不斉補助剤が初めて作られたのはいつ？
Chiral auxiliaries were introduced by E.J. Corey in 1975 with chiral 8-phenylmenthol and by B.M. Trost in 1980 with chiral mandelic acid. The menthol compound is difficult to prepare and as an alternative trans-2-phenyl-1-cyclohexanol was introduced by J. K. Whitesell in 1985.
1975