text:
Basic Games Code
Code the mood of the whole room! #madewithcode. The player then tries to guess the word, by guessing one letter at a time. Edited by David H. This website is designed to provide you all codes of C and C++ language and also tutorials for learn the concept of these languages. The C# support in Visual Studio Code is optimized for cross-platform. Tutorial 3: Create a matching game. Especially since it is all done in pure Visual Basic with no added game libraries. Guessing Game This script is an interactive guessing game, which will ask the user to guess a number between 1 and 99. For example "FF" in hexadecimal represents number 255 in Decimal. [See games/pc/eamon/ for compiled version 2 games. PlayBasic is a windows based programming language designed for 2D video game creation, and incorporates over 25 years experience in the video game programming field. Dan Crawley June 3, 2014 10:15 AM. For about 7 years, I was writing programs for DOS. I've tried out some of the most entertaining and useful games for learning to code. General Discussion. The Basic Computer Games: Small Basic Edition E-Book is being published with special permission from David H. Some items in C64 Forever, in addition to being published under license or with permission of the respective authors, are or were originally distributed under a license such as the GNU GPL Version 2 or the GNU LGPL Version 2 which, in simple words, require that the source code be included or be made immediately available at no cost and without formalities. TI-89 BASIC GAMES Click a filename to download that file. If you need help with JavaScript. java - The Canvas showing the grid. Play this fun code game for kids and learn about number patterns. I made this game for my computer science summative project. It's one of the millions of unique, user-generated 3D experiences created on Roblox. It is the crudest version with only basic optimization, but has a fully implemented AI. i would like to help you out, first, you should ALWAYS plan your games with pseudocode before writing a single line of code. There is also an executable called M_snake. game_class_example. Code the instruments. Run BASIC Personal Server is an all-in-one system that makes web programming easy and fun. My college had encountered Fortran, several machine languages, Algol, and a couple of special languages. Code you own rules and computer opponents (bots) right in the site embedded editor. Introduction to Game Programming Introductory stuff Look at a game console: PS2 4k code • Can be used in "Micro" or "Macro" mode VU1 – 16k data, 16k code. In this article I'm going to show you how to make a simple game using only the Notepad program and a programming language called "Batch. ♣ Versatile. java - The code for the standalone program, extends GameOfLife. First we will create the AnimatedSprite class since that has the least amount of dependencies. Each day (US Eastern Standard Time) you can solve the same puzzle as everyone else. With a comprehensive curriculum that includes six computer science units and reinforces learning through project-based game development and web development units, kids will progress on a journey from basic. c It is based. In it, they count up through the numbers from 1 to 100. PROGRAM GroceryShopping # Your (pseudo)code here END A Logic Game. This environment is complete enough to run many classic MS-DOS games completely unmodified. Making a game in Flash is easier to understand because you can separate the code of each of these sections in different physical frames. Go beyond an Hour of Code! For teachers For students. You can use code in a number of places within GameMaker: Studio, from objects, to rooms and instances, and there are a number of built in functions that make your life easier when programming, however it is often necessary for you to create your own functions to do a specific task, or to condense. How to code the Leader-board for multi-player games and save player data during the game; Design, Test, and Play your own game from beginning to end; You will be able to use all the concepts and coding you learnt in this course to create your own interactive games on Roblox. deadlines) to get through the first assignments, but by the time be got to Programming Assignment #4 (writing the code for the game called "Breakout") he was completely engaged and extended that basic game in a number of directions without any prompting from us. To get the most out of this series of articles you should already have basic to intermediate JavaScript knowledge. The game and the networking code are abstracted as much as possible for the sake of simplification. There's something very exciting about codes and coded messages that many children love. The following code must be typed into the Code Editor to make this happen: Private Sub Form_Load() tmrTime. It was 101 BASIC Computer Games, I began this article by saying that I admire the modern-day movement to teach more people to code. So create a game in Sinclair BASIC! Use an emulator or real ZX Spectrum 16k, 48k, 128k or ZX Spectrum Next if you have one!. People who knew how to do this stuff are responsible for the "real. J'ai gardé l'esprit du jeu tel qu'il a été créé mais j'ai simplifié certaines parties du code et y ai ajouter des List(of) pour gérer certains objets. Dark Basic Pro is an open source BASIC programming language for creating Windows applications and games. If you don't give them exact instructions, they become confused and make mistakes. Understandably, JavaScript's connection with Java is regularly misunderstood. How to play: Works like any normal snake game, just avoid hitting the walls or yourself, and keep eating the red apple squares. Basic HTML Codes. Some minor differences in the programming syntax, no speedup for the Garbage Collection and the missing machine code entry compatibility prevents the extension to be a perfect BASIC 4. Code the mood of the whole room! #madewithcode. Small Basic is a programming language that is designed to make programming extremely easy, approachable and fun for beginners. Making it while at work so had ~10 minutes of time each day so it took me a few days to complete. In the game of Hangman, the computer chooses a word at random from a given list of words. Feel free to access this source code but always mention the coder or his email [email protected]. This forum is for discussion about any 2D aspect of game creation (sprites, pixelling, platformers, etc) This is the famous Code Snippets board! Post your code. You have a lot of examples such as : New forms elements, GeoLocation, MathML, Drag and Drop, Audio and Video players, 2D Canvas Graphics, 3D Canvas WebGL graphics. BASIC is an interpreted language. Basic Javascript games code Here are games made with javascript. All face down cards are marked by an asterisk. Creative Computing was the original D. CodeMonkey is a fun and educational game-based environment where students learn to code without any prior experience. Free 2D and 3D Game Engines, Game Programming Libraries and Source Code CryEngine. The information and code on this site is provided free of charge by Alyce Watson for Liberty BASIC programmers. Rock Paper Scissors Introduction. Join millions of students and teachers in over 180 countries starting with an Hour of Code. The Basic Computer Games: Small Basic Edition E-Book is being published with special permission from David H. Each day (US Eastern Standard Time) you can solve the same puzzle as everyone else. There's something very exciting about codes and coded messages that many children love. js is a JavaScript library with a very similar syntax to that of the Processing programming language. With just a few commands you can have demos and games up and running on mobile devices. net will teach you the fundamentals of Visual Basic programming. So that other people can look at the source code and distribute their game on more platforms too. Code Examples. Code Orange Games. Step by step lessons with examples. Download a text editor like Notepad++, TextWrangler, or JEdit, and a compiler if necessary. It walks you through the basics of how 2D games work using Visual Basic Andy Dunn - The Z-Man The Z-Buffer Difficulty. At the moment its only a very rudimentary graphics and physics engine based around your code. The color in hex code has a lot more ability and I would recommend that you use it so that you can have a unique website. NET to C#, from C# to VB. You can see AI vs AI go game and get the records as. We'll show a screenshot, and make the programming code available too so you can learn how to make your own!. NET to TypeScript and Java to all others. A simple pinball game in java. FTL-MODULA2-V130. Enjoy! Curated by Sinan Ascioglu Submissions by. After that, I started developing software for Windows, but soon I fell in love with the Unix environment and completely abandoned the world of dos/dos oops dos/win I mean :-) Games. You can browse programs and submit your own under the Submissions tab. HTML Codes format: Each HTML code contains symbol "#" and 6 letters or numbers. Create a Ball Sprite a. Also, please include the name and Profile link of each program's creator. This would be around my 4th month programming, and my second or third in Visual Basic. String Example. Just download Java mini projects and create database according to the information provided. You should always have a VB book in hand for referencing, you can get a copy of Visual Basic 6 Made Easy and VB6 Sample Codes. Visual Basic 2010 Express Tutorials. Use free resources online, like video tutorials and blogs. 0 substitution on the C64. We are the best and most popular cheat codes game site in the world! We add new cheats and codes daily and have millions of cheat codes, FAQs, walkthroughs, unlockables, and much more. Note: For most of these games, you'll need to enable macros. It's interactive, fun, and you can do it with your friends. This code should reverse the ball's direction if it hits the player's paddle. You have a lot of examples such as : New forms elements, GeoLocation, MathML, Drag and Drop, Audio and Video players, 2D Canvas Graphics, 3D Canvas WebGL graphics. Code the instruments. Making it while at work so had ~10 minutes of time each day so it took me a few days to complete. Simple game's source code could always be extended to make it more interesting, but if you end up with a mess of a complicated project – you're in trouble. This program was written by Chris Card for Secret Code Breaker. If you can teach yourself how to write code, you gain a competitive edge over your peers, you can think more algorithmically and thus can tackle. Block Smasher V2. Since at the moment and for quite some time the game development in QBASIC is pretty much dead, the main focus, and not on purpose, will be on FreeBASIC and QB64 game dev output. Visual Basic Tutorials List: Learn Visual Basic 6. Our standard audio library. com Microsoft BASIC Interpreter v5. It was a good experience to learn what it means to finish a game, but in reality, these are just side projects for me to play with some basic game mechanics and learn a little game programming. Add a ||input:on shake|| block to run code when you shake the micro:bit. Liberty BASIC code. They range from introductory lessons on the basic web stuff Coder utilizes (HTML, CSS, Javascript) to more complex projects that show what code can do. Here are links to the Python code discussed in lecture. I know code could be much better with classes or defs but i'm new to programming and I tried to make it short and understandable with very little knowledge of python and pygame. NET, from C# to TypeScript and from VB. Immediately see your game in action, play it with your friends, or let your bots win games for you. These days there's a better way, via the requestAnimationFrame method. Most use VBA and some very basic graphics. This game was coded by Small Basic coder Kenneth Kasajian. zip [15-Aug-1994] GW-BASIC source code of The Wonderful World of Eamon version 1. CodeHS has everything you need to teach computer science at your school, including web-based curriculum, teacher tools, administrator insights, and professional development. In fact, Small Basic is probably the fastest and simplest way I've seen yet to produce and publish Silverlight-based games. Quite BASIC is a web-based classic BASIC interpreter. Its allows development of very complex, windowed based web applications, including mobile app for iOS and Android. This download includes a master set of Visual Basic and Visual C# code samples demonstrating various aspects of the language in the following areas: syntax, data access, Windows Forms, Web development and Web services, XML, security, the. I thought Id post some very simple, short programs that demonstrate how to do some specific things in bB. How to play: Works like any normal snake game, just avoid hitting the walls or yourself, and keep eating the red apple squares. Looking for a quick game to play with two or more players involved? Here's an interesting guessing game that can be played without any accessory. To code, start by choosing a programming language that you want to learn, like HTML5 or C++, which are basic languages for beginners. 00 is the. Online Basic Compiler, Online Basic Editor, Online Basic IDE, Basic Coding Online, Practice Basic Online, Execute Basic Online, Compile Basic Online, Run Basic Online, Online Basic Interpreter, Execute Ya Basic Online (Yabasic v2. *FREE* shipping on qualifying offers. These days there's a better way, via the requestAnimationFrame method. Game programming is one common example of event driven programming. Free Games Available On Origin Thanks To Promo Code The code is said to be limited to one account but others have claimed that they've been able to redeem multiple games with a single code, so. Hangman Script. It is a combination of a game and tutorial where kids experiment with learning to code. tick(60) # Close the window and quit. Feel free to access this source code but always mention the coder or his email [email protected]. 🐱🏍 stuntcat is our open source mini-game we worked on in order to drive pygame 2 development forward. Practice pure code. The Java Connection. Andre Van Wyk: The Game Design Process: How to create any game from start to finish. Tynker offers self-paced online courses for children to learn coding at home, as well as an engaging programming curriculum for schools and camps. Unity Game Source Codes & Templates. So once tired, you are able to save the game and play the rest anytime you wish. NET to TypeScript and Java to all others. For our game, we're going to use a library for writing 2D sprite-based games, using Processing. Did you know that the simple Notepad program on your computer is actually a very powerful programming tool? That's right, and it is also very easy to learn. JavaScript tutorials with example code. We are using the random module with the randint function to get a random number. There are just a few steps to follow in order to write a program onto your TI-83+ or TI-84 calculator using TI-BASIC. Written in 1981 and entirely in BASIC, the game was basically a Pacman clone. Small Basic Pong Game. 2D breakout game using pure JavaScript. Excel Treasure Hunt by Debra Dalgleish - A fun spreadsheet with an explanation of how it was created. The player has 10 turns to guess the word. com/uploads/1/7/7/8/17784759/battleships_v1. Most video games are made using a specialized engine that allows you to "script" events, characters, and so forth without having to code each one from scratch. I know code could be much better with classes or defs but i'm new to programming and I tried to make it short and understandable with very little knowledge of python and pygame. 44 (09-Dec-81). B4X RAD tools include all the features needed to develop great, real-world solutions. " and then "python3 -m freegames. Give or get tips, tricks, and advice. You need to guess what the symbols are and drag the correct letters to replace them so you can reconstruct the secret message. Supports converting code from VB. Creating a Basic MIDP2. This code simply allow you to exit the application when you are finished using it. My college had encountered Fortran, several machine languages, Algol, and a couple of special languages. To get the most out of this series of articles you should already have basic to intermediate JavaScript knowledge. As you saw from the Tetris example, it's never really one mechanic that makes a game. BBC BASIC (Z80) Tatung Einstein version. The game is a deathmatch arena where each player controls a ship able to shoot and drop bombs. You can find him on Google+ and Twitter. Andre Van Wyk: The Game Design Process: How to create any game from start to finish. js is a JavaScript library with a very similar syntax to that of the Processing programming language. It already supports COBOL, which is extremely "vintage", so why not include ASCII BASIC?. written by me. Become the expert. Just click on the blue lettered selection, save and un-zip. You have a lot of examples such as : New forms elements, GeoLocation, MathML, Drag and Drop, Audio and Video players, 2D Canvas Graphics, 3D Canvas WebGL graphics. Dark Basic Pro is an open source BASIC programming language for creating Windows applications and games. Code Orange Games is a new game and miniatures company set in The Netherlands. Processing is a flexible software sketchbook and a language for learning how to code within the context of the visual arts. java - The code for the applet; StandaloneGameOfLife. This Visual Basic Starter Kit is a complete BlackJack card game. A code block consists of a set of instructions, called statements, that are then interpreted by GameMaker Studio 2 and used to make something happen within your game. Computer Programming - Visual Basic Programming Language Examples - Visual Basic Sample Codes - Build a Visual Basic Program with Visual Basic Code Examples - Learn Visual Basic Programming. java - The Canvas showing the grid. List of Free code Game Projects. Also, please include the name and Profile link of each program's creator. 44 (09-Dec-81). String Example. NET, from C# to TypeScript and from VB. All gists Back to GitHub. Learn new concepts by solving fun challenges in 25+ languages addressing all the hot programming topics. I said that I miss BASIC. Game controls: Play Add to your favorites Remove from. Adding an ActiveX Event Callback Function in Visual Basic 6. finally i decided to write a simple game like City Bloxx on mobile phones. Tutorials, Code Samples, References and more!. ♦ Faithful. PureBasic is a native 32-bit and 64-bit programming language based on established BASIC rules. Visual basic projects basically use oracle database for project implementation. vbGORE, Visual Basic Online RPG Engine, is a powerful 2d rpg game engine designed for those who really want to create a commercial game. 23, GW-BASIC Manual, Compiler, tutorials, examples and games, all absolutly free. BBC BASIC is a version of the BASIC programming language. java - Represents a cell. Describe how to make a peanut butter and jelly sandwich. Please add any missing programs below by linking to the program share page. Code Breaking: In this code breaking game there is a phrase written in symbols. Extensive asset library Populate your world by placing down characters, weapons, ammo and other game items. Best of all, many of these tools are free, or almost free, and require no coding background or. The program performs polyalphabetic encryption and decryption using a cipher. Previously we've provided you with some. If you have any questions, ask TheFurryFish. 44 (09-Dec-81). In a previous Appual's tutorial titled "How to Create a Basic Unity Platform Game" (and its part 2), we went over using Unity and the built-in WebGL plug-in to create a simple HTML5-based browser game – in this similar tutorial, we'll be going over how to create a basic Android game using Unity. I learned a lot from this, I have made games before so some of the code is what I reuse/improve from my other games. You can help protect yourself from scammers by verifying that the contact is a Microsoft Agent or Microsoft Employee and that the phone number is an official Microsoft global customer service number. However, there were definitely high level languages out there used. A lot of developers get into software development because they want to build games. There is also an executable called M_snake. zip Several Basic programs from 1000 Magazine (now defunct). I know code could be much better with classes or defs but i'm new to programming and I tried to make it short and understandable with very little knowledge of python and pygame. The player has 10 turns to guess the word. It's one of the millions of unique, user-generated 3D experiences created on Roblox. This program was written by Chris Card for Secret Code Breaker. You can find him on Google+ and Twitter. You need to put links to the data from the files in order for others to be able to use this code. Use free resources online, like video tutorials and blogs. Try a one-hour tutorial designed for all ages in over 45 languages. Supports converting code from VB. You enter the code just as you would expect - function by function. Here are some of the great features of Just BASIC! FREE to use for personal or commercial programming; Great for learning and teaching programming with the included detailed tutorial; Wonderful online community (visit our message forum). Visual Basic Projects with source Code. The following code must be typed into the Code Editor to make this happen: Private Sub Form_Load() tmrTime. Variables and Basic Data Types In our first. Local classes Find a local workshop, school, or summer camp to learn in a. You should always have a VB book in hand for referencing, you can get a copy of Visual Basic 6 Made Easy and VB6 Sample Codes. PC-BASIC aims for bug-for-bug compatibility with Microsoft GW-BASIC. DOSBox is an emulator that recreates a MS-DOS compatible environment (complete with Sound, Input, Graphics and even basic networking). Maybe you can add bonus points for getting to the dot fast for example, changin the color as the time runs out. Minecraft Voyage Aquatic Use your creativity and problem solving skills to explore and build underwater worlds with code. Updated As much as possible! Tons of code examples java visual basic asp and java games and a lot more C\C++,Assembly, html, windows shortcuts, batch programming, Dhtml, PopupMaker. Dan Crawley June 3, 2014 10:15 AM. A pop-up with your Product Code will appear. js is a JavaScript library with a very similar syntax to that of the Processing programming language. Visual Basic Code, Games. You may use it freely for your own programming projects but you may not re-sell or distribute the original files or the source code. It's available in four formats:. Below, we've highlighted six games made entirely in Microsoft Excel. To start, create a new C# Winforms project and call it whatever you want. game_class_example. Code Breaking: In this code breaking game there is a phrase written in symbols. NET Core and VS Code for another relevant article). py; Move a sprite with the keyboard in discrete "jumps. NET, and advanced topics including graphics with GDI+, remoting. CodeMonkey teaches coding using CoffeeScript, a real programming language, to teach you to build your own games in HTML5. Basic HTML Codes. Get the ID of the decal you would like to put on a cape, and subtract 1 from the original ID until the same image appears, except instead of being a decal, it'll be an image. Problem is, when I run this code on the ". For example "FF" in hexadecimal represents number 255 in Decimal. Getting to know GameMaker. 0 for CP/M-86 L80. Name the Sprite "Paddle" 4. So that other people can look at the source code and distribute their game on more platforms too. This is taking longer than usual Try reloading the page. This helps you better understand the logic and the functionality of the code. Large Collection of JavaScript source code. Computer Programming - Visual Basic Programming Language Examples - Visual Basic Sample Codes - Build a Visual Basic Program with Visual Basic Code Examples - Learn Visual Basic Programming. Our standard output library. CodeMonkey. Star Trek is a classic computer game. How to Make a Simple Game in Unity 3D: Unity 3D is a game-making engine that is powerful, simple to use, and most importantly, free to download! (There is a more powerful paid version, but you can do a lot with the free version. com one of our member Chris Iverson (thanks Chris!) has contributed some Liberty BASIC code to solve this problem. sb source code projects in a separate directory so you don't have to re-type any of the Small Basic source code yourself, if you don't want to. Step by step lessons with examples. bas games to download and play. Learn from the best. Read on to see why. Test your child's math accuracy with action-packed game! Fifth graders can join Penelope as she dribbles, shoots, and scores her way across the court by solving basic algebraic equations. The Basic Computer Games: Small Basic Edition E-Book is being published with special permission from David H. Beginning Android Game Programming Basic Game Architecture Code Now we come to the actual coding. I wrote the code myself with Code. Download Visual Basic Projects with source Code, reports and abstracts. The cartridge VicTree Programming for a C64 or a VIC adds 42 commands providing a full BASIC 4. Free Python Games¶ Free Python Games is an Apache2 licensed collection of free Python games intended for education and fun. Dark Basic Professional Edition - It is better to get this professional edition This is a version of basic designed for building games, for example to rotate a cube you might do the following: make object cube 1,100 for x=1 to 360 rotate object 1,x,x,0 next x. Install instructions. page 2 Games 12 games that teach kids to code — and are even fun, too. Yes, please do. NET to C#, from C# to VB. First we will create the AnimatedSprite class since that has the least amount of dependencies. I have made these few games in C ,without any graphics. The code requires Excel 2000 or higher. Regarding Unity, I'm very in doubt that it will occupy web as platform for games nicely, as Unity and any other Emscripten compiled projects, have extremely huge and complex JS files, Unity has tens of megabytes of JS code to be consumed by browser, this is pretty much "not real" for mobile. Practice pure code. End EndIf ' Move piece left If GraphicsWindow. In fact, Small Basic is probably the fastest and simplest way I've seen yet to produce and publish Silverlight-based games. 5 lessons on the basics and extra resources to keep you going. Edited by David H. Code Orange Games. It's very weak and the moves are decided randomly. Perfect source of reference for your VB projects. Input is a fast and easy to use C# Input-Wrapper for use in Games and all other applications. BBC BASIC (86) for MS-DOS full edition. NET to C#, from C# to VB. Supports converting code from VB. NET Core development (see working with. That's good for now! More on Objects and Variables An object is actually more of a definition, rather than a "thing" itself. To get the most out of this series of articles you should already have basic to intermediate JavaScript knowledge. Want to learn how to code but don't know where to start? We've got you covered. Examples might be simplified to improve reading and basic understanding. Use free resources online, like video tutorials and blogs. Welcome to the TI-Basic Developer (TI|BD) Program Archives! We have a large variety of programs available for download, with program filtering and sorting based on genre and metadata, and will accept nearly any programs that you want to add to our archives. Code Orange Games. net: lockr_2 - Advanced Locker in VB. After you buy your game, you might get a confirmation email with your code in it. ' SBace-Invaders-25 (v2) - A space invader game in under 25 lines by Davey~Wavey, Nov. A pop-up with your Product Code will appear. DarkBASIC is a programming language (based on the original BASIC programming language) for creating sophisticated game graphics with very simple commands. Liberty BASIC code. Visual Studio Code is free and available on your favorite platform - Linux, macOS, and Windows. Here are links to the Python code discussed in lecture. Your HTML5 game will undoubtedly need a for loop at some point. If you don't give them exact instructions, they become confused and make mistakes. High School in San Diego, California about 1974 when we had a single teletype terminal connected to an unknown computer. If I recall, Quake3 was converted to run in C# managed code at one point (as a test) and it ran fine. Free Python Games¶ Free Python Games is an Apache2 licensed collection of free Python games intended for education and fun. Describe how to make a peanut butter and jelly sandwich. It runs ASCII, tokenised and protected BASIC programs and supports the Microsoft Binary Format for full interchangeability of data files. You can find him on Google+ and Twitter. Dark-Basic-Pro. The games were written by many people, and compiled by David H. You can use these projects by modifying according to your need of functionality. Free Python Games is an Apache2 licensed collection of free Python games intended for education and fun. It's aimed at coding for kids, but it's definitely fun. Game programming for beginners. Hone your skills as a safe cracker while learning Chinese. 0 ( VB6 Beginners tutorial ) - A comprehensive Visual Basic 6 starter kit for beginners to Visual basic programming. These tutorials contain step by step graphical guides to several visual basic programming concepts and tools. Learn how to use HTML5 with Jscripts. Don't worry, it's not necessary to fully understand this part, but I thought an explanation of the looping code would be beneficial.


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New Star Drive housing development planned
Project near Coppel Soccer Complex would feature one- to four-bedroom units, community building, playground if approved for financing.
New Star Drive housing development planned Project near Coppel Soccer Complex would feature one- to four-bedroom units, community building, playground if approved for financing. Check out this story on chillicothegazette.com: http://ohne.ws/2o4CT9C
Chris Balusik, Reporter Published 10:39 a.m. ET Feb. 14, 2018
This piece of land next to the Donald F. Coppel Athletic Complex off Star Drive is being eyed as the future home of the Paint Creek Station housing complex.(Photo: Chris Balusik/Gazette)Buy Photo
CHILLICOTHE - A new moderate-income housing development is being planned off Star Drive next to the Donald F. Coppel Athletic Complex with start of construction eyed for the spring of 2019.
Paint Street Housing Partners, LLC is in the process of submitting an application to the Ohio Housing Finance Agency for Paint Street Station, a 45-unit development to be situated on more than 11 acres on the Western Avenue side of the access road at the athletic complex that plays host to the Chillicothe Youth Soccer League.
Rod Siddons, chief development officer for Frontier Community Services and Paint Creek Station, LLC, said this project is a bit different than previous ones Frontier has been involved with as it includes units as small as one bedroom and others as large as four bedrooms to accompany the more common two- and three-bedroom units.
The location, which Siddons said has favorable zoning for the type of housing being planned, builds on the company's history of constructing developments on the west end of the city.
"The big things you look for in a site are utilities — sewer, water, electric, gas — and you want great access onto primary roadways," Siddons said. "You want close proximity to jobs and shopping and restaurants and other local businesses — banks, churches, that kind of stuff — and that area gives you all of that. It's been a good area for (housing) development over the last 20 years."
Other developments the company has been involved in the city through the years include Cross Creek Meadows 1 and 2, Bridge Street Landing and Scioto Woods 1 and 2.
The application for the development is being turned into the Housing Finance Agency on Wednesday, with several funding sources in mind including the Housing Tax Credit Program, Housing Development Assistance Program, and Housing Development Loan Program.
The schematic site plan created in conjunction with Lusk Architecture shows the development's entrance coming off the western side of Star Drive just before the cul-de-sac that contains the entrance to the soccer complex. A series of 12 buildings, each containing anywhere from two to four housing units, surround a community building, playground and community garden.
The units, according to information submitted to the city and to the HFA, will consist of open floor plans with an "enhanced lighting package, including various forms of task lighting in the kitchen and bathroom ceilings and lighting under the cabinets." Every unit will include utility rooms with washer/dryer hookups, central air, and new kitchen appliances, and they can be modified to meet the needs of those with physical limitations.
Projected opening collected rents range from around $451 per month for a one-bedroom unit up to around $764 for a four-bedroom unit.
Siddons expects to have the initial feedback to the application from the Housing Finance Agency by mid-June. If selected for funding by the agency, a step two application would be done in September that should position the project for construction to begin in the spring of 2019.
Read or Share this story: http://ohne.ws/2o4CT9C
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redpajama_set_name: RedPajamaCommonCrawl


A former Calhoun man has been arrested in Spencer for selling drugs on a downtown street.
State Police arrested Jerry Scott Wagoner, 37, of Spencer and charged him with possession of a controlled substance with intent to deliver.
A state trooper saw Wagoner on the street corner, and he was questioned. He allegedly told the police he had pills, for which he said he had a prescription.
He reportedly told police he had marijuana he had purchased in Calhoun County for $240 an ounce.
Messages on his cell phone indicated he was using the phone to make drug sales, according to the criminal complaint.
Police found 31 grams of marijuana and hydrocodone tablets.
Wagoner was released on $2,000 bond pending a hearing.
Wagoner had previous drug arrests in Calhoun.


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Ålen kan have flere betydninger:

 Ålen (tidligere kommune), en tidligere selvstændig kommune i Sør-Trøndelag i Norge
 Ålen - The Eel, en japansk prisvindende film
 Et tilnavn/kælenavn for den danske filmmand Peter Aalbæk Jensen
 Aalen - tysk by i delstaten Baden-Württemberg

redpajama_set_name: RedPajamaWikipedia


Among ColourPop's ever-increasing lineup of color cosmetics, their liquid lip colors have arguably become the brands' smash success. That was true of ColourPop's Ultra Matte Lip, and the arrival of their Ultra Satin Lip was heralded with a lot of social media fanfare. The good news is that we found it to be worth the hype, with one caveat (we'll get to that in just a moment).
Like its sister product Ultra Matte Lip, Ultra Satin Lip comes in a clear plastic tube with a reflective silver cap that holds a sponge-tipped wand applicator. It's standard packaging for such products, but where this product starts to distinguish itself is in how it feels on lips.
Ultra Satin Lip has a whipped mousse-like texture. It's remarkably lightweight and applies smoothly, without pulling or dragging. That lightweight feel holds true during the entire wear time, which, if you don't eat a meal, is around six hours.
The fragrance-free formula also gets high marks when it comes to pigment quality; you don't need much at all to get full, opaque color. Speaking of colors, there's something for just about everyone, with a range of shades that includes true neutrals to bold reds and even a couple of shades of purple (including an everyday wearable shade and a bolder option).
The finish of Ultra Satin Lip is, true to its name, satin. It starts out with a slight sheen after you apply it, but quickly dries to a low-glow finish and remains that way through its wear time (and unlike Ultra Matte Lip, this does not feel drying). ColourPop makes a note that this not transfer-proof (it will show up on glasses or cups), but it does hold up very well before fading to an attractive stain.
The only drawback is that for some of the darker shades, some feathering and bleeding does occur after a couple of hours into their wear time. We did not find this to be as much of an issue with the lighter shades, but if you choose a bolder option know that wearing a liner under it is recommended.
Other than that quibble, ColourPop's Ultra Satin Lip gets high marks from us, and for the price, you can afford to try out a few shades to find what might be your new favorite lip color!
Lightweight, whipped mousse texture is easy to apply.
The darker shades tend to feather after a couple of hours.
Our Ultra Satin Lip is a lightweight, bold lipstick with a Satin finish. A super comfortable feel and healthy satin look for you lips. Ultra Satin Lip has a crazy high percentage of pigments for extra intense colour saturation. This lipstick is extremely long wearing, although not completely kiss proof you may leave some marks on your coffee cup!
Dimethicone Crosspolymer, Isododecane, Diisostearyl Malate, Disteardimonium Hectorite, Propylene, Carbonate, Hydrogenated Polyisobutene, C10-18 Triglycerides, Oryza Sativa (Rice) Bran Wax, Pentylene Glycol , Silica Silylate, Silica, Polyethylene [+/- Blue 1 Lake (Ci 42090), Iron Oxides (Ci 77491), Iron Oxides (Ci 77492), Iron Oxides (Ci 77499), Mica (Ci 77019), Red 27 Lake (Ci 45410), Red 28 Lake (Ci 45410), Red 6 (Ci 15850), Red 7 Lake (Ci 15850), Titanium Dioxide (Ci 77891), Yellow 5 Lake (Ci 19140), Yellow 5 Lake (Ci 19140:1), Yellow 6 Lake (Ci 15985)]. *Note: Ingredients may vary based on individual shade/finish.


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text:
Tom Osborne, Dick Fosbury Headline 2018 Hall of Fame Class
By NFHS on April 24, 2018 awards
From left: Tom Osborne, Carrie Tollefson, Dick Fosbury
Tom Osborne, the 1955 Nebraska High School Athlete of the Year who later led the University of Nebraska to three national football championships in 25 years as the school's coach, and Dick Fosbury, who revolutionized the high jump as a high school athlete in Oregon when he developed a technique that became known as the "Fosbury Flop," are among 12 individuals selected for the 2018 class of the National High School Hall of Fame administered by the National Federation of State High School Associations (NFHS).
Osborne was a three-sport standout (football, basketball, track and field) at Hastings (Nebraska) High School in the early 1950s before becoming one of the most successful coaches in college football history. Fosbury developed the upside-down, back-layout leap known as the Fosbury Flop at Medford (Oregon) High School and later perfected it by winning the gold medal at the 1968 Olympics in Mexico City.
Other former high school athletes chosen for the 2018 class are Nicole Powell, one of Arizona's top all-time girls basketball players during her days at Mountain Pointe High School in Phoenix who later excelled at Stanford University and in the WNBA, and Carrie Tollefson, who won five state cross country championships and eight individual track titles at Dawson-Boyd High School in Dawson, Minnesota, before winning individual and team NCAA titles while competing at Villanova University and qualifying for the 2004 U.S. Olympic team.
Five outstanding coaches were selected for the 2018 class, including Miller Bugliari, the all-time leader nationally in boys soccer coaching victories with a 850-116-75 record in 58 years at The Pingry School in Basking Ridge, New Jersey, and Dorothy Gaters, the Illinois state leader with 1,106 career victories in 42 years as girls basketball coach at John Marshall High School in Chicago who won her ninth Illinois High School Association state title last weekend.
Other coaches who will be honored this year are Buddy Anderson, the winningest football coach in Alabama history with 329 victories the past 40 years at Vestavia Hills High School; Jeff Meister, girls and boys swimming coach at Punahou School in Honolulu, Hawaii, who has led his teams to a combined 34 Hawaii High School Athletic Association state championships; and Bill O'Neil, who retired last year after winning almost 1,300 games as the boys ice hockey, girls soccer and girls softball coach at Essex High School in Essex Junction, Vermont.
The other three members of the 2018 class are Roger Barr, who retired in 2015 after a 43-year career in high school officiating in Iowa, including the final 13 years as director of officials for the Iowa High School Athletic Association; Dick Neal, who retired in 2013 after a 34-year career as executive director of the Massachusetts Interscholastic Athletic Association; and Bill Zurkey, who retired in 2012 after an outstanding 35-year career as a choral director in three Ohio schools, including the final 25 years at Avon Lake High School.
These four athletes, five coaches, one contest official, one administrator and one performing arts director will be inducted into the National Federation of State High School Associations (NFHS) National High School Hall of Fame July 2 at the Chicago Marriott Downtown Magnificent Mile in Chicago, Illinois. The 36th Hall of Fame Induction Ceremony will be the closing event of the 99th annual NFHS Summer Meeting.
The National High School Hall of Fame was started in 1982 by the NFHS to honor high school athletes, coaches, contest officials, administrators, performing arts coaches/directors and others for their extraordinary achievements and accomplishments in high school sports and performing arts programs. This year's class increases the number of individuals in the Hall of Fame to 470.
The 12 individuals were chosen after a two-level selection process involving a screening committee composed of active high school state association administrators, coaches and officials, and a final selection committee composed of coaches, former athletes, state association officials, media representatives and educational leaders. Nominations were made through NFHS member associations.
Following is biographical information on the 12 individuals in the 2018 class of the National High School Hall of Fame.
Dick Fosbury revolutionized the high jump when, as a sophomore at Medford (Oregon) High School in 1963, he used his new technique which became known as the Fosbury Flop. The upside-down, back-layout style became the standard as all records around the world have been established by athletes using the Fosbury Flop. Using his new method, Fosbury improved his jumps from 5-4 as a sophomore to 6-5½ as a senior and placed second in the state meet. He continued to perfect the "Flop" at Oregon State University, where he claimed the NCAA high jump title in 1968 with a 7-2¼ effort. That same year, Fosbury won the gold medal at the 1968 Olympics in Mexico City with a 7-4¼ jump, which broke both the Olympic and American records. Fosbury was named to the USA Track and Field Hall of Fame, the U.S. Olympic Hall of Fame and the Oregon Sports Hall of Fame. He retired in 2011 after 30 years as a civil engineer in Idaho, but he continues to coach athletes at Dick Fosbury Track Camps in Maine and Idaho.
Tom Osborne was one of Nebraska's top high school athletes during his days at Hastings High School from 1951 to 1955. He was the starting quarterback on the football team and helped the basketball team to the Class A state championship in 1954. In track and field, Osborne was state champion in the discus and runner-up in the 440-yard dash. In addition, he played American Legion baseball and helped his 1954 team to a second-place finish in the state tournament as a third baseman and pitcher. Osborne earned all-state honors in basketball and football and was named Nebraska High School Athlete of the Year in 1955. After an outstanding career at Hastings College and a few years in the National Football League, Osborne began his college coaching career. In 25 years as football coach at the University of Nebraska, Osborne compiled a 255-49-3 record, with 25 consecutive bowl appearances, 13 conference titles and three national championships. Following his coaching career, Osborne was elected to the U.S. Congress, and then returned to Lincoln in 2007 to serve as the Nebraska athletic director for five years.
Nicole Powell was one of the top basketball players in Arizona history during her four years (1996-2000) at Mountain Pointe High School in Phoenix. She collected 1,820 rebounds (eighth all-time nationally) and scored 2,486 points – second highest in state history. She helped her teams to three second-place finishes in the Arizona Interscholastic Association state tournament. As a senior, Powell also won the state discus event in track and field and the singles state title in badminton, and she also participated in tennis and cross country. Powell continued to excel at the next level, leading Stanford University to four Pacific-10 Conference basketball titles. She averaged more than 17 points and almost 10 rebounds per game and was named Pac-10 Player of the Year two times. Powell was the No. 3 overall selection in the 2004 WNBA draft and played 11 seasons with five teams. After her playing career ended, Powell became assistant women's basketball coach at the University of Oregon before being named head women's basketball coach at Grand Canyon University in Phoenix in April 2017.
Carrie Tollefson won five Minnesota State High School League state cross country championships at Dawson-Boyd High School from 1990 to 1994, including the first as an eighth-grader. She also won eight individual track and field titles in the 1600 and 3200 meters, and she set a state record in the 3200 meters in 1994 with a time of 10:30.28. Tollefson's 13 individual titles in cross country and track are the most ever in the state. Tollefson's dominance continued at Villanova University, where she won five individual NCAA titles – the indoor and outdoor 3K, the outdoor 5K and two cross country titles – and helped her team to the 1999 NCAA team championship. She was a 10-time All-American and the 1998 NCAA Indoor Track Athlete of the Year. Tollefson made the 2004 U.S. Olympic team and participated in the 1500 meters in Athens, Greece. Since her competitive days concluded, Tollefson has conducted distance running camps and served as a motivational speaker and clinic presenter, and she hosts a weekly online show on running and fitness entitled "C Tolle Run."
Buddy Anderson is Alabama's all-time winningest football coach – at any level. Not only is he the top high school football coach with 329 victories in 40 years at Vestavia Hills High School, he has more wins than college coaches Paul "Bear" Bryant (323), Nick Saban (216), Ralph "Shug" Jordan (176) and Pat Dye (153). Anderson's teams have won 16 area and region championships and made 30 state playoff appearances, including state championships in 1980 and 1998, when his team finished 15-0 and was ranked nationally. Despite the demands of being a head football coach, Anderson has also served as the school's athletic director for 40 years, and the school's teams have won 65 state championships during his tenure, including 13 state wrestling titles and nine state baseball championships. Anderson was selected Alabama Coach of the Year three times, and he was inducted into the Alabama High School Sports Hall of Fame in 2003.
Miller Bugliari is an icon at The Pingry School in Basking Ridge, New Jersey, where he has been the school's boys soccer coach since 1960. The 82-year-old Bugliari has amassed a national record 850 victories and led his teams to 26 Prep A and New Jersey State Interscholastic Athletic Association state championships. His teams have registered 20 undefeated seasons and won 27 county championships. Bugliari has been named New Jersey State Coach of the Year seven times, and he has earned four National Coach of the Year awards. He is a former president of the National Soccer Coaches Association of America and was inducted into the NSCAA Hall of Fame and the National Soccer Hall of Fame in 2006. Bugliari was a teacher in the Science Department at Pingry for many years and now is Special Assistant to the Headmaster.
Dorothy Gaters is the Illinois High School Association's (IHSA) career leader in basketball coaching victories – for both boys and girls. After completing a 22-7 season at John Marshall High School in Chicago last weekend and winning her ninth IHSA state girls basketball championship, Gaters' record stands at 1,106-198. Her teams won the Class AA title in 1982, 1985, 1989, 1990, 1992, 1993 and 1999, and the Class 3A title in 2008. Gaters' teams at John Marshall have finished second three other times and third on six other occasions. During her 42-year career at John Marshall, her teams have won 24 Chicago Public Schools championships and qualified for the IHSA state finals 26 times. Gaters was inducted into the Illinois Basketball Coaches Association Hall of Fame in 1996 and the prestigious Women's Basketball Hall of Fame in 2000. She was selected as a coach for the Junior Olympic team in 2000 and the McDonald's All-American Game in 2011.
Jeff Meister has become one of the top swimming coaches in the nation during the past 30 years at Punahou School in Honolulu, Hawaii. Taking over the Punahou swimming program in 1988, Meister has led the boys and girls teams to 34 Hawaii High School Athletic Association (HHSAA) state championships – 16 boys and 18 girls – including 2018 titles for both squads last month. Although the Punahou program had enjoyed success in swimming prior to Meister's arrival (47 all-time boys state titles, 51 all-time girls state titles), he has taken the program to another level and is the winningest high school swimming coach in state history. Meister's teams have won 34 Interscholastic League of Honolulu (ILH) championships, and he has been named ILH Coach of the Year 24 times. Meister has also served as the school's athletic director for nine years after 11 years as associate athletic director. In addition, he has served as HHSAA State Track and Field Coordinator for 14 years and State Swimming Coordinator for eight years. Meister is currently serving a term on the NFHS Swimming and Diving Rules Committee.
Bill O'Neil was one of the top multi-sport coaches in Vermont history – and perhaps nationally – during his 45-year coaching career at Essex High School. O'Neil compiled a 396-176-52 record in 37 years (1979-2015) as girls soccer coach, a 636-292-33 record in 44 years (1973-2017) as the boys ice hockey coach and a 261-124 record in 22 years (1979, 1992-2012) as the girls softball coach. This rather unique girls-and-boys sport combination yielded an overall record of 1,293-592-32, which is almost 2,000 varsity games coached at Essex. O'Neil led his various teams to 24 Vermont Principals' Association state championships – 14 in hockey, six in girls soccer and four in girls softball. He has received numerous coach-of-the-year awards in all three sports. Though he has retired from his coaching duties, O'Neil continues to serve as an English teacher at Essex High School, which he has done since joining the faculty in 1965.
Roger Barr devoted 43 years of his life to the avocation of officiating – first as a high school football, basketball and baseball official in Iowa for 30 years, followed by 13 years as director of officials for the Iowa High School Athletic Association (IHSAA). Barr was one of the top-rated officials in all three sports throughout his career, which earned him numerous playoff assignments. In football, Barr officiated 30 state tournaments, including 10 championship games. In baseball, he worked 26 state tournaments, including 24 championship contests. And in basketball, he officiated 26 state boys tournaments and 27 state girls tournaments, which included a total of 22 championship games. Barr conducted rules interpretation meetings in all three sports throughout the state during his officiating days, and in 2003, he joined the IHSAA staff as director of officials. He conducted rules meetings and clinics for the IHSAA for 13 years before retiring in December 2015.
Dick Neal retired in 2013 after 34 years as executive director of the Massachusetts Interscholastic Athletic Association (MIAA). At the time of his retirement, Neal was the longest-tenured active director of a state high school association. He also served as chief executive officer of the Massachusetts Secondary School Administrators Association (MSSAA) for 34 years. During his tenure as MIAA executive director, Neal was responsible for initiating the effort to increase leadership of both women and minorities in high school sports in Massachusetts, and he wrote and recommended the amendment that created the MIAA Standing Committee on Sportsmanship, Integrity and Ethics. Neal served a term on the NFHS Executive Committee from 1989 to 1992 and was vice president during his final year. He also served as a member of the NFHS Strategic Planning Committee and director of the NFHS Fund Administrators Association. Neal previously received the NFHS Citation and the National Interscholastic Athletic Administrators Association (NIAAA) Distinguished Service Award.
Bill Zurkey had a profound impact on thousands of young people during his career as a choral music director at three Ohio high schools. After 10 years at Toledo DeVilbiss High School and Vermillion High School, Zurkey moved to Avon Lake High School in 1987 to rejuvenate a music program that was spiraling downward. In a short time, Zurkey expanded the choral program from less than 100 singers to more than 400. His squads won Ohio Music Education Association superior ratings for 20 years. Despite his full load of music classes, including teaching AP Music Theory and serving as chair of the Fine Arts Department, Zurkey was the eighth-grade football coach for 24 years, as he helped build a program which led to Avon Lake High School winning the Ohio High School Athletic Association state football title in 2003. Since his retirement in 2012, Zurkey has been a teacher at Cleveland State University and is in his sixth year as director of the Cleveland Pops Chorus. Zurkey is the 13th individual to be inducted in the Performing Arts category in the National High School Hall of Fame.
NFHS Adopts New Logo as it Leads into Next 100 Years
NFHS to Host Annual Student Leadership Summit in Indianapolis
New Course Available in NFHS Learning Center for Adapted Sports Coach.
"From Chicago to Indy – The First 100 Years" Commemorative Book Now A.


Amit Kanda, VP of Oracle (Global Strategy & Product Cloud Services) at the Fujitsu and Oracle launch of Oracle Cloud at Customer. The companies have formed a partnership to provide Cloud service to local business, Sangre Grande Room, Hyatt Regency, POS. Thursday, July 19, 2018. PHOTO BY ROGER JACOB.
Cloud computing is transforming the way companies work, allowing them to efficiently and cost-effectively scale up or scale down services as needed.
Cloud computing is defined as the practice of using a network of remote servers hosted on the internet to store, manage, and process data, rather than a local server or a personal computer.
Describing this as a "transformational technology", president and CEO of Fujitsu Caribbean, Mervyn Eyre believes Caribbean businesses cannot afford to get left behind when the global trend is towards cloud storage.
"As a Caribbean citizen, I have deep concerns about where we are in cloud adoption. I think we're far behind and a lot of it has to do with a number of things. I think one is governance issues, at the level of IT (information technology) maturity – concerns about not wanting to let go of our own environment – but that time has passed.
"There's no question that this (cloud adoption) has to happen if we're going to be able to get the benefits of surviving in a digital society. That's one of the reasons why Oracle and Fujitsu are here, because we want to make that journey safer. We feel there's a responsibility we have to bring this technology to the table, to be able to build trust and confidence in public cloud technology," he said.
"I think we need to get these barriers broken," Eyre added, "so that we can get the benefit of economies of scale and get the benefit of scale generally, to be able to get our businesses moving into this space to become digitally relevant."
Eyre was speaking with reporters on July 19 at Hyatt Regency where Fujitsu and Oracle held a presentation about Oracle Cloud at Customer, for which Fujitsu is the sole provider in the Caribbean.
This new agreement allows Fujitsu to directly provide Oracle Cloud Services to customers as part of any hybrid IT or modernisation project.
Fujitsu said under the agreement, it will deliver Oracle Cloud at Customer to public and private sector companies in TT and the wider Caribbean from its Trinidad Data Centre, with local companies having the option to install the services at their premises.
This, it added, will enable "the rapid build out of multiple cloud environments and high quality multi-cloud operations" while its strategic alliance with Oracle "provides robust cloud offering to customers in the Caribbean to support digital transformation."
Fujitsu and Oracle form a partnership to provide Cloud service to local business, Sangre Grande Room, Hyatt Regency, POS. Thursday, July 19, 2018. PHOTO BY ROGER JACOB.
On its website, Oracle explained the benefits of this particular service.
"Rather than procuring hardware, installing software and managing the system, you easily consume the same cloud services on your premises, just like you do in Oracle Cloud. Oracle Cloud Machine includes a wide range of Oracle Cloud services - Oracle Platform as a Service (PaaS), Oracle Compute Infrastructure as a service (IaaS), and Oracle Software as a Service (SaaS). You can use these cloud services as building blocks to accelerate the development of your innovative applications while maintaining complete control of your data and systems.
"Operated by Oracle in your data centre for your convenience and available as a subscription, Oracle Cloud at Customer delivers the benefit of aligning spending with the revenue realised from applications. Oracle supplies the hardware, installs the software, and handles the day-to-day operations," Oracle stated.
Another aspect of Cloud at Customer, highlighted during the recent presentation, is its flexible subscription pricing, also known as pay as you go.
VP of Product Management at Oracle, Amit Kanda, told reporters, "When the customer builds their own environment, they have to buy the memory and the processors and the storage for their peak load, which may only happen one day of the year...When we offer it as a service, there is an initial cost the customer has to pay but beyond that, it's all pay as you go."
Pointing out that pay as you go is an integral part of the cloud offering, Kanda said, "It's available both in our public cloud and Cloud at Customer. We are bringing cloud behind a customer's firewall. We are giving them the same flexibility of payments as we offer them in the public cloud."
Asked by Business Day if Oracle added flexible subscription pricing because of customer demand, Kanda said yes, explaining there were two reasons for doing so.
"One is that the cloud offers the capability to the customer to pay for the service on an (as-needed) basis – they don't have to spend all the money up front. The second part, which customers expect with cloud, is flexibility of payment. Just like electricity at home, you pay as you use. Customers expect to pay only for their actual usage of cloud services."
Cloud at Customer may be fairly new to the Caribbean, but since its introduction in 2016 it has experienced what Oracle described as "unprecedented growth, with leading global organisations across six continents and more than 30 countries adopting the solution, including AT&T and Bank of America."
Kanda said public sector bodies are among the leaders in adoption of Cloud at Customer, including in Colombia and Brazil.
"The Colombian Federation of Municipalities is adopting Cloud at Customer to modernise their municipalities. Similarly, we have customers in Brazil who are in the public sector. So we do see a good adoption of Cloud at Customer with the public sector (because of) security. They are carrying lots of citizen data and they want to ensure that, that data is maintained within the constraints of public sector data centres."
Adding to Kanda's point about security, Eyre said Fujitsu has heard a lot about cloud security concerns, which is one reason why the company decided to bring Oracle Cloud at Customer into the regional market.
"You can actually put your cloud platforms now behind your own firewall. This is one of the reasons why this technology is very important. You can have it on your premises or in Fujitsu's data centre, closer to you, with your own security policies, your own security, along with some of the Oracle security technology to be able to support it. That's one of the reasons we're actually doing this, to actually be able to give our customers a feeling of a safer route towards the public cloud," Eyre said.


text:
A next-gen network with last-gen phone policies. —
Update: Verizon says its Pixels will get updates at the same time as Google's
Verizon apparently has turned over a new leaf and "won't stand in the way of updates."
Ron Amadeo - Oct 12, 2016 4:07 pm UTC
Update 2: Google agrees! The company told Ars "OS updates and monthly security patches will be updated on all Pixel devices (Verizon and non-Verizon versions) simultaneously."
Update: A Verizon spokesperson has reached out to Ars with the following corrections about its version of the Pixel:
"First and foremost, all operating system and security updates to the Pixel devices will happen in partnership with Google. In other words, when Google releases an update, Verizon phones will receive the same update at the same time (much like iOS updates). Verizon will not stand in the way of any major updates and users will get all updates at the same time as Google.
Also, the Verizon version of the Google Pixel is carrier unlocked, so you can use it where ever you like. Finally, we have three apps pre-installed on the phone Go90, My Verizon (which is your account management tool) and Verizon Messages (your messaging app). As you noted, all three can easily be uninstalled by the user."
Google told 9to5Google that "system updates will be managed by Verizon for Verizon models," which in the past this has meant slower, delayed updates. Verizon seems to be changing its update strategy for the Pixels, and now promises to "not stand in the way of any major updates." We've reached out to Google for comment and clarification.
The Google Pixel phones are coming, and they're even being sold through a carrier: Verizon. I've speculated a few times now that it would be a terrible idea to purchase the Pixel through Verizon, however, and now Google has offered official confirmation that it is indeed a terrible idea to purchase the Pixel through Verizon.
Google gave the following statement to 9to5Google: "Monthly security updates will come from Google (for all models), and system updates will be managed by Verizon for Verizon models, and Google for unlocked models bought from Google Store."
This is better than I expected. Security updates will come from Google, so they will actually arrive on time. Verizon, however, is still free to stand in the way of your major updates, so don't expect to get them in a timely manner.
Hands-on with the Pixel and Pixel XL: Google's iPhones seem fine
The Pixel phone has a very odd relationship with Verizon. In the US, Google and Verizon are advertising the device as a "Verizon Exclusive," but the Pixel phones are also available unlocked from the Google Store, Best Buy, Verizon, Target, and Walmart. Verizon isn't even the only cell carrier with the Pixel—you can also buy it from Google's "Project Fi" MVNO. The "Verizon Exclusive" marketing is doubly confusing when you consider the phone will work on any US carrier.
Some people buy devices from a carrier because they don't want to pay the full unlocked price up front, but this year Google is also offering financing plans that are identical to what a carrier would offer. The company also has a two-year "device protection" plan for $100 that is similar to the insurance carriers offer.
If you want to buy a Pixel phone, please don't buy the inferior Verizon version. You'll get a locked bootloader, delayed major updates, and there will even be (uninstallable, but still) Verizon crapware. If you really want to use the Pixel on Verizon, we recommend buying it unlocked and slapping in a Verizon SIM.
Ron Amadeo Ron is the Reviews Editor at Ars Technica, where he specializes in Android OS and Google products. He is always on the hunt for a new gadget and loves to rip things apart to see how they work.
Email ron@arstechnica.com // Twitter @RonAmadeo


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text:
Solid-Phase Synthesis of Biomolecules
Rolf Breinbauer, University of Leipzig, Germany
doi: 10.1002/9780470048672.wecb552
The synthesis of biopolymers, tool compounds, and molecular probes lies at the heart of any effort in chemical biology. Solution-phase strategies are well established but usually require considerable efforts in time and labor during workup and purification steps. In contrast, solid-phase synthesis, in which the substrate is covalently bound to an insoluble support, allows the simple removal of excess or consumed reagents by simple filtration. In the cases of oligonucleotides and peptides, the synthetic operations can be performed by robotic systems allowing the high-throughput synthesis of these biopolymers at low cost within a short time. The solid-phase synthesis of oligosaccharides and small-molecule probes has made significant progress during the last several years.
This article gives an overview of the main technical aspects of solid-phase synthesis and reviews the application of this technique for the synthesis of oligopeptides and proteins, oligonucleotides, oligosaccharides, and small molecules.
Biologic Background
From the mid-nineteenth century onward, researchers have made tremendous strides in understanding the molecular nature of living organisms. The discovery that cellular catalysts ("enzymes") are composed of oligomers of amino acids; that genetic information is encoded in oligonucleotides; the solving of the puzzle of metabolic pathways; and the investigation of hormonal and cellular signaling have shaped the modern view of what has become molecular and cellular biology. These discoveries have been accompanied by progress in both analytical techniques as well as in the synthesis of these molecules. Even today, the investigation of cellular organisms offers new surprises, such as the catalytic nature of RNA ("ribozymes"), the pathogenic nature of proteins ("prions"), or the silencing of genes via RNA interference. The synthesis of biopolymers and biologically active molecules remains an important task in chemical biology, as it 1) gives access to natural compounds, which otherwise could be isolated only in small and insufficient amounts; 2) allows the synthesis of modified or non-natural analogs or intermediates of natural compounds; and 3) provides tool compounds for the investigation of biologic mechanisms.
Although Emil Fischer had already pioneered the synthesis of sugars, nucleobases, and oligopeptides at the beginning of the twentieth century, the synthesis of these biomolecules in solution involved multistep sequences with many tedious workup and purification operations. Bruce Merrifield recognized that their syntheses can be simplified if a substrate is immobilized on an insoluble polymeric support ("resin") via a linker unit (1). Once immobilized the substrate can be easily modified by adding an excess of reagents and building blocks to ensure complete conversion. Consumed and excess reagents are then easily removed by washing the support and by simple filtration. Finally, cleavage of the linker releases the desired product into the solution allowing its isolation in pure form (Fig. 1).
Figure 1. General flow scheme of solid-phase synthesis. The solid support is represented by the gray ball. In this cartoon, only one functional group is depicted instead of billions on a real bead.
Solid Support
A wide range of support materials exists for the heterogeneous immobilization of substrates in solid-phase synthesis, each offering certain advantages in different applications (2, 3). Parameters to be considered are 1) loading (= mmol of functional groups per gram support), 2) bead size (measured in "mesh"), 3) swellability in solvents (degree of cross-linking and hydrophilicity), and 4) mechanical stability (mechanical abrasion interferes with filtration workup). As more than 99.99% of the substrate molecules are buried within the gel matrix of a polymeric bead, the resin must be swollen by solvent molecules to allow access to reagents. Polystyrene (PS) resins (cross-linked with 1-2% divinylbenzene (DVB), loading up to 2 mmol functional group/g) are the resins most commonly used for oligopeptide and small-molecule solid-phase synthesis. These resins swell in most organic solvents but not in very polar solvents such as alcohols or water. If reactions need to be performed under polar conditions, the use of Tentagel (PS-resin with grafted polyethyleneglycol chains), PEGA, Pepsyn, or Argogel is recommended because these substances are distinguished by polar, flexible, polymeric chains. Highly cross-linked macroporous resins (e.g., Argopore) exhibit a solvent-independent permanent pore structure and can be used in any solvent. For oligonucleotide synthesis, controlled pore glass (CPG), which is an inorganic support with well-defined, large pores, is widely used. The low loading and high cost of this material are compensated by the operational advantage of good accessibility in any solvent. Recently, the synthesis of biopolymers on planar surfaces, such as glass (DNA-chips) (4) or cellulose membranes (SPOT-synthesis), (5) has gained increasing attention.
A linker can be considered as a polymeric (or, more general, immobilized) protecting group. It is a functional group responsible for the covalent attachment of the substrate onto the support that will be cleaved from the product at the end of the synthesis sequence. The following features have to be considered when choosing an appropriate linker: 1) The attachment of substrate should proceed in high yield, 2) the linker should be stable under all reaction conditions considered for the synthetic sequence ("orthogonality"), and 3) the linker should be cleaved under mild conditions in quantitative yield without obscuring the integrity and purity of the product. More than 200 different linkers have been described exhibiting different degrees of orthogonality and releasing different functionalities at the product after cleavage (6, 7). Cleavage of the linker can be initiated by the addition of acid (commonly used in oligopeptide synthesis), base (used in DNA-synthesis), metals, oxidation, reduction, or light (photocleavable linker). Linkers that release their product without any visible functional group are named "traceless linkers." "Safety-catch linkers" require two different chemical reactions in order to undergo cleavage, which offers a unique degree of stability. In Fig. 2 some frequently used linkers and the corresponding cleavage conditions are depicted.
Figure 2. Representative linkers frequently used in solid-phase synthesis. The molecular moiety depicted in blue represents the molecule that is released upon cleavage of the linker. DCM = dichloromethane, TFA = trifluoroacetic acid.
As solid-phase synthesis basically involves only three types of operations (addition of excess of reagent; shaking the beads in the reagent cocktail; filtration and washing) machines have been designed to perform solid-phase synthesis automatically (8). Automated oligonucleotide and oligopeptide synthesis has become routine.
Synthesis of Biopolymers
The solid-phase synthesis of biopolymers via iterative coupling of monomeric building blocks has found widespread application. It can be adapted easily for the incorporation of non-natural building blocks or labeled monomers, which will be used as probe molecules in chemical biology.
Synthesis of Oligopeptides and Proteins
Oligopeptides are synthesized on solid phase from the C- to the N-terminus. Depending on the N-terminal protecting group of the amino acid building blocks, two different strategies can be followed. In the "Boc-strategy," the tert.-butyloxycarbonyl-protecting group is cleaved by addition under acidic conditions (trifluoroacetic acid), which requires a linker that is resistant to these conditions because it is either cleaved only by very strong acids (HF, trifluoromethanesulfonic acid) or by a different agent (Fig. 3) (1). The "Fmoc-strategy" is based on the fluorenylmethoxycarbonyl-protecting group, which is cleaved by addition of 20% piperidine/DMF. It has the advantage that the important class of acid labile linkers (e.g., Wang-linker or Rink-linker) is compatible with this approach.
Figure 3. Flow scheme of a solid-phase synthesis of an oligopeptide following the Boc-strategy. The first amino acid is attached to the Merrifield linker by alkylative esterification of its cesium-salt. After acidic deprotection of the Boc-group and neutralization, the N-terminus undergoes DCC-mediated coupling with another Boc-protected amino acid building block. This sequence can be iterated, leading to even longer oligopeptides. Finally, the protect is released upon cleavage with HF. DCC = dicyclohexylcarbodiimide.
In addition, measurement of the UV-absorption of the cleaved protecting group allows the determination of the yield of the previous coupling operation. In practice, oligopeptides with up to 50 amino acids can be synthesized on solid phase. Instrumental for achieving reasonable yields for long oligomers is an almost perfect conversion for each deprotection and coupling step, for which a plethora of modern peptide coupling reagents are available; the coupling reagents also minimize epimerization (9). The synthesis of larger proteins (>60 aa) may be accomplished by preparation of fragments on solid phase that are then assembled using solution-phase ligation reactions (10), such as the native chemical ligation using an N-terminal Cys-residue (11). Table 1 lists representative examples of de novo synthesized proteins using solid-phase peptide synthesis. Recently, the combination of expressed protein ligation and solid-phase peptide synthesis has emerged as a powerful tool for the preparation of proteins with unnatural modifications or labels (12). Solid-phase peptide synthesis has reached a level where the ton-scale synthesis of peptide drugs, such as the HIV drug Enfuvirtide (a 36mer peptide), has been established.
Table 1. A selection of notable examples for the total solid-phase synthesis of proteins
Merrifield et al.
Ribonuclease A
Sigler et al.
Apolipoprotein CI
57 aa
Fairwell et al.
Human parathyroid hormone
S -carbamoylmethyl bovine apocytochrome c
Wlodawer et al.
HIV-Protease
Briand et al.
Ubiquitin
Di Bello et al.
Horse heart cytochrome C
Lu et al.
Bovine pancreatic trypsin inhibitor
Kaiser et al.
Macrophage migration inhibitory factor
Canne et al.
Human group V secretory phospholipase A2
Hackeng et al.
Human matrix Gla protein
Miranda et al.
Human S100A12
Low et al.
cytochrome b562
Becker et al.
Ras + Raf
166 + 81 aa
Kochendoerfer et al.
Erythropoietin
Vpu
Cabrele et al.
aa = amino acid.
Synthesis of Oligonucleotides
The solid-phase synthesis of DNA oligomers has reached a high level of maturity and is extensively used for the synthesis of primers for polymerase chain reaction or the design of new genes (13). In contrast to the cellular process, the synthetic route forms the polymer in 3'-to-5' direction. The oligomerization is carried out on CPG using a base labile linker. Typically, the nucleobases are introduced as acyl-protected phosphoramidites, which will be oxidized to phosphates after each elongation step (14). Treatment with base leads to global deprotection (nucleobase protecting groups and the cyanoethyl protecting group at phosphate) and cleavage of the oligonucleotide from the solid support. The conversion of each coupling step can be monitored by UV measurement of the dimethoxytrityl-carbocation, which is generated by the deprotection of the 5'-OH before each new coupling cycle (Fig. 4). The introduction of non-natural or modified nucleobases can be easily accomplished by using a corresponding phosphoramidite building block during the synthetic sequence.
Figure 4. Flow scheme of the synthesis of DNA-oligonculeotides using the phosphoramidite method. DMT = dimethoxytrityl, TCA = trichloroacetic acid.
The synthesis of RNA-oligomers (e.g., needed for applications in RNAi, aptamers, or as ribozymes) follows the steps described above for DNA but requires the protection of the 2'-OH group, for which the 2'O-TOM- and the 2'O-ACE protecting groups are most often used (Fig. 5) (15).
PNA-oligomers are synthesized using methodology developed for peptide synthesis. The large-scale synthesis of oligonucleotides has been established for the preparation of sufficient quantities for clinical trials of antisense drugs.
Figure 5. Most frequently used 2'-OH protecting groups in RNA-oligomer synthesis. DMF = N,N-dimethylformamide, PG = protecting group.
Synthesis of Oligosaccharides
The automated solid-phase synthesis of oligosaccharides is expected to have a tremendous impact in glycobiology as many natural proteins are decorated by complex oligosaccharide conjugates that strongly influence the biologic activity of the conjugate. Recently, the first examples of automatically synthesized oligosaccharides have been reported (16). The availability of appropriately protected building blocks and the creation of certain linkage patterns remain as challenges in this field.
Solid-Phase Synthesis of Small Molecules
Protein function can be modulated by small-molecule ligands. Offering complementary advantages to mutation genetics, the search for small molecules as molecular probes for the investigation of biologic systems has gained new interest ("chemical genetics"). In addition, high-throughput screening efforts in hit finding and lead optimization in drug discovery require large collections of small molecules ("molecular libraries"). Solid-phase synthesis has strongly contributed to these efforts as it gives fast access to large compound libraries.
Combinatorial Synthesis
In the early 1990s combinatorial chemistry was developed as a tool for the production of large oligopeptide libraries (17-19). Following a split-mix strategy depicted in Fig. 6, libraries with millions of different compounds can be created. This approach was extended by Ellman and colleagues for the synthesis of small-molecule libraries (20). Diversity-oriented synthesis (DOS) has been invented as a powerful tool for the synthesis of very large structurally diverse compound libraries (21). For the identification of the active compound, several strategies, such as on-bead-screening, deconvolution, or encoding, have been established. The use of "IRORI-kans" (penetrable little containers filled with beads and labeled either with a radio-frequency tag or an optical bar code on the container lid) allows the synthesis of mg-quantities of compounds in a split-mix -format, which offers the additional advantage of having the synthetic history of each kan monitored by a computer-based readout system of the radio-frequency tag or the optical bar code) (22).
Figure 6. Combinatorial synthesis using a split-mix format. Building blocks are added separately in different vials, but the beads with reaction products are pooled before being distributed again before the next reaction step. Each vial contains all combined products of the previous reaction steps, but each bead contains only a single compound.
Natural Product Libraries
Several of the most useful small-molecule probes are complex natural products isolated from marine, fungal, or plant sources. As natural products have built-in biologic properties efforts in the synthesis of compound libraries increasingly use natural product scaffolds as a starting material because they promise higher hit rates in biologic screens (23).
In Fig. 7 a few representative examples of molecular probes identified by screening of combinatorial libraries are depicted.
Figure 7. Selected examples of tool compounds identified by screening of combinatorial small-molecule libraries.
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17. Furka A, Sebestyen F, Asgedom M, Dibo G. General method for rapid synthesis of multicomponent peptide mixtures. Int. J. Pept. Protein. Res. 1991; 37:487-493.
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Diversity-Oriented Synthesis of Small Molecules
Natural Product Inhibitors to Study Biological Function
Nucleic Acid Synthesis, Key Reactions of
Proteins: Structure, Function and Stability
Solution-Phase Synthesis of Biomolecules


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