiento de los derechos civiles.
En diciembre de 1964 se unió al equipo de la Southern Christian Leadership Conference (SCLC), primero en Atlanta y luego en Selma, Alabama.
Participó en la campaña sobre el derecho al voto de 1965, organizada por el Dr. Martin Luther King, Jr. Durante ese periodo, Fager fue arrestado en tres ocasiones y pasó una noche en prisión, en la misma celda que el Dr. Martin Luther King, Jr.
Fager se marchó de Selma a principios de 1966. Participó en varias manifestaciones pacíficas contra la guerra del Vietnam. En esas fechas, la policía le detuvo dos veces.

Participación en la Sociedad de Amigos
Afiliación

Fager trabajó en el "Friends World Institute" y conoció a personas de creencias quáqueras, que trabajaron con él.

Trabajó como instructor de jóvenes en la universidad, de 1966 a 1967. En 1969 se unió a la "Friends Meeting at Cambridge", Massachusetts, mientras estudiaba en Harvard Divinity School. Desde entonces, ha participado en las sucesivas reuniones de esta institución.

Publicaciones Profesionales y Peregrinación

En la escuela secundaria, a mediados de la década de 1950, Fager recibió críticas por escribir una colección de artículos ilegales, en la que se burlaba de los maestros y las autoridades escolares. Ha sido escritor desde entonces.
Comenzó a trabajar como periodista en la universidad, y en 1967 publicó su primer libro, "White Reflections On Black Power", seguido de "The Poor Peoples Washington Campaign".
A pesar de no permitirle ganarse la vida adecuadamente, la necesidad de escribir era irresistible, y dejó la vida académica.
Desde Massachusetts, Fager se trasladó en 1975 a San Francisco, donde ejerció como periodista independiente a tiempo completo en la zona de la bahía.
Entre otros temas, escribió sobre el excongresista Pete Paul McCloskey. En 1978, Fager se mudó a la zona de Washington DC, y posteriormente, McCloskey lo contrató como investigador de personal para la Marina Mercante de los EE. UU. de A., la Casa Marina y la Comisión de Pesca.
Conservó el puesto hasta comienzos de 1981, cuando McCloskey se presentó sin éxito a las elecciones para el Senado. A pesar de su amistad con McCloskey, a Fager no le gustaba el Capitolio como lugar de trabajo, y estaba dispuesto a dejarlo atrás.
En 1985, Fager comenzó a trabajar para el Servicio Postal de los EE. UU., primero como Cartero Rural sustituto, y luego como Manipulador de correo, hasta mediados de 1994. El sueldo y las condiciones de dichos puestos de trabajo eran satisfactorios para él y su familia (cuatro hijos). Durante estos años de actividad, Fager siguió siendo escritor (se inspiró en esta experiencia para su segunda novela de misterio, "Un-Friendly Persuasion"). En 1979 fundó "Kimo Press", que publica literatura Quáquera, de la que es autor en su mayoría. A partir de 1981, también ha sido editor independiente, periodista de investigación y ha prestado sus servicios en un diario quáquero llamado "A Friendly Letter", puesto que desempeñó hasta principios de 1993. Fundó una revista titulada "Quaker Theology" en 1999.
Después de dejar el servicio postal en 1994, fue contratado para crear un Programa de Cuestiones en Pendle Hill, un centro de estudios en Wallingford, Pennsylvania. A partir de entonces, en 1997, se trasladó a Bellefonte, PA, donde volvió a ser escritor independiente, e impartió cursos de Redacción para los negocios en la Penn University.
Después de los ataques del 11 de septiembre de 2001, accedió a ocupar el puesto de Director de la Casa Quáquera en Fayetteville, NC.
En sus escritos, Fager ha aportado diversas respuestas a los intereses comunes. Ha redactado informes en especial sobre temas sociales de actualidad, como el movimiento a favor de los derechos civiles, las últimas guerras, el militarismo, la tortura y la religión, centrándose especialmente en los Quáqueros, la Sociedad de Amigos y la Historia, en particular para los lectores más jóvenes.

Organizaciones

Entre 1996 y 2002, Fager también ocupó el cargo de Secretario en la Comunión de los quáqueros en las artes. También fue Secretario de la mesa redonda quáquera de 2001 sobre la Paz. Desde principios de 2005, ha formado parte de la Iniciativa quáquera para erradicar la tortura.

Vida personal
Fager se ha casado y divorciado en dos ocasiones. Tiene cuatro hijos adultos y un número creciente de nietos.

Referencias

Activistas de Estados Unidos
Ensayistas de Estados Unidos
Pacifistas
Cuáqueros
Escritores de literatura infantil de Estados Unidos
Alumnado de la Universidad de Colorado
Alumnado de la Universidad de Harvard

redpajama_set_name: RedPajamaWikipedia


text:
TeO celebrates the return of His Majesty
Integrated Telecommunications Oman (TeO), the latest name in the telecommunications industry of the Sultanate, organised celebrations with gusto to mark the homecoming of His Majesty Sultan Qaboos bin Said in sound health. The TeO office was decorated in bright national colours and the joyful Omani and expatriate employees created a festive atmosphere.
Mr. Gurkan Ozturk, CEO of TeO, hailed the sound health of His Majesty: "We are all jubilant over the return of His Majesty and pray for his well-being and good health. His Majesty has made Oman a nation of peace and prosperity and a role model for many nations around the world. On this auspicious occasion, we are happy to announce a special bonus for our staff. This is a small gesture on our part to demonstrate our happiness and compliment all our employees who have total loyalty, admiration and respect for the beloved leader of Oman".
"As the youngest telecom player, TeO is energized by the grand vision of His Majesty for making the Sultanate home to the "Digitally-connected Knowledge Society". We seek to be an essential contributor to this vision by bringing innovative and smart communications solutions for our customers", Mr. Ozturk adds.
Integrated Telecommunications Oman S.A.O.C., a 100% Omani company, is the first private CLASS I licensee international gateway operator, a mobile virtual network operator (MVNO) and the first-of-its-kind over-the-top service provider in the Sultanate of Oman.
Renna Mobile adds nine new Suzuki Grand Vitara SUVs to its sales fleet
Renna Mobile wins International Award as "Most Successful MVNO" at The MVNO World Congress in France
TeO acquires 100% share of Renna Mobile (Majan Telecommunications)
TeO hosts Iftaar party to celebrate acquisition of Renna Mobile
TeO sponsors Graduation Ceremony for ITA's Sas Centre for Entrepreneurship


text:
Chunk (Chester P. Runk) is a fictional character appearing in comics published by DC Comics. He first appeared in The Flash (vol. 2) #9 (February 1988) and was created by Mike Baron and Jackson Guice.

Chester P. Runk appears in live-action by Brandon McKnight in the CW Arrowverse television series The Flash starting in the sixth season.

Fictional character biography
Maverick physicist and engineer Chester P. Runk had no living relatives. Chester was a child prodigy and an M.I.T. graduate, but he also had serious psychological problems. According to Cyborg, at the age of twenty-four, Runk had developed a "matter transmitting machine", a primitive long range teleportation device. Due to a lack of sensible safety procedures on Runk's part, his machine imploded and became a part of his body after his first test of its long range teleportation capabilities. The accident made him superstrong and resilient, and gave him the power to teleport anywhere he wished on Earth and off. He was also forced to physically absorb forty-seven times his own weight in superdense matter like diamonds, just to keep the machine from eating him or collapsing him down to a dimension lower than the one he had access to. Chester had become a human black hole. Runk came to the Flash's (Wally West) attention during a crime spree where he was seen literally eating diamonds to feed the machine. He was also seen stealing expensive high tech research equipment. Chunk appears to have been diagnosed as mentally unstable before the accident, and had been seeing a therapist named Jarret Parker for years.

The Void
Chester could access a local pocket dimension he called "the Void", a barren rocky waste that is home to strange prehistoric creatures. He had sent many people there over the three-year period since his accident, the first being Jarret Parker Ph.D., his former psychiatrist, and Karin Preus, a woman who had rejected his advances. Many dozens of innocent bystanders, many who were guilty only of annoying Chunk, were stranded and forced to eke a living out of the Void's severe landscape, by learning how to hunt the lizards, insects and giant winged reptiles that make their homes in the canyons. Some grew food using the guano of the winged reptiles to cultivate seeds taken from some of the many cars Chunk had taken. However, a majority of the victims Chunk sent into the void were murderers, sadists and criminals. Some of the roving bands of criminals had even turned to cannibalism.  Chester brought Wally there at the end of their second fight where he joined up with a group of decent-minded survivors. Wally soon convinced Chunk that he would be hailed for his scientific discovery if he would just send all his victims back to Earth. Chester revealed to Wally that he could not control himself when he left the Void; the partially formed singularity simply threw him out whenever it got hungry. Chester agreed to do so, and further police investigations declared him innocent of any charges.

He was unable to bring all of his victims back right away, though he never stopped trying. Finally, they all returned to Earth during a going away party thrown by the Rogues for Captain Cold. Wally West had been invited as a gag by the Trickster, and he arrived with Chunk, but the victims destroyed the hotel ballroom where the party was being held, nearly instigating a riot in the process. Wally and The Rogues were able to assist the police in subduing the mob before they got out of hand.

In a backup story in The Flash (vol. 2) Annual #2, a team of scientists approaches Chunk, asking to study the Void. Chunk sends one of the scientists there (humorously, the scientist was unprepared). As the scientist shifts through several dimensions, including the one Wally was in, one with razor-sharp spikes, and even one with no air, he returns to Earth relatively unharmed. He comments that there seemed to be a great interdimensional cataclysm, and Chunk's powers give him access to the remains. While this is a vague allusion to Crisis on Infinite Earths in which the DC Multiverse was destroyed, an official connection was never established.

Waste removal and other battles
"Chunk" later worked as a "waste removal specialist" because he believed "everyone has something they'd like to disappear". He was close friends with Wally West, and for a while employed Wally's mother as his secretary. Due to the wealth rolling in from his new business, he was able to buy Wally's former mansion, and moved into it along with a great deal of distantly related relatives. During this time, Chester is confronted with one of the few things he cannot remove, a large tumor from the brain of a very sick woman. Against her explanations of offering money, Chester explains that since he cannot actually see the tumor, he cannot remove it, and even if he were able to locate its exact position via x-rays, its disappearance would result in air rushing to fill the space it formerly inhabited, imploding the woman's head and killing her. The woman leaves, but not without help, a friendly visitor offers to give her a ride home.

Chester is engaged to Wally's ex-girlfriend Connie Noleski.

At some point during this period, he was allied with Amanda Waller's ad hoc team of Shadow Fighters, a diverse group brought together to fight Eclipso. Armed, he would join the final battle and even confront Eclipso face to face.

During Blacksmith's campaign to take over the Twin Cities, a rogue named Plunder shot Chunk with the only thing that could hurt him, a bullet laced with White Dwarf Matter (the substance Atom uses to shrink). The bullet wound opened up a vortex within his body, which sucked in everything around him, including people and light. The Central City Police Department called the KCPD in order to enlist the Flash's help, but he also ends up being sucked into the vortex. The situation was resolved when Wally recovered the bullet from the vortex in Chunk's body, which allowed him to quickly recover from his wound.

New 52
A New 52 version of Chunk is reintroduced as an classmate/friend of Wallace West/Kid Flash.

Powers and abilities
 Chester has the ability to absorb matter and expel it into a pocket dimension called the Void.
 He has also exhibited super-strength and limited invulnerability, and was able to easily survive being struck by a small commuter van, and then used his bare hands to rip off its doors.
 He's immune to most physical attacks; any weapons used against him are absorbed by his body.
 Chunk could unconsciously manipulate local gravimetric fields and draw matter towards him.
 The only ballistic projectiles that have been shown to hurt Chunk are bullets coated or laced with White Dwarf Star material, the same substance that allows the Atom to shrink.

Other versions
In this alternate future, Chunk works at S.T.A.R. Labs with Flash ally Tina McGee. He is aged and thinned by and finally killed by super-criminals in order to force cooperation from his colleagues. This future is framed in a present-day story where Chunk is invited as a special guest to a Flash-Day celebration.

In other media
Chester P. Runk appears in the Arrowverse series The Flash, portrayed by Brandon McKnight. Introduced in season six as a recurring character before being promoted to series regular for seasons seven, eight and nine, this version is a self-taught, brilliant, yet socially awkward non-overweight scientist capable of building sophisticated devices out of discard junk and scraps who was inspired by his inventor father Quincy P. Runk (portrayed by Milton Barnes), who died in a car accident in the 1990s. In his first appearance, Chester built a machine capable of opening black holes, only to accidentally create one that fused with his consciousness; leaving him in a catatonic state while the black hole itself opened in places that held great emotional significance to him. Eventually, the Flash rescues his consciousness from the black hole and places it back into his body, ending the threat. After stabilizing in a special machine built by S.T.A.R. Labs for several weeks, Runk is able to get his life back together as well as join Team Flash, providing assistance via his scientific expertise.

References

External links
Those who ride the lightning: Chunk Profile
Crimson Lightning  - An online index to the comic book adventures of the Flash.
GCD Project: Flash vol. 2 #9
DCU Guide: Chester P. Runk Profile
DCU Guide: Chester P. Runk Chronology
DCDatabase: Chunk
DCU Guide: Flash vol. 2 #177
DCU Guide: Eclipso - The Darkness Within #2
DCU Guide: Eclipso #11
Those who ride the lightning: Connie Nolenski
Flash Storylines: 1987–2006

Comics characters introduced in 1988
DC Comics male superheroes
African-American superheroes
Fictional inventors
Characters created by Mike Baron
Characters created by Jackson Guice
DC Comics characters with superhuman strength
DC Comics metahumans
Flash (comics) characters


This is a refreshing salad with an amazing combo of sweet, juicy cantaloupe, intriguing spicy smoky chorizo, and distinctly peppery rocket salad, dressed simply with olive oil.
Heat a small skillet over medium heat. Add the chorizo slices and cook for 1-2 minutes or until the slices are crispy. Let cool, then break into small pieces.
Shave off ribbons of cantaloupe, using a vegetable peeler or mandoline. Arrange arugula leaves and cantaloupe ribbons on two serving plates. Sprinkle the chorizo and crushed pink peppers over. Drizzle olive oil over salads.
What a wonderful combination of fresh flavors in this beautiful dish, Angie! It looks so spring-inspired and delicious. Thanks for sharing!
Love the chorizo with the cantaloupe - makes a nice change from proscuitto, even though that is tasty as well.
Love this salad. Beautiful ribbons.
A splendid salad! Fresh and flavorful.
What a delightful and unique salad - the flavours of the cantaloupe and chorizo compliment each other beautifully.
WOW!! A beautiful plate of salad! Wish I could have some now!!
That's very creative, healthy and looks fabulous! Love it.
I have been eyeing the cantaloupes and you have beat me to them. This recipe does make great use of this terrific fruit. Love the sweet and salt combo. I am sure the chorizo adds some wonderful flavor to this. Well done!
So healthy and gorgeous at the same time. This is spectacular Angie.
Such a pleasing palate..lovely color and beautiful ribbons! So refreshing..
What a great combo of flavours, Angie, and it looks amazing! I LOVE the surface you are shooting on, so rustic and beautiful. I've seen it in other shots and have meant to comment but forgot!
Not only is this salad beautiful, but I love the sweet spicy salad idea.
These plates of salad looks so healthy and refreshing... this is a prefect springtime recipe to get in shape!
Very interesting use of the cantaloupe! I just love anything with chorizo in it!
This salad looks wonderful. You can never go wrong with arugula.
You had me at Cantalope Ribbons! Beautiful salad, and so creative.
What a brilliant combination! And lovely pictures too.
Interesting combination of flavors, I know I'd love it, different but looks so good! Very pretty salad.
What brilliant interpretation of the more common cantaloup and prosciutto! I love the addition of the tangy rocket leaves and pink peppercorns. This will be spectacular when the farmers'markets are selling sweet, summer melons! This might end up on our summer gourmet menu :) Thank you, Angie!
At first I thought this was pasta.... What a great idea to make salad out of melons!
What an amazing salad! I bet the combination of melon and chorizo is fantastic!
This looks absolutely delicious !!
This is absolutely lovely. I want to try this immediately!
This is so beautiful - and such a wonderful light lunch!
Delicious contrasting flavors yet so simple to do, awesome! Beautiful photos!
Angie I'm jumping up and down in my seat! This is so wonderful, beautiful and creative. I can't wait to try this salad. I wish I could spend a week with you in your kitchen. I just want to soak up the creativity. Thanks and have a great weekend.
What an excellent combination of flavors and textures. It looks beautiful too!
I love the sweet and salty flavors going on in this salad! Stunning, Angie!
What a lovely combination! Love parma ham and cantaloupe but will probably love this even more because I'm nuts about chorizo. Love the photos.
That dish is absolutely beautiful! I'm not sure where to start. :) Just like Anne wrote, I also thought that it was a pasta dish at first. WOW! Your cantaloupe ribbons are really a piece of art. Very impressive and I love the presentation.
That is gorgeous! I have been craving melon lately--must be longing for spring--and this is the perfect dish for it.
Luce absolutamente hermoso y delicioso ,me encantan las pastas ,abrazos hugs,hugs.
This is a new idea of eating melon! Beautiful ribbons!!
I've always loved cantaloupes with prosciutto so I'm imagining this would be just as delicious. And instead of a starter, it's become a main with the pasta ... great for a warm weather lunch!
I kept seeing this on foodgawker and was so intrigued by it...it sounds perfect for summer!
You are so creative, Angie. I love this salad! Healthy, tasty and so pretty to the eye! Perfect for a summer lunch.
BTW: I made your pineapple/apple salsa. It was wonderful!
Awesome idea of a dish Angie! I never thought of combining cantaloupe Arugula and choriz (and olives). the freshness of the fruit and the other spicy ingredients, very delicious! Great post and awesome presentation!
i see that you have 2 plates there..dont mind me taking one plate away for myself? LOL!
This looks like such a great salad! I am going to have to try it.
I love recipes with few ingredients that pack big flavor. What a nice balance between sweet and spicy.
What a great recipe - so inventive. Those ribbons are divine.
Such a pretty and genius combination...ribbons of sweet goodness paired with the spiciness of the chorizo!
This looks just like pasta! What a pretty and unique salad!
Amazing! If I hadn't seen the title I would have sworn this is pasta with chorizo! Thanks for sharing this extraordinary recipe.
what a delicious and intriguing combination. One I would never have thought of which is why I love your posts.
What a wonderful salad. I've tried chorizo once and didn't like it but I can think of so many other things using the melon and rocket, which is a great combination. Congratulations on the Top 9.
What an absolutely lovely salad! I've had chorizo with cantaloupe before but never like this as a salad with arugula. This sounds wonderful! I can see why it made the Foodbuz Top 9! Congrats!
chorizo and canteloupe is a winning flavor combination, A great summer salad. Awesome.
Beautiful photos. Such a gorgeous, bright, fresh salad.
I never would have thought to use cantaloupe for ribbons, but I love it and can't wait to try this!
Canteloupe ribbons - what a brilliant idea! I've seen many zucchini ribbons in my day :) but not canteloupe!
What an unlikely but delicious combination Angie! The cantaloupe ribbons are gorgeous!
Angie, I just wanted to let you know I made this for a birthday dinner party last night and it was delicious! I made a vinaigrette with a little champagne vinegar and a touch of sugar and Aleppo pepper and dressed the melon and topped the arugula with the melon and then the chorizo. Our melons aren't the best yet but it was still wonderful. Thank you!
Gorgeous photos and fantastic salad!
It looks so beautiful, healthy and delicious! I will have to try this soon.
What a gorgeous salad--I love the way you cut the cantaloupe into ribbons!
such an elegant and refreshing looking salad!
@SavoringTime in the Kitchen Susan, I am so happy to hear that! Thanks!
This a very appropriate salad for this season! Fresh and inviting full of colors!
What a great idea in terms of the cantaloupe. You rarely see it used in this way, and it's very elegant for a salad.
This sounds like the perfect spring starter or side salad!
What a beautiful salad - I bet this combination is super tasty!
I would have never thought about this combination of chorizo and cataloupe! Sounds great!
i never thought about making cantaloupe into ribbons and putting them into a salad! the sweetness of the fruit complements the chorizo, i'm sure!
Those cantaloupe ribbons are so pretty!
the presentation of this dish is what has really captured my imagination. I love the look of the melon ribbons. It won't be too long before locally grown cantaloupes will be available at our markets, and I'll be thrilled to try your recipe.
What an absolutely lovely and decorative salad...beautiful!


Because who doesn't love a good special edition?
Today on Drive Wire we explore the ever-expanding Jeep Wrangler special edition line-up.
According to reports, Jeep will be unleashing six special edition wranglers before the JK bids us farewell. Although Jeep may be looking to a new generation Wrangler, they release the current gen is selling well and they want to send it off with some fancy decals and upgrades.
The first two special editions to grace the jeep community will be the Wrangler Sport Freedom edition and the Wrangler Sport Winter edition. The Freedom edition will come with all typical American goodies like a sweet American Flag decal on the front fender, a freedom star decal, and much more. The Winter edition will come with slightly pricier options like LED headlights, a hardtop, remote start and other cold-weather orient accessories.
Although this may seem like enough special edition wranglers to last the duration of the JK's life, Jeep plans to release the Wrangler Sport Big Bear, the Wrangler Rubicon Recon, the Wrangler Chief and the Wrangler Smoky Mountain before JK-production ends.
With names like these, we wonder if Jeep just started throwing darts at a board. Whatever the case may be, we are excited for some special editions.
Because 640hp is just not enough.
CEO Dr. Ralf Speth made the announcement at the Los Angeles Auto Show.
It's awfully dark for a kids movie.
Two legends, two careers, countless memories.


text:
Ground Zero mosque — a terror act in slow motion!
By Shavana Abruzzo Posted on June 7, 2010
When a non-Muslim American can open and operate a strip joint in Mecca, a pork store in Islamabad or a gay bar in Tehran — with the full cooperation of Islamic authorities — then, perhaps, the thought of a mosque near Ground Zero might not be nauseating.
When Manhattan's Community Board 1 voted near-unanimously on May 24 for the construction of an Islamic cultural center and mosque two blocks from where fanatical Muslims crashed two airliners into the World Trade Center nine years ago, it demonstrated an indecent allegiance to a community which is so insensitive to that day's carnage that it wants to open a mosque at the site.
The mosque — and public record shows that mosques around the world have been abused to promote terror activities — is being pushed full steam ahead by the New York-based American Society for Muslim Advancement, a cocky group founded in 1997 by Daisy Khan and her husband Feisal Abdul Rauf Khan to promote "an authentic expression of Islam."
Thanks but no thanks, Mr. and Mrs. Khan, for the world has had it up to here with Islam's "authentic expressions," and none of them are impressive!
Critics, who think that decrying a mosque in New York is un-American, should note Mr. Khan's anti-Americanism: He blamed the US for the 9/11 attacks in a Sept. 30, 2001 interview with "60 Minutes," charging that "United States' policies were an accessory to the crime that happened."
His wife has said about the Ground Zero mosque project, "We decided we wanted to look at the legacy of 9/11 and do something positive."
Positive would be telling New Yorkers that Muslims are so remorseful about 9/11 that there aren't enough tears left in the world to express their sorrow.
Positive would be calling for a global convention on Islam and its human time bombs.
Positive would be to understand that a mosque does not belong — nor is welcome — at Ground Zero.
The legacy of 9/11 is that the U.S. is on the radar of our sworn enemies who want nothing more than to eradicate this great land, which has moved hell and earth to welcome and accommodate people of all faiths.
What has separated this nation from others — her heart, her largesse, her congeniality — has also become her Achilles heel as she tries to steer a conniving course set forth by Muslim extremists whose contribution to modern-day humanity is the export of terrorism.
Our awkwardness in addressing Islamo-fueled terrorism has emboldened individuals and splinter groups to conduct self-inspired acts of terror. Now, even Muslims who are US citizens are jumping on the Jihad bandwagon to kill fellow Americans!
We were reintroduced to that deadly desire last month when 30-year-old Pakistani immigrant Faisal Shahzad — a U.S. citizen for just a year — decided to blow up Times Square so that thousands of innocent men, women and children would die.
If, as they claim, Mr. and Mrs. Khan are committed to "building bridges between Muslims and Americans," then let them axe their plans for a mosque at Ground Zero. Anything less means that they want to rub New Yorkers' faces in the ashes of their murdered loved ones. And, have a formal place for Muslims to pray and gloat in, and gloat and pray in — fives times a day, every day. That amounts to a terror attack in slow motion!
Op-Ed: A once-in-a-generation chance to reimagine the BQE
Op-Ed | The future of women's rights and health
Op-Ed | Crystal's Corner: Accountability matters. Why do we exempt the worst landlords?
Op-ed: Short-term rentals provide economic benefits to local small businesses


text:
Ravens' Steve Smith says he'll play next season
Written By Arthur Weinstein
(Getty Images) https://images.performgroup.com/di/library/omnisport/19/d8/steve-smith_1mw0hka5g3c2c19cz0s2syhobu.jpg?t=-633335286&w=500&quality=80
Steve Smith's season ended with the Ravens' 35-31 loss to the Patriots Saturday night, but the veteran wide receiver's career will go on.
Smith is 35, which is ancient in wide receiver terms. When the longtime Panthers star signed a three-year, $11 million contract to join the Ravens for this season, some speculated he might play one more season and then retire.
Smith said on Instagram Sunday he will return in 2015.
#ravensnation thank you so much for embracing me I hoped for a good season and now I look back it was a GREAT season this old man played for you and my teammates I've enjoyed every moment and couldn't have asked for a better fan base. Look forward to a better season next year and watch us go WIN IT ALL. #agent89 Out. #stevesmithsr #playlikearaven #purplebirdgang
A photo posted by Ace and SmittySr (@aceandsmitty) on Jan 10, 2015 at 7:02pm PST
Smith posted respectable numbers in his first season in Baltimore (79 catches, 1,065 yards, six touchdowns). He showed against the Patriots he can still play at an elite level. Covered by shutdown cornerback Darrelle Revis, Smith beat Revis on a 9-yard touchdown catch in the first quarter. Revis was also flagged for a holding and pass interference call on two other plays against Smith, who finished with three catches for 44 yards.
The Ravens' other starting wide receiver this year, Torrey Smith, will become an unrestricted free agent in March, making Steve Smith's vow to return good insurance for the club.
Smith is reaching elite territory in terms of lifetime statistics. He's 14th in all-time receiving yards, with 13,262, and 18th in all-time receptions (915).


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L'antico Mercato di Siracusa è un edificio del 1900 sito in Via Trento, a ridosso del Tempio di Apollo in Ortigia.

Storia

L'area su cui sorge l'antico Mercato venne acquistata dal comune nel 1885 laddove erano ancora presenti le mura spagnole. Qui venne decisa la costruzione del mercato della città. I lavori iniziarono il 20 luglio 1899 e si conclusero nel 1900.

L'antico Mercato ha svolto la funzione di principale di mercato cittadino fino alla fine degli anni ottanta, quando venne deciso il trasferimento delle attività di rivendita ittica, agroalimentare e di artigianato locale nella retrostante e più spaziosa via Emanuele De Benedictis, da allora sede dell'odierno mercato di Ortigia. In seguito a ciò, l'antico Mercato fu oggetto di un restauro conclusosi nel 2000. Da allora, ospita nel corso dell'anno eventi di diversa natura, tra cui il mercato degli agricoltori a cadenza domenicale (sospeso nel periodo estivo) e diverse rassegne musicali e culturali.

Caratteristiche
L'edificio ha le caratteristiche di un mercato coperto e richiama il Mercato delle vettovaglie di Livorno. È composto da un porticato di 24 arcate e 36 finestre, ad uso delle botteghe che popolavano l'edificio, con una superficie di 1500 m². L'interno è costituito da un cortile a pianta rettangolare con una fontana ornamentale.

Note

Altri progetti

Architetture di Siracusa
Mercati coperti d'Italia


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Top 10 Books for Older People
With the nights soon drawing in, many will be looking for something new to read. In this blog, we list our top 10 books to keep you entertained through the winter months.
Current: Top 10 Books for Older People
No matter fact or fiction, reading is a hobby that is good for people of all ages, but especially those in later life.
From boosting brain power to reducing stress, reading is a pastime that's not just enjoyable but also beneficial for your health. Read all about the many benefits here. Read on to find out our top 10 recommended books to keep your brain healthy and entertained through the winter months.
Finding Freedom by Omid Scobie and Carolyn Durand
Finding Freedom goes beyond the headlines to reveal unknown details of Prince Harry and Meghan's life together, dispelling the many rumours and misconceptions that plague the couple on both sides of the pond. As members of the select group of reporters that cover the British Royal Family and their engagements, Omid Scobie and Carolyn Durand have witnessed the young couple's lives as few outsiders can.
The Little Book of Senior Moments by Freddie Green
…you decide it's time to pull up your socks, and realise you forgot to put any on. If this sounds all too familiar, then this book will have you in stitches!
The Shopkeeper's Daughter by Lily Baxter
Set in June 1944, The Shopkeeper's Daughter is based on the life of Ginnie Travis. Ginnie is working in her father's furniture shop, when the continued bombing raids and her sister Shirley's untimely pregnancy force the two girls to go and stay with their aunt in Shropshire. After falling in love, Ginnie discovers her loved has a fiancé and ends the relationship.
Then news of their father's death in an air raid reaches them. With the family left almost penniless and Shirley and her child to provide for, Ginnie is responsible for them all. And when the shop comes under threat, she is even more determined to make it succeed and build a new life for herself and her family.
The famous Nightingale tells a tale of two sisters who despite their differences, have always been close. Younger, bolder Isabelle lives in Paris while Viann is content with life in the French countryside with her husband Antoine and their daughter. But when the Second World War strikes, Antoine is sent off to fight and Viann finds herself isolated, so Isabelle is sent by their father to help her. The sister's relationship is tested beyond belief – this book is sure to leave you breathless.
At first sight, Ove is almost certainly the grumpiest man you will ever meet. He thinks himself surrounded by idiots – neighbours who can't reverse a trailer properly, joggers, shop assistants who talk in code, and the perpetrators of the vicious coup d'etat that ousted him as Chairman of the Residents' Association. He will persist in making his daily inspection rounds of the local streets.
But isn't it rare, these days, to find such old-fashioned clarity of belief and deed? Such unswerving conviction about what the world should be, and a lifelong dedication to making it just so? In the end, you will see, there is something about Ove that is quite irresistible...
On a summer's day in 1596, a young girl in Stratford-upon-Avon takes to her bed with a fever. Her twin brother, Hamnet, searches everywhere for help. Why is nobody at home? Their mother, Agnes, is over a mile away, in the garden where she grows medicinal herbs. Their father is working in London. Neither parent knows that one of the children will not survive the week.
The Alchemist tells the story of Santiago, a young shepherd living in the hills of Andalucia. Santiago feels that there is more to life than his humble home and his flock. One day he finds the courage to follow his dreams into distant lands, each step galvanised by the knowledge that he is following the right path: his own. The people he meets along the way, the things he sees and the wisdom he learns are life-changing.
With Paulo Coelho's visionary blend of spirituality, magical realism and folklore, The Alchemist is a story with the power to inspire nations and change people's lives.
Remarkable Creatures by Tracy Chevalier
Mary Anning may be young and uneducated, but she has "the eye". Scouring the windswept Jurassic coast near Lyme Regis, she find the fossils nobody else can, making discoveries that will shake the scientific world of the early 19th century. But science is a male-dominated arena, and there are many who disapprove…
She finds an unlikely champion in prickly Elizabeth Philpot: unmarried, middle-aged and middle class, and a fellow fossil enthusiast. If they can weather differences in their age and standing, and overcome professional envy, will true friendship prove the rarest find of all?
Penguin's Poems for Life by Laura Barber
Taking its inspiration from Shakespeare's idea of the "seven ages" of a human life, this new anthology brings together the best-loved poems in English to inspire, comfort and delight readers for a lifetime.
Ranging from Chaucer to Carol Ann Duffy, via Shakespeare, Keats, and Lemn Sissay, this book offers something for each of those moments in life – whether falling in love, finding your first grey hair or saying your final goodbyes – when only a poem will do.
Prime of Life by P.D. Bekendam
Prime of Life tells the story of Ben, a previous cardiothoracic surgeon before he suddenly abandoned his career and became a janitor at a retirement facility. Now, other than dealing with minor problems such as an unhealthy obsession with prime numbers, an inept boss, and a feud between two cantankerous retirees, he lives a relatively stress- free life. There is even hope for romance when an attractive podiatrist shows an interest in him. But it is not long before his past catches up with him and his carefully protected world begins to unravel.


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Bulletin Board, News, Politics, Where The Pols Are -- Calendar
Where The Pols Are, July 9 – Update
July 9, 2018 7:00 AM·
Governor Cuomo is in New York City.
Mayor de Blasio will appear live on NY1's Inside City Hall.
10:30 AM Cynthia Nixon and Jessica Ramos (13th district challenger against Sen. Jose Peralta, a member of the IDC) to announce cross-endorsement in Queens. 35-51 81st Street, Jackson Heights
2:00 PM Governor Cuomo makes a reproductive rights announcement. Lieutenant Governor Kathy Hochul will be in attendance. Manny Cantor Center, 197 E Broadway, New York, NY
7:00 PM Sen. Jeff Klein birthday party fundraiser. F & J Pine Restaurant, 1913 Bronxdale Ave, Bronx, NY
You Should Read:
Where The Pols Are, January 2 Where The Pols Are, September 18 Where The Pols Are, 12/27 Where The Pols Are, July 13 — Dockless bikes launch
Tags: Governor Andrew Cuomo, Jeff Klein, Mayor Bill de Blasio, Politics
Author: Michael Benjamin Michael Benjamin is a public affairs consultant and an editorial board member at The New York Post. He is a former contributing columnist to the NY Post, City and State NY and other publications. He is a former Member of the New York State Assembly (2003-2010) and once led the Bronx Board of Elections. Since leaving office, he has appeared as a commentator on TWC NY1, Bronxnet OPEN, Good Day NY, and Al Jazeera America. His columns and blog focus on corruption, government, education, politics, redistricting, nuclear energy and race. He holds a B.A. in political science from Syracuse University.
All opinions expressed by Editorialists & Columnists on this website and on our videos are solely their own opinions and do not necessarily reflect the opinions of The Bronx Chronicle, its management, or staff. You should not treat any opinion expressed as a specific inducement to make a particular investment or follow a particular strategy, but only as an expression of opinion.
Do you Agree? Disagree? Voice your opinions in the comments!
You may also submit a rebuttal piece to opinions@thebronxchronicle.com. All editorial submissions are subject to proofreading/editing for grammar, structure, and respectability.


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Is there anywhere to hire a car in Le-Havre?
I would also be interested in places to eat in Le Havre Basse Normandie FRANCE.


This afternoon brought my routine check-up with my hygienist and my dentist. Is there a more unappealing job than looking into people's cavities? Well I suppose a gynaecologist comes a close second!
First up was the hygienist. She is an absolute pet....but I still dread her because of the poking and scraping. I was lying back in the chair looking up at the plasma screen on the ceiling,which was obviously there to relax and calm me down.
There was a programme on about the state of the Irish economy, and about how the government is pouring billions of the tax-payers' euro down a black hole and that it will take us about 600 years to claw our way out of it! It would have been less painful if she had stabbed me in the eye with her plaque scraper!
"Can you open your mouth please?"
as every woman's jaw hits her knees when she sees him!
I think he actually had to tell me to close my mouth a little bit, on one particular visit!!!
The examination started. I don't know why dentists haven't perfected the art of asking ,what us teachers know as "closed questions." That is, basically any question that can be answered with a "Yes" grunt or a "No"grunt. Anything that requires a longer answer is a waste of time when you have a mouth full of dental paraphernalia! If you try to answer in a sentence you end up sounding like a cat swimming through a bowl of porridge.
One of the pieces of apparatus that was in my mouth was a little vacuum for sucking up saliva. But in my case, it is strictly for the drool spilling from my mouth as I look up McDreamy's nostrils!
I tried to focus on his conversation which was about his holiday in his villa in Portugal with his (probably impossibly beautiful) family.
Hold on a minute. The one thing I regret is not looking after my teeth properly when I was younger. As a result I have spent the equivalent of the annual budget of a small African nation on rectifying them in the past few years. I bet I've paid for that villa.
Surely that qualifies me for at least a time share in it.....with or without the company of the dentist!!!


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Q: What Postulate States Entropy must be Positive? I've been reading the Postulates of Classical Thermodynamics, and I haven't found anywhere to be said that the Absolute Entropy of a system has to be a positive number.
The third one states that the Temperature, $dU/dS$, must be Positive, since $S$ is monotone increasing with $U$, and that as $U(S)$ approaches flatness, $S$ approaches zero. But this doesn't mean that $S$ can't be negative. Consider for instance the function $U = kS^3$, which is monotone increasing, and where $S$ approaches zero as $dU/dS$ approaches zero from both sides, meaning $S$ could be negative.
Im pretty sure $S$ can't be negative, but I'd like to see the actual proof or Postulate that says so in CLASSICAL (not Statistical) Thermodynamics. Maybe it's included in the definition of entropy and I missed it?

A: In classical physics, the absolute entropy is not well-defined - only entropy differences matter, so shifting your entropy by an overall additive constant doesn't matter.  So entropies can indeed be negative, just as energies can, and that doesn't say anything at all about your system, just about your choice of coordinates.
For example, the microcanonical ensemble for a system with $d$ degrees of freedom is given by $$\Omega(E) = \int \frac{d^dx\, d^dp}{h^d} \delta(H(\{p,x\}) - E) \delta E.$$
In quantum mechanics, $h$ is Planck's constant, but in classical mechanics it can be anything you want - it's just there to get the units right.  So if you decide to make $h$ large enough, then $\Omega(E)$ will become less than 1, and so the entropy $S(E) = k_B \ln \Omega$ will be negative.

A: A better definition of Entropy is given by the statistical mechanics definition of the Gibbs Entropy:
$ S = -k_B \sum{p_i \ln{p_i}}$
Where $S$ is the entropy, $k_B$ is Boltzman's constant and $p_i$ is the probability of the $\mathrm{i^{\mathrm{th}}}$ microstate to be occupied. For any probabilities less than 1, the quantity is clearly always positive. It can be shown that this definition is consistent with the classical thermodynamic entropy

redpajama_set_name: RedPajamaStackExchange


text:
Life and Ministry with J. I. Packer
Download MP3 Message
Life and Ministry with J.I. Packer
J. I. Packer
J. I. Packer is a British-born Christian theologian in the low church Anglican and Reformed traditions.
Mark Dever is the senior pastor of Capitol Hill Baptist Church in Washington, D. C., and the President of 9Marks. You can find him on Twitter at @MarkDever.
By J. I. Packer, Mark Dever
Related Multimedia
By David Helm, Jeremy Meeks, K. Edward Copeland
Numbers 9–11: On Ten Homer Simpsons Worth of Quail Judgment (Bible Talk, Ep. 45)
By Alex Duke, Jim Hamilton, Sam Emadi
By J. I. Packer
By Mark Dever


text:
High School Football Dangers Turns Heads
By ALICE CHEKUNOVA, age 11 Rye High School football player Kyle Ramalho rests and recovers after an injury during a game. PHOTO: Wikimedia Commons More than 1 million U.S. high school students play football. In this season alone, 11 have died. With much media focus on...


The Supreme Court in Indrani Wahi vs. Registrar of Coop. Societies & Ors has held that that transfer of share or interest in a cooperative society, based on a nomination in favour of the nominee, is binding on the said society. Justices J.S. Khehar and C. Nagappan allowed the appeal filed by Indrani Wahi, and directed the society to transfer the share or interest of the society in her favour.
Indrani Wahi had challenged the decisions of the Registrar of Cooperative Societies regarding non-approval of her membership in the Sarobar-View Co-operative Housing Society Limited on the ground that the nomination made by her late father of the petitioner was not in terms of Section 79 of the West Bengal Co-operative Societies Act, 1983 and Rule 127 of the West Bengal Co-operative Societies Rules, 1987. The Single Bench allowed the Writ petition holding that the provisions of the Act did not put any restriction on the major daughters while defining family by recognising and/or referring to their marital status.
However, the Division Bench on Appeal preferred by her mother and brother, held that shares and interest can only be transferred by expressing consent of all the heirs.This order by the Division Bench was assailed before the Apex Court.
Direct the society to transfer the share or interest of the society in favour of the appellant, the Court said that other members of the family is free to pursue his case of succession or inheritance.


Some months ago I wrote about transitioning from a stupid phone to my new smartphone which happens to be the Samsung Note 3. I want to think that this piece of technology is not running my life, and in order to not have "sammie" control me, I came up with some do's and dont's to share with you if you have the addiction.
1. Don't have your phone in your hand every second of the day waiting to comment on Facebook or Twitter as soon as your notification goes off. Better yet, turn off the notifications every so often so you do things without your phone telling you it's time to leave your house, wish someone happy birthday or get to work on time. Did you function before you had your smartphone?
2. Put your phone in your pocket or purse when you are eating at a restaurant. How annoying to share lunch with a friend or have a business lunch while the other person is checking their email or commenting on their instagram. If you find it annoying, then don't do it either.
3. Charge your phone at night in the room furthest away from your bedroom. I have jumped out of bed to answer a wrong number, or worse yet, telemarketers. Whatever pops on your phone can wait for morning.
4. Alternate from texting time and talking time with people. Conversations are better with voice inflections to get the point across. Our young people have great dexterity but no conversational skills. This is not good, especially in a job interview.
5. Don't bring your phone in to the bathroom with you. Cell phones carry more germs than a toilet seat. Enough said about this one.
I am not an anti-techy person, but in my humble opinion people depend too much on their smartphone .Yes, I agree that having a camera at my disposal is a definite asset most of the time, and GPS/Google Maps is a lifesaver. Being able to check email is so convenient, and being able to post on Facebook etc., with pictures, is so unbelievably easy.
But, we should all remember how to use our phone as a phone, which is the second best way to communicate; the first having a face-to-face conversation. Remember those days?


The Operating Room (OR) affects a high percentage of a hospital's revenue. Slight delays in start times, prolonged turnovers, inefficient block utilization and minutes lost searching for missing equipment have serious consequences on efficiency and profitability.
Usable information to report around wait times, room turnaround times, bottlenecks and room utilization.


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text:
Circulating MicroRNAs in Graves' Disease in Relation to Clinical Activity
Izumi Hiratsuka, Hiroya Yamada, Eiji Munetsuna, Shuji Hashimoto, Mitsuyasu Itoh
Department of Hygiene
Background: Understanding the roles of circulating microRNAs (miRNAs) can provide important and novel information regarding disease pathogenesis and a patient's clinical condition. Circulating miRNAs, such as exosomal miRNA, may regulate various bioactivities related to intercellular communication. However, the circulation of miRNAs in Graves' disease (GD) in relation to disease activity has never been elucidated. This study aimed to identify circulating miRNAs in GD in relation to disease activity and whether their exosomes play a role in the pathogenesis of GD. Methods: Circulating miRNAs were measured in serum obtained from seven intractable GD patients, seven GD patients in remission, and seven healthy controls using the miScript miRNA PCR Array. Altered miRNAs selected from array data were validated in 65 subjects. To investigate exosome biology, peripheral blood mononuclear cells (PBMCs) were incubated with exosomes isolated from the subjects' sera. mRNAs were quantified for cytokines using quantitative real-time polymerase chain reaction. Results: Circulating miR-23b-5p and miR-92a-39 were increased in GD patients in remission compared with intractable GD patients (p < 0.05). On the other hand, let-7g-3p and miR-339-5p were decreased in GD patients in remission compared with intractable GD patients (p < 0.05). Exosomes from intractable GD patients stimulated mRNA expression for IL-1β and TNF-α compared with GD patients in remission or healthy controls. Conclusions: This study demonstrates that different levels of circulating miRNAs are associated with intractable GD. Moreover, serum exosomes of patients with intractable GD may activate immune cells, which may play an important role in GD pathogenesis.
https://doi.org/10.1089/thy.2016.0062
Hiratsuka, I., Yamada, H., Munetsuna, E., Hashimoto, S., & Itoh, M. (2016). Circulating MicroRNAs in Graves' Disease in Relation to Clinical Activity. Thyroid, 26(10), 1431-1440. https://doi.org/10.1089/thy.2016.0062
Hiratsuka, Izumi ; Yamada, Hiroya ; Munetsuna, Eiji ; Hashimoto, Shuji ; Itoh, Mitsuyasu. / Circulating MicroRNAs in Graves' Disease in Relation to Clinical Activity. In: Thyroid. 2016 ; Vol. 26, No. 10. pp. 1431-1440.
@article{44999b84f72840b7a3f999f8d80e032c,
title = "Circulating MicroRNAs in Graves' Disease in Relation to Clinical Activity",
abstract = "Background: Understanding the roles of circulating microRNAs (miRNAs) can provide important and novel information regarding disease pathogenesis and a patient's clinical condition. Circulating miRNAs, such as exosomal miRNA, may regulate various bioactivities related to intercellular communication. However, the circulation of miRNAs in Graves' disease (GD) in relation to disease activity has never been elucidated. This study aimed to identify circulating miRNAs in GD in relation to disease activity and whether their exosomes play a role in the pathogenesis of GD. Methods: Circulating miRNAs were measured in serum obtained from seven intractable GD patients, seven GD patients in remission, and seven healthy controls using the miScript miRNA PCR Array. Altered miRNAs selected from array data were validated in 65 subjects. To investigate exosome biology, peripheral blood mononuclear cells (PBMCs) were incubated with exosomes isolated from the subjects' sera. mRNAs were quantified for cytokines using quantitative real-time polymerase chain reaction. Results: Circulating miR-23b-5p and miR-92a-39 were increased in GD patients in remission compared with intractable GD patients (p < 0.05). On the other hand, let-7g-3p and miR-339-5p were decreased in GD patients in remission compared with intractable GD patients (p < 0.05). Exosomes from intractable GD patients stimulated mRNA expression for IL-1β and TNF-α compared with GD patients in remission or healthy controls. Conclusions: This study demonstrates that different levels of circulating miRNAs are associated with intractable GD. Moreover, serum exosomes of patients with intractable GD may activate immune cells, which may play an important role in GD pathogenesis.",
author = "Izumi Hiratsuka and Hiroya Yamada and Eiji Munetsuna and Shuji Hashimoto and Mitsuyasu Itoh",
doi = "10.1089/thy.2016.0062",
journal = "Thyroid",
Hiratsuka, I, Yamada, H, Munetsuna, E, Hashimoto, S & Itoh, M 2016, 'Circulating MicroRNAs in Graves' Disease in Relation to Clinical Activity', Thyroid, vol. 26, no. 10, pp. 1431-1440. https://doi.org/10.1089/thy.2016.0062
Circulating MicroRNAs in Graves' Disease in Relation to Clinical Activity. / Hiratsuka, Izumi; Yamada, Hiroya; Munetsuna, Eiji; Hashimoto, Shuji; Itoh, Mitsuyasu.
In: Thyroid, Vol. 26, No. 10, 01.10.2016, p. 1431-1440.
T1 - Circulating MicroRNAs in Graves' Disease in Relation to Clinical Activity
AU - Hiratsuka, Izumi
AU - Yamada, Hiroya
AU - Munetsuna, Eiji
AU - Hashimoto, Shuji
AU - Itoh, Mitsuyasu
N2 - Background: Understanding the roles of circulating microRNAs (miRNAs) can provide important and novel information regarding disease pathogenesis and a patient's clinical condition. Circulating miRNAs, such as exosomal miRNA, may regulate various bioactivities related to intercellular communication. However, the circulation of miRNAs in Graves' disease (GD) in relation to disease activity has never been elucidated. This study aimed to identify circulating miRNAs in GD in relation to disease activity and whether their exosomes play a role in the pathogenesis of GD. Methods: Circulating miRNAs were measured in serum obtained from seven intractable GD patients, seven GD patients in remission, and seven healthy controls using the miScript miRNA PCR Array. Altered miRNAs selected from array data were validated in 65 subjects. To investigate exosome biology, peripheral blood mononuclear cells (PBMCs) were incubated with exosomes isolated from the subjects' sera. mRNAs were quantified for cytokines using quantitative real-time polymerase chain reaction. Results: Circulating miR-23b-5p and miR-92a-39 were increased in GD patients in remission compared with intractable GD patients (p < 0.05). On the other hand, let-7g-3p and miR-339-5p were decreased in GD patients in remission compared with intractable GD patients (p < 0.05). Exosomes from intractable GD patients stimulated mRNA expression for IL-1β and TNF-α compared with GD patients in remission or healthy controls. Conclusions: This study demonstrates that different levels of circulating miRNAs are associated with intractable GD. Moreover, serum exosomes of patients with intractable GD may activate immune cells, which may play an important role in GD pathogenesis.
AB - Background: Understanding the roles of circulating microRNAs (miRNAs) can provide important and novel information regarding disease pathogenesis and a patient's clinical condition. Circulating miRNAs, such as exosomal miRNA, may regulate various bioactivities related to intercellular communication. However, the circulation of miRNAs in Graves' disease (GD) in relation to disease activity has never been elucidated. This study aimed to identify circulating miRNAs in GD in relation to disease activity and whether their exosomes play a role in the pathogenesis of GD. Methods: Circulating miRNAs were measured in serum obtained from seven intractable GD patients, seven GD patients in remission, and seven healthy controls using the miScript miRNA PCR Array. Altered miRNAs selected from array data were validated in 65 subjects. To investigate exosome biology, peripheral blood mononuclear cells (PBMCs) were incubated with exosomes isolated from the subjects' sera. mRNAs were quantified for cytokines using quantitative real-time polymerase chain reaction. Results: Circulating miR-23b-5p and miR-92a-39 were increased in GD patients in remission compared with intractable GD patients (p < 0.05). On the other hand, let-7g-3p and miR-339-5p were decreased in GD patients in remission compared with intractable GD patients (p < 0.05). Exosomes from intractable GD patients stimulated mRNA expression for IL-1β and TNF-α compared with GD patients in remission or healthy controls. Conclusions: This study demonstrates that different levels of circulating miRNAs are associated with intractable GD. Moreover, serum exosomes of patients with intractable GD may activate immune cells, which may play an important role in GD pathogenesis.
U2 - 10.1089/thy.2016.0062
DO - 10.1089/thy.2016.0062
JO - Thyroid
JF - Thyroid
Hiratsuka I, Yamada H, Munetsuna E, Hashimoto S, Itoh M. Circulating MicroRNAs in Graves' Disease in Relation to Clinical Activity. Thyroid. 2016 Oct 1;26(10):1431-1440. https://doi.org/10.1089/thy.2016.0062
10.1089/thy.2016.0062


It has been 45 days since the EFF called up the selected youth national team athletes following the local pre-competition championships. The EAF has selected 14 senior and new coaches for various events. The Ethiopian athletics governing body has unveiled that the field event will open an opportunity to develop experiences through the championships, mainly focusing on jumping and throwing events.
The team will also participate in various track events starting from 100m to 10k races. However, only the male athletes will represent in distances of 5,000m, 10,000m whereas the women participate in 3,000m and 5,000m distance races. The championship also includes steeplechase races in 2,000m distance.
Abidjan has been selected as the host of the CAA African U18 (youth) and U20 (junior) athletics championships in April. It is the third African U-18 Championships and the 14th African championships.