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With the end of the Macedonian Wars – which ran concurrently with the Punic Wars – and the defeat of the Seleucid King Antiochus III the Great in the Roman–Seleucid War (Treaty of Apamea, 188 BC) in the eastern sea, Rome emerged as the dominant Mediterranean power and one of the most powerful cities in classical antiquity. The Roman victories over Carthage in these wars gave Rome a preeminent status it would retain until the 5th century AD.
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