text:
Harold Davis
harold@photoblog2.com
www.photoblog2.com
Harold Davis is honored as a printmaking master by Moab Paper
Moab Paper is pleased to announce that photographer and artist Harold Davis has been added to the Moab Masters program.
BriefingWire.com, 4/17/2012 - Moab Paper's prestigious Masters program includes photography greats such as Barbara Bordnick, Robert Farber and Ryszard Horowitz. Harold Davis is the latest addition to this select group of artists, all of whom pride themselves on their mastery of the art and craft of fine digital printmaking.
Harold Davis states, "I adore working with the hand-crafted Moab substrates, and in particular I am infatuated with Slickrock Metallic for much of my printmaking. It is bold and dramatic, and at the same time paradoxically subtle. In my monochromatic imagery I strive to extend the dynamic range, and Slickrock supports this with a multidimensional look. Slickrock prints show an incredible range of tonality in both color and black & white. It's also particularly interesting the way the metallic pearl transposes for white---one impact is that Slickrock prints shift in their presentation of negative space as the light they are viewed with also shifts. Highly recommended!"
Marc Schotland, Vice President of Marketing & Global development at Legion Paper adds, "We are excited to announce the addition of photographer Harold Davis to our Moab Masters program. Harold is a renowned photographer, artist and author who offers a unique vision and voice to the Moab Masters program. Harold's meticulous printing skills are present in every print he produces, and we're thrilled that he chooses Moab as the paper to support his images."
About Moab Paper: With product names like Entrada, Colorado, and Lasal, it's easy to see the source of inspiration for Legion Paper's Moab brand. Created in Moab, UT surrounded by the endless red rock wonders of Arches and Canyonlands National Parks, the Colorado River, and the LaSal Mountains, the Moab line of archival, digital imaging papers continues to rely on that inspiration to design premium solutions for digital photographers and artists.
Moab is part of the Legion Paper family of products, North America's premier distributor of fine art papers and museum board sourced from mills around the world, is committed to developing innovative products, which empower visual thinkers to share their inspiration.
Legion Paper maintains offices in New York City, Los Angeles and Moab with distribution facilities in Los Angeles and New Jersey.
About Harold Davis: Legendary photographer and artist Harold Davis believes that advances in the technology and craft of digital photography have created an entirely new medium that begins with photography and continues as digital art. Harold's extraordinary imagery builds on the masterworks of the past while embracing revolutionary innovations in photography. His stunning prints are widely admired and collected.


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Willis "Gator" Jackson ( à Miami - à New York) est un saxophoniste ténor de jazz américain.

Il joue avec le chanteur Herb Jeffries puis avec Cootie Williams (1947-1949) avant de diriger son propre groupe, enregistrant sous son nom dès 1950.

Il accompagne aussi la chanteuse Ruth Brown, dont il est le mari, ainsi que le chanteur Little Willie John. Puis, il signe chez Prestige et débute en 1959 une longue série d'enregistrements avec une petite formation comprenant un organiste. Jack McDuff, Freddie Roach, Butch Cornell, Jackie Ivory, et Carl Wilson ont fait partie de son groupe, de même que les guitaristes Bill Jennings, Pat Martino et Boogaloo Joe Jones. En 1973, après avoir songé à arrêter la musique, il signe chez Muse pour une nouvelle série d'excellents enregistrements, côtoyant notamment Charles Earland, Von Freeman, Sonny Phillips, Mickey Tucker et Groove Holmes avec lequel il fait une tournée en France en 1980.

Willis Jackson s'était inspiré à ses débuts d'Illinois Jacquet. Il excelle dans le blues et les ballades, grâce à un son moelleux incomparable.

Discographie

En tant que leader
Please Mr. Jackson (Prestige, 1959) - avec Jack McDuff et Bill Jennings
Cool "Gator" (Prestige, 1959–60) avec Jack McDuff et Bill Jennings [aussi sorti comme Keep on a Blowin]
Blue Gator (Prestige, 1959–60)
Cookin' Sherry (Prestige, 1959-60 1961)
Together Again! (Prestige, 1959-60 [1965]) - avec Jack McDuff
Really Groovin (Prestige, 1961)
In My Solitude (Moodsville, 1961)
Together Again, Again (Prestige 1959-1961 [1966]) - avec Brother Jack McDuff
Thunderbird (Prestige, 1962)
Johnny "Hammond" Cooks with Gator Tail (Prestige, 1962) - avec Johnny "Hammond" Smith
Bossa Nova Plus (Prestige, 1962) [also released as Shuckin''']Neapolitan Nights (Prestige, 1962)Loose... (Prestige, 1963)Grease 'n' Gravy (Prestige, 1963)The Good Life (Prestige, 1963)More Gravy (Prestige, 1963)Boss Shoutin (Prestige, 1964)Jackson's Action! (Prestige, 1964)Live! Action (Prestige, 1964 [1966])Soul Night/Live! (Prestige, 1964 [1966])Tell It... (Prestige, 1964 [1967])
Gator Tails (Verve, 1964) [aussi sorti comme Willis Jackson]Smoking with Willis (Cadet, 1965)Soul Grabber (Prestige, 1967)Star Bag (Prestige, 1968)Swivelhips (Prestige, 1968)Gator's Groove (Prestige, 1968)Mellow Blues (Upfront, 1970)Gatorade (Prestige, 1971)Recording Session (Big Chance, 1972) [aussi sorti comme Plays Around With Hits (Jazz Trip), 1974]West Africa (Muse, 1973)Headed and Gutted (Muse, 1974)The Way We Were (Atlantic, 1975)Funky Reggae (Trip, 1976)In the Alley (Muse, 1976)Plays with Feeling (Cotillion), 1976The Gator Horn (Muse, 1977)Bar Wars (Muse, 1977)Single Action - avec Pat Martino (Muse, 1978)Lockin' Horns - avec Von Freeman (Muse, 1978)In Chateauneuf du Pape (Black and Blue, 1980) - aussi sorti comme Ya Understand Me? (Muse, 1984)Nothin' Butt (Muse, 1980)

CompilationsThe Best Of Willis Jackson - Willis Jackson With Brother Jack McDuff (Prestige), 1972 compilationOn My Own (Whiskey, Women, And ... Record Company), 1986 compilation of fifties tracksThe Best Of Willis Jackson Volume One - Gator's Groove (Ace), 1988 compilation of Prestige recordingsLegends Of Acid Jazz - Willis Jackson (Prestige), 1998 compilation of "Blue Gator" & "Cookin' Sherry"Legends Of Acid Jazz - Keep on a Blowin (Prestige), 1999 compilation of "Keep on a Blowin'" & "Thunderbird"At Large (Prestige), 2000 compilationWillis Jackson With Pat Martino – Gravy (Prestige), 2001 compilationWillis Jackson With Jack McDuff – Together Again! (Prestige), 2003 compilationAfter Hours (Prestige), 2004 compilation of "Loose..." & "Soul Grabber"
En tant que sideman
Avec Ruth Brown Ruth Brown (Atlantic, 1957)

 Sources
 The Prestige Label (Ruppli) (Greenwood Press, 1980)
 Dictionnaire du jazz'' (Panassié, Gauthier) (Albin Michel, 1987)

Liens externes

Saxophoniste ténor américain de jazz
Compositeur américain de jazz
Musicien afro-américain
Naissance en avril 1932
Naissance à Miami
Décès à 55 ans
Décès à New York
Décès en octobre 1987
Artiste de Delmark Records

redpajama_set_name: RedPajamaWikipedia


raised in the San Francisco Bay Area, Kelly Nygaard moved to Los Angeles in 2008 to attend USC's School of Cinematic Arts.
After graduation, she received the incredible opportunity to work as Terrence Malick's assistant on the set of Knight of Cups, and spent the next few years shadowing directors in the commercial world until she decided to delve into directing herself.
Kelly has been directing commercials for the last two years, having completed over 10 spots for brands including FIAT, Redvines, The Donor Network, and New Amsterdam Vodka. She found her strength in the emotional storytelling of docu style films for Nintendo, stop the bleed, and Ad Council.
This work won her recognition by SHOOT Magazine as an emerging director in 2017.
As she moves into narrative projects, she's passionate about concepts that bring women's stories to the screen... because we can be badasses, too.


The schnauzers come in three different sizes; standard, giant and Miniature. The miniature schnauzer also known as dwarf schnauzers came from breeding small standard schnauzers with Affenpinschers and possible poodles too. The mini's only grow to roughly 30-36cm tall and weigh between 7-10kg but their personalities aren't small at all!
The Mini Schnauzers are full or character. They are generally very playful and energetic and get along with everyone. They are great pets for families and they are known to get along well with children and other dogs. They are very loving and affectionate making them a great companion dog. These intelligent dogs can be stubborn at times so make sure to train them early on. It's important the Mini Schnauzer knows who the pack leader is otherwise they may develop small dog syndrome where they believe they are the boss. It's important to keep this excitable little breed physically and mentally stimulated to help with health and behavioral issues.
A long walk or jog a day will keep this breed happy as well as some playtime with human or dog friends. It is also good to brush these dogs daily to prevent knots or matting. They have a long wiry coat that typically needs to be clipped twice a year. The usual clipping style for a Mini Schnauzer is for the upper body to be cut short and left slightly longer around the legs, head and underparts. Around the face will require regular trimming and grooming to keep any knots or matting from around the eyes, mouth and chin. It might take a bit of care with their coat however this breed sheds little to no hair and are great pets for allergy sufferers.
The Schnauzers originated from Germany getting their name from the German word 'Schnauze' meaning 'Muzzle'. They were bred for 'Ratting' where they chase, catch and kill vermin. The Mini Schnauzer is now used for many different things such as hunting, tracking and competitive obedience as well as companion dogs.


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New girls' hostel open at Lulanzi!
The opening of the new hostel at Lulanzi Secondary School is already transforming the lives of the girls who live there. Seventy-two girls have moved in and more are expected.
School hostel places are a dream come true for poor girl students. Before moving into the hostel, many of the Lulanzi girls had to wake before dawn to do domestic chores before walking many kilometres to school, often without eating, and knowing that bad things could happen to them on the way – young girls are constantly vulnerable to men who want to force, bribe or entice them into sexual relationships.
The hostel, deep in rural southern Tanzania, about 20 kilometres outside Iringa, has been built by the Lulanzi community with financial support from Lyra and the Michael Matthews Foundation.
Students say that their lives in their villages made it almost impossible to study at home. Roseneth, who lives with her grandmother, used to have to get up at 5am to do the "cooking, fetching water, collecting firewood, preparing food for seven people" before walking 10 kilometres to schools through "rain, cloud and strong winds early in the morning with an empty stomach." With hindsight, she doesn't know how she did it.
Food shortages are endemic in the area and girls often go without food, so covering the costs of the three regular meals a day that the hostel provides proved out of reach for many families. Now, though, the hostel has managed to lower fees from $214 to $166 a year, by juggling costs, purchasing food in bulk and planting three acres of maize.
Students say they are enjoying the supportive atmosphere, and working hard towards fulfilling their dreams of becoming teachers, nurses and journalists.
Completing secondary education will also mean they are likely to have smaller, more manageable families in the future, and be able give back to their communities.
The girls say their hostel friends encourage them when they struggle and that they, in turn, support their friends.
"God bless the people who implemented the project," says Roseneth.
Newer Post12,000 miles of "sneakernet"


text:
package teams.voot;

import org.springframework.beans.factory.annotation.Autowired;
import org.springframework.data.domain.PageRequest;
import org.springframework.web.bind.annotation.GetMapping;
import org.springframework.web.bind.annotation.PathVariable;
import org.springframework.web.bind.annotation.RequestParam;
import org.springframework.web.bind.annotation.RestController;
import teams.interceptor.LoginInterceptor;
import teams.migration.Membership;
import teams.migration.Team;
import teams.repository.MembershipRepository;
import teams.repository.TeamRepository;
import teams.service.TeamExternalGroupDao;

import java.util.Arrays;
import java.util.Collection;
import java.util.List;
import java.util.Optional;
import java.util.stream.StreamSupport;

import static java.util.stream.Collectors.toList;

@RestController
public class VootApiController {

  @Autowired
  private TeamRepository teamRepository;

  @Autowired
  private MembershipRepository membershipRepository;

  @Autowired
  private TeamExternalGroupDao teamExternalGroupDao;

  @GetMapping("/" + LoginInterceptor.API_VOOT_URL+ "/group/{localGroupId}")
  public Group findByLocalGroupId(@PathVariable("localGroupId") String localGroupId) {
    Team team = resolveOptionalOrThrow(teamRepository.findByUrn(localGroupId), localGroupId);
    return convertTeamToGroup(team);
  }

  @GetMapping("/" + LoginInterceptor.API_VOOT_URL+ "/linked-locals")
  public List<Group> linkedLocalTeamsGroup(@RequestParam("externalGroupIds") String fullyQualifiedExternalGroupIds) {
    String[] ids = fullyQualifiedExternalGroupIds.split(",");
    List<String> urns = teamExternalGroupDao.getByExternalGroupIdentifiers(Arrays.asList(ids)).stream()
      .map(teamExternalGroup -> teamExternalGroup.getGrouperTeamId())
      .collect(toList());
    return teamRepository.findByUrnIn(urns).stream().map(this::convertTeamToGroup).collect(toList());
  }

  @GetMapping("/" + LoginInterceptor.API_VOOT_URL+ "/linked-externals")
  public List<String> linkedExternalGroupIds(@RequestParam("teamId") String localGroupUrn) {
    return teamExternalGroupDao.getByTeamIdentifier(localGroupUrn).stream()
      .map(teamExternalGroup -> teamExternalGroup.getExternalGroup().getIdentifier())
      .collect(toList());
  }

  @GetMapping("/" + LoginInterceptor.API_VOOT_URL+ "/members/{localGroupId}")
  public List<Member> getMembers(@PathVariable("localGroupId") String localGroupId) {
    Team team = resolveOptionalOrThrow(teamRepository.findByUrn(localGroupId), localGroupId);
    return team.getMemberships().stream().map(this::convertMembershipToMember).collect(toList());
  }

  @GetMapping("/" + LoginInterceptor.API_VOOT_URL + "/groups")
  public List<Group> getAllGroups() {
    return StreamSupport.stream(teamRepository.findAll().spliterator(), false).map(this::convertTeamToGroup).collect(toList());
  }

  @GetMapping("/" + LoginInterceptor.API_VOOT_URL + "/user/{uid}/groups")
  public List<Group> getGroupsForMember(@PathVariable("uid") String uid) {
    return teamRepository.findByMembershipsUrnPersonOrderByNameAsc(uid, new PageRequest(0, Integer.MAX_VALUE))
      .getContent()
      .stream()
      .map(this::convertTeamToGroup)
      .collect(toList());
  }

  @GetMapping("/" + LoginInterceptor.API_VOOT_URL + "/user/{uid}/groups/{groupId}")
  public Group getGroupsForMemberAndTeamUrn(@PathVariable("uid") String uid, @PathVariable("groupId") String groupId) {
    Optional<Membership> membershipOptional = membershipRepository.findByUrnTeamAndUrnPerson(groupId, uid);
    Membership membership = membershipOptional.orElseThrow(
      () -> new ResourceNotFoundException(String.format("Membership for team %s and Person %s not found", groupId, uid)));
    return this.convertTeamToGroup(membership.getTeam());
  }

  private Member convertMembershipToMember(Membership membership) {
    return new Member(membership.getUrnPerson(), membership.getPerson().getName(), membership.getPerson().getEmail());
  }

  private <T> T resolveOptionalOrThrow(Optional<T> optional, String urn) {
    return optional.orElseThrow(() -> new ResourceNotFoundException(String.format("Non existent Team with urn %s", urn)));
  }

  private Group convertTeamToGroup(Team team) {
    return new Group(team.getUrn(),team.getName(), team.getDescription(), "member" );
  }

}

redpajama_set_name: RedPajamaGithub


Best Facial Hair Bleaching Cream For Sensitive Skin Howeverthere certainly are some things that they do not let you know on the box concerning bleaching blond. This is exactly the reason why we exploited Boulder-based salon specialist, Casey Hebb, at The Down Town Refinery, to provide the 4-1-1 on hair that is white. Whether you're thinking about doing this yourself going to a salon, the following seven tips are indispensable to think of before choosing the dip.
In case you want to avoid an emergency buzz cut, then equip your self with all the truth before bleaching your hairloss. Semi-permanent hair colour offers natural hues which fade over time, and also permanent hair dyes mix the decolouration and colouring process. Bleach, but oxidizes the entire scalp, meaning it exists completely to strip the shade out of the hair. It's really a potentially invaluable software in your hair styling arsenal, however, it is additionally a potent compound which demands a great deal of knowhow to use it accurately.
Bleaching eliminates hair color as a result of the practice of oxidation. Bleaching products interrupt the hair's cuticle layer to allow it to be more porous, which allows hydrogen peroxide -- a important component of hair bleach -- to penetrate the manhood. Hydrogen peroxide oxidises the hair's pigment, stripping off the saliva and, as a result, its colour. Single bleaching can whiten your hair by as a lot of shades. Use a house hair-bleaching kit or flip to a stylist to get professional software. Based on how light you would like your hair, the approach normally takes 30 to 45 minutes. Often, shade is inserted following the bleaching process.
Bleaching often leaves hair drier, more delicate and less elastic than it was once. Its effects create your hair more prone to breakage and less manageable. Because the bleaching process increases the cuticles, your hair can appear faster readily. If you depart flaking on for too long, your hair can become whitened. Or wavy hair can take on a yellow hue, as the stripping method exposes the color of your entire hair protein jelly, which includes an all organic yellow shade. Exotic hair colors usually take on a red shade as keratin shines throughout.
Bleached hair necessitates more maintenance than your natural locks. Because hair bleaching advances the hair's sulfonic acid material, it needs more lubrication. Property kits consist of intensive leave-in conditioners, which needs to be applied nearly instantly right after bleaching. After the first bleaching, everyday cleansing and also other products help porous bleached hair maintain its moisture and shine. Pre-treatment shampoos and deep-conditioning remedies also support hair retain its elasticity if applied before bleaching.
Before you embark on on bleaching, take into consideration several esoteric tidbits about moving blond. For example, regardless of what some wonder magazines claim, lemon-juice isn't going to bleach your hair blond. It may very subtly lighten already fair hair immediately after lengthy sunlight coverage, yet. The Pregnancy Association recommends that expectant mothers wait patiently before second trimester before employing baldness or other compound treatments. At length, bleaching your hair it from donation programs, like Locks of Love, as bleached hair proceeds to worsen throughout the wig-manufacturing course of action Best Facial Hair Bleaching Cream For Sensitive Skin.
Related Post "Best Facial Hair Bleaching Cream For Sensitive Skin"


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Hockey Trades, Rumors & Signings
Nagy awarded $3M, Coyotes to accept
TSN.ca Staff
An NHL arbitrator has awarded Phoenix Coyotes forward Ladislav Nagy a one-year $3 million contract for the 2006-07 season.
The Coyotes will agree to the terms and Nagy will be under contract for the 2006-07 NHL Season.
Nagy, who notched 56 points in 51 games last season, earned $1.9 million last season, during which he ranked third on the team in point production with 56.
He underwent underwent knee surgery in February and missed the last 31 games of the season.
BE-LEAF-ABLE
That's quite a deal for a player that's been near PPG the last few years. I don't see Nagy play much, but I know that's he's injured often.
Maybe that played into him getting less than Briere did...
Either that, or the Arbitrator had mercy on Mr. Wayne.:dunno:
"It's not the way it's going to be. We have to be very, very patient and build this the right way. We have to go through a process. It may be painful. I hope it isn't. But we're prepared for all the bumps and pratfalls and potholes in the road ahead. I'm prepared for it anyway, or I wouldn't have come." - Ron Wilson, Head Coach of the Toronto Maple Leafs.
Third on the team with only 51 games played, I guess that's OK!! Not sure what they would have given him if he played the whole 82?? Scary to think about really!!!
panoo Aug 8, 2006

redpajama_set_name: RedPajamaCommonCrawl


It is important not only to understand who Christ is, but also what He accomplished on the cross and what His present ministry is. Why? Because what Christ did is crucial to our salvation and God's redemptive plan centers around the work of Christ.
This is important because some unbelievers claim Jesus did not die on the cross, but rather fainted and was later revived and later died in obscurity.
When Christ died on the cross, it was more than just an ordinary death.
1. Christ bore our sins on the cross.
2. Christ died in our place (as a substitute for us).
Substitution = one life given as a substitute for another; Christ dying instead of us.
C. It's significance - Why did Christ die and what did it accomplish?
1. Christ's death satisfied God's justice.
God judges His creation according to His moral standard and is fair in His judgment.
Why "death" as a penalty? Isn't spiritual separation from God forever a stricter penalty than the crime deserves?
(1) God is just, therefore He cannot be unfair, therefore the penalty of "death" cannot be unfair.
(2) So serious is disobedience to a holy and sovereign God that death is its just punishment.
God is the standard, not man and his understanding.
d. All human beings are born spiritually dead with a sin nature because they are descended from Adam.
e. The penalty of death must be paid before man could be restored in his standing before God.
Christ needed to become a man because man had to pay the penalty.
f. Christ became a man, died on the cross, and paid the penalty for man's sin, thus satisfying God's justice.
g. Man either accepts Christ's payment or rejects it.
If a person accepts that payment by accepting Christ, the penalty is paid for him and he is saved (justified).
If a person does not accept that payment by rejecting Christ, he pays the penalty himself in eternal separation from God and eternal punishment in hell.
h. God must punish sin and carry out the penalty if He is just.
If there is a God, then He must be just, then there must be a hell.
See (a) above -- God is just.
2. Christ's death satisfied God's holiness.
b. Because God is holy, He cannot be united with sinful men.
c. When man sinned, he became separated from God who is holy.
All men sinned and were separated in Adams's sin.
d. The only way man could be reunited with a holy God is through forgiveness of his sins.
e. Christ bore man's sins on the cross and thus provided forgiveness for man's sins.
f. If a person accepts Christ, the forgiveness of Christ provided by His death becomes effective in his behalf and he receives forgiveness for all his sins; past, present, and future. Thus, he becomes united to the holy God.
If a person does not accept Christ, the forgiveness Christ provided does not become effective in his behalf, he does not receive forgiveness of sins, he dies in his sins and is never reunited with the holy God.
II. The present ministry of Jesus Christ in our lives.
As believers, we enjoy a personal relationship with Jesus Christ (John 17:3).
A. Christ is the head of His church.
B. Christ intercedes for us before our Father in heaven.


The Downtown East Louisville streetscape brings curb appeal to the next level. Click to read more.
Getting to be a part of the Pikes Peak Region Peace Officers' Memorial is a true honor.
We had the privilege to be one of the subcontractors who worked on this AAA Interior Redesign.
Congratulations to all the award winners! See Winners Here!


I think it's the family. I think it's this fun, dysfunctional family that we've built over the course of 15 years, and there's a solid family unit there with Gibbs in that paternal position. And then you got his 'kids' all trying to do right by him and make him smile and make him happy and also catch the bad guys. It's great, so when you talk about these cast changes and how they've changed things, it is changing out sometimes different members of our family. We've been very blessed so far that some of the people that we've welcomed into the show -- like back when Cote de Pablo took over for Sasha Alexander way back in the day -- we've lucked out with a lot of our cast changes. We've welcomed in some amazing, amazing people, and I'm so glad we have Rocky Carroll, and we have Wilmer Valderrama and now Maria Bello and Diona as well.
The family dynamic that's felt by a TV show's cast isn't a new concept, even for a show that doesn't actually center on a traditional family unit. But then, very few fictional series make it all the way to 16 seasons on the air, so few can boast such longterm relationships between co-stars that could absolutely allow for legitimately familial connections to develop. A lot of people don't even get to spend 16 years in the same close vicinity as their brothers and sisters (and parents, in some cases), so some of the core NCIS cast members could very well be closer to each other than members of their own real-world families. That tight-knit kinship is obviously witnessed in NCIS' onscreen relationships, which Brian Dietzen labels as the show's biggest popularity-stretching element.
He extended the family metaphor to incorporate the various casting changes that NCIS has gone through over the years, from Caitlin coming and going to Ziva's touching farewell (and eventual offscreen death) to DiNozzo leaving to take care of a daughter he hadn't known about. And no one will forget Pauley Perrette's final NCIS episodes. In most cases, but not all, characters left in non-tragic ways that allowed for light-hearted reminders and references in later years, which is comparable to sporadic communications between long-distance family members. As well, bringing in fun new cast members is similar to how new relationships can help families continue growing and changing over time.
Interestingly, Brian Dietzen also points out how it's not just about the family unit itself, but how that vibe informs how the team tackles their cases each week. Here's how he put it.
We've been really, really fortunate in that, because I think people do tune in to see this cast of characters and this family and how we connect not only to one another, but how we connect to the cases each week. So it's kind of cool, there are other criminal procedurals where it's ripped from the headlines, and our show is really about the characters. I think that's what's led to some success for us.
That's an interesting take that not all TV viewers might have thought about. The Law & Order franchise has long been known for adapting real-life criminal cases for its plots, and the recent explosion of true crime TV has doubled down on putting more emphasis on sensational crimes themselves, sometimes at the expense of character development. NCIS, meanwhile, crafts some of its cases in ways that draw out certain elements of the characters' lives and personalities, which helps to further connect them with fans. And considering there's no end in sight to NCIS' run on CBS, I'd say their efforts have been successful.
Everyone who's been watching NCIS for years probably knows that the Season 15 DVD set, which was released on August 21, is full of special features focusing on everything viewers love. We have a handful of commentaries from the cast and crew on select episodes, the featurette "A Conversation with Mark Harmon and Joe Spano," and extras that cover "Friends and Enemies," Maria Bello's introduction, the season's biggest special effects sequences and stunts, and more behind-the-scenes looks at the storylines and the characters. Perhaps most intriguing to some will be the great David McCallum answering the Proust Questionnaire.
With millions of people waiting to see how a full NCIS season will look without longtime star Pauley Perrette as Abby Sciuto, Season 16 will debut on CBS on Tuesday, September 25, at 8:00 p.m. ET. To see what other viewer-beloved dramas will be airing around the same time, our fall TV premiere schedule will be of great service.


Earth Science. Developing an Early Interest in Science: A Preschool Science Curriculum. (3-Year-Olds).
Note: For the curricullm guide for "4 year olds", see PS 026 539. The project was also supported by the Kate B. Reynolds Charitable Trust, the Cannon Foundation, Glaxo Foundation, the North Carolina Math Science Alliance, and Alexander County Head Start.


text:
Keeping You In The Know
Welcome to our media pages which contain client advisories, articles, press releases and details about upcoming events.
Client Advisories
Oil on Troubled Waters: successful restructuring of Ocean Rig Group
Client Advisories|27 Sep 2017
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In Ocean Rig [1], the Grand Court sanctioned four inter-related schemes of arrangement (the "Schemes"), as part of a group restructuring of over US$3.69 billion of New York law governed debt – in value terms, the largest judicially approved restructuring in the Cayman Islands. In each case, the scheme companies moved their COMI from the Marshall Islands to the Cayman Islands not long before the Schemes were promoted; but that did not prevent the Schemes subsequently receiving recognition in parallel Chapter 15 proceedings.
Creditor participation and support at the scheme meetings was high, but there was opposition from a significant creditor, Highland Capital Management LP and affiliates ("Highland"), which voted against the proposed scheme of the parent company Ocean Rig UDW Inc ("UDW"), on which the other schemes were conditional. Highland also objected to the UDW scheme at both the convening hearing and the sanction hearing.
Highland's position changed over the course of the two hearings, but Highland's main arguments were that:
two class meetings, and not one, should be convened for the UDW scheme, which would have given Highland a sufficient interest to block the whole restructuring;
and/or the UDW scheme was unfair and Highland should be entirely carved out of the group restructuring.
The Proposed Schemes
In order to continue as a going concern, UDW, an international contractor of offshore deepwater drilling services, needed to restructure around US$3.69 billion of debt held directly by UDW or through three of its wholly owned subsidiaries ("DOV", "DFH", "DRH"; collectively the "Silo Companies" and collectively with UDW the "Group"). Four interlinked schemes were proposed within a 'light touch' provisional liquidation of UDW and the Silo Companies. There was a successful COMI shift of all four companies from the Marshall Islands to the Cayman Islands, which withstood an objection in the related US Chapter 15 proceedings [2].
DOV and DFH sought to compromise their secured term loan facilities of over US$3 billion plus accrued interest outstanding ("Term Loans"). DRH sought to compromise its secured notes with over US$450 million plus accrued interest outstanding ("DRH Notes").
UDW sought to compromise (i) unsecured notes issued by UDW with over US$130 million plus accrued interest outstanding ("UDW Notes") as well as (ii) UDW's guarantees of the Term Loans and the DRH Notes ("UDW Guarantees"). The distinctions between UDW noteholders and UDW guarantee creditors were at the core of this case.
The Schemes proposed a reduction of debt through an exchange for (mostly) equity, a smaller debt burden, and cash. If the Schemes were to fail, it was common ground that the result would be a liquidation of the Group, with value destruction for all creditors (i.e. all creditors would receive less in a liquidation than under the Schemes).
One of the features of the Group restructuring was that a funded Preserved Claims Trust ("PCT") was to be established to preserve, in particular, the claims to set aside alleged fraudulent conveyances that had been asserted by Highland in a draft complaint aimed at, among others, UDW's chief executive officer (George Economou) and chief financial officer (Anthony Kandylidis). Under the PCT, if the trustees considered that there was merit to the claims they could be pursued for the benefit of all UDW scheme creditors.
Highland's Objection
Objections to the restructuring had initially been raised not only by Highland but also by an ad hoc group of DRH noteholders ("DRH Group"). Negotiations between the Group and the DRH Group, represented by Campbells, led to a modified proposal being put before the Court, which allowed for a substantially increased recovery for DRH noteholders. As a result, the DRH Group was able to support the DRH and UDW schemes.
By the time the Schemes were presented to the Court at the convening hearing, therefore, the only objection being voiced was from Highland and related to the UDW scheme. Given that the schemes proposed in respect of the Silo Companies were conditional on sanction of the UDW scheme, however, Highland's objection threatened to block all of the Schemes.
Highland held 56.5% of the UDW Notes, and in that capacity was a creditor in the sum of around US$74m, representing around 2% of the total amount of the claims of UDW's scheme creditors. Highland objected to the UDW scheme on the bases of class composition and fairness.
Class Composition
Highland's key objection at the convening hearing related to the number of class meetings that should be convened in relation to the UDW scheme, it being common ground that there should be only one class in respect of the DRH, DFH, and DOV schemes.
Should the UDW scheme comprise one class (as proposed by UDW) or more than one class (as proposed by Highland)? If the UDW Notes were in a class of their own, as Highland proposed, Highland's majority ownership of those notes would allow it to block the UDW scheme and therefore prevent all the schemes from going ahead without modification.
The Court confirmed the two-stage test for class composition [3]:
Is there any difference between the strict legal rights of creditors either prior to or under the scheme?
If there is any difference, are the rights so dissimilar so as to make it impossible for those creditors to consult together with a view to their common interest? Or, on the assumption that the relevant scheme were to fail, is there objectively more to unite than divide the creditors of the proposed class, ignoring for that purpose any personal or extraneous interest or subjective motivation?
The main focus of Highland's attack was on the first stage of the test.
Stage 1 (existing rights): Highland argued that the UDW guarantee creditors had different existing rights from the UDW noteholders because, unlike the UDW noteholders, the UDW guarantee creditors had (i) security elsewhere in the group structure and (ii) dual recourse rights (i.e. they could sue and/or prove for the same debt in a liquidation of the relevant Silo Company as primary obligor as well as against UDW as guarantor).
The Court accepted UDW's argument that, when the Court compares existing rights of different creditors at stage 1, the Court must look only at the rights that each creditor is to release against the scheme company in question [4]. In other words, the Court could not consider security rights against other group companies or recourse against another group company for the same debt. To the extent that some English cases might be said to suggest otherwise, that is not good law in the Cayman Islands [5].
Stage 1 (rights under the scheme [6]): Highland also argued that the UDW guarantee creditors benefited from inducements which were never even offered to Highland or the UDW noteholders. Early signatories to a restructuring support agreement ("RSA") would receive consent fees and be reimbursed for their professional fees; but Highland was never invited to sign up to the RSA. The Court found that the consent fees were payable in respect of and out of the assets of the Silo Companies. That meant that they were not part of the quid pro quo for the release of rights at the UDW level – even if support for the Silo Companies necessarily required support for the UDW scheme on which the success of the Silo Companies' schemes depended.
Stage 2: The Court also found that there was, in any event, more to unite than to divide the creditors of the proposed single class at UDW, given the fact that the outcome, if the Schemes were to fail, was a Group liquidation that would leave all those creditors (including the UDW noteholders) in an economically worse position than under the Schemes. The difference in rights was not sufficiently dissimilar to prevent consultation together with a view to their common interest; the UDW guarantee creditors' security was found to be worthless (they were effectively unsecured) and the financial inducements were immaterial.
Highland argued that the UDW scheme was unfair and that Highland should be entirely carved out of the restructuring, so as to be able to pursue claims under the New York Debtor and Creditor Law arising out of alleged fraudulent conveyances from UDW; alternatively the Court should refuse to sanction the UDW scheme. In return for not being schemed, Highland would agree not to collect from UDW any sums due pursuant to the UDW Notes or any scheme consideration. It was common ground that the result of scheming Highland was that Highland would no longer be a creditor (Highland would be a shareholder in new UDW), and so could not file its claim in the USA.
On fairness, the question to be determined by the Court was whether the UDW class was fairly represented by those who attended the meeting (in person or by proxy) and whether the majority acted in good faith and did not coerce the minority in order to promote interests that were adverse to those of the class whom they purported to represent.
Although other challenges were made, Highland's key fairness objections were that:
the UDW majority had additional interests which motivated their vote in favour of the UDW scheme, and so their votes should be disregarded; and
scheming Highland would unfairly prevent Highland from pursuing a complaint under the New York Debtor and Creditor Law.
Additional Interests: Highland sought to argue that the voting had been unrepresentative and/or was affected by special interests. In particular, Highland contended that where a party's support for the scheme is based in part on different or additional interests to the class as a whole, that party's vote should be disregarded. As the UDW guarantee creditors had additional motivations to support the UDW scheme (their interests in the Silo Companies' schemes being sanctioned and their right to consent fees), Highland said that their votes in the UDW scheme meeting should be disregarded, leaving only Highland's 'no' vote to be taken into account.
The Court held that if a creditor is motivated by an additional interest to support a scheme, the Court is not thereby obliged to disregard that creditor's vote. The vote may be disregarded only if the additional interest clashes with and is adverse to the interests of the class. The Court approved the 'but for' approach taken by the English court in Apcoa whereby the objecting creditor must show that the majority could not have voted for the scheme, absent the additional interest [7]. On the facts the Court was satisfied that the UDW guarantee creditors could have voted for the UDW scheme, absent additional interests – relying in part on the fact that some UDW noteholders who had no other group debt voluntarily chose to support the UDW scheme [8].
Highland's Draft Complaint: The PCT preserved claims alleged in Highland's draft complaint for the purpose of the trustees being able to pursue them (if meritorious) for the benefit of all UDW scheme creditors. The Court held that there could be no unfairness to Highland if the UDW scheme resulted in all UDW creditors losing their standing to pursue claims which all those creditors would otherwise have had the right to pursue under the New York Debtor and Creditor Law: all UDW creditors were being treated equally [9]. Moreover, the PCT was a fairer way to deal with the alleged claims, since it would treat all UDW's scheme creditors ratably and would not give any priority to anyone.
In any event, the Court held that the UDW scheme could not be modified by the Court if the scheme company was opposed to the modification. As a matter of principle, the Judge's task was to consider whether the Schemes before the Court were fair and reasonable (without necessarily being the fairest, best or most reasonable), and not to undertake any comparative exercise between the proposed Schemes and hypothetical alternatives.
The successful Ocean Rig restructuring underscores the flexibility of Cayman schemes of arrangement. Moving the COMI of proposed scheme debtors to the Cayman Islands for the purposes of restructuring group debt, including where the debt is governed by New York law, provides debtors with an effective restructuring solution.
There was overwhelming creditor participation and support for the Schemes. The legal analysis supported the commercial imperative that Highland should not succeed in bringing down the Schemes, as a hold-out minority creditor, to the detriment of all other creditors.
The decision was grounded in commercial good sense in at least one other respect. Groups are commonly restructured by way of interlinked schemes of arrangement, and group creditors often have 'cross-holdings' (i.e. they hold debt owed by different scheme companies). The decisions on class composition and fairness in Ocean Rig are consistent with that commercial reality. The existence of cross-holdings should not lead to a proliferation of classes (the consequence of Highland's approach on class); and a creditor's vote should not be disregarded merely because it also has an additional interest in the successful promotion of an inter-related scheme. Otherwise, group restructuring by inter-related schemes of arrangement might be impracticable if not impossible.
Another interesting facet of the case was that the US and Cayman Courts approved a court-to-court protocol – not for co-operation between two sets of officeholders (since the same officeholders acted in both jurisdictions) but between the two Courts. This appears to be a first for the Cayman Islands and it reflects the spirit of discussions currently taking place in the Judicial Insolvency Network.
[1] Mr Justice Parker, unrep., 18 September 2017 (Cause Nos. FSD 100, 101, 102 and 103 of 2017)
[2] Although the group companies were previously all Marshall Islands entities, UDW was incorporated in the Cayman Islands in 2016 as a result of a transfer by continuation under Part XII of the Companies Law (2016 Rev.); and the Silo Companies were registered foreign companies under Part XIII of the Companies Law. Accordingly, the Cayman Islands Court had jurisdiction over each of UDW, DOV, DFH and DRH.
[3] Following the "modern approach" applied by the English Court in Re Apcoa Parking Holdings GmbH & Ors [2014] EWHC 3899 (Ch), per Hildyard J at [52].
[4] Judgment at [57], [66]-[68]
[5] Stemcor [2016] BCC 194 at [18] in reliance on Re Uniq [2012] 1 BCLC 783 at [24]. The Court considered these authorities on this issue during the course of argument, although they are not referred to in the judgment.
[6] Unlike with existing rights, the Court should compare benefits received by creditors from the restructuring as a whole, without confining itself to benefits conferred by the scheme company itself.
[7] Judgment at [93]-[95], [121]
[8] Judgment at [121]-[122]
[9] Judgment at [125]
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Morse Stick Keyer 2: how to use it! - TSP S.r.l.
Morse Stick Keyer 2: how to use it!
A new video from TSP S.r.l. shows how to use the "Morse Stick Keyer 2", the most light and small paddle for telegraphy of the world. The demostration is made using a well know YAESU FT-817. This paddle works very well with other radio too, for example with: FT450D, IC7000, IC7300, TS-480, KX3 and many more.
You can find all the information at the product page. Here below you can find the demo video (please activate the subtitles). Enjoy.
For more information please use the following form.


On the front page of algorfa.co.uk there is flight information, it doesn't tell you the gate number, but I wouldn't trust it anyway. Alicante change gate numbers at the last minute quite a bit.
£2 million expansion plan for Cornish Ice Cream!
Didn't we have change the recipe for ice cream like we did for chocolate?
"The proposal we want to develop is a deal that presents a great opportunity" for Chile, Peru, Mexico and Colombia, the Pacific Alliance member states.


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Home / Shop / All Rare Books / Books & Myself – John A. Hammerton (1944) (1st ed)
Books & Myself – John A. Hammerton (1944) (1st ed)
Title: Books and Myself
Author: John Alexander Hamilton
Publisher: Macdonald & Co., London. No date, but most likely the 1st edition of 1944.
Condition: Hardcover, fair. Fading to spine, especially severe at the edges. Some foxing, inscription to ffep. Attached to the endpaper is a letter from the author to a reader, dated 1944. With photographic plates. Binding tight, text unmarked. 343pp., app 8″ by 5.5″.
Categories: General & Others, All Rare Books Tag: First editions
The memoirs of John Alexander Hammerton, and influential figure in the early 20th century UK publishing scene.
About the author (from Wikipedia):
Sir John Alexander Hammerton (1871-1949) is described by the Dictionary of National Biography as "the most successful creator of large-scale works of reference that Britain has known".
Hammerton's first posts in journalism included a period in Nottingham, where he first met his lifelong collaborator and friend, Arthur Mee. In 1905, Hammerton joined Alfred Harmsworth's Amalgamated Press. He and Mee produced the Harmsworth Self-Educator.
Hammerton contributed to the first edition of Mee's Children's Encyclopædia, which was a fortnightly series from 1908 till 1910 before being published in eight large volumes. Hammerton's contribution consisted of compiling articles on 'Famous Books' and 'Poetry'.
Hammerton's greatest achievement was Harmsworth's Universal Encyclopædia. It was published first as a fortnightly series from 1920 to 1922. The Encyclopaedia sold 12 million copies throughout the English-speaking world.
In 1933, Hammerton's A Popular History of the Great War (in six volumes) was published. In his introduction to volume 1, Hammerton discusses the previous World War I series: 'Although it remains a storehouse of information for future students of the period, "The Great War", as that set of thirteen massive volumes was called, would now require to be largely re-written in light of later knowledge'.
Hammerton later edited a biography of J. M. Barrie and studies of Charles Dickens and Robert Louis Stevenson. He also wrote Other Things than War: Musings and Memories (1943), and an autobiography, Books and Myself.


This section brings together information about MTM-CNM from across the TREAT-NMD website. Much of the information here is especially relevant for individuals and families affected by MTM-CNM, but family doctors and researchers should also find something of interest.
Browse through this section for specific information about MTM-CNM, and also take a look at the other areas of our website for more general information about TREAT-NMD and the resources we offer.
Find out about various patient registries that are already operational or are at the planning stage.


text:
The First President
from George Washington
When George Washington died in 1799, General Henry Lee put his many achievements into just a few words. He said Washington was "first in war, first in peace, and first in the hearts of his countrymen."
Most people remember Washington as the nation's first president. However, he was also an outstanding military leader. He led the nation to victory in the American Revolution, an eight-year fight for independence from Britain. Americans respected him for his boldness and bravery in combat and for his loyalty to his soldiers during very tough times.
Washington always tried to be honest and true to his word. He had a personal code of right and wrong. He also had a strong sense of duty to his country. Shy and modest, he never expected to be the nation's first president—and he never sought the office—but when the nation's leaders convinced him that his country needed him, he agreed to serve. Luckily for us, as you will see, George Washington was the right person for the job.
Next topic in George Washington
Young George
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America in Washington's Time
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INTERIM MANAGEMENT STATEMENT – Q3 2019: Encouraging Additional Phase 3 Data Presented for Abicipar, and Start of Phase 1 Trial for MP0310, the First Immuno-oncology DARPin® with a Novel Therapeutic Design
Research & Development:
MP0310 (FAP x 4-1BB): First patient dosed in phase 1 trial for this tumor-localized immune-modulator, representing a key milestone as the first novel therapeutic design of an immuno-oncology DARPin® candidate in clincial development (in co-development with Amgen)
MP0250 (VEGF x HGF) in Multiple Myeloma: Update on ongoing phase 2 PI trial (in combination with Velcade®) to be provided at ASH and company's R&D Day in December 2019
Abicipar (VEGF):
FDA accepted Biologics License Application (BLA) and EMA validated Marketing Authorisation (MAA) in neovascular age-related macular degeneration (nAMD) in Q3 2019; U.S. launch, following FDA filing and review, expected mid-2020;
EU approval expected in H2 2020
Encouraging two-year data from phase 3 studies in nAMD presented at AAO meeting in San Francisco; abicipar expected to be the first anti-VEGF therapy to sustain initial vision gains on a consistent 12-week dosing interval
Research: R&D Day on December 12, 2019 in New York City will underline the company's continued progress and focus on novel therapeutic designs
Talent base with 133 full-time employees (+17% year-on-year), reflecting ongoing strong build-out of the organization, in both R&D and SG&A areas
Nicolas Leupin, M.D., MBA, started in his roles as Chief Medical Officer and Member of the Management Board effective September 1, 2019
Seth D. Lewis to join the company in November 2019 as Senior Vice President Investor Relations & Corporate Communications – Strategy, based in the company's Boston-area office
Strong financial position with CHF 112.3 million in cash and short-term deposits
FY 2019 expense guidance slightly reduced to CHF 55-60 million
Zurich-Schlieren, October 31, 2019. Molecular Partners AG (SIX: MOLN), a clinical-stage biotech company that is developing a new class of drugs known as DARPin® therapies*, announced today its Interim Management Statement for the period ending September 30, 2019.
"Abicipar represents the first DARPin® therapeutic to be accepted for review by FDA (U.S.) and EMA (EU), validating the potential of the DARPin® platform to yield candidates that fulfill all dimensions of development necessary for approval. We are convinced that the expected consistent 12-week dosing interval of Abicipar can bring benefit to patients," said Patrick Amstutz, Ph.D., Chief Executive Officer of Molecular Partners. "Additionally, we are proud that MP0310, our first candidate from our suite of novel therapeutic design immuno-oncology molecules, has successfully entered the clinic. We are recruiting patients to evaluate MP0310's ability to localize activation of the immune system to the tumor, potentially enabling higher anti-cancer activity without dose-limiting systemic side-effects."
Oncology: Update of MP0250 in multiple myeloma to be presented in Q4 19
MP0250 is a multi-DARPin® candidate that targets hepatocyte growth factor (HGF) and vascular endothelial growth factor (VEGF), two prominent tumor escape pathways, and has the potential to reverse adaptive resistance to standard of care cancer therapies.
The first phase 2 trial for MP0250 in combination with proteasome inhibitors (PIs) is evaluating MP0250 in combination with bortezomib (Velcade®) and dexamethasone in patients with multiple myeloma who have failed standard therapies. The company will provide an update on the phase 2 trial data at both the ASH conference in Orlando and at the company's R&D Day in New York City.
Immuno-oncology: Initiation of phase 1 trial of MP0310, a novel tumor-localized immunotherapy
For MP0310, also referred to by Amgen as AMG 506, the first patient has been enrolled and dosed in the first-in-human study of MP0310 as a single agent in patients with advanced solid tumors. The trial will evaluate the optimal dose range of MP0310 in preparation for planned combination studies with Amgen's oncology pipeline products.
MP0310 is the first product candidate in Molecular Partners' DARPin® immuno-oncology pipeline. It is designed to activate immune cells specifically in the tumor and not in the rest of the body, potentially delivering greater efficacy with fewer side effects. Preclinical studies of MP0310 have demonstrated immune T cell activation restricted to solid tumor tissues, and strong CD8 T cell activation and expansion in vitro and in vivo. Additionally, preclinical data show MP0310 does not induce strong systemic activation of CD8 T cells and, therefore, has lower risk of the systemic side effects and toxicities.
The MP0310-CP101 trial intends to enroll up to 54 patients at three sites in France. The open-label, dose-escalation study will evaluate the safety, tolerability and pharmacokinetics of MP0310 in patients with locally advanced or metastatic solid tumors.
Abicipar: Additional encouraging two-year data from phase 3 studies in nAMD presented at AAO
Allergan and Molecular Partners announced the two-year data from the CEDAR and SEQUOIA clinical studies of abicipar in patients with neovascular (wet) age-related macular degeneration (nAMD) at the annual meeting of the American Academy of Ophthalmology (AAO) in San Francisco. In the second year of these studies, quarterly-dosed of abicipar resulted in the maintenance of visual gains comparable to monthly-dosed ranibizumab (Lucentis®).
Through week 104, patients received 2 mg of abicipar every 8 weeks or every 12 weeks, or 0.5 mg of ranibizumab every 4 weeks. At week 104 in the pooled phase 3 data, the proportion of patients with stable vision was 93%, 90% and 94% in 8-week abicipar, 12-week abicipar and 4-week ranibizumab treatment regimens, respectively. This continuation of stable vision in the second year further reinforces the ability of abicipar to deliver effective outcomes with consistent quarterly dosing for the majority of patients.
Mean changes in best-corrected visual acuity (BCVA) seen in year two were similar when compared to year one across all treatment arms. Central retinal thickness (CRT) continued to decrease during year two when compared to year one. CRT for patients treated with abicipar dosed quarterly and every 8 weeks were similar to ranibizumab dosed every 4 weeks through week 104. Overall incidence rates of treatment-emergent adverse events at the end of year two were comparable between treatment groups. The pooled rate of new cases of intraocular inflammation in year two for patients who received abicipar in the 8- and 12-week arms was 1.9%, which is similar to the ranibizumab arm of 1%.
The data shown at AAO therefore reinforce a sustained response at two years with less frequent dosing of abicipar compared to standard of care therapy.
Abicipar: FDA accepted the BLA and EMA the MAA for patients with nAMD in Q3 2019, key milestones for the company and its DARPin® technology platform
In the third quarter 2019, the U.S. Food and Drug Administration (FDA) accepted a Biologics License Application (BLA) and the European Medicines Agency (EMA) validated a Marketing Authorisation Application (MAA) for abicipar pegol, a novel, investigational DARPin® therapy, in patients with neovascular (wet) age-related macular degeneration (nAMD). The FDA is expected to take action on the BLA mid-2020. A decision from the European Commission is expected in the second half of 2020.
The BLA and MAA filings are based on data from two phase 3 trials, CEDAR and SEQUOIA, which supported the non-inferior efficacy of the abicipar quarterly dosing regimen to maintain vision gains with more than 50 percent fewer injections versus ranibizumab (13 vs. 6) dosed monthly in the first year. The FDA filing acceptance marked an important milestone for the DARPin® technology as abicipar becomes our first DARPin® candidate to receive filing acceptance by the FDA.
Balance sheet: Strong cash and equity positions as of September 2019
Molecular Partners' financial performance for the first nine months of 2019 reflects the cash collection in Q1 2019 of the USD 50 million upfront payment from Amgen for the MP0310 collaboration. Cash and short-term deposits increased by CHF 13.3 million over the first nine months of 2019 to CHF 112.3 million as of September 30, 2019 (June 30, 2019: CHF 123.3 million).
As of September 30, 2019, the company employed 133 FTEs, a 17% increase year-over-year, with approximately 85% of employees serving in R&D functions.
For the remainder of 2019, Molecular Partners will continue to advance its DARPin® candidates within its immuno-oncology research pipeline, specifically the FAP x CD40 molecule, the CD3 DARPin® T cell-engager platform as well as the peptide-MHC programs, and expects to present an update at the company's R&D Day in New York City.
In immuno-oncology, recruitment of patients for the phase 1 trial of MP0310 (AMG 506) that is in collaboration with partner Amgen will continue in Q4 2019.
In oncology, the company expects to present additional data from its ongoing phase 2 trial of MP0250 in patients with multiple myeloma (MM) in combination with Velcade® in December 2019, both at the ASH conference as well as at the company's R&D Day. The company further plans to present initial safety data for MP0274, the company's proprietary DARPin® candidate for the treatment of HER2-positive cancer, in Q4 2019.
In ophthalmology, Molecular Partners continues to work closely with its partner Allergan in the preparation and education of the market for the expected market launch of abicipar in 2020. The FDA and EMA are currently reviewing the respective regulatory applications for abicipar in patients with nAMD. The FDA is expected to take action on the BLA in mid-2020. A decision from the European Commission is expected in the second half of 2020. Allergan further indicated its intention to launch the phase 3 study for abicipar in DME in 2020.
For the full year 2019, at constant exchange rates, the company trimmed the guidance for expected total expenses to CHF 55-60 million, of which around CHF 5 million will be non-cash effective costs for share-based payments, IFRS pension accounting and depreciations. This guidance reflects the discontinuation of the NSCLC trial for MP0250 as well as the reduced investment in manufacturing scale-up for phase 3 material trials for MP0250. Capital expenditures in FY 2019 are expected to be approximately CHF 2 million.
This guidance is subject to the progress of the pipeline, mainly driven by the speed of enrollment of patients in clinical trials, manufacturing costs, and data from research and development projects. No guidance can be provided with regard to net cash flow projections. Timelines and potential milestone payments for existing and potentially new partnerships are not disclosed.
December 12, 2019 R&D Day in New York City
February 6, 2020 Publication of Full-year Results 2019 (unaudited)
April 29, 2020 Annual General Meeting
DARPin® therapeutics are a new class of protein therapeutics opening an extra dimension of multi-specificity and multi-functionality. DARPin® candidates can engage more than five targets, offering potential benefits over those offered by conventional monoclonal antibodies or other currently available protein therapeutics. The DARPin® technology is a fast and cost-effective drug discovery engine, producing drug candidates with ideal properties for development and very high production yields.
With their low immunogenicity and long half-life in the bloodstream and the eye, DARPin® therapeutics have the potential to advance modern medicine and significantly improve the treatment of serious diseases, including cancer and sight-threatening disorders. Molecular Partners is partnering with Allergan to advance clinical programs in ophthalmology and is advancing a proprietary pipeline of DARPin® drug candidates in oncology and immuno-oncology. The most advanced global product candidate in partnership with Allergan is abicipar, a molecule for which phase 3 data have been filed to the respective regulators in both the US and in Europe,. Several DARPin® molecules for various ophthalmic indications are also in preclinical development. The most advanced DARPin® therapeutic candidate wholly owned by Molecular Partners, MP0250, is in phase 2 clinical development for the treatment of hematological tumors. MP0274, the second-most advanced DARPin® candidate owned by Molecular Partners, binds to Her2 and inhibits downstream signaling, which leads to induction of apoptosis. MP0274 is currently in phase 1. The company's lead immuno-oncology product candidate MP0310 is a FAP x 4-1BB multi-DARPin® therapeutic candidate designed to locally activate immune cells in the tumor by binding to FAP on tumor stromal cells (localizer) and co-stimulating T cells via 4-1BB (immune modulator). Molecular Partners has closed a collaboration agreement with Amgen for the exclusive clinical development and commercialization of MP0310. The molecule has entered in phase 1 in H2 2019. Molecular Partners is also advancing a growing preclinical and research pipeline in immuno-oncology that features its "I/O toolbox" and additional development programs such as novel therapeutic desigens to target peptide-MHC comoplexes. DARPin® is a registered trademark owned by Molecular Partners AG.
Molecular Partners AG is a clinical-stage biotech company that is developing a new class of therapies known as DARPin® therapeutics. The company continues to attract talented individuals who share the passion to develop breakthrough medicines for serious diseases. Molecular Partners has compounds in various stages of clinical and preclinical development and several more in the research stage, with a current focus on oncology and immuno-oncology. The company establishes research and development partnerships with leading pharmaceutical companies and is backed by established biotech investors.
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Admission to Xoximilco Park; Transportation service with a specialized guide and operator; Tour by Xoximilco canals; Dinner with authentic Mexican cuisine; Open bar of tequila shots, beer, sodas and fruit-flavored water.
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Available: Monday through Saturday; Pickup time: 6:30pm.
Child rates only apply for children ages 5 to 11 years old or with a height of 1 meter to 1.40 meters.


At the end of June I had the blessing of being on a mission trip to Minneapolis with some of our youth and adults. We were exposed to homelessness, poverty, and life's challenges in ways we have not experienced before. During the days we worked at food shelves, community centers, food banks, and thrift stores focused on helping people with intellectual disabilities. In the evenings we had activities encouraging us to think about what life is like for people struggling financially. For example, one evening in groups of five we were tasked to take the city bus to a grocery store, buy dinner supplies for 5 people with only $7.25, and then make our meal. We also heard a personal witness from Cynthia, a woman who overcame abuse and poverty with help from others, and now works to help people move beyond poverty. During our busy week we also found time to pray and play together.


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« The CASCA/ACURA TMT Advisory Committee (CATAC) Is Up and Running
Square Kilometre Array (SKA) Update »
Astrosat Observatory Update
March 20, 2017 - 1:44 pm | Uncategorized
By John Hutchings (NRC)
(Cassiopeia – Spring/printemps 2017)
ISRO's Astrosat observatory is in regular operations and all instruments are working well. The UVIT telescopes, for which Canada supplied the photon-counting detectors, are performing well above spec and have no sign of degradation after 18 months in orbit. The accompanying image shows the centre of M31 in the FUV (roughly 150nm wavelength), from a program of Denis Leahy. The hot population around the nucleus, dust clouds, and young clusters in the spiral arms, are evident. Other Canadian observing programs range from X-ray binaries to star-forming galaxies, AGN, and galaxy clusters.
Refinements in drift correction and distortion corrections by CSA's science support, Joe Postma, are producing matched images with 0.9" to 1.0" resolution in various filters, and the ability to do time analysis of fluxes. UVIT and the three X-ray instruments all observe together, allowing for multi-wavelength investigations. Canada has guaranteed 5% of observing time, and cycles will be for a full year, beginning this October. Expect a call for proposals around June. Astrosat will also be open for a quota of international proposals in future, and discussions are under way for a single TAC process. Proposal pressure from India remains high.


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Martin Kejval steps down from the CBCC Executive Committee
The co-founder of the Czech British Chamber of Commerce, Martin Kejval, announced his decision to step down from the CBCC Executive Committee.
Today, during the CBCC Annual General Meeting, Chairman Ladislav Hornan officially announced Martin Kejval's decision to step down from the CBCC Executive Committee.
Mr Kejval is one of the founders of the Czech British Chamber of Commerce in London, alongside the current chairman Ladislav Hornan. The decision to launch the Chamber resulted from the initiative of the former ambassador HE Jan Winkler in 2008. Martin has been responsible for marketing and communications and over the years participated in many successful events; for instance CBCC's presence at the Czech House during the London Olympics in 2012, breakfast with president Vaclav Klaus at Coleridge's, the Polo Cup Tournament, several joint events with the Czech Centre in London, and Czech Tourism with his former company Techo.
Ladislav Hornan, the Chairman of the Chamber, personally thanked Martin for his work in the Executive Committee over the past 8 years and his undoubted contribution to CBCC.
Whilst the Chamber is losing a committed and valuable Executive Committee member, Martin will continue to look after the Chamber's IT technology and cloud hosting. He will remain an active member and is also going to participate in organising certain upcoming events.
Martin Kejval
Martin was born in Prague, is married and is a father of two children. Co-founder of the Czech British Chamber of Commerce, and executive member (2008-2016) responsible for Public Relations and Marketing, he has been living in the UK since 2001. Martin is currently Managing Director and founder of a social media marketing company BRS Network Ltd.
Until 2014 Martin was CEO of Ahrend Holdings UK and Co-Managing Director of Techo UK Ltd. Between 2001 and 2010 he held a position of Director of Finance and Operations of Techo UK, which became a part of the leading European office furniture group Royal Ahrend in 2008.
Before joining UK operations Martin was a senior Board member of Techo Headquarters in Prague. As Operations Director he was responsible for company operations, logistics and production. He has over 18 years' experience in corporate management and finance and as a Board member of Techo Group was responsible for international IT development.
In addition, Martin is Chairman of International Hotel Management Group, which successfully operates hotels in the Czech Republic. Martin has completed five years of study at the British Open University in Milton Keynes in management and finance; in 2004 was awarded a Diploma in Management (DipMgmt) and in 2006 Master of Business Administration (MBA).
BRS Network Ltd, 25 Britton Street, EC1M 5NY London
M: 07977 282 398, E: mkejval@brsnetwork.co.uk, L: uk.linkedin.com/pub/martin-kejval , W: brsnetwork.co.uk


Billscape 24/7 dedicated! :: The server!
This is a pretty awesome server! i mean yeah a lot of servers are out there but none like this! and the forums are nicely done, everything! the gameplay is great, the client, the monsters/npcs, shops, prices, skilling, everything. all i wanna say is good job bill!
lunaghand wrote: This is a pretty awesome server! i mean yeah a lot of servers are out there but none like this! and the forums are nicely done, everything! the gameplay is great, the client, the monsters/npcs, shops, prices, skilling, everything. all i wanna say is good job bill!
ye well done, just the only down fall not enough players.
bennyaka wrote: ye well done, just the only down fall not enough players.
It is awesome but it be better if there was more emotes, items, shops, monsters, and players not to bring it all down but it would be better with more players and monsters.
WOOT! IM A SENIOR MEMBER!


These buttons are public domain and as such are free for you to use, modify, and redistribute as you see fit. If these button graphics are useful to you, please consider linking to us!
A total of 42 buttons are included; 21 of each type (square and rectangle), and in 21 different colour schemes. Each button has a white background and soft shadow, though this can easily be modified in the SVG files distributed with this download.


APPREX PVT LTD recruiting Passenger Service Associate candidates nearby Kolkata.APPREX PVT LTD vacancies for Passenger Service Associate is recruited through Written-test, Face to Face Interview etc.
APPREX PVT LTD Company recruits a lot of candidates every year based on the skills . The candidates with Other Graduate, 12th Pass (HSE), 10th Pass (SSC), BCA, Other Course, Diploma, B.Com, BA are selected to full fill the vacancies in Customer Service / Tech Support job field. The candidates nearby Kolkata can apply for Passenger Service Associate position in APPREX PVT LTD. All candidates should have a degree or post-graduation in the required field based on the requirement mentioned. The jobs are available in Full Time basis. When it comes to the APPREX PVT LTD recruitment, candidates are mostly chosen for the department of Customer Service / Tech Support . To learn more about the current jobs and other details, it is better to go through official site of APPREX PVT LTD and Freshersworld. Find the latest jobs near you and near your home. So, that you don't need to relocate. The Freshersworld is a leading employment portal that researches the official site of APPREX PVT LTD and provides all the details about the current vacancies, the application process, selection process, interview test details, important dates and other information. Search and apply for the top job positions in APPREX PVT LTD and near your city and get a secured career.


Our Technology Advantage is that Homeowner/Investors, can access their personal Rental Investment 24/7 through a Customized Owner's Portal, that provides an operating record of the property.
Collection of all rents, deposits and expenses.
Monthly Statements Via Email or Mail.
End of the year reports & IRS Form 1099, for tax purposes.
We offer On-Line Rent Payments for Tenants to expedite Owner's funds.
We invest in advanced technology system to provide you with the best service and manage your properties efficiently and effectively. We have chosen Property Management & Accounting Software called (http://appfolio.com ) AppFolio Property Manager.
The enables us to respond faster provide better service to both the Homeowner and Tenant. We can securely access information about all properties at any time and from anywhere. Sensitive data is securely housed in a state -of- art data center, and backed up regularly and automatically.
We can create electronic work orders and communicate with vendors to expedite repairs and quality service to tenants.
We also are able to effectively market your property to fill vacancies sooner. We professionally advertise your properties on our Web Site(s), Realtor.com and many other Web Sites.


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Q: How to force one bot.on runs before another bot.on I create a MS azure chatbot, and I using bot.on(.....);
Here is my sample code.
bot.on("event", function (event) {
    if (event.name === "greeting") {
        locale = event.value;
        console.log("event runs");
        eventTimestamp = event.timestamp;
    }
});

bot.on("conversationUpdate", function (message) {
 .............
});

I want to make event runs before the conversationUpdate....Is there a way to do it in azure bot framework.
Thanks.

A: You can use recieve middleware. It will run before conversationUpdate
bot.use({
    recieve: function(event, next){
        locale = event.textLocale; // you can use textLocale
        console.log("event runs");
        eventTimestamp = event.timestamp; // this event also provides timestamp
        next(); // don't forget to call next
    }
});

redpajama_set_name: RedPajamaStackExchange


Try this super fresh and seasonal dish this fall! Creamy Vegan Butternut Squash Linguine with Fried Sage is perfect on a chilly October night and goes great with a glass of wine.
Butternut squash pasta is a great vegetarian meal or side dish.
Heat oil in a large skillet over medium heat. Once the oil is shimmering, add the sage and toss to coat. Let the sage get crispy before transferring it to a small bowl. Sprinkle it lightly with sea salt and set the bowl aside. Add squash, onion, garlic and red pepper flakes to skillet. Season with salt and pepper. Cook, stirring occasionally, until onion is translucent, about 8 to 10 minutes. Add broth. Bring the mixture to a boil, then reduce heat and simmer until squash is soft and liquid is reduced by half, about 15 to 20 minutes. In the meantime, bring a large pot of salted water to a boil and cook the pasta according to package directions, stirring occasionally, until al dente. Drain, reserving 1 cup cooking liquid. Once the squash mixture is done cooking, remove it from heat and let it cool slightly. Transfer the contents of the pan to a blender. Reserve the skillet. Purée the mixture until smooth (beware of hot steam escaping from the top of the blender), then season with salt and pepper to taste. Combine pasta, squash purée, and 1/4 cup cooking liquid in reserved skillet and cook over medium heat, tossing and adding more pasta cooking liquid as needed, until sauce coats pasta, about 2 minutes. Season with salt and pepper if necessary. Serve pasta topped with fried sage, more black pepper, shaved Parmesan/Pecorino, and smoked salt, if desired.


Announcing my new CD – "Love, Gratitude and Other Distractions". A collection of emotions, grooves & songs featuring a treasure trove of talented friends. Check out Love, Gratitude and Other Distractions by Will Lee on Amazon Music. Stream ad-free or purchase CD's and MP3s now on breenasmith.com Will Lee - Love Gratitude & Other Distractions - breenasmith.com Music.
Find a Will Lee - Love, Gratitude And Other Distractions first pressing or reissue. Complete your Will Lee collection. Shop Vinyl and CDs. Best known for his presence in Paul Shaffer's CBS Orchestra on the Late Show with David Letterman, Will Lee began his musical life as a drummer before. Find album reviews, stream songs, credits and award information for Love, Gratitude & Other Distractions - Will Lee on AllMusic.
1 Nov Bassist Will Lee has played almost everything with everybody as a first-call session musician and on your TV weeknights with David. Unsurprisingly, 'Love Gratitude and Other Distractions' is a star studded affair featuring Steve Lukather, Bob James, Billy Gibbons, Allen Toussaint and many. Listen to and buy Will Lee music on CD Baby. Download or buy the CD Love, Gratitude and Other Distractions by Will Lee on the independent record store by. Love, Gratitude and Other Distractions Will Lee; 10 videos; views; Updated yesterday. Play all. Share Will Lee Official "Get Out Of My Life Woman" Video. 22 Aug Twenty years after his solo debut, Will Lee has released his second album as a leader, entitled Love, Gratitude and Other Distractions.


Is Genetics Nature or Nurture?
When it comes to health, people often say, "Genetics is destiny." In other words, you were born pre-wired for the condition of your health today. Is that true? Well – yes and no.
When I was a lad in medicine, the great debate was over "Nature vs. Nurture." We were taught the prevailing wisdom that there were aspects of our lives that were determined by our genetic code and others that were a function of our environment. The debate concerned which factors fell into which category. Based on the medical knowledge we have today, it turns out that much of the intellectual and emotional energy of that debate was wasted. Now we know that a great deal of what we call "our genetic predisposition" is dramatically influenced by our environment. In other words, Nature is significantly affected by Nurture.


It is located in the city of Hyderbad. Built by the eminent architect Nawab Viqar-ul-Umra. Rare Italian Tudor styles are reflected in the palace.
It served as the royal guest house for the rulers. It is designed in the form of a scorpion. It has the largest manually operated organ in the world.
Witness the great architectural brilliance of the palace and get amazed by its splendor. Take prior permission for visiting this palace.
You will get to see the amazing piece of architecture of Falaknuma Palace in the city of Hyderabad. This city of the Nizams boasts of owning some of the most impressive edifices in the world. Falaknuma Palace in Hyderabad stands as a testimony to the glorious time of the Nizams. It is one of the finest pieces of architecture and is situated in Falaknuma. Engineered by the famous architect Nawab Vikar-ul-Umra, this palace connotes "Star of Heaven" in the Urdu language.
Falaknuma Palace, Hyderabad, located close to the Charminar served as the royal guest house for the rulers of Hyderbad. It shows a rare style of the Italian and Tudor architecture. Covering a total area of 9,39,712 square meters, the construction of the palace started on 3rd March, 1884. It took 9 long years to complete this architectural splendor. The exterior of the Falaknuma Palace is as impressive as the interior. Italian marbles were imported for the excellent works in the interior of the palace.
The palace looks somewhat like scorpion. The stings project out in the northern side of the palace. The arch gateways in the pyramidal fashion depict Neo Classical style of storeys. The staircase that leads to the various floors of the palace are made of authentic Italian marble. Marble figures and structures are another feature of the Falaknuma Palace. Portraits of the British Governor Generals adorn the interior walls of the palace. The library is equally impressive and is decorated with walnut carved wood. It houses some of the rarest manuscripts and books in the world.
There Falaknuma Palace in Hyderabad is counted as one of the most imposing monuments because of the large number of rooms built for various purposes. There are a total of 222 opulent rooms and 22 roomy halls. There are billiard room, card room smoking room, huge dining hall and others. The rooms are beautifully decorated with arches, upholstery, gilded works and state of the art furniture. The reception room is the major highlight of the palace with gilded decors and frescos.
The Venetian chandeliers are the major draw of the palace. There are 40 such chandeliers spread all through the Falaknuma Palace, Hyderabad. The colored glass of the windows also adds charm to the palace. The palace houses the largest manually operated organ in the world. The collections of jade articles in the palace are only one of its kinds in the world.
The palace at present is a part of the Taj Group and has been converted into a plush 5 star hotel. To get inside the Falaknuma Palace, you need to take prior permission. October to March is the ideal time to visit this palace.


Life Every Day: Never the Same Camp.
Since partnering with Poetice in 2010, I've seen so much change in how our own family lives and wrestles with God's heart for justice. One thing we've become free to enjoy is knowing this: we do not have to do it all.
Let that sink in. The weight of the world's brokenness is not ours to carry.
In joining with Poetice, we are able to invest in programs that promote real, lasting change. Progress that moves Zambian communities forward right now, and sets the stage for generational shifts toward health and wholeness.
And we aren't just working for physical healing. We are laboring toward wholeness. Complete healing for a nation, for communities, for families, for individual souls to be united with their Creator, free to worship the God who made them and sustains them. This is good news.
As we work together toward these goals, we are organically bound up in that work of righteousness, justice, and worship and can't help but be made right ourselves, too. Because we partner in this work together, bonds are formed across oceans, we're all set free, moving toward greater wholeness in our own hearts, families, communities. It's beautiful.
One of the most powerful things our Zambian staff does is organize and implement student camps. It's a time of community, joy, worship, education, and artistic opportunity. We don't simply do a little good, have a little fun, and send these young people on their way. We're not satisfied unless we see that these students have truly been impacted by their time at camp, never the same.
The local staff absolutely knocks it out of the park every time; passionate, equipped, bold, eloquent, and dedicated to seeing real change in these students' lives. I couldn't talk them up enough. This ministry is driven straight from the heart of God.
Students come to camp from many different communities. They receive truth, empowerment, prayer, essential HIV/AIDS education, good meals, an introduction to the arts, and time to just enjoy life.
We labor for these students to leave camp never the same, transformed. They then carry these things home with them, sharing them with their families, friends. We labor for them to return empowered to create change in their own lives, their own communities.
This is how Africa will be healed; one heart at a time, through the empowerment and building up of this next generation of leaders.
We don't need to speak every native tongue, to engage with every person individually, to carry the burden of saving a nation on our own backs. We partner with God in His work together, a community of like-minded passionate workers, bound together under one cause.
We each have something to bring to the table, and together God takes these gifts, multiplies them, and makes a feast.


Muhammad Ali was a fighter all his life, both in and out of the ring. He initially found fame as a champion boxer, celebrated for his unorthodox ring style and witty talk before, during, and after fights.
But Ali's charisma and commitment to social and political causes saw him transcend boxing to become one of the most famous people on the planet, at a time when black people lacked basic civil rights in America.
Discover how Ali became a modern icon through this epic look at the best quotes from The Greatest.


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F9 works by providing a library of Excel functions to Excel so that you can access GL information directly in real time from within Excel.
Each balance from each period in the total company history is available, along with useful values like account name, period name, company, and counts.
Using F9 means that you no longer have to struggle with unfamiliar report writers to format your GL data. Instead, you can use all the power of Excel to work with your data and get your business analysis or reports done in record time.


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Home / Politics / Niger Gov. Assures Payment Of All Pensioners, Inspects Verification Exercise (Photos)
Niger Gov. Assures Payment Of All Pensioners, Inspects Verification Exercise (Photos)
December 07, 2021 Politics
Following the decision of the Niger State government to carry out physical screening exercises of pensioners in the State in order to ensure pensioners are not shortchanged, Governor Abubakar Sani Bello has visited the venue of the ongoing exercise in Minna.
Governor Sani Bello who went round to observe the exercise, also interacted with some of the screening officials and pensioners who were seen in clusters according to their local government area of residence.
Speaking to journalists shortly after monitoring the exercise, Governor Sani Bello explained that it is meant to cleanse the system from pension scams and other financial irregularities stressing that it was not to cause any hardship to the pensioners but to sanitize the system.
"The whole essence of this screening is not to inconvenience anyone, but I have received reports of many innocent pensioners that have not been receiving their pension.
"We have also received reports of a lot of fraud when it comes to pensions. I have always known that there are some kind of sharp practices when it comes to pension payment", he said.
He urged the pensioners to be patient with the exercise as he is optimistic it will achieve the desired objectives.
The Governor directed that payment should be made to those that have been cleared and suggested to the screening committee to follow some of the pensioners who are sick or very weak to withstand the rigor of the exercise to their houses to get them screened.
Some of the pensioners interviewed applauded the government for the exercise, pointing out that it will help uncover lots of sharp practices and block some leakages.
Niger Gov. Assures Payment Of All Pensioners, Inspects Verification Exercise (Photos) Reviewed by Kosisochukwu on December 07, 2021 Rating: 5


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Australobittacus is een geslacht van schorpioenvliegen (Mecoptera) uit de familie hangvliegen (Bittacidae).

Soorten
Australobittacus omvat de volgende soorten:
Australobittacus anomalus Riek , 1954

Hangvliegen