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Antifungals ›
Levothroid (Levothyroxine)
Levothroid is used to treat hypothyroidism (low thyroid hormone). Levothroid is given when your thyroid does not produce enough of this hormone on its own. Levothroid is also used to treat or prevent goiter (enlarged thyroid gland), which can be caused by hormone imbalances, radiation treatment, surgery, or cancer.
Eltroxin, Levothyroxine, Levoxyl, Roxin, Synox, Synthroid, Thyronorm, Thyrosec, Thyrowin, Thyrox, Unithroid
Glucophage, Xeloda, Ovral, Adipex, Starlix, Nizoral
Also known as: Levothyroxine
Levothyroxine injection is used to treat myxedema coma (severe hypothyroidism), a condition where the thyroid gland does not produce enough thyroid hormone. The powder form of levothyroxine injection can be used as a substitute for the oral dose when a rapid effect is needed and when the oral route is not allowed.
This medicine is to be given only by or under the supervision of your doctor.
This product is available in the following dosage forms:
Powder for Solution
This section provides information on the proper use of a number of products that contain levothyroxine. It may not be specific to Levothroid. Please read with care.
This medicine will need to be taken for the rest of your life or your child's life. Do not stop taking this medicine or change your dose without first checking with your doctor. It may take several weeks before you start to notice that your symptoms are better.
It is best to take this medicine on an empty stomach. Take it with a full glass of water at least 30 minutes to 1 hour before eating breakfast.
Swallow the capsule whole. Do not cut or crush it. Also, if you are taking multiple strengths of this medicine, remove the capsules from the blisters in advance to help you identify the strength of each capsule.
For infants and children who cannot swallow the tablet form, the tablet can be crushed and mixed with a small amount of water (5 to 10 milliliters [mL] or 1 to 2 teaspoonfuls). You may use a spoon or dropper to give the mixture. Use the mixture right away and do not store it to use later.
If you are using the oral liquid:
This medicine should come with patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions. This medicine may be mixed with water or be given directly into the mouth. If mixed with water, squeeze the contents of 1 single unit-dose ampule into a glass or cup containing water. Stir and drink it immediately. Add some water to the glass or cup and drink the water. This will help get all of the medicine out of the glass or cup. Do not mix this medicine with any other liquid except water. Do not store the mixture for later use. If taken without water, squeeze the medicine directly into the mouth or into a spoon and swallow it immediately.
This medicine should be taken at least 4 hours before or 4 hours after these medicines: antacids (Maalox®, Mylanta®, Tums®), calcium supplements, stomach medicines (including lansoprazole, omeprazole, pantoprazole, Aciphex®, Dexilant®, Nexium®, Prevacid®, Prilosec®), cholestyramine (Prevalite®, Questran®), colesevelam (Welchol®), colestipol (Colestid®), iron supplements, Kayexalate®, orlistat (Alli®, Xenical®), simethicone (Gas-X®, Mylicon®), and sucralfate (Carafate®).
Cotton seed meal, dietary fiber, soybean flour (infant formula), or walnuts may affect the absorption of this medicine from your body. You may have to take this medicine at a different time of day from when you eat these foods. Talk with your doctor more about this if you have concerns.
Do not eat grapefruit or drink grapefruit juice while you are using this medicine.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
For oral dosage form (capsules): For hypothyroidism: Adults and children older than 12 years of age (growth and puberty complete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 1.7 microgram (mcg) per kilogram (kg) of body weight per day but may be less in older adults. Children older than 12 years of age (growth and puberty incomplete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 2 to 3 mcg per kg of body weight per day. Children 6 to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 4 to 5 mcg per kg of body weight per day. Children younger than 6 years of age—Use is not recommended as your child might not be able to swallow the capsules. For thyroid cancer: Adults—Dose is based on body weight and must be determined by your doctor. The dose is usually more than 2 microgram (mcg) per kilogram (kg) of body weight per day. Children—Use and dose must be determined by your doctor. For oral dosage form (solution): For hypothyroidism: Adults and children older than 12 years of age (growth and puberty complete)—Dose is based on body weight and must be determined by your doctor. The starting dose is usually 1.7 microgram (mcg) per kilogram (kg) of body weight per day. Your doctor may adjust your dose as needed. Children older than 12 years of age (growth and puberty incomplete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 2 to 3 mcg per kg of body weight per day. Children 6 to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 4 to 5 mcg per kg of body weight per day. Children 1 to 5 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 to 6 mcg per kg of body weight per day. Children 6 to 12 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 6 to 8 mcg per kg of body weight per day. Children 3 to 6 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 8 to 10 mcg per kg of body weight per day. Children 0 to 3 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 10 to 15 mcg per kg of body weight per day. For thyroid cancer: Adults—Dose is based on body weight and must be determined by your doctor. The dose is usually more than 2 microgram (mcg) per kilogram (kg) of body weight per day. Children—Use and dose must be determined by your doctor. For oral dosage form (tablet): For hypothyroidism: Adults and children older than 12 years of age (growth and puberty complete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 1.6 microgram (mcg) per kilogram (kg) of body weight per day but may be less in older adults. Children older than 12 years of age (growth and puberty incomplete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 2 to 3 mcg per kg of body weight per day. Children 6 to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 4 to 5 mcg per kg of body weight per day. Children 1 to 5 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 to 6 mcg per kg of body weight per day. Children 6 to 12 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 6 to 8 mcg per kg of body weight per day. Children 3 to 6 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 8 to 10 mcg per kg of body weight per day. Children 0 to 3 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 10 to 15 mcg per kg of body weight per day.
If you overdose Generic Levothroid and you don't feel good you should visit your doctor or health care provider immediately.
Use the oral liquid within 15 days after opening the pouch. Keep the ampules in the pouch until you are ready to use them.
The most common side effects associated with Levothroid are:
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Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Actions of two dopamine derivatives at adreno- and cholinoceptors. Hepatic glucuronly transferase activity was increased threefold during Phase II and during the remainder of the neonatal period. Interchangeabilities of activator lights in polymerization of visible light-cured composite resin. Use of sinusoid modulated currents in the treatment of women with stress-induced urinary incontinence. Gentle handling for 1 min also significantly increased plasma levels of DOPA, NE, EPI, and the NE metabolites DHPG and MHPG, without increasing levels of DA or HVA. Ultraviolet light may contribute to geographic and racial blood pressure differences. Incomplete coincidence of histochemical changes following hypophysectomy with the changes caused by the action of cortisone for the same period (10 days), and also a distinct depression with cortisone of histochemical shifts characteristic of the action of ACTH in hypophysectomized animals pointed to the direct (not mediated through the hypophysis) influence of cortisone on the adrenal cortex. Assay of the laminin P1 using a radioimmunologic technic: applications in oncology. Study by ribosomal DNA ITS 2 sequencing and RAPD analysis on the systematics of four Metastrongylus species (Nematoda:Metastrongyloidea).
The highest overall rates of responding were maintained under the fixed-ratio schedule and under the fixed-ratio component of the multiple schedule. The present findings suggest that moist bonding is required for optimum infiltration of adhesive resin into the demineralized layer. From these results it is concluded that procaine and lidocaine inhibited excision-repair process in UV-irradiated E. Studies on psychomotoric effects and pharmacokinetic interactions of the new calcium sensitizing drug levosimendan and ethanol. Computer-assisted interpretive reporting with trend analysis of creatine kinase and lactate dehydrogenase isoenzyme determinations.
The membrane serves as an interface across which liquid-liquid extraction takes place. Staphylococcus intermedius-specific IgA cross reacted with Staphylococcus aureus but not with Gram negative bacteria. The detection and characterization of soluble immune complexes is complicated by the broad spectrum of complexes occurring in human pathology. In the present study, we analyzed whether impaired myelination of retinal ganglion cell axons is detectable in adult MAG mutants. The first R406W brain showed many NFT in affected regions with only a few diffuse amyloid plaques. Results for several liquids and solutions such as water, methanol, various saline solutions, and solutions of DNA and DNA sodium salt in water are described.
At lower shear rates, increased red cell aggregation, primarily mediated by elevated fibrinogen concentration, accounted for the higher blood viscosity in the hypertensive subjects. Cyclooxygenase (COX) is an intracellular enzyme that converts arachidonic acid into prostaglandin (PG)G2 and PGH2. Taken together, these results suggest that biologic activities of HIV-1 Tat in human monocytes may, at least in part, be elicited by activation of VEGFR-1/Flt-1. Further improvements in the survival of patients with cholangiocarcinoma will come with the early diagnosis of these lesions. Prevalence of susceptibility to quinolones and other antibiotics in microorganisms isolated from community bacteriuria in Madrid in 1995. Restriction analysis of influenza-specific cloned cell lines issued from an HLA-DRw6/DR- donor. There was no pathologic evidence of canine distemper in that panda. Interplay of group and family treatment techniques in multifamily group therapy.
The importance of the virulence of the strains used for the preparation of vaccines, as well as the method of their preparation, for the immunogenic potency of vaccines is shown. The metabolic significance of reduced serum B 12 in folate deficiency. Sleep-related oxygen desaturation and daytime pulmonary haemodynamics in COPD patients. To investigate the role of FasL in the apoptosis of lymphocytes in autoimmune diseases, gene and protein expression of FasL were examined in peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA), and from healthy donors by a newly-designed semiquantitative reverse transcription (RT)-PCR and flow cytometry. Clinical course and outcome of primary acute angle-closure glaucoma in Singapore. The newly formed follicles can either incorporate into the existing gland, or form independent follicles. Comparison of total urinary coproporphyrin excretion in lead poisoning with other pathological conditions.
frequency-dependent, incrementing facilitation at higher presynaptic frequencies. The labiolingual diameters of the root canal in the apical constriction of the central incisors, the lateral incisors and the cuspids were 0.425 mm, 0.369 mm and 0.425 mm respectively. Then, the sample is cryo-transferred to an SEM equipped with a cold stage and imaged with the material-dependent backscattered electron signal that shows the platinum distribution. Degenerating cells often contained membrane-bound granules and clusters. The lasting sharpness of the diamond blade results in a far cleaner, less traumatic, cutting edge as can be demonstrated by scanning electron micrographs of incised coronary walls after the use of various types of coronary knives and scissors. The sequence of palF, an environmental pH response gene in Aspergillus nidulans. In cases of patients with late overcorrection, proptosis and superior rectus muscle volume, as measured preoperatively, were significantly greater than in the stable comparison group. Our observations link bulimia nervosa to altered 5-HT functioning, and suggest that there may be a relatively symptom-specific association between impulsivity and reduced 5-HT reuptake. This fluorocarbon surfactant produces aggregates which are long ( approximately 100 nm) and thin ( approximately 5 nm), and about one molecule ( approximately 1.3 nm) deep. Sequence analysis of the gene coding for glyceraldehyde-3-phosphate dehydrogenase (gpd) of Podospora anserina: use of homologous regulatory sequences to improve transformation efficiency.
The action of LAF differs from those of cGMP itself by being non-dialysable, and unable to prevent the inhibitory action of cAMP on mitogen-stimulated lymphocyte proliferation. A 57-year-old woman with progressive disturbance of gait and mental deterioration. Preparation of islets of Langerhans from rabbits and hamsters by the collagenase digestion technique. Toxicological correlation between changes in blood biochemical parameters and liver histopathological findings. Experimental production and study of complex native and purified sera against rabies and tetanus. Preparation of p-dimethylaminoazobenzene containing isotopic nitrogen. Localization of the genes coding for GTP cyclohydrolase II and riboflavin synthase on the chromosome of Escherichia coli K-12. Active immunization has received a new impulse most recently through the treatment of tumor cells with the enzyme neuraminidase from Vibrio cholerae. The left ventricular ejection fraction could be regarded as independent of the determinants studied.
Therefore, CPT albumin microsphere is a peripheral type of biodegradable embolizing agent. Western blots further demonstrated that alpha-lipoic acid inhibited the release and translocation of NF-kappaB from the cytoplasm into the nucleus. These are considered to be thymic hormones, which physiologically induce the differentation of prothymocytes to thymocytes within the thymus. With use of wild-type and IL-10-deficient mice, the aim of the current investigation was to determine whether IL-12 is produced in myocardial reperfusion injury and whether endogenous IL-10 modulates its production. The purpose of this presentation is to present our nonincision technique to create aesthetically pleasing supratarsal folds. This pattern of relations was obtained after controlling for prior transgressiveness. The specimens were ground wet and polished to a thickness of 0.21 mm for the examination of the interface with a light microscope.
Tyrosine phosphorylation of the insulin receptor and IRS-1 was increased by insulin. Drug ion-selective electrodes made with hetero-poly anion as exchange site exhibit better performances than the respective electrodes of conventional tetraphenylboron type, yielding low detection limits and fast responses. In this context no antibody used alone is reliable for corroborating a diagnosis, but the selective use of a small panel of three markers (CEA, Ber-EP4 and LeuM1) can be very useful in solving diagnostic difficulties in the cytodiagnosis of serous effusions. For the surgical treatment of hemorrhoids, the Whitehead-operation is considered bad because it leads to complications like anal stenosis, incontinence and mucous ectropion or prolapsus. Streptomycin as an adjunct in surgical treatment of pulmonary tuberculosis. Pattern of incoming calls to an emergency medical service station in a rural region. Experiences with use of the x-ray image intensifier in gynecology and obstetrics. Thus, these results suggest that there are at least two distinct pathways for intronless mRNA expression, one related to and the other unrelated to Rev and Rex functions.
The hybridization signature of complex cDNA probes prepared from total RNA extracted from immature and mature DC were analyzed using a mouse thymic cDNA library, gridded on high density filters. Many sera also had elevated levels of antibodies specific for RBC antigens. Cattle with microorganisms that degraded 2,3-DHP were mostly Senepol cattle imported from St. The last two enzymes of the pathway, argininosuccinate synthetase and argininosuccinate lyase, were previously shown to be cytosolic. The pathogenic role of several factors in the context of adult-onset patients, but also in regards to studies already performed in juvenile-onset patients, is discussed. The bones commonly fractured when the foal galloped to exhaustion trying to keep up with its dam in the paddock. Ultrastructure of the nuclear apparatus of the infusorian Loxodes magnus. Controlled limb reperfusion was performed in two patients who were admitted for lower limb-threatening ischemia as a result of embolism. We show here that NBP binds to a 22-bp sequence containing an imperfect inverted repeat in the promoter-proximal NRE.
Genetic control of spermiogenesis in Drosophila melanogaster: the effects of abnormal association of centrosome and nucleus in mutant ms(1)6S. Lead exposure also elevated brain norepinephrine, homovanillic acid, and 5-hydroxyindole acetic acid (5-HIAA) levels and concentration of lead in blood and tissue. The cuticle is a major barrier prohibiting the infection of nematodes against micro-organisms. After this procedure, during recovery sleep, the latency of onset of the first rhombencephalic - paradoxical sleep period decreased and the proportion of telencephalic/rhombencephalic - slow wave sleep reversed (during the first hour of recovery sleep). Treatments targeted at each of these mechanisms can be used as appropriate. Chimeric plasmids containing the uvsY uvsW region of the T4 genome were examined for the expression of these genes. Separate substitutions of sodium, chloride of bicarbonate did not significantly alter the SLS-caused absorption, except that the substitution of choline for sodium reduced the absorption of pralidoxime, both in the presence and in the absence of SLS. The clinical circumstances and radiographic features of these cases are described, and the existing literature pertaining to this phenomenon is reviewed. The lag glucose tolerance also becomes indistinguishable from normal.
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Women with PCOD were at increased risk of gestational diabetes and pregnancy-induced hypertension, and this risk appeared to be independent of body mass index. The resulting metabolic conversion products interact with putative steroid receptors within bactrim dosage mg the cells, and through those interactions, they may exert either agonistic, synergistic and antagonistic hormonal effects. Additional studies are needed to determine whether these techniques reduce the incidence of perioperative ischemic complications. Because of the difficulty in distinguishing the types of male pseudohermaphroditism microscopically, we recommend that XY female children should undergo thorough endocrinologic investigation before orchidectomy. Therefore, health care workers dealing with this disease must maintain an open mind about what constitutes optimal therapy. Corticosteroid therapy of diabetics with special reference to intra-articular administration. The other group received the same medication with the addition of rifampin in the last 5 days. Inhibition of urease activity also reduced total statoconia number, but had no effect on statoconia volume.
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Fatal cardiac insufficiency in the course of an dilantin overdose side effects initial acute myocardial infarct. Mutagenicity of the enantiomers of the diastereomeric bay-region benz(a)anthracene 3,4-diol-1,2-epoxides in bacterial and mammalian cells. Enlargement of the bronchial arteries, and their anastomoses with the pulmonary arteries in bronchiectasis. A lung model was constructed using a 5 L anesthesia bag connected to a mechanical ventilator with a heated humidifier. Treatment of advanced malignant melanoma with high-dose melphalan and autologous bone marrow transplantation. Radioimmunoassay has been used for time in the detection of the Australia Antigen. Several studies have already shown that long-term CyA administration results in a decrease in CLi reflecting enhanced lithium ion reabsorption.
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Recent studies suggest that dlk is a negative regulator of adipocyte differentiation, a promoting factor of cobblestone area colony formation, and a molecule which influences stromal cell-pre-B cell interactions and augments cellularity of developing thymocytes. Almost every clinical laboratory, regardless of physical location, comes under the daily influence of a plethora of federal bureaus and administrations, state agencies, and local government entities. Net hepatic release of glucose was increased at nearly all samplings, but de-B12 ewes had a greater increment of total hepatic influx and efflux. The purpose of this study was to test the hypothesis that computer games may be an efficient therapeutic tool in a cognitive rehabilitation program. Applicability of culture medium containing acriflavine for the isolation of Listeria monocytogenes. It was concluded that stress and diets high in certain types of fatty acids depress the immune response in rats, possibly via a mechanism which has some common pathways. These promising cost effective group treatments remain to be tested in a controlled trial.
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FAK is cleaved by the ordered proteolytic activity of 2 different members of the caspase-3 family. Lithium intoxication occurring with the use of a table salt substitute in the low sodium dietary treatment of hypertension and congestive heart failure. Nasal fistula associated with dental infection: a report of a case. These numerous, uniform, and spherical structures are approximately 10 micrometers in diameter when formed, and are positive to stains specific for proteins and nucleic acids. However, in Synechococcus 6301 strain GR6, a cyanobacterium that is resistant to 100 microM gabaculine, this enzyme has undergone two changes in structure: a deletion of three amino acids from positions 5 to 7 and the substitution of isoleucine for methionine at position 248. Preliminary results from a prospective randomized clinical trial indicate that radical mastectomy and primary radiation therapy result in equivalent survival rates.
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The obtained relations are compared with other recently proposed systematics based on the statistical model as well as on the asymmetry parameter dependence. Therefore average shift dust levels increase and considerably exceed the MAC. We report the case of a 62-year-old man who was administered sodium valproate (VPA) and who subsequently developed the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). An electrochemical evidence of free radicals formation from flutamide and its reactivity with endo/xenobiotics of pharmacological relevance. amiloride drug classification Hemodynamic changes in response to rationed exercise are the most demonstrative.
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A heterodimer of the Zn2Cys6 transcription factors Pip2p and Oaf1p controls induction of genes encoding peroxisomal proteins in Saccharomyces cerevisiae. Infections of mammalian malaria parasites start when sporozoites from an infected anopheline mosquito are injected into the bloodstream of the host. Patients rated their level of pain immediately after surgery and at regular intervals for 3 days after surgery using the Wong-Baker Faces Pain Rating Scale (1-6). Respiratory, muscular, and overall perceptions of effort: the influence of hypoxia and muscle mass. The effects of endotoxemia and fluid expansion on gastric hemodynamics and mucosal permeability in the baboon. Induction of liver lysosomal enzymes during the autophagic phase following phenobarbital treatment of rat. A repeat examination of the skeletal muscle shows that the previous ultrastructural changes in the muscles are related to the growth hormone levels. At autopsy, the right pleural cavity was obliterated by the tumor mass which covered the collapsed pulmonary parenchyma and was clearly demarcated from it.
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Induction of lens fibre differentiation by acidic and basic bisoprolol zebeta dosage fibroblast growth factor (FGF). The inoculation of a xenobiotic in one of the compartments of the fertilized egg is the usual technique used in these studies. Characteristics of thyrotropin binding and solubilization of thyrotropin receptor activity by tryptic digestion. Aging and the visceral musculature of the adult fruitfly: an ultrastructural investigation. This has been in response to changes in society, technology and medicine. Derivation of mouse sarcoma virus (Kirsten) by acquisition of genes from heterologous host. In certain cases the participation of craniofacial surgeon is likewise needed. The combined study of the 3 tests proved to be useful when the blink reflex showed an isolated R1 delay, that is, in cases in which the level of damage along the trigemino-facial reflex arc cannot be defined by the recording of the blink reflex alone. carinii cysts and trophozoites were isolated from immunosuppressed rats, lysed in situ in agarose blocks, and subjected to orthogonal-field gel electrophoresis (OFAGE) and contour-clamped homogeneous-field gel electrophoresis (CHEF).
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Hyaluronidase-induced inhibition of the insulinotropic action of sulfonylureas, leucine, and glucagon in rodent isolated pancreatic islets. These schedules were selected because 5-FUdR pretreatment had been shown to sensitize L5178Y cells in culture to acute cell death by ara-C. Bacteriological studies in a patient with antibiotic-associated pseudomembranous colitis. India ink introduced into the portal circulation filled all liver vessels but was systematically excluded from even the earlier amebic lesions. A simple modification to the conventional operative technique, involving the incorporation of a vein patch into the distal anastomosis, has enabled considerable improvement. The strains proved to be different from mycoplasma species isolated from geese before. Data from comprehension tasks raise the possibility that production factors were responsible for some of the differences seen. A case with penicillinase producing Neisseria gonorrhoeae in Denmark. Antegrade selective cerebral perfusion with cold blood during aortic arch surgery.
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Radioimmunoassay of plasma prolactin and specific receptors, together with epidemiological enquiries, should rapidly albendazole 200 mg price confirm or refute the cocarcinogenic effect of prolactin. The patients were non-immune travellers infected in East Africa and in the neighbouring islands, especially Tanzania, Kenya and Madagascar. A patient with choreoathetosis and dystonia who had computerized tomography evidence of basal ganglia damage resulting from tuberculous meningitis is presented. Patients were scheduled by tumour stage and medical condition into a curative group (21 patients) and into a palliative group (33 patients). These results show that different mineral deficiencies have different effects on NaCl intake. The acid--immiscible with lecithin--forms well defined pure acid domains in the monolayer. A second cytochrome, cytochrome beta561, seems to be reducible by hydrosulfite only.
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When M1 was mixed with lysates of uninfected cells there was selective binding of histones H2A, H2B, H3, and H4. Improvement of peripheral circulation by vitamin E and the objective control of its effect with the aid of norvasc medication and grapefruit the Szirmai neo-or myograph and myotonometer. Temperature compensation of sodium transport and ATPase activity in frog skin. Another study was performed on 25-day-old male rats to determine the effects of intraventricular administration of melatonin (MEL) alone, and intraventricular MEL plus i.p. Protein insufficiency enhances cell-mediated immunity while depressing or not affecting humoral immunity. Major vaccination efforts will raise the average age of measles attack, but the peak incidence will remain in the first year of life. Patterns of serum cortisol levels in ovariectomized females with and without androgen administration. Neither the integrin pattern nor the biological functions of integrins have been extensively documented in human cultured testicular peritubular myoid cells (TPMC). techniques, such as the formed in the highly specialized center of Bancaud and Talairach, open new perspectives particularly for the cases resistant to medical treatment and without evidence of focalisation. Conscience and cannibals: an essay on two exemplary tales--Soul of Wood and The Pawnbroker.
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Within the context of increasing numbers of operations aimed to preserve the mitral valve, the importance and difficulty of prompt recognition and adequate treatment of this very uncommon but potential lethal complication are emphasised. Finally, the following membrane disorders were examined based on lipid peroxidation. Twenty-eight patients with oat cell carcinoma of the lung were treated with cyclophosphamide, vincristine, procarbazine, and prednisone with and without irradiation. The clinical significance of the results suggest that software-assisted remediation may not be an appropriate modality for achievement of a functional occupational therapy outcome. Respiratory system efficiency and breathing regulation of persons classified to the methadone maintenance treatment.


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Q: Is there a way to find a statistical distribution for the below data? Is there a way to find a statistical distribution for the below data?
This is derived from frequency count of different topics in a large corpus of news stories. I wonder if this follows a Poisson Distribution or some other distribution or "none at all".
As an example n=2 and Count=22939 means that there are 22939 different topics that appear exactly twice in a corpus of news stories. The last non-zero value n=687 and Count=1 means that there is 1 topic that appears in 687 news stories.
n   Count
1   115323
2   22939
3   6538
4   4841
5   2193
6   1682
7   928
8   909
9   608
10  654
11  422
12  417
13  286
14  313
15  179
16  189
17  108
18  133
19  72
20  113
21  65
22  99
23  43
24  66
25  40
26  58
27  27
28  51
29  32
30  50
31  27
32  30
33  20
34  23
35  13
36  28
37  16
38  19
39  6
40  20
41  13
42  21
43  10
44  16
45  12
46  10
47  14
48  18
49  7
50  8
51  5
52  10
53  6
54  11
55  5
56  8
57  9
58  11
59  3
60  12
61  4
62  3
63  6
64  8
65  5
66  3
67  3
68  11
69  3
70  3
71  6
72  8
73  1
74  2
75  5
76  5
77  3
78  2
79  1
80  0
81  1
82  6
83  2
84  5
85  4
86  2
87  3
88  2
89  2
90  4
91  0
92  0
93  4
94  3
95  2
96  2
97  3
98  2
99  0
100 3
101 2
102 0
103 1
104 0
105 1
106 0
107 2
108 2
109 2
110 1
111 0
112 0
113 0
114 0
115 1
116 1
117 0
118 2
119 2
120 0
121 0
122 0
123 2
124 2
125 1
126 1
127 0
128 1
129 0
130 1
131 1
132 1
133 0
134 1
135 0
136 0
137 0
138 0
139 0
140 1
141 0
142 1
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Category: community
Action Needed: Save the Historic Tax Credit
November 8, 2017 November 7, 2017 3 Comments
Do you know how your state is affected by the Historic Tax Credit (HTC)? Do you know that a lot of downtown and village revitalization would not happen without the aid of the HTC? The HTC makes up the difference in project cost, which allows for the buildings to be rehabilitated.
Need an example? A current project in Enosburg Falls, Vermont is rehabilitating the historic Quincy Hotel. This building, constructed in 1874, began as a railroad hotel and served travelers well into the 21st century, becoming one of the longest continually operating hotels in Vermont.
Quincy House, ca. 1910, prior to the fire on the 3rd floor, which resulted in the altered windows and roof (see next photo). Image source: Enosburg Historical Society.
Image source: https://www.cardcow.com/461985/street-view-quincy-house-enosburg-falls-vermont/
Enosburg Falls is a typical example of a northern Vermont village; it was a bustling village and regional hub for industry, but with the demise of the railroad, it entered a protracted period of economic decline. This was manifested in a village center with many underutilized buildings and consequently fewer options for local employment, which have adversely affected the cohesiveness and vibrancy of the community. People left, businesses left, and buildings fell into disrepair. On top of that, the village suffered fires in some of its main building blocks.
One of the rooms inside the Quincy Hotel prior to rehabilitation.
The rehabilitation of Quincy Hotel will provide the community with public spaces to host events ranging from business meetings to workshops and retreats, all with in -house accommodations and meals, complementing what is already in the Village. The hotel is located downtown and adjacent to the Enosburg Opera House. The railroad has been converted to the Missisquoi Valley Rail Trail; cyclists and tourists will find comfortable lodging at the Quincy Hotel. The rehabilitation of the Quincy Hotel would not be economically feasible without the state and federal Historic Tax Credits. There is a need for this project; Enosburg Falls is undergoing revitalization by dedicated residents and business people with investment in restaurants, retail, housing, parks, and now lodging. Long-time readers will recall the Flying Disc coffee shop, a locally owned and successful coffee shop, which is just a short walk from the Quincy Hotel.
This project, like all tax credit projects, will act as an economic multiplier; a catalyst for continued economic development. The local tax base will expand and jobs will be created as a direct result of this project. Even one small project can serve as a catalyst, leading to larger projects. Bringing housing downtown encourages commercial development (restaurants, retail, office spaces) and investment in a town or city block. This makes our existing communities more livable for all, and prevents poor development (i.e. sprawl) elsewhere. People want to live and work in vibrant communities.
So far tax credit projects seem like win-win situations, right? Yes. However, over the years our preservation efforts – from ordinances to regulations to tax credits – have been threatened at the local, state, and national levels. The only way to prevent their loss is to speak up! Right now is one of those times. Read on for an overview of the issues and how to help save the Historic Tax Credit (HTC), formerly called the Rehabilitation Investment Tax Credit (RITC).
The issue: The current tax reform bill introduced in the House of Representatives would eliminate the HTC. The HTC is a proven economic driver, as well the federal government's most significant investment in historic preservation. If we take away the HTC, businesses and development projects are far less likely to pursue preservation projects because there will be no financial incentive. Why invest additional money if there will not be a guaranteed return-on-investment for developers?
Does this matter? Yes, it matters. If you take away the HTC, you take away valuable preservation dollars and in turn, irreplaceable historic fabric of your communities. How much of an impact will it have in your city or state? Find your state here and download an easy to use fact sheet. You can see which projects are housing, commercial, etc. For example, in Vermont (whose population is only approx. 600,000), from 2002-2016, there have been 234 HTC projects that resulted in over $200 million in total development.
Overall, the HTC generates more dollars than it costs to implement. It gives money back to the government while benefitting local and state communities. Most everyone is catching on; in 2016, the HTC was used more than ever, according to the National Park Service and Rutgers University. From the National Trust for Historic Preservation: over the life of the program, the historic rehabilitation tax credit (HTC) has:
created more than 2.4 million good-paying local jobs
leveraged $131.8 billion in private investment in our communities;
used $25.2 billion in tax credits to generate more than $29.8 billion in federal tax revenue;
and preserved more than 42,293 buildings that form the historic fabric of our nation.
This video from the National Trust shares highlights of the HTC.
Think this just a concern for Democrats? Not true. President Ronald Reagan put the HTC into place and fully believed in it. Watch and listen here.
What can you do to help? Contact your representatives! Here is an easy way to send an email. And, even more effective, call them!
Abandoned Vermont: Addison Town Hall (Alternatively: What about Rural Preservation?)
February 9, 2016 February 9, 2016 9 Comments
An upfront disclaimer: The Addison Town Hall is owned by the Town of Addison. Technically, it's vacant, not abandoned. Due to its condition and the attention it requires, I categorize it as abandoned.
The Addison Town Hall sits at the center of the village of Addison Four Corners in Addison, Vermont, at the junction of VT Route 22A and VT Route 17. Addison is a rural agricultural community in Addison County, with some remaining working dairy farms. The shores of Lake Champlain make up the western edge of the county.
The Addison Town Hall and the Baptist Church are at the center of Addison Four Corners. Photo: January 2016.
The Addison Town Hall holds a place in my heart, because I studied the building during graduate school, and completed a building conditions assessment in 2010. And I passed through Addison Four Corners on my way to work at the Lake Champlain Bridge site for years. Since 2010, I've been visually monitoring the condition of the building.
The Addison Town Hall, as seen in January 2016.
The Town Hall was built in 1872 and has served as a school, a town hall, town offices, and grange hall. As community needs changed, the interior was adapted, including the second floor stage addition and partitions on the first floor. (See a few interior shots here.) School has not been in session since the 1950s. Today the town hall serves only as storage for the historical society and the neighboring Baptist church.
If memory serves, since October 2010 there have been a few frightening exterior developments.
There is a clear separation of the foundation stones, northeast corner. January 2016.
The northeast corner of the foundation is slipping, probably due to water damage. January 2016.
The same issues on the southeast corner of the building. January 2016.
The banks of windows would have been added when the standard school requirements of the 1930s were instated. January 2016. You can see all sorts of damage in this photo: collapsing back shed, weathering clapboards in need of a proper paint job, broken windows.
View from the southwest shows the larger picture of deterioration, including the cupola. January 2016.
The deterioration of the Addison Town Hall brings up a more important conversation in preservation than one building.
The Addison Town Hall is an example of building located in a still active community, but a community that is rural and without all of the financial resources to rehabilitate this structure. What happens to a building that is a visual and physical landmark in a town, when there is not an obvious use for it?
A community's needs change, and those changes often affect the buildings. Historic buildings with outdated purposes or those that are not up to code are left by the wayside with no plans and money. What will happen to them? Imagine if a town center lost one of its prominent buildings. Rural communities have small village centers, with only a few buildings to represent the entire village. Loss of a town hall or a church or a school is devastating.
Urban preservation is a great conversation and a fun topic. But, frankly, it's easier than rural preservation. There are more people, more opportunities for catalysts and funding. We should be talking more about alternative, creative uses for buildings in rural areas, where a one building win/loss can have much more of an impact than in an urban environment.
Addison Four Corners, January 2016.
YUP: Bikes, Beer & Buildings
July 20, 2015 July 20, 2015 Leave a comment
The media tells us, with valid evidence, that appreciation for historic buildings is on the upswing, and the number of craft brewers continues to grow, and alternate modes of transportation are catching on in urban areas.
Where can you find all of these in one place? Check out Rochester, New York. The Young Urban Preservationists ("YUP") of the Landmark Society of Western New York hosted its second annual BBB – Bikes, Beer & Buildings – scavenger hunt on Saturday July 11, 2015. Caitlin Meives (UVM HP Alum 2008), Preservation Planner with the Landmark Society, gave me the rundown on the event and the group.
PiP: Tell me about Bikes, Beer & Buildings.
CM: Bikes, Beer & Buildings is a great way to explore Rochester's neighborhoods, see some lesser known landmarks, and learn about ongoing preservation projects. Organized by The Landmark Society's Young Urban Preservationists ("YUPs"), BBB is Rochester's first bike-based scavenger hunt. The YUPs provide the clues and you (and your team of 1-4 people) hop on your bikes and hunt down the buildings (or architectural features, parks, structures, etc).
PiP: How many years running? Where did you get the idea and the name?
CM: This was our 2nd year. Last year, shortly after we formed, one of our steering committee members said he wanted to organized a bike scavenger hunt. So we did. Coming up with a clever name for events is always annoying so we thought, "Well, it involves three of our favorite things: bikes, beer and buildings….so why not just call it that!"
Happy participants! Photo provided by the Landmark Society for Western New York.
PiP: What's the purpose or goal of BBB?
CM: To have fun. To get out and see the city on two wheels. To see the exciting adaptive reuse projects that are happening all over the city. To see neighborhoods, parks, and buildings that a lot of people wouldn't otherwise see or notice. Big picture, we (the YUPs) are also trying to engage as many youngish folks as possible. There is a an ever-growing community of young people in the area, especially in the city of Rochester, who are committed to their communities and are preservationists at heart.
PiP: Was it a success?
CM: Yes, it's a big hit and we'll definitely do it again! This year we had 33 teams and just over 75 participants! We also had a bunch of local businesses and organizations who sponsored the event and provided in-kind donations of their awesome products for our prize baskets.
The beer garden! Photo courtesy of the Landmark Society of Western New York.
PiP: What was the best part of the event?
CM: Watching everyone enjoy a cold beer or the purple "Pedaler's Punch" that Lux Bar & Lounge prepared for our hot and tired cyclists.
Happy bikers and building lovers enjoying a cold beer. Photo courtesy of the Landmark Society of Western New York.
PiP: Who are the YUPs?
CM: The YUPs are a group of youngish folks interested in preservation and community revitalization. We come from various walks of life and various professions—lawyers, planners, doctors, veterinarians, architects, writers, artists—but we all have one thing in common: we care about our communities and we believe our historic resources play an important role in any community's revitalization.
What does "young" mean? Whatever you want it to! We're targeting those oft-maligned by the media "millennials" (aged 20 to about 40) but, more importantly, we want to connect with like-minded people who are invested in their communities and are young at heart.
PiP: Sounds awesome! Can you offer any advice for groups wanting to do something similar to BBB?
CM: Four tips for you:
You need a dedicated and committed group of organizers. You don't need a lot of people, you just need organized and committed people. In fact, if you have too many people it can become unwieldy. How you structure the organizing of an event like this depends on the structure and dynamics of your group. I happen to be one of the co-founders of the YUPs and I work for The Landmark Society, the organization with which the YUPs are affiliated, so it naturally falls to me to more or less lead the charge and to make sure we stay on track. In this case, delegating and giving people ownership of a task or an event can be challenging. However, in our 2nd year organizing this event, I found that people felt much more comfortable taking charge. If your group was formed more organically by people who just came together to form a group on their own, likely you'll all have that sense of ownership to begin with. Regardless, I think it's important to make sure someone is the point-person for the event as a whole or for each facet of the event. If everyone is running around doing a little bit of everything and no one is in charge of one thing, things can really easily slip through the cracks. Trust me. We had one or two last minute snafus.
Partnerships are key. Starting an event from scratch is tricky, especially if your group/organization is new and doesn't have a huge base from which to pull. Our first year, two days out from the scavenger hunt, we had three teams registered. Then one of our partners, a popular local blog that focuses on urban and preservation-related issues, shared the event through its social media. The flood gates opened and we breathed a huge sigh of relief.
Start small and work your way up. You don't want your first attempt to be a colossal failure. So don't set yourself up for failure by biting off more than you can chew or by expecting unrealistic numbers.
Learn and adapt. Your event won't be perfect the first, second, or third time around. But have fun with it, make sure your participants have fun, and get feedback from them.
PiP: Where can we find the Landmark Society or YUP on Social Media?
Instagram: @youngurbanpres
Search #yupROC ("ROC" is how locals refer to Rochester)
Facebook: Young Urban Preservationists
And check out Caitlin's TedX talk about Flour City
Thank you, Caitlin, YUPs, and The Landmark Society of Western New York! Great job on such a wonderful event.
Reclaim the Streets for Summer
We've talked about parklets previously, and you've probably seen them in one form or another, as they are popping up more and more. (Learn about parklets in this post, and check out Montreal examples here.) Technically, parklets are for the public – literally, mini resting areas/green spaces that borrow the street for people instead of cars and are free to the public. However, restaurants create their own versions of parklets in the form of outdoor seating in parking spaces – usually on wood decks at curb height. On my last visit to Montreal I noticed another one, seen below.
See the parklet across the street?
And diagonally across from the restaurant seating, I found an actual parklet. This one was quite simple: benches and planters. This set up gives people a spot to sit and gaze at the architecture, allows for more pedestrian use of the sidewalk, cafe space, and creates a more park like setting on this historic street. What do you think?
A parklet in Old Montreal.
Parklets and outdoor seating areas are reclaiming* the streets for pedestrians, which make summer even more fun (especially for those of us with long, cold winters). Choosing to cater to people rather than automobiles is an important aspect of placemaking, and it can make a big difference a city's vitality. Seen any lately? If you have, I'd love to see them. Use #presinpink on social media (Twitter, Instagram) to share!
*Reclaiming not to be confused with road construction reclamation. Just a transportation joke for you. haha. 😉
Church Turned Condos in Toronto
April 28, 2015 April 28, 2015 12 Comments
Large churches struggle to find alternative uses once they no longer serve as houses of worship. Whether located in a small town or a large city, too many churches sit empty and abandoned. Once in a while you'll come across a success story. This church in Toronto has been converted into condos. Take a look at the photos and let me know what you think.
The Victoria Presbyterian Church converted to condos.
Only being able to see these from the outside you can see that floors have been added. The balconies are clear glass. The original windows have been removed, but the fenestration remains.
Another view of the church, now condos.
A bit about the Victoria Lofts:
Converted from a turn-of-the-century church into 38 gorgeous units, this building is beautiful, rooted in history, and ideally located. Boasting soaring ceilings and gorgeous architecture including a dramatic sloping roof, a copper-trimmed steeple, romanesque arches and curved brick columns, suites range from 600 to 1800 square feet over one or two storeys. Originally the West Toronto Presbyterian Church, this stunning building has been a vital part of the Junction neighbourhood since 1885, when it first opened its doors. Renamed the Victoria Presbyterian Church to mark the Diamond Jubilee of Queen Victoria in 1897, this structure is one of several historic buildings in the area. Located near the West Toronto Rail Path, a multi-use 4km path that links several Toronto neighbourhoods, the Junction is well-connected and a haven for any one seeking to reduce their carbon-footprint. Spend an afternoon checking out the Junction Arts Festival, a neighbourhood display of music, dance and visual art, or take a fifteen-minute stroll south to High Park.
Apparently, converting churches into lofts is a thing in Toronto. Check out this post and this post. Do you want to live in a church? What do you think? A good idea? I'd like to see the inside. But, from the outside it looks pretty good. The windows would be better intact, but perhaps that wouldn't work for the residences. In that case, the structure remains as a landmark in the neighborhood and it is legible.
Do you have a church in your town that could serve as a residence?
"It's a Wonderful Life" Radio Play
Merry Christmas! What holiday traditions have you been doing? Are you starting new traditions? One of my favorite new traditions is to see the "It's a Wonderful Life" Live Radio Play. The Lost Nation Theater in Montpelier, VT has two shows every year, and this year the Champlain College Theater performed the play in Burlington. Written by Joe Landry, the play adapts the movie to a 1940s live radio play.
There are five cast members who read for multiple characters. As an audience member you see the characters read from their scripts at the microphone and then turn around to be another character. You see the sound effects being created off to the side and the stage manager holds signs for "applause" and "on air." The characters also sing commercial jingles during the play break.
For those who did not grow up listening to radio plays, it's fascinating. And for those who did, it's a nostalgic trip. TIf you love the movie, you'll love the play. (I cried at the same exact point in the play as in the movie.) This year I attended with some friends who had never seen the movie, but also loved the radio play. It's definitely a crowd pleaser and worth your time.
Looking for a performance near you? Check the listings. Though I see Lost Nation Theater is not listed, yet it's always performed. So ask around if you're not sure. Have you seen it? Will you?
Parklet Sighting in Montreal
July 9, 2014 July 9, 2014 3 Comments
What's lovelier than sitting outside on a warm summer day for lunch or enjoying a drink and your company at the end of the day? Many restaurants, particularly in our cold northern climate, do not have permanent outdoor seating. Why? Because sitting outside is only a good idea for a few months out of the year. For the rest of the year the sidewalks and patios are cold, covered in snow and inhospitable. But, come summertime we want to take advantage of that nice weather and soak it in as much as we can.
Remember learning about parklets? It's a conversion of parking space (temporary or permanent) into public space. Some are free for the public, outfitted with benches and plantings and designed to be meeting spaces for community members. Restaurants are catching on and creating outdoor dining areas from parking spaces – a twist on the "park" of parklets. While these are clearly affiliated with restaurants (meaning, not free for the public because you need to make a purchase), it's still a great use of space to bring the community to the street.
These restaurants parklets are from Montreal, Quebec. While they vary in design and style, all are enclosed and encompass part of the sidewalk and parking spaces.
A casual parklet with pink picnic tables.
This view shows the parklet platform half on the sidewalk, half in the street.
Enclosed in, metal fence. Across the street is the Old Port of Montreal.
Almost completely in the parking space, this parklet dresses up the scene with flower boxes and planting. And check out the view across the street. Beautiful buildings!
A closer view of the restaurant parklet. (Side note: In the life of a preservationist, I always feel like people think I'm taking photographs of them. Nope, sorry, just the environment!)
What do you think of restaurant parklets? Do you want to be eating next to traffic? It's a great use of space if your town or city has narrow sidewalks, but maybe sipping your drink and enjoying your meal is more difficult if a car is idling in traffic next to you. Yay or nay? Seen any in your neighborhood? Would you prefer a parklet for a restaurant or free for public use?
Abandoned Vermont: Highgate Falls Church
It's a good time to address underused churches in Vermont. The Vermont Historic Preservation & Downtown Conference features a work day at Christ Church on Thursday May 1, 2014. Too many of our churches sit empty with small, shrinking congregations, extremely limited (or no) funding, and an uncertain fate. The case of St. John's Episcopal Church in Highgate, VT is one of the many that is not abandoned, but is underused. It is used seasonally for weddings. Members of the church currently attend services in nearby Swanton, VT. Currently this church appears to be in good condition.
The Preservation Trust of Vermont works with Partners for Sacred Spaces and the Vermont Division for Historic Preservation to host retreats that will aid organizations in developing uses for their churches. (This year's is May 15-16 at the Grand Isle Lake House in Grand Isle, VT.)
Constructed in 1834.
Located in Highgate Falls, VT.
The rear of the church.
You can see clear through the window across the church. Is anything more lovely than a historic window?
Beautiful windows.
The sign on the front of the church.
This odd photo – pardon the blurry foreground, blame the iphone – shows the interior of the church. That's as much as I could see inside.
What a beauty. This church is located down the road from Highgate Manor and the Highgate Falls Lenticular truss. Read more about Highgate, a small town in Franklin County, northwestern Vermont.
Register for the 20th Annual Vermont Preservation Conference
Registration is open for Vermont's 20th Annual Historic Preservation & Downtown Conference, to be held in Island Pond on Friday May 2, 2014.
Highlights of this year's conference include (see the full program here):
Hands on Hammers work day at Christ Church in Island Pond on Thursday May 1. Come volunteer, lend a hand, and help us get this 1875 Gothic style church on the mend.
Keynote Speaker Nancy Boone, Federal Preservation Officer, HUD
Preservation Awards
Four concurrent afternoon session tracks, two of which feature 30 min "TED" style talks about historic preservation, architecture (porches, railroad depots, modern architecture, Vermont architecture), community, funding, history, folklore, and more. The other two tracks offer guided tour of the National Fish & Wildlife Refuge or Brighton State Park Mid-Century Modern Architecture.
Closing reception.
Hope to see you there. The presentations will be great, and the shorter tracks will allow you to learn more, hear more and not feel fidgety sitting for a 75 minute presentation. (I'll be presenting about Vermont's railroad depots with one of my colleagues.)
Island Pond is a unique town in the Northeast Kingdom. Come see! And pack your snow shoes. (It'll be May in Vermont, after all. Oh wait, it could be sunny and warm. You never know!)
Vermont Preservation Awards 2014
February 18, 2014 February 18, 2014 1 Comment
The 2014 Vermont Historic Preservation & Downtown Conference will be held on Friday May 2 in Island Pond. Part of the conference includes the Preservation Awards. Know of a good preservation project in Vermont? Now is the chance to highlight it. Read on for more information from the Preservation Trust of Vermont.
PRESERVATION TRUST OF VERMONT NOW ACCEPTING NOMINATIONS FOR 2014 PRESERVATION AWARDS
Burlington, February 12, 2014 — The Preservation Trust of Vermont is now accepting nominations for the 2014 Preservation Awards.
Since 1982, The Preservation Trust of Vermont has recognized outstanding contributions in the field of historic preservation. Awards are presented to the individuals and organizations that have made special contributions in preserving Vermont's historic architecture. Examples include the preservation or adaptive use of an historic property; educational and public information materials and programs; building trades and professional training; programming at historic properties; financial support; and special encouragement and leadership in the preservation field.
Nomination materials can be found on the Trust's website [click here]. The deadline for submissions is March 4. Awards will be presented at the Preservation Trust of Vermont's annual conference on May 2, 2014 in Island Pond, Vermont.
Award winners from 2013 and 2012 include: The Vermont Agency of Transportation for the Checkered House Bridge Project; Housing Vermont and Springfield Housing Unlimited for The Ellis Block, Springfield, Vermont; Larry & Lise Hamel for The Hardwick Inn, Hardwick, Vermont; the Town of Bristol for Holley Hall, Bristol, VT; the Putney Historical Society, Lyssa Papazian, Jeff Shumlin and Ming Chou for the Putney General Store Project; Birgit Deeds of Shelburne Farms, Patricia O'Donnell of Heritage Landscapes and Doug Porter of Porter and Associates for the Shelburne Farms Formal Garden Restoration Project; the Town Hall Theater, Inc. for the Town Hall Theater, Middlebury, VT; David Clem for the Wilder Center, Wilder, VT; Mimi Baird of the Calvin Coolidge Memorial Foundation, Plymouth Notch, VT; and the Friends of the Valley Foundation, the Wilmington Vermont Fund, FloodStock, the Deerfield Valley Rotary, Wilmington Vermont Flood Relief Fund, and Lisa Sullivan and Philip Taylor of Bartelby's Books, Wilmington, VT.
The Preservation Trust of Vermont is a nonprofit organization founded in 1980 to assist communities and individuals in the ongoing effort to preserve and use Vermont's rich collection of historic and architectural resources.
For more information, please contact Paul Bruhn, Executive Director, Preservation Trust of Vermont, 104 Church Street, Burlington, VT 05401, (802) 658-6647, Paul@ptvermont.org or visit www.ptvermont.org.
Here is a video of the Shelburne Farms Formal Garden Restoration – a 2012 award recipient.

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That's Gotta Be Smeg Ups
Looking back at Red Dwarf's blooper reels.
This week, Red Dwarf returns to audience shooting, for the second half of filming this year's Special. And while we'll eventually get an hour and a half of brand new Red Dwarf out of this production, a new set of filming dates also means the creation of something that for a lot of productions is a recurring irritation - but for Red Dwarf, has been an integral part of the show's DNA for a quarter of a century. We're talking, of course, about the Smeg Ups.
Well, Smeg Ups are what we call them, but elsewhere they're known as "bloopers", "outtakes", "fluffs", "flubs" or (in Asia) "NGs (no goods)". They're what happens when someone forgets a line, misses a cue, breaks a prop, "corpses" (breaks into laughter), or does anything else that wasn't in the script and can't be used in the show.
The practice of compiling such mistakes into "gag reels" is almost as old as the movie industry itself, but it was an American producer called Kermit Schaefer who first seized on the commercial potential of mistakes in their own right - selling his Pardon My Blooper albums in the 1950s and 1960s and coining the phrase in the first place.
Here in the UK, televised blooper compilations began with Denis Norden's It'll Be Alright On The Night in 1977, while the BBC began producing their own series, Auntie's Bloomers, in 1991. But these shows pulled together outtakes from a wide range of shows. As for a compilation of mistakes specific to a single show - who would possibly buy that?
The answer, of course, was Red Dwarf fans. While 1994 featured no new series of the show, there was still plenty of commercial activity, including the release of 1992's Series V on VHS. But the big Red Dwarf item in everyone's Christmas stockings that year was a 51-minute video whose cover promised "Red Dwarf as you've never seen it before... an hilarious, unmissable chance to look behind the scenes of the Red Dwarf universe and witness the cast and scenery fall apart."
The potential of a Red Dwarf outtakes compilation to draw fans in had been demonstrated when Rob and Doug turned up at the 1993 Dimension Jump convention with a rough cut blooper reel - but even so, Smeg Ups was a punt. Nothing like it had been produced in this way before - and what's more, it wasn't only trailblazing in terms of selling a reel of outtakes from a single show, but also in providing additional bonus material.
The clips were linked together by brand new footage, performed by Robert Llewellyn as Kryten and written by him and Doug - including a particularly fan-targeted section in which Kryten answered the "ten most asked questions about Red Dwarf", which were almost entirely continuity niggles. And even more excitingly, in an era before DVD special features, the tape featured the "original ending" - that is, the "urine recyc" postscript - of Series VI's Out of Time, still at that point the most recently-transmitted Red Dwarf episode!
Smeg Ups was released in November 1994, and was an immediate Christmas hit; so it was no surprise when a year later, we were treated to the follow-up, Smeg Outs. Where Ups had only featured outtakes from Series IV-VI, the sequel covered the first three series. This time around, Craig joined Robert for the links, and the bonus feature was the "full length smegmix" of Tongue Tied - at the time, the only place you could get a full-length version of the song and video, with added Claymation sequences to boot.
The success of both Smeg tapes led to other shows getting similar compilations - perhaps most notably, another Ed Bye-directed series, Bottom, sold plenty of copies of its 18-rated Bottom Fluff tape in 1996 - but meanwhile, it now became the case that no Red Dwarf production could pass without its Smeg Ups getting compiled.
Red Dwarf Night in 1998 saw another new compilation produced, with clips from the previous videos added to brand new Series VII outtakes and yet more new links. And when the DVD releases began in 2002, each individual series got its own dedicated compilation. This tradition has carried on throughout each new production, too - from Back to Earth through Series X, XI and XII, there's always a new set of Smeg Ups on the disc to enjoy.
The Smeg Ups have become such a key part of Red Dwarf lore that many moments from them are as memorable and quotable to fans as the episodes they derive from - and it's something that the cast themselves play up to. Over the course of a long Red Dwarf shooting night, it's possible for energy levels to flag if the rhythm of scenes is broken up by unavoidable mistakes. But a Kenneth Williams impersonation from Chris here, a Northern-accented grump from Robert there, or a well-timed chorus of all the cast giving a David Coleman-esque "EEEEEXTRAORDINARY!" can be just the tonic to keep the audience laughing - all the more so because it's a reminder of beloved moments from those original tapes.
So while a smooth, hitch-free production is all anyone who makes a television show can ever dream of, at least here at Red Dwarf we know that if anything does go wrong, there's going to be that little bit extra to enjoy once the shows are completed...
The Red Dwarf special will air on Dave later in 2020!
Got a question about Red Dwarf or this website? Check out our FAQ section and see if we've got an answer for you!
© 2021 Grant Naylor Productions. All rights reserved.


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Q: Excel file download in C# not working in Google Chrome This code is working when I am going to download a file using IE but when I tried in google chrome, it is not working. Why?
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        var details = from cat in db.Events_Category_tbl
                      join can in db.Candidates_Info_tbl on cat.events_category_id equals can.events_category_id
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                      select new Candidates
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                          candidates_fullname = can.candidates_fullname,
                          candidates_info_id = can.candidates_info_id,
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                          no_of_votes = can.no_of_votes.Value
                      };

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A: public ActionResult Excel_Reports() {
        //events query
        var events = db.Events_Info_tbl.Where(x => x.is_active == true).FirstOrDefault();
        ViewBag.events_name = events.events_name;

        var details = from cat in db.Events_Category_tbl
                      join can in db.Candidates_Info_tbl on cat.events_category_id equals can.events_category_id
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                      select new Candidates
                      {
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                          candidates_fullname = can.candidates_fullname,
                          candidates_info_id = can.candidates_info_id,
                          events_category_id = cat.events_category_id,
                          no_of_votes = can.no_of_votes.Value
                      };

        HttpContext.Response.AddHeader("content-disposition", "attachment; filename= Election_Results " + DateTime.Now.Year.ToString() + ".xls");
        this.Response.ContentType = "application/vnd.ms-excel";

        return View(details);
    }

This is my revised code and it works both in IE and Google Chrome.


The Related Cos. plans to build an 18-story office building on the north end of CityPlace, a move that could boost efforts to link the West Palm Beach mixed-use center to the rest of downtown and further develop the city's core urban district.
360 Rosemary is slated to rise at the corner of Rosemary Avenue and Evernia Street, the first in a series of steps designed to expand and update CityPlace, a shopping, dining and residential center built by Related.
The 285,000-square-foot tower will be across from Publix. The supermarket was courted for the ground floor space, but a Related official said this week that Publix is staying put at CityPlace. The office tower instead will feature another retailer.
"It's a big building for our market," said Neil Merin, chairman of NAI/Merin Hunter Codman in West Palm Beach.
Related tried to build another office tower next to CityPlace a few years ago, but it was unable to obtain enough tenants willing to pre-lease space in the project, dubbed Gateway Tower.
In 2014, Related pulled the Gateway Tower plan. The next year, it unveiled a different idea: The Restoration Hardware furniture gallery, which opened last year.


A WDH Community Grant has helped Love2Act drama club to buy new costumes and props for their production with a £646 cash boost.
WDH has awarded the Wakefield Music Collective £500 to help them hold the annual music festival.
Catch A Falling Star, an adult mental health support group was awarded £780 by WDH's Community Grant Scheme.
The WDH Community Grant Scheme is now open for local community groups and voluntary clubs to apply for up to £1,500. The cash boost can help towards existing services, buying equipment or paying for an event. The aim is to increase community spirit and enhance the quality of life for local people. Karen Deeley from Eastmoor Community Garden Association, whose art workshop project received funding from WDH, told us what the grant meant to her. "Five art workshops have taken place and the project has proved to be a wonderful experience. Children aged between three and seven participated and created underwater scene art, willow wreathes and clay models. As well as getting arty, people enjoyed exploring the community garden during their visits and learning about all the produce grown there. On behalf of the Eastmoor Community Garden Association, I thank WDH for the support. Without the grant received, none of this would have been possible." Applications are open from 7 August to 22 September 2017. For more information click here.
Members of the Chinwag Club are delighted to be able to carry on with their activities thanks to a grant of £1500 from WDH. The Club, for people over 50, meets every Monday afternoon at Balne Lane Community Centre. The Club provides an opportunity for older people to make friends and keep active. The group play bingo, cards and do chair based exercises. They often organise guest speakers and people to teach a variety of crafts and activities. Violet Chaltone, one member of the Club said: "It can feel really lonely when you live on your own. I enjoy coming to the Club for company. This is my regular activity to look forward every week." Chris Croxall, Tenant Involvement Officer at WDH said: "The area needs more organisations like Chinwag Club. Some of the members are disabled or on low income and the Club gives them a chance to socialise. By coming together regularly it improves the quality of life and avoids isolation. " The grant will help them to pay towards the annual rent and the cost of running the Club. The club always welcomes new members. If you would like to join or know someone who would be interested, please contact Balne Lane Community Centre on 01924 373558. Applications for WDH Community Grant Scheme will be open again on 7 August 2017. For more information please visit http://www.wdh.co.uk/OurCommunities.


Text critical study is often elusive for serious bible students. But it shouldn't be. And with the powerful tools in Logos 6, studying textual criticism is easier than ever. But to get the most out of these powerful features, you need resources specially tagged to power them. That's why we created the Textual Variants Collection.
Before we dive into the benefits of the Textual Variants Collection, let's dig into the Textual Variants tool itself. In this video, one of our Logos Pros demonstrates how to incorporate this powerful tool into your study.
The Textual Variants Collectionincludes all the essential resources to begin an in-depth study of any difficult text-critical passage. Here are some of the most noteworthy resources featured in this collection.
These are just some of the resources. Plus, with Dynamic Pricing, you get a discount for products you already own. Get it now.


When two defenders (opponents) are playing the ball between each other and it then deflects off one of them to an attacker in an offside position. If the attacker then take possession of the ball, is that an offside offence?
No - Being passed by an opponent is not an offside offence.
... A player in an offside position receiving the ball from an opponent who deliberately plays the ball (except from a deliberate save by any opponent) is not considered to have gained an advantage (hence not being offside).


I love telling stories, but I don't like knowing I have to fight to the edge of insanity to convince someone that a little bit of the bizarre is really worth it. The best example is Iggins flying away from the crashed elevator at the end of Gameslave 2. We could not just end the episode and have it implied that Iggins died in the crash because that would be bad, and killing children is bad, and bad things... are bad.
We had a taste of that in Bestest Friend, where Keef falls off the roof and explodes. Our quick fix was just adding some dialogue offscreen so that you know he's okay, but then instead of a simple "Oh dear, that annoying child exploded" you get "Oh dear, that child exploded and is asking if anyone wants waffles and now there's Gir stirring batter like some evil puppet master."
If I have to fix something, I like to fix it in the spirit of whatever I'm working on. So those ZIM fixes, although done begrudgingly, often made me like the end result even more. In the Gameslave 2 case, we were told that Iggins had to be alive. So I decided that Iggins would fly out of the rubble like Superman. This actually resulted in lengthy discussions, meetings, and conference calls with higher-ups from the network, all because Iggins flies at the end. I mean, the kid is SO not dead, so very healthy that he now has the ability to FLY!! How much better can you get than that? They thought we were making fun of them. That's when I blew my head off in frustration and became a crime-fighting ghost.
IGN DVD: Makes sense. What was the original target demographic Nick had for Invader Zim?
Jhonen: The original plan, the one they sold me on, was that they were looking to catch some of that older audience Cartoon Network was getting. Nick's a monstrous network, and they're not hurting for ratings, but nobody really thinks of them in terms of cool shows like Pete N' Pete or Ren and Stimpy anymore. So they wanted something "edgy", and even went so far as to make that wiggly "edgy" gesture with their hands that implies... "edgy."
What ended up happening is that as ZIM got closer to being finished, there were no other shows being worked on that fit in with this 'wiggly finger gesture' block that Nick had seemed so thrilled about. We ended up premiering, sammiched between Fairly Oddparents and Rocket Power - two shows perfect for kids, but not the kind of kids I wanted to make shows for. They created this 30 minute chasm of nightmares that the kids had to cross between musical numbers and extreme sports toddlers on skates.
Rather than change the show into something it wasn't, I just went on giving them the show they didn't quite know they were asking for. Like it or not, they were responsible and helped me make something that I'm proud of, that makes children cry. Go me!
Rikki Simons and his wife.
IGN DVD: Why didn't Nick consider shipping the cartoon over to MTV, like they did with Ren and Stimpy?
Jhonen: That I can't say for sure. We asked them to, when it became apparent that Nick was the "place for kids" but not "kids who want their eyes ripped out." As far as I know, Nick was all about burying the show with ever-changing time slots. Any move to a channel where it might get decent attention was not an attractive one to them.
When you're proud of something, working with a crew that enjoys what they're doing, you just want people to appreciate your work. Getting lucky with a network that backs you is a dream. We didn't have that, so we spent a lot of time in a crying huddle.
IGN DVD: You brought fellow comic artist Roman Dirge on as a writer and did many of the voices yourselves. Was there ever any opposition to not using talent exclusively from the animation industry?
Jhonen: Not so much from the higher ups. There were people who had come from very traditional animation backgrounds and most of then were just damned nice and glad to be working on something a little different. There were a few of those rare stereotype guys who were there just to look down on anyone who just didn't have experience (myself included). I came from comics, and there I am in charge of the show, so you learn to expect some difficulty, even from people who are supposed to be working for you, in realizing what's in your head.
There was the opinion that I should relinquish control to someone who comes from the world of animation, who might not actually have the imagination or humor that was right for what I was trying to do. I respect a person for their talent. And some of the guys working with me, though new to animation, were giving me so much more than a lot of the 'seasoned pros' could do. It's the freaks that surprise you, and the show, for the most part, found a nice balance of freak power and technical skill from both types of people.


We offer a four-year apprenticeship program to all of our entry-level field personnel. It is not required to have any prior electrical knowledge to enter the Apprenticeship Program. During the four years of training, each individual will experience several areas of field training. Ranging from working on service truck for residential, commercial and industrial electrical projects. This allows maximum exposure to the many different aspects of the industry. It educates each individual on how to become the future leaders in our company. After the apprentices have completed their four years, they are required to take the South Carolina State Journeyman exam. We encourage all of our employees to participate in our training programs so they can advance in the field. We encourage our employees to always focus on professional development and we are committed to helping them achieve career satisfaction.
Electricians are the only trade in the construction industry that are recognized as professionals.


text:
Byron, Jagger or Joni: who's best at barbs?
CRAIG BROWN
WHAT is the world's bitchiest profession? It's a close-run thing. Hairdressers have long had a poor reputation for camaraderie.
'Not being rude or anything, but who on earth did your hair last?' they always ask, pulling a face. Or does this say more about my hair than about them?
I've noticed, too, that pest control officers never lose a chance to put their competitors down, tut-tutting at the previous positioning of those little trays of poison. And plumbers love to stare aghast at leaky pipes before sighing: 'Dear oh dear, you've had a cowboy in.'
Dentists and car mechanics can be almost as bad. I wonder if anyone has ever thought of opening a one-stop shop, combining dentistry and car repair? After all, the technique is much the same. Whether it's your mouth or your bonnet, they ask you to open wide. Then, before you can say knife, they reel backwards and demand to know who is to blame.
Of course, no one is entirely saintly in this regard. When two newspaper columnists meet, they tend to scoff at other columnists. I remember my dear father-in-law, Colin Welch, late of this parish, saying of one up-and-coming young columnist: 'But why do they print her pieces? Someone must know. Surely it can't just be to make her look foolish?'
Of all the professions, poets have earned a reputation for being gentle, quietly spoken types, far too sensitive and unworldly to badmouth their fellow poets.
The truth is strikingly different. In my experience, they seethe with envy, redeploying any skill with words to make withering remarks about rival poets who sell better, or win more awards. Some years ago, at the Aldeburgh Poetry Festival in Suffolk, two poets got into a fist-fight in the street outside the hall, after one of them had heckled the other.
There is, of course, a long history of poet-on-poet thumpery. 'Here are Johnny Keats' p***-a-bed poetry,' said Keats's fellow poet, Lord Byron, just over 200 years ago. 'No more Keats, I entreat: flay him alive; if some of you don't, I must skin him myself. There is no bearing the drivelling idiotism of the Mankin.'
But the two professions vying for the number-one spot of the world's most vitriolic must surely be a) senior Tory MPs and b) veteran rock stars.
Every few months, an 'influential' (ie, crusty) Tory MP publishes diaries or memoirs full of rude remarks about his fellow Tories. These create a stir for a week or two, before being swiftly remaindered. The last to do this was Sir Alan Duncan, who called Mark Francois 'a horrid little man', Michael Gove 'a wacky weirdo', Dominic Raab 'a self-important, humourless bore', and so on.
But these Westminster insults have grown tired and hand-me-down. Old rock stars are starting to exhibit much more oomph.
Recently, Sir Paul McCartney described The Beatles' rivals, The Rolling Stones, as 'a blues cover band'. In turn, Sir Mick Jagger pointed out that The Beatles never toured arenas, like the Stones. 'They broke up before the touring business started for real ... We started stadium gigs in the 1970s and are still doing them now. That's the real difference between these two bands. One band is unbelievably luckily still playing in stadiums and then the other band doesn't exist.'
Roger Daltrey of The Who has just weighed into the great debate, observing that the Stones were never up to much, even in their prime. 'If you were outside a pub and you heard that music coming out of a pub some night, you'd think, "Well that's a mediocre pub band."' In his autobiography, Daltrey also turned on his own band, accusing all three of them of spite and envy.
Other rock stars have been equally snippety about each other. Robbie Williams once called Noel Gallagher 'a mean-spirited dwarf'. In turn, Gallagher called Williams 'the fat dancer from Take That'. Likewise, Morrissey called Robert Smith of The Cure 'a fat clown with make-up', and Smith said of Morrissey: 'If he says not to eat meat, then I'll eat meat. That's how much I hate Morrissey.'
Even gentler, more saintly singers can be surprisingly acidic. After Bob Dylan fell asleep when Joni Mitchell sang him songs from her album Court And Spark, she got her revenge by telling the LA Times: 'Bob is not authentic at all. He's a plagiarist, and his name and voice are fake. Everything about Bob is a deception.'
Let this be a warning to hairdressers, plumbers and politicians: if you wish to regain your crowns, it's time to look to your laurels.
Picture: Getty
More Craig Brown
I'm dreadfully sorry for eating you, says Jaws
Dear Sir... the elephant in the room is miffed!
Dinner with the duchess — bores off the menu...
Yikes! The Jenga's fallen into the gravy
It's high time you were out of those PJs!
What's your score in the Meg Quiz?
Jackie Weaver's shaken, stirred... and the new 007
Don't be Dopey — Snow White is 100% TRUE!
Should I stay or should I go to the party?


Then it was on. Every Brazilian score or rebound cheap football shirts was met with a thunderous roar. Every Argentine basket, every trip down the floor,was met with boos, jeers and whistles, and every replay, too, at cheap replica football shirts least until it registered in collective consciousness that this was basketball; there would be quite a lot of scoring..
The audience were even classicfootballshirts treated to a brand new song, expected to be on their sixth album. 'Heart Soul' has the makings of another classic, and the response to it was absolutely football shirts brilliant. Then Danny announced that it was his brother Richard's birthday (that's the guitarist!), and he even got a cake and blew out all the candles.
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Would like to stay ahead of that number, Cristi said. More creative we can get in terms of being able to plant more trees, the better off we going to be in the future. Council referred the pilot program to the budget committee to sign off on the re direction of funds and determine if 3.5 per cent is the right amount..
That said, there is good work in this show which doesn't need any explanation. Hannah Mooney's still lives and landscape paintings look traditional, almost anachronistic, but she combines a modesty of approach with such evident skill that one is scarcely bothered. William Braithwaite's sculptures of Escher like staircases in concrete with metal embellishments, beams and frames, show a real feel for materials, and for balancing solidity and space.
So that's it, a very personal selection of the world's most evocative football shirts. I'm conscious of some I've left off the list. Leave some comments and let me know your pick. retro football shirts So, is it really still a case of never the twain shall meet? Edinburgh's Alison Melton believes so albeit to a lesser degree than before. But the MD of Miss Love Weddings believes real madrid kit it's not only clothes that bailiwick of jersey 20p show the cities' style differences. "When you get off the train in Glasgow's Queen classic football shirts Street station, you can smell the fake tan," she laughs.


What's included in my Full Privilege Membership?
Stop by for a tour of our facility and receive a guest pass to try to the Randolph Y for free!
Hydrospin bikes, boxing bags, aqua-bells, trampolines, Tsunami Balance Boards & more!
All group fitness classes are included in your membership! Reach your fitness goals and lead an active and healthy lifestyle. From low-impact exercise, stretching and yoga to SPINNING and Zumba, you'll find a group fitness class that's fun, supportive and keeps you moving.
Our Life Fitness cardio equipment features Swipe Touch screen navigability and personalization options that put the world at your fingertips! Log on or sync your Android or Apple devices to our internet connected Discover consoles to access your personal content, pre-set workouts and equipment settings; take advantage of tone of On-Demand entertainment and interactive Lifescape courses.
With a swipe of a finger, navigate seamlessly between crisp, clear screens to choose the entertainment and workouts you want!
Full Pneumatic Circuit research backed strength training and fitness equipment used by top trainers and professional sports teams world-wide. Using the unique pneumatics, Keiser provides safe and effective training for everyone from the elite athlete to the older adult.
Premium Selectorized Equipment have QR codes on the equipment that you can scan to watch a tutorial on that piece of equipment.
Babysitting is available for members' children while parents or guardians utilize the Y facility. The parent must not leave the building. We reserve the right to refuse a child admittance to babysitting based on illness. The babysitting room is a Peanut Free Zone. Babysitting is free to family members or $1.00 per half hour for all other memberships (i.e. adult, senior, etc. except basic youth members) Maximum of 2 hours.
Children can hang out in the activity center while their parents use the facility. Complete with a chalkboard wall, tons of games, knock-hockey & more! The Activity Center is a Peanut-Free Zone. The activity center is free to family members or $1.00 per half hour for all other memberships (i.e. adult, senior, etc. except basic youth members) Maximum of 2 hours.
*Follows Randolph School District Schedule. Activity Center will be open 9:00 am - 1:00 pm when Randolph Schools have scheduled school closings.