هل   وأولانزابين  هو من الأدوية المقاومة للفصام؟
Olanzapine, sold under the trade name Zyprexa among others, is an antipsychotic medication primarily used to treat schizophrenia and bipolar disorder. For schizophrenia it is used for both new onset disease and long term maintenance. It is taken by mouth or by injection into a muscle.
Common side effect include weight gain, movement disorders, dizziness, feeling tired, constipation, and dry mouth. Other side effects include low blood pressure with standing, allergic reactions, neuroleptic malignant syndrome, high blood sugar, seizures, gynecomastia, and tardive dyskinesia. In older people with dementia, its use increases the risk of death. Use in the later part of pregnancy may result in a movement disorder in the baby for some time after birth. How it works is not entirely clear, however, may include the blocking of dopamine receptors and serotonin receptors. It is classed as an atypical antipsychotic.
Olanzapine was patented in 1971 and approved for medical use in the United States in 1996. It is available as a generic medication. In the United States the wholesale cost is less than 0.25 per dose as of 2018. In 2016 it was prescribed more than 2 million times in the United States.
no