text:
How to Fix the Utah Offense Next Season
By Alex Stark@starkaw23 Dec 30, 2015, 10:04pm MST
Share All sharing options for: How to Fix the Utah Offense Next Season
Kirby Lee-USA TODAY Sports
Utah's offense has struggled since joining the Pac-12. Utah has never finished better than 11th in the Pac-12 in total offense. Having a great offense is certainly not necessary to win the conference. Stanford has won the Pac-12 in three of the last five seasons, and they never ranked better than eighth in total offense in any of those seasons. This article will cover the problems that have plagued the Utah offense and some potential fixes.
Utah is one of the most physical teams in the conference. They are the only team in the conference that can push around Stanford. With this in mind, should Utah run a pro-style offense? No. In 2011, Utah ran a pro-style offense under former offensive coordinator Norm Chow. This was by far Utah's worst offense in the Pac-12. They averaged only 310.9 yards per game (which was dead last in the Pac-12 and No. 109 in the nation). Under Brian Johnson in 2012, Utah ran a multiple offense which included a lot of I-formation power running, and they finished 11th in the Pac-12 and 108th in the nation in total offense. I believe for the Utes the future is in the spread offense for multiple reasons. One big one being that they have recruited primarily for a spread offense. Now just because Utah runs a spread offense does not mean they should abandon physical running. They have the reputation for physicality for a reason, and they should maintain that philosophy. However, power running alone is not enough in a league like the Pac-12 with many high-powered offenses.
Before we can talk about fixing Utah's offense, we first need to discuss the problems that are causing the offense to struggle. Injuries certainly have plagued the Utah offense. Starting quarterbacks Jordan Wynn, Travis Wilson, and Kendal Thompson all suffered season-ending in their Utah careers. Utah's two best running backs in the Pac-12, John White IV and Devontae Booker, both missed time due to injuries. Utah also has suffered numerous injuries at wide receiver. Injuries though are part of football, so while they have played a part in Utah's offensive woes, they are certainly not the only issue to blame. The three biggest issues for the Utah offense are in no order: play calling, quarterback play, and wide receiver play.
Utah has changed offensive coordinators every season since 2008, meaning schemes and terminology have changed as well. Most of the OCs ran some variation of a spread offense, with the exceptions being Chow and Johnson in 2011 and 2012 running a pro-style and a multiple offense respectively. In every season in the Pac-12 (except 2013), Utah was near the top of the conference in run-to-pass ratio.
The goal of a spread offense is to spread out a defense, hence the name. Utah however does not achieve this. The Utes run the ball so frequently inside the tackles that the defense can stack the box. Utah has also failed to produce an effective passing attack, further allowing the defense to key in on the running game. The spread offense typically uses smaller, faster players at the H and Y positions. In Utah's spread offense, they keep a tight end at the Y position, but they replace the H back (or full back) with a slot receiver on most plays. Stanford can get away with running at a stacked box because they frequently has formations with seven or even eight offensive linemen on the field. If Utah is committed to running the spread offense, they need to come up with create ways force the defense to respect the perimeter of the field, thereby spreading out the defense. Utah was a run-first team in 2015, but they were 10th in the Pac-12 in yards per carry, ahead of only Colorado and WSU. Utah used only one running back primarily (with the exception being in 2013): John White IV in 2011 and 2012 and Devontae Booker in 2014 and 2015. Because Utah relied too heavily on just one running back to carry the load, both White IV and Booker got hurt in their second season as the feature back (where no such running back injuries occurred in 2013). This run-first approach has caused speedy playmakers on the perimeter to be under utilized in favor of the power rushing attack.
Once Utah lost Booker, the offense began to really struggle. Utah managed their three worst offensive games of the season without Booker. Utah's 3.13 yards per play against BYU was their worst total as a Pac-12 team, and their 197 total yards in that game was the second lowest total since joining the Pac-12 (ahead of only the 188 total yards they gained at Washington in 2012). The Utah passing attack could not step up in Booker's absence. Quarterback Travis Wilson had his three lowest passing totals in Utah's final three games, ending the season with a 71-yard outing against BYU. Booker is now off to the NFL, so the offense will need to figure out other ways to move the ball in 2016.
It seems like the offensive coordinators for the Utes call overly conservative game plans except against overmatched opponents (like FCS teams) or in situations where they have nothing to lose by being aggressive (like against Oregon this year or in games where the Utes are well behind). Utah also often fails to put teams away after getting a lead. This falls on the play calling. Utah's strengths in the Pac-12 have always been defense, special teams, and running the football. Utah's MO the last few years has been to be conservative on offense and allow the excellent defense and special teams to win the field position battle. This has worked the last two seasons when Utah has had the back-to-back Ray Guy Award winner at punter (Tom Hackett), an excellent kicker in Andy Phillips, dynamic return men (like Reggie Dunn, Kaelin Clay, and Britain Covey), and a defense full of playmakers, who could generate sacks and/or takeaways. This strategy will not work as well moving forward however because Utah loses a lot on defense in addition to Hackett. Utah will need to be more aggressive on offense in 2016 because they will not be able to win the field position battle as effectively.
Poor play calling has been amplified by poor play from both wide receivers and quarterbacks. Outside of Dres Anderson's 1,000 yard receiving season in 2013, Utah's wide receivers have struggled in the Pac-12. The Utes have primarily had two types of wide receivers in the Pac-12. The wide receivers have either been faster wide receivers with poor hands (and are often smaller) or wide receivers who can catch but are not fast enough to create separation consistently (and are often bigger). This falls largely on coaches for failing to effectively recruit and develop wide receivers. Utah has not landed a four-star wide receiver (based on the 247Sports Composite ranking) since joining the Pac-12. Utah has had plenty of tall wide receivers who have shown the ability to out-jump defenders for the football despite lacking the speed to create separation. Certain routes either do not require much separation because the rely more on jump balls (like fades). Combination routes can also be used to create space for wide receivers as well. Utah failed to call these types of plays enough to utilize the talent they have had at wide receiver. Utah did not retain wide receiver coach Taylor Stubblefield for next season, letting him go after two seasons. The new wide receiver coach will have plenty of experienced wide receivers to work with but will be tasked with helping them improve at catching the football and/or creating separation.
Travis Wilson started by far the most games at quarterback for Utah in the Pac-12. He had his ups and downs in his Utah career. This was not completely his fault. The revolving door at OC and wide receiver drops were not his fault. He however had his flaws as well. He was not the best at reading the defense and did not throw with anticipation. He also struggled with inaccuracy. These issues magnified the wide receiver issues that were compounded by poor play calling.
Now that we have broken down some of the issues contributing to Utah's offensive woes, how does the team go about fixing these issues? First off, the passing game needs to improve. Utah can clearly force a defense to respect the running game, which can help the passing game. Utah did not run enough play action last season, and it seemed like most of the time when the Utes would utilize play action, it was on an obvious passing down (like the last offensive play against UCLA). Creatively mixing in play action is one way to keep a defense honest.
Utah seemed to have very basic routes for their wide receivers last season. This makes it easier for a defense in pass coverage. Running a variety of different routes and combination routes can help wide receivers create more separation, yielding easier throws for a quarterback. When a defense brings extra defenders like safeties into the box to stop the run, vertical routes can be very effective.
Another way to keep the defense from stacking the box is using screens. Utah had success last season throwing bubble screens to Covey and Bubba Poole. One effective combination route is to run a bubble screen and a slant route, which will often result in space for one of the two receivers. There are other types of screens Utah could run more as well like middle screens, slip screens, and slot screens. One play, while not technically a screen, that Utah used to run all the time was the Utah pass. It is an overhand shovel option pass. You can see this play run below with Alex Smith at quarterback.
Along the lines of the shovel option, there are other rushing plays that can stretch the defense to the sideline. Plays like jet sweeps, speed options, toss plays, etc. all challenge the defense on the perimeter, preventing the defense from stacking the box. Utah will have players like Troy McCormick, Kyle Fulks, and Kenric Young among others who all have the speed to get around the edge of the defense. Running five to 10 perimeter running plays a game will help keep the opposing defense honest.
A core part of Utah's offense has been the read option. This does incorporate some perimeter running by either the quarterback or running back, but there is a modern variation of the triple option that really forces the defense to respect the perimeter. In the triple option, the first read is the defensive end. If he stays outside, the quarterback hands off to the dive man, and if he crashes in, the quarterback keeps the ball. The second read is the pitch man, and the quarterback either keeps the ball or pitches it depending on who the pitch man takes. The modern twist on this is instead of pitching, the third option is a screen pass to the sideline. Many teams have started to add this type of play to their spread offense because it makes the read option even more difficult to stop. An example of the play run by NIU can be seen below.
Utah will have a lot of new faces at the skill positions in the offense next season. Utah will not have a quarterback with any starting experience on the roster. Booker is gone at running back, and he was by far Utah's best offensive weapon for two seasons. They also lose three wide receivers (Covey, Poole, and Kenneth Scott). Utah will be relying on unproven players at key positions on offense. The quarterback battle was broken down well here. Utah will likely rely on Joe Williams and Troy McCormick at running back. There are a lot of upperclassmen at wide receiver for Utah, but none are proven commodities. Utah will need guys like Tim Patrick, Delshawn McClellon, Kenric Young, Kyle Fulks, Tyrone Smith, or Raelon Singleton to step up to give the new Utah quarterback someone to throw the ball to.


Douglas Coupland will host what is being called an "interactive presentation" at the Waldorf Hotel in East Vancouver May 26.
The author/artist will speak on "the Global Village and YouTube", according to the press release, and expand on the idea that the video website is "the ultimate manifestation of the global village" as well as of our collective consciousness.
No doubt Coupland will also be drawing on ideas from the Canadian Dean of All Media, Marshal McLuhan; one of the noted Vancouver author's recent books was a biography of McLuhan called You Know Nothing of My Work (titled after a quote by McLuhan in the Woody Allen movie Annie Hall).
This entry was posted in Books and tagged Douglas Coupland, Vancouver authors, Vancouver events. Bookmark the permalink.


Kass Being Difficult Again – Fight Aging!
CNN is covering comments by President Bush's bioethics council chairman on stem cell research at Stanford. It seems Kass just can't abide seeing vital research on cancer and other diseases forging ahead.


WATERLOO, ON—(Marketwired – February 27, 2018) – D2L, the global learning technology leader, announces that Brewton–Parker College, the only accredited four–year Christian college south of Macon, GA, and north of Jacksonville, FL, selected its Brightspace Learning Management System (LMS) to deliver a modern learning environment to both students and faculty.
"As a rural school, we must have an LMS to effectively reach more students and provide them with an educational experience catered to individual learning needs and styles," said Lynn Addison, Chair, Division of Online, Developmental & External Programs, Brewton–Parker College.
"Brightspace represents a considerable step forward for us to deliver the tools we need to bring a higher level of education and engagement for all of our students ¾ on campus or online," said Jonathan Cowart, Director of Online, Brewton–Parker College.
To achieve its learning objectives, the leaders of Brewton–Parker College needed to replace its legacy LMS. The review process, which included Canvas and others, solicited feedback from faculty and staff through focus groups and demos. The near unanimous consensus was that Brightspace is the easiest and most intuitive LMS, with a robust set of features and functionality that will allow faculty to modernize how they teach, monitor and engage with students. The platform's ability to integrate with third–party tools and responsive interface designed to work across any device were also critical components in their decision.
Brightspace is a cloud–based learning platform that makes online and blended learning easy, flexible, and smart. Brightspace is a quantum leap beyond traditional Learning Management System (LMS) – it is easy to drag–and–drop content to create engaging courses, supports all mobile devices, has industry–leading uptime, and is accessible for all learners. Plus, Brightspace enables the future of learning with a gaming engine, adaptive learning, video management, intelligent agents, templated interactives for course design, full support for outcomes or competency–based learning, and actionable learning analytics.
D2L's Brightspace was named the #1 LMS in Higher Ed by Ovum Research and #1 in Adaptive Learning by eLearning Magazine. In addition, Aragon Research included D2L in its highly coveted Hot Vendors In Learning list.
The D2L family of companies includes D2L Corporation, D2L Ltd, D2L Australia Pty Ltd, D2L Europe Ltd, D2L Asia Pte Ltd and D2L Brasil Soluções de Tecnologia para Educação Ltda. All D2L marks are trademarks of D2L Corporation. Please visit D2L.com/trademarks for a list of D2L marks.


Converse with us, find out about our weekly arrivals of lululemon and all the great ways to sweat, new classes, great instructors, our latest groovy moves, our new jewelry lines by local artists, our new beautiful paintings and more....ask us questions..... we'd love to hear from you. Share your pics with us on instagram @BMCTbay of your sassy yoga moves !!


text:
<?php
namespace Inventory\Application\Specification\Doctrine;

/**
 *
 * @author Nguyen Mau Tri - ngmautri@gmail.com
 *
 */
class OnhandQuantitySpecification extends DoctrineSpecification
{

    /**
     *
     * {@inheritdoc}
     * @see \Application\Domain\Shared\Specification\AbstractSpecification::isSatisfiedBy()
     */
    public function isSatisfiedBy($subject)
    {
        $wareHouseId = null;
        if (isset($subject["warehouseId"])) {
            $wareHouseId = $subject["warehouseId"];
        }

        $itemId = null;
        if (isset($subject["itemId"])) {
            $itemId = $subject["itemId"];
        }

        $movementDate = null;
        if (isset($subject["movementDate"])) {
            $movementDate = $subject["movementDate"];
        }

        $docQuantity = null;
        if (isset($subject["docQuantity"])) {
            $docQuantity = $subject["docQuantity"];
        }

        if ($this->doctrineEM == null || $itemId == null || $wareHouseId == null || $movementDate == null || $docQuantity == null) {
            return false;
        }

        $onhand = 0;

        $sql = "
SELECT
     SUM(nmt_inventory_fifo_layer.onhand_quantity) AS current_onhand
FROM nmt_inventory_fifo_layer
WHERE 1 %s
GROUP BY nmt_inventory_fifo_layer.item_id, nmt_inventory_fifo_layer.warehouse_id
";

        $sql1 = sprintf("AND nmt_inventory_fifo_layer.posting_date <='%s'
AND nmt_inventory_fifo_layer.item_id = %s
AND nmt_inventory_fifo_layer.warehouse_id = %s
AND nmt_inventory_fifo_layer.is_closed=0", $movementDate, $itemId, $wareHouseId);

        $sql = sprintf($sql, $sql1);
        $stmt = $this->getDoctrineEM()
            ->getConnection()
            ->prepare($sql);
        $stmt->execute();
        $results = $stmt->fetchAll();

        if (count($results) == 1)
            $onhand = $results[0]['current_onhand'];

        if ($onhand < $docQuantity || $onhand == 0)
            return false;

        return true;
    }
}

redpajama_set_name: RedPajamaGithub


1. About God: The powerful and frightening demoniac (Mark 5:6), who could not be bound, runs at Jesus only to fall on his knees before him to beg for mercy. Jesus must have been an impressive figure of both power and compassion.
3. DWIS: "tell them how The Lord has done for you." Mk 5:19-20. Rather than just share about church events or give driving directions to church, I will tell someone what Jesus has done for me. For he has delivered me from an empty way of life where I tried in vain to conjure up purpose, peace, significance, and character. Jesus gave me all this AND a family to cherish, friends in abundance, purity from the inside out, and hope on an epic eternal scale.


text:
La batalla de Aribanaches (o Aribanache) fue un enfrentamiento militar librado el 15 de noviembre de 1810, en el contexto de las primeras etapas de la Guerra de Independencia de Venezuela, durante la Campaña de Coro, entre las fuerzas expedicionarias leales a la Junta Suprema de Caracas y las tropas realistas fieles a la Regencia de España.

Historia
El día 14, el coronel patriota Luis Santinelli venció a los realistas en Pedregal, quienes se retiraron en la noche y fueron perseguidos por los vencedores. En tanto, el capitán general Fernando Miyares salió de Maracaibo con una columna, el 12 de noviembre estaba en Purureche y dos días después intentaba detener a Santinelli en Pedregal.

El 15 de noviembre, la primera división atacaron a los realistas en Paso del Puerto, a dos leguas de Urumaco, en un lugar llamado Aribanaches. Se sabe que participaron el batallón Aragua y la artillería. Ahí el coronel Santinelli se enfrentó al comandante José Miralles, hijo del capitán general, quien estaba bloqueaba el camino y tenía apoyo de cañones, además de bosques en ambos costados de la vía. Los patriotas atacaron y desalojaron a sus enemigos después de dos horas de lucha. Las bajas monárquicas fueron de 22 muertos y muchos heridos, mutilados y dispersos. Fueron capturados el botiquín, 44 kilogramos de proyectiles, la artillería (quizás dos piezas) y algunos fusiles. Las bajas patriotas fueron 2 muertos y 3 heridos, además de 3 caballos heridos.

Al día siguiente, el marqués entró con la reserva y el 17 de noviembre la vanguardia se apoderó de Urumaco y Mitare. En tanto, los vencidos se retiraron a Casicure y las tropas realistas en Mitare, dos compañías de indios flecheros, se retiraron a Coro. El día 18 la columna de vanguardia, por la vía de Sabaneta, se había situado en Agua Clara. Encontrándose en Pedregal el marqués recibió informes de que era numerosa la milicia reunida en Coro. El marqués, desde Pedregal, dirigió una proclama a los vecinos del distrito capitular, la cual fue reproducida por la prensa caraqueña de entonces.

Se le considera el «primer combate de América en el ciclo de la Independencia». También se ha dicho: «¡Fue en el sitio de Aribanaches donde se vertió por la vez primera la sangre venezolana!».

Véase también

 Campaña de Coro

Referencias

Bibliografía

Enlaces externos
 Héctor Bencomo Barrios. Aribanache, combate de. Diccionario histórico de Venezuela.

Aribanaches
Venezuela en 1810
Historia de Falcón

redpajama_set_name: RedPajamaWikipedia


text:
Category: Alex Mack Jersey
Eight appearances under his belt paralympic season Kirk's stat
Open to the public it will air live on NFL Network.He will oversee all U.S.It was the greatest intermission entertainment that fans could ask for as the players immediately ripped off their shirts and had themselves a great time cruising around the rink.is leaving the company at the end of the month after for 15 years.
He played two road games against his former team last season, but the Toronto-New York matchup at Nassau Coliseum on Wednesday will mark the first time he'll face the Islanders as Maple Leafs captain.Since the release of the first edition in 1988, the franchise has topped $4 billion in sales, according to industry analysts.He also had four hits and two PIM against his former squad.Alexa turns up the volume on a powerful orchestral piece, which converts the water into a Las Vegas-style fountain, which sends the two women flying out of the water.However, knowing all the new pieces that will need to fit together up front, acquiring players with NFL experience should help to smooth the transition.
According to NTT, Ultra Reality Viewing Authentic Kids Alex Mack Jersey is its Limited Mens Andrew Hammond Jersey real-time super high-definition surround video synthesis technology that combines multiple 4K camera images into a super-wide image – such as 12K in real-time – and transmits them synchronously to remote locations.The talented teen now has 19 goals and 39 points in 64 games.Williams claimed Courtyard's Suite Stadium honor by acquiring the highest number of judge and fan votes after a series of social media challenges completed on Twitter and Instagram.The top two U.S.
�?Kellogg's said its Pop-Tarts brand would appear on Super Bowl broadcasting for the first time with a 30-second spot to air on Fox during Super Bowl LIV on Feb.�?John Shea, president-marketing, Americas for marketing and talent management agency Octagon since 2016, has been named global president-marketing and events, Octagon Worldwide.Olympic & Paralympic Committee said that the 124th Boston Marathon, scheduled for April 20, will serve as the 2020 U.S.
I'm a nine-time All-Star, he begins.The ESPNEWS telecast will also feature its own commentator team, including play-by-play voice Jason Benetti and analyst Eduardo Perez, according to ESPN.said in a statement.The 23-year-old winger potted one goal in 11 appearances with the big club last season.
Nick Foles took http://www.atlantafalconslockershop.com/alex-mack-jersey-wholesale over for the injured Carson Wentz and put up some improbable numbers under center.
White has battled a lack of hype since last season, being given no recognition at multiple honors including as a Pro Bowler, or as recently as being left off the list of the top-10 second year players put together by Nate Burleson.Holmes birdied all but one of the par 5s at Torrey Pines and escaped with bogey on his one big miss Saturday, giving him a 4-under 68 to join Harris English at the top of a crowded leaderboard in the Farmers Insurance Open.�?Kate Johnson vp-global sponsorship marketing for Visa since 2013 and a silver medal winner in rowing in the 2004 http://www.officialsbuffalosabrestore.com/Adidas-Andrew-Hammond-Jersey Athens Summer Olympics, is leaving the company to join Google to head a new division focusing on global partnerships in sports.�?John Shea, president-marketing, Americas for marketing and talent management agency Octagon since 2016, has been named global president-marketing and events, Octagon Worldwide.
To see how many people were engaging literally 24 hours a day for 17 days.Now, armed with stats and sale figures, Cohn said, With Tim Tebow, we have the ability to talk to new consumers.NYSJ: PM: We have had a couple of successful years.A launch TV spot is scheduled to break on TNT on Feb.

redpajama_set_name: RedPajamaCommonCrawl


I first saw Roger Nelson perform his play The Man from Aldersgate, about John Wesley, the summer before I moved to New York. It was at a Christians in Theatre Arts Conference in Vancouver, BC. I was inspired on a number of levels: It confirmed my leadings to move to NYC, confirmed that Christians could work in the arts professionally, and specifically inspired me to work more on one-man plays.
Not long after that, Irv Brendlinger, now a professor at my alma mater, George Fox University, hired me for one of my first performances of A Clear Leading. Irv was a great fan of the subject of my play, John Woolman, and his enthusiasm was a real catalyst for getting me to the next level in touring the show.
Now that I'm getting A Clear Leading back on its feet, I was delighted to find that Irv has come out with book about John Wesley!
It's fascinating to me to see all of God's connections out there in the world!


Urea formaldehyde resin (UFR) is non-transparent thermosetting synthetic resin derived from a chemical mixture of urea and formaldehyde. It is mainly consumed as an adhesive for bonding construction and building materials. Globally, development of efficient and advanced technology, rising demand for good quality and economically viable adhesives and resins, flourishing automotive industry, growing electrical appliances, and advantageous properties of urea formaldehyde such as, high tensile strength, flexural modulus and scratch resistant are the prime growth drivers of the urea formaldehyde market.
Three different polymer composites of epoxy resins are being synthesized which are modified by urea formaldehyde .Some of its end use applications are plywood, medium density fiberboard, and coatings. Paper, textile, corduroy, rayon are among various industries that requires urea formaldehyde formed adhesives in their operations. In addition, increase in adoption of urea formaldehyde for application in new industrial verticals, and emerging economies such as China, India and others, will create new opportunities for the urea formaldehyde market.
Wood flour and thermoplastic‐modified urea‐formaldehyde (UF) suspensions are blended to form a wood composite which can sustain impacts better than other similar composites. Wooden furniture market on a global forum is expected to grow at a CAGR of around 5% during 2018-2022. However, volatile prices and availability of raw materials, availability of substitute compounds, and stringent government environment regulations are the key restraints for the urea formaldehyde market.
Geographically, North America dominated the urea formaldehyde market, Asia Pacific is projected to have the fastest growth, owing to a rapidly increasing automobile industry, rise in industrial sector, and growing consumption of electrical appliances in developing nations such as China, and India in this region. Among all the applications, particle board segment has the highest market share in the urea formaldehyde market. Home appliances and electrical appliances are the market leaders among all end-user industries of urea formaldehyde, owing to rising need of adhesives. The report also aid to highlight market size in terms of volume and value.
This report identifies the urea formaldehyde market size for the years 2014-2016, and forecast of the same till the year 2022. It also highlights in-depth analysis on market drivers, market trends, restraints, growth indicators, challenges, and other key aspects with respect to the urea formaldehyde market.


text:
//
//  MUJSONSerializer.h
//  moxuyou_Base
//
//  Created by moxuyou on 2016/12/13.
//  Copyright © 2016年 moxuyou. All rights reserved.
//

#import <Foundation/Foundation.h>
#import "AFNetworking.h"
#import "NSObject+MUJSONMapping.h"

/**
 *  MUResponseSerializer is subclass of AFJSONResponseSerializer which automatically serialize
 *  response foundation objects to your custom model objects.
 *  It also works with NSManagedObjects
 */
@interface MUResponseSerializer : AFJSONResponseSerializer <AFURLResponseSerialization>

/**
 *  Tells MUJSONResponseSerializer which class is top level object.
 *  In case of array of ojects, the serializer assumed that all objects in the array are the same class
 */
@property (nonatomic) Class responseObjectClass;

/**
 * Designated initializer, which sets responseObjectClass property
 *
 * param Class responseObjectClass
 * return MUResponseSerializer instance
 */
- (instancetype)initWithResponseClass:(Class)aClass;

@end


Only 2 left. I will restock these if I can find a new supplier. Dust mites are nasty little critters that can cause a lot of discomfort for people who are sensitive or overexposed to them. Dust mites like a moister environment and like their name suggests, they like dust. Barrier covers protect your mattresses and pillows from these little critters entering them and laying their eggs in your bedding. Natural wool and natural rubber seem to also act to deter dust mites (which are about 100 microns) naturally.
Our barrier cloth is a high 440 thread count SKAL certified organic cotton fabric that is then heat pressed to tighten the fibers to a 6 micron opening - recommended to protect against dust mites debris.. We do not contaminate our organic cotton by adding any chemicals or urethanes. Chemical-Free. There is no other company on this continent that can provide an organic barrier cover that is completely chemical-free. In addition, we do not dye our fabrics to make them look richer.
Our pillow barrier covers feature a nice tight tooth plastic zipper (PVC-Free) to keep the little critters away from your head. Brass zippers have a lot of open space in between teeth and are not recommended for barrier covers.


text:
Q: Deserialise JSON String to Object with AngularJS using Generate Ionic I am following this AngularJS Tutorial.
I am successfully able to display a data model array list in the browser (Chrome 37.0.2062.94) when instantiated using object literal notation, where $scope.sentences is of type "Object".
Controller: (extract)
'use strict';
angular.module('YeomanIonic.controllers', [])
.controller('MapCtrl', ['$scope', '$ionicLoading', '$http', function($scope, $ionicLoading, $http) {
$scope.sentences = [
  {"name": "Hello",
   "snippet": "1"
  },
  {"name": "Goodbye",
   "snippet": "2"
  }
];
}]);

View (extract):

                {{sentence.name}}

{{sentence.snippet}}

But I get problems when I instead store this array of hashes in a JSON file (i.e. app/data/sentences.json), as follows:
sentences.JSON:
[
  {"name": "Hello",
   "snippet": "1"
  },
  {"name": "Goodbye",
   "snippet": "2"
  }
];

I attempt to use the AngularJS $http service to perform a HTTP GET request to fetch this JSON data. The tutorial mentions that AngularJS detects and parses the JSON response automatically and that the $http service returns a promise object with a success method. So I assumed that the following code would work correctly such that $scope.sentences would be of type "Object", however it informs me that it is of type "String".
  $http({
    method: 'GET',
    url: 'data/sentences.json'
  }).
    success(function(data, status, headers, config) {
      console.log("HTTP Request - Success");
      $scope.sentences = data;
      console.log(typeof($scope.sentences));
    }).
    error(function(data, status, headers, config) {
      console.log("HTTP Request - Error");
    });

So I attempted to assign it with this following code instead, which gives the following error:
$scope.sentences = angular.fromJson(data);

SyntaxError: Unexpected token ;
    at Object.parse (native)
    at Object.fromJson (http://127.0.0.1:9000/bower_components/angular/angular.js:1139:14)
    at http://127.0.0.1:9000/scripts/controllers.js:34:59
    at http://127.0.0.1:9000/bower_components/angular/angular.js:8105:11
    at wrappedCallback (http://127.0.0.1:9000/bower_components/angular/angular.js:11561:81)
    at wrappedCallback (http://127.0.0.1:9000/bower_components/angular/angular.js:11561:81)
    at http://127.0.0.1:9000/bower_components/angular/angular.js:11647:26
    at Scope.$eval (http://127.0.0.1:9000/bower_components/angular/angular.js:12673:28)
    at Scope.$digest (http://127.0.0.1:9000/bower_components/angular/angular.js:12485:31)
    at Scope.$apply (http://127.0.0.1:9000/bower_components/angular/angular.js:12777:24) angular.js:10061

I try the below alternative with quotations included, which gives the following error (which is getting confused with the letter 'd' in the word 'data') :
$scope.sentences = angular.fromJson('data');

SyntaxError: Unexpected token d
    at Object.parse (native)
    at Object.fromJson (http://127.0.0.1:9000/bower_components/angular/angular.js:1139:14)
    at http://127.0.0.1:9000/scripts/controllers.js:34:59
    at http://127.0.0.1:9000/bower_components/angular/angular.js:8105:11
    at wrappedCallback (http://127.0.0.1:9000/bower_components/angular/angular.js:11561:81)
    at wrappedCallback (http://127.0.0.1:9000/bower_components/angular/angular.js:11561:81)
    at http://127.0.0.1:9000/bower_components/angular/angular.js:11647:26
    at Scope.$eval (http://127.0.0.1:9000/bower_components/angular/angular.js:12673:28)
    at Scope.$digest (http://127.0.0.1:9000/bower_components/angular/angular.js:12485:31)
    at Scope.$apply (http://127.0.0.1:9000/bower_components/angular/angular.js:12777:24) angular.js:10061

I try this third alternative, which gives the same as the previous error:
$scope.sentences = window.JSON.parse('data');

I try a fourth alternative, which also gives the same as the previous error:
$scope.sentences = JSON.parse('data');

With little hope left I came across this [lifesaver post] (https://stackoverflow.com/a/6487190/3208553) that mentioned using eval('data'), but which also mentions that it presents a security risk, but I gave it a shot with:
$scope.sentences = eval(data);

And this works!! It successfully grabs and displays the data from the JSON file as a list in the browser. Note that when I check what it assigns with console.log(eval(data)); it gives me [object Object],[object Object],[object Object],[object Object]
But I can't celebrate because I don't understand why the other alternatives that I tried didn't work...
So my questions to the community are:

*

*Why doesn't the AngularJS $http service detect and parses the JSON response automatically and return it as an Object (instead of a String)?

*Why doesn't the AngularJS fromJSON deserialize the JSON string without an error? (which appears to simply perform JSON.parse('') according to its Source Code)

*Is my JSON encoding competent and are my inputs incorrectly validated in this simple example? Is this why only the unsafe 'eval' method works for me (with its associated security risks)?

FYI, Here is the latest commit to my Ionic app associated with this post on GitHub

A: I fixed this bug after finding a missing comma in my JSON file.

redpajama_set_name: RedPajamaStackExchange


text:
Alternative Therapeutic Method for Type Two Diabetes: Whole Body Vibration Therapy: A Mini-Review
Erika L Simmerman1, Xu Qin1,2, Henrik O Berdel1,3, Mahmood S Mozaffari1, Babak Baban1, Jack C Yu1,4
1Department of Oral Biology, Georgia Regents University, Building CL2140, 1120 15th St, Augusta, GA, USA
2Tongue Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Stomatology, Wuhan, Hubei, China
3Palmeto Health/University of South Carolina School of Medicine, Columbia, SC, USA
4Department of Surgery, Division of Plastic Surgery, Georgia Regents University, Building HB-5040, 1120 15th, Augusta, GA, USA
Babak Baban
Department of Oral Biology
Georgia Regents University
Building CL2140, 1120 15th St, Augusta, GA, USA
Phone +706-721-2032
Fax +706-721-6252
Received November 14th, 2015 - Accepted January 6th, 2016
Context As the prevalence of obesity and diabetes continues to increase there is a need for new interventions to control this epidemic. Multiple alternative treatment methods exist for type 2 diabetes mellitus such as acupuncture, bariatric surgery, yoga, aromatherapy, herbal remedies, etc. Whole Body Vibration is a relatively new area of interest recently utilized as an adjunctive therapy in type 2 diabetes mellitus, representing a potentially new and novel treatment for type 2 diabetes mellitus. Objective The primary objective of this study was to summarize current literature regarding the effects of whole body vibration on type 2 diabetes mellitus. This review details the effect of whole body vibration on areas of high clinical impact in the treatment of type 2 diabetes mellitus such as glycemic control, body composition, renal function, inflammatory indices, peripheral neuropathy, and wound healing. Methods Reviewers independently screened abstracts and full texts in journal articles and books to extract data from multiple studies and literature to compile a current review on the topic of whole body vibration and diabetes mellitus. Results Current literature in murine and human models reported an overall improvement in glycemic control, renal function, inflammatory indices, and peripheral neuropathy following whole body vibration therapy. Whole body vibration effect on body mass composition is controversial with inconsistent reports of the effect on lean mass, bone density, and fat mass. Conclusions Whole body vibration has demonstrated significant promise in improving multiple systems related to the sequela of type 2 diabetes mellitus, thereby suggesting a new and novel treatment modification in this patient population. Subsequent studies are needed to further analyze the effect of whole body vibration on type 2 diabetes mellitus.
Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Hemoglobin A, Glycosylated; Wound Healing
T2DM type 2 diabetes mellitus; WBV whole body vibration;
Diabetes is the fifth leading cause of death in the US, and according to the National Diabetes Statistics Report in 2014 approximately 29 million Americans are living with diabetes mellitus with the majority being type 2 diabetes mellitus (T2DM) [1]. It is reported that every 10 seconds a person dies worldwide secondary to a diabetesrelated pathology [2]. The prevalence of childhood obesity continues to rise dramatically, going hand in hand with the increased incidence of T2DM. According to recent studies, 25% of children and adolescents are overweight or obese [3]. The prevalence of T2DM in adolescents 12 to 19 years rose from 9% in 1999/2000 to a staggering 23% in 2007/2008 according to the 2008 National Health and Nutrition Examination Survey (NHANES) [4, 5]. Excess caloric intake combined with decreased physical activity and energy expenditure as a result of a more sedentary lifestyle has led to this inevitable increase in T2DM and obesity. These lifestyle trends have resulted in a staggering rise of Lifestyle-Related Chronic Diseases including diabetes, obesity, hypertension, and cardiovascular disease [6]. With the increasing prevalence of T2DM, there is increasing economical burden worldwide as a result of secondary health complications [2].
Central obesity, impaired insulin secretion from pancreatic B-cells, and decreased insulin sensitivity of peripheral tissues contribute to insulin resistance which results in hyperglycemia and ultimately T2DM as a result of a progressive imbalance in glucose homeostasis. Recent studies have reported pancreatic beta cells as regulators of rhythmic transcription genes controlling insulin secretion, revealing an essential role of the circadian timing system in diabetes [7, 8]. Excess visceral adipose tissue is independently associated with the development of diabetes secondary to increased insulin resistance [4, 9]. Impaired insulin-induced signal transduction results in peripheral insulin resistance via impairment of membrane translocation of glucose transporters [1, 10]. Pharmacologic treatment has focused on improving tissue sensitivity, increasing insulin levels, and reducing carbohydrate absorption from the gastrointestinal tract [2]. In short, the pathogenesis behind T2DM is multifactorial and requires evolving treatment modalities to improve management of this complex disease process.
Nutrition and exercise are the number one recommendations for treatment of T2DM. With regular exercise there is an increase in energy expenditure with the expectation of decreasing peripheral adipose tissue. With resistance training and aerobic exercise there is generally a reduction in HbA1c, fasting glucose, hyperlipidemia, and hypertension [11]. Exercise may also improve glycemic control in T2DM due to anti-inflammatory properties as demonstrated in animal models [1, 12-14]. Although this approach is the most recommended, there is low compliance long term with strenuous and time-consuming exercise regimens. Thus, there is the need for developing new and novel treatment strategies. Like exercise, whole body vibration (WBV) exerts mechanical stresses on the skeleton, which could potentially indicate a novel exercise modification. It may allow the health benefits of exercise without the intensity and duration of standard sustained exercise programs. This review will detail specific findings involving the effects of standard high frequency, low-amplitude WBV on factors related to T2DM such as body mass composition, glycemic control, renal function, inflammation, peripheral neuropathy, and wound healing.
WHAT IS WHOLE BODY VIBRATION (WBV)?
Whole Body Vibration (WBV) is a relatively new area of interest in medicine with increasing focus on the effects WBV has on various systems. It has demonstrated promise as a new modality in therapy for a number of different disease processes. Utilizing specific frequencies and amplitudes, WBV transmits vibration via vertical (synchronous) or side-alternating (oscillating) platforms to the body while standing on the delivering platform [15, 16]. Frequencies and amplitudes delivered through the vibrating platforms range between 5-90 Hz and up to 10mm respectively [17]. During WBV treatment with low magnitude/high frequency vibration, mechanical stimuli are transmitted throughout the body, loading bone and stimulating sensory receptors and muscle spindles, which in turn causes contractions that lead to tonic vibration reflexes [15-17]. This ultimately elicits a warm-up effect, which can improve muscle power and strength [16].
Many studies utilizing WBV have been performed on patients with neurologic disorders such as Parkinson's, Cerebral palsy, stroke, etc. to evaluate the benefits on spasticity, rigidity, tremor, balance, and muscle weakness [15]. WBV has also been a major area of focus in athletic conditioning and rehabilitation. More recent studies have focused on vibration exercises to prevent osteoporosis and muscular atrophy, to improve muscle strength and balance, to improve skin blood flow, and to improve glycemic control [18-21]. Although not as extensively studied, more recent research is focusing on the application of WBV therapy in T2DM as discussed below. The beauty of utilizing WBV as an exercise modality is the reduced time and effort required of individuals when compared with standard exercise regimens, thus representing a potentially new and novel adjunctive therapy in T2DM.
WHOLE BODY VIBRATION THERAPY AND TYPE 2 DIABETES MELLITUS
Effects of WBV on Glucose Metabolism
Glycemic control is the cornerstone of treatment of diabetes and the degree of glycemic control is directly related to the risk for diabetic complications [2]. Therefore, treatment is aimed at reducing hyperglycemia to minimize these complications. Many studies have demonstrated improved glucose control with the use of WBV therapy. Studies have been performed in murine and human models to evaluate the effects of WBV on glucose control. A clinical report from Germany in 2007 demonstrated superior glycemic control in elderly patients with T2DM treated with WBV when compared to the control [20]. This study utilized a daily horizontal swing administering WBV at 2mm maximum amplitude and a frequency of 30 Hz for three weeks, reporting a decrease in peak fasting glucose concentrations of 6% following oral glucose tolerance testing [20].
Yin et al. studied the effects of WBV therapy on diabetic (db/db) and non-diabetic (db/m) mice. This study demonstrated a reduced HbA1c (~22 %; p <0.05) in the vibrated diabetic mice when compared with nonvibrated diabetic mice; however, WBV did not affect HbA1c levels in the non-diabetic mice (Figure 1) [1]. The authors of this study prompted further speculation that an osteocyte-dependent process may be a likely contributor to the regulation of glucose. The reasoning behind this postulation lies in the bone's role as an endocrine organ secreting osteocalcin which leads to an increase in B-cell mass, insulin secretion, and insulin sensitivity, which ultimately will lower blood glucose [1, 22]. The skeleton undergoes stress secondary to muscle contractions and gravitation during exercise, creating fluid flow within the lacuna-canalicular systems of the bone [1, 23]. This results in osteocyte stimulation to signal for osteoblast synthesis and release of osteocalcin [1, 24]. Therefore, osteocalcin could potentially cause the exercise-induced improvement in insulin sensitivity and glucose control secondary to the exercise stimulated increased release of osteocalcin by bone (Figure 2) [1, 25]. Although the reason for improved glycemic control is unclear, the data from the mouse model strongly suggests that WBV has beneficial effects on glucose metabolism [1].
Figure 1. HbA1c levels of non-vibrated and vibrated db/m and db/db mice; data are mean +/- SD of n=6 animals for each group.
*p<0.05 compared to their respective db/m controls.
**p<0.05 compared to their non-vibrated counterparts [1].
Figure 2. The effect of WBV on glycemic control. Muscle contraction leads to osteocyte stimulation and osteocalcin release, which increases beta cell mass, insulin secretion, and insulin sensitivity, thereby decreasing blood glucose. Energy expenditure with exercise increases the translocation of GLUT-4 receptors, increasing influx of glucose into cells, thereby decreasing blood glucose levels.
Glut-4 is a specific glucose transporter found in adipocytes and skeletal muscle that facilitates movement of glucose into the cell following insulin stimulation which is of particular interest in this topic as resistance training increases energy expenditure as well as insulin-induced membrane translocation of GLUT-4 [1, 10]. If WBV does indeed mimic resistance training and achieves the same physiologic effects, it could stimulate this insulin-induced membrane translocation of GLUT-4, providing an additional logical reason behind the improved glycemic control seen in subjects following WBV therapy (Figure 2).
Pozo-Cruz et al. performed a study on the feasibility and safety of utilizing WBV treatment for 12 weeks to reduce cardiovascular risk factors in T2DM patients with a sedentary lifestyle [11]. They demonstrated a reduction in HbA1c and fasting glucose in patients with T2DM in a primary care setting [11]. Alfonso-Rosa et al. further described the cost-utility of a 12-wk WBV treatment in patients with T2DM, demonstrating that WBV in comparison to standard care is indeed cost-effective [26].
There is great promise with WBV as a treatment modality in patients with T2DM to improve glycemic control. WBV may simulate actual exercise in a manner that stimulates similar pathways thus causing improvement in glucose metabolism. More extensive studies are needed to further evaluate the effects of WBV on glycemic control.
Effects of WBV on Renal Function
Diabetic nephropathy is a major complication affecting approximately 40% of patients worldwide and has been reported as one of the leading causes of renal failure in the United States [2]. The cause of diabetic nephropathy is a result of progressive microvascular disease resulting from a chronic hyperglycemic state. Very few studies have been performed that focus on the effects of WBV on renal function with virtually no discussion of the effect in humans. However, this is a critical system to study secondary to the natural disease process of diabetes largely impacting the renal system. A few select studies exist utilizing murine models that demonstrate promise for improvement in renal function following WBV therapy.
Lin et al. studied WBV benefits on diet-induced obese middle-aged mice to evaluate body composition, exercise performance, and physical fatigue-related and biochemical responses [27]. This study utilized both high frequency WBV (13 Hz, 2mm, 0.68g) and low frequency WBV (5.6 Hz, 2 mm, 0.13 g), reporting a dose-dependent decrease in creatinine that was seen in mice treated with WBV compared to controls (p=0.0020) [27].
In an investigation of diabetic nephropathy performed by Mozaffari et al. there was a reported increase in immunostaining of gamma-H2AX (a marker of cell injury) in renal tissue in diabetic mice when compared with nondiabetic mice [28]. In another study by Baban et al. renal cells prepared from kidneys of diabetic mice demonstrated an increase in IL-17 (pro-inflammatory marker) in diabetic mice when compared to non-diabetic mice [29]. Yin et al. reported a statistically significant decrease in IL- 17 and gamma-H2AX in diabetic mice treated with WBV when compared to unvibrated diabetic mice. This could demonstrate a significant impact on renal function.
Yin et al. further addressed renal function in terms of measuring water intake, urine excretion, and urine osmolality in adolescent diabetic and non-diabetic mice [1]. In this study, WBV did not affect urine osmolality or urine output but did stimulate an increase in fluid intake in the non-diabetic mice [1]. However, the diabetic mice demonstrated reduced fluid intake by 25%, decreased urine excretion, and increased urine osmolality by 28%, consistent with improved urinary concentrating abilities [1].
If whole body vibration can improve creatinine and decrease cellular damage to kidneys, one could postulate that this could have a significant impact on the treatment and prevention of diabetic nephropathy. Additional research is needed in this area to evaluate the effects of WBV on the renal system.
Effects of WBV on Body Mass Composition
If WBV is considered a modification of resistance training exercise then one would expect that it should help decrease body fat, increase lean mass, and improve bone density. In an obese subject, one would expect a decrease in weight following WBV therapy. Unfortunately, current research results that focus on this area are controversial as to the true effect of WBV on body composition.
In a murine model, Yin et al. did not demonstrate a significant difference in weight between vibrated and non-vibrated mice in both the diabetic group and nondiabetic group of mice [1]. However, specific lean mass versus adipose tissue was not evaluated in this model. Lin et al. studied body composition in their research of WBV in diet induced, middle aged mice [27]. This study again demonstrated no difference in body weight; however, they did report a significant decrease in the absolute and relative weight of the liver as well as a frequency dosedependent increase in the absolute and relative weight of brown adipose tissue [27].
With regards to human research, Gonzalez-Aguero et al. studied the effect of WBV on body composition in adolescents with Down syndrome. After measuring upper and lower limb body fat and lean body mass, they reported a reduction in body fat of the upper limbs (p<0.05) and an increase in whole body lean mass following 20 weeks of WBV therapy [30]. Conversely, Pitukcheewanont et al. and Söderpalm et al. reported no difference in femoral fat mass following WBV treatment as measured by Computed Tomography and Dual energy X-ray modalities respectively [31, 32]. Pitukcheewanont et al. did, however, report significant increases of 6.2% in cancellous bone density, 2.1% in cortical bone density, and 6.1% in muscle mass [31]. Pozo-Cruz et al. reported no significant difference in weight in T2DM following a 12-wk WBV regimen, although they did demonstrate a significant reduction in lipidrelated cardiovascular risk factors such as cholesterol, triglycerides, and atherogenic index [11].
Animal models with osteoporosis have been studied and demonstrated improved bone density and bone strength following treatment with short-term lowintensity, high frequency mechanical stimulation [31]. As previously stated, Pitukcheewanont et al. demonstrated an increase in bone density in children, though it was studied in children with pre-existing low bone density [31]. Söderpalm et al. reported no significant change in bone mass, muscle strength, or bone density when studying the effect of WBV therapy in patients with Duchene Muscular Dystrophy but did report an increase in a marker for bone formation: bone-specific alkaline phosphate [32]. Ruck et al. studied WBV therapy in children with cerebral palsy and actually found an increase in areal bone mineral density at the lumbar spine but a decrease in bone density in the diaphysis of the femur in the WBV group [33].
Much controversy exists regarding the effects of WBV on body composition. Although WBV has not been reported to have a significant impact on weight, it may affect individual aspects to overall improve body composition. If WBV can reduce body fat while increasing lean body mass and bone density, it would again demonstrate a possible alternative or adjunctive treatment option for obesity and T2DM. Further research focusing on individual aspects of body composition will be helpful to determine the effects of WBV on fat mass, lean muscle mass, and bone density.
Effects of WBV on Inflammatory Indices
Recent studies have reported that the pathology of diabetes involves chronic inflammatory processes, necessitating treatment of inflammatory events in this patient population [2]. Mozaffari et al. described multiple studies focusing on the interplay of systemic and tissue specific inflammatory events involved in the "diabetesassociated immune response" [2]. Insulin resistance and islet beta-cell dysfunction in T2DM has been reported to be secondary to oxidative stress, endoplasmic reticulum stress, lipid deposition in muscle, liver, and pancreas, amyloid deposition in the pancreas, and more [34]. Donath et al. reported immunological changes altered in obesity and T2DM such as specific cytokines and chemokines, leukocyte populations, tissue fibrosis, and apoptosis, suggesting the relationship between inflammation and the pathogenesis of T2DM [34]. Teixeira-Lemos described the anti-oxidant and anti-inflammatory effects of regular exercise as treatment and prevention of T2DM, recognizing this crucial interplay between inflammation and diabetes [12].
WBV has reportedly exerted beneficial effects on indices of inflammation and cell injury [1]. Yin et al. demonstrated a reduced pro-inflammatory profile and less cytotoxicity in mice treated with WBV by analyzing the whole blood of experimental animals for IL17 (a pro-inflammatory cytokine and marker of T helper cells) and Foxp3 (an antiinflammatory marker of regulatory T cells) expression [1, 35, 36]. IL-17 positive cells and Foxp3 positive cells were significantly reduced and increased respectively in the vibrated diabetic mice when compared to non-vibrated diabetic mice (Figure 3) [1].
Figure 3. FACS analysis of IL-17 (a) and Foxp3 (b) positive cells of peripheral blood obtained from vibrated and non-vibrated db/m and db/db mice; data are mean +/- SD of percent of CD4+ cells of n=6 mice/group.
*p<0.05 compared to their respective controls.
Further evaluation of the expression of gamma-H2AX (a marker of DNA injury) demonstrated a markedly reduced percent of whole blood cells testing positive for gamma- H2AX in the vibrated db/db mice when compared to nonvibrated db/db mice (Figure 4) [1, 28, 37].
Figure 4. FACS analysis of gama-H2AX expression of vibrated vs. nonvibrated db/m and db/db mice; data are expressed as mean +/- SD of percent of total peripheral blood cells (n=6 animals/group).
Overall these studies demonstrated improvement in inflammatory parameters with a decrease in cellular injury following WBV therapy. With inflammation identified as an integral factor in the pathogenesis of T2DM it is necessary to focus on treatments that will affect the inflammatory profile. If these studies can be translated to humans, WBV may indeed improve inflammatory parameter and in turn contribute to the treatment of T2DM.
Effects of WBV on Peripheral Neuropathy in Patients with Type 2 Diabetes
Peripheral neuropathy is commonly found in patients with long-standing diabetes mellitus as a result of progressive microvascular disease causing decreased blood flow to the skin and ultimately peripheral somatosensory deficits. In fact, neuropathies are one of the most common complications of diabetes mellitus, representing roughly 60% of non-traumatic amputations in the United States [19, 38].
Recent research has demonstrated the positive impact WBV has on balance in patients with peripheral neuropathy. Yoosefinejad et al. performed a study evaluating the short-term effects of WBV on the balance and muscle strength of patients with T2DM and pre-existing peripheral neuropathy. They reported significantly increased strength of the tibialis anterior (p=0.004) and quadriceps muscles (p=0.05) after only 6 weeks of WBV therapy [39]. This study also demonstrated a significant decrease in the "Timed Up & Go Test" (p=0.001), a measure of balance, when compared with the control [39]. Johnson et al. reported improved skin blood flow in subjects treated with lowfrequency, low-amplitude WBV [19].
The application for WBV in the treatment of diabetic peripheral neuropathy is multifactorial. Improving distal extremity strength will likely improve balance control, an important consequence of peripheral neuropathy. More importantly, if WBV may be applied in the treatment of T2DM, it could be postulated that if it results in improved skin blood flow then it could potentially prevent, or at least slow the progression, of the microvascular disease effects causing this neurologic sequela.
Effects of WBV on Wound Healing
Yet another significant cause of morbidity and mortality in patients with T2DM are diabetic ulcers and poor wound healing. Approximately 25% of diabetics worldwide develop a foot ulcer, and greater than half of these wounds are unhealed after longterm treatment [40, 41]. Wound healing is intricate and involves multiple cell types and cellular processes such as clot formation, inflammation, epithelialization, angiogenesis, granulation tissue formation, wound contraction, and tissue remodeling [41]. With sustained nutrient and caloric excess there is a dysregulation of energy metabolism, which causes further detrimental effects [2]. Obesity and hyperglycemia cause apoptosis, necrosis, ischemia, hypoxia, cellular swelling, microangiopathy, neuropathy, persistent inflammation, and eventually tissue breakdown and chronic wounds [2]. If WBV can affect the steps of wound healing on a cellular level, one could expect an alteration in wound healing as a result (Figure 5).
Figure 5. WBV effects on factors influencing wound healing.
Weinheimer-Haus et al. described improved angiogenesis and wound healing in diabetic mice. This study evaluated delayed wound healing in diabetic mice receiving excisional cutaneous wounds with the experimental group receiving low-intensity vibration therapy for 30 min/d. At 7 and 15 days wound tissue was collected and evaluated with the vibrated group demonstrating increased angiogenesis and granulation tissue after 7 days of treatment and accelerated wound closure and re-epithelialization at days 7 and 15 of treatment [40].
Yet another important factor impacting wound healing is blood flow to the skin. As discussed earlier, Johnson et al. reported a significant increase in skin blood flow in diabetic patients with peripheral neuropathy receiving WBV when compared to the sham (p=0.115) [19]. Not only would improving skin blood flow likely improve peripheral neuropathy frequently found in diabetes as discussed above, but one would also expect to see an improvement in diabetic foot ulcers and delayed wound healing with improved skin blood flow (Figure 5).
With diabetic complications currently one of the leading healthcare problems in the United States and worldwide, it is necessary to continue the search for treatment modifications. WBV therapy is a potentially new and novel adjunctive therapy that could be beneficial in patients with T2DM. Improvement of weight and glycemic control will have a huge impact clinically for this patient population. Improvement in renal function would highly impact transplant medicine as it stands now with diabetic nephropathy a major factor contributing to the high demand for kidney transplants. Treatment altering the inflammatory pathologic basis of this disease could potentially impact multiple factors and secondary complications seen in this population. Improvement in peripheral neuropathy would not only improve quality of life but could also potentially decrease the incidence of non-healing wounds or injuries as a result of decreased sensation to the lower extremities. Lastly, improvement in wound healing would have a huge impact on the morbidity and mortality of this population.
Subsequent studies are necessary to evaluate the extent of benefits that WBV therapy could provide as an adjunctive treatment modality in T2DM. This subject needs to be further explored with randomized clinical trials of significance focusing on the various pathologic processes behind this multifactorial disease. There have not been any reported negative effects of WBV therapy, and as this could be a potential new and novel therapy, we believe it is not unreasonable to incorporate this treatment modality into the primary care setting.
We would like to acknowledge Michelle Barnes and Edwina Terrell for their administrative help and support, and Jeanene Pihkala at GRU flow cytometry core facility.
None of the authors have potential or existing conflicts of interest.
Yin H, Berdel H, Moore D, Davis F, Liu H, Mozaffari M, Yu JC, et al. Whole Body Vibration Therapy: A Novel Potential Treatment for Type 2 Diabetes Mellitus. Springerplus 2015; 4:578. [PMID: 26543713]
Mahmood S Mozaffari. New Strategies to Advance Pre/Diabetes Care: Integrative Approach by PPPM. New York London: Springer, 2013. Print.
Sabin M, Kiess W. Childhood Obesity: Current and Novel Approaches. Best Pract Res ClinEndocrinolMetab 2015; 29:327-338. [PMID: 26051294]
Onge E, Miller S, Motycka C, DeBerry A. A Review of the Treatment of Type 2 Diabetes in Children. J PediatrPharmacolTher 2015; 20:4-16. [PMID: 25859165]
May AL, Kuklina EV, Yoon PW. Prevalence of cardiovascular disease risk factors among US adolescents, 1999-2008. Pediatrics 2012;6:1035-1041. [PMID: 22614778]
Eaton SB, Konner M, Shostak M. Stone agers in the fast lane: chronic degenerative diseases in evolutionary perspective. Am J Med 1988; 84:739-749. [PMID: 3135745]
Perelis M, Marcheva B, Ramsey KM, Schipma MJ, Hutchison AL, Taguchi A, Peek CB, et al. Pancreatic Beta Cell Enhancers Regulate Rhythmic Transcription of Genes Controlling Insulin Secretion. Science 2015; 350:650. [PMID: 26542580]
Dibner C, Schibler U. A pancreatic clock times insulin release: Circadian oscillators of beta cells control insulin secretion and glucose homeostasis. Science 2015; 350: 628-629.
Neeland IJ, Turer AT, Ayers CR, Powell-Wiley TM, Vega GL, Farzaneh-Far R, Grundy SM, et al. Dysfunctional adiposity and the risk of predia- betes and type 2 diabetes in obese adults. JAMA 2012; 308:1150-1159. [PMID: 22990274]
Hughes VA, Fiatarone MA, Fielding RA, Kahn BB, Ferrara CM, Shepherd P, Fisher EC, et al. Exercise increases muscle GLUT-4 levels and insulin action in subjects with impaired glucose tolerance. Am J Phys 1993; 264:E855-E862. [PMID: 8333511]
Pozo-Cruz BD, Alfonso-Rosa RM, Pozo-Cruz JD, Sanudo B, Rogers ME. Effects of a 12-wk whole body vibration based intervention to improve type 2 diabetes. Maturitas 2014; 77:52-58. [PMID: 24094494]
Teixeira-Lemos E, Nunes S, Teixeira F, Reis F. Regular physical exercise training assists in preventing type 2 diabetes development: focus on its antioxidant and anti-inflammatory properties. CardiovascDiabetol 2011; 28:12. [PMID: 21276212]
de Lemos ET, Reis F, Baptista S, Pinto R, Sepodes B, Vala H, Rocha-Pereira P, et al. Exercise training is associated with improved levels of C-reactive protein and adiponectin in ZDF (type 2) diabetic rats. Med SciMonit 2007; 13(8):BR168-BR174. [PMID: 17660720]
de Lemos ET, Reis F, Baptista S, Pinto R, Sepodes B, Vala H, Rocha-Pereira P,et al. Exercise training decreases proinflammatory profile in Zucker diabetic (type 2) fatty rats. Nutrition 2009; 25:330-339. [PMID: 19062255]
Kantele S, Karinkanta S, Sievanen H. Effects of long-term whole-body vibration training on mobility in patients with multiple sclerosis: A meta-analysis of randomized controlled trials. J NeurolSci2015; 358:31-37. [PMID: 26421830]
Rittweger J. Vibration as an exercise modality: how it may work, and what its potential might be. Eur. J. Appl. Physiol 2010; 108:877-904. [PMID: 20012646]
Matute-Llorente A, Gonzalez-Aguero A, Gomez-Cabello A, Vicente-Rodriguez G, Mallen JAC. Effect of Whole Body Vibration Therapy on Health Related Physical Fitness in Children and Adolescents with Disabilities: A Systematic Review. J Adolesc Health 2014; 54:385-396. [PMID: 24388109]
Tankisheva E, Bogaerts A, Boonen S, Feys H, Verschueren S. Effects of Intensive Whole-Body Vibration Training on Muscle Strength and Balance in Adults with Chronic Stroke: A Randomized Controlled Pilot Study. Arch Phys Med Rehabil2014; 95:439-46. [PMID: 24067865]
Johnson PK, Feland JB, Johnson AW, Mack GW, Mitchell UH. Effect of Whole Body Vibration on Skin Blood Flow and Nitric Oxide Production. J Diabetes SciTechnol2014; 8:889-894. [PMID: 24876449]
Baum K, Votteler T, Schiab J. Efficiency of vibration exercise for glycemic control in type 2 diabetes patients. Int J Med Sci 2007; 4:159-163. [PMID: 17554399]
Rittweger J, Ehrig J, Just K. Mutschelknauss M, Kirsch KA, Felsenberg D. Oxygen Uptake in Whole-Body Vibration Exercise: Influence of Vi bration Frequency, Amplitude, and External Load. Int J Sports Med 2002; 23:428-32. [PMID: 12215962]
Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, Confavreux C, et al. Endocrine regulation of energy metabolism by the skeleton. Cell 2007; 130:456-469. [PMID: 17693256]
Burger EH, Klein-Nulen J. Responses of bone cells to biomechanical forces in vitro. Adv Dent Res 1999; 13:93-98. [PMID: 11276754]
Nomura S, Takano-Yamamoto T. Molecular events caused by mechanical stress in bone. Matrix Biol 2000; 19:91-96. [PMID: 10842092]
Fernandez-Real JM, Izquierdo M, Ortega F, Gorostiaga E, Gomez-Ambrosi J, Moreno-Navarrete JM, Frühbeck G, et al. The relationship of serum osteocalcin concentration to insulin secretion, sensitivity, and disposal with hypocaloric diet and resistance training. J ClinEndocrinolMetab 2009; 94:237-245. [PMID: 18854399]
Alfonso-Rosa RM, del Pozo-Cruz J, del Pozo-Cruz B, Sanudo B, Abellan-Perpinan JM. Cost-utility analysis of a 12-week whole-body vibration based treatment for people with type 2 diabetes: reanalysis of a RCT in a primary care context. Public Health 2015; 129:993-995. [PMID: 25834930]
Lin CI, Huang WC, Chen WC, Kan NW, Wei L, Chiu YS, Huang CC. Effect of whole-body vibration training on body composition, exercise performance, and biochemical responses in middle-aged mice. Metabolism 2015; 64:1146-56. [PMID: 26045298]
Mozaffari MS, Baban B, Abdelsayed R, Liu JY, Wimborne H, Rodriguez N, Abebe W. Renal and glycemic effects of high-dose chromium picolinate in db/db mice: assessment of DNA damage. J NutrBiochem 2012; 23:977-985. [PMID: 21959055]
Baban B, Liu JY, Mozaffari MS. Endoplasmic reticulum stress response and inflammatory cytokines in type 2 diabetic nephropathy: role of indoleamine 2,3-dioxygenase and programmed death-1. ExpMolPathol 2013; 94:343-351. [PMID: 23219834]
González-Agüero A, Matute-Llorente A, Gómez-Cabello A, Casajus JA, Vicente-Rodriquez G. Effects of whole body vibration training on body composition in adolescents with Down syndrome. Res Dev Disabil 2013; 34:1426e33. [PMID: 23474995]
Pitukcheewanont P, Safani D. Extremely low-level, short-term mechanical stimulation increases cancellous and cortical bone density and muscle mass of children with low bone density: A pilot study. Endocrinologist 2006;16:128e32.
Söderpalm AC, Kroksmark AK, Magnusson P, Karlsson J, Tulinius M, Swolin-Eide D. Whole body vibration therapy in patients with Duchenne muscular dystrophy: A prospective observational study. J Musculoskelet Neuronal Interact 2013; 13:13e8. [PMID: 23445910]
Ruck J, Chabot G, Rauch F. Vibration treatment in cerebral palsy: A randomized controlled pilot study. J Musculoskelet Neuronal Interact 2010; 10:77-83. [PMID: 20190383]
Donath MY, Shoelson SE. Type 2 diabetes as an inflammatory disease. Nat Rev Immunol 2011; 11:98-107. [PMID: 21233852]
Aarvak T, Chabaud M, Miossec P, Natvig JB. IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells. J Immunol 1999; 162:1246-1251. [PMID: 21233852]
Zhang L, Zhao Y. The regulation of Foxp3 expression in regulatory CD4(+)CD25(+)T cells: multiple pathways on the road. J Cell Physiol 2007; 211:590-597. [PMID: 17311282]
Kuo LJ, Yang LX. Gamma-H2AX - a novel biomarker for DNA double-strand breaks. In Vivo 2008; 22:305-309. [PMID: 18610740]
Li YF, Burrows N, Gregg E, Geiss L. Declining trends in hospitalizations for non-traumatic lower extremity amputation in the diabetic population: United States, 1988-2006. Diabetes 2010; 59:A50.
Yoosefinejad AK, Shadmehr A, Olyaei G, Talebian S, Bagheri H, Mohajeri-Tehrani MR. Short-term effects of the whole-body vibration on the balance and muscle strength of type 2 diabetic patients with peripheral neuropathy: a quasi-randomized-controlled trial study. J Diabetes MetabDisord 2015;14:45. [PMID: 26052508]
Weinheimer-Haus EM, Judex S, Ennis WJ, Koh TJ. Low-Intensity Vibration Improves Angiogenesis and Wound Healing in Diabetic Mice. PLoS One 2014; 9:1-8. [PMID: 24618702]
Blakytny R, Jude E. The molecular biology of chronic wounds and delayed healing in diabetes. Diabet Med 2006; 23:594–608. [PMID: 16759300]


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Four of America's Historic Hotels in Charleston
Stay with the theme of Charleston carriage tours, cobblestone streets, period homes and old-world charm on your next visit. The city is proud to have four members of Historic Hotels of America, the official program of the National Trust for Historic Preservation that recognizes the finest in America.
Enjoy Charleston's Southern hospitality with touches like free Wi-Fi, wine and cheese or sherry receptions, complimentary afternoon tea, evening turndown service with nightly chocolate and breakfast inclusive.
August 4, 2015 /by Jess
https://mycharlestoncarriage.com/wp-content/uploads/2016/09/Screen-Shot-2015-11-03-at-10.43.18-AM.png 469 472 Jess https://mycharlestoncarriage.com/wp-content/uploads/2016/08/logo-v6.png Jess2015-08-04 14:56:552017-03-23 09:27:02Four of America's Historic Hotels in Charleston
As far as America's top destinations go, you wouldn't associate the mega-attraction of Disneyland with little old Charleston, South Carolina. They're as different as chalk and cheese, in a good way. Interestingly, the visionary and creative genius, Walt Disney, is the one who said it best, "Tomorrow is a heck of a thing to keep up with." So, we don't try.
That's one of the reasons why Charleston Carriage Works appeals to people by embracing the gentle spirit of the past. The clippety-clop of our gorgeous Percheron horse carriage tours brings to mind the days before fast cars, fast food and fast speed broadband.
By taking a tour from Charleston Carriage Works, visitors can embrace the well-preserved beauty and grace of our charming city. It also becomes a learning experience so visitors can re-discover our American roots and explore the history that still exists within our city.
July 24, 2015 /by Jess
https://mycharlestoncarriage.com/wp-content/uploads/2016/09/chas.jpg 325 636 Jess https://mycharlestoncarriage.com/wp-content/uploads/2016/08/logo-v6.png Jess2015-07-24 15:15:152017-03-23 09:27:14Peek Into the Past
Charleston: America's Favorite City
Charlestonians know that it's not polite to brag, but it's acceptable to beam with pride. When Charleston, South Carolina, collected the crown as "America's #1 Favorite City" for the third year straight, we were exceptionally pleased. When we won the title again, we just had to share the news.
https://mycharlestoncarriage.com/wp-content/uploads/2016/09/1400-charleston-sc-sunset.imgcache.rev1409086374211.web_.1400.720-1024x527.jpg 527 1024 Jess https://mycharlestoncarriage.com/wp-content/uploads/2016/08/logo-v6.png Jess2015-07-20 14:50:272017-03-23 09:27:26Charleston: America's Favorite City
History and Horses in Charleston
If our horses could talk, Charleston Carriage Works would be the most remarkable guided tour in the world. Alas, we must settle for our friendly human tour guides who have deep knowledge of history, plus a sense of humor and a vast love of Charleston to share with our guests.
So, we wish you a warm welcome as you climb aboard the carriage for a guided 60 minutes getting to know more about why Charleston, South Carolina is known as "The Cradle of Southern History and Charm."
June 22, 2015 /by Jess
https://mycharlestoncarriage.com/wp-content/uploads/2016/09/Percheron-CCW.jpg 647 800 Jess https://mycharlestoncarriage.com/wp-content/uploads/2016/08/logo-v6.png Jess2015-06-22 13:44:002017-03-23 09:27:36History and Horses in Charleston
A Charleston Carriage Tour For First-Time Visitors
If you're planning a visit to Charleston, South Carolina, for the first time then you are in for a real treat. The only thing that beats getting to the nation's favorite destination for the first time is returning for another visit. You'll want to get a feel for the history without walking your feet off or tiring yourself out from trying to see everything that downtown Charleston has to offer.
June 5, 2015 /by Jess
https://mycharlestoncarriage.com/wp-content/uploads/2016/09/blog-touristsguide.jpg 317 807 Jess https://mycharlestoncarriage.com/wp-content/uploads/2016/08/logo-v6.png Jess2015-06-05 14:47:142017-03-23 09:27:51A Charleston Carriage Tour For First-Time Visitors
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In line with the need to reach out all components of the Syrian political landscape, Special Envoy Staffan de Mistura met in Geneva today with a delegation from the Syrian Opposition Coalition led by Dr. Khaled Khoja.
Mr. de Mistura heard Dr. Khoja's views and perspectives on ways to resolve the ongoing conflict in Syria.
The Special Envoy will continue to meet with various Syrian stakeholders, including the government and other opposition representatives, in order to ensure Syrian participation and ownership in the process leading to a political solution of the conflict.
"The Syrian people must be involved in the settlement of the conflict," Mr. de Mistura said.
"What is currently important is the momentum of what was achieved in Vienna," he said. Everyone agrees that there is an urgency to have a common understanding on how to end this war, this conflict," the Special Envoy said.
Mr. de Mistura will brief the Security Council early next week on the way forward after having held talks in Damascus, Moscow and Washington.
The U.N. Special Envoy for Syria, Mr. Staffan de Mistura, met today in Geneva with His Highness Prince Karim, Aga Khan. Mr. de Mistura and His Highness Prince Aga Khan discussed recent political developments and the humanitarian situation in Syria. They also reviewed ideas for future rehabilitation and recovery.
Mr. de Mistura will brief the Security Council next week on the way forward, following the Vienna recent meeting and after holding talks in Damascus, Moscow and Washington.
Geneva, 06 November 2015
In the framework of the Geneva Consultations, the United Nations Special Envoy for Syria, Mr. Staffan de Mistura, met today with a delegation from the Aga Khan Foundation, composed of Mr. Mohammad Wardeh, Mr. Mohammad Seifo and Mr. Ali Esmaiel. The delegation members discussed with Mr. de Mistura the situation on the ground and shared their perspectives for a political solution.
"Civil society organizations are an important element in conflict resolution, particularly their efforts to ensure that views and concerns of all parts of societies are addressed as they can bring the voice of people and communities on the ground," Mr. de Mistura said at the end of his meeting. "This is why their contribution is critical for a sustainable political solution which would promote human rights, pluralism and democracy," he added.
Geneva consultations are a rolling process to seek views of all Syrian and relevant regional and international parties on the operationalization of the Geneva Communiqué.
In this context, Mr. de Mistura continues to meet separately with Syrian actors from inside and outside Syria, as well as with concerned regional and international players.
Within the framework of the ongoing Geneva Consultations, Deputy Special Envoy Ramzy Ezzeldine Ramzy met today in Geneva with representatives of the Union of Syriac Women and the International Committee of the Red Cross (ICRC), who briefed on the situation in Syria. They discussed ways to support people in Syria in their daily humanitarian needs. Mr. Ramzy also discussed with the representatives of the Union of Syriac Women perspectives on a political solution to the Syrian conflict which could meet the needs of diverse components, which make up integral parts of the Syrian society.
At the end of today's meetings, Mr. Ramzy stressed that, "all should put their differences aside to ensure that aid reaches all those in need, but ultimately only a political solution would allow to address the deepening humanitarian crisis in a sustainable manner." While highlighting the urgent need for a political solution to the Syrian conflict, he added that, "it is critical that women organizations are included in any political process, fully participate in it and contribute to it".
In a press statement issued on 30 May, the United Nations Special Envoy for Syria, Staffan de Mistura, strongly condemned the death of at least 70 civilians in Syria's northern Aleppo province by barrel bombs dropped from government helicopters. "The news of aerial bombing by Syrian helicopters on a civilian market area of the Aleppo neighborhood of Al Shaar deserves the most strong international condemnation," he said. Mr. de Mistura stressed that the protection of civilians during armed conflicts is a cornerstone of international humanitarian law, and applies in all circumstances and without distinction.


Overall dimensions are 18.5" x 1". Mounts with two screws behind dash panel. Some applications will use the same indicator bar even though not all of the symbols may be seen.
From Left to Right; Blank space, Blank space, Blank space, Green Blinker Arrow(L), EXH BRK SW ON, EXH BRK Engaged, Check Trans, Fast Idol, Engine Warning, Check Engine, BRIGHTS headlight(Blue), Brake Warning, ALT Fail, Inlet Air Heater ABS, Park Brake, Low Air, Blank space, Blank space, & Blank space.


This ebook is based out of the Generic 46 Defensive Playbook. Featuring an untouched DT A Gap nano blitz. Most blitzes still come in even with a blocked runningback. New formation featured, Over G. Plays will be continuously added throughout the year like all of our ebooks. Last years average was 50 plays per ebook. Patch Proof.


salted mint & rose watermelon salad with peach vinegar.
I'm in holiday mode. I'm in holiday mood. Tomorrow I'm jumping on a plane, off to spend a few days in Byron Bay, and then a few days in Sydney.
You know what else makes me feel like I'm on vacation? Watermelon on a sunny day. Watermelon in bed. Watermelon with friends. Watermelon anytime, really. It's almost impossible to feel agitated while chomping on a sweet, icy piece of watermelon. It's relaxation therapy via fruity hydration.
Mix all the ingredients together in a bowl. Serve cold.
Note: For strict vegans, make sure the vinegar you use for creating the peach vinegar is of vegan persuasion. Otherwise, go for apple cider vinegar, which as far as I know is invariably vegan.
salted watermelon salad with mint, rose, and peach vinegar.
It sounds wonderful. I had no idea there were non-vegan vinegars!
It's kind of like wine - sometimes the processes involve animal by-products, apparently. Was mulling over whether to leave that note in, actually, as I figured those who were serious about being vegan would know anyway.
This would rock so much right now! THE HEAT!!!
I've only ever made watermelon and feta salad; love this dairy-free take!
oh... very refreshing indeed! and healthy.
It's really satisfying being way over here on the other side of the world and seeing luscious pieces of scented watermelon. My mouth immediately began to water!
You had me at peach vinegar. I swear this would make a perfect summer salad alongside some BBQ ribs and wings.
Watermelon and rose are meant for each other. I'm going to be posting a very similar recipe very soon.
Delicious. Anything with the prefix 'icy' just makes me feel incredibly cold right now, but I know that in time, it will be welcoming.
This looks so yummy! Would have been perfect for me yesterday as it was really sunny here... but today not so much. I'll wait until it's warmer again, then give this a go!
I've never been swayed by watermelon salad - but the addition of peach vinegar and rose water has me sold.
Thanks for sharing. Hope you enjoyed your holiday.
The peach vinegar is completely new to me. Looking forward to checking out your recipe. This sounds so good!
What a great looking salad. I have a recipe for a watermelon salad that is with fetta, olives and mint. But I think your dressing with the peach vinegar is a 'must try'.
Oh Yum. This looks so delicious and fresh. I am up for watermelon at any time, and can eat massive quantities of it. For me, due to where I live, watermelon is purely a summer treat, and so come June, I make up for my sad winter lack of watermelon and eat myself happy. To me it means summer, sun, green grass, and beach towels. This is such a creative way to use it!
Nothing like watermelon on a sunny day and there are so many other gorgeous flavours and textures going on here... I hope you're having a lovely holiday surrounded by brilliant light :).
how interesting! I am curious to try this out!
So fresh and fabulous! love the sound of your peach vinegar too!
Really glad to have some time to catch up on your blog... it's been a crazy month so I have quite a bit of reading to do!
I love the flavor combination here and couldn't agree more on your feelings for watermelon. I'm intrigued by this peach vinegar you speak of!


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Encyclopedia > Mary Martin
Mary Martin
Mary Martin (December 1, 1913 - November 3, 1990) was an American star of (mainly stage) musicals. Amongst the roles originally created by her were those of Nellie Forbush in South Pacific and Maria in The Sound of Music.
1.1 Stage
1.4 Awards
1.5 Autobiography
"Leave It To Me" (1938) Broadway
"One Touch of Venus (1943) Broadway and Tour
"Pacific 1860" (1946), London
"Lute Song" (1946) Broadway
"Annie Get Your Gun" (1947) National Tour
"South Pacific" (1949)
"Kind Sir" (1953) Broadway
"Peter Pan" (1954) Broadway
"The Skin of Our Teeth" (1955) Broadway,Washington DC,Paris
"The Sound of Music" (1959)
"Jennie" (1963) Broadway "Hello Dolly" (1965)Tour, London
"I Do! I Do!" (1966) Broadway, National Tour
"Together On Broadway" with Ethel Merman (1977)
"Do You Turn Summersaults?" (1977) Broadway and Tour
"Legends!" (1986) National Tour
"Over Easy" (1981-1983, PBS, Host)
"America Applauds: an Evening for Richard Rodgers" (1951)
"Ford 50th Anniversary Show" (1953)
"General Foods 25th Anniversary Show" (1954)
"Person to Person" (1954)
"Peter Pan" (1955, 1956, 1960)
"Ford Star Jubilee: Together With Music" (1955)
"The Skin of our Teeth" (1955)
"Hallmark Hall of Fame, Born Yesterday" (1956)
"Annie Get Your Gun" (1957)
"Magic with Mary Martin" (1959)
"Music with Mary Martin" (1959)
"Bing Crosby Christmas Show" (1962)
"Mary Martin, Hello Dolly 'Round the World"(1966)
"Mary Martin at Eastertime" (1966)
"Jack Parr Special" (1972)
"Bing Crosby, His Life and Legend" (1978)
"Standing Room Only: Showstoppers" (1980)
"Beverly Sills Farewell" (1981)
"The Sound of American Music:Rodgers and Hammerstein" (1985)
"Irving Berlin's America" (1986)
"In Performance at the Whitehouse,A Salute to Broadway" (1988)
"Valentine" (1979) (TV)
"Main Street to Broadway" (1953)
"Night and Day" (1946)
"True to Life" (1943)
"Happy Go Lucky" (1943)
"Star Spangled Rhythm" (1942)
"Birth of the Blues" (1941)
"New York Town" (1941)
"Kiss the Boys Goodbye" (1941).
"Love Thy Neighbor" (1940)
"Rhythm on the River" (1940)
"The Great Victor Herbert"(1939)
Donaldson Award, NY Drama Critics Award:"One Touch of Venus"
Special Tony Award: "Annie Get Your Gun"
Tony Award, NY Drama Critics Award: "South Pacific'
Tony Award, Emmy Award : "Peter Pan"
Tony Award: "The Sound of Music"
Peabody Award: "Valentine"
Kennedy Center Honors (1989)
"My Heart Belongs" Morrow (1976)
Personal: Married Ben Hagman 1929- 1936; Richard Halliday 1940 - 1973 (his death)
Son : Larry Hagman[?]
Daughter : Heller Halliday
List of muscles in the human body
... the neck[?] The superficial cervical muscle[?] The lateral cervical muscles[?] The supra- and infrahyoid muscles[?] The anterior vertebral muscles[?] The lateral ...


text:
Skip to content ☰
Publications & conferences
HomePublications & conferences
Recent books about Europe and business-government inter-action are :
Innovation, Governance and Entrepreneurship: How Do They Evolve in Middle Income Countries?
This book analyses the effects of technological development, innovation, entrepreneurship and governance in middle income countries, such as Turkey, in detail. How to best practise innovation and entrepreneurship, which many researchers and policy makers believe to be the main drivers of economic growth and development, has become a fiercely-debated topic. The contributors to this volume consider economic, social and institutional dimensions of innovative thinking, entrepreneurial activity and governance, and investigate both theoretically and empirically how these factors should contribute to the uptake of new technology and the global performance of middle income countries. By offering country specific examples, and by comparing high income and middle income countries, this edited collection presents a comprehensive analysis of innovation, entrepreneurial growth and development outside the vacuum of high income economies, which has traditionally received substantially more scholarly attention.
Revolutionising EU Innovation Policy: Pioneering the Future
The purpose of this ground-breaking book is to inspire the principle of innovation as a permeating program for Europe's societies. After demonstrating early success from the realization of a single market and single currency, the European cooperation process is falling short of delivering much needed results in policy areas which are key for sustainable economic growth and employment, notably innovation policy. Written by authors involved in an independent tripartite High Level Group on EU innovation policy management, Revolutionising EU Innovation Policy analyses the principle causes and offers solutions in order to increase both efficacy and democratic accountability. Presenting the benefits of an overarching innovation policy , the authors draw attention to issues that have been overlooked by research and technology based approaches to innovation, for example culture and education. Importantly, the book examines the interplay between EU innovation policies and the demands of businesses, enterprises, and social and political organizations to fully deploy their innovation potential.
Rethinking the Future of Europe
Rethinking the Future of Europe has brought together three contrasting collections of contributions: the incrementalist perspective concerning the step by step development of Europe, the more radical reform/restructuring approach to the future of Europe, and a view of Europe from the outside. This book features a wide variety of contributions, both in content and focus, with some written as an almost after-dinner discussion while others are deeply academic, supported by an extensive list of references. What holds all together is the deep-seated concern for the citizen, drawing on governance in order to move forward. As Europeans, we are privileged to face such challenge.
A selection of articles and book chapters :
The risk averse society, in Sustainability in a Digital World, Thomas Osburg & Christine Lohmann eds, 2017, p 21-37.
Innovation ecosystem development : a necessary instrument to escape the mid-income trap, in Sefer Sener and Stefan Schepers eds, Innovation, Governance and Entrepreneurship, Palgrave MacMillan 2017, p 11-34.
Revisiting Innovation : revolutionising European innovation policy by means of innovation ecosystem, co-author Klaus Gretschmann, in Klaus Gretschmann & Stefan Schepers eds, Revolutionising EU Innovation Policy, Palgrave-MacMillan 2016, p 1-26
Collaborative Governance : a promising method for innovation, in idem, p 149-192
Beyond the chrystal bal : foresight, in idem, p 309-328.
New governance for new challenges in the EU, in Andrew Kakabadse & Stefan Schepers eds, Rethinking the future of Europe, Palgrave MacMillan 2014, p 77-117
European Innovation Policies and Political processes in the light of Information and Communication Technologies, co-author Claudia Loebbecke, in Festschrift Jörn Kruse, 2013, p 99-113
Governance and innovation policy failures in Europe, Journal of Public Affairs, 2013, Wiley Online Library (www.wileyonlinelibrary.com) DOI: 10.1002/pa.1458
Governance, the new challenge of the African Renaissance, in Journal of Management Development, vol 30, no 9, 2011, p 927-933
The role of Board and CEO in managing political and societal intangibles, in Journal of Corporate Governance, vol 11, no 5, 2011, p 551-559
And a selection of recent speeches :
Open Innovation Strategic Policy Group, EU Commission, key note speech at the annual conference in Dublin, 2014, in Espoo 2015, and in Cluj 2017.
International conference on technology, entrepreneurship and innovation, Istanbul, key note speech in 2015, 2016 and 2017
Comment sauver l'innovation industrielle, key note speech at the Fabrique de l'Industrie, Paris 2016
Annual EUREKA conference, Geneva 2015
The European Round Table of Industrialists, Competitiveness Group, Brussels 2014
Informal Council Competitiveness of EU, Dublin May 2013, on Innovation Ecosystems and the recommendations of the High Level Group on Innovation Policy Management
Open innovation 2.0 conference Stefan Schepers – youtube
Collaboration can take various forms, according to your concerns and short or long term needs.
Sitemap Extra
Stefan Schepers
Place de Luxembourg 2-3
stefan.schepers@eppa.com www.stefanschepers.eu


When looking for an alarm system to help provide security at home, one of the first ones that you find will be the ADT Monitored home alarm system. This alarm system is popular with so many people all over for many different reasons. Knowing what these reasons are can help you decide if this is the right home alarm system for your security needs.
Here are the most important reasons why this alarm system is the first choice for so many people.
1. ADT Monitoring has been around for many years and ADT has a whole team of monitoring professionals working for them. This means that they have a lot of experience in home security. For many people, this is important because they want someone watching their home that knows what to do in case of an emergency and can respond quickly. The ADT team of professionals have been trained so they know exactly what to do for different situations.
2. With an ADT monitored alarm system, you will have 24 hours, 7 days a week security monitoring. This means that no matter what happens, there will always be someone watching to be sure that help is called for right away. This could help to save your family's lives, especially during a burglary or fire.
3. For many people, money is a big issue when it comes to getting a security alarm system. With Protect Your Home, anyone can afford to get good security for an affordable price. No matter how big your home is, Protect Your Home will have security that you can afford.
4. With an ADT monitored home alarm system, you not only get protection from burglary, but you also have security for fires and other emergencies. Protect Your Home, Premier ADT authorized provider knows that more than one danger happens at home, so they make sure they offer alarms with more than one security protection. This s a big plus for any family, especially at night because this is when most fires occur; if your family is sleeping, ADT will call for help and your alarm will sound the danger alert.
These are the most important reasons why the ADT monitored alarm system is the first choice for so many people. You need to decide for yourself if this is the type of home alarm system you need. Just remember that protecting your family is vital these days and knowing you have the best security possible will give you much needed peace of mind and will help to keep your family safe.
Learn how an ADT monitored security system can help protect your home and family.


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Q: How do stars look like from space?
Possible Duplicate:
Optical explanation of images of stars?
What are these rays that appear in photograph of sun?

I thought stars should look round shaped (similar to a sphere, or oblate spheroid) without extra tails nor should they twinkle as they were only caused by atmospheric distortion when seen from Earth. However I searched the web for some justification photos and I didn't find any. I found this photo from NASA which I expect was taken from space, that shows extra tails on the star
http://upload.wikimedia.org/wikipedia/commons/4/4e/Pleiades_large.jpg
Do you have any explanation?


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Home Latest News Ausgrid linesman dies during maintenance work
Ausgrid linesman dies during maintenance work
Image: Jean-Philippe Menard / Shutterstock.com
An Ausgrid linesman has died in hospital on Wednesday, April 3 after being electrocuted while undertaking routine maintenance work in Sydney overnight.
The 39-year-old man, who was a member of the Electrical Trades Union, was part of a crew from Ausgrid's Gore Hill depot who were working on the replacement of a low voltage power pole in Lane Cove when the incident occurred.
ETU Secretary Justin Page said the union was offering its full support to the worker's family and colleagues.
"Our thoughts are with his family, friends, and colleagues at this tragic time," Mr Page said.
"We will be providing whatever practical support we can to assist the family as they deal with the devastating loss of a loved one, along with the emotional and financial hardships that inevitably follow.
"While the union will be working closely with Ausgrid and safety regulators to better understand the cause of this fatality, it is not appropriate to speculate on the cause of the incident today.
"The most important action right now is for this worker's family, friends and colleagues to receive the support they need.
"Once the cause of the accident is known we will strongly advocate for appropriate improvements to safety standards and be vigilant to ensure Ausgrid and other electricity distributors put in place those measures to prevent a repeat of this tragedy."
A spokesperson for Ausgrid said, "We are deeply saddened by the death today of a colleague and line worker who received a serious electric shock whilst carrying out work in the Lane Cove area yesterday.
"Our thoughts and prayers are with his family and we have offered them every assistance.
"We are providing support and counselling to his colleagues who were on site with him on the day.
"The safety of our own people and the public is our number one priority and a SafeWork NSW investigation into the incident is already underway.
"The cause of the incident is not yet known."
AusGrid
ETU
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